ライフサイエンスコーパス: delivery system

1 t (e.g., solid dispersions, lipid-based drug delivery systems).

2 mized trial in a large integrated healthcare delivery system.

3 ed via a custom-built MRI-compatible tastant-delivery system.

4 e - specifically a HPMA copolymer-based drug delivery system.

5 of its hospital-centric and treatment-based delivery system.

6 onal immiscible carrier solvent into the ink delivery system.

7 using a modified vibrating mesh aerosol drug delivery system.

8 ralized Modules for Membrane Antigens (GMMA) delivery system.

9 ted in 10 pigs using a dedicated transseptal delivery system.

10 cating their potential as an anticancer drug delivery system.

11 uaternary complex that functions as an siRNA delivery system.

12 nsive release behavior of the on-demand drug delivery system.

13 stem open up possibilities for an all-in-one delivery system.

14 lucan-chitin particles (GCPs) as an adjuvant-delivery system.

15 uss the recent discoveries on non-viral gene delivery systems.

16 advances for the development of ocular drug delivery systems.

17 inted drug products and nanofiber-based drug delivery systems.

18 sign safer and more efficient nanobased drug delivery systems.

19 o fabricate bespoke medical devices and drug delivery systems.

20 of classical dosage forms and advanced drug delivery systems.

21 teractions and the development of novel drug delivery systems.

22 tion with an ACB moiety are described as NTP delivery systems.

23 vel of complexity that will challenge health delivery systems.

24 drophobicity and thus loading in lipid-based delivery systems.

25 an adapt to working in different health-care delivery systems.

26 conducive for use in the preparation of drug delivery systems.

27 gle dose in order to design improved vaccine delivery systems.

28 acy and safety of current therapies and drug delivery systems.

29 ffers a route to novel anticancer agents and delivery systems.

30 and perspectives to achieve efficient drugs delivery systems.

31 limited in scope in regard to polymeric drug delivery systems.

32 y in free form and using nanoparticles-based delivery systems.

33 mitations in the context of anti-cancer drug delivery systems.

34 n and peptide stability within polymer-based delivery systems.

35 otein/peptide stability within polymer-based delivery systems.

36 eveloped as the next generation of pesticide delivery systems.

37 uous glucose monitors, and automated insulin delivery systems.

38 s engineering of more robust immune adjuvant delivery systems.

39 es are then superassembled to form multidrug delivery systems.

40 c combinations or chemotherapeutics in novel delivery systems.

41 additional applications of antibody-mediated delivery systems.

42 s a guiding reference to formulate sustained delivery systems.

43 ering to high-performance filtering and drug delivery systems.

44 o drug release kinetics of nanoparticle drug delivery systems.

45 ne the effectiveness of novel non-viral gene delivery systems.

46 ibility, cost, efficacy, and tolerability of delivery systems.

47 l approach for targeted supersaturating drug delivery systems.

48 tate transcutaneous delivery of nanoparticle delivery systems.

49 icinoids including prodrugs, conjugates, and delivery systems.

50 ntionally the target of erythrocyte-mediated delivery systems.

51 ) for the development of peptide and protein delivery systems.

52 rove the poor clinical success of local drug delivery systems.

53 ble strategy for the development of new drug delivery systems.

54 eering, development of microarrays, and drug delivery systems.

55 he recent development on the pulmonary siRNA delivery systems.

56 ar approaches for glucose-responsive insulin delivery systems, a rapidly growing subfield of precisio

57 Here, a neutrophil-mediated delivery system able to transport drug-loaded nanocarrie

58 Among viral delivery systems, adeno-associated viruses (AAVs) are re

59 Functionalized drug delivery systems against malignant lung metastasis of br

60 using a piezoelectric pressure-driven fluid delivery system and a squaraine rotaxane fluorophore, Se

61 been integrated on a DMF platform: a reagent delivery system and a thermal control apparatus.

62 te delivery systems induced a depot (of both delivery system and antigen) at the injection site, the

63 o the targeted subretinal site using a novel delivery system and suprachoroidal approach for most par

64 ) cells in 50 mul, using the custom-designed delivery system and surgical procedure.

65 Nano-fabricated smart drug delivery systems and implantable drug loaded biomaterial

66 . biosensors, microfluidic bioreactors, drug delivery systems and Lab-On-Chip).

67 ch as new symptomatic drugs, innovative drug delivery systems and novel surgical interventions give h

68 effects of stage at diagnosis, radiotherapy delivery system, and simultaneous HPV vaccination (75% c

69 large, multi-hospital, integrated healthcare delivery system, and to subsequently demonstrate its uti

70 tem goes beyond ensuring coverage, efficient delivery systems, and affordability.

71 mized clinical trials embedded in healthcare delivery systems, and facilitating effective collection

72 plicing system is adaptable to multiple gene delivery systems, and it presents new opportunities for

73 the rapidly changing landscape of healthcare delivery systems, and our evolving recognition that effo

74 towards the generation of glucose-responsive delivery systems, and provides commentary on the opportu

75 bling tissue models, engineering therapeutic delivery systems, and screening drugs.

76 These delivery systems are based on in situ forming gels, nano

77 on of electrospun and electrosprayed protein delivery systems are discussed.

78 As the physicochemical properties of drug delivery systems are governed not only by the material p

79 However, effective miRNA-delivery systems are needed for such approaches to be su

80 clusive research in psychology suggests that delivery systems are one primary determinant of costs an

81 Micelles, as a class of drug delivery systems, are underrepresented among United Stat

82 loyed various free radical-incorporated drug delivery systems as an approach to target biofilm format

83 Transdermal drug delivery systems as films not only avoids first-pass met

84 lar attention in the fabrication of advanced delivery systems as sophisticated carriers for therapeut

85 e cylindrical nano-vectors as cancer vaccine delivery systems as well as the obstacles their clinical

86 preclinical evidence for electronic nicotine delivery system-associated neurovascular impairment is p

87 Self-powered drug-delivery systems based on conductive polymers (CPs) that

88 Drug delivery systems based on electrospun fibers have been u

89 h the pandemic rapidly spreading, and health delivery systems being overwhelmed, it is imperative tha

90 tients enrolled in an integrated health care delivery system between 2005 and 2012 (with follow-up th

91 bioelectronics applications, including drug delivery systems, biosensing and electrical modulation o

92 a primary health-care (PHC)-based integrated delivery system by aligning the incentives and governanc

93 spun nanofibers based "fast dissolving" drug delivery systems by employing variety of polymers, drug

94 rovide proof of concept that this novel drug delivery system can precisely reverse the multidrug resi

95 The advanced drug delivery systems can improve the macrophage-based therap

96 d smart "all-in-one" nanoparticle-based drug delivery system capable of overcoming biological barrier

97 troduce a non-viral, ligand-mediated protein delivery system capable of selectively targeting primary

98 tic strategies, it is fundamental to develop delivery systems capable of preserving the biological ac

99 the public, patients, providers, healthcare delivery systems, communities, policy makers, and legisl

100 ophage (phage) have attractive advantages as delivery systems compared with mammalian viruses, but ha

101 inting, we have developed an intraoral light delivery system consisting of modular 3D printed light a

102 In this study, electrospun membrane drug delivery systems consisting of the antibiotic ciprofloxa

103 as a fast, safe, and user-friendly chemical delivery system containing all reagents (catalyst, ligan

104 commonly used therapy, introduce local drug delivery systems currently on the market or in the devel

105 Over the last several decades, numerous drug delivery systems (DDS) have been developed in order to i

106 learable gold nanoparticle (AuNP)-based drug delivery systems (DDSs) in the delivery of doxorubicin (

107 Spurred by newly developed drug delivery systems (DDSs), side effects of cancer chemothe

108 ers are one kind of these newly emerged drug delivery systems (DDSs), which enable drugs to rapidly p

109 However, currently available needle delivery systems deform and move soft tissue and organs,

110 The first-generation Portico valve and delivery system did not offer advantages over other comm

111 reatment, i.e., > 1 month) over conventional delivery systems (e.g., PEG-PLA micelles with no co-enca

112 EDS-FLU (93, 186, or 372 mug) or exhalation delivery system (EDS)-placebo for 24 weeks (16 double-bl

113 e overexpression of Btg2 using an adenoviral delivery system elevated FGF21 production by upregulatin

114 Electronic nicotine delivery systems (ENDS) are prefilled, battery-operated

115 Electronic nicotine delivery systems (ENDS) are rapidly increasing in popula

116 Electronic nicotine delivery systems (ENDS) or e-cigarettes have emerged as

117 The use of electronic nicotine delivery systems (ENDS), also known as e-cigarettes, wit

118 Here, recent advances in targeted exosomal delivery systems engineered by aptamer for future strate

119 An optical delivery system equipped with a nanomanipulator and a fi

120 s, social determinants of health, and health delivery system factors; and then proposes a set of solu

121 Drug delivery systems featuring first-order release kinetics

122 developed hydrogels from amnion tissue as a delivery system for ADSCs.

123 peptide-targeted EMs can be a promising drug delivery system for advanced PC.

124 Our aim was to develop a drug delivery system for angiotensin-(1-9).

125 demonstration of employing DNA transfer as a delivery system for antibodies that block transmission o

126 eatment of PCBs using an AC agglomerate as a delivery system for bioamendments is particularly well-s

127 d the uses of casein-based hydrogels as drug delivery system for both hydrophobic and hydrophilic mol

128 The application of nanocarriers as drug delivery system for chemotherapeutic drugs has become a

129 p soya lecithin and Tween 80 based vitamin D delivery system for food additives and nutraceutical com

130 udy can be utilized in devising an effective delivery system for Golden Rice(R) to the consumer.

131 (lipoMSN) is reported as an effective CRISPR delivery system for multiplex gene-editing in the liver.

132 nse provides an effective, mosquito-specific delivery system for potent insect-selective toxins.

133 ucleoside-based supramolecular gel as a drug delivery system for proteins with different properties a

134 and the utility of TNT-like protrusions as a delivery system for regenerative medicine.

135 Thus, they represent a potent drug delivery system for the application in a variety of trea

136 polymeric microspheres are suitable as drug delivery system for the sustained systemic delivery of t

137 d for developing a locally administered drug delivery system for treating DCIS, for which no primary

138 However, the lack of optimum delivery systems for ADSCs limits its use in the clinic.

139 est that niosomal vesicles might be suitable delivery systems for anthocyanins.

140 will enable discovery of more effective drug delivery systems for brain.

141 Various delivery systems for DSF and Cu were developed to enhanc

142 as bile and serum biomarkers and therapeutic delivery systems for iCCA will be described.

143 d by the lack of safe and effective nonviral delivery systems for in vivo therapeutic genome editing.

144 pplication of free radical-incorporated drug delivery systems for inhibiting biofilm formation and er

145 d particles are one of the most investigated delivery systems for mRNA formulations.

146 particles (LNPs) have potential as non-viral delivery systems for mRNA therapies.

147 Preparation of sophisticated delivery systems for nanomedicine applications generally

148 serve as anticaking agents, nano-additives, delivery systems for nutraceuticals, etc.

149 se-modifying drugs as well as potential drug delivery systems for OA and IVDD therapy.

150 rticle-, microparticle-, and nanofiber-based delivery systems for oral and oromucosal application.

151 Currently available drug delivery systems for oral diseases suffer from short ret

152 Automated insulin delivery systems for people with type 1 diabetes rely on

153 rs for use as effective supersaturating oral delivery systems for poorly water-soluble drugs.

154 Targeted exosomal delivery systems for precision nanomedicine attract wide

155 lesion location, there are no effective drug delivery systems for the therapy of TAD.

156 Developing safe and efficient delivery systems for therapeutic biomacromolecules is a

157 study investigated the impact of malting as delivery-system for endogenous enzymes.

158 es associated with protein/peptide polymeric delivery systems from an engineering approach oriented t

159 This delivery system further improves the nasal absorption as

160 Due to their cationic nature, all delivery systems gave high antigen loading (> 85%) with

161 An effective delivery system has been utilised to encapsulate the siF

162 A range of cationic delivery systems have been investigated as vaccine adjuv

163 e this barrier, nanoparticle (NP) based drug delivery systems have been reported.

164 Local drug delivery systems have been widely explored to reduce the

165 Cell-based drug delivery systems have generated an increasing interest i

166 low effectiveness associated with suboptimal delivery systems have impeded their use in translational

167 Oral drug delivery systems have multiple goals, assessing and enab

168 Nanoparticle-based delivery systems have shown highly significant potential

169 The electrospun nanofiber based drug delivery systems have shown tremendous advancements over

170 lized nature of these chronic diseases, drug delivery systems have the potential to enhance therapeut

171 Zero-order drug delivery systems have the potential to overcome the issu

172 Therapeutic delivery of drug and gene delivery systems have to traverse multiple biological ba

173 kers or regular users of electronic nicotine delivery systems (i.e., "e-cigarettes") likely undergo s

174 The nanoparticles (NPs)-mediated drug delivery systems improve drug solubility and bioavailabi

175 Using a novel biomaterial-based drug delivery system in the form of a hydrogel to achieve loc

176 omedical research, providers, and healthcare delivery systems in advancing the care of patients and t

177 This review showcases local drug delivery systems in different inflammatory diseases, inc

178 cotine, tobacco use, and electronic nicotine delivery systems in order to achieve ACP's vision for a

179 s of HPMC predetermine its use in oromucosal delivery systems including mucoadhesive tablets and film

180 Similarly, whilst the particulate delivery systems induced a depot (of both delivery syste

181 e a novel sustained-release intraocular drug delivery system (IODDS) for the treatment of glaucoma.

182 A closed-loop implantable drug delivery system is an ideal solution to minimize the res

183 The NP delivery system is composed of a polymeric NP which acts

184 wered on-skin iontophoretic transdermal drug-delivery system is developed as an on-skin chemical inte

185 nanoparticles' utility as a drug or genetic delivery system is of particular interest in transplanta

186 Herein, a nanocapsule-based delivery system is reported that enables intravenously i

187 Targeting drug delivery systems is crucial to reducing the side effects

188 A myriad of nano-scale therapeutic delivery systems is emerging as potential future medicin

189 amework of the state-of-the-art RBC-mediated delivery systems is explained in detail to inspire the d

190 ic efficacy of conventional transdermal drug delivery systems is often limited because the HS tissue

191 mental restructuring of payment policies and delivery systems is required to achieve a health care sy

192 ng and integration with biomaterials or drug delivery systems, is examined.

193 delivery of rapamycin via a biomimetic drug delivery system, it is possible to reduce vascular infla

194 is the lack of an efficient and safe in vivo delivery system, limiting most of the current gene thera

195 t of diabetes within two clinically-relevant delivery systems (liposomes and in human serum albumin [

196 ese results suggested that this coaxial drug-delivery system loaded with Ade provided a promising and

197 An oral biologic delivery system must aid in both localization and permea

198 In this regard, nanoscale drug delivery systems (Nano-DDS) have led to the expectation

199 xt generation of bacteriocin nano-sized drug delivery systems (Nano-DDS).

200 es for the application of nano targeted drug-delivery systems (Nano-TDDS) in cancer therapy.

201 entries as core components of nanoscale drug delivery systems (NDDSs) by making use of analytical ult

202 ucted a natural-lipid (NL) nanoparticle drug delivery system (NP-DDS) to encapsulate 6-shogaol and un

203 Here, we designed a novel delivery system of CpGODN based on its conjugation to se

204 hree naturally occurring allergens and novel delivery system of CSF1R inhibitor encapsulated nanoprob

205 ined with other lipids, can be a useful oral delivery system of molecules sensitive to digestive enzy

206 work provides valuable insight for designing delivery systems of bioactive compounds with optimal fun

207 Oil-in-water (O/W) emulsions are important delivery systems of omega-3 fatty acids (n-3 FA).

208 ations of retinoids, the development of drug delivery systems offers several advantages for clinical

209 Electronic nicotine delivery systems (often known as e-cigarettes) are a nov

210 n tobacco cigarettes and electronic nicotine delivery systems, on mouse alpha3beta4 nAChRs transientl

211 with the first generation Portico valve and delivery system or a commercially available valve (eithe

212 acco products (including electronic nicotine delivery systems or e-cigarettes) among children and ado

213 vestigating the intramucus transport of drug delivery systems or food nanoparticles.

214 embranes, the dynamics of vesicle-based drug delivery systems, or, more generally, the behaviour of p

215 g approach to develop novel imaging and drug delivery systems, owing to the ease with which these NPs

216 DFO administration using a transdermal drug delivery system prior to and immediately following irrad

217 In vitro evaluation showed that the delivery system prolonged the release kinetics while mai

218 Injectable, long-acting drug delivery systems provide effective drug concentrations i

219 This synergistic gene delivery system provides a viable method for highly effi

220 ly promising for further development, as the delivery system provides inherent antioxidant benefits t

221 ely affect neighbors, through explicit toxin delivery systems, provides them with an opportunity to m

222 requires both fast-acting neurotoxins and a delivery system quick enough to exceed the prey fish's r

223 We then optimized the RNA/delivery system ratio for in vivo delivery using saRNA c

224 g use of agarose-based biomaterials for drug delivery systems resulted in rapid growth in the number

225 reby contributing to the development of drug delivery systems satisfying clinical requirements.

226 rect administration procedure, suitable drug delivery system, selection of effective and safe dosage

227 ve of this study was to develop a novel drug delivery system, solid lipid nanoparticle (SLN), capable

228 cs, together with changes in the cancer care delivery system such as passage of the Affordable Care A

229 and oxidative stability of high-fat omega-3 delivery systems such as fish oil-in-water emulsions sta

230 heter delivery, and neuro-surgically applied delivery systems such as polymeric hydrogels and interst

231 Overall, implementation of local drug delivery systems such as this could reduce the need for

232 Several other modified delivery systems such as transdermal microneedle patches

233 In addition, new drug delivery systems, such as implants and transdermal devic

234 Local drug delivery systems, such as in situ forming implants (ISFI

235 Advanced biomaterials and drug delivery systems, such as nanoparticles and the use of T

236 we designed a dual functionalized liposomal delivery system, surface modified with transferrin (Tf)

237 s work was to develop an injectable hydrogel delivery system that can allow localized release of neur

238 application of a stable, multiplexed PB gRNA delivery system that can be widely exploited to further

239 The design of a non-viral gene delivery system that can release a functional nucleic ac

240 To generate an efficient exosomal delivery system that can target cardiomyocytes, we engin

241 ds within liposomes, a well-established drug delivery system that enables payload stability and enhan

242 stem to evaluate a target-specific pesticide delivery system that exploits the interconnected nature

243 tes (e-cigarettes) are an alternate nicotine delivery system that generate a condensation aerosol to

244 , biodegradable, and removable polymer-based delivery system that offers sustained drug delivery for

245 e neuronal stem cells requires an engineered delivery system that promotes integration of transplante

246 Here we report a delivery system that provides controlled release of insu

247 SLs) are a promising stimuli-responsive drug delivery system that rapidly releases DOX in response to

248 This study employs a drug delivery system that specifically delivers the PDE4 inhi

249 skin explants and, we explore a more modular delivery system that utilizes mRNA added to pre-formed n

250 to revolutionize medicine by designing drug delivery systems that are both efficacious and highly se

251 However, lack of suitable siRNA delivery systems that demonstrate excellent circulation

252 sorption of orally dosed compounds from drug delivery systems that generate supersaturation within th

253 Glucose-responsive insulin delivery systems that mimic pancreatic endocrine functio

254 Long-acting (LA) ARV formulations or delivery systems that reduce dosing frequency may increa

255 vitro tool for development and validation of delivery systems that transport drugs and therapeutic an

256 We developed a nucleoside triphosphate (NTP) delivery system (the TriPPPro approach), in which the ga

257 wards) prioritised reforming its health-care delivery system through: (1) systemic reform of public h

258 the capability for a self-adjuvanting cyclic delivery system to act as a vehicle for the delivery of

259 SHV LANA-targeted CRISPR-Cas9 and adenoviral delivery system to disrupt KSHV latency in infected epit

260 (MNs) have been proposed as a suitable drug delivery system to facilitate intradermal delivery of au

261 AE vectors may provide a clinically relevant delivery system to lung epithelium.

262 the significance of developing a smart nano-delivery system to optimize the delivery efficiency of a

263 Here, we describe a delivery system to overcome lymphatic and intra-lymph no

264 We expect this NP-mediated gene delivery system to provide safe and sustained release of

265 ic IMmune Editing, a CRISPR-Cas9 bone marrow delivery system to rapidly evaluate gene function in inn

266 s study aimed to fabricate an efficient drug-delivery system to reduce the undesirable side effects a

267 can have appreciable value in using the LPA delivery system to study pulmonary Q fever pathogenesis

268 velop, for the first time, an intradermal MN delivery system to target proinsulin, a large multi-epit

269 biodegradable nanoparticles (NPs) as a drug delivery system to the lesion site in rat and pig contus

270 is study, the feasibility of using nanoscale delivery systems to control release and prolong mammary

271 ity may afford opportunities to develop drug delivery systems to improve efficacy and reduce toxicity

272 ent of therapeutic agents and more effective delivery systems to promote cartilage repair.

273 n the engineering of bacteria as therapeutic delivery systems to selectively release therapeutic payl

274 ties to use site-directed, programmable drug delivery systems to treat auditory and vestibular disord

275 neficial in developing precise contraceptive delivery system, to enhance the quality of life for wome

276 l to provide a new level of control for drug delivery systems, tumor detection markers, biosensors, a

277 We have designed a lipopeptide oral delivery system using a B-cell epitope derived from the

278 , we outline the development of a cell-based delivery system using macrophages as a delivery vehicle.

279 A novel delivery system using micron-scale grape skin powder (GS

280 a highly biocompatible tumor cell-targeting delivery systems utilizing exosome-like vesicles (ELVs)

281 ce for the design of successful biomolecular delivery systems via optimizing the physicochemical prop

282 p identify areas of low coverage and vaccine delivery system vulnerabilities and can ultimately suppo

283 e present study, a prodrug-based nanocarrier delivery system was developed that exhibited high therap

284 1, for prolonged release of atenolol in drug delivery systems was investigated both experimentally, u

285 electronic medical records of an integrated delivery system, we evaluated health care costs by expen

286 In an integrated healthcare delivery system, we examined temporal trends in incident

287 e is an urgent need to develop improved drug delivery systems which have potential to cross impaired

288 in manufacturing capacity and public-sector delivery systems will be needed to prepare for product i

289 t for HS by establishing a novel intradermal delivery system with a dissolving microneedle array (DMN

290 ding alpha-tocopherol could be introduced as delivery system with favorable features under severe env

291 We sought to assess whether an exhalation delivery system with fluticasone (EDS-FLU) capable of hi

292 d its antimicrobial activity and generated a delivery system with pH-sensitivity for controlled relea

293 region of a reporter gene using a lentiviral delivery system with reduced recombination-induced sgRNA

294 adapted tool combines a programmable reagent delivery system with temperature controller and flow cel

295 a large integrated health insurance and care delivery systems with 5 study sites.

296 to equip nanocarriers of the controlled drug delivery systems with MB-based fluorescence imaging capa

297 e led to a rapidly increasing number of drug delivery systems with potential for spatiotemporally con

298 However, insulin delivery systems with rapid in vivo glucose-responsive b

299 The interaction of drug delivery systems with tissues is key for their applicati

300 Developing a cytosolic antibody delivery system would offer unique opportunities to dire