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1 dendron, which is equivalent to generation 5 dendrimer.
2 he compactness of the periphery of the G8-OH dendrimer.
3 he hybrid hydrogenated-fluorinated RHF Janus dendrimer.
4 ase of the number of sulfamoyl groups in the dendrimer.
5 p to 27 leaving groups in a third-generation dendrimer.
6 a concept of an information-coded 2D digital dendrimer.
7 of the azide groups at the periphery of the dendrimer.
8 eased liver and spleen uptake compared to G4 dendrimers.
9 high affinity for DNA possessed by cationic dendrimers.
10 were also coassembled with hybrid RHF Janus dendrimers.
11 ent attachment of Cy5-Trolox conjugates onto dendrimers.
12 of a wide range of novel, dense, and chiral dendrimers.
13 accomplish sequence-controlled heterolayered dendrimers.
14 even vary depending on the generation of the dendrimers.
15 nd silver), various other nanomaterials, and dendrimers.
16 nsional order analogous to that of molecular dendrimers.
17 on 4, hydroxyl-functionalized polyamidoamine dendrimers.
18 Lewis X antibodies (aSlex)-conjugated PAMAM dendrimers.
19 oated with polypyrrole (PPy) and redox PAMAM dendrimers.
20 ngements of the 0- and 1-bits in the uniform dendrimers.
21 s into the potential clinical translation of dendrimers.
23 ations and thus successfully converts non-LC dendrimers (1a and 1b) into LC dendrimers (2a and 2b).
30 predict the intravenous pharmacokinetics of dendrimers, a commonly explored drug vector, based on ph
32 bed new types of carriers termed amphiphilic dendrimers (ADs), which are based on polyamidoamine dend
34 ummarizes the stepwise evolution of peptidic dendrimers along with their multifaceted applications in
38 the high data storage capacity of a uniform dendrimer and uncovers good opportunities for the digita
41 rgent iterative methods for the synthesis of dendrimers and dendrons containing ethylenediamine (EDA)
43 ontaining sequence-defined amphiphilic Janus dendrimers and either linear or branched oligosaccharide
45 investigate 3rd-6th generation (G3-G6) PAMAM dendrimers and GrO with different levels of oxidation.
47 ticles (Pd, Pt, Rh) stabilized by G4OH PAMAM dendrimers and supported in SBA-15 (MNPs/SBA-15 with M =
48 liposomes, virosomes, virus-like particles, dendrimers and the like, plus macromolecular drugs, anti
49 itic effect can be observed with any type of dendrimer, and for any type of property, even if it has
50 to the density of functional groups on each dendrimer, and insensitive to factors that promote or in
56 phenylphosphonium ion, and G0 polyamidoamine dendrimer are tested for their ability to inhibit the he
57 nylmethane-ethynylene-based shape-persistent dendrimers are a new class of nanoobjects with an intrig
61 erminal functionality, where the majority of dendrimers are directed to the endo-lysosomal compartmen
65 hemically-controlled branched architectures, dendrimers are ideally suited for these initial steps, s
67 chnique was achieved by employing Fe3O4@SiO2-dendrimer as immunosensing platform and PAMAM as the car
68 ymers are a suitable alternative for perfect dendrimers as building blocks for dendritic nanocarrier
69 tention to critically evaluate the status of dendrimers as drug carriers and find answers as to why t
72 4/IL-4Ralpha-targeting peptide with G5 PAMAM dendrimers as the loading surface and can convey therape
74 de here a protocol for the synthesis of this dendrimer, as well as siRNA delivery to immune cells suc
75 D-aptamer) used as detection probe and PAMAM-Dendrimers/AuNPs was used for covalent attachment of CA1
76 endrimers (PPDs) represent a unique class of dendrimers based on their rigid, shape persistent chemic
77 diagnosis based on the combination of novel dendrimer-based conjugates and a recently developed nano
78 re, we report the development of theranostic dendrimer-based lipid nanoparticle (DLNP) system contain
81 a novel compact nanoplasmonic platform and a dendrimer-based strategy provides a highly sensitive lab
83 have used neutral high-generation phosphorus dendrimers bearing 48 (G3) or 96 (G4) bisphosphonate gro
84 ings can potentially alter the perception of dendrimers being limited to carriers to being prodrugs f
86 self-organize from supramolecular spheres of dendrimers, block copolymers, surfactants and other self
88 ee-dimensional crystals of protein cages and dendrimers, by adsorbing proteins to the surface of mate
89 sicles self-assembled from amphiphilic Janus dendrimers, called dendrimersomes, encapsulate high conc
90 Here we show that the surface-functionalized dendrimers can be sequentially coated with two antibodie
92 Exposure to low dosages of polyamidoamine dendrimer carbon nanotubes (PAMAM-CNTs) did not affect T
96 ed using atomic force microscopy reveal that dendrimer-coated surfaces exhibit an order of magnitude
99 nd regulating HT29 cells by the aSlex-coated dendrimer conjugate were analyzed by microscopy and flow
100 m is ultimately expected to be used to guide dendrimer construct design and refinement prior to embar
101 The iterative synthetic protocols used for dendrimer construction were developed based on the desir
103 endrons (RH), while one denoted hybrid Janus dendrimer, contains a combination of chiral-racemic fluo
106 ion (measured by drug CSF/serum level) of G6 dendrimers correlated with the severity of neuroinflamma
107 tra-amniotically administered hydroxyl PAMAM dendrimers could be an effective drug delivery vehicle f
111 g systemic administration of the Cy5-labeled dendrimer (D-Cy5), we demonstrate dendrimer uptake in ce
112 ed to hydroxyl terminated generation-4 PAMAM dendrimer (D-Sino) as a potential therapy for attenuatin
113 cluding decacyclene- and perylene-containing dendrimer D6, in which two types of polyimide dyes are p
114 Four generations of poly(amidoamine) (PAMAM) dendrimers decorated with benzenesulfonamide moieties we
115 tribution of scFv7F9Cys after conjugation to dendrimers decreased 45 and 1.6-fold respectively, and t
117 w of the most recent synthetic strategies in dendrimer design will be presented for the purpose of co
118 iphenylphosphonium ion and G0 polyamidoamine dendrimer, despite being positively charged, interact pr
119 Herein, as a proof-of-concept, a family of dendrimers displaying internally queued disulfide bridge
120 rease with the increased generation of siRNA dendrimers due to a high charge density and structural f
122 , combined with prolonged circulation of the dendrimer, enabled administration of an efficacious dose
123 For improve the sensitivity, polyamidoamine dendrimer-encapsulated gold nanoparticles (AuNPs-PAMAM)
124 in layer of ALD Al2O3 and an overlayer of Pt dendrimer-encapsulated nanoparticles (DENs) have been in
125 , however, be reactivated by immobilizing Pt dendrimer-encapsulated nanoparticles (DENs), containing
126 iated endocytotic mechanism, irrespective of dendrimer end-terminal functionality, where the majority
127 effects observed with polyphosphorhydrazone dendrimers, even if many examples obtained with other ty
132 disease, the chronic administration of such dendrimers for 5 days led to a much more efficient drop
135 n the injured brain compared to generation 4 dendrimers (G4, 4.3nm), which were undetectable in the b
136 ation, hydroxyl-terminated, poly(amidoamine) dendrimers (G6-OH DENs) having diameters of approximatel
137 ting ligands conjugated to amphiphilic Janus dendrimers generates dendrimersomes that selectively dis
140 al growth (DP=2(n) -1) or double exponential dendrimer growth approaches (DP=22n -1) with significant
141 tive electrophysiology showed that alpha-ImI dendrimers had approximately 100-fold enhanced potency a
142 confirmed that each alpha-ImI moiety in the dendrimers had the same 3D structure as native alpha-ImI
143 ontaining a new, click-synthesized porphyrin dendrimer has been used to map oxygenation across an ex
144 mbly phenomenon of this class of amphiphilic dendrimers has not been molecularly explored using molec
147 numerous examples, two families of inorganic dendrimers have emerged as particularly promising: silic
149 e data suggest that neutral G3-G4 phosphorus dendrimers have strong potential applications in the the
150 Peptide dendrimers, unlike other classes of dendrimers, have immense applications in biomedical rese
152 e groups are deemed one of the advantages of dendrimers; however, only small amounts of drugs can be
154 d that attachment of a fifth-generation (G5) dendrimer (i.e., cloaking) to the widely used 4-methoxy-
155 ocol requires simple mixing of the siRNA and dendrimer in buffer, with subsequent application to the
158 play the main properties of both families of dendrimers in the fields of catalysis, materials and bio
160 -yielding synthesis of a series of polyimide dendrimers, including decacyclene- and perylene-containi
165 f Nanomaterials) to reveal real-time protein-dendrimer interactions using a systems biology approach.
166 y TITAN in a detailed temporal manner during dendrimer internalization, traceable to at least two maj
167 the stoichiometry of the fluorophore to the dendrimer is 1:1, we were able to directly compare uptak
168 torage capacity of non-linear binary digital dendrimer is established based on data matrix barcode, g
169 errin-bearing generation 3 polypropylenimine dendrimer is therefore a highly promising delivery syste
172 differently when it is alone or linked to a dendrimer; its properties can even vary depending on the
174 sicles self-assembled from amphiphilic Janus dendrimers, known as dendrimersomes, are comparable.
175 d that the conjugation of lactoferrin to the dendrimer led to an enhanced DNA uptake by 2.1-fold in b
177 fect of chemically modified phytoglycogen, a dendrimer-like alpha-d-glucan nanoparticle, on dendritic
178 (6)-10(7) were determined between nanometric dendrimer-like ligands and the rod-shaped micrometric ba
179 ms, e.g., polymers, nanoparticles, micelles, dendrimers, liposomes, polyplexes, and virus-like-partic
180 ed to detect RCC-CTCs through integration of dendrimer-mediated multivalent binding, a mixture of ant
182 ding on the tissue source and cell type; the dendrimer-mediated siRNA delivery; and subsequent functi
183 Notably, the triggered release mechanism of dendrimer-mediated triptolide delivery significantly red
185 rticles, polymer-coated metal nanoparticles, dendrimers, micelles and star polymers to impart nitric
186 40-atom rhodium (Rh) NPs, encapsulated by dendrimer molecules and supported in mesoporous silica,
187 systemic administration of a single dose of dendrimer-N-acetyl cysteine conjugate (D-NAC) at either
189 gold nanoparticles-poly(amidoamine) (PAMAM) dendrimer nanocomposite (3D-Au-PAMAM) covalently immobil
190 ultichromophoric probes based on fluorescent dendrimer nanoconjugates (FDNs) was developed for single
191 ts the glyco-conjugate: organic macrocycles, dendrimers, nanomaterials, and polymers are considered.
192 ivered using a targeted, systemic, maternal, dendrimer nanoparticle (DNAC), in a mouse model of intra
193 the presence of pentobarbital increased the dendrimer nanoparticle uptake significantly ( 2-fold bot
194 fully synthetic, single-dose, adjuvant-free dendrimer nanoparticle vaccine platform wherein antigens
196 activate microglia, the increased uptake of dendrimer nanoparticles in their presence can be exploit
198 e by conjugating multiple anti-METH scFvs to dendrimer nanoparticles, extending the scFv half-life fr
200 he mode of uptake, trafficking and safety of dendrimers of different end-terminal functionality (carb
201 ic self-assembly of cationic polyelectrolyte dendrimers of different generations and oppositely charg
202 The MWCNTs-PPy layer was modified with PAMAM dendrimers of fourth generation (PAMAM G4) with covalent
206 on with a fourth-generation poly(amidoamine) dendrimer (PAMAM(G4)) on gold surface for the immobilisa
208 s particularly promising: silicon-containing dendrimers, particularly carbosilanes, and phosphorus-co
212 y curated the largest relational database of dendrimer pharmacokinetic parameters and their structura
214 cribe a "double-punch" strategy by combining dendrimer platform and injectable hydrogel encapsulation
215 ddress this, we used a GnRH peptide-modified dendrimer platform with and without lipidation strategy.
217 and polymer-small-molecule drug conjugates, dendrimers, polymer nanoparticles and multifunctional sy
218 monium, chemically diverse cations including dendrimers, polyvalent metals, metal complexes, amphiphi
221 rich ssDNA(S1) immobilized on the Fe3O4@SiO2/dendrimers/QDs and AuNPs modified with complementary apt
222 ergy transfer (ECL-RET) approach, Fe3O4@SiO2/dendrimers/QDs exhibited amplified ECL emissions (switch
223 er antigen 125 (CA 125) using polyamidoamine dendrimer-quantum dots (PAMAM-QDs) and PAMAM-sulfanilic
224 zed with either citrate or by low-generation dendrimers rapidly grow during electrocatalytic reductio
228 geting ligand to the surface of pre-existing dendrimers results in poorly-defined compound mixtures t
229 d from a combination of a small RNA with the dendrimer's own negligible toxicity, therefore illuminat
230 njugated to the surface without altering the dendrimer's performance, for example its solubility.
232 ylcholine-detecting nanosensors based on DNA dendrimer scaffolds that incorporate butyrylcholinestera
233 bilization of ferrocene cored polyamidiamine dendrimers second generation (Fc-PAMAM (G2)), after whic
235 eres from short helical stacks of crown-like dendrimers self-organize a Pm3 n cubic (Frank-Kasper A15
236 bilized redox center (ferrocene) cored PAMAM dendrimers served as a layer for the further binding of
237 sent data indicating that neutral phosphorus dendrimers show impressive antiinflammatory activities b
240 approach also circumvents the nonideality of dendrimers, since the heteroleptic, one-step, spontaneou
243 ea is relatively underexplored, make peptide dendrimers sought-after candidates for various applicati
245 perties to polyvalent engagement between the dendrimer surface groups, and a potential "rolling" effe
247 ssed and challenged are the current state of dendrimer synthesis, for example the importance for surf
251 describe the use of a generation 5 l-lysine dendrimer that has been part-modified with a polyoxazoli
252 We have recently developed an amphiphilic dendrimer that is able to deliver siRNA to a variety of
253 r SN-38 conjugated to polyoxazoline-modified dendrimer that maximised efficacy and minimised adverse
254 s this issue by reporting modular degradable dendrimers that achieve the required combination of high
255 reak the hydrophobic stereotype, and provide dendrimers that can be synthetically tuned to be used in
259 xylic acid- and pyrrolidone-terminated PAMAM dendrimers through determination of cell membrane integr
262 ols in all living cells, the collapse of the dendrimers to a multitude of smaller thiols was intracel
264 lation of the dendritic central linker leads dendrimers to possess more isomeric conformations and th
265 s of the utilitarian macromolecules known as dendrimers today, our first examples employed predesigne
266 In an orthotopic model of glioblastoma, dendrimer-triptolide achieved significantly improved ame
270 shed by the inhibitory effect of dynasore on dendrimer uptake and changes in temporal profiles of key
271 y5-labeled dendrimer (D-Cy5), we demonstrate dendrimer uptake in cells involved in ischemic injury, a
275 re are only a handful of examples of protein dendrimers; we believe that these limited examples will
276 ed 'anionic' (D-COOH) Polyamidoamine (PAMAM) dendrimers were absorbed by fetuses and demonstrated bi-
278 essful, and the resulting carboxy-terminated dendrimers were analyzed by NMR and DOSY experiments.
279 , 809 interacting proteins cross-linked with dendrimers were determined by TITAN in a detailed tempor
281 al poly(amido amine) and poly(propylenimine) dendrimers were substituted with alkyl chains of increas
285 PSA (anti-PSA) was covalently immobilized on dendrimers which were attached onto the modified Au surf
286 on, a dodecaiodo-terminated first generation dendrimer, which was transformed by another Sonogashira
287 owth is now demonstrated as a route to metal dendrimers, which are hierarchically branched nanocrysta
288 Unexpectedly, these oligoMan-containing dendrimers, which have their hydrophobic linker connecte
289 ff-rate kinetics compared to surface without dendrimers, which translated into cell capture improveme
290 ared by derivatizing the amino groups of the dendrimer with 4-carboxy-benzenesulfonamide functionalit
291 nthesis was observed at generation 4 for the dendrimer with an EDA core and at generation 5 for the o
292 into a methoxy-terminated second generation dendrimer with persistent globular shape and well-define
293 is of generation-4 poly-(amidoamine) (PAMAM) dendrimers with a precisely core positioned single sulfo
294 excited-state dynamics in organic conjugated dendrimers with atomistic resolution, a phenomenon expec
295 cient and controlled convergent synthesis of dendrimers with different sizes and shapes and multivale
297 argeting of intra-amniotically administrated dendrimers with neutral/anionic surface functionality.
298 to an intermediate layer of a polyamidoamine dendrimer, with an ethylenediamine core from the fourth
299 development of flawless structures, such as dendrimers, with unprecedented structure-to-property cap
300 ion 3-diaminobutyric polypropylenimine (DAB) dendrimer would allow the transport of plasmid DNA to th