ライフサイエンスコーパス: defense against

1 These cells provide defense against a daily assault by airborne bacteria, vi

2 Oral mucosa provides the first line of defense against a diverse array of environmental and mic

3 CRISPR functions as a long-term memory-based defense against a diverse landscape of viral species, we

4 oleucine were enhanced in the mutant, as was defense against a lepidopteran herbivore.

5 e responses, IgE antibodies, and MCs in host defense against a pathogenic bacterium.

6 deaminases constitutes a vital innate immune defense against a range of different viruses.

7 a therefore implicate CIITA and CD74 in host defense against a range of viruses, and they identify an

8 n factor, mediate innate and adaptive immune defense against a variety of viral infections.

9 tigated the IL-1 family member IL-33 in lung defense against A. fumigatus IL-33 was detected in the n

10 nvestigation of previously understudied host defenses against a major crop plant pathogen.

11 hydrogen sulfide (H(2) S) that provides some defense against antibiotics.

12 nfer inceptin-induced responses and enhanced defense against armyworms (Spodoptera exigua) in tobacco

13 iew, we first discuss novel concepts in host defense against Aspergillus infections and emphasize new

14 ry genes in response to HFD as an endogenous defense against atherosclerosis in ApoE(-/-) model.

15 ted the mechanistic basis of this endogenous defense against atherosclerosis.

16 sine editing may also represent an important defense against autoimmune diseases such as MS.

17 Amphibians have complex and varied immune defenses against B. dendrobatidis, but the fungus also h

18 hat human NK cells also contribute to immune defense against bacteria through recognition of a conser

19 Therefore, although providing host defense against bacteria, PC:CRP-induced inflammation ma

20 response is a central element of the initial defense against bacterial and viral pathogens.

21 ivity, but the participation of PTEN in host defense against bacterial infection is less well underst

22 regulation of macrophage Nrp1 in host immune defense against bacterial infection remain unknown.

23 whether IL-17D has a role in mediating host defense against bacterial infections, we studied i.p. in

24 studies reveal a novel role of mast cells in defense against bacterial infections.

25 e serum complement system is a first line of defense against bacterial invaders.

26 ic multiprotein complexes that initiate host defense against bacterial pathogens by activating caspas

27 ese genes in nonhost resistance and stomatal defense against bacterial pathogens, respectively.

28 tericidal activities and is pivotal for host defense against bacterial pathogens.

29 lymphoid cells (ILC3s) are critical for lung defense against bacterial pneumonia in the neonatal peri

30 inase-I.9), was shown to contribute to plant defense against bacterial, oomycete, and fungal pathogen

31 as systems provide prokaryotes with adaptive defense against bacteriophage infections.

32 ible bacteria by acting as the first line of defense against beta-lactam antibiotics, and antibiotic

33 with respect to growth and morphogenesis and defense against biotic and abiotic stress.

34 l functions, such as in hormone transport or defense against biotic and abiotic stresses.

35 revealing a trade-off between metabolism and defense against biotic stress.

36 enormous diversity of compounds as chemical defenses against biotic and abiotic insults.

37 red the role of platelets in antifungal host defense against C. albicans PBMCs were stimulated with h

38 L-17A produced by gammadelta T cells in host defense against C. difficile infection.

39 nal, providing a variety of weapons for self-defense against cancer-targeted therapy.

40 obial peptides that are the ultimate line of defense against carbapenem-resistant pathogens in clinic

41 sensitive client proteins in a first line of defense against cellular stress.

42 Yet, T cell-mediated inflammation and host defense against Citrobacter rodentium were not impaired

43 sted Mp708 plants, indicating BX-independent defense against CLA.

44 n many recent advances in understanding host defenses against common fungi, this work illuminates not

45 ocalizations, parental care of eggs, or nest defense against cuckolders.

46 e of Gram-negative bacteria functions in the defense against cytotoxic substances, such as antibiotic

47 s still unclear how xylem contributes to the defense against DED.

48 1 (RPW8.1) activates confined cell death and defense against different pathogens.

49 tralizing antibodies also function as a main defense against disease establishment in a host.

50 In contrast, TLR7 was important for defense against disease in the lungs.

51 mune system with the aim of bolstering plant defenses against disease.

52 id cells are, beside as the first barrier of defense against diseases, an excellent model system to i

53 ol of lysosome function broadly impacts host defense against diverse viral and microbial pathogens.

54 evolutionarily conserved function of Toll in defense against DNA viruses.

55 -the enabling of gas exchange, and the first defense against drought-this trade-off constrains the ra

56 to define nonredundant requirements for host defense against EBV infection.

57 e results suggest the importance of CH25H in defense against education of normal cells by TEV and arg

58 epithelium plays fundamental roles in immune defenses against enteric viral infections by integrating

59 how ILC3 are involved in LCN-2-mediated host defense against Enterobacteriaceae.

60 innate and adaptive immunity leading to host defense against enteropathogenic bacterial infection.

61 t intestinal inflammation and establish host defense against enteropathogens.

62 Brown adipocytes provide a metabolic defense against environmental cold but become dormant as

63 the first line of physical and immunological defense against environmental insults.

64 drial respiration but also controls cellular defense against ER and oxidative stress.

65 an essential role of Rif1 in the epigenetic defense against ERV activation.

66 However, the role of small RNAs in defense against eukaryotic pathogens is unclear.

67 entify a critical role for caspase-8 in host defense against eukaryotic pathogens.

68 unctions to induce a broad range of cellular defenses against exogenous and endogenous stresses, incl

69 ation by commensal C. albicans improves host defense against extracellular pathogens, but with potent

70 lites, was important for maize seedling root defense against F. graminearum.

71 umoral immunity may provide vital first-line defense against fatal outcomes in case of an A(H7N9) pan

72 hboring plants, they are able to prime their defenses against feeding insects.

73 -3-ols (catechin and proanthocyanidins) as a defense against foliar rust fungi, but the regulation of

74 tion of plant growth and modulation of plant defenses against foliar pathogens Botrytis cinerea and P

75 transfer from bacteria possibly function in defense against foreign DNA or viruses.

76 In addition to defense against foreign DNA, the CRISPR-Cas9 system of F

77 n or CRISPR-Cas systems as part of an innate defense against foreign DNA.

78 Bacteria possess an array of defenses against foreign invaders, including a broadly d

79 fibrin degradation, thwarts T cell-mediated defense against fully virulent Y. pestis Introducing a s

80 ammatory response by macrophages during host defense against fungal challenge.

81 rbohydrate beta-1,3-glucan, is vital to host defense against fungal infections.

82 Furthermore, mechanisms regulating host defense against fungal pathogens remain elusive.

83 s unclear whether Gsr is required for immune defense against fungal pathogens.

84 ed NF-kappaB could profoundly influence host defense against fungal pathogens.

85 nigmatic cytokine IL-17F contributes to host defense against fungi.

86 Additionally, the critical host defenses against gammaherpesvirus reactivation, virus-sp

87 e to infer the molecular mechanisms of plant defense against GB, little is known about the effect of

88 gene silencing (TGS) is a natural antiviral defense against geminiviruses.

89 Antagonism of host immune defenses against hepatitis B virus (HBV) infection by th

90 Age-dependent changes in plant defense against herbivores are widespread, but why these

91 A well-known trade-off exists between plant defenses against herbivores and defenses against pathoge

92 her they also function as generalized direct defenses against herbivores and pathogens remains unknow

93 ecific metabolites that function as indirect defenses against herbivores of the wild tobacco Nicotian

94 against phytopathogens, but may also aid in defense against herbivorous beetles.

95 ell wall modification, thus triggering plant defenses against herbivory.

96 biological pathways have been implicated in defense against Hessian fly.

97 nisms of antibiotic resistance and bacterial defense against host immunity; however, there is little

98 The vaginal epithelium is the first line of defense against HSV-2 and coordinates the immune respons

99 Astrocytes are a primary defense against hyperexcitability, but their functional

100 blood glucose concentrations compromises the defense against hypoglycemia, a common complication in d

101 ionally seen as the first and most important defense against hypoglycemia.

102 Host defense against IA relies on lung-infiltrating neutrophi

103 Innate immunity provides an immediate defense against infection after host cells sense danger

104 T cells provide immune-surveillance and host defense against infection and cancer.

105 It represents the first line of defense against infection and is involved in tissue repa

106 roducing gammadelta T cells in neonatal host defense against infection and provide a mechanistic expl

107 Neutrophils act as the body's first line of defense against infection and respond to diverse inflamm

108 e innate immune system is essential for host defense against infection and tissue homeostasis.

109 ler (NK) cells, which are implicated in host defense against infection with herpesviruses, including

110 lular traps (NETs) are important in the host defense against infection, but they also promote intrava

111 responses toward pathogens are essential for defense against infection.

112 ic acid sensors as one of the first lines of defense against infection.

113 ce suggests they have multiple roles in host defense against infection.

114 lay a crucial role in the regulation of host defense against infection.

115 Host defenses against infection by this pathogen are poorly u

116 f immune cells is a vital cornerstone of our defense against infections and a key challenge of immuno

117 Collectively, PTI contributes to host defense against infections by a broad range of pathogens

118 lving MyD88 or STING constitute a first-line defense against infections mainly through production of

119 ells that provide the first line of cellular defense against infections or injuries.

120 the host, including immunity, inflammation, defense against infections, and metabolism.

121 ovel role for GPER activation in skin innate defense against infectious disease suggests that G-1 may

122 n-coupled estrogen receptor (GPER) to innate defense against infectious disease, particularly with re

123 onocytes and macrophages, is a first line of defense against infectious diseases and plays a key role

124 suppress the host innate and acquired immune defenses against infestations.

125 optosis) and plays an essential role in host defense against influenza A virus (IAV) infection.

126 dicate that exposure to dry air impairs host defense against influenza infection, reduces tissue repa

127 dings demonstrate that the initial intrinsic defense against influenza is mediated by platelet-neutro

128 significant insight into this first line of defense against influenza virus infection and provide a

129 iary beating, is the primary physical airway defense against inhaled pathogens and irritants.

130 ins unknown whether plants can amplify their defenses against insect eggs by responding to cues indic

131 the hypothesis that a plant strengthens its defenses against insect eggs by responding to insect sex

132 It is not clear how LACC1 balances defenses against intestinal bacteria vs intestinal infla

133 ascertain whether IL-26 contributes to host defense against intracellular bacteria, we studied lepro

134 the Th17 cytokine IL-26 contributes to host defense against intracellular bacteria.

135 ly activated" phenotype that participates in defense against intracellular pathogens.

136 rophils represent the first line of cellular defense against invading microorganism by rapidly moving

137 immune sensors of DNA are essential for host defense against invading pathogens.

138 ukocytes in humans and are essential for the defense against invading pathogens.

139 ssociated molecular patterns to promote host defense against invading pathogens.

140 ages (Mphi) are critical for the coordinated defense against invading S. aureus, yet they have a limi

141 nt system is a crucial part of innate immune defenses against invading pathogens.

142 nal epithelial autophagy is crucial for host defense against invasive pathogens, and defects in this

143 ing, suggesting that Toll mediates antiviral defense against Kallithea virus infection but that it is

144 ism by which L-selectin participates in host defense against Klebsiella pneumoniae-induced pulmonary

145 ive cytokines play an important role in host defense against L. pneumophila infection.

146 , cell types known to be important for early defenses against L. monocytogenes in the spleen, as well

147 ubiquinone acts as the cell's first line of defense against LCFA-induced oxidative stress.

148 intestinal microbiota provides nonredundant defense against lethal, disseminated infection.

149 PFKP), pentose phosphate pathway (G6PD), and defense against lipid peroxidation (GPX4) scored high as

150 ally prevent cells from mounting an adequate defense against lipid peroxidation and thereby promote f

151 -MLKL pathway in nonimmune cell-derived host defense against Listeria invasion, which is mediated thr

152 esponse to IL-12 and for an efficient immune defense against Listeria monocytogenes Deletion of TYK2

153 ion of intracellular peptidoglycans and host defenses against Listeria monocytogenes.

154 hether such AwM play a critical role in host defense against M. tuberculosis infection.

155 ntional and innate-like T (iT) cells in host defenses against M. marinum remain unclear.

156 NK) cells are important players in the early defense against many viral infections, the NK cell respo

157 d oxidative stress, estrogenic activity, and defense against metals.

158 l and pathological processes, including host defense against microbial infections, anti-tumor immunit

159 spase-11 (caspase-1/-4/-5/-11)) mediate host defense against microbial infections, processing pro-inf

160 ial role in regulating inflammation and host defense against microorganisms in the intestine.

161 represents the immune system's first line of defense against mucosal pathogens.

162 hin the mucosa are part of the first line of defense against mucosal pathogens.

163 l that GBP2 is an important mediator of host defenses against murine norovirus.

164 ssity of l-citrulline metabolism for myeloid defense against mycobacterial infection and highlight th

165 t for activation of immune cells during host defense against Mycobacterium tuberculosis.

166 gated the role of plant toxins in nectar for defense against nectar robbers [4, 9, 10].

167 In contrast, their role in defense against nonviral pathogens is more ambiguous.

168 g cassette (ABC) transporter plays a role in defense against numerous pathogens and is recruited to s

169 ing of white adipose tissue (WAT) provides a defense against obesity.

170 In many bacteria, defense against OG depends on MutT enzymes, which saniti

171 spond to these VOC cues by priming their own defenses against oncoming herbivory, thereby reducing fu

172 bility to store H2S in vivo and as a line of defense against oxidative stress, from which it is clear

173 pathway, which provides a critical cellular defense against oxidative stress.

174 regulation, pain signaling, and cancer cell defense against oxidative stress.

175 ased expression of tpx, a gene essential for defense against oxidative stress.

176 play between the nuclear lamina and cellular defenses against oxidative DNA damage, with implications

177 idant enzymes, gut cell renewal as potential defenses against oxidative injuries and the profile of m

178 33c's activity was consistent with a role in defenses against oxidative stress generated during host

179 age-FABP4 has a novel role in pulmonary host defense against P. aeruginosa infection by facilitating

180 ffects of the propolis envelope as a natural defense against Paenibacillus larvae, the causative agen

181 ype 2 immunity, allergic reactions, and host defense against parasite infections.

182 Anthelmintic drugs are the major line of defense against parasitic nematode infections, but the a

183 stinal mucous layer provides a critical host defense against pathogen exposure and epithelial injury,

184 Defense against pathogen insult (often reliant upon host

185 ostatic skin barrier functions and providing defense against pathogen intrusion.

186 are phagocytes that serve as a first line of defense against pathogenic insults to tissues.

187 Skin provides the first defense against pathogenic micro-organisms and is also c

188 ng in growth and reproduction, as well as in defense against pathogenic microbes.

189 icrobial activity, presumed to contribute in defense against pathogenic microorganisms as plants with

190 ptive immunity genes that contribute to host defense against pathogenic viruses such as herpes viruse

191 of our digestive tract is the first line of defense against pathogens and damage.

192 methylase 2) family protein, which modulates defense against pathogens and flowering time.

193 n the control of cell-signaling pathways and defense against pathogens and whose imbalance leads to p

194 AIM2 plays essential roles not only in host defense against pathogens but also in inflammatory disea

195 cells (LCs) in the skin are a first line of defense against pathogens but also play an essential rol

196 al killer (NK) cells are critical for innate defense against pathogens through direct cytotoxicity of

197 gammat for development and contribute to the defense against pathogens through IL-22 and IL-17 secret

198 een shown to be involved in the constitutive defense against pathogens through the secretion of toxic

199 repertoire development, to provide lifelong defense against pathogens while maintaining self-toleran

200 luding tissue development and repair, innate defense against pathogens, and generation of adaptive im

201 h as the regulation of endogenous processes, defense against pathogens, and response to abiotic stres

202 masome activation is critical for the host's defense against pathogens, but dysregulation of inflamma

203 nate immune system acts as the first line of defense against pathogens, including coronaviruses (CoVs

204 nce of peptidoglycan N-deacetylation on host defense against pathogens, we investigated the virulence

205 is, necroptosis) is an integral part of host defense against pathogens.

206 patterning, photoassimilate distribution and defense against pathogens.

207 ommunities that can act as the first-line of defense against pathogens.

208 but they also play an important role in host defense against pathogens.

209 s) participate in allergy, inflammation, and defense against pathogens.

210 une systems in animals and plants as natural defense against pathogens.

211 microbial peptides (AMPs) as a first line of defense against pathogens.

212 ntibodies provide an efficient first-line of defense against pathogens.

213 adaptive response that ensures an efficient defense against pathogens.

214 e of the circadian clock in regulating plant defense against pathogens.

215 Programmed cell death contributes to host defense against pathogens.

216 mmatory response is necessary for the host's defense against pathogens; however, uncontrolled or unre

217 Mast cells (MCs) are involved in host defenses against pathogens and inflammation.

218 development and provides insights into host defenses against pathogens and the immunological mechani

219 Host defenses against pathogens are energetically expensive,

220 optosis is a form of cell death important in defenses against pathogens that can also result in a pot

221 etween plant defenses against herbivores and defenses against pathogens, but few studies incorporate

222 -1Ra) has emerged as a pivotal player in the defense against periodontitis.

223 ilized effector molecule that can operate in defense against persistent infection at times when other

224 , less soil biodiversity, and inferior plant defense against pests.

225 , it is unclear whether CCA1 plays a role in defense against phloem sap-feeding aphids.

226 They play a crucial role in plant defense against phytopathogens by inhibiting microbial p

227 tial roles for fibrin during T cell-mediated defense against Pla-mutant Y. pestis Moreover, the effic

228 s to thwart fibrin-dependent T cell-mediated defense against plague.

229 ucan and signal at Fcgamma receptors enhance defense against Pneumocystis f. sp. murina, though it is

230 ights the role of CD28 costimulation in host defense against poxvirus infections.

231 -gated sodium (Na(v)) channels as a chemical defense against predation.

232 Chemical defense against predators is widespread in natural ecosy

233 sHsps act as the first line of cellular defense against protein unfolding stress.

234 ne memory contributes to the protective host defense against recurring MRSA infection.

235 tissue-resident memory T cells (TRM) in the defense against recurring pathogens and malignant neopla

236 ivo Macrophages are a critical first line of defense against respiratory pathogens.

237 primed innate immune system is an effective defense against retroviral pathogenesis, resulting in re

238 estriction factors provide the first line of defense against retrovirus infection by posing several b

239 vital pathogen recognition receptors in the defense against RNA viruses.

240 Abscisic acid also promoted poplar defense against rust infection, but likely through stoma

241 to subvert macrophage-mediated innate immune defense against S. aureus biofilms.

242 ypothesis that platelets participate in host defense against S. aureus both through direct killing of

243 ty of mouse platelets to participate in host defense against S. aureus infection was determined by as

244 y pathway consisting of human monocyte-based defense against S. aureus suggests that targeting the NK

245 entify novel host factors important for host defense against S. aureus.

246 physicians and enhance understanding of host defense against SARS-CoV-2.

247 ls are induced by pathogens and promote host defense against secondary infections.

248 fection substantially improved systemic host defense against secondary SA infections in mice.

249 memory cells were required for optimal host defense against skin VV infection.

250 Sex bias in innate defense against Staphylococcus aureus skin and soft tiss

251 Adipose tissue provides a defense against starvation and environmental cold.

252 vement of Jonah66Ci in the Drosophila immune defense against Steinernema carpocapsae nematode infecti

253 Defense against stress and active suppression of growth

254 ncoded by NFE2L2, is the master regulator of defense against stress in mammalian cells.

255 f a single allele of A20 results in enhanced defense against systemic Candida albicans infection and

256 esponses in vivo and is a suppressor of host defense against systemic fungal infection.

257 t nociceptor neurons critically mediate host defense against the bacterial pathogen Salmonella enteri

258 ay protective and regulatory roles in immune defense against the opportunistic mold Aspergillus fumig

259 ybean) Sec4 functions in the root during its defense against the parasitic nematode Heterodera glycin

260 vices personnel are a critical first line of defense against the spread of COVID-19.

261 attack their hosts and how the hosts mount a defense against the threats.

262 these cells upon infection are critical for defense against the virus, and therefore, it is importan

263 nfection sites is a fundamental step in host defenses against the frequent human pathogen group B Str

264 ry disease is able to promote antiviral host defenses against the influenza virus.

265 The main line of cellular defense against these electrophilic molecules is conjuga

266 acteriophages, and have evolved a variety of defenses against these invaders.

267 onic acid and salicylic acid to control host defense against this pathogen.

268 the Fv3 infection strategies and the immune defense against this pathogen.

269 matory monocytes (iMO) are critical for host defense against toxoplasmosis and malaria but their role

270 ranscription factor complex to aid in genome defense against transposons.

271 ired for selective autophagy of Mtb and host defense against tuberculosis infection.

272 iller (NK) cells are important in the immune defense against tumor cells and pathogens, and they regu

273 The melanin pigment is a critical defense against ultraviolet radiation (UVR), and its pro

274 Nase 7 has a role in kidney and bladder host defense against UPEC and establish a foundation for inve

275 odulation, augmentation of the Cu-based host defense against UTI represents a novel approach to limit

276 nd topically applied DHA potentiate cellular defense against UVB-induced skin inflammation and photoc

277 RTANCE Innate immune signaling is a critical defense against viral infection and represents a central

278 necroptosis, has been implicated in the host defense against viral infection primary in immune cells.

279 g molecules that are often the first line of defense against viral infection.

280 l cues for proper type 1 ILC homeostasis and defense against viral infection.

281 at detect dsRNA stimulate IFN responses as a defense against viral infection.

282 NK cells are responsible for defense against viral infections and cancer.

283 The first line of defense against viral infections is the innate immune re

284 (IFN-alpha and -beta) are important for host defense against viral infections.

285 The innate immune response is crucial for defense against viral infections.

286 ons (IFNs) play a central role in the immune defense against viral infections.

287 ng the p53 and pRB pathways, or disrupt host defenses against viral infections, including interferon

288 activity and are important mediators of host defenses against viral infections.

289 te immune system, contributing to first-line defenses against viral, bacterial, and fungal pathogens.

290 NK cells provide a defense against virally infected cells using a variety o

291 The interferon system is the first line of defense against virus infection.

292 Type I IFNs are key mediators of immune defense against viruses and bacteria.

293 (NK) cells have an important role in immune defense against viruses and cancer.

294 tive immune systems provide prokaryotes with defense against viruses by degradation of specific invad

295 its prokaryotic host with an adaptive immune defense against viruses that have been previously encoun

296 ntrinsic immunity is known to be a frontline defense against viruses through host anti-viral restrict

297 terferons (IFNs) represent an important host defense against viruses.

298 genes that have evolved to provide intrinsic defense against viruses.

299 thway is dedicated to TE somatic control and defense against viruses.

300 s on the horizon, we risk losing our primary defense against widespread morbidity and mortality from