ライフサイエンスコーパス: demonstrate

1 ent and reconditioning is increasingly being demonstrated.

2 ery, bioimaging, and cell targeting was also demonstrated.

3 Diverse product utility is demonstrated.

4 ar the alkaline hydroxide-exchange layer, we demonstrate a BPM driving WD with overpotentials of <10

5 Our results demonstrate a link between pathological localisation of

6 Furthermore, we demonstrate a multigenerational enhancement of progeny s

7 In this project, we demonstrate a novel approach aimed at protecting islets

8 Our results demonstrate a novel mechanism by which cystic epithelial

9 We demonstrate a novel viral gene expression strategy to ta

10 Herein we demonstrate a packed bed flow reactor capable of achievi

11 Their results demonstrate a pH-dependent monomer-to-dimer transition,

12 We demonstrate a phase diagram for air evolution regarding

13 Finally, we demonstrate a portable and real-time POC device to detec

14 These results demonstrate a potential role of extrapyramidal plasticit

15 and a transgenic reporter assay, our results demonstrate a requirement for dnmt1 activity in the regu

16 Here we demonstrate a robust high-content imaging method for the

17 We demonstrate a strategy to improve the binding affinity o

18 These studies demonstrate a strategy to tune RNA structure-targeting c

19 For these parameters, we experimentally demonstrate a threshold in laser-to-proton conversion ef

20 esions characterized as clustered microcysts demonstrate a very low risk of malignancy and can be cla

21 We also demonstrated a hierarchical strand-displacement reaction

22 Rate-based calculations in packing column demonstrated a kinetic control with highly viscous FIL/I

23 al evaluation of a swine model of concussion demonstrated a notably similar pattern of axonal damage

24 yrosine ((18)F-FET) (7 studies, 172 lesions) demonstrated a sensitivity of 90% (95% confidence interv

25 cheal tube contents from one of our patients demonstrated a specimen consistent with sloughed tracheo

26 Here, single-cell multi-omics analysis demonstrates a shared mechanism with lymphoid malignancy

27 vironmental factors in FECD pathogenesis and demonstrates a strong link between UVA-induced estrogen

28 the antihypertrophic effect of ACC2 deletion demonstrating a causal role of elevated aspartate level

29 60,000 resolving power (at 400 m/z), and we demonstrate accurate 21-plex quantification of labeled K

30 oorer physiological state, and (3) C15:0 has demonstrated activities and efficacy that parallel assoc

31 Here, we demonstrate an electrochemical process that uses neutral

32 Our findings demonstrate an enrichment of potentially disruptive regu

33 ntial changes of core clock gene expression, demonstrating an exercise and clock interaction, providi

34 Our study demonstrates another level of regulatory complexity unde

35 However, the demonstrated approaches still require that the object is

36 n of the ACE2/Ang1-7/Mas axis and previously demonstrated benefits of lung function improvement in SA

37 22 functions in transport from the ERGIC, as demonstrated by an essential role in forming the replica

38 tral role of B cells in the disease has been demonstrated by both the robust clinical responsiveness

39 age is likely, which indeed has already been demonstrated by cardiovascular and gastrointestinal symp

40 ytes in the device were mechanosensitive (as demonstrated by changes in calcium flux under applied lu

41 iomarker of underlying amyloid pathology, as demonstrated by its strong correlation with Thal phase.

42 Hepatocellular activation of c-Jun was demonstrated by nuclear translocation of c-Jun, enhanced

43 iversity noticeably affected bird responses, demonstrated by significantly higher abundance (43%), ri

44 tivity and specificity comparable with those demonstrated by the duplex real-time PCR assay.

45 To demonstrate capabilities, the system was used to overcom

46 The gained fundamental understanding and demonstrated capabilities enable the rational design and

47 The laboratory measurements demonstrate cloud formation in mean-subsaturated conditi

48 To demonstrate computational spectroscopy, we provide our a

49 We demonstrated covalent cellulose-xyloglucan bonding in pl

50 Dp16 mice demonstrated craniofacial hypoplasia, especially in the

51 gation of USP22-regulated functions in vitro demonstrated critical roles for USP22 in prostate cancer

52 In the first, we demonstrate deep conservation of a nucleolus gene module

53 able of handling widely varying GC-bias, and demonstrating direct detection of epigenetic modificatio

54 al structure of the visual motion pathway to demonstrate dissociation in the fMRI response magnitude

55 We have demonstrated excellent performance of our universal func

56 We demonstrate for the first time the SFC-MS separation of

57 This demonstrates for the first time that PA influences the b

58 ed subjects excluding neurologic deaths also demonstrated good discrimination (all area under the rec

59 We hypothesized that cognition would demonstrate greater HC-SCZ classification accuracy and t

60 We developed a minimal mathematical model demonstrating growth factor signaling is sufficient to g

61 Furthermore, we demonstrate >1,000-fold variability in material routinel

62 enotypes and pollination time as well, which demonstrated high performance of the metabolic fingerpri

63 dition to regional ecosystem devastation, we demonstrate how 'Arctic Dimming' can explain the circump

64 We demonstrate how current economic and social systems can

65 n the field of cancer and other diseases and demonstrate how nanobiosensors could enhance the perform

66 free-ranging cheetahs (Acinonyx jubatus) to demonstrate how new insights into the socio-spatial orga

67 icroenvironments and phagocytic targets have demonstrated how altering the actomyosin cytoskeleton af

68 It has been demonstrated how process signatures from the PAT tools a

69 This study demonstrates how the costs of barrier crossings in preva

70 nt-based mechanism of enhanced cooperativity demonstrates how the widespread phenomenon of enzyme pol

71 n the sensory perception of sponge cakes and demonstrates how this approach can be used to improve th

72 Using HPV-EM, we demonstrated HPV genotypic differences in recurrence and

73 These BRD4 BD1 inhibitors demonstrated impressive in vivo efficacy and overall pro

74 We demonstrate in 1,976 subjects of a German population coh

75 Its validity was demonstrated in cellular assays and a murine colitis mod

76 Therefore, our results demonstrate irreversible oxidation of pollen proteins du

77 tion of a human rabbitized (FdltB(r)) strain demonstrated its capacity to generate a similar inflamma

78 computer flow simulation studies, this study demonstrates its effectiveness in experimental fluid mec

79 ficient ligand-based design approach adopted demonstrates its versatility in generating chemical dive

80 ell lysates, and mouse liver tissue samples, demonstrating its highly sensitive and specific glycopro

81 Implementing our protocol, we have also demonstrated late-stage olefination and alkynylation of

82 . dispar), our tetraplex real-time PCR assay demonstrated levels of sensitivity and specificity compa

83 d transgenes in any of the passaged viruses, demonstrating long-term genomic stability of complex VSV

84 Invasive lobular carcinoma (ILC) demonstrates lower conspicuity on (18)F-FDG PET than the

85 Recent studies have demonstrated new functions of individual members of the

86 with mathematical modeling, we unambiguously demonstrate no cooperativity in autophosphorylation of C

87 Examples are demonstrated of the late-stage functionalization of natu

88 Previously, we demonstrated PCSK6 upregulation in human atherosclerotic

89 Twelve-month old Aip+/- mice demonstrated phenotypic and biochemical evidence of GH e

90 We demonstrate photoswitching anisotropy FRET (psAFRET) wit

91 This BTC demonstrated potent antitumor activity in vivo but was p

92 istic regression of the retrospective cohort demonstrated predictors of infection.

93 We demonstrate QEC of an encoded qubit with suppression of

94 These results demonstrate RadAR as a reliable and valuable tool for th

95 Our results thus demonstrate rapid trait refinement and adaptation to the

96 These films demonstrate record tensile strength up to ~570 MPa for a

97 Magnetic resonance (MR) imaging studies have demonstrated reduced global and regional brain volumes i

98 , we report that mice lacking Pdcd1 (Pd1-/-) demonstrated remarkable protection against bone destruct

99 Finally, we demonstrated robust function in biomedically and industr

100 [(64)Cu]Cu-c[R(4)W(5)C] demonstrated significantly reduced uptake in the brain a

101 Batch reactor studies demonstrated substantial adsorption of PFOA and PFOS by

102 Without adaptation, the model demonstrated substantial agreement with the original rep

103 Pharmacodynamic studies demonstrated substantial inhibition of phosphorylation o

104 The CFP model demonstrated substantially superior performance to 4 oph

105 into mammary fat pad of syngeneic mice, and demonstrated synergy when combined with anti-PD-1 therap

106 We demonstrate that 2'-azidouridine is only incorporated in

107 These results demonstrate that a novel bivalent Ebola VLP vaccine elic

108 Finally, we demonstrate that a significant fraction of PSVs in segme

109 Together, our findings demonstrate that alpha2delta1 and alpha2delta3 subunits

110 We demonstrate that alphaCD3 alone induced substantial T-ce

111 We demonstrate that Anr and Mhr contribute to LasR- strain

112 Here we demonstrate that autoSTOMP can efficiently label, purify

113 actam targeting of transpeptidation, and (d) demonstrate that both substrates have to be bound before

114 These findings demonstrate that BRCA2 tumor suppressor function tolerat

115 red molecular dynamics (SMD) simulations, we demonstrate that cbEGF domain calcium binding decreases

116 We demonstrate that CERBERUS has auto-ubiquitination activi

117 Additionally, we demonstrate that chABC increases TRKB phosphorylation (p

118 Our findings demonstrate that chronic endothelial inflammation advers

119 d-scale estimates of N inputs and outputs to demonstrate that current N removal by US wetlands (about

120 We also demonstrate that cytokinin-induced protein synthesis req

121 We demonstrate that DarT(Mtb) -DarG(Mtb) form a functional

122 Here, we demonstrate that DCLK1-overexpressing primary human hepa

123 mmunoprecipitation-sequencing-based analyses demonstrate that direct readout of H3K27me3 by BAHCC1 is

124 Taken together, these data demonstrate that discrete glycan motifs expressed on CD1

125 Here, we demonstrate that DXO also catalyzes the hydrolysis of RN

126 Our findings demonstrate that environmental geometry affects human sp

127 Our results demonstrate that EWSR1 is essential for promoting PRDM9-

128 Here, we demonstrate that exonuclease 1 (EXO1) plays a key role i

129 n and anaphylaxis by engaging FcgammaRs, and demonstrate that Fc-engineered versions of the mAb could

130 We demonstrate that future observational and theoretical st

131 Using a reaction-diffusion model, we demonstrate that growth rates are inextricably coupled w

132 th an a.c. supply at household frequency, we demonstrate that hBN-SSWC is able to support an ultrahig

133 We demonstrate that heterogeneous/biphasic chemical reactio

134 Together, these results demonstrate that holo-WhiB1 regulates gene expression by

135 We demonstrate that in the lysolecithin demyelination model

136 oped carbon/RuMo nanoalloys heterostructures demonstrate that introducing N and Mo atoms into C and R

137 Experimental animal models demonstrate that maternal immune activation (MIA) elevat

138 y, and the analyses of 64 drug responses, we demonstrate that MKpLMM consistently outperforms competi

139 Here, we further demonstrate that more than ten fundamental equations, in

140 These data demonstrate that multicancer blood testing combined with

141 Here, we demonstrate that Myoglianin (Myo), an Activin family mem

142 canine, rapid atrial pacing model of AF, we demonstrate that NADPH oxidase 2 (NOX2) generated oxidat

143 We demonstrate that Notch activation in human tonsil-derive

144 Here, we demonstrate that Parkin has functions in the nucleus and

145 Using cell-specific markers, we demonstrate that pericytes rather than endothelial cells

146 We demonstrate that phosphine oxides are highly polar funct

147 We demonstrate that plasmanylethanolamine desaturase defici

148 ecently used passive joint angle matching to demonstrate that proprioception of the knee joint is ver

149 Our studies demonstrate that residual endotoxin after successful tre

150 e shell shape on strength and quantitatively demonstrate that shell strength is derived from multiple

151 These data demonstrate that simultaneous recognition of PE and PS m

152 These findings demonstrate that STAT1 signaling and CD8 T cells concomi

153 We thus demonstrate that structural systems biology enables a pr

154 These results demonstrate that sustained physiologic hyperglycemia for

155 Our findings demonstrate that systemic K(ATP) channel inhibition redu

156 Our results demonstrate that targeting FPR1 by a selective small mol

157 g reconstructions of summer soil moisture to demonstrate that the 2000-2018 SWNA drought was the seco

158 tion isotherms and guest displacement assays demonstrate that the adsorbed cages retain the ability t

159 We demonstrate that the biomarkers do not show significant

160 The results demonstrate that the capacity for rapid Na(+)-based sign

161 Using Cbf1p and MAX, we demonstrate that the CCRA method is able to detect small

162 Together, these results demonstrate that the CTK complex is negative regulator o

163 Here, we demonstrate that the deubiquitinase Cyld prevents excess

164 Our data demonstrate that the Foxp3 locus can be epigenetically e

165 to compensate for this instability, and then demonstrate that the instability has been suppressed.

166 We demonstrate that the intestinal microbiome contributes t

167 We demonstrate that the plasticity rules depend highly on t

168 long with spectroscopic characterization, we demonstrate that the probe improves quality and conditio

169 Here, we demonstrate that the RarA protein makes a major enzymati

170 Here, we demonstrate that the Ras->Raf->rho kinase (ROCK) pathway

171 In this study, we demonstrate that the shedding of syndecan-1 by MMP-3 and

172 ettling from surface accumulations; here, we demonstrate that the spatial distribution and ultimate f

173 ta from patients with focal brain damage, we demonstrate that there is a strong psychometric correspo

174 We now demonstrate that these organic salts, specifically azeti

175 Furthermore, we also demonstrate that this method can be used for the prepara

176 We demonstrate that this method is suited to both 3D struct

177 ining a central benzothiadiazole(10) unit to demonstrate that this strategy can be used to create hig

178 We further demonstrate that treatment with radiation and polyinosin

179 We also demonstrate that two copies of the catalytic module of p

180 We demonstrate that ULM microbubble data processing methods

181 We demonstrate that under conditions of increased chromosom

182 Our data demonstrate that, even after removal of the primary tumo

183 Here we demonstrate that, in regions of high exchange energy den

184 Our in vivo studies demonstrated that (a) infants (<18 months) had higher vi

185 In vitro and in vivo studies demonstrated that 20 restored the activity of beta-lacta

186 We previously demonstrated that a sharp drop in Tie2 expression observ

187 sitive dyes, Di-4-ANEPPDHQ and C-laurdan, we demonstrated that AdipoRon decreased the rigidity of the

188 We first demonstrated that alpha(2)M* induced trophoblastic cell

189 Our recent work demonstrated that B2 RNA binds stress genes to retard tr

190 We have previously demonstrated that both GLP-1 and CCK are produced in the

191 Several randomized trials demonstrated that chemoprophylaxis, or low-dose anticoag

192 We recently demonstrated that DspB has increased catalytic activity

193 in High Cardiovascular Risk Subjects) trial demonstrated that evolocumab added to a background stati

194 Last, we demonstrated that genetic induction of lipid cacostasis

195 47 and the CSE inhibitor DL-propargylglycine demonstrated that H(2)S is the effector molecule regulat

196 tumors from colon cancer patients, our data demonstrated that HT-DBP could be used to generate perso

197 We recently demonstrated that increased expression of the stress res

198 Exomic studies have demonstrated that innate immune genes exhibit an even hi

199 Dye-loaded particles demonstrated that intracellular delivery was achieved in

200 Previous studies demonstrated that loss of function of ANK or ENPP1 (redu

201 Our results demonstrated that miR-1291 was effective to sensitize PC

202 Herein, it is demonstrated that mixed-valent Cu acts as an effective d

203 y drug substance with low levels of HCPs, we demonstrated that our method could detect HCP with low m

204 Corrected post-hoc analyses demonstrated that patients had significant enlargement o

205 ction between basal ganglia and thalamus, we demonstrated that patients with current history presente

206 The results demonstrated that protein synthesis was modulated to fac

207 Most importantly, our study demonstrated that protein tissue-enrichment information

208 le genome sequencing of select transformants demonstrated that recombination of up to 56.7 kbp length

209 The MRI images demonstrated that side positioning gives better contact

210 Prior studies have demonstrated that surgeons with lower peer-reviewed rati

211 Recent evidence has demonstrated that tau oligomers, small and soluble prefi

212 These Phase 3 studies demonstrated that the brolucizumab q12-week regimen main

213 DNA and cDNA 16S rRNA gene profiling demonstrated that the microbial community was dominated

214 k of other LRR protein complexes, we further demonstrated that the present approach may be broadly ap

215 Contrary to this notion, we have recently demonstrated that these defective proviruses are not sil

216 Reporter assays demonstrated that these LTR12C elements drive gene expre

217 re predicted to be benign, in vitro modeling demonstrated that these mutations conferred increased mi

218 Our previous study demonstrated that Toll-like receptor 7 (TLR7) is essenti

219 and selection for G418 resistant genomes, we demonstrated that Y138 is a critical residue for Brd4 as

220 It was demonstrated that: (1) mature lianas invested proportion

221 Our study demonstrates that AP-2-dependent internalization of PM p

222 active/toxic compounds (ouabain and CdCl(2)) demonstrates that cellular reactivity can be boosted by

223 icillin as well defined test cases, our work demonstrates that drug-target binding is a major predict

224 Therefore, this work demonstrates that dynamic crowding nontrivially alters t

225 The latest research demonstrates that in the nucleus accumbens, opioid-induc

226 Our work demonstrates that in trans paired nicking retains target

227 Our work demonstrates that individual differences in behaviour ex

228 This research demonstrates that partisan meta-perceptions are subject

229 trafast dipole moment reorientation dynamics demonstrates that refocusing of the diffusive light is b

230 tions of the IC from Chaetomium thermophilum demonstrates that the H2 region of C. thermophilum IC ha

231 The benchmark analyses demonstrates that the spectrum of the polymer non-backtr

232 l data, there is no neurobiological evidence demonstrating that cannabinoids can also alter the brain

233 g capabilities are taxonomically widespread, demonstrating that freely interacting animals (whether w

234 -induced rhodopsin signaling like wild type, demonstrating that in vivo monomeric arrestin-1 is neces

235 years there has been a preponderance of data demonstrating that opioids are overprescribed after surg

236 MMP1 expression required both AHR and ARNT, demonstrating that the AHR-ARNT transcriptional complex

237 sted, and lesion areas identified as active, demonstrating that thermal imaging is a promising approa

238 is of sinonasal mucociliary differentiation, demonstrating that transcriptome related to ciliogenesis

239 c evidence and increased cell concentrations demonstrate the activity of acetate-degrading hypertherm

240 This is the first study to demonstrate the applicability of an untargeted, activity

241 Here, we demonstrate the applicability of the integration of a de

242 Here, we demonstrate the application of this method in a fast ult

243 sing it as mechanically stable anchorage, we demonstrate the applications in single-molecule manipula

244 Furthermore, we demonstrate the capabilities of the detector for the stu

245 Furthermore, we demonstrate the correlation between myocardial energetic

246 These data demonstrate the diversity of potential outcomes followin

247 We demonstrate the dual-targeted delivery and enhanced ther

248 ay of simulated and experimental datasets to demonstrate the effectiveness of GPseudoClust in a range

249 These results demonstrate the existence of two previously unidentified

250 To demonstrate the feasibility of this approach, we have us

251 pragmatic interventions and simple aims, we demonstrate the feasibility, acceptability, and cost sav

252 We demonstrate the growth of single-crystal layers of hexag

253 ing sites for substrate K(+) and Cl(-) ions, demonstrate the importance of key coordinating residues

254 demonstrate the importance of neutrophil extracellular t

255 onds as electron reservoirs is introduced to demonstrate the new concept of "structronics" (a neologi

256 eveloped using the closure of the algebra to demonstrate the parallel information processing at the l

257 Moreover, we demonstrate the potential for multiplexing using a digit

258 licity and appended recognition elements, we demonstrate the potential of the 2-sulfonylpyridine reac

259 We demonstrate the power of this approach for detection app

260 Kinetic studies also demonstrate the requirement for sustained PI supply from

261 ium species and comparison with kinetic data demonstrate the significance of 1,5-O...Ch interactions

262 Here we demonstrate the successful application of femtosecond st

263 Further transformations to demonstrate the utility of these scaffolds were also inv

264 We demonstrate the utility of this transformation by aminat

265 Results: We demonstrated the ability to scan for a shorter duration

266 Our findings convincingly demonstrated the applicability of our developed SWSP sen

267 We demonstrated the application by first measuring and then

268 proficient peroxidase, C45, we have recently demonstrated the catalytic potential of simple, de novo-

269 Our findings demonstrated the effectiveness of P-Tris affinity nanofi

270 A prior pilot study demonstrated the systemic absorption of 4 sunscreen acti

271 ng FT-MS data from a soil microbiology study demonstrates the core functionality of the package and h

272 The recent progress not only demonstrates the diversity of scientific areas in which

273 This pilot study in healthy volunteers demonstrates the feasibility of obtaining reliable MTR m

274 This paper thus demonstrates the importance of an intact alcove in formi

275 Our study demonstrates the need for a combination of biosystematic

276 Together, our study demonstrates the use of iterative "perturb and observe"

277 This study demonstrates the use of ML as a viable strategy to enabl

278 om cell cultures and human AD brain tissues, demonstrating the ability of the Hsp70 machinery to reco

279 , ecology, behaviour and life history, while demonstrating the importance of demographic-dependent se

280 ies considerably between pancreatic centers, demonstrating the potential benefit of quality assurance

281 s and ungulates to an apex predator, further demonstrating the potential effects of changing climates

282 e highly susceptible to S aureus infections, demonstrating the relevance of CD163 for antimicrobial d

283 of the HHV-6A and HHV-6B integration locus, demonstrating the utility of optical mapping for the ana

284 nificant manual interventions or have yet to demonstrate their utility in large datasets.

285 or preparing amorphous Pd nanomaterials, and demonstrates their promising electrocatalytic applicatio

286 e and after correction of the CFTR mutation, demonstrating their future potential for disease modelin

287 First, we demonstrated through both PCR and immunostaining that mo

288 ly simple chromatographic separation that is demonstrated to be applicable to a variety of block copo

289 eoblast models, the identified mutations are demonstrated to exert a gain-of-function mechanism, augm

290 functionalized with a dodecanoate group were demonstrated to store thermal energy in their metastable

291 Here, we demonstrate translational read-through across two evolut

292 Survival analysis demonstrated treatment success in 70%, 45%, and 27% of e

293 We demonstrate unequivocally that Katanin phosphorylation a

294 agent (phospholipid-polyethylene glycol), is demonstrated using standard cytotoxicity assays.

295 the intermediate state KCNQ1 conductance is demonstrated using voltage-clamp fluorometry.

296 ition, strong in-plane optical anisotropy is demonstrated via polarized Raman spectroscopy and second

297 RT-qPCR demonstrated viral replication in salmon brains up to 15

298 Concordantly, we demonstrate Vpr-dependent rescue of HIV-1 replication in

299 We demonstrate which stages of the approach can extract mea

300 Our findings demonstrate widespread pleiotropy and offer further insi