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2 experiments we show that vinculin can bundle dendritic actin networks through rapid binding and filam
3 a metal anode has been primarily hindered by dendritic and "dead" Na formation that leads to low Coul
4 perisynaptic GluD1 labeling at putative axo-dendritic and axo-spinous glutamatergic synapses, and in
5 in the adult retina, with significantly less dendritic and axon terminal labeling in TRPM1 knockout c
6 We propose that delta-catenin regulates the dendritic arbor by coordinating the dynamics of individu
13 well as adult stages for maintaining normal dendritic arborization and sensory function to regulate
16 How neuronal growth control programs tune dendritic arborization to ensure function is still not f
17 endrite self-avoidance, synapse development, dendritic arborization, spine maturation, and prevention
19 numerous short dendrites that formed a dense dendritic arborization; they also exhibited a very dense
21 f retinal amacrine cells that do not develop dendritic arbors in relation to the spatial positioning
22 is known about the postnatal development of dendritic arbors of cortical pyramidal neurons and the i
23 results in DG granule cells with simplified dendritic arbors, reduced dendritic spine density, and d
24 romotes the stabilization of DG granule cell dendritic arbors, spines, and synapses, whereas it restr
27 GFD delivered intraventricularly to preserve dendritic architecture, reduce stroke-induced brain dama
28 cinergic cells were smaller in soma size and dendritic area, but over ten-fold more numerous than D-s
29 mination of neuronal morphology demonstrated dendritic atrophy and dendritic spine loss in dorsal str
32 rs: (1) the location of the input within the dendritic branch (proximal vs distal), (2) the strength
34 sis posits that synapse formation stabilizes dendritic branches, but this hypothesis has not been cau
35 weeks, adult-born neurons gained additional dendritic branches, formed a second primary dendrite, ac
36 treatment was associated with greater apical dendritic branching complexity, spine density, and inhib
38 , this cell type modulates the extent of its dendritic branching when faced with a variable number of
39 by which TDP-43 dysfunction interferes with dendritic branching, and may define pathways for therape
40 pyramidal neurons in the ACC did not exhibit dendritic Ca(2+) spikes as prominently found in the apic
41 pute and validate transfer functions between dendritic calcium signals of specific neurons and vascul
42 Development and function of conventional dendritic cell (cDC) subsets, cDC1 and cDC2, depend on t
43 e most strongly enriched in AD, and we found dendritic cell (CLEC7A, amphiregulin/AREG, EREG) and mac
44 lopment, only one contributed to intrathymic dendritic cell (DC) differentiation, predominantly of pl
54 s can recognize and eliminate the follicular dendritic cell (FDC) reservoir of HIV-bound immune compl
55 is currently much interest in how different dendritic cell and macrophage populations contribute to
56 CD38 as a critical regulator of plasmacytoid dendritic cell function in response to influenza virus.
57 show in this study that conventional type 1 dendritic cell IL-27 production in the draining lymph no
58 otch signaling in CD8(+) T cell responses to dendritic cell immunization, Listeria infection, and vir
59 vorinostat (VOR) and AGS-004, an autologous dendritic cell immunotherapeutic, on the HIV reservoir.
62 lymphoid cells (ILC2s) and monocyte-derived dendritic cell numbers in the mediastinal lymph nodes, a
65 (-/-) mice lacking the CD103(+) conventional dendritic cell type 1 (cDC1) subpopulation important for
66 G9Calpha(-/-)CD8(+) T-cell cytotoxicity and dendritic cell-induced proliferation, they failed to suf
67 d was able to 1) inhibit bone marrow-derived dendritic cell-mediated T cell functions and reduce seru
68 systemic increase of cf-mt-DNA that promotes dendritic cell-mediated, age-specific inflammatory respo
71 ive changes in vasculature and maturation of dendritic-cell subsets with chronicity, with FOXK1 actin
73 firmed increased frequencies of conventional dendritic cells (3.1% versus 2.1%; P = 0.023) and CD4 TN
75 F8(+) type 1 and IRF4(+) type 2 conventional dendritic cells (cDC1s and cDC2s, respectively) is well
77 ndicates Batf3-dependent conventional type 1 dendritic cells (cDC1s) rarely found within the tumor my
78 ther myeloid subsets, including conventional dendritic cells (cDCs) and monocyte (MO) subsets, expres
79 ty by acting as danger signals recognized by dendritic cells (DC) facilitating the establishment of a
82 re-associated DNA damages that are sensed by dendritic cells (DCs) and activates the host cytosolic D
83 receptor (TLR) recruitment to phagosomes in dendritic cells (DCs) and downstream TLR signaling are e
85 We show that NVP was readily taken up by dendritic cells (DCs) and promoted DC maturation and ant
91 aive CD4 T cells were primed via antigen and dendritic cells (DCs) at fever temperatures, the Th2 swi
93 hat accessible DNA elements in skin-resident dendritic cells (DCs) exhibit the highest enrichment of
94 ined.Objectives: To examine the role of lung dendritic cells (DCs) in T follicular helper (Tfh)-cell
101 monocytes, resident tissue macrophages, and dendritic cells (DCs) present in every tissue in the bod
102 mast cells (MCs) were studied; in addition, dendritic cells (DCs) purified from the draining lymph n
103 -cell lung cancers, we identify a cluster of dendritic cells (DCs) that we name 'mature DCs enriched
104 ntima is thought to be populated by vascular dendritic cells (DCs) that, during hypercholesterolemia,
105 ent upon NFkappaB-p65 and IL-6 expression in dendritic cells (DCs), as well as aryl hydrocarbon recep
106 mphocytes (CTLs) and CD103+ cross-presenting dendritic cells (DCs), as well as up-regulation of MHC c
107 absence of SIGN-R1(+) macrophages, DCIR2(+) dendritic cells (DCs), which play a key role in priming
112 and B. licheniformis Monocytes and immature dendritic cells (iDCs) responded differentially to the P
113 mmune responses in mouse bone marrow-derived dendritic cells (mBMDCs) and a synergistic response in b
115 , CD8 T, B, and NK cells, monocytes, myeloid dendritic cells (mDCs), and plasmacytoid dendritic cells
116 up by a population of IRF4+ dermal migratory dendritic cells (migDC2) that similarly upregulate surfa
118 alters TLR7-MyD88 signaling in plasmacytoid dendritic cells (pDCs) and blunts systemic production of
120 oid dendritic cells (mDCs), and plasmacytoid dendritic cells (pDCs) from three individuals with ZIKV
124 que lungs include the influx of plasmacytoid dendritic cells (pDCs), an Interferon (IFN)-responsive m
127 y and detect couplings between monocytes and dendritic cells and between erythrocytes and basophils t
128 subpopulations of ductal cells, macrophages, dendritic cells and cancer cells have spatially restrict
130 APCs, resulting in an 11.5-fold increase of dendritic cells and infiltration of lymphocytes througho
132 ss both mMHCII antigen presentation in mouse dendritic cells and MHCII-dependent CD4(+) T cell activa
133 Antigen-presenting cells (APCs) including dendritic cells and monocytes instruct naive T cells to
134 d the frequencies and activation profiles of dendritic cells and monocytes present in the blood and l
135 bers of the microbiota regulate plasmacytoid dendritic cells and monocytes via TLR7 and MyD88 signali
137 umor cell-derived lactate activates GPR81 in dendritic cells and prevents presentation of tumor-speci
138 esponses in the lungs that is independent of dendritic cells and T-cell priming in the draining lymph
139 ection in mice, with increased maturation of dendritic cells and the induction of protective CD8(+) T
140 ls have sustained contacts with intratumoral dendritic cells and tumor targets compared with low-avid
142 d systemic lupus erythematosus, plasmacytoid dendritic cells are not effector cells, have lost capaci
146 e factors associated with TNBC, whereas CD83 dendritic cells in the ALNs(-) were associated with the
147 d monocytes rapidly replaced macrophages and dendritic cells in tumors following administration of an
149 kin fibroblasts or mouse bone marrow-derived dendritic cells infected with the protozoan parasite Tox
150 re observed in most CD11c(+)CD103(+) myeloid dendritic cells migrating to mediastinal draining lymph
151 ponses to cancer and virally-infected cells, dendritic cells must capture antigens present in tissues
153 remodeling of light and dark zone follicular dendritic cells required CXCL12-dependent crosstalk with
154 d for the development of conventional type 1 dendritic cells that are essential for cross-presentatio
155 1 (LYVE-1) mediates the docking and entry of dendritic cells to lymphatic vessels through selective a
156 preceded by poor activation of conventional dendritic cells type 2 (cDC2) due to reduced type 1 inte
157 ization efficacy by targeting and activating dendritic cells via C-type lectin receptors and reduce s
159 D56(dim) natural killer cells, monocytes and dendritic cells were not reduced in number and hence rel
161 ifying a potential role for PD-L1 expressing dendritic cells within the lymph node in regulation of a
162 fessional' phagocytes (such as monocytes and dendritic cells) and 'non-professional' phagocytes, such
163 itors, monocytes, macrophages, and classical dendritic cells) are controlled by signals from the M-CS
164 und that histologic grade, intratumoral S100 dendritic cells, and CD8 T lymphocytes and CD57 natural
166 late both iNKT-mediated activation of thymic dendritic cells, and iNKT availability in extrathymic si
168 l responses of human monocytes, macrophages, dendritic cells, and neutrophils in response to stimulat
169 c cellular sources, rather than plasmacytoid dendritic cells, are responsible for interferon producti
170 nts and in their dependence on B7-expressing dendritic cells, B cells, and thymic epithelial cells.
173 We also find that monocytes, neutrophils, dendritic cells, natural killer cells, innate lymphoid c
174 of six CBMPs containing regulatory T cells, dendritic cells, or macrophages; patient selection and i
175 D8 T cells, as they have natural tropism for dendritic cells, preeminent inducers of CD8 T cell immun
176 hritis), mainly inflammatory macrophages and dendritic cells, were characterized by co-expression of
177 ing that IL-36 acts directly on plasmacytoid dendritic cells, where it potentiates toll-like receptor
178 edullary thymic epithelial cells (mTECs) and dendritic cells, whereas TRP1 expression was restricted
179 ily, is the prototypic endocytic receptor of dendritic cells, whose ligands include phosphorothioated
180 s autoreactivity by stimulating plasmacytoid dendritic cells-(pDCs)-Type I interferon (IFN-I) and act
188 7 macrophages and murine bone marrow-derived dendritic cells; we now show that SLP-8321 and SLP-5818
190 However, if electrical synapses were in axo-dendritic connections, where chemical synapses occur, th
192 idence for a conserved role of Tao kinase in dendritic development and function of sensory neurons, s
193 ured organization of E and I synapses across dendritic domains as well as within individual dendritic
194 unique arborization subdivided in segregated dendritic domains receiving distinct excitatory synaptic
195 e contacted by multiple BC4s through ongoing dendritic elaboration between 1 and 6 months of age-well
197 in a displacement of the normally occurring dendritic epidermal T cells (DETC) concomitant with an a
198 ss, enhanced corneocyte fragility, decreased dendritic epidermal T cells, and an exaggerated percutan
199 e that mismatches in the opposing actions on dendritic excitability may relate to these compounds' ce
201 NPY treatment reduces the complexity of the dendritic extent of anxiogenic BLA principal neurons, ma
202 achieve a constant coverage by varying their dendritic field area inversely with the local density of
204 faced with a variable number of overlapping dendritic fields to approximate a uniformity in dendriti
206 findings as to the nature of the changes in dendritic function in CA1 and PFC neurons based on the p
207 lar milieu.SIGNIFICANCE STATEMENT Changes in dendritic function, and voltage-gated ion channels in pa
210 BDNF-dependent gene expression and neuronal dendritic growth mediated by the CREB transcription fact
211 e distinct mechanisms by which they regulate dendritic growth to generate their characteristic covera
213 show that the interplay between somatic and dendritic inhibition balances the increased excitatory w
215 ic calcium dysregulation is due to a loss of dendritic inhibition via decreased NMDAR currents and re
218 iently impregnated for accurate quantitative dendritic measurements, descriptions of neuronal morphol
219 cking; however, the mechanism that regulates dendritic microtubule organization is still unclear.
226 e synthesis of DNA brick nanostructures with dendritic oligonucleotides attached to the outer surface
230 sity, and inhibition, indicative of enhanced dendritic plasticity and filtering of signals integrated
231 X (FX) suggests that increased constitutive dendritic protein synthesis yields exaggerated mGluR5-de
232 mulated neuronal growth cone development and dendritic protrusion formation, and we noted that ZBP1 a
234 e in mediating depression-like behaviors via dendritic remodeling of NAc D1-MSNs and may prove a usef
237 n experience-dependent negative regulator of dendritic segment number during the visual critical peri
238 ction selectivity independently within small dendritic segments (<10um) with remarkable accuracy.
239 of GluN2B-NMDARs between proximal and distal dendritic segments, whereas the topography of GluN2A-NMD
243 the technology to calcium imaging of entire dendritic spans of neurons as well as neural ensembles w
244 pattern (subthreshold or suprathreshold for dendritic spikes), and (3) the stimulation of neighborin
245 Taken together, our results suggest that the dendritic spine abnormalities are primary developmental
246 ck of OTR expression correlates with reduced dendritic spine densities in selected cortical regions o
248 ls with simplified dendritic arbors, reduced dendritic spine density, and diminished excitatory synap
249 greater vGlut1/PSD95 colocalization, higher dendritic spine density, and enhanced evoked AMPAR and N
250 a recruits Ror2 and Ryk receptors to enhance dendritic spine density, leading to nociceptive sensitiz
251 ved cognitive function, synaptic plasticity, dendritic spine density, microglial morphology, and brai
252 tal cortex neurons leads to perturbations in dendritic spine development and hypoconnectivity, which
254 t time, the ongoing, steady-state changes in dendritic spine dynamics in the dorsal horn associated w
255 ed the role of sleep in experience-dependent dendritic spine elimination of layer 5 pyramidal neurons
256 oenergetics, enhances synaptic viability and dendritic spine formation, and increases turnover of neu
257 n corticospinal neurons, where they regulate dendritic spine formation, axon elongation, and pontine
258 PS2APP;Trem2(ko) mice also exhibited more dendritic spine loss around plaque and more neurofilamen
259 orphology demonstrated dendritic atrophy and dendritic spine loss in dorsal striatum D1-MSNs from mic
260 In addition, Tet3 cKO mice exhibit increased dendritic spine maturation in the ventral CA1 hippocampa
261 functional synaptic plasticity and abnormal dendritic spine morphology, but little is known about ho
262 ost-synaptic currents accompanied changes in dendritic spine nano-architecture, and single-synapse cu
266 ion flow, in driving synaptic weakening and dendritic spine shrinkage during synaptic plasticity.
268 the NMDAR is required to maintain NMDARs at dendritic spine synapses and mediates the direct extrace
270 + transients were also generated on discrete dendritic spine-like structures on the melanocytes.
271 kinases are contained in axon terminals and dendritic spines adjacent to the synaptic membrane, whic
272 ion, we identified changes in pyramidal cell dendritic spines and axon initial segments consistent wi
273 that most of them were excitatory, targeting dendritic spines and displaying a macular shape, regardl
274 tau species and related signaling to protect dendritic spines and processes from Abeta-induced injury
275 knock-in mice enabled thorough evaluation of dendritic spines and synapses on pathway-identified SPNs
276 tion alone can induce tau mislocalization to dendritic spines and synaptic deficits in cultured rat h
278 We present a concise review of the role of dendritic spines in neuropathic pain and outline the pot
284 Here, we profiled the in vivo dynamics of dendritic spines over time on the same superficial dorsa
285 triatal medium spiny neurons, the density of dendritic spines, or the density or ultrastructure of co
293 rewire, two contact new cones within stable dendritic territories, whereas one expands its dendrite
294 lanocytes, melanosomes mature and traffic to dendritic tips, where they are transferred to adjacent e
295 ls had a normal complement of TRPM1 at their dendritic tips, while GPR179 accumulation was partially
296 genes establish phrenic MN organization and dendritic topography through the regulation of phrenic-s
298 targeting distal apical dendrites and apical dendritic tufts of pyramidal neurons in layer I, and rar
299 nergic modulation were mediated, in part, by dendritic voltage-gated calcium channels (VGCCs): pharma
300 ic factor (BDNF) enhances co-localization of dendritic ZBP1 and PAT1 within granules that also contai