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1 ine deoxyribonucleosides: deoxyadenosine and deoxyinosine.
2 d not only from cordycepin, but also from 3'-deoxyinosine.
3 observed except in the case of a 3'-terminal deoxyinosine.
4 ng deoxyuridine compared with DNA containing deoxyinosine.
5 godeoxyribonucleotide containing 2-fluoro-2'-deoxyinosine.
6 ses acting on RNA (ADAR enzymes) to generate deoxyinosine.
9 and pseudo-Y DNA structures, suggesting that deoxyinosine 3'-endonuclease is a bacterial functional h
10 These biochemical properties suggest that deoxyinosine 3'-endonuclease might be important in the r
14 uilding block, the O6-(benzotriazol-1-yl)-2'-deoxyinosine 5'-O-DMT 3'-O-phosphoramidite, has been pre
15 amidite monomer of N1-(2,4-dinitrophenyl)-2'-deoxyinosine 9 was prepared from 2'-deoxyinosine in four
17 ure of the N1-(1-hydroxy-3-buten-2(S)-yl)-2'-deoxyinosine adduct arising from the alkylation of adeni
19 ded a plausible hypothesis as to why this N1 deoxyinosine adduct strongly coded for the incorporation
20 '-deoxynebularine analogues) and C-2 aryl 2'-deoxyinosine analogues can be conveniently prepared via
22 e that recognizes and cleaves DNA containing deoxyinosine and base mismatches, can cleave heteroduple
23 tially high synthetic utility of 2-chloro-2'-deoxyinosine and in many instances this derivative can s
24 gPNP has kcat values of 54 and 41 s-1 for 2'-deoxyinosine and inosine, its preferred substrates, and
25 containing 2-fluoro-O(6)-trimethylsilylethyl deoxyinosines and the appropriate diamine (ethylenediami
26 in the repair of deaminated deoxyadenosine (deoxyinosine) and abasic sites in DNA, but there was no
28 Deoxyguanosine is a weaker substrate than deoxyinosine, and DADMe-Immucillin-G is less tightly bou
29 ever, levels of the DNA deamination product, deoxyinosine, and the numbers of apurinic/apyrimidinic (
32 e purified from an overproducing strain, the deoxyinosine- and mismatch-specific activities of endonu
34 es the conversion of 5'-deoxyadenosine to 5'-deoxyinosine as its major product but will also deaminat
35 ent syntheses of 2-chloro- and 2-tosyloxy-2'-deoxyinosine as their tert-butyldimethylsilyl ethers are
37 edicts that MPG should be able to remove the deoxyinosine base from the DNA strand of RNA-DNA hybrids
38 rms two stable complexes with DNA containing deoxyinosine, but not with DNA containing base mismatche
39 iation, recognition, and dissociation of the deoxyinosine by the endo V, were determined at 5.9, 14.5
40 urine 2'-deoxyribonucleoside and 2-fluoro-2'-deoxyinosine, by the amino triol then yielded diastereom
44 BcPh amino tribenzoates with the 2-bromo-2'-deoxyinosine derivative proceeded in comparable yields.
47 -dihydro-8-oxo-2'-deoxyguanosine (OxodG), 2'-deoxyinosine (dI) and 2'-deoxyguanosine (dG) in otherwis
48 and deoxycytidine (dC) were substituted with deoxyinosine (dI) and 3-(2'-deoxy-beta-D-ribofuranosyl)p
50 ing 7-deaza-2'-deoxyguanosine (dc(7)G) or 2'-deoxyinosine (dI) in place of dG support oligoribonucleo
53 nd two DNA subunits (deoxyadenosine, dA, and deoxyinosine, dI) can be coproduced in the same reaction
54 : 2'-deoxyuridine, 2'-deoxyxanthosine and 2'-deoxyinosine from nitrosative deamination; 8-oxo-2'-deox
55 l endonuclease, which cleaves the 5' side of deoxyinosine, from the hyperthermophilic archaeon, Pyroc
58 of structurally disparate lesions, including deoxyinosine (I), which results from the spontaneous oxi
60 enyl)-2'-deoxyinosine 9 was prepared from 2'-deoxyinosine in four steps and incorporated into oligome
62 e, whereupon the 5'-deoxyribose moiety of 5'-deoxyinosine is further metabolized to deoxyhexoses used
64 ugar-protected or -unprotected inosine or 2'-deoxyinosine nucleosides and 1H-benzotriazol-1-yloxy-tri
66 (dA) was substituted with adenosine (A), 2'-deoxyinosine, or 2'-deoxyuridine, toxin-dependent signal
70 oliovirus PCR primers contain mixed-base and deoxyinosine residues to compensate for the high degener
72 l shift (1.3 ppm), indicating that C-6 of 2'-deoxyinosine retains its sp2 hybridization after binding
73 e-ImmH) is a transition-state mimic for a 2'-deoxyinosine ribocation with a fully dissociated N-ribos
74 eater than 20-fold higher for DNA containing deoxyinosine than deoxynebularine or base mismatches.
76 with half-times ranging from 4 years for 2'-deoxyinosine to 40 years for 2'-deoxycytidine (37 degree
77 was performed to study the conversion of 3'-deoxyinosine to cordycepin 5'-triphosphate in vitro usin
78 ding 2'-deoxyuridine triphosphate (dUTP), 2'-deoxyinosine triphosphate (dITP), and 7-deaza-2'-deoxygu
79 omologs have high specificity for dHAPTP and deoxyinosine triphosphate compared with the four canonic
80 varation, filtering out data collected with deoxyinosine triphosphate during primer extension, gave
83 '-bis-O-(tert-butyldimethylsilyl)-2-bromo-2'-deoxyinosine, using a (+/-)-BINAP-Pd complex and Cs2CO3.
85 ts yielded a structure in which the modified deoxyinosine was in the high syn conformation about the
86 ne epoxide (BDO), followed by deamination to deoxyinosine, was determined, in the oligodeoxynucleotid
87 osine, formycin A, adenosine, inosine, or 2'-deoxyinosine were determined by x-ray crystallography wi
88 c parameters of the 'universal pairing base' deoxyinosine were determined for the pairs I.C, I.A, I.T
90 bound inosine in a different way, we labeled deoxyinosine with 13C, excepting an upfield shift of 70-
91 ...CIG*C... sequences, which contain "I" (2'-deoxyinosine), with hydrogen replacing the amino group i