ライフサイエンスコーパス: deoxyribonucleotide

1 rocarbon linkers, and a ganciclovir-modified deoxyribonucleotide.

2 ge of the glycosidic linkage in a pyrimidine deoxyribonucleotide.

3 atalyzes the reduction of ribonucleotides to deoxyribonucleotides.

4 ncing with fluorescent reversible terminator deoxyribonucleotides.

5 atalyze the conversion of ribonucleotides to deoxyribonucleotides.

6 e for RR in the formation of 8-oxodG-derived deoxyribonucleotides.

7 ing the formamidopyrimidines opposite native deoxyribonucleotides.

8 A synthesis by converting ribonucleotides to deoxyribonucleotides.

9 Fapy*dG excision opposite all four native 2'-deoxyribonucleotides.

10 als in DNA, guanine deoxyribonucleosides and deoxyribonucleotides.

11 is restrained by the limited availability of deoxyribonucleotides.

12 catalyze the reduction of ribonucleotides to deoxyribonucleotides.

13 doxin 3, thus restoring an effective pool of deoxyribonucleotides.

14 higher affinity for ribonucleotides than for deoxyribonucleotides.

15 cal for the conversion of ribonucleotides to deoxyribonucleotides.

16 meet the demand of the replication forks for deoxyribonucleotides.

17 thesis or the polymerization of the first 26 deoxyribonucleotides.

18 to both single-stranded and double-stranded deoxyribonucleotides.

19 oligonucleotides that include both ribo- and deoxyribonucleotides.

20 m bRT-catalyzed misincorporation of standard deoxyribonucleotides.

21 talyzes the conversion of ribonucleotides to deoxyribonucleotides.

22 e, thereby blocking the de novo synthesis of deoxyribonucleotides.

23 r ribonucleotides was comparable to that for deoxyribonucleotides.

24 and C2'-endo conformations are found in the deoxyribonucleotides.

25 A, it binds cooperatively to single stranded deoxyribonucleotides.

26 incorporates rNTPs almost as efficiently as deoxyribonucleotides.

27 plication stress in the presence of limiting deoxyribonucleotides.

28 atalyze the conversion of ribonucleotides to deoxyribonucleotides.

29 to discriminate between ribonucleotides and deoxyribonucleotides.

30 tial function of reducing ribonucleotides to deoxyribonucleotides.

31 ductases, which convert ribonucleotides into deoxyribonucleotides.

32 reductase, which converts ribonucleotides to deoxyribonucleotides.

33 h their strong selectivity against mispaired deoxyribonucleotides.

34 to initiate reduction of ribonucleotides to deoxyribonucleotides.

35 present at much higher levels compared with deoxyribonucleotides.

36 ucleotide reductases supply cells with their deoxyribonucleotides.

37 e reductase (RNR) catalyzes the formation of deoxyribonucleotides, a rate limiting step in DNA synthe

38 reductase (RNR) converts ribonucleotides to deoxyribonucleotides, a reaction that is essential for D

39 striking elevations in purine and pyrimidine deoxyribonucleotides, along with moderate increases in p

40 talyzes the conversion of ribonucleotides to deoxyribonucleotides, an essential step in DNA biosynthe

41 s unique in family X pols, the design of CXY deoxyribonucleotide analogues to enhance interaction is

42 dition of two molecules of the complementary deoxyribonucleotide analyte.

43 more rapidly than the corresponding correct deoxyribonucleotide and incorrect nucleotides are added

44 he conversion of all four ribonucleotides to deoxyribonucleotides and are essential for DNA synthesis

45 tion of ribonucleotides to the corresponding deoxyribonucleotides and is an essential enzyme for DNA

46 atalyzes the reduction of ribonucleotides to deoxyribonucleotides and is critical for DNA synthesis a

47 erent ribonucleotides to their corresponding deoxyribonucleotides and is the rate-limiting enzyme in

48 nto replicating DNA due to the similarity of deoxyribonucleotides and ribonucleotides, the high conce

49 ld with a heterogeneous mixture of ribo- and deoxyribonucleotides and sequences, while suggesting an

50 polymerases effectively discriminate against deoxyribonucleotides and specifically recognize ribonucl

51 ed ribonucleotides are superior to activated deoxyribonucleotides and that RNA templates are superior

52 cient enzymes that reduce ribonucleotides to deoxyribonucleotides and thus prime DNA synthesis.

53 dependent incorporation of the four natural deoxyribonucleotides and thus, significantly expand the

54 ribonucleotides despite their preference for deoxyribonucleotides, and analysis of cultured cells ind

55 ltaneous synthesis of arabinonucleotides, 2'-deoxyribonucleotides, and other variations on the canoni

56 ive site, has a role in the interaction with deoxyribonucleotides, and regulates DNA replication fide

57 atalyze the conversion of ribonucleotides to deoxyribonucleotides, and represent the only de novo pat

58 As previously shown, 2'-deoxyribonucleotides are also less efficiently incorpora

59 led region, irrespective of whether ribo- or deoxyribonucleotides are at the cleavage site.

60 Deoxyribonucleotides are DNA building blocks and are pro

61 mation, or environmental exposure, ribo- and deoxyribonucleotides are oxidatively modified.

62 tide reductase (RNR)-catalyzed production of deoxyribonucleotides are provided by glutaredoxin (Grx)

63 It is also not known where deoxyribonucleotides are synthesized in the cell.

64 Ribonucleotides and 2'-deoxyribonucleotides are the basic units for RNA and DNA

65 A comparison of the utilization of ribo- and deoxyribonucleotides as substrates indicates the existen

66 ed by Vmax/Km, c-N-I preferred pyrimidine 2'-deoxyribonucleotides as substrates with thymidine monoph

67 to template-primer in the presence of added deoxyribonucleotides, as seen by gel-shift analysis, but

68 This site discriminates against deoxyribonucleotides at the 3' end, and interactions at

69 has a DNA exonuclease activity on mismatched deoxyribonucleotides at the 3' termini of nicked or gapp

70 We adapted in two steps a deoxyribonucleotide-based aptamer to signal the recognit

71 New, emerging deoxyribonucleotide-based technologies allow integration

72 2',5'-Linked oligo-3'-deoxyribonucleotides bind selectively to complementary R

73 catalyzes the rate-limiting step in de novo deoxyribonucleotide biosynthesis and is essential in DNA

74 This key enzyme in deoxyribonucleotide biosynthesis is the target of establ

75 two enzymes required for the entire de novo deoxyribonucleotide biosynthesis, and possessed low dNTP

76 hat several metabolic pathways, particularly deoxyribonucleotide biosynthesis, branched-chain amino a

77 report that TMPK and RNR, two key enzymes in deoxyribonucleotide biosynthesis, co-localize to damaged

78 Because of the involvement of NADPH in deoxyribonucleotide biosynthesis, we asked whether mitoc

79 reonine metabolism and buffers deficiency in deoxyribonucleotide biosynthesis.

80 ribonucleotide reductase, the key enzyme for deoxyribonucleotide biosynthesis.

81 n dNTP synthetase, a multienzyme complex for deoxyribonucleotide biosynthesis.

82 ress through the inhibition of nucleotide or deoxyribonucleotide biosynthesis.

83 catalyzes the rate-limiting step in de novo deoxyribonucleotide biosynthesis.

84 iency for r8-oxo-GTP compared with canonical deoxyribonucleotides but that r8-oxo-GTP is inserted mut

85 DinB2 effectively incorporates deoxyribonucleotides, but not ribonucleotides, opposite

86 reduces ribonucleotides to the corresponding deoxyribonucleotides by a reversible radical transfer me

87 se substituents were incorporated into oligo-deoxyribonucleotides by standard phosphoramidite methodo

88 leotide reductases catalyze the formation of deoxyribonucleotides by the reduction of the correspondi

89 f the ribonucleotides to their corresponding deoxyribonucleotides catalysed by ribonucleotide reducta

90 sion of ribonucleotides to the corresponding deoxyribonucleotides catalyzed by the enzyme ribonucleot

91 Most significant deoxyribonucleotide changes were present in the gut and

92 Synthetic deoxyribonucleotide competition studies defined the RNA-

93 chimeras, i.e. tRNA3Lys extended by 5 and 31 deoxyribonucleotides complementary to the viral genome u

94 in nonreplicating cells containing very low deoxyribonucleotide concentrations.

95 suggest that NrdR activity is modulated by a deoxyribonucleotide corepressor.

96 Three sets of semi-self-complementary deoxyribonucleotide decamers with the sequence XX-(5meCG

97 The misincorporation of 2'-deoxyribonucleotides (dNs) into RNA has important implic

98 CLEOSIDE HYDROLASE 1, demonstrating that the deoxyribonucleotide (dNT) metabolism is intricately inte

99 in macrophages by reducing the intracellular deoxyribonucleotide (dNTP) pool to levels below those re

100 it responsible for normal maintenance of the deoxyribonucleotide (dNTP) pool used for DNA replication

101 affected by the balance and concentration of deoxyribonucleotide (dNTP) pools, which are strictly reg

102 plication stress are alterations in pools of deoxyribonucleotide (dNTP) precursors required for DNA s

103 esulting in nucleotide synthesis disruption, deoxyribonucleotide (dNTP) starvation, and cell-cycle ar

104 cal studies have shown that CTPS can bind to deoxyribonucleotides (dNTPs) to produce 2'-deoxycytidine

105 Cross-linking analogs and radioactive deoxyribonucleotides (dNTPs), followed by normal dNTPs,

106 DNA) replication requires a steady supply of deoxyribonucleotides (dNTPs), synthesized de novo by rib

107 talyzes the conversion of ribonucleotides to deoxyribonucleotides (dNTPs), which are necessary for bo

108 ation of DNA requires a sufficient supply of deoxyribonucleotides (dNTPs), which are produced by ribo

109 When a synthesized deoxyribonucleotide duplex, 5'-CCATCGCTACC-3'.5'-GGTAGCG

110 le to incorporate ribonucleotides as well as deoxyribonucleotides during polymerization and is resist

111 vides the only de novo means of synthesizing deoxyribonucleotides, essential precursors for DNA repli

112 pucker and conformational flexibility of the deoxyribonucleotide exhibited cleavage rates comparable

113 In mammals thymidine kinase supplies deoxyribonucleotides for DNA replication and DNA repair,

114 reductase (RnR) is a key enzyme synthesizing deoxyribonucleotides for DNA replication and repair.

115 eductase activity is required for generating deoxyribonucleotides for DNA replication.

116 ich catalyzes the rate-limiting synthesis of deoxyribonucleotides for DNA replication.

117 Production of deoxyribonucleotides for DNA synthesis is an essential a

118 s I ribonucleotide reductases (RRs) generate deoxyribonucleotides for DNA synthesis.

119 diphosphates, ensuring a balanced supply of deoxyribonucleotides for DNA synthesis.

120 ase to convert imported ribonucleotides into deoxyribonucleotides for DNA synthesis.

121 apable of utilising both ribonucleotides and deoxyribonucleotides for primer synthesis in the presenc

122 atalyzes the reduction of ribonucleotides to deoxyribonucleotides for use in DNA synthesis.

123 oxo-G) is a common oxidized nucleobase whose deoxyribonucleotide form, 8-oxo-dGTP, has been widely st

124 e the rate-limiting step in the synthesis of deoxyribonucleotides from the corresponding ribonucleoti

125 cycle of the ribonucleotide opposing the TFI deoxyribonucleotide had no effect on the human RNase H1

126 Our results uncover that the deoxyribonucleotide immediately upstream of the rNMPs ha

127 base pair formed between a template adenine deoxyribonucleotide in the syn conformation and a deoxyt

128 atalyze the conversion of ribonucleotides to deoxyribonucleotides in all organisms.

129 o induce DNA damage and hydroxyurea to limit deoxyribonucleotides in cells deprived of DBF4 function

130 n of (2)H(2)O into the deoxyribose moiety of deoxyribonucleotides in dividing cells.

131 O into the deoxyribose (dR) moiety of purine deoxyribonucleotides in dividing cells.

132 H(2)O) into the deoxyribose moiety of purine deoxyribonucleotides in DNA of dividing cells, by use of

133 H(2)O) into the deoxyribose moiety of purine deoxyribonucleotides in DNA of dividing cells.

134 the properties of arabinonucleotides and 2'-deoxyribonucleotides in nonenzymatic template-directed p

135 r data identify a previously unknown role of deoxyribonucleotides in regulation of OIS.

136 phosphate disclose the novel binding mode of deoxyribonucleotides in the active site.

137 folding with the incorporation of 2'-methoxy deoxyribonucleotides in the capture sequences.

138 We demonstrate that deoxyribonucleotides in the guide strand overhang of siR

139 sonably close to the proportions of the four deoxyribonucleotides in the vaccinia virus genome, but o

140 ain, synthetic U6 RNAs were constructed with deoxyribonucleotides incorporated site specifically.

141 omopolymeric templates indicate that initial deoxyribonucleotide incorporation is complementary to th

142 ignificantly higher velocity and fidelity of deoxyribonucleotide incorporation on RNA versus DNA.

143 r substituted 1,2,3-triazolyl phosphonate-2'-deoxyribonucleotide internucleotide linkage.

144 Multiple substitutions of deoxyribonucleotides into RNA stem-loops in one case (dG

145 -hydrogen bonding base modifications, abasic deoxyribonucleotides, intranucleotide hydrocarbon linker

146 DNA when the access to cytosolic pyrimidine deoxyribonucleotides is limited.

147 oxidized adenine [A(-H)*] in dAdo and its 2'-deoxyribonucleotides leads to formation of deoxyribose s

148 The control of deoxyribonucleotide levels is essential for DNA synthesi

149 tidic) thymidine kinase has severely altered deoxyribonucleotide levels, less chloroplast DNA, and ch

150 cleotide reductase and reduces intracellular deoxyribonucleotide levels, these results suggest that N

151 ality that is rescued by increasing cellular deoxyribonucleotide levels.

152 v1 discriminates between ribonucleotides and deoxyribonucleotides mainly by reducing the rate of inco

153 Furthermore, activated 2'-deoxyribonucleotides maintain a C2'-endo sugar pucker in

154 The absence of the 2'-hydroxyl group of the deoxyribonucleotide may destabilize binding of the ligan

155 At the same time, aspects of deoxyribonucleotide metabolism have been shown to be cri

156 es a rate-limiting step in the production of deoxyribonucleotides needed for DNA replication and repa

157 ze the only pathway for de novo synthesis of deoxyribonucleotides needed for DNA replication and repa

158 raceable quantification of ribonucleotide or deoxyribonucleotide oligomers is achievable using acid h

159 i fragment consisted of five ribo- and seven deoxyribonucleotides on the hybrid strand, together with

160 Y122*), which is essential for production of deoxyribonucleotides on the larger R1 subunit.

161 f ribonucleotides (rATP or rCTP), instead of deoxyribonucleotides, opposite 8-oxo-2'-deoxyguanosine (

162 l preference for the incorporation of either deoxyribonucleotides or ribonucleotides during chain elo

163 ses exhibit a high degree of selectivity for deoxyribonucleotides over ribo- or dideoxynucleotides.

164 yeast have surprisingly low selectivity for deoxyribonucleotides over their analogous ribonucleotide

165 Class II AP endonuclease, deoxyribonucleotide phosphate (dRP) lyase, DNA synthesis

166 using 5'-O-(2-methoxyprop-2-yl)-protected 2'-deoxyribonucleotide phosphoroamidite building blocks wit

167 t cells display both a mutator phenotype and deoxyribonucleotide pool abnormalities.

168 ase genes, and measurements of intracellular deoxyribonucleotide pool concentrations.

169 Ribonucleotide reductase maintains cellular deoxyribonucleotide pools and is thus tightly regulated

170 ragilis NrdAB may have a role in maintaining deoxyribonucleotide pools for DNA repair and growth reco

171 on and repair requires adequate and balanced deoxyribonucleotide pools that are maintained primarily

172 R function to avoid inadequate or unbalanced deoxyribonucleotide pools that cause DNA damage and geno

173 on of RNR genes and to decrease the cellular deoxyribonucleotide pools.

174 efore, 5-azaC causes a major perturbation of deoxyribonucleotide pools.

175 as precursors for DNA repair and to balance deoxyribonucleotides pools.

176 ying DNA synthesis with isotopically labeled deoxyribonucleotide precursors.

177 , which catalyzes the rate-limiting step for deoxyribonucleotide production required for DNA synthesi

178 on of ribonucleotides to their corresponding deoxyribonucleotides, providing a balanced supply of pre

179 ucleotides are found in great abundance over deoxyribonucleotides, raising the possibility that ribon

180 a 25-nt homology domain comprised of a five-deoxyribonucleotide region (harboring a single base mism

181 2 subunits, RRM1 and RRM2, that provides the deoxyribonucleotides required for DNA synthesis/repair.

182 tion of a 2'-deoxyribo- or 2',2'-difluoro-2'-deoxyribonucleotide resulted in strong chain termination

183 e, 2'-methoxyethyl nucleotide, or mismatched deoxyribonucleotide resulted in the ablation of the 5'-m

184 Polo on a DNA/RNA primer-template with bound deoxyribonucleotide reveals that the enzyme undergoes a

185 port a method to hydrolyze RNA to release 2'-deoxyribonucleotide-ribonucleotide pairs (dNrN) that are

186 rential screening as a new PET probe for the deoxyribonucleotide salvage pathway.

187 the RNase H activation property of the 3'-5'-deoxyribonucleotide segment adjacent to the modification

188 ides (MBOs) containing 2'-5'-ribo- and 3'-5'-deoxyribonucleotide segments.

189 ster bond on the 5' side of a ribonucleotide-deoxyribonucleotide sequence in substrates mimicking RNA

190 al data indicate that primase incorporates a deoxyribonucleotide stochastically during elongation and

191 erved for Okazaki-like substrates containing deoxyribonucleotide substitutions at the 3' pole of the

192 the loss of discrimination between ribo- and deoxyribonucleotide substrates as well as to defects in

193 nucleotidyl-transfer reaction to incorporate deoxyribonucleotides successively; however, our knowledg

194 against incorporation of ribonucleotides, 3'-deoxyribonucleotides (such as cordycepin) and 2',3'-dide

195 n to mimic the carbohydrate components of 2'-deoxyribonucleotides suggest that 2'-deoxy-5-methyleneur

196 crease in the concentration of intracellular deoxyribonucleotides, suggesting that one effect of the

197 und in many biochemical processes, including deoxyribonucleotide synthesis and oxidative DNA damage.

198 iae, many genes encoding enzymes involved in deoxyribonucleotide synthesis are expressed preferential

199 ngation of the replication fork by impairing deoxyribonucleotide synthesis by inhibiting the activity

200 d higher concentrations of the inhibitors of deoxyribonucleotide synthesis FUdR, methotrexate and hyd

201 sential iron-dependent enzyme that catalyzes deoxyribonucleotide synthesis in eukaryotes.

202 Similarly, reduced deoxyribonucleotide synthesis increases the ribonucleoti

203 ) reductase and further supply electrons for deoxyribonucleotide synthesis, antioxidant defense, and

204 ide reductase subunit M2 (RRM2), involved in deoxyribonucleotide synthesis, drives the chemoresistanc

205 Inactivating ATP production, deoxyribonucleotide synthesis, or ribosome production bl

206 lic processes, including electron transport, deoxyribonucleotide synthesis, oxygen transport and many

207 ctions in many cellular processes, including deoxyribonucleotide synthesis, repair of oxidatively dam

208 coordinating DNA replication with increased deoxyribonucleotide synthesis.

209 etween the initiation of DNA replication and deoxyribonucleotide synthesis.

210 ls by controlling the rate-limiting step for deoxyribonucleotide synthesis.

211 either DNA damaging agents or inhibitors of deoxyribonucleotide synthesis.

212 A-binding protein in organizing a complex of deoxyribonucleotide-synthesizing enzymes at the replicat

213 These experiments showed several deoxyribonucleotide-synthesizing enzymes to be present i

214 Thus, the induction of deoxyribonucleotide-synthesizing genes at G1/S was fully

215 The relationship between the induction of deoxyribonucleotide-synthesizing genes, deoxyribonucleos

216 hosphate accumulation, like the induction of deoxyribonucleotide-synthesizing genes, was not dependen

217 required for normal cell cycle regulation of deoxyribonucleotide-synthesizing genes.

218 003W94, a 15-base phosphorothioate antisense deoxyribonucleotide that is currently under preclinical

219 yuridylate, which results in an imbalance of deoxyribonucleotide that may lead to excessive uracil mi

220 tion of ribonucleotides to the corresponding deoxyribonucleotides, the building blocks of DNA.

221 catalyze the reduction of ribonucleotides to deoxyribonucleotides, thereby playing a key role in DNA

222 beling the deoxyribose (dR) moiety of purine deoxyribonucleotides through the de novo nucleotide synt

223 t involves the covalent linkage of the first deoxyribonucleotide to the polymerase polypeptide.

224 The LigD2 POL domain adds ribonucleotides or deoxyribonucleotides to a DNA primer-template, with rNTP

225 se module (POL) that adds ribonucleotides or deoxyribonucleotides to DSB ends and primer-templates.

226 retaining its normal ability to incorporate deoxyribonucleotides to form DNA.

227 talyzes the conversion of ribonucleotides to deoxyribonucleotides to provide the monomeric building b

228 oltheta shows a strong preference for adding deoxyribonucleotides to RNA, but can also add ribonucleo

229 rate that Poltheta efficiently adds 30-50 2'-deoxyribonucleotides to the 3' terminus of RNA molecules

230 further confirmed by DNA ladder and terminal deoxyribonucleotide transferase-mediated dUTP nick end l

231 Terminal deoxyribonucleotide transferase-mediated dUTP nick-end l

232 ll nuclear antigen), and apoptosis (terminal deoxyribonucleotide transferase-mediated nick-end labeli

233 cell nuclear antigen) / apoptosis (terminal deoxyribonucleotide transferase-mediated nick-end labeli

234 LC25A19, also called DNC, is a mitochondrial deoxyribonucleotide transporter.

235 er catalytic efficiency for rNTP relative to deoxyribonucleotide triphosphate (dNTP) incorporation, r

236 Perturbation of the deoxyribonucleotide triphosphate (dNTP) pool is recogniz

237 in the incorporation efficiency of a correct deoxyribonucleotide triphosphate (dNTP) relative to wild

238 hrough enhancement of LVDr changes in the RT deoxyribonucleotide triphosphate (dNTP)-binding pocket.

239 coordinately regulated to ensure appropriate deoxyribonucleotide triphosphate levels.

240 Thus, the coordinate repression of deoxyribonucleotide triphosphate metabolic enzymes is de

241 wever, we find that DinB incorporates the tC deoxyribonucleotide triphosphate opposite template G and

242 a limited, "fine-tuning" role in regulating deoxyribonucleotide triphosphate pools produced by the d

243 s high ratios of ribonucleotide triphosphate:deoxyribonucleotide triphosphate pools result in approxi

244 ave severe TYMS deficiency, altered cellular deoxyribonucleotide triphosphate pools, and hypersensiti

245 hen forks stall because of DNA damage or low deoxyribonucleotide triphosphate pools.

246 rdgB gene encodes a protein homologous to a deoxyribonucleotide triphosphate pyrophosphatase from Me

247 a molybdoenzyme, thought to detoxify HAP, a deoxyribonucleotide triphosphate pyrophosphatase that re

248 SAMHD1 forms tetramers that possess deoxyribonucleotide triphosphate triphosphohydrolase (dN

249 ination of free energy released during dNTP (deoxyribonucleotide triphosphate) hydrolysis and thermal

250 aining TFOs using its commercially available deoxyribonucleotide triphosphate.

251 ribonucleotide triphosphates (NTPs) but not deoxyribonucleotide triphosphates (dNTPs) and instead us

252 e rate-limiting step of de novo synthesis of deoxyribonucleotide triphosphates (dNTPs) building block

253 lyzes an essential step in the production of deoxyribonucleotide triphosphates (dNTPs) in cells.

254 e reductase (RNR) and increased synthesis of deoxyribonucleotide triphosphates (dNTPs) required for D

255 only enzyme capable of de novo synthesis of deoxyribonucleotide triphosphates (dNTPs).

256 Viral DNA replication requires deoxyribonucleotide triphosphates (dNTPs).

257 te pyrophosphatase that removes noncanonical deoxyribonucleotide triphosphates from replication precu

258 not discriminate between ribonucleotide and deoxyribonucleotide triphosphates, and it unwinds duplex

259 A trend in signal intensity for deoxyribonucleotide triphosphates, oligonucleotides, and

260 triphosphates (rNTPs) is higher than that of deoxyribonucleotide triphosphates.

261 n which diaminopurine (DAP) replaced adenine deoxyribonucleotide triphosphates.

262 orporation of both ribonucleotide- (NTP) and deoxyribonucleotide-triphosphates (dNTPs) using spCSR.

263 The deoxyribonucleotide triphosphohydrolase SAMHD1 restricts

264 tion of ribonucleotides to the corresponding deoxyribonucleotides, used in DNA synthesis and repair.

265 reductases (RNRs) reduce ribonucleotides to deoxyribonucleotides using radical-based chemistry.

266 reductases (RNRs) convert ribonucleotides to deoxyribonucleotides via radical-based chemistry.

267 he apparent affinity of Glu-297 3Dpol for 2'-deoxyribonucleotides was decreased by 6-fold relative to

268 t molecular beacons synthesized from natural deoxyribonucleotides were not suitable, because they are

269 roposed to act as the selectivity switch for deoxyribonucleotide, which is supported by comparison to

270 tion of ribonucleotides to the corresponding deoxyribonucleotides, which are used as building blocks

271 Ribonucleotides are the natural analogs of deoxyribonucleotides, which can be misinserted by DNA po

272 , preventing elimination of oxidized guanine deoxyribonucleotides, which was achieved by suppressing

273 ess than 1/150000, and incorporation of a 2'-deoxyribonucleotide with a correct base should occur at

274 reported that DNA base pairs formed between deoxyribonucleotides with large aromatic, predominantly

275 A series of oligo-2'-deoxyribonucleotides with parallel (ps) and antiparallel