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1 pid metabolic genes, with most genes showing decreased expression.
2 reas transforming growth factor-beta1 caused decreased expression.
3 oters of stem cell genes, resulting in their decreased expression.
4 ctivation of resting T cells resulted in its decreased expression.
5 nover were overrepresented in the genes with decreased expression.
6 g genes showing, respectively, increased and decreased expression.
7 sed vitamin B-12 in liver and cord blood and decreased expression and activity of MS in liver point o
8 Either intravenous or gastric loading led to decreased expression and activity of renal Pi transporte
12 educed H3K36me3 enrichment, concomitant with decreased expression at shared genes which function to m
13 creating gene lists with variably increased/decreased expression compared with steady state/baseline
14 pression is abnormal in psoriatic skin, with decreased expression correlating with recruitment of T-c
16 these clusters included genes with initially decreased expression followed by increased expression at
19 to ischemia and DIO3, MT1G and CMA1 showed a decreased expression in females compared to males due to
20 veral SMALL AUXIN UP RNA (SAUR) genes showed decreased expression in mutant plants defective in these
21 3 snoRNA was one of a number of snoRNAs with decreased expression in osteoarthritic cartilage and ost
22 2 disease risk variants were associated with decreased expression in peripheral and mucosal tissues a
26 apoptosis (IAPs) family member, exhibited a decreased expression level after DHM treatment, which ma
27 We also observed, from a separate study, a decreased expression level of DNA mismatch repair genes
29 ermore, association between inflammation and decreased expression levels of MAGI3, PTEN, and TJP1 in
30 mortem DLPFC expression data analysis showed decreased expression levels of NURR1 and ERR1 in patient
31 classic M1 proinflammatory macrophages) and decreased expression levels of proinflammatory and profi
33 ervations, soluble extracts of PRF membranes decreased expression levels of the osteoclast marker gen
34 ng phenotype of Trem2 R47H knock-in mice was decreased expression levels of Trem2 in microglia, which
36 e ER genome wide-binding pattern, leading to decreased expression of 'classical' oestrogen-regulated
37 ted genes, and we confirm experimentally the decreased expression of 19 microRNAs with 11 correspondi
39 l limitation to relaxin-based IPF therapy is decreased expression of a relaxin receptor, relaxin/insu
40 s a critical imbalance in RAS represented by decreased expression of ACE in combination with increase
42 derailment at this early age is suggested by decreased expression of adiponectin, the fat mass and ob
44 sing antifibrotic effect as indicated by the decreased expression of alpha smooth muscle actin, when
45 ic N-methyl-D-aspartate (NMDA) receptors and decreased expression of alpha-amino-3-hydroxy-5-methylis
46 ophosphamide was sufficient to normalize the decreased expression of alpha-smooth muscle actin in der
47 aginal cell DNA which may be associated with decreased expression of an estrogen-responsive gene.
48 d with OA derived extracellular vesicles had decreased expression of anabolic genes and elevated expr
49 lpha-Klotho in association with enhanced BP, decreased expression of angiotensin converting enzyme 2,
51 sufficient for infection in cell lines with decreased expression of antiviral IFN genes at baseline.
52 osmolality in mice that was associated with decreased expression of aquaporin (AQP)-2 in the renal i
53 A2, overexpression of ZmHSBP2 in Arabidopsis decreased expression of AtGOLS1, AtGOLS2 and AtRS5, decr
59 that the relA knockout strains demonstrated decreased expression of beta-hemolysin/cytolysin, an imp
60 s, androgen deprivation in the medium led to decreased expression of both androgen receptor and its t
61 glycosylation end product (RAGE), exhibited decreased expression of both HMGB1 and MX1 after UVB exp
64 dingly, immunohistochemistry staining showed decreased expression of CARD14 in patients' skin, as wel
68 ts with high sST2, flow cytometry identified decreased expression of CD14 (4.27 x 10(5) +/- 2,950 arb
69 ations have immature CD56(dim) NK cells with decreased expression of CD16, perforin, CD57, and impair
70 tometry to characterize AMs, a significantly decreased expression of CD163, an M2 marker, was seen in
72 ls, T cell subsets from methadone users show decreased expression of CD69 and CD25 in response to TCR
74 (2+) overload, mitochondrial depolarization, decreased expression of cell-cycle genes and reduced tum
75 IgG or phosphate-buffered saline (PBS), had decreased expression of chitin synthetase, CHS1, CHS2, a
79 the phosphorylation of ERK, together with a decreased expression of cleaved caspase-3 in mice treate
80 creased ribosomal content was accompanied by decreased expression of cMYC, a positive regulator of ri
81 of A(2B) adenosine receptors correlated with decreased expression of Col1 and was associated with poo
82 depleted cardiomyocyte secretome resulted in decreased expression of collagen I and III in fibroblast
83 In vitro cultures of synthetic VSMCs showed decreased expression of contractile markers CNN-1 (calpo
85 itory factors CTLA-4, PD-1, and Blimp-1, and decreased expression of costimulatory molecules CD40L, C
88 These differences were due to significantly decreased expression of crtOPQMN and aur Previous studie
89 BXD2-p19(-/-) GC B cells was associated with decreased expression of CSR-related novel base excision
90 (Tcm), evidence of Type I polarization, and decreased expression of CTLA-4 and PD-1 in BAL Tregs, su
94 l cell-specific NRP1 knockout mice exhibited decreased expression of DDAH1 and slightly increased exp
96 Infection with NiggV but not NiggA led to decreased expression of Dicer and Ago 2, suggesting that
101 defective LTbetaR signaling correlated with decreased expression of endothelial and angiogenic marke
102 nd differentiation pathways, suggesting that decreased expression of EPB41L4A is a mechanism in the p
105 ting enhanced cytolytic activity, as well as decreased expression of exhaustion markers in CD4(+) and
106 on of proteolysis in endothelial cells, with decreased expression of extracellular matrix remodeling-
107 id not affect lifespan, and was coupled with decreased expression of extracellular signal-regulated k
108 s downregulated in HCC patient specimens and decreased expression of FBP1 associated with poor progno
109 monstrated by reduced collagen abundance and decreased expression of fibronectin-1, collagen I, alpha
110 chors mGluR5 to the cell surface, as well as decreased expression of FKBP5, implicating aberrant gluc
111 educing sensory glutamate release results in decreased expression of GABA-synthesizing enzymes GAD65
114 T(reg) cells deficient in complex III showed decreased expression of genes associated with T(reg) fun
115 a transcriptomic signature characterized by decreased expression of genes critical for mitochondrial
116 Impaired differentiation was associated with decreased expression of genes encoding critical hematopo
118 nscriptional regulators TCF4 and NEUROD6 and decreased expression of genes involved in long-term pote
121 essing CD38 and ICOS and was associated with decreased expression of genes that regulate cell-cycle a
122 eta, ERK 1/2, NF-kappaBp65, and NF-kappaBp50 decreased expression of GLUT4 mRNA were observed in the
124 ference silencing of GmMYB29A2 increased and decreased expression of GmNAC42-1, GmMYB29A1, and glyceo
125 MENT-BINDING2A mutant (zmdreb2a) lines, with decreased expression of GRETCHEN HAGEN3.2 (ZmGH3.2, enco
126 higher fasting insulinemia, concomitant with decreased expression of hepatic gluconeogenic genes.
127 osis, and the antiangiogenic factor GAX, and decreased expression of HIF-1alpha and proangiogenic fac
129 eased protein expression of MUC16, SIRPA and decreased expression of HLA-DRB1 was further demonstrate
130 s, reduced colony-forming activity in vitro, decreased expression of Hox genes in the hematopoietic s
131 TDF also increased expression of GFAP and decreased expression of IBA1 in the wt and gp120-tg mice
132 on, as TICAM2 deficient neutrophils have the decreased expression of ICAM1, CD11b, PD-L1, and the red
134 BIIB059 administration in patients with SLE decreased expression of IFN response genes in blood, nor
135 R274W mice was associated with paradoxically decreased expression of IFN-stimulated genes (ISGs) and
137 ence of nuclear translocation of RelA with a decreased expression of IL-6, IL-12p40, and IL-17A.
138 ortant for iNKT17 differentiation, including decreased expression of IL-7Ralpha, BATF and c-Maf and i
140 Here we report that CTA was associated with decreased expression of immediate early genes in rat GC
143 monstrated improved urine output (P = .009), decreased expression of injury biomarker NGAL (P = .012)
144 levant neuropeptides in the hypothalamus and decreased expression of insulin receptor signaling genes
145 ormality; however, VHR-knockout cells showed decreased expression of integrins and FAK but stronger F
147 ssive antibiotic therapy was associated with decreased expression of interleukin-2 high-affinity rece
148 mic inflammation, nutrient malabsorption and decreased expression of intestinal and pancreatic genes
149 r effects through inhibition of lipogenesis; decreased expression of invasion associated proteins thr
152 d a profound loss of tissue differentiation, decreased expression of keratin 4 (KRT4) and cornulin (C
153 Furthermore, residual Rora(sg/sg) ILC3s have decreased expression of key signature genes, including R
156 o and JEG3 cells under hypoxia significantly decreased expression of LIN28B and LIN28A, SYN-1, and EL
157 ctivation and increased granulocytes; and 4) decreased expression of lymphocyte related genes and lym
158 blood samples, while nasal samples also had decreased expression of many genes associated with cilia
161 ltage-gated potassium channel gene Kcna1 and decreased expression of metabotropic glutamate receptor
166 In the brains of wt and gp120-tg mice, TDF decreased expression of mitochondrial transcription fact
167 elates with impaired DNA mismatch repair and decreased expression of Mlh1 and Msh2 genes, defects fre
169 sd10 and Acaa2, and blunted VLDL export with decreased expression of Mttp and its product microsomal
170 ere also associated with either increased or decreased expression of multiple additional classes of t
171 unding the cuticle of the abdomen results in decreased expression of multiple HSR genes in proximal a
173 ockdown resulted in increased E-cadherin and decreased expression of N-cadherin and snail transcripti
174 netic variants in NBEAL1 are associated with decreased expression of NBEAL1 in arteries and increased
175 iology associated with neuroinflammation and decreased expression of neuronal activity marker, which
176 ear factor-kappaB (NF-kappaB) activation and decreased expression of NF-kappaB target genes matrix me
177 genetic inhibition of sestrin 2 resulted in decreased expression of NKG2D and DAP12 and restored TCR
178 ardiomyocyte-related genes, and simultaneous decreased expression of nodal cardiomyocyte-related gene
179 ultiple sclerosis that were characterized by decreased expression of NRF2 and increased expression of
180 We found that constitutive NIK expression decreased expression of numerous Treg signature genes an
182 ed optic nerve pathological states, we found decreased expression of one major metalloproteinase prot
185 ns This increase in survival correlated with decreased expression of pattern recognition receptors on
188 against melanoma in a syngeneic model, with decreased expression of PD-L1 and of matrix metallo-prot
189 -4-hydroxy-5-methoxyphenyl)methane (Cl-OCH3) decreased expression of PD-L1 mRNA, promoter-dependent l
191 mural cells, an effect that associated with decreased expression of PDGFRbeta and p57kip2, a cyclin-
195 dominal aortic aneurysms and correlated with decreased expression of predicted miR-181b targets, tiss
196 t under glucose deprivation (GD) conditions, decreased expression of presenilin 1 (PS1) results in de
197 en of the striatum of xCT(-/-) mice revealed decreased expression of presynaptic proteins and abnorma
198 ith elevated expression of osteogenic genes, decreased expression of pro-inflammatory cytokine genes,
199 induces NEFM, RET, and VACHT and results in decreased expression of proapototic (BMF, BIM), adrenerg
201 D8(+) T cells with an effector phenotype and decreased expression of programmed death receptor-1 (PD-
203 This enhanced adhesion was associated with decreased expression of protein kinase A regulatory subu
204 thione (GSH) was upregulated in chRCC due to decreased expression of proteins involved in GSH degrada
205 and DNA replication and damage repair, and a decreased expression of proteins responsible for core ex
206 ture silencing of Ptch1 These cells also had decreased expression of Pten, which encodes a negative r
207 blocks primitive hematopoiesis, as shown by decreased expression of pu.1, mpo, and l-plastin; and di
209 ssues of HFD-fed UtxAKO female mice revealed decreased expression of rate-limiting enzymes of triacyl
210 nslates into reduced histone lactylation and decreased expression of reparative macrophage genes.
211 ocalization and decrease in visual pigments, decreased expression of retinoic acid-responsive genes a
215 rc, coding for stereocilin, and dramatically decreased expression of Rps4l, coding for a ribosome sub
216 ngevity pathways exhibit small nucleoli, and decreased expression of rRNA, ribosomal proteins, and th
217 ells (definitive hematopoiesis), as shown by decreased expression of runx1 and c-myb However, adtrp1
218 ld-type at 29 degrees C, suggesting that the decreased expression of SAUR genes is partly responsible
219 in differentiating neural cells we observed decreased expression of schizophrenia-associated gene Fe
221 ts with OA undergoing total knee replacement decreased expression of senescent and inflammatory marke
222 portant stimuli for TNFalpha expression, and decreased expression of several M2 markers, including in
224 sed expression of VLDLR, as well as 1.5-fold decreased expression of SMARCA2, located 388 kb away.
225 blocked the activation of primary HSCs, with decreased expression of smoothened, GLI2 and ILK compare
226 ted substantial activation of p53 and STAT3, decreased expression of SOCS7, and increase in profibrot
228 Uterine tumor epithelium was associated with decreased expression of steroid biosynthesis genes, incr
229 luteinizing hormone/testosterone ratio, and decreased expression of steroidogenic mRNAs, appropriate
232 and Bifidobacterium-colonized mice exhibited decreased expression of synapse-promoting genes and incr
233 terferon-gamma, and fractalkine as well as a decreased expression of synaptophysin, a neuronal activi
238 sverse aortic constriction, corresponding to decreased expression of the angiogenic factor VEGF.
239 ed inflammation under high-SS conditions and decreased expression of the antiinflammatory factor KLF-
240 l BA, colonocytes from WD-fed mice exhibited decreased expression of the BA transporters FABP6, OSTbe
242 rliest signaling alterations in CRC, and the decreased expression of the bile acid apical transporter
243 mponent protein expression, they demonstrate decreased expression of the calcium-dependent protein ki
244 d spread of bacteria in infected leaves, and decreased expression of the central defense gene TaNPR1
245 tumors have elevated T cell infiltrates and decreased expression of the CLEC2D receptor, which may p
246 ity associated with infection sites, and had decreased expression of the early auxin responsive gene
247 pressive Tregs in the injured myocardium and decreased expression of the gene encoding IFN-gamma, a k
249 specification of hemangioblasts, as shown by decreased expression of the hemangioblast markers, etsrp
250 n mice is cell intrinsic and associated with decreased expression of the high affinity IL-2 receptor
251 of the IL23 subunits IL23p19 and IL12p40 but decreased expression of the IL12 subunit IL12p35 in cerv
252 ed expression of proinflammatory factors and decreased expression of the immunosuppressive cytokine I
253 nic hepatitis C virus (HCV) infection causes decreased expression of the iron hormone hepcidin, which
254 ression of the iron exporter ferroportin and decreased expression of the iron importer transferrin re
256 s and microglial accumulation accompanied by decreased expression of the LPC receptor G2A, whereas MS
257 aternal PolyI:C exposure was associated with decreased expression of the maternally imprinted genes M
258 The increase in PP2A activity is caused by decreased expression of the MID1 ubiquitin ligase that m
260 morphine tolerant mice, contributing to the decreased expression of the mouse and human MOR-1B3 and
262 normal human diploid fibroblasts results in decreased expression of the mTOR inhibitor DDIT4 (REDD1)
263 city to use glycolysis, a function linked to decreased expression of the NAD(+)-dependent protein dea
264 xpression of the anti-oxidant marker CAT and decreased expression of the pro-oxidant marker NOX-4.
265 more complete inhibition of p-S6, leading to decreased expression of the pro-survival protein MCL-1,
268 ng in cystinosis was found to associate with decreased expression of the small GTPase Rab11 and the R
269 pecific proteins, rhodopsin and cone opsins, decreased expression of the specific inflammatory marker
270 miscarriage is associated with significantly decreased expression of the T-cell co-receptor CD8 and t
271 terations in this group are likely driven by decreased expression of the transcription factor FOXM1 a
273 ds to rapid cell de-differentiation, without decreased expression of the transcription factors NKX2-1
278 for pulmonary endothelial HIF-2alpha and how decreased expression of this endogenous factor causes em
282 how that Treg cells in food allergy (FA) had decreased expression of transforming growth factor beta
283 d with promoter hypermethylation, leading to decreased expression of tumor suppressor genes, as well
284 giogenic factor thrombospondin 1 (Tsp-1) and decreased expression of two critical pro-angiogenic fact
285 d activation of microglia and astrocytes and decreased expression of tyrosine hydroxylase in periglom
286 lotting analyses showed that MEOX1 knockdown decreased expression of tyrosine kinase 2 (TYK2), signal
287 zed by decreased energy expenditure (EE) and decreased expression of uncoupling protein 1 (UCP1) in b
288 S promoters, enhanced ICAM-1 expression, and decreased expression of upstream regulators of KLF2 (ERK
290 revealed a decreased copy number of UT2 and decreased expression of UT2 in genomic and transcriptomi
291 idenced by a reduced clinical disease score, decreased expression of various inflammatory cytokines,
293 pression of E-cadherin and beta-catenin, and decreased expression of vimentin and snail, which is par
294 ction, GYY4137 treatment was associated with decreased expression of viral proteins and mRNA, suggest
295 nes showed 1.2-fold significantly (P < 0.04) decreased expression of VLDLR, as well as 1.5-fold decre
299 ite branches and total neurite length, and a decreased expression on RhoA and neurodegenerative prote