ライフサイエンスコーパス: dehydrogenase

1 protein), and Hadh (encodes hydroxyacyl-CoA dehydrogenase).

2 ESCO) to guide the engineering of an alcohol dehydrogenase.

3 orylation Complex I, sirtuin 3 and succinate dehydrogenase.

4 functions as a long-chain aliphatic aldehyde dehydrogenase.

5 as observed, catalyzed by the enzyme lactate dehydrogenase.

6 ants in genes encoding subunits of succinate dehydrogenase.

7 loser to the FMN than they are in other NADH dehydrogenases.

8 flipping upon NAD(+) binding in proper NADH dehydrogenases.

9 s belonging to a novel family of short-chain dehydrogenases.

10 everal tissues express 11beta-hydroxysteroid dehydrogenase 1 (11beta-HSD1), including the skin.

11 s an oral inhibitor of the mutant isocitrate dehydrogenase 1 (IDH1) enzyme, approved for treatment of

12 as are driven by mutations in the isocitrate dehydrogenase 1 (IDH1) gene and are less aggressive than

13 Mutations in the isocitrate dehydrogenase 1 (IDH1) gene occur in most LGGs (> 70%).

14 Isocitrate dehydrogenase 1 (IDH1) mutations occur in approximately

15 rate via inhibition of the mutant isocitrate dehydrogenase 1 (IDH1; mIDH1) enzyme.

16 vivo regulation of Inosine-5'-monophosphate dehydrogenase 1 (IMPDH1) in the retina.

17 the cytosolic flavoprotein, NAD(P)H quinone dehydrogenase 1 (Nqo1), is strongly overexpressed in mou

18 b and enasidenib to target mutant isocitrate dehydrogenase 1 and 2, respectively.

19 (DCLK1), CD44 molecule (CD44), and aldehyde dehydrogenase 1 family member A1 (ALDH1A1).

20 xpression of the quiescent markers: Aldehyde Dehydrogenase 1 Family Member L1 (ALDH1L1) and Glutamate

21 f NRF2 and its targets NQO1 (NAD(P)H quinone dehydrogenase 1) and SLC7A11 (solute carrier family 7 me

22 d after EGFR activation in a GDH1 (glutamate dehydrogenase 1)-dependent manner.

23 yglutarate imaging is possible in isocitrate dehydrogenase 1-mutated human glioma by using a super-re

24 Mutations in the isocitrate dehydrogenase 1/2 (IDH1/2) enzymes occur in up to 65% of

25 dehydrogenase, [(13)C]bicarbonate), lactate dehydrogenase ([1-(13)C]lactate), and alanine transamina

26 HSD3B1 encodes for 3beta-hydroxysteroid dehydrogenase-1 (3beta-HSD1), which catalyzes peripheral

27 owing to somatic mutations in the isocitrate dehydrogenase-1 or -2 (IDH1 or IDH2) genes, or germline

28 nd inhibiting the expression of the sorbitol dehydrogenase-1 SODH-1, a crucial sugar metabolism enzym

29 tly, rs72613567:TA in hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13) was shown to be associated w

30 [TM6SF2] p.E167K; and hydroxysteroid 17-beta dehydrogenase 13 [HSD17B13] rs72613567) were combined in

31 kinase regulator, and hydroxysteroid 17-beta dehydrogenase 13) to NAFLD and expand the associated und

32 olism of [1-(13)C]pyruvate via PDH (pyruvate dehydrogenase, [(13)C]bicarbonate), lactate dehydrogenas

33 GE2-degrading enzyme 15-hydroxyprostaglandin dehydrogenase (15-PGDH) and increases PGE2 levels.

34 15-Prostaglandin dehydrogenase (15-PGDH) is the key enzyme in PGE(2) meta

35 increased amounts of 15-hydroxyprostaglandin dehydrogenase (15-PGDH), the prostaglandin E(2) (PGE(2))

36 rolled by the activity of the hydroxysteroid-dehydrogenase-17-beta-3 (HSD17B3).

37 As the cytosolic enzyme aldehyde dehydrogenase 1A3 turns out to be overexpressed in these

38 Alcohol dehydrogenase 1B (ADH1B) is involved in alcohol metaboli

39 in coded by CUX2), Glu504Lys of acetaldehyde dehydrogenase 2 (a protein encoded by ALDH2) and Glu4Gly

40 d leukemia (AML) treated with the isocitrate dehydrogenase 2 (IDH2) mutant-specific inhibitor enaside

41 ncluding the gene that encodes retinaldehyde dehydrogenase 2 (RALDH2), a rate-limiting enzyme in the

42 cavenger superoxide dismutase 1 and aldehyde dehydrogenase 2 was reduced, whereas the NOX2 (NADPH [ni

43 Mutations in isocitrate dehydrogenase-2 (IDH2) occur in around 5% of patients wi

44 eloid counterparts, depended on the aldehyde dehydrogenase 3a2 (Aldh3a2) enzyme that oxidizes long-ch

45 te dehydrogenase (G6PDH), 6-phosphogluconate dehydrogenase (6PGDH), and methylenetetrahydrofolate deh

46 ize chloroplast-localized 6-phosphogluconate dehydrogenase (6PGDH), PGD3, is critical for endosperm s

47 cassette subfamily A member 4 (-/-) /retinol dehydrogenase 8 (-/-) and wild-type BALB/c mice suscepti

48 mors to enhanced glycolytic flux and lactate dehydrogenase A (LDHA) activity (Warburg effect).

49 sphate synthetase (UMPS), as well as lactate dehydrogenase A (LDHA), establishing a mechanism by whic

50 Expression of lactate dehydrogenase A (LDHA), which catalyzes (13)C label exch

51 ll metabolism towards glycolysis and lactate dehydrogenase A (LDHA).

52 es, two alcohol dehydrogenases, two aldehyde dehydrogenases, a fatty-acid-CoA ligase, a fatty acid de

53 hydroxyacyl-coA dehydrogenase and succinate dehydrogenase activities, decreased lactate dehydrogenas

54 uxes evaluated, including substrate-specific dehydrogenase activities, respiratory responses, redox c

55 PDK-mediated decreases in pyruvate dehydrogenase activity and oxygen consumption rate were

56 trast to pO(2) and (18)F-FDG uptake, lactate dehydrogenase activity was distributed relatively evenly

57 ouble mutant showed the highest dye-mediated dehydrogenase activity with negligible oxidase activity,

58 LDH1A1 and stem-related genes, high aldehyde dehydrogenase activity, and CD133 positivity.

59 th protein folding, cell-cell adhesion, NADH dehydrogenase activity, ATP-binding, proteasome complex,

60 rioides) incidence, without inducing alcohol dehydrogenase activity, which suggests that coated fruit

61 nal antibody against the C. albicans alcohol dehydrogenase (Adh) 1.

62 icity in a classic functional trait, alcohol dehydrogenase (ADH) activity in D. melanogaster, across

63 ssociated with the activation of the alcohol dehydrogenase (ADH) and greater anaerobic metabolism in

64 tuning of alcohol oxidase (AOx) and alcohol dehydrogenase (ADH) biocatalysis towards butanol-1 oxida

65 robe gas-phase structural changes of alcohol dehydrogenase (ADH, 4mer) under varying degrees of in-so

66 associated with four genes encoding Alcohol Dehydrogenase - ADH1A, ADH1B, ADH1C and ADH4.

67 Acetaldehyde-alcohol dehydrogenase (AdhE) enzymes are a key metabolic enzyme

68 l beta-hydroxy nitriles catalyzed by alcohol dehydrogenase (AdhS) and halohydrin dehalogenase (HHDH)

69 ion of retinol into retinaldehyde by alcohol dehydrogenases (ADHs) or retinol dehydrogenases (RDHs);

70 -derived flavin adenine dinucleotide glucose dehydrogenase (AfGDH) and an electron transfer domain of

71 G is first oxidized by a NAD(P)(+)-dependent dehydrogenase (AHGD), which is a key step of this pathwa

72 SigG1 regulates the expression of alanine dehydrogenase, ald and the WhiB-like regulator, wblC req

73 n and fulvestrant increased MFE and aldehyde dehydrogenase (ALDH) activity of patient-derived xenogra

74 of NSCLC cells and increases their aldehyde dehydrogenase (ALDH) activity, which was identified to b

75 ples were segregated based on their aldehyde dehydrogenase (ALDH) activity.

76 GD and its homologs represent a new aldehyde dehydrogenase (ALDH) family with different substrate pre

77 p53 and aldehyde dehydrogenase (ALDH) have been implicated in key tumorig

78 ria Ca(2+) transfer promoted optimal alphaKG dehydrogenase (alphaKGDH) activity.

79 Hydroxyprostaglandin dehydrogenase, an enzyme required for 15-Oxo-ETE synthes

80 FdsABG is a soluble NAD(+)-dependent formate dehydrogenase and a member of the NADH dehydrogenase sup

81 among Black women and genes coding for NADH dehydrogenase and cytochrome c oxidase subunits.

82 esis pathways-inosine-5'-monophosphate (IMP) dehydrogenase and cytosine triphosphate (CTP) synthase.

83 atic mitochondrial activity through pyruvate dehydrogenase and elevating enterohepatic bile acid reci

84 sensing electrode composed of wired glucose dehydrogenase and enzymatic reference electrode composed

85 NMP with URC, including mitochondrial malate dehydrogenase and glutamic-oxaloacetic transaminase, pre

86 a result, HAX-1 ablation activates pyruvate dehydrogenase and increases mitochondria utilization of

87 tude taxa included increased hydroxyacyl-coA dehydrogenase and succinate dehydrogenase activities, de

88 ction of O(2) to H(2)O(2) is downstream from dehydrogenases and ubiquinone at the level of cytochrome

89 four (4%) of 100 had elevated serum lactate dehydrogenase, and 17 (17%) had two or more features.

90 identified markers of inflammation, lactate dehydrogenase, and creatinine as the variables most pred

91 ase (AST), alanine aminotransferase, lactate dehydrogenase, and creatinine correlated to fatality (od

92 lectrodes with b2LOxS and a DET-type glucose dehydrogenase, and evaluated their performance in the ar

93 hese advances, alkaline phosphatase, glucose dehydrogenase, and laccase were screened for immobilizat

94 abolic enzymes citrate synthase (CS), malate dehydrogenase, and strombine dehydrogenase remained cons

95 Aldehyde dehydrogenases are versatile enzymes that serve a range

96 s involved in lipid oxidation (e.g., alcohol dehydrogenase) are considerably higher in PE-fed larvae,

97 es, such as lymphopenia and elevated lactate dehydrogenase, are common, but nonspecific.

98 se A and pyruvate kinase, as well as lactate dehydrogenase, are enriched at the C. trachomatis inclus

99 Finally, using glutamate dehydrogenase as a case study, we observe increased in v

100 ter, we confirmed glyceraldehyde-3-phosphate dehydrogenase as a key target of IAA, specifically attac

101 CAM cycle involving mitochondrial isocitrate dehydrogenase as a potential contributor to initial carb

102 The results of a lactate dehydrogenase assay indicated that exposure to these cyc

103 compelling evidence that formylmethanofuran dehydrogenase B subunits, which catalyze the reduction o

104 ransfers one electron further to butyryl-CoA dehydrogenase (Bcd); two such transfers enable Bcd to re

105 ree rounds of directed evolution of an amine dehydrogenase biocatalyst via ultrahigh throughput dropl

106 Notably, inhibition of xanthine dehydrogenase by addition of allopurinol led to similar

107 es that adaptive activation of mitochondrial dehydrogenases by intramitochondrial Ca(2+) cannot be th

108 lsolin, tubulins, glyceraldehyde-3-phosphate dehydrogenase, calmodulin, ATP synthase, sperm equatoria

109 ving effect of carbon fixation by isocitrate dehydrogenase can reach 11% total water saving for the c

110 ydrogenase, fumarate hydratase or isocitrate dehydrogenase, can dysregulate specific 2OGDDs.

111 high glycolytic rates depends on the lactate dehydrogenase-catalyzed regeneration of NAD(+) from GAPD

112 genase (DH) domains of the enzyme cellobiose dehydrogenase (CDH) isolated from the fungi Neurospora c

113 Mo/Cu active site of aerobic carbon monoxide dehydrogenase (CODH) has been a long-standing synthetic

114 ction being catalyzed by the NADPH-dependent dehydrogenase CofA.

115 ependent enzyme and part of the 2-oxoadipate dehydrogenase complex (OADHc) in l-lysine catabolism.

116 levels by impairing lipoylation of the 2-OG dehydrogenase complex (OGDHc)-the rate limiting step for

117 bolic consequence of activating the pyruvate dehydrogenase complex (PDH) to increase pyruvate oxidati

118 in mouse metastasis models, drives pyruvate dehydrogenase complex (PDHc) activation to maintain TCA

119 via glucose oxidation by depressing pyruvate dehydrogenase complex activity.

120 The classical 2-oxoglutaric dehydrogenase complex can exist as a previously undiscov

121 inate accumulation despite reduced succinate dehydrogenase complex iron-sulfur subunit b (SDHB) expre

122 e interactions between CfrA and the pyruvate dehydrogenase complex or PII protein have been revealed.

123 a hybrid 2-oxoglutaric and 2-oxoadipic acid dehydrogenase complex.

124 Randomisation was stratified by lactate dehydrogenase concentration and geographical region.

125 In contrast, the inosine monophasphate dehydrogenase dedicated to guanosine synthesis, GuaB2, d

126 we show that loss of DHTKD1 in glutaryl-CoA dehydrogenase-deficient HEK-293 cells leads to a 2-fold

127 yrimidine biosynthetic enzyme dihydroorotate dehydrogenase (DHODH) is a validated target for malaria

128 The inhibition of dihydroorotate dehydrogenase (DHODH) with leflunomide impacts nucleotid

129 Human dihydroorotate dehydrogenase (DHODH), an enzyme in the de novo pyrimidi

130 pyrimidine synthesis pathway, dihydroorotate dehydrogenase (DHODH), and the blockage of uridine trans

131 s as an electron acceptor for dihydroorotate dehydrogenase (DHODH)-an enzyme necessary for de novo py

132 structures of the separate transmembrane and dehydrogenase domains, consistent with a flexible linker

133 te dehydrogenase (E1a, also known as DHTKD1, dehydrogenase E1, and transketolase domain-containing pr

134 2-Oxoadipate dehydrogenase (E1a, also known as DHTKD1, dehydrogenase

135 hanol dehydrogenases (MDHs) and ExaF ethanol dehydrogenases (EDHs), expanding the range of biological

136 renal activity and reduced hepatic glutamate dehydrogenase enzymatic activity.

137 For instance, mitochondrial succinate dehydrogenase enzyme levels as well as carbonic anhydras

138 By comparison, the formate dehydrogenase enzymes operate at relatively mild potenti

139 c levels in the RV, reduced phospho-pyruvate dehydrogenase expression, RV fibrosis, and hypertrophy a

140 idation of retinaldehyde into RA by aldehyde dehydrogenases family 1, subfamily A (ALDH1as), such as

141 ion library revealed that mutants in formate dehydrogenase (FDH) genes had the highest survival follo

142 The molybdenum-containing dehydrogenase FdsABG is a soluble NAD(+)-dependent forma

143 amine oxidase TynA and the aromatic aldehyde dehydrogenase FeaB.

144 In fed rats, Acipimox decreased pyruvate dehydrogenase flux (to 0.512 +/- 0.13, P = .04).

145 caused heart failure with decreased pyruvate dehydrogenase flux and poor ejection fraction reserve.

146 02), though this rise did not match pyruvate dehydrogenase flux observed in rats fed carbohydrate ric

147 catalytic activity similar to enzyme alcohol dehydrogenase for ETB.

148 e of IL-1beta, IL-18, caspase-1, and lactate dehydrogenase from the cell; and real-time analysis of c

149 G subcomplex of the cytosolic FdsABG formate dehydrogenase from the hydrogen-oxidizing bacterium Cupr

150 to mutations in the genes encoding succinate dehydrogenase, fumarate hydratase or isocitrate dehydrog

151 BACKGROUNDGlucose-6-phosphate dehydrogenase (G6PD) deficiency decreases the ability of

152 Glucose 6-phosphate dehydrogenase (G6PD) deficiency is 1 of the commonest hu

153 ysis in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency, necessitating screening

154 y occur in children with glucose-6-phopshate dehydrogenase (G6PD) deficiency.

155 The enzyme glucose-6-phosphate dehydrogenase (G6PD) is a major contributor to NADPH pro

156 from oxidative stress by glucose-6-phosphate dehydrogenase (G6PD).

157 er, higher activities of glucose 6-phosphate dehydrogenase (G6PDH), 6-phosphogluconate dehydrogenase

158 UVC activated the L-galactono-1,4-lactone dehydrogenase (GalDH), a key enzyme for vitamin C biosyn

159 tion of cytosolic glyceraldehyde-3-phosphate dehydrogenase (GAPC), but its nuclear function in plant

160 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a key enzyme involved in energy

161 channeling from D-glyceraldehyde-3-phosphate dehydrogenase (GAPDH) to L-lactate Dehydrogenase (LDH) u

162 lent inhibitor of glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a critical node in the glycolysis

163 Glutamate dehydrogenase (GDH) is a key enzyme interlinking carbon

164 e report biallelic mutations in the sorbitol dehydrogenase gene (SORD) as the most frequent recessive

165 in the fumarate hydratase (FH) and succinate dehydrogenase genes (SDHA, SDHB, SDHC and SDHD), respect

166 ansferase, alanine aminotransferase, lactate dehydrogenase, glucose, lactate, and pH) with graft feat

167 Catfish L-lactate dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase,

168 beta-2 microglobulin >= 5 mg/L, and lactate dehydrogenase > 250 U/L.

169 Ninety minutes lactate dehydrogenase had the strongest correlation with L-GrAFT

170 he mitochondrial enzyme beta-hydroxyacyl-CoA-dehydrogenase (HADH) can indicate previous freezing.

171 nzyme upstream of the defective glutaryl-CoA dehydrogenase, has been investigated as a potential ther

172 been realized using the beta-hydroxybutyrate dehydrogenase (HBD) enzymatic reaction and by addressing

173 e stable immobilisation of an NADH-dependent dehydrogenase (i.e. lactate dehydrogenase), via EDC/S-NH

174 y was poorer when tumors harbored isocitrate dehydrogenase (IDH) mutations (91% in IDH-wild-type tumo

175 Background Isocitrate dehydrogenase (IDH) mutations are highly frequent in gli

176 ble MRI parameters for predicting isocitrate dehydrogenase (IDH) status in patients with glioma.

177 hether MRI/CT analysis identifies isocitrate dehydrogenase (IDH)-mutant gliomas misassigned to 1p/19q

178 CMA degrades isocitrate dehydrogenases IDH1 and IDH2 and reduces levels of intra

179 gies and single-gene mutations in isocitrate dehydrogenases (IDH1/2).

180 Inosine-5'-monophosphate dehydrogenase (IMPDH) has been proposed as a potential d

181 Inosine monophosphate dehydrogenase (IMPDH) mediates the first committed step

182 s and stimulated gene expression of acyl-CoA dehydrogenases in the liver.

183 l fluid biomarkers (pH, glucose, and lactate dehydrogenase) in parapneumonic effusions.Methods: Patie

184 (2) stabilization by 15-hydroxyprostaglandin dehydrogenase inhibitor or EP2 or EP4 receptor agonists

185 n of PGE(2) level by 15-hydroxyprostaglandin dehydrogenase inhibitor protected mice against anaphylax

186 isease, >1 extranodal site, elevated lactate dehydrogenase, International Prognostic Index (IPI) 3-5,

187 nthesis, but that assembly of RCI (i.e. NADH dehydrogenase) is far less efficient, with dramatic over

188 Here, we show that pyruvate dehydrogenase kinase (PDK)-2 plays a role in hypothalami

189 nd dephosphorylates and inactivates pyruvate dehydrogenase kinase 1, Akt, Raf, mitogen-activated prot

190 splice site mutation in the canine pyruvate dehydrogenase kinase 4 (PDK4) gene has been shown to be

191 Knockdown of pyruvate dehydrogenase kinase 4 (PDK4) or inhibition with dichlor

192 Our results show that pyruvate dehydrogenase kinase inhibition improves the contractile

193 ontaining no supplement or the PDK (pyruvate dehydrogenase kinase) inhibitor dichloroacetate was star

194 ne deacetylase, cyclooxygenase, and pyruvate dehydrogenase kinase.

195 e transaminase (P = .0040); elevated lactate dehydrogenase (LDH) (P < .0001); and increased procalcit

196 Lactate dehydrogenase (LDH) accounts for the fermentative compon

197 Cell viability, cell number, lactate dehydrogenase (LDH) activity, cell necrosis, transepithe

198 Increased levels of lactate dehydrogenase (LDH) and decreased levels of succinate de

199 erobic glycolysis, robustly inducing lactate dehydrogenase (LDH) and lactate production, whereas IL-2

200 fficient magnitude to increase serum lactate dehydrogenase (LDH) and was oxidative in nature as shown

201 ts using fluorescence microscopy and Lactate dehydrogenase (LDH) assay on the supernatant.

202 Lactate dehydrogenase (LDH) catalyzes the conversion of pyruvate

203 L-6 level, C-reactive protein level, lactate dehydrogenase (LDH) level, ferritin level, d-dimer level

204 phosphate dehydrogenase (GAPDH) to L-lactate Dehydrogenase (LDH) using enzymes from different cells.

205 te TMAO to protect proteins, such as lactate dehydrogenase (LDH), against hydrostatic pressure stress

206 for prostate-specific antigen (PSA), lactate dehydrogenase (LDH), and CgA at baseline and in follow-u

207 Lactate dehydrogenases (LDHs) are tetrameric enzymes of major si

208 ) and NADH were reacted in situ with leucine dehydrogenase (LeuDH) to generate l-norleucine with 2-ke

209 P = .035), d-dimer level (P < .001), lactate dehydrogenase level (P < .001), and C-reactive protein l

210 lymphoma (stage III with an elevated lactate dehydrogenase level or stage IV) or acute leukemia to co

211 observed in 139 (88%), and elevated lactate dehydrogenase level was observed in 128 (81%).

212 hil count, C-reactive protein level, lactate dehydrogenase level, distribution of lung disease, and c

213 nt, neutrophil/lymphocyte ratio, and lactate dehydrogenase level.

214 -specific first mammalian NDE (external NADH dehydrogenase)-like enzyme, Aifm2 oxidizes NADH to maint

215 is distinct from the flavoprotein L-lactate dehydrogenase (LldD).

216 ve, iron-sulfur cluster-containing L-lactate dehydrogenase (LutACB), that is distinct from the flavop

217 regation of model substrates, such as malate dehydrogenase (MDH), and inhibits disaggregation of luci

218 ine quinone (PQQ) in bacterial XoxF methanol dehydrogenases (MDHs) and ExaF ethanol dehydrogenases (E

219 us studies have shown that mutant isocitrate-dehydrogenase (mIDH)1/2 glioma cells convert alpha-KG to

220 proving the concept that targeting aldehyde dehydrogenase might represent a novel and promising way

221 enase (6PGDH), and methylenetetrahydrofolate dehydrogenase (MTHFD) may be the reason for the sufficie

222 nificantly decreased 15-hydroxyprostaglandin dehydrogenase [NAD((+))], which degrades eicosanoids, wa

223 ing simple clinical parameters (age, lactate dehydrogenase, number/sites of involvement, stage, perfo

224 nificance of the DHTKD1-encoded 2-oxoadipate dehydrogenase (OADH) remains obscure due to its catalyti

225 lcarnitine and demonstrate that oxoglutarate dehydrogenase (OGDH) is responsible for this remaining g

226 h the ubiquitous OGDH-encoded 2-oxoglutarate dehydrogenase (OGDH).

227 ng NADH and the enzyme 3alpha-hydroxysteroid dehydrogenase onto the MB-SPCE surface; samples of adipo

228 crystallin or alphaB-crystallin with alcohol dehydrogenase or citrate synthase by applying thermal st

229 , including survival in the elevated lactate dehydrogenase or EGFR and ALK wild-type populations.

230 ss2242 gene, encoding a putative short-chain dehydrogenase/oxidoreductase (SDR) in Burkholderia pseud

231 d abundance of the gene encoding butyryl-coA dehydrogenase (P=0.02).

232 e pentose phosphate and glycerol-3-phosphate dehydrogenase pathways.

233 anerochaete chrysosporium-derived cellobiose dehydrogenase (Pcyb) was previously reported to show the

234 ate synthetase (P5CS) and decreasing proline dehydrogenase (PDH) activity, while Si reversed these ef

235 We define a pyruvate dehydrogenase (PDH) dependency in leader cells that can

236 roups of eight Wistar rats, we used pyruvate dehydrogenase (PDH) flux studies to demonstrate changes

237 rophages reroute pyruvate away from pyruvate dehydrogenase (PDH) in an NO-dependent and hypoxia-induc

238 rrier protein (AAC) 1 and AAC2, and pyruvate dehydrogenase (PDH) were assessed by respirometry and We

239 dehydrogenase phosphatase (PDP) and pyruvate dehydrogenase (PDH), dramatically increased PDH activity

240 ells increased nuclear pyruvate and pyruvate dehydrogenase (PDH), which induced histone acetylation a

241 ve detection of Plasmodiumfalciparum lactate dehydrogenase (PfLDH) in whole blood samples.

242 glucose-metabolizing enzyme phosphogluconate dehydrogenase (PGD).

243 ing serine by inhibition of phosphoglycerate dehydrogenase (PHGDH) leads to the accumulation of deoxy

244 ltiple testing adjustments, phosphoglycerate dehydrogenase (PHGDH) was the only gene that exhibited c

245 Phosphoglycerate dehydrogenase (PHGDH), the first rate-limiting enzyme of

246 d with serine biosynthesis (Phosphoglycerate dehydrogenase, Phgdh; phosphoserine aminotransferase-1,

247 ation, altered expression levels of pyruvate dehydrogenase phosphatase (PDP) and pyruvate dehydrogena

248 udes glycolytic enzymes (glucose-6-phosphate dehydrogenase, phosphofructokinase), DNA repair molecule

249 noacid catabolizing enzymes, notably proline dehydrogenase (POX), and adipose triglyceride lipase (AT

250 on rate levels, and had higher serum lactate dehydrogenase, procalcitonin, and interleukin-6 levels.

251 ic proposals for hydride transfer in formate dehydrogenase proceed through a classic metal hydride.

252 Proline dehydrogenase (PRODH) is activated to reduce proline lev

253 ptosis or stimulated nitric oxide or lactose dehydrogenase production in mature osteoclasts.

254 tochondria-targeted, bacterial-type acyl-CoA dehydrogenase (PtMACAD1) that is present in Stramenopile

255 te dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, pyruvate kinase, and glucose-6-phosphate

256 dehydrogenase activities, decreased lactate dehydrogenase, pyruvate kinase, creatine kinase, and cyt

257 of the UMP-generating enzymes dihydroorotate dehydrogenase (quinone) (DHODH) and uridine monophosphat

258 by alcohol dehydrogenases (ADHs) or retinol dehydrogenases (RDHs); and oxidation of retinaldehyde in

259 Rv2509 belongs to the short-chain fatty acid dehydrogenase/reductase (SDR) family, but with some dist

260 dicted to encode a member of the short-chain dehydrogenase/reductase (SDR) superfamily, but its poten

261 ndent epimerase belonging to the short-chain dehydrogenase/reductase family.

262 ells, pH, D/L-lactate production and lactate dehydrogenase relative abundance were assessed.

263 i adhesion to epithelial cells and D-lactate dehydrogenase relative abundance.

264 se (CS), malate dehydrogenase, and strombine dehydrogenase remained constant throughout the day/night

265 resulted from higher activities of succinate dehydrogenase (SDH) and cytochrome c oxidase (CCO).

266 eased that of the metabolic enzyme succinate dehydrogenase (SDH) in the tumor cells.

267 Mutations in succinate dehydrogenase (SDH) lead to the development of tumors in

268 nase (LDH) and decreased levels of succinate dehydrogenase (SDH) were also detected.

269 enes encoding the four subunits of succinate dehydrogenase (SDH), a mitochondrial membrane-bound enzy

270 hologic characteristics predicted isocitrate dehydrogenase status in World Health Organization grade

271 electrons in the respiratory chain flow from dehydrogenases' substrates through quinones and then cyt

272 tated 28 C-terminal residues within the NADH dehydrogenase subunit 4.

273 n S12 (RPS12), the 5' editing domain of NADH dehydrogenase subunit 7 (ND7 5'), and C-rich region 3 (C

274 l DNA (mtDNA) mutations associated with NADH dehydrogenase subunits and nuclear gene mutations that a

275 ding those for ATP6, ATP8 synthase, and NADH dehydrogenase subunits, supporting electron microscopy (

276 especially for ATP6, ATP8 synthase, and NADH dehydrogenase subunits.

277 te of a copper-containing enzyme thiocyanate dehydrogenase (suggested EC 1.8.2.7) that was purified f

278 ng the evolution of the prokaryotic aldehyde dehydrogenase superfamily and their diversity of functio

279 rmate dehydrogenase and a member of the NADH dehydrogenase superfamily.

280 e report CIU-ECD experiments for the alcohol dehydrogenase tetramer, demonstrating improved sequence

281 ubunit of the branched chain alpha-keto acid dehydrogenase that is required for the second and rate-l

282 nd validate a group of microbial cholesterol dehydrogenases that contribute to coprostanol formation.

283 Ca(2+) uptake precedes activation of matrix dehydrogenases, thereby matching OXPHOS substrate supply

284 oyl succinyltransferase and dihydrolipoamide dehydrogenase to form a hybrid 2-oxoglutaric and 2-oxoad

285 rain PtoDC3000 uses an indole-3-acetaldehyde dehydrogenase to synthesize the phytohormone indole-3-ac

286 ma cell leukaemia and elevated serum lactate dehydrogenase (two times the upper limit of normal or mo

287 uding two alkane monooxygenases, two alcohol dehydrogenases, two aldehyde dehydrogenases, a fatty-aci

288 KO fetal lungs encodes 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1), which catalyzes conv

289 me, we identified the 17-beta-hydroxysteroid dehydrogenase type 12 (HSD17B12) as a human hub of the v

290 rom pyruvate to lactate catalyzed by lactate dehydrogenase using hyperpolarized (13)C magnetic resona

291 n NADH-dependent dehydrogenase (i.e. lactate dehydrogenase), via EDC/S-NHS chemistry, for the fabrica

292 By choosing a suitable sorbitol dehydrogenase, we designed yeast strains in which the so

293 ns lacking yggS and serA (3-phosphoglycerate dehydrogenase) were conditionally lethality in the M9-gl

294 pleural biomarkers (pH, glucose, and lactate dehydrogenase) when predicting the referral for intraple

295 Pharmacologic inhibitor of pyruvate dehydrogenase, which controls the transition from glycol

296 NAD(+)/NADH ratio via the enzyme UDP-glucose dehydrogenase, which oxidizes the alcohol group at C6 to

297 we show here, lanthanide-dependent methanol dehydrogenases, which are more prevalent in the environm

298 retrospectively selected (36 with isocitrate dehydrogenase wild-type [IDH(wt)], 16 with mutant 1p/19q

299 uccessfully prepared by constructing glucose dehydrogenase with two different catcher domains at the

300 he periplasmic lanthanide-dependent methanol dehydrogenase XoxF1 produces formaldehyde, which is leth