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1 se, 2-oxoglutarate dehydrogenase and glycine decarboxylase).
2 d the GABA-synthesizing enzyme glutamic acid decarboxylase.
3 ehydrogenase and a subsequent glutaconyl-CoA decarboxylase.
4 synthesized putrescine via a SpeC ornithine decarboxylase.
5 synthase reaction involves a glycyl radical decarboxylase.
6 70 interacts with TH and aromatic amino acid decarboxylase.
7 lipoylation of the photorespiratory glycine decarboxylase.
8 pression level of Cmoxdc1 coding for oxalate decarboxylase.
9 ggering degradation of its target, aspartate decarboxylase.
10 ompetitive substrate, or inhibitors of human decarboxylase.
11 arboxylate levodopa to dopamine via tyrosine decarboxylases.
13 ed conditional null alleles of Glutamic acid decarboxylase 1 (Gad1) and Resistant to dieldrin (Rdl),
14 used by epigenetic upregulation of glutamate decarboxylase 1 (GAD1), a regulator of the GABA neurotra
15 a-aminobutyric acid (GABA) and glutamic acid decarboxylase 1 (GAD1), the enzyme that synthesizes GABA
16 show that this mechanism requires aconitate decarboxylase 1 (IRG1), which synthesizes itaconate, a m
17 ), which is a suicide inhibitor of ornithine decarboxylase 1 (ODC1), and diethylnorspermine (DENSpm),
18 nd polyamine metabolism, including Ornithine Decarboxylase 1 (ODC1), are affected by DNA methylation
19 hibits the expression of c-MYC and ornithine decarboxylase 1 (ODC1), the rate-limiting enzyme for pol
23 RNA-sequencing demonstrated Acod1 (Aconitate decarboxylase 1) as one of the top genes induced by PM i
25 ynaptosomal-associated protein 29, glutamate decarboxylase 1, metabotropic glutamate receptor 1, and
26 n antizyme-mediated degradation of ornithine decarboxylase-1 and a resulting reduction in cellular po
28 ctivated a small population of glutamic acid decarboxylase 2 (GAD2)-expressing neurons in the lateral
29 ne released from neurons expressing tyrosine decarboxylase 2 (Tdc2) signal directly to astrocytes to
31 ed autoantigens [proinsulin or glutamic acid decarboxylase 65 (GAD)] delayed T1D onset, but published
34 ed, including orexin cells and glutamic acid decarboxylase 65 (GAD65) cells, but their interplay in o
35 cond GABA-synthesizing enzyme, glutamic acid decarboxylase 65-kDa isoform (GAD65), remains unclear.
36 lsed with preproinsulin (PPI), glutamic acid decarboxylase (65-kDa isoform; GAD65), and insulinoma-as
37 ATP-alpha, but increased levels of glutamate decarboxylase-65 and glutamine synthetase in PFC; reduce
38 sion levels of parvalbumin and glutamic acid decarboxylase 67 (GAD67) in schizophrenia subjects but n
39 istently found lower levels of glutamic acid decarboxylase 67 (GAD67) messenger RNA (mRNA) in the pre
40 ychiatric candidate promoters (glutamic acid decarboxylase 67, Reelin, and brain-derived neurotrophic
41 f the GABA-synthesizing enzyme glutamic acid decarboxylase 67-kDa isoform (GAD67) in the PFC have bee
42 lpha-amino-beta-carboxymuconic--semialdehyde decarboxylase, a class III amidohydrolase, with a single
43 chanisms, with reduced aromatic L-amino acid decarboxylase (AAAD) activity closely related to the app
44 sphate (PLP)-dependent aromatic l-amino acid decarboxylase (AAAD) family has yielded an array of para
45 , is biosynthesized by aromatic-L-amino acid decarboxylase (AADC) and indolethylamine-N-methyltransfe
50 ne substitution in the L-aromatic amino acid decarboxylase (AADC) enzyme was replicated in a meta-ana
51 ygous mutations in the aromatic l-amino acid decarboxylase (AADC) gene result in a severe depletion o
52 o its decarboxylation by aromatic amino acid decarboxylase (AADC), an enzyme overexpressed in these m
53 sine hydroxylase (TH), aromatic l-amino acid decarboxylase (AADC), and GTP cyclohydrolase I (GCH1) tr
54 amine transporter (DAT), aromatic amino acid decarboxylase (AADC), or vesicular monoamine type 2 were
55 lly express the enzyme aromatic L-amino acid decarboxylase (AADC), which synthesizes trace amines dir
56 tionally characterized aromatic l-amino acid decarboxylases (AADCs) and aromatic aldehyde synthases (
58 ing reaction, ACMS is decarboxylated by ACMS decarboxylase (ACMSD) for further metabolism and energy
59 ha-Amino-beta-carboxymuconate-e-semialdehyde decarboxylase (ACMSD) plays an important role in l-trypt
61 te with enhanced aconitase and cis-aconitate decarboxylase activities by controlling the expression o
67 dc1 is solely responsible for the reversible decarboxylase activity, and that it requires a new type
68 ved to be initiated by a change in glutamate decarboxylase activity, but the underlying mechanisms ar
73 proteins in mtacp mutants, particularly Gly decarboxylase, affects the recovery of photorespiratory
74 s of Trypanosoma brucei S-adenosylmethionine decarboxylase alone and in functional complex with its c
75 hey are both functional meso-diaminopimelate decarboxylases, although with lower activities than thos
76 pyruvoyl cofactor of S-adenosyl-L-methionine decarboxylase (AMD1) is dynamically controlled by intrac
77 remains unknown whether adenosyl methionine decarboxylase (AMD1), a rate-limiting enzyme in polyamin
80 made possible by the evolution of a pyruvate decarboxylase, analogous to that in brewer's yeast and t
83 lso analyzed the expression of the Histidine decarboxylase and ECP by flow cytometry and fluorescence
84 patients express higher levels of histidine decarboxylase and ECP than those from healthy volunteers
85 e show that cholangiocytes express histidine decarboxylase and its inhibition reduces CCA growth.
86 ania donovani have shown that both ornithine decarboxylase and spermidine synthase, two enzymes of th
87 synthesis-responsive genes, namely ornithine decarboxylase and spermidine synthase, were induced by G
88 tudy, we describe the use of tyrosinases and decarboxylases and combine these with a transaminase enz
90 e biosynthesis (spe1Delta, lacking ornithine decarboxylase, and spe2Delta, lacking SAM decarboxylase)
91 y, many patients with SPS have glutamic acid decarboxylase antibodies (GAD-ab), but these 2 disorders
93 itions, retinopathy, and serum glutamic acid decarboxylase antibody (GADA) titers in relation to reti
94 ral interactive partners, of which ornithine decarboxylase antizyme-1, NEEP21 (NSG1), and ADAM10 were
95 ornithine and polyamine synthesis, ornithine decarboxylase appeared to be the rate-limiting enzyme fo
96 Arginase, arginine deiminase and arginine decarboxylase are potential enzymes that may be used for
98 techols, employing 3,4-dihydroxybenzoic acid decarboxylases (AroY) that belong to the UbiD enzyme fam
99 ses identify an operon encoding oxaloacetate decarboxylase as diagnostic for the tongue-abundant subg
100 rom incomplete catalysis by TpcK (a putative decarboxylase), as its deletion results in a nearly 10-f
101 her relative abundance of bacterial tyrosine decarboxylases at the site of levodopa absorption, proxi
103 8)F]FMT; a substrate for aromatic amino acid decarboxylase), baseline D2/3 receptor-binding potential
107 of triarylmethanols, and (3) benzoylformate decarboxylase-catalyzed enantioselective benzoin condens
111 A member of the PdxA family of oxidative decarboxylases catalyzes a novel decarboxylation that us
112 e 4-phosphate dehydrogenase (PdxA) oxidative decarboxylase, class II aldolase, or ribulose 1,5-bispho
120 idase (MAO) and L-3,4-dihydroxyphenylalanine decarboxylase (DDC) for microbe-based production of tetr
122 l-carbidopa, which is known to inhibit DOPA decarboxylase (DDC), a key protein in Parkinson's diseas
123 identified one dopamine synthesis gene, DOPA decarboxylase (DDC), as a suppressor of tau toxicity in
124 uences of tyrosine hydroxylase (TH) and dopa decarboxylase (DDC), two key enzymes in the biosynthesis
126 in, and trace amines, relies in part on DOPA decarboxylase (DDC, AADC), an enzyme that is required fo
127 PS's classification as a carboxy-lyase (i.e. decarboxylase), decarboxylation is not a completely esse
129 congeners originates from the activity of a decarboxylase-dehydrogenase enzyme with high similarity
130 (a-FMHis), a suicide inhibitor of histidine decarboxylase, displayed impaired IA memory when tested
131 a drug that targets host aromatic amino acid decarboxylase does not prevent gut microbial l-dopa deca
133 Certain host cells express the histidine decarboxylase enzyme (HDC), which is responsible for cat
134 d carbon nanotubes (MWCNT-COOH), and oxalate decarboxylase enzyme (OxDc) immobilized onto a carbon cl
135 esis, of the bacillaene synthase dehydratase/decarboxylase enzyme couple PksH/PksI, responsible for t
138 t through direct activation of glutamic acid decarboxylase enzyme isoforms that convert glutamate to
140 atidylserine catalyzed by phosphatidylserine decarboxylase enzymes (PSD) as a suitable target for dev
141 POMC neurons, as these encode the glutamate decarboxylase enzymes GAD67 and GAD65, respectively.
144 arousal states, is synthesized in histidine decarboxylase-expressing hypothalamic neurons of the tub
145 line expressing cre recombinase in histidine decarboxylase-expressing neurons (Hdc-Cre) followed by a
146 at members of the beta-hydroxyacid reductive decarboxylase family employ different active site featur
148 cterization studies of a novel phenylacetate decarboxylase from an anaerobic, sewage-derived enrichme
150 by a pyridoxal phosphate-dependent tyrosine decarboxylase from Enterococcus faecalis is followed by
153 tyric acid synthesizing enzyme glutamic acid decarboxylase (GAD) and choline acetyltransferase (ChAT)
154 th region-specific changes in glutamate acid decarboxylase (GAD) and vesicular GABA transporter expre
155 h levels of antibodies against glutamic acid decarboxylase (GAD) are observed in patients with differ
157 ed by enzymes derived from two glutamic acid decarboxylase (GAD) genes, GAD1 and GAD2, both of which
160 ainst tyrosine hydroxylase (TH) or glutamate decarboxylase (GAD) to systematically compare the propor
161 s and activity measurements of glutamic acid decarboxylase (GAD), a PLP-dependent enzyme synthesizing
162 hosphate-diaphorase (NADPH-d), glutamic acid decarboxylase (GAD), cytochrome oxidase (CO), and calret
166 , we study the distribution of glutamic acid decarboxylase (GAD)67 and GLY transporter 2 (T2) in axon
168 factor, which we report to bind to glutamate decarboxylase (Gad1), which encodes GAD67, a rate-limiti
169 orters (vglut1, vglut2.1, vglut3), glutamate decarboxylases (gad1, gad2), and choline acetyltransfera
171 UT1) and the 65 kDa isoform of glutamic acid-decarboxylase (GAD65) as markers of, respectively, Ia af
172 st insulin, the 65-kDa form of glutamic acid decarboxylase (GAD65), insulinoma-associated protein 2 (
173 oded 67-kDa protein isoform of glutamic acid decarboxylase (GAD67) is a hallmark of schizophrenia.
174 evels of the 67 kDa isoform of glutamic acid decarboxylase (GAD67) protein, the enzyme responsible fo
175 vels of tyrosine hydroxylase (TH), glutamate decarboxylase (GAD67), and vesicular glutamate transport
176 contain the 67 kDa isoform of glutamic acid decarboxylase (GAD67-GFP), or Cre-recombinase in cells t
179 photosynthesizing tissue is used for glycine decarboxylase (GDC), necessary for the high-flux photore
180 partate semialdehyde dehydrogenase, arginine decarboxylase gene activator, GTP cyclohydrolase I and a
182 omato plants over-expressing mouse ornithine decarboxylase gene under the control of fruit-specific p
183 es an upregulation of the insect's ornithine decarboxylase gene, which sequesters arginine for polyam
184 pression and activity of three tea glutamate decarboxylase genes (CsGAD1, 2, and 3), and their encode
187 associated with loss of function of glycine decarboxylase (Gldc) in mice and in humans suffering fro
188 re, we report that the gene encoding glycine decarboxylase (GLDC), which catalyzes the first and rate
189 a triplication of the gene encoding glycine decarboxylase, GLDC, presumably resulting in reduced ava
190 e, catalase, superoxide dismutase, ornithine decarboxylase, glutamate receptor, and ammonia transport
191 -malic enzyme (ME), the most widespread C(4) decarboxylase, has increased its catalytic efficiency an
195 s on dietary histidine and also on histidine decarboxylase (Hdc) depends upon their growth requiremen
196 in one integrated device to detect histidine decarboxylase (HDC) gene directly from human white blood
197 carboxypeptidase A3 (CPA3), and L-histidine decarboxylase (HDC) gene expression; and serum markers (
198 ure termination codon in the human histidine decarboxylase (Hdc) gene has been identified in a family
202 crystal structure of a Pseudomonas malonate decarboxylase hetero-tetramer, as well as biochemical an
204 a NIS synthetase FslA/FigA and an ornithine decarboxylase homolog FslC/FigC, required for rhizoferri
205 antigens are established (insulin, glutamate decarboxylase, IA2, and zinc transporter-8), but the mol
206 ctures of Escherichia coli methylmalonyl-CoA decarboxylase in complex with our analogs affords insigh
207 the GABA-synthesizing enzyme, glutamic acid decarboxylase in EC were confirmed by immunostaining and
209 c protein-immunocytochemistry, glutamic acid decarboxylase in situ hybridization, and parvalbumin-imm
210 n addition, we identified TbPSD as type I PS decarboxylase in the mitochondrion and found that it is
211 ically, that abundance of bacterial tyrosine decarboxylase in the proximal small intestine can explai
212 bunit of the photorespiratory enzyme glycine decarboxylase, increased accumulation of glycine and gly
214 amine analog and potent S-adenosylmethionine decarboxylase inhibitor, decreases HIV expression in mon
215 difluoromethylornithine (DFMO), an ornithine decarboxylase inhibitor, may further decrease immunosupp
217 dual function enzyme, mevalonate 5-phosphate decarboxylase is unable to carry out the first phosphory
218 romoter regulatory elements of glutamic acid decarboxylase isoforms (Gad1 and Gad2), which regulate G
219 two putative eukaryotic meso-diaminopimelate decarboxylase isoforms from the plant species Arabidopsi
220 also improved by overexpression of keto-acid decarboxylases (KDC) and alcohol dehydrogenase (ADH).
223 identified the pyridoxal phosphate-dependent decarboxylase-like proteins in the translated proteome o
225 cteria contain a biotin-independent malonate decarboxylase (MDC), which allows them to use malonate a
226 with a distinct prosthetic group, as well as decarboxylase (MdcD-MdcE) and acyl-carrier protein trans
227 zyme in this pathway, mevalonate diphosphate decarboxylase (MDD), acts on mevalonate diphosphate (MVA
231 ls (RWPE-1) with overexpression of ornithine decarboxylase (ODC) and used it for in vitro and in vivo
232 descendants, we observed increased ornithine decarboxylase (ODC) enzymatic activity and concentration
234 alpha-difluoromethylornithine, an ornithine decarboxylase (ODC) inhibitor, and entered into DU145 ce
235 of Ptch1 haploinsufficiency on an ornithine decarboxylase (ODC) transgenic background (Ptch1(+/-)/OD
239 The plasma levels of arginase I, ornithine decarboxylase (ODC), transforming growth factor beta (TG
242 e deletion of the orotidine 5'-monophosphate decarboxylase (OMPDC) and uridine phosphorylase (UP) gen
244 to insulin, autoantibodies to glutamic acid decarboxylase or insulinoma-associated antigen 2, or dia
246 d, in microorganisms, the action of pyruvate decarboxylase (PDC) and pyruvate formate lyase (PFL)-enz
248 iosynthesis, and identified a melon pyruvate decarboxylase, PDC1, that is highly expressed in ripe fr
249 Microorganisms - CCDM 824 and CCDM 946) with decarboxylase positive activity in a model system of Dut
250 in the ganglion cell layer is glutamic acid decarboxylase-positive and shows the morphology of widef
251 e formation of an unusual heterotrimeric PPC decarboxylase (PPCDC) complex crucial for CoA biosynthes
255 e first report in a virus of a phenolic acid decarboxylase, proteasomal subunit, or cysteine knot (de
256 ay by an inhibitor of arginase and ornithine decarboxylase protected the mice from AD-like pathology
257 ine hydroxylase (TH) and aromatic amino acid decarboxylase, providing a novel mechanism for dopamine
258 , we demonstrate that the phosphatidylserine decarboxylase Psd1, located in the inner mitochondrial m
259 of a key pathway enzyme, phosphatidylserine decarboxylase Psd1, which generates phosphatidylethanola
265 This first-time study of the phenylacetate decarboxylase reaction constitutes an important step in
266 DFMO), known to inhibit the enzyme ornithine decarboxylase, reduces H. pylori-mediated gastric cancer
267 ne decarboxylase, and spe2Delta, lacking SAM decarboxylase) require externally supplied polyamines, b
268 In addition, higher expression of lysine decarboxylase resulted in a prolonged survival among ear
269 stal structure of the FigC N-citrylornithine decarboxylase reveals how the larger substrate is accomm
271 variants of yeast orotidine 5'-monophosphate decarboxylase (ScOMPDC) at pD 8.1, and by the Q215A vari
272 erase (ScTIM), yeast orotidine monophosphate decarboxylase (ScOMPDC), and human liver glycerol 3-phos
273 cultured MCs were transfected with histidine decarboxylase short hairpin RNA to decrease histamine se
275 trastructure, and tissue localization of Gly decarboxylase subunit P (GLDP) in nine Neurachninae spec
276 by inserting Shigella glutaminase-glutamate decarboxylase systems coexpressed with S. sonnei form I
277 ucei PS synthase 2 (TbPSS2) and T. brucei PS decarboxylase (TbPSD), two key enzymes involved in amino
279 e only known pyridoxal-5-phosphate-dependent decarboxylase that catalyzes the removal of a carboxyl g
280 bacteria have a biotin-independent malonate decarboxylase that is crucial for their utilization of m
281 lornithine, and FigC is an N-citrylornithine decarboxylase that together synthesize rhizoferrin witho
282 amily of alanine racemase-fold PLP-dependent decarboxylases that are not involved in polyamine biosyn
283 al malic enzymes (ME2 and ME3) are oxidative decarboxylases that catalyse the conversion of malate to
285 revealed colocalization of DA, l-amino acid decarboxylase, the DA transporter, and vesicular monoami
286 ntibodies directed against the glutamic acid decarboxylase, the rate-limiting enzyme for the producti
288 g pathway regulates translation of ornithine decarboxylase, thereby enhancing polyamine biosynthesis
289 the first characterized example of a diiron decarboxylase, thus expanding the repertoire of reaction
290 used immunohistochemistry for glutamic acid decarboxylase to distinguish GABAergic from glutamatergi
292 C supernatant fluids increased CCA histidine decarboxylase, vascular endothelial growth factor, and M
294 nerate mevalonate 3,5-bisphosphate and a new decarboxylase we describe here, mevalonate 3,5-bisphosph
295 pressing different isoforms of glutamic acid decarboxylase were found to have differential subregiona
296 e levels of mitochondrial phosphatidylserine decarboxylase, which is involved in the synthesis of mit
297 racterization of a branched-chain amino acid decarboxylase, which would appear to be responsible for
298 me complex that have evolved into a pyruvate decarboxylase, while other copies retained the essential
299 we also determine the structure of malonate decarboxylase with CoA in the active site of MdcD-MdcE.
300 he reaction of the UbiD-related ferulic acid decarboxylase with substituted propenoic and propiolic a