ライフサイエンスコーパス: defecation

1 "shrinker" movement , abnormal foraging and defecation .

2 by biofeedback therapy (such as dyssynergic defecation).

3 continence, anorectal pain, and disorders of defecation).

4 ynx) to seconds (gonadal sheath) to minutes (defecation).

5 nction (anal incontinence (AI) and difficult defecation)].

6 s higher in those reporting pain relief with defecation.

7 m signaling is central to the periodicity of defecation.

8 etermined that miR-786 functions to regulate defecation.

9 2 activity is the likely mechanistic link to defecation.

10 large bowel include storage, propulsion and defecation.

11 colonic contractile activity and CRF-induced defecation.

12 ansit time, constipation and difficulty with defecation.

13 pain that is accompanied by a disturbance in defecation.

14 ns of the posterior body wall muscles during defecation.

15 es a G(s)alpha signaling pathway to regulate defecation.

16 ified by proton influx from the lumen during defecation.

17 wall muscle contraction (pBoc) required for defecation.

18 ional freezing, ultrasonic vocalization, and defecation.

19 educating patients to avoid straining during defecation.

20 t modify baseline myoelectrical activity and defecation.

21 training, as measured by freezing, USV, and defecation.

22 s, grimacing, teeth gnashing, urination, and defecation.

23 anal sphincter must be studied to understand defecation.

24 tress responses, including self-grooming and defecation.

25 hild's face, and to always use a latrine for defecation.

26 iber and water and avoiding straining during defecation.

27 e abdominal pain and changes associated with defecation.

28 tory of lumbar and perineal pain and painful defecation.

29 r (IAS-SMCs) abolishes basal tone, impairing defecation.

30 in global [Ca(2+)]i and impairs the tone and defecation.

31 Over 1 billion people still practice open defecation.

32 ies to build their own toilets and stop open defecation.

33 cles to preserve fecal continence and enable defecation.

34 IHLs and even more modest reductions in open defecation.

35 ho still have no option but to practice open defecation.

36 sanitation, and 59% for dependence upon open defecation.

37 The primary outcome was time to defecation.

38 %), maternal nutrition (19.3%), reduced open defecation (12.3%), maternal and newborn health care (11

39 r of health workers (28%), reduction in open defecation (13%), parental education (10%), maternal nut

40 tions per week (8/17, 47%), straining during defecation (7/19, 37%) and lumpy or hard stools (6/19, 3

41 ported symptoms were a feeling of obstructed defecation (8/19, 42%), <3 defecations per week (8/17, 4

42 g (24%), nausea (16%), frequent small-volume defecation (9%), increased frequency of micturition (9%)

43 Moreover, defecation activity was hardly analyzed by previous stud

44 f handwashing with soap at key events (after defecation, after cleaning a child's bottom, before food

45 rol versus 41% intervention), decreased open defecation among adults by an average of 10% (95% CI for

46 The presentation of painful defecation, anal fissures, and macroscopic blood in stoo

47 t the end of the study, 58.2% practiced open defecation and 25.7% experienced APOs, including 130 (19

48 CRF and urocortin elicited defecation and a new pattern of ceco-colonic clustered s

49 wo-thirds of the 1.1 billion practising open defecation and a quarter of the 1.5 million who die annu

50 hoods to promote handwashing with soap after defecation and before preparing food, eating, and feedin

51 rolapsing hemorrhoids may partially obstruct defecation and cause soilage from the passage of fecal m

52 so identified specific effects on open-field defecation and center avoidance and distinguished them f

53 rs that are capable of performing studies of defecation and colonic transit.

54 argely on understanding the motor control of defecation and continence mechanisms.

55 ominopelvic-rectoanal coordination in normal defecation and DDs is poorly characterized.

56 gut attachment prevents parasite loss during defecation and determines vector competence.

57 In this cross-sectional study the Groningen Defecation and Fecal Continence questionnaire was comple

58 It includes two subtypes; dyssynergic defecation and inadequate defecatory propulsion.

59 ients with a functioning pouch, frequency of defecation and incidence of incontinence, and the patien

60 giene and sanitation behaviors (such as open defecation and mouthing of soil contaminated materials),

61 n General Scale, reflecting attitudes toward defecation and norms regarding latrine use for all respo

62 Mean weight of each defecation and stool moisture did not increase and serum

63 ow that intestinal pH also oscillates during defecation and that transepithelial proton movement is e

64 are likely the result of contamination from defecation and urination atop guano and which reflect th

65 ain referred to the perianal region, painful defecation and weight loss have predictive value for loc

66 e regression analysis perianal pain, painful defecation and weight loss were significantly associated

67 nophils) is associated with pain relief with defecation and with anxiety and depression in youth with

68 study suggest that with increasing time post-defecation and with the onset of challenging environment

69 the expression of conditioned freezing, USV, defecation, and analgesia were significantly impaired by

70 t between the lumen and the cytoplasm during defecation, and extends the defecation period.

71 gesia, 22 kHz ultrasonic vocalization (USV), defecation, and freezing.

72 ons also blocked stress-induced freezing and defecation, and greatly attenuated adrenocortical activa

73 oms largely are unrelated to food intake and defecation, and it has higher comorbidity with psychiatr

74 he nematode Caenorhabditis elegans: feeding, defecation, and ovulation.

75 ols pelvic functions, including micturition, defecation, and penile erection, as well as to brain net

76 fiber intake, avoidance of straining during defecation, and phlebotonics.

77 rons that are involved in movement, feeding, defecation, and reproduction.

78 nal pain, abdominal distension, frequency of defecation, and stool characteristics, and could relieve

79 The mean St Mark's score, ability to defer defecation, and the number of incontinent episodes per w

80 n of E. coli growth within dairy faeces post defecation; and (ii) derive E. coli seasonal population

81 Most physicians consider infrequency of defecation as a hallmark of constipation.

82 The decrease in open defecation associated with teacher-facilitated CLTS was

83 t symptom was 'manual maneuver to facilitate defecation' at 23.3%.

84 ric nervous system (ENS) control feeding and defecation behavior, respectively.

85 nal pacemaker during the rhythmic C. elegans defecation behavior.

86 respectively, to sustain normal feeding and defecation behavior.

87 (PVT) that we implicate here in controlling defecation behavior.

88 the larval anal depressor muscle is used for defecation behavior.

89 ity of individual household latrines (IHLs), defecation behaviors, and child health (diarrhea, highly

90 ported outcomes for diarrhea, HCGI, and open defecation behaviors.

91 Subsidies also reduced open defecation by 14 percentage points (P < 0.001).

92 ogram that seeks to end the practice of open defecation by changing social norms and behaviors, and p

93 ssible method to evoke colon contraction and defecation by microstimulation of the S2 spinal cord wit

94 Fluoxetine decreased stress-induced defecation (by 60%), reversed the stress-induced suppres

95 icroRNA cluster, which results in arrhythmic defecation, causes ectopic intestinal calcium-wave initi

96 cting its muscle arm from the neurons of the defecation circuit.

97 tabases and search terms: bowel dysfunction, defecation, constipation and irrigation.

98 included consumption of river water and open defecation; consumption of reverse osmosis-treated water

99 levels oscillate with the same period as the defecation cycle and peak calcium levels immediately pre

100 In addition, ovulation and the defecation cycle are abnormal and arrhythmic.

101 Overall, these results establish the defecation cycle as a model system for studying transepi

102 mediates sphincter muscle contraction in the defecation cycle in hermaphrodites, and spicule eversion

103 The C. elegans defecation cycle is characterized by the contraction of

104 Pharyngeal pumping, the defecation cycle, and gonadal-sheath-cell contractions a

105 tion, the timing of an ultradian rhythm, the defecation cycle, is lengthened compared to wild type.

106 tinal epithelial cells regulate the nematode defecation cycle.

107 ansient in the GABAergic neurons during each defecation cycle.

108 , a fatty-acid elongase with a known role in defecation cycling, as a direct target for miR-786.

109 Dyssynergic defecation (DD) is defined as paradoxical contraction or

110 orrhoids, chronic anal fissures, dyssynergic defecation (DD), and fecal incontinence (FI), which are

111 aphy, which are used to diagnose dyssynergic defecation (DD), are performed asynchronously and in dif

112 Open defecation decreased by 15.3 percentage points overall b

113 h rates of fecal incontinence and obstructed defecation decreased significantly (P < 0.0001) after LV

114 ratio [OR]=0.81 [95% CI 0.76-0.86]) and open defecation decreased them by 18% (OR=0.82 [0.76-0.88]).

115 nterestingly, aex-6 mutants exhibit the same defecation defect as aex-3 mutants.

116 re synaptic transmission defect as well as a defecation defect not seen in rab-3 mutants.

117 athway in GABAergic neurons can suppress the defecation defect of the intestinal mutants aex-4 and ae

118 cy to enter an open quadrant, open time, and defecation, demonstrating that genetic factors mediate a

119 A defecation disorder (DD) is a difficulty in evacuation d

120 ndrome (SRUS) is an uncommon although benign defecation disorder.

121 om the use of drugs such as opioids, or from defecation disorders and advanced colonic dysmotility.

122 lable laxatives focuses on the importance of defecation disorders and biofeedback therapies.

123 Functional defecation disorders are characterized by 2 or more symp

124 Functional defecation disorders are defined by >2 symptoms of chron

125 ese observations demonstrate that functional defecation disorders comprise a heterogeneous entity tha

126 I), functional anorectal pain and functional defecation disorders.

127 ollowing TME is accompanied by postoperative defecation dysfunctions known as "anterior resection syn

128 tainable Development Goals: eliminating open defecation, expanding capacity-building, and strengtheni

129 nteric muscles (as evident from the rates of defecation failure) and also with altered sensitivity to

130 r larger studies to better understand normal defecation, feces-withholding patterns, and the implicat

131 mproved voluntary control of micturition and defecation for patients with neurogenic bladder overacti

132 with the goal of declaring communities open defecation free.

133 t the achievement and sustainability of open-defecation-free (ODF) status in Cambodia, Ghana, Liberia

134 fects of probiotics compared with control on defecation frequency (n = 965) or treatment success (n =

135 5; P = .06), which correlated inversely with defecation frequency (r = -0.3; P = .10).

136 ics did not confer any beneficial effects on defecation frequency (WMD: -0.55 BMs/wk; 95% CI: -1.37,

137 mpared with placebo or treatment as usual on defecation frequency [bowel movements (BMs)/wk] or treat

138 n, probiotics did not significantly increase defecation frequency [weighted mean difference (WMD): 0.

139 The first fiber addition increased defecation frequency and decreased fecal pH, bile acid c

140 strointestinal and colon transit, as well as defecation frequency and water content, in wild-type, kn

141 dietary fiber do not change transit time or defecation frequency if they are already approximately 1

142 Defecation frequency in the combined group of patients w

143 core was 5 (range 0-8, n = 6), with a median defecation frequency of 3 (range 1-8/day).

144 Defecation frequency was reduced 2.6-fold in tgr5-ko and

145 of CRF(2) (urocortin 2) reduced CRF-induced defecation (>50%), colonic contractile activity, and Fos

146 ntomological research, its obligate partner, defecation, has been comparatively neglected.

147 ith > or =2 of the following features during defecation: impaired evacuation, inappropriate contracti

148 Median ability to defer defecation improved from seconds preoperatively to 10 mi

149 s, rectal sensation, and ability to withhold defecation improved with age to levels comparable to con

150 omplete evacuation (%), and straining during defecation (%) improved from 17 +/- 3.2 to 10 +/- 4.5, 9

151 erminants of stunting, reduced rates of open defecation, improved sanitation infrastructure, and impr

152 ts reveal distinct dynamics of urination and defecation in a test-, strain-, and sex-dependent manner

153 sulted in a similar pattern and magnitude of defecation in both strains.

154 n humans and an ultradian rhythm controlling defecation in Caenorhabditis elegans.

155 65 (20 mg/kg s.c.) significantly reduced the defecation in response to water avoidance stress but not

156 umption of surface phytoplankton followed by defecation in the deep ocean.

157 e in the probability of engaging in any open defecation in the last 7 days, respectively.

158 diagrams and to provide comparative data on defecation indices (DIs) between passive and urge incont

159 type mice using still manometry; we analyzed defecation induced by acute partial-restraint stress (PR

160 ocomotion, pharyngeal pumping frequency, and defecation interval time.

161 In C. elegans, defecation is an ultradian rhythmic behavior: every appr

162 BACKGROUND & AIMS: Disordered defecation is attributed to pelvic floor dyssynergia.

163 Disordered defecation is attributed to pelvic floor dyssynergia.

164 Although obstructed defecation is generally attributed to pelvic floor dyssy

165 CLTS is most appropriate where open defecation is high because there were no significant cha

166 ticularly in countries like India where open defecation is highly prevalent.

167 In C. elegans, rhythmic defecation is timed by oscillatory Ca(2+) signaling in t

168 nt frequency, and difficulty with the act of defecation itself with excessive straining and incomplet

169 s modulated during sleep-pharyngeal pumping, defecation, locomotion, head movement, and avoidance res

170 Functional disorders of defecation may be amenable to pelvic floor retraining by

171 foraging, ecological interactions involving defecation may have far-reaching evolutionary consequenc

172 hat calcineurin is required for the rhythmic defecation motor program (DMP) in C. elegans.

173 The Caenorhabditis elegans defecation motor program (DMP) is a highly coordinated r

174 During the defecation motor program in C. elegans, calcium oscillat

175 In the defecation motor program of Caenorhabditis elegans, a pa

176 the posterior intestinal cells triggers the defecation motor program that comprises three sequential

177 During the C. elegans defecation motor program the posterior body muscles cont

178 gnaling and in the intestine to regulate the defecation motor program.

179 three muscle contractions that comprise the defecation motor program.

180 al access to health services and reduce open defecation; multisectoral poverty reduction strategies;

181 nd 40% prevalence across Indian states, open defecation (OD) remains high despite India's investments

182 roach to improving sanitation to combat open defecation (OD).

183 present the first evidence of ingestion and defecation of physically or chemically dispersed crude o

184 95% CI 0.29-0.98), as was handwashing after defecation (OR 0.47, 95% CI 0.24-0.90).

185 nd a 19.9 percentage point reduction in open defecation (p < 0.001).

186 lood loss, pain, prolapse, and problems with defecation (P < 0.05).

187 to the posterior cells that function as the defecation pacemaker.

188 ucing in intestinal peristalsis and abnormal defecation parameters including the frequency of pellet

189 ed stool named Fecobionics to study distinct defecation patterns in FI patients using preload-afterlo

190 v.) or 1 h water avoidance stress stimulated defecation (pellet/60 min: 4.1+/-1.0 and 8.7+/-0.7 respe

191 ing of obstructed defecation (8/19, 42%), <3 defecations per week (8/17, 47%), straining during defec

192 subcharacterized by perineal descent during defecation, perineal location at rest, and anal resting

193 cytoplasm during defecation, and extends the defecation period.

194 tary intake (AOR 3.0, 95% CI 1.2, 7.3), open defecation practice (AOR 3.0, 95% CI 1.2, 7.9), presence

195 core were significantly associated with open defecation practice, mouthing of soil contaminated mater

196 terials (AOR 2.31, 95% CI (1.26, 4.24), open defecation practices (AOR 2.22, 95% CI (1.20, 4.10), lim

197 potential sources of contamination were open defecation practices, unhygienic disposal of wastes, poo

198 und to be significantly associated with open defecation practices.

199 During the preparatory phase of defecation, rectal and anal pressures increased concurre

200 rs had lower anal diameters during simulated defecation, rectal pressure, anorectal junction descent,

201 ayer, which provides primary micturition and defecation regulation, and the transversus layer, which

202 cted intracisternally antagonized partly the defecation response in Lewis and Fischer rats.

203 her residual anal pressures during simulated defecation, resulting in significantly more negative rec

204 hholding of feces because of fear of painful defecation, results in constipation and overflow soiling

205 These mutants also have an altered defecation rhythm (Dec).

206 2+ oscillations that regulate the C. elegans defecation rhythm.

207 The primary endpoint was time to first defecation; secondary outcomes were morbidity, other ile

208 re of tolerance of solid food and having had defecation (SF + D) (area under the curve = 0.9, SE = 0.

209 sepithelial proton movement is essential for defecation signaling.

210 orted pre-operative symptoms were obstructed defecation syndrome (ODS) in 40%, fecal incontinence (FI

211 syndrome (PPS) in patients with obstructive defecation syndrome (ODS).

212 continence in 22%, combination of obstructed defecation syndrome and fecal incontinence in 21% and ot

213 ported preoperative symptoms were obstructed defecation syndrome in 40%, fecal incontinence in 22%, c

214 ved electroacupuncture had a shorter time to defecation than patients who received no acupuncture (85

215 lectroacupuncture also had a shorter time to defecation than patients who received sham acupuncture (

216 a participatory approach to addressing open defecation that has demonstrated success in previous stu

217 rate both pH and calcium signals to regulate defecation timing.

218 ng, unsafe disposal of fecal waste from open-defecation to nearby drinking water sources severely end

219 Practicing open defecation was a risk factor for MSD in children <5 y ol

220 erall but did not change where baseline open defecation was below 30%.

221 The association between APOs and open defecation was independent of poverty and caste.

222 Defecation was initiated by abdominal wall expansion tha

223 Time to defecation was longer with open surgery compared with la

224 ices or latrine upgrades where baseline open defecation was low.

225 Stress-induced defecation was reduced by 52% in Lewis compared with Fis

226 [35%] of 1911 households) and reported open defecation was reduced in female (198 [9%] of 2086 vs 60

227 tention-to-treat analysis, the time to first defecation was significantly shorter in the enteral nutr

228 socio-demographic and clinical factors, open defecation was still significantly associated with incre

229 drinking-water supply, sanitation, and open defecation were abstracted from 138 national surveys und

230 Blood oxygen saturation, locomotion, and defecation were measured to evaluate side effects.

231 Most patients, dependent on laxatives for defecation, were able to generate normal motor patterns

232 Other IP(3)-mediated processes, e.g., defecation, were unaffected.

233 elaxation of the pelvic floor muscles during defecation, which causes functional constipation.

234 tal colonic motor function (bead transit and defecation) while oCRF(9-33)OH (devoid of CRF receptor a

235 ere less exploratory and had higher rates of defecation with strain-dependent effects on activity lev

236 sociation of poor sanitation practices (open defecation) with these outcomes is independent of povert

237 coli population in the immediate period post defecation, with most E. coli activity (as either die-of

238 ed with the number of people practicing open defecation within 50 m and the sheep population for Cryp

239 Coprimary outcomes were laxation (defecation) within 4 hours after the first dose of the s