ライフサイエンスコーパス: decline

1 would drop to 0.6 per 100 person-years (76% decline).

2 , only AT FTP significantly predicted memory decline.

3 tau pathology, and predicts future cognitive decline.

4 ells contributes to aged muscle regenerative decline.

5 s have played a key role before their recent decline.

6 , Robusta: 364 mg/kg) followed by a distinct decline.

7 disease (AD), since it drives the cognitive decline.

8 ndrogens do not demonstrate an age-dependent decline.

9 understood about what is contributing to the decline.

10 y a brief fast decline and then a slow final decline.

11 h should affect the kinetics of plasma-virus decline.

12 ion and alleviate aging-associated cognitive decline.

13 ation difficulties, isolation, and cognitive decline.

14 rol mechanisms are all hallmarks of cellular decline.

15 d treatments exist for age-related cognitive decline.

16 concentrations, predicted greater spirometry decline.

17 aternal nutrition as key drivers of stunting decline.

18 nvironment to ensure that levels continue to decline.

19 an early sign of potential future cognitive decline.

20 s help explain widespread bumble bee species decline.

21 ion at baseline and lower rates of cognitive decline.

22 ulture, but their numbers have significantly declined.

23 T cells increased while plasma BKPyV-DNAemia declined.

24 ntiate, the amount of RBR and E2FB gradually declined.

25 letal injuries and contributes to functional declines.

26 egrees C, chironomid diversity stabilizes or declines.

27 l emissions decrease over time as production declines.

28 us, with a broad range of rates of cognitive decline(1).

29 cross all ages, mortality resulting from CHD declined 39.4% overall.

30 metastatic disease (including 2 patients who declined additional treatment).

31 nst Env-expressing target cells but began to decline after 3 to 6 weekly doses, coincident with the d

32 Residual global cognitive decline after adjustment for neuropathologic burden was

33 let autoantibodies (2 [1-4]) (P = .002), but declined after 12 months of follow-up (2 [0-4]) (P < .00

34 In contrast, mortality from SCLC declined almost entirely as a result of declining incide

35 y slows Caenorhabditis elegans' reproductive decline, an early hallmark of aging in many animals.

36 s in molecular pathways related to cognitive decline and Alzheimer's disease.

37 roteinuria is associated with renal function decline and cardiovascular mortality.

38 thus, a response to coeval atmospheric CO(2) decline and continental-scale Antarctic glaciation.

39 that it is also a risk factor for cognitive decline and dementia.

40 nd is associated with significant functional decline and distress.

41 hat gypsum scaling caused earlier water flux decline and induced membrane wetting that was not observ

42 inty, such as when the resource is in subtle decline and intragroup communication sparse.

43 dementia, also results in gradual cognitive decline and is thought to arise, in part, because of a c

44 d hippocampal volumes, age-related cognitive decline and psychiatric disorder risk.

45 e of radioactivity, followed by a brief fast decline and then a slow final decline.

46 over time, causing metamorphopsia and visual decline and therefore these lesions warrant continued cl

47 conservation targets to reverse biodiversity declines and halt species extinctions are not being met

48 a link between global vehicle transportation declines and the reduction of ambient NO(2) exposure.

49 e the mechanisms underpinning bee population declines and to improve the health of both wild and mana

50 ulations to understand if concentrations are declining and how levels relate to toxicological thresho

51 primary meta-analysis, 8 reported cognitive decline, and 8 reported changes in cognitive test scores

52 ne whether PM2.5 affects the episodic memory decline, and also explored the potential mediating role

53 the development of sporadic AD and cognitive decline, and changes in structural brain characteristics

54 show that the global extent of river ice is declining, and we project a mean decrease in seasonal ic

55 rt (CPUE), and lionfish tournament CPUE also declined approximately 50% in 2018.

56 ose at risk for AD and age-related cognitive decline (ARCD) in order to develop preventative treatmen

57 s at higher water arsenic quantiles indicate declines are related to MCL implementation.

58 imum conditions, the electrochemical signals declined as AFB1 concentrations increased with a dynamic

59 contribute significantly to the reproductive decline associated with advanced maternal age.

60 ine presented an increased risk of cognitive decline at 3 years (relative risk [RR] = 3.49, 95% confi

61 Antibodies to all PfEMP1 types declined at similar rates to the point of disappearance

62 ticularly as coral communities worldwide are declining at rapid rates.

63 to 2014, revealing that both song types are declining at similar rates.

64 ven as the extreme pressures they face cause declining availability.

65 relative effect of major drivers of stunting decline between countries.

66 ng for clustering and age, the difference in decline between the 2 treatment arms was not significant

67 or deficit, dysphagia, and incontinence have declined between 2001 and 2018.

68 ute age-standardized CVD mortality gap would decline by 33.3% (95% CI 25.1-40.1) among men and 22.1%

69 ut any mitigation efforts are anticipated to decline by up to 2.8 m/year in some areas.

70 the control campus, CAUTI/1000 catheter-days declined by 68% versus 57% and catheter-days/patient dec

71 ecreased with the increase in shear rate and declined by increasing the temperature up to 50 degrees

72 This high level of mud supply had sharply declined by the early 20th century after a vast canal ne

73 ls declined by week 2, interleukin 18 levels declined by the end of treatment, sCD14 levels did not c

74 0 to 2017 by up to 97%, and their total area declined by up to 98%, despite increasing total producti

75 inducible protein 10, ATX, and Mac2BP levels declined by week 2, interleukin 18 levels declined by th

76 bility and a normal mean rate of age-related decline, consistent with largely nonprogressive peripher

77 n downstream performance, study 8 found that declining creativity beliefs negatively influenced task

78 In the crossflow protein concentration, flux decline curves were studied according to Hermia's foulin

79 logical or cognitive problems (eg, cognitive decline, depression, anxiety).

80 95% CI, 38.0 to 66.8; P<.001), but the FEV1 decline did not differ significantly (-34 vs -36 mL/y; d

81 The rise of antibiotic resistance and declining discovery of new antibiotics has created a glo

82 However, since neurogenesis declines dramatically with age, it is unclear how they m

83 Global biodiversity is undergoing rapid declines, driven in large part by changes to land use an

84 s from 55 moose in a population experiencing decline due to a myriad of factors, including pathogens

85 Quality of life (QOL) had declined due to severe pruritus, and they had striae and

86 Cardiac function declined during ESHP but was significantly better preser

87 munodominance of high-affinity T cell clones declined during the chronic infection phase, likely due

88 Marmot survival declined during winter but generally increased during su

89 Stabilizing the declining eastern migratory population of monarch butter

90 r survival and reproductive-status change to declining environmental quality result in a higher risk

91 lves, COVID(pos) patients distinctively show declining fibrinogen, increasing platelet counts, and lo

92 A declining first-phase insulin response (FPIR) is associa

93 CAAP rates markedly declined following 7- and 13-valent pneumococcal conjuga

94 may be useful in predicting future C-peptide decline for improved subject stratification in clinical

95 y night shift nurses experienced substantial decline-frequently into the "high risk" zone-throughout

96 r) as eGFR<60 ml/min per 1.73 m(2) and >=25% decline from baseline, CKD-related hospitalization or de

97 ddle adulthood, and by a lack of substantial decline from middle to old adulthood, which, however, wa

98 The number of counties producing each crop declined from 1940 to 2017 by up to 97%, and their total

99 All AMI risk-adjusted mortality rates also declined from 2006 to 2017 with 30-day post-discharge mo

100 best response, median serum immunoglobulin M declined from 3,520 to 821 mg/dL, bone marrow disease in

101 o 821 mg/dL, bone marrow disease involvement declined from 60% to 20%, and hemoglobin rose from 10.3

102 rtion of youth with poor diets significantly declined from 76.8% (95% CI, 72.9%-80.2%) to 56.1% (95%

103 Viral load declined from baseline with all GSK2838232 doses.

104 e show that JAK-STAT pathway activity, which declines from posterior to anterior, dictates the patter

105 Those costs are projected to decline further in the near future, bringing new prospec

106 family member migration status and cognitive decline; future work should be extended to other LMICs f

107 analyses revealed that clones may expand and decline, generally showing only a subtle increase in VAF

108 state-specific antigen (PSA)50 response (PSA decline >=50% at 12 wk vs. baseline).

109 ose initial drugs fail and ablation has been declined, has been unsuccessful, or has been deemed inap

110 However, declines have either not been universally observed in al

111 Nevertheless, water level declines have offset energy efficiency gains because of

112 outs) was well described by an exponentially declining hazard, with lower age, higher baseline Glasgo

113 density dependence to drive diversity, could decline in a future warmer, drier world.

114 he major pathological correlate to cognitive decline in AD.

115 on of the neurobiological bases of cognitive decline in aging populations may provide critical insigh

116 eimer's disease and a predictor of cognitive decline in aMCI.

117 s, PAM protein levels dropped, followed by a decline in ANP precursor (proANP) levels.

118 sening of glycemia associated with continued decline in beta-cell function.

119 An impaired decline in blood pressure at rest is typical in people w

120 al of HDAC1 activation to counter functional decline in brain aging and neurodegeneration.

121 ithin the IL-10(+) cluster had a significant decline in C-peptide levels in the period preceding the

122 asets of a wide range of markers highlight a decline in capillary and artery numbers, but not of peri

123 y damage of the myocardium and corresponding decline in cardiac function.

124 , morphine, and the combination promotes the decline in CD4(+) T cells in HIV-infected mice.

125 eased risk for graft failure (and functional decline in class 2 at 24 months postdiagnosis; serum cre

126 anol intake (1987-1998) with 15-year rate of decline in cognitive performance from mid- to late life

127 pment of the AD-like pathology and cognitive decline in DS, and for this reason the system could repr

128 me to a composite progression outcome (>=40% decline in eGFR, with eGFR<60 ml/min per 1.73 m(2), or E

129 e precipitation regimes, and that there is a decline in evolutionary diversity above 1,490 mm of mean

130 ension, type 2 diabetes (T2D), and cognitive decline in experimental models of IH patterned after O2

131 those with Q4 NfL values showed a -2.3 point decline in GCP score (-2.3 points, 95% CI = -4.7 to -0.9

132 e adducts were higher in patients with early decline in GFR, compared to those with stable GFR.

133 factorial process that is characterized by a decline in homeostatic capacity, best described at the m

134 There was significant daily decline in hospitalizations in March 2020 (-5.9% per day

135 s that increase acid excretion but lead to a decline in kidney function.

136 uces oxidant stress which contributes to the decline in kidney function.

137 suggest that the consequences of the ongoing decline in local newspapers will negatively affect socia

138 ted changes in haematopoiesis that include a decline in lymphopoiesis and skewing towards the myeloid

139 nts in diagnosis and treatment have led to a decline in mortality rates, morbidity rates have remaine

140 F versus those who achieved a 30% or greater decline in MRI-PDFF (MRI-PDFF responders) relative to ba

141 response in those who achieved less than 30% decline in MRI-PDFF versus those who achieved a 30% or g

142 tion of leaky vaccine effect to the observed decline in mVE.

143 s, distribute uniformly during the peak, and decline in numbers during later stages of EAE.

144 Reproductive decline in older female mice can be attributed to a fail

145 strategy for combating age-related cognitive decline in otherwise healthy individuals.

146 April and 24th May 2020, corresponding to a decline in patient admissions with COVID-19 during the o

147 Nonetheless, there is early evidence of a decline in per capita primary care visit rates, and litt

148 7%) of top-performing hospitals showed large decline in percentile rankings compared with baseline.

149 amyloid and tau is detrimental to cognitive decline in preclinical Alzheimer's disease during late m

150 The normal age-related decline in proportions of submucosal dopaminergic neuron

151 nd cardiovascular hospitalizations and slows decline in quality of life compared with placebo.

152 However, endemics with small ranges did decline in response to logging.

153 This decrease was related to a decline in SNF days per beneficiary (from 26.2 to 21.3 d

154 This is evident in the sharp decline in social mobility in the Midwest as economic ac

155 ere has been important work on mechanisms of decline in some species, it generally remains unclear wh

156 The observed decline in species diversity under simultaneous N and CO

157 ne is not associated with greater spirometry decline in SZ-AATD, suggesting that cessation attenuates

158 peak pDC frequency, we detected a transient decline in the ability of pDCs to produce IFNalpha in vi

159 is in both water conditions was mainly due a decline in the chlorophyll content (non-stomatal limitat

160 The laparoscopic era brought about a decline in the conventional surgical management of commo

161 ctions, which plays a primary role in memory decline in the early stage of AD.

162 om this facility was associated with a rapid decline in the incidence of L. monocytogenes ST6 infecti

163 lication defects, in part by causing a rapid decline in the level of TUBGCP6.

164 This hypomyelination was accompanied by a decline in the number of myelinating oligodendrocytes an

165 This revealed a decline in the number of residues driving amyloid format

166 bbreviated analysis, also showed a frequency decline in the scarcer southeast Pacific song type n.1 b

167 age-related tauopathy, we compared rates of decline in the sum of boxes score from the CDR(R) Dement

168 The primary outcome was the rate of decline in the total score on the Amyotrophic Lateral Sc

169 The proportion of patients reporting a decline in total cognitive score was similar among the 2

170 s scores at the postworkshop assessment, the decline in total skills scores at delayed assessment (F[

171 4% (95% confidence interval [CI], 9% to 19%) decline in viral load for each additional year in durati

172 cted rhesus macaques, an earlier and sharper decline in viral load was consistently detected for the

173 Furthermore, decline in WC was significantly associated with lower ri

174 In contrast, decline in WC was significantly associated with lower ri

175 and peak body ice content were predicted to decline in Wood Frogs across most of our study region, w

176 Within groups, CV declined in a statistically significant fashion from bas

177 endometrial tissues peaked on day 3 and then declined in all mice with or without deficiency in adapt

178 PCV10-type carriage declined in children <5 years and adults post-PCV10 intr

179 st demersal species in the north central GoM declined in the first few years following DWH, more rece

180 ident acute myocardial infarction (AMI) have declined in the United States, yet disparities by sex re

181 ent coronary heart disease (CHD) events have declined in the United States.

182 The incidence of APSGN has sharply declined in the Western world, whereas the number of Sta

183 The malaria prevalence has declined in western Kenya, resulting in the risk of neur

184 Late-life declines in avian song, and possibly other sexual traits

185 nvironmental conditions were associated with declines in breeding probability at both colonies.

186 uity, characterised by pronounced downstream declines in channel size and local termination.

187 Larger absolute declines in CWS arsenic concentrations at higher water a

188 ely predict which specific stressors lead to declines in different populations or contexts, hindering

189 evolved populations and clones show apparent declines in fitness.

190 ses, acquired pathologies, and aging-related declines in health.

191 longitudinal and circumferential strains and declines in LV ejection fraction and fractional shorteni

192 er snow disappearance, with somewhat smaller declines in meadow soil.

193 und that agricultural intensification led to declines in modularity but increases in nestedness and c

194 ies with exposed anthers experiencing larger declines in ozone displayed more dramatic pigmentation i

195 parabiosis we report that thymic involution, declines in peripheral T-cell counts, and reduced major

196 - and short-DUP patients experienced similar declines in psychosocial function, but declines occurred

197 e global evidence on the drivers of national declines in stunting prevalence and compares the relativ

198 ess whether-and how-humanity can reverse the declines in terrestrial biodiversity caused by habitat c

199 marine phytoplankton, resulting in universal declines in the rate of carbon fixation with short-term

200 Cyclin/Cdk1 activity normally declines in tight association with increasing N/C and is

201 despite the survivorship in both treatments declining in continued exposure to OA.

202 esence and onset of VI, and subsequent VRQoL declines, in these individuals.

203 SCLC declined almost entirely as a result of declining incidence, with no improvement in survival.

204 es constant self-renewal, and its functional decline is a visible consequence of aging.

205 Long-term cognitive decline is an adverse outcome after major surgery associ

206 This study hypothesizes that the functional decline is faster at the edge of the dense scotoma (eMS)

207 olonged period of time with stable, slightly declining levels of disease spread.

208 iciency syndrome, given its slow rate of CD4 decline, low to undetectable viremia, and high neutraliz

209 t the role of viruses in bloom formation and decline may be governed by host physiology rather than b

210 Unique mechanisms of cognitive decline may exist for subgroups of the population, and a

211 looming') events occurring during periods of declining modeled division rates, an observation that hi

212 They declined modestly over the study period, from $133.1 bil

213 that catches from transboundary species are declining more than those from non-transboundary species

214 he effect of smoking cessation on spirometry decline (n = 60) and plasma anti-neutrophil elastase cap

215 DCD DDKT and regional/national imports declined nationwide but most steeply in states with the

216 ing space, which is shrinking as a result of declining natural resources, climate change, and the gro

217 sapiens into Europe coming into contact with declining Neanderthal populations(7,8).

218 milar declines in psychosocial function, but declines occurred at different times relative to first a

219 Recent work has shown that fibrous root decline occurs in HLB-affected trees before symptom deve

220 the home monitoring group (SD = 15.8) and a decline of 0.48 points in the standard care group (SD =

221 I, 13.8-23.8 mo) in patients achieving a PSA decline of at least 50%.

222 istent immune-mediated myocardial damage and decline of cardiac function, likely because of dampened

223 egional eutrophication, respectively, on the decline of coastal coral communities following the devel

224 ative disorder, resulting in the progressive decline of cognitive function in patients.

225 very in adulthood.SIGNIFICANCE STATEMENT The decline of cortical plasticity after closure of juvenile

226 depletion of CD4 T cells, with a progressive decline of host immunity.

227 We argue that this event caused the dramatic decline of the Pearl River estuary coral communities rep

228 photoreceptor death, which eventually led to decline of visual function in older mice between 6 and 1

229 Kansas prairie revealed both 5-y cycles and declines of 2.1-2.7%/y.

230 Accelerating declines of an increasing number of animal populations w

231 cifugus), whose populations have experienced declines of over 90% because of the introduced fungal pa

232 Short-term CNTF treatments caused further declines of photoreceptor transcription factors accompan

233 Declines often appear driven by natural enemies, disease

234 home with social service, and 5) functional decline on discharge, and geriatric risk prediction mode

235 oded by intra-host HBV variants that rapidly decline or persist in presence of TDF.

236 th cognitive function at baseline, cognitive decline or with conversion rates to dementia but high sa

237 y diagnosed acute and chronic HBV infections declined or were stable overall, but increased significa

238 er lower SES is a determinant of the rate of decline over 8 y in six domains-physical capability, sen

239 The decline over time in reported cough was statistically si

240 virus-containing vaccine have been shown to decline over time, but there is no formal recommendation

241 und that people expected their creativity to decline over time.

242 s) present early in HIO differentiation that declines over time in culture.

243 incidence due to vaccine serotypes (VT) has declined, partial replacement by non-vaccine serotypes (

244 individual-eye data and investigated the RPE decline pattern using 3 models: the area linear model (A

245 extending interventions could ameliorate the declining performance of the ejaculate as a whole.

246 y experience multiple stressors and globally declining populations.

247 and therapeutic nuclear medicine procedures declined precipitously, with countries worldwide being a

248 nment of the irrigation network and cultural decline primarily correlate with fluvial entrenchment du

249 ghly dependent on reefs may need to adapt to declining productivity, but further research to support

250 fidence interval, 309 years to infinity) but declined rapidly among HIV-infected participants (half-l

251 but had minor effect on ascorbic acid, which declined rapidly independent of storage temperature.

252 etary support, even though dietary adherence declined rapidly.

253 s and we demonstrate that the benefit of LGT declines rapidly with genome size.

254 We estimated the VA decline rate over 8 years using a linear mixed model.

255 The RPE decline rate was estimated using a 2-stage random-effect

256 the effect of pollution on forest health and decline received much attention in the 1980s, it has not

257 associated with lesser and greater cognitive decline, respectively, from mid- to late life among Blac

258 cal issue in North China with large GW level declines resulting in urban water scarcity, unsustainabl

259 ncreasingly vulnerable to coastal hazards as declining sediment supply and climate change alter their

260 many POPs (PCBs, DDT, HCHs, endosulfan) have declined significantly over the past 10 years, though th

261 icate that spot shrimp populations have been declining significantly over the past 25 years.

262 lated using proportional hazards regression, declined steadily with age at BMI assessment, from 1.25

263 l in the Indo-Pacific region) and seven were declining strongly but with less certainty (mostly repti

264 when analysed separately, three systems were declining strongly with high certainty (all in the Indo-

265 n territory (Italy), causing the Olive Quick Decline Syndrome.

266 y age-related tauopathy has slower cognitive decline than Alzheimer's disease across multiple neurops

267 that females had a 40% higher risk for CD4 + decline than males.

268 ented heat wave in Siberia contribute to the decline that is bound to show catastrophic consequences

269 Unfortunately, due to dramatic declines this fauna is among the most threatened globall

270 eing well with recent model simulations, and declined through the Eocene as global climate cooled.

271 By linking reproductive decline to changing foraging strategies for the first ti

272 CI, -4.1 to -5.2) between 2000 and 2009 and declined to -2.3% (95% CI, -1.2 to -3.4) between 2010 an

273 HCWs testing positive for SARS-CoV-2 rapidly declined to near-zero between 25th April and 24th May 20

274 lity changes that ranged from possible small declines to increases of 5% or less in either sex.

275 s KfSLAC1 and KfALMT12 transcript abundance, declining to near zero by the end of the light period.

276 Average titers peaked on day 7 and declined toward day 14 (P = .004).

277 ed TB incidences demonstrated a continuously declining trend from 75.38/100,000 to 52.25/100,000.

278 This declining trend in the forcing of terrestrial carbon sin

279 3 [95% CI: 69, 97]), followed by significant declining trends from the late 2000s through early 2010s

280 ter time points of white matter and clinical decline using both internal and external datasets.

281 ement for culture-positive eyes was based on declining vision (3 eyes), worsening clinical examinatio

282 This lack of overall increase or decline was consistent across arthropod feeding groups a

283 Interindividual eGFR decline was highly variable but in addition intra-indivi

284 : Across 3 years, FEV(1)% predicted per-year decline was nearly 40% less in those with PA using azith

285 nt effects on lifespan and physical activity decline, which suggests that these age-related traits ca

286 tillers), and branching of the inflorescence decline with a decrease in chlorophyll level.

287 is perhaps associated with normal cognitive decline with age as well as with Alzheimer's disease.

288 ayers, there was a statistically significant decline with age of only the GCL, inner plexiform layer,

289 elated viruses predicted that COVID-19 would decline with higher temperatures, humidity, and ultravio

290 years old conditional survival continued to decline with increasing length of stay.

291 The cost of a viable kidney tended to decline with the number of kidneys procured up to 549 ki

292 Survival often declined with earlier snow disappearance, with somewhat

293 Across all populations, productivity declined with increased precipitation during the fall sp

294 Risk-adjusted mortality declined with increasing discharge delay and was lowest

295 ly and positively correlated with K(OA), but declined with increasing relative humidity.

296 The midpoint of denaturation declined with the removal of repeats.

297 elihood of neurologically favorable survival declines with prolonged resuscitation.

298 inner heliosphere, the electron temperature declines with the distance approximately as [Formula: se

299 Coral reefs are on a steep trajectory of decline, with natural recovery in many areas unlikely.(1

300 in recent years illustrating bee population declines worldwide.