ライフサイエンスコーパス: definitively

1 the role were more likely to manage the call definitively.

2 without a threshold, but has not been shown definitively.

3 r AAV transduction remains to be established definitively.

4 whose importance has not yet been determined definitively.

5 assign the putative Na(+) and H(+) transport definitively.

6 achomatis conjunctivitis should be diagnosed definitively.

7 , the study is not powered to address safety definitively.

8 re, stroke, and diabetes mellitus though not definitively.

9 m apoptotic and necrotic cells instantly and definitively.

10 st researchers to approach this problem more definitively.

11 the role of innate immunity for clearing HCV definitively.

12 ld be needed to mechanistically link the two definitively.

13 r linked help, but has not been demonstrated definitively.

14 enzymes (ADH1B, ALDH2) have been replicated definitively.

15 although more work is required to show this definitively.

16 that might potentially answer this question definitively.

17 cific binding sites have not been identified definitively.

18 ling in prostate cancer has not been defined definitively.

19 c theories, but one cannot conclude anything definitively about the shape of those theories from any

20 ing consistency, but no mechanism has yet to definitively account for this sex difference.

21 In summary, LIN28B can definitively act as an oncogene in the absence of canoni

22 knockout mouse model (C2KO) designed to more definitively address questions of sAC expression, and we

23 To definitively address the role of Runx1 in CBFB-MYH11-ind

24 prospective studies should be undertaken to definitively address the role of TCD in HCT.

25 A randomized trial is needed to definitively address this question.

26 Existing studies, however, do not definitively address whether suidice attempers have 1) i

27 tumor initiation or maintenance has not been definitively addressed.

28 he 1990s; the data also suggest (albeit less definitively) an increase in winter CO2 emissions, espec

29 erve as a tool for identifying waste sources definitively, analyzing population diversity, and conduc

30 s was performed on patients who were treated definitively and underwent post-treatment PET imaging pe

31 dequately powered trial would be required to definitively assess the efficacy and safety of this appr

32 ve not performed quantum state tomography to definitively assess the teleportation fidelity, our data

33 Prolonged follow-up is warranted to definitively assess their risk of developing second canc

34 pain-2 activities in mouse brain, which more definitively assesses the role of these ubiquitous prote

35 ific environment, it has been challenging to definitively assign adaptive functions to specific mtDNA

36 tion of the newly created chiral centers was definitively assigned for all the corresponding compound

37 3) ambiguous VDPVs (aVDPVs), which cannot be definitively assigned to either of the first 2 categorie

38 Of those, nine were definitively assigned to S. jamesii based on possession

39 There were 12 of 24 syndromic genes definitively associated with isolated left ventricular h

40 solated from these koalas, KoRV has not been definitively associated with leukemogenesis.

41 f patients had an undifferentiated death not definitively attributable to a single cause (981, 59%),

42 estral in land plants cannot yet be answered definitively based on existing data.

43 , no single change in the gut microbiota has definitively been identified as a risk factor or cause o

44 or MRI, in patients at high risk of HCC, as definitively benign, probably benign, intermediate proba

45 implants, direct comparisons cannot be made definitively between implant types, and future investiga

46 we cannot, with available data, discriminate definitively between the effect of true peer effects and

47 We identified definitively bivalent nucleosomes with concomitant repre

48 r all clinically relevant pneumococci can be definitively categorized into distinct serotypes.

49 nscript models produced by CLS enabled us to definitively characterize the genomic features of lncRNA

50 or controlling acute infection have not been definitively characterized.

51 pposed to other aspects of song has not been definitively characterized.

52 About one-third of the OTUs could not be definitively classified at a similarity level of 80%, su

53 10%), insufficient evidence was available to definitively classify reason for presentation.

54 Abdomens were definitively closed downrange (11%), at Landstuhl Region

55 d trial with long-term outcomes is needed to definitively compare the effectiveness of these 2 revasc

56 hes with multiple human cell sources, we can definitively conclude that CpG methylation is absent in

57 rmation of B. pertussis infection, we cannot definitively conclude that pertussis disease is well con

58 ity of high-quality data, it is difficult to definitively conclude which agent is better or what trea

59 milarity with that of MxiC from Shigella, we definitively confirm CopN as the Chlamydia homolog of th

60 and experimental studies have been unable to definitively confirm or disprove this observation.

61 e and noninvasive hemodynamic assessments to definitively confirm or refute the diagnosis of HFpEF.

62 Although it has not yet been definitively confirmed as an independent risk factor for

63 e IPF remains unclear, limited data exist to definitively connect abnormal imaging findings to IPF, a

64 d cytotoxic mediators and have been shown to definitively contribute to asthma.

65 paired rod-like double helical fibers-can be definitively correlated with infectivity, allowed a dire

66 This mutant definitively correlates the 2-5 bp deletions observed in

67 promyelocytic leukemia (APL) patients can be definitively cured by the combination of two targeted th

68 Oral administration of azithromycin definitively decreases the diversity of the gut microbio

69 Taken together, these data definitively define Ikaros as a critical regulator at th

70 atients without JAK2 mutations, has not been definitively delineated.

71 We also could not definitively demonstrate between-group differences in me

72 We thus definitively demonstrate stereopsis in mantises and also

73 These studies definitively demonstrate the first known function of C3

74 Conclusion: The authors could not definitively demonstrate whether the addition of 2 years

75 The authors could not definitively demonstrate whether the addition of 2 years

76 We definitively demonstrate, using genetic mouse models, th

77 tence and neuropathogenesis but has not been definitively demonstrated in an animal model of HIV-indu

78 ity produced non-enzymatically have not been definitively demonstrated to mediate any known disease p

79 This study definitively demonstrates that autoimmune demyelinating

80 Mutational analysis definitively demonstrates that TbPRMT1(ENZ) is the cofac

81 The structure definitively demonstrates the ring orients during transl

82 Still, definitively demonstrating the human benefits of isolate

83 us is a murine roseolovirus (MRV), the first definitively described rodent roseolovirus, to our knowl

84 Only a rostral forelimb area (RFA) has been definitively described, besides few reports of a rostral

85 at over 100 carbon-bearing species have been definitively detected in the interstellar medium via the

86 tional nature, meaning that we are unable to definitively determine causality.

87 These findings require replication to definitively determine clinical utility of this treatmen

88 rge clinical trial data are required to more definitively determine CTO revascularization guidelines.

89 Longer-term studies are needed to definitively determine the effect of bougie size on weig

90 full phylogenetic tree would be required to definitively determine the effect of genetic evolution o

91 diagnosed in the 1970s makes it difficult to definitively determine the effect of risk factors on lat

92 and a randomized clinical trial is needed to definitively determine the impact of penicillin prophyla

93 ement, additional study is warranted to more definitively determine the optimal methods to detect pre

94 andomized clinical trials, is needed to more definitively determine the role of statin therapy in old

95 controlled, randomized studies are needed to definitively determine their role in the treatment of my

96 Further study is needed to definitively determine whether cocoa significantly impro

97 ed, placebo-controlled efficacy trial (1) to definitively determine whether prevention of CMV reactiv

98 cance of these findings will need to be more definitively determined in future Phase 3 studies.

99 cleotide affects polymerization remain to be definitively determined.

100 ns of the glutamatergic input have yet to be definitively determined.

101 f the 4 dengue virus serotypes remains to be definitively determined.

102 s controlling its biosynthesis have not been definitively determined.

103 egative for AQP4-Abs and may be difficult to definitively diagnose.

104 Of these 8 patients, 2 were definitively diagnosed as having TINU syndrome (confirme

105 e disorder affecting movement and cognition, definitively diagnosed only at autopsy.

106 evaluations, while CTE currently only can be definitively diagnosed postmortem.

107 spectively studied 317 patients who had been definitively diagnosed with NS.

108 are 4 times after illness onset before being definitively diagnosed with trichinellosis.

109 clinically active targeted therapeutics can definitively discriminate driver from passenger lesions

110 well understood because no method exists to definitively distinguish regenerated from preexisting my

111 Because isotopic patterns cannot definitively distinguish these alternatives, we pursued

112 etry, we show that these two populations are definitively distinguishable by phenotype in retina.

113 However, DTV has only been definitively documented in 6 patients by molecular analy

114 ng after percutaneous revascularization were definitively due to cardiac causes, with an even smaller

115 of the 1953 operation could not be assessed definitively during H.M.'s life.

116 nctional epicardial substrates, which may be definitively eliminated by radiofrequency ablation, rema

117 ed by the amount of information available to definitively elucidate the molecular formula of a molecu

118 s), accurately measure clonal complexity, or definitively elucidate the order of mutations.

119 gh the pathological mechanisms have not been definitively elucidated, evidence suggests a key role fo

120 rmation of a case of Ebola virus disease, we definitively enumerated on a list a ring (cluster) of al

121 y useful human cell lines, we used TALENs to definitively eradicate LEDGF/p75 by deleting either all

122 Efforts to definitively establish a similar stem cell hierarchy wit

123 demonstrated that Titmus stereoacuity cannot definitively establish normal VA, and therefore can sugg

124 These data definitively establish that complete structural integrit

125 ternal Cdx2 using a Cre/lox strategy, and we definitively establish that maternal Cdx2 is not essenti

126 To definitively establish the functional role of PERK in ad

127 However, further studies will be required to definitively establish the identity of the causative gen

128 Further studies are needed to definitively establish the mechanisms by which G6PD defi

129 provided sufficient clinical information to definitively establish the presence or absence of glauco

130 ess analyses using observational data cannot definitively establish the superiority of one technique

131 ed, controlled trials are urgently needed to definitively establish their potential for smoking cessa

132 comes of chemotherapy-treated adults are not definitively established and should be evaluated.

133 link between RABV and human disease has been definitively established and the extent to which RABV ut

134 is, thermotaxis, and rheotaxis have not been definitively established in mammals.

135 orbiting such a pair of normal stars was not definitively established until the discovery of the plan

136 he reducing equivalents in vivo has not been definitively established, but a cyanobacterial [2Fe-2S]

137 trioid endometrial cancer (EEC) has not been definitively established.

138 of increased risk with omalizumab cannot be definitively established.

139 The pathogenicity of norovirus is definitively established.

140 mitochondrial location of mHTT has not been definitively established.

141 failure in normal sinus rhythm has not been definitively established.

142 the central nervous system have rarely been definitively established.

143 This work definitively establishes the differential effector funct

144 remained residual CD28-dependent responses, definitively establishing that additional motifs can par

145 d state of the Fe(II)-based photosensitizer, definitively establishing that Fe(II) polypyridyl comple

146 editing is potentially an important tool for definitively establishing the functional roles of indivi

147 cells at levels similar to those of V exons, definitively establishing the V exon location as "privil

148 To definitively evaluate dual TCRalpha cells, we generated

149 individual blood cell lineages has not been definitively evaluated.

150 d N-terminal antibodies, allowing us to more definitively examine the role of Shank3 in synaptic func

151 identified, and further study is required to definitively exclude potential benefit or potential harm

152 DNAm change, larger studies are required to definitively exclude this possibility.

153 le to determine whether service use outcomes definitively excluded mental health treatment.

154 rventions occurring simultaneously cannot be definitively excluded.

155 To definitively explore the potential for clinical efficacy

156 rotein characterization, showing that AI-ETD definitively extends the m/z range over which ETD can be

157 Half of readmissions were definitively for new infections, whereas an additional 3

158 e randomized controlled trials are needed to definitively guide the clinical use of probiotics in out

159 avior in soils, enantiopure (-)-beflubutamid definitively has the potential to substitute for the rac

160 probability of being HCC, probably HCC, and definitively HCC (corresponding to LI-RADS categories 1-

161 Doppler ultrasound definitively helps to diagnose the tumor thrombus, the e

162 etic makeup of Europeans now shows even more definitively how false those notions are.

163 The definitively identified ("canonical") residues that are

164 ines in a long-term snow-addition experiment definitively identified increasing late-summer dryness a

165 to arginine and lysine variants of PAI-1 and definitively identified the binding site as composed of

166 ent signaling, although no receptor has been definitively identified yet.

167 ne-spanning OMPs of B. burgdorferi have been definitively identified, and none are well characterized

168 an antigen or autoantigen that has yet to be definitively identified, reducing the activity of intrin

169 all effect, a handful of which have now been definitively identified.

170 at is, the signaling mechanism-have not been definitively identified.

171 tified, but direct Fru targets have not been definitively identified.

172 n(s) of theca progenitor cells have not been definitively identified.

173 on, these solution dimers have recently been definitively identified.

174 y (OPAT) at hospital discharge have not been definitively identified.

175 (s) responsible for this event have not been definitively identified.

176 restricted until causal factors can be more definitively identified.

177 dentified while one metabolite, taurine, was definitively identified.

178 tality for which causal agents have not been definitively identified.

179 The patient's infection source was not definitively identified.

180 Ultimately, we were able to definitively identify 3 proteins as putatively metastabl

181 hese instruments have never been utilized to definitively identify aerosolized microbes in ambient se

182 othelial nuclei and membranes we are able to definitively identify and study the morphology and behav

183 that very large samples will be required to definitively identify individual rare variants or genes

184 phene, and necessitates direct HH imaging to definitively identify its atomic structure.

185 e interface (BMI) experiments where we could definitively identify neural firing patterns as output-n

186 To definitively identify regenerated myelin, we used a tran

187 terminal hydroxyl groups) of PS molecules to definitively identify species.

188 To definitively identify the channel, we use whole-mitoplas

189 Validated antibodies are used to definitively identify the most highly expressing cell li

190 h patients, but liver biopsy is necessary to definitively identify those at risk for liver disease pr

191 elves may bring their own data to the table, definitively identifying clinically significant genomic

192 further mechanistic studies are required to definitively illustrate cause and effect.

193 estions remain even after a genomic locus is definitively implicated, including the nature of the cau

194 y a limited number of genetic loci have been definitively implicated.

195 al HMB during fasting periods of TRF did not definitively improve outcomes.

196 (2) If so, do these definitively improve outcomes?

197 xic chemotherapy such as ifosfamide have not definitively improved the survival of patients with oste

198 juries were more likely to have been treated definitively in United States Medical Treatment Faciliti

199 reclinical animal studies of these nutrients definitively influenced the design and interpretation of

200 ibility of unmeasured confounding, we cannot definitively interpret these results as causal.

201 To definitively investigate how these components affect the

202 adverse cardiac events (MACE) have not been definitively investigated.

203 It is not yet definitively known whether dynamic features of head circ

204 he primary reservoir sites in humans are not definitively known, but analysis of murine models has id

205 ness of therapy in this patient group is not definitively known.

206 Here, we definitively link cytotoxicity associated with SOD1 aggr

207 odels has prevented studies which would more definitively link these viral infections to disease.

208 of pancreatic ductal adenocarcinoma (PDA) is definitively linked to activating mutations in the KRAS

209 ense variants in APOL1 (G1 and G2) have been definitively linked to CKD in black Americans.

210 , no lysine acetyltransferase (KAT) has been definitively localized to this organelle to date.

211 Although we cannot definitively locate all of the atoms inside the nanopart

212 ed, we need a precise genetic null mutant to definitively map its amorphic phenotypes.

213 ic compounds were detected, but they are not definitively martian in origin.

214 tency shorter than 1.2 ms were classified as definitively monosynaptic; these were seen only after st

215 While AMA1 is definitively not an essential protein for tachyzoite ent

216 erature magnetic field effects have not been definitively observed in either single-walled carbon nan

217 ime, a unique convective mode not previously definitively observed in the Solar System.

218 y thermal fracture processes have never been definitively observed on an airless body, or any surface

219 s in which such topological states have been definitively observed(6,12-14).

220 trate that driver mutations occurring in MDS definitively occur in cells with a stem cell phenotype.

221 urce for the chlorinated hydrocarbons is not definitively of martian origin.

222 ENT Neurodegenerative diseases are diagnosed definitively only in postmortem brains by the presence o

223 evaluating intronic sequence when a single, definitively pathogenic variant is identified during dia

224 The family is definitively placed in Elateroidea, and we hypothesize i

225 MRI, or gadoxetate-enhanced MRI could not be definitively preferred for HCC diagnosis in patients wit

226 Here, we definitively probe the role of OG handling systems in my

227 hen incorrect, then correct again though not definitively) proposal and Woodward's assignment of the

228 The authors definitively prove that the initiation of cell polarizat

229 tamin B12 is the only nutritional deficiency definitively proved to cause optic neuropathy and loss o

230 sistance of these interventions has not been definitively proved.

231 Cytokine inhibitors have definitively proven a critical role for tumour necrosis

232 Final structures of five scaffolds have been definitively proven by X-ray crystallography.

233 e of the treatments tested to date have been definitively proven to improve survival.

234 CD implantation, its usefulness has not been definitively proven.

235 east a small net benefit, but stops short of definitively recommending that this cohort be screened.

236 rganic matter (DOM) obstructs our ability to definitively recover source compounds from within DOM, a

237 Phylogenetic analysis definitively recovers the species as an abelisauroid the

238 on mortality in trials of interventions that definitively reduced CKD endpoints.

239 To more definitively resolve this question, we generated acute m

240 esis of the anchoring elements have not been definitively resolved.

241 and formation of these structures remain not definitively resolved.

242 f GJ 1214b at near-infrared wavelengths that definitively resolves this ambiguity.

243 However, no gag and gp41-CD mutations definitively responsible for reduced PI susceptibility h

244 Corroborating ab initio calculations definitively rule out a dominant contribution of image c

245 These studies definitively rule out a role for all conserved consensus

246 The results obtained definitively rule out a simple bimolecular nucleation me

247 nistration in situations where rabies can be definitively ruled out.

248 ure and its immunohistochemical features can definitively separate canaliculops from conjunctival cys

249 Implicitly, data also definitively settle a currently unsolved issue on the ca

250 The results also definitively show that distraction is detrimental to dri

251 Here we definitively show that substantial quantities of trypano

252 Affymetrix canine microarray, we are able to definitively show that there are significant differences

253 In addition, we definitively show the atomic-scale distribution of phosp

254 y a better choice than effective absorbance) definitively show there are at least three distinct mole

255 NT FINDINGS: Clinical trials in CKD have not definitively shown that setting a BP target that is lowe

256 , post-transplantation survival has not been definitively shown to be less than average in patients w

257 ase in the hazard of disappearance cannot be definitively shown to have been caused by an increase in

258 ndom walk, however, no detailed analysis has definitively shown whether T cell movement is consistent

259 irus to immune privileged sites has not been definitively shown.

260 This paper definitively shows that an identified cerebral ganglion

261 Our present study definitively shows that RNAi is an important modulator o

262 rd (239 [35%] of 707) of open fractures were definitively stabilised later than 24 h.

263 se Ki67 and PEPI triage approaches are being definitively studied in the ALTERNATE trial.

264 As researchers plan clinical trials to more definitively study whether statins indeed protect agains

265 ower-law nor exponential function provides a definitively superior fit to the modeled profiles.

266 ndomized controlled clinical trials exist to definitively support the efficacy of surveillance progra

267 ing transport where high-field MR saturation definitively supports spin polarization instead of a mor

268 AMG900 is a promising opportunity to definitively test the clinical benefit of dual Aurora ki

269 eved with our intervention, are indicated to definitively test this potentially safe and inexpensive

270 s for the need for large phase III trials to definitively test this question.

271 This trial was designed to definitively test whether calcium/magnesium decreases ox

272 confined to the tips of the thalli and show definitively that a lack of structural colour elsewhere

273 cebo-controlled randomised trials have shown definitively that almost all of the symptomatic adverse

274 Our data demonstrate definitively that both H1R and H2R participate in the im

275 the USA who have led the field have asserted definitively that CTE is a delayed-onset and progressive

276 letion virus that lacks the H5 gene and show definitively that genome synthesis does not occur in the

277 Further, this work demonstrates definitively that mouse collecting lymphatic vessels exh

278 Here we demonstrate definitively that neurons from native neural networks wi

279 -affinity Rem2/Cavbeta4 interaction and show definitively that the interaction is required for Cav2.1

280 However, proving definitively that the model supports superconductivity i

281 lity mechanically cleaved HOPG, demonstrates definitively that the pristine basal surface supports fa

282 lmost exclusively at CpG islands and support definitively that these tumors were appropriately named.

283 basidiomycete fungi growing in agar, showing definitively that these widespread heterotrophic fungi c

284 Our results show definitively that Type I X-linked miRNA genes are subjec

285 Identifying definitively the controls over the rivermouth effect on

286 tures and activation of pathways to localize definitively the essential memory trace.

287 are an alternative source, but to ascertain definitively the identity and fidelity of cell types gen

288 Although too early to tell definitively, the observed die-out of OPV2-related virus

289 though fiber supplements have not been shown definitively to benefit patients with IBD, soluble fiber

290 n its early stages, and its development will definitively transform the fundamental understanding of

291 The patients definitively treated with in vitro active cefepime (case

292 At pH <7.4, the spectra are definitively type I, whereas at pH >/=7.4 the spectra ha

293 ers of age-matched individuals are needed to definitively understand the impact of BMI on epigenetic

294 ll genomic approaches are uniquely placed to definitively unravel complex clonal structures and tissu

295 To address these issues definitively, we developed RgIA4, a peptide that exhibit

296 nts underlying IAI have yet to be identified definitively; we argue that these molecules are surface-

297 ion of clinical trials designed to determine definitively whether screening for and treatment of M. g

298 intervention on neural activity to determine definitively whether specific neural activity features a

299 l cancer who were tested for MSI and treated definitively with chemoradiation followed by surgery.

300 ed 195 patients with stage III NSCLC treated definitively with radiation therapy between January 2008