ライフサイエンスコーパス: dependency

1 two independent cohorts, showing partial RNA dependency.

2 le recurrent inhibition also shows phenotype dependency.

3 d with poultry, supported by n-3 LCPUFA dose dependency.

4 ns were seen with impairment, disability and dependency.

5 er delineation of the biology underlying Ras dependency.

6 anding of responses and to interpret context dependency.

7 as an acute myeloid leukemia (AML)-selective dependency.

8 carbon metabolism in CaP creates a metabolic dependency.

9 ions of maximal (i.e., the most long-ranged) dependency.

10 mic structure with distinct localization and dependency.

11 f containers for packaging software and data dependencies.

12 imposed by trophic, service, and engineering dependencies.

13 spacings, quantum numbers, as well as field dependencies.

14 order results from a loss of regulatory gene-dependencies.

15 between units are defined by pairwise spike dependencies.

16 o well-recognised temporal and spatial scale dependencies.

17 d to different stimuli in order to establish dependencies.

18 ke signals, although with different temporal dependencies.

19 provides a strategy for defining their core dependencies.

20 sfunctional gene splicing and tumor-specific dependencies.

21 on cannot comprehensively capture BOLD inter-dependencies.

22 late biosynthetic pathways as MESN-selective dependencies.

23 from modified gene dosage defines background dependencies.

24 erences in Gag sequence but similar cofactor dependencies.

25 ms for discovering and characterizing cancer dependencies.

26 rhabdomyosarcoma and identify critical CR TF dependencies.

27 n involves 2 steps with opposite temperature dependencies.

28 ich are known to increase aspartate and GOT1 dependencies.

29 putational principles underlie these history dependencies.

30 e biases, gene expression profiles, and gene dependencies.

31 rse interactions connect species in a web of dependencies.

32 obtained model parameters and their pressure dependencies, a thermodynamic description was made and c

33 alone, are predictive of long-term pacemaker dependency after TAVR, thus influencing device selection

34 n anatomic factors predisposing to pacemaker dependency after TAVR.

35 ate and the possible predictors of pacemaker dependency after TAVR.

36 Yet, social dependency also comes at a cost.

37 n's correlation captures linear, time-domain dependencies among blood-oxygen-level-dependent (BOLD) s

38 For systems that involve complex causal dependencies among many variables, the complexity of the

39 uantitative framework to extract significant dependencies among scientific disciplines and turn them

40 s nutrients and the potential for unexpected dependencies among systems that mediate colonization and

41 cellular variables, which allow us to infer dependencies among those variables from their apparent c

42 Moreover, there is a complex non-linear dependency among heterogeneous data.

43 t representations and then models non-linear dependency among several domains.

44 To better understand host-virus genetic dependencies and find potential therapeutic targets for

45 nic change in biodiversity; however, context dependencies and interactions with co-occurring stressor

46 ial effort reading documentation, installing dependencies and moving between analysis and visualisati

47 ssues to be analyzed independently, ignoring dependencies and similarities between tissues, or to mer

48 This ignores the data dependencies and that pathways are incomplete or conditi

49 hnologies to understand synthetically lethal dependencies and track cancer evolution through therapy

50 ability to correctly uncover cancer genetic dependencies and will facilitate the development of impr

51 Such technology-dependency and assembly-size dependency require research

52 mal one, stability under continuous flow, pH dependency and bias stress effects on electrode instabil

53 Environmental dependency and genetic redundancy can explain the mainte

54 Wnt dependency and Lgr5 expression define multiple mammalian

55 n of menin (MEN1) and MLL (MLL1, KMT2A) is a dependency and provides a potential opportunity for trea

56 tumor 3D clusters recapitulated mutant KRAS dependency and recalcitrance to MEK inhibition.

57 urvival in certain cancers, suggesting tumor dependency and therefore a potential therapeutic target.

58 static fitness, refined transcription factor dependencies, and a distinct molecular phenotype.

59 iated, strategies targeting cancer metabolic dependency appear to be promising in the development of

60 survival, but the mechanisms underlying this dependency are not understood.

61 6 and the mechanisms that may undermine such dependency are poorly understood.

62 we detect efficiency and spectral nonlinear dependencies, as well as signatures of spatial delocaliz

63 Pacemaker dependency at 30 days and 1 year and all-cause mortality

64 ntage of combining an ontology and a symptom-dependency-aware naive Bayes classifier.

65 agy pathways can improve the capture of KRAS dependency better than targeting RAF alone.

66 ADMs can model dependencies between adjacent nucleotides, unlike PPMs.

67 etwork disconnections and strong 'parasitic' dependencies between collaterally damaged ischaemic area

68 The correlation predicts nonlinear dependencies between power density, substrate concentrat

69 orrelation analysis designed to model mutual dependencies between symptom dimensions and neural measu

70 architecture of the CNN captures contextual dependencies between the spectral features.

71 al investigation, to reveal correlations and dependencies between the studied parameters.

72 ses using copulas that can capture nonlinear dependencies between two sets of data.

73 zed rate constant (k(SA)) showed a strong pH dependency between 5.5 and 7.0 and followed a linear fre

74 tially private MAF queries and utilizing the dependency between tuples, an adversary can reveal up to

75 is measured using bounded scales, there is a dependency between variability and mean levels: at low (

76 ative emotional variability was clouded by a dependency between variability and the mean.

77 For HPS dependency, bowel anatomy was significantly associated w

78 We provide analyses of these dependencies by establishing a stochastic model.

79 of ILC2s and suggest that modulation of fuel dependency by autophagy is a potentially new therapeutic

80 pS-STAT3 dependency by Helicobacter coincided with transcriptiona

81 We propose that such context dependencies can be clarified by rescaling climate gradi

82 These dependencies can be related to the degree of a node and

83 cleaner-client interaction patterns: context-dependency can hence regulate mutualisms both directly a

84 However, the extent to which such history dependency can steer communities towards functionally di

85 xponentially distributed with some flow rate dependencies caused by erosion and restructuring by the

86 We termed such genes "collateral dependencies" (CDs) and identified two classes of combin

87 nic strength, the cationic Hofmeister series dependency, charge inversion and a continuously decreasi

88 However, these complex context dependencies could be substantially reduced or eliminate

89 Strikingly, analysis of genome-wide cancer dependency databases identifies CHD4 as a general cancer

90 xcitability demonstrated long-range temporal dependencies decaying according to a power law across tr

91 Activity-of-daily-living dependencies decreased from an average of 6 (95% CI, 5.9

92 nt understanding of the phenotype, function, dependencies, derivation, and modulations of VAT Tregs,

93 ol their proliferation and divergent lineage dependencies during tumor progression.

94 formation, cells with reduced growth factor dependency, enhanced neurosphere formation in vitro, and

95 ctional readout and constructed a viral host-dependency epistasis map (vE-MAP) of 356 human genes lin

96 The identification of host dependency factors and defence strategies as presented i

97 hIP further links PEL super-enhancers to PEL dependency factors MYC, IRF4, MCL1, CCND2, MDM2, and CFL

98 Host dependency factors that are required for influenza A vir

99 udies reveal region-specific transcriptional dependencies for astrocytes and identify astrocytic NFIA

100 e with patient survival and define molecular dependencies for targeted treatment approaches.

101 The cell-context dependency for RNA binding proteins (RBPs) mediated cont

102 JS-MS 2.0, a software suite that provides a dependency-free, browser-based, one click, cross-platfor

103 This context-dependency further complicates our understanding of muta

104 Cancer 'genetic dependencies' - genes whose products are essential for c

105 plexity arising from the evidence of context-dependencies has underscored a difficulty in establishin

106 These dependencies have already been observed earlier with die

107 ependent, but no physiologic details of this dependency have been established.

108 (HR, 1.49 [CI, 1.04 to 2.13]), or functional dependencies (HR, 1.09 [CI, 1.00 to 1.20]).

109 To identify molecular dependencies in Burkitt lymphoma, we performed RNAi-base

110 ify and interpret those important long-range dependencies in influencing chromatin profiles.

111 Here, to specifically identify novel dependencies in LSCs, we screened a bespoke library of s

112 As this reflects temporal dependencies in natural settings, our findings reveal a

113 iated tumorigenesis and subsequent oncogenic dependencies in prostate cancer.

114 targets as phospho-sensors to reveal kinase dependencies in tumour biopsies and cell lines.

115 We studied PQ heart rate dependency in 599 healthy subjects (aged 33.5 +/- 9.3 ye

116 networks (GCN) can capture such neighborhood dependency in a graph.

117 B6 pathway as a pharmacologically actionable dependency in AML.

118 d RDIs faithfully represent a measure of Ras dependency in both cancer cell lines and patient samples

119 on of somatotopic organization and intensity dependency in driving distinct autonomic pathways could

120 r and genetic context nominates a DNA repair dependency in KRAS-mutant cells, mediated by a network c

121 We define a pyruvate dehydrogenase (PDH) dependency in leader cells that can be therapeutically e

122 This provides a basis for MSI2 increased dependency in leukemia cells compared to normal cells.

123 ion in vivo and reveals a mevalonate pathway dependency in p53 mutant PDAC cells that have undergone

124 his flux while simultaneously targeting this dependency in prostate cancer results in an effective th

125 ubstantial functional dissociations and task dependency in the contribution of prefrontal cortical re

126 The dependency in the data due to repeated measures was acco

127 edator populations, and suggest that context dependency in top-down, bottom-up and density-dependent

128 article, the charging induces a strong depth dependency in transition metal valence.

129 study of the intrinsic character and strain dependency in transition-metal nitrides remains challeng

130 , independent predictors of 30-day pacemaker dependency included left ventricular outflow tract calci

131 These dependencies increase the urgency to understand the regu

132 the determination and reproducibility of Ras-dependency indexes (RDIs) have limited their application

133 Host microRNA (miRNA) dependency is a hallmark of the human pathogen hepatitis

134 The depth dependency is consistent with a model in which mixing in

135 Increased OXPHOS dependency is frequently a hallmark of cancer stem cells

136 This shift of fuel dependency led to impaired homeostasis and T(H)2 cytokin

137 aseline cognition, low education, pre-morbid dependency, leucoaraiosis, and diabetes (p<0.0001 for al

138 several metabolic parameters displayed donor dependency, LHM may also be used in studies for personal

139 This structural dependency makes CCS a promising characteristic for comp

140 ale loss-of-function screens from the cancer dependency map project.

141 ntial survival gene datasets from The Cancer Dependency Map, the latter of which catalogs genes drivi

142 in cancer cell lines generated by the Cancer Dependency Map, we observe that half of all constitutive

143 dilution effect further indicated that scale-dependency may strengthen the dilution effect only when

144 thoroughly characterize these networks, time dependencies must be explicitly modeled.

145 pth alone were not associated with pacemaker dependency (odds ratio, 0.79 [95% CI, 0.60-1.05]; P=0.11

146 e findings explain the distinct DNA sequence-dependencies of metazoan and S. cerevisiae initiators in

147 me-wide CRISPR analysis to map the molecular dependencies of pancreatic cancer stem cells, highly the

148 h may be useful for identifying host factors dependencies of phages, which would provide valuable inf

149 odel in which tightly-intertwined biological dependencies of RNA and protein reflect a long co-evolut

150 of acentriolar cells was performed to reveal dependencies of satellite composition on intact centroso

151 data trends establish that the chain length dependencies of the dielectric constant and surface hydr

152 The dependencies of the enhanced thermomechanical properties

153 lidated the respective monomer concentration dependencies of the nucleation and elongation processes.

154 tigate the behaviors of cancer cells and the dependencies of treatment responses, thereby enabling a

155 ulations describe the axial and spring-index dependencies of twist-enhanced cooling and its origin in

156 To characterize host dependencies of two novel Escherichia coli phages, the T

157 A genome-wide screen uncovered a general dependency of aneuploid cells on a pathway of ubiquitin-

158 d B cells similarly demonstrated the greater dependency of B cells on mitochondrial function.

159 We observe a clear dependency of cross-linking rates on the electrophilicit

160 asing projections for electric vehicles, the dependency of current Li-ion batteries on the ever-fluct

161 ays old transgenic worms, indicating the age dependency of disease outbreak, and sharing intriguing p

162 (2) warm climates of the past, and the state dependency of ECS may play an increasingly important rol

163 a computational myofibre model we study the dependency of electrical propagation and force developme

164 community changes, demonstrating the context-dependency of extreme storm responses in a subtropical c

165 put to the algorithms to address multidriver dependency of FCH(4) and reduce the internal complexity

166 h a wide range of habitats, so assessing the dependency of fisheries on coral reefs is important for

167 In contrast to the climate dependency of greening, we find spatially uniform increa

168 By understanding the dependency of HCMV on the mitochondria, we could exploit

169 nates with this effect because of the strong dependency of iron oxyhydroxide solubility on pH.

170 We conduct follow-up studies to verify the dependency of JEV on these genes, and identify functiona

171 The dependency of lymphomas on MNT for survival suggests tha

172 An accurate understanding of the structural dependency of microRNAs for their biological functions i

173 Given the exceptional dependency of MPNST cells on HuR for survival, prolifera

174 lgorithm thus can take into account both the dependency of neighboring pairing positions and the glob

175 (cystine) via system x(C) (-) is a critical dependency of pancreatic ductal adenocarcinoma (PDAC), w

176 te cancer (PCa) biology, as evidenced by the dependency of PCa cells on the androgen receptor (AR), a

177 any a priori assumptions about the spectral dependency of photobleaching.

178 Initially demonstrating a dependency of preloaded lipids on an invasive phenotype,

179 lso provide new insights into the metabolism dependency of proinflammatory and anti-inflammatory ILC2

180 e polymerizing system stands out in that the dependency of Q on protomer concentration switches from

181 onal status, staffing level, or the level of dependency of residents within the nursing home.

182 Our findings highlight the context dependency of resource exchange between plants and AM fu

183 We demonstrate location dependency of RS domain activity on regulation of TRA2be

184 We present a comprehensive overview of the dependency of several Old World alphaviruses for the hos

185 quantifiable expectations about the context-dependency of species interactions.

186 Our findings also reveal the context dependency of such relationships and the importance of t

187 imulations were performed to assess the time dependency of SUVR-1.

188 rm (90)Sr trend in stream water and the time-dependency of the (90)Sr-Q relationship.

189 se a hydrochemical model to explain the time-dependency of the (90)Sr-Q relationship.

190 del system to explain the pronounced solvent dependency of the carbenoid stability.

191 good agreement for the predicted functional dependency of the competition as a function of position,

192 vide a framework for reconciling the context dependency of the dominance of electrostatic interaction

193 izing prepulses allowed us to highlight time dependency of the I(K1) formulations.

194 resent effort clearly illustrate a quadratic dependency of the ion-neutral particle collision cross s

195 They include the strong cyclophilin dependency of the life cycle of many coronaviruses, incl

196 Here, we report a charge-state dependency of the magnetic proximity effects between MoS

197 ion probabilities we extract reveal a strong dependency of the molecule-surface interaction on the ro

198 Here, we dissected the mechanism of miRNA dependency of the pestivirus bovine viral diarrhea virus

199 imation on longitudinal data due to the time-dependency of the process.

200 e agricultural sustainability, but the scale dependency of the processes that shape diversity and of

201 vision, social function, role limitation and dependency of the socioeconomic subscale.

202 between the dynamic regimes and the general dependency of the spiral period on the heterogeneity and

203 However, the size dependency of their structural properties that impacts t

204 yields (AQYs) that capture the dual spectral dependency of this process and are applicable to polychr

205 We found a strong dependency of TRF2-null ES cells on the telomere-associa

206 study uncovers a previously underappreciated dependency of tumor cells on HR signaling for anchorage-

207 (2020) uncover the basis for a dependency of tumor cells with deregulated MYC on the ki

208 derivative to rationally target the proline-dependency of tumour growth.

209 lex with di-Ub chains reveal a concentration-dependency of UBAN/di-Ub binding stoichiometry.

210 This study sought to evaluate the time dependency of valve culture results (positive valve cult

211 Age and sex dependency of variables was analyzed and the association

212 een centers in estimates of survival and HPS dependency often reflect differences in population chara

213 ion, it also creates vulnerabilities such as dependencies on 'superfluous' repair mechanisms and the

214 constant, and surface hydrophobicity exhibit dependencies on both the length (n) and parity (n(odd) o

215 Dependencies on GBAF in malignancies without SWI/SNF abe

216 ealing environmental or spatial differential dependencies on NRF2 and reveal exploitable vulnerabilit

217 O(i) and R(n) indicated relatively high dependencies on temperature, respectively.

218 -specific roles for autophagy and functional dependencies on the p53 and NRF2 stress response mechani

219 ies for melanoma cells due to their acquired dependencies on these programs for survival, which can b

220 how insertions and deletions differ in their dependencies on these repair pathways.

221 climate change, energy demand, land use, and dependency on animal-source feed inputs per kg of fillet

222 1-mutant lung cancers and suggest that their dependency on ATR can be leveraged therapeutically and p

223 flexibility of the parasite, addressing the dependency on biosynthesis or salvage of fatty acids (FA

224 For compounds which showed dependency on both time and temperature, the p-value for

225 igration reactivation rates appeared to show dependency on both time from migration and age.

226 oup biosynthesis and its potential metabolic dependency on chorismate in P. falciparum.

227 Induction of and cellular dependency on de novo sphingolipid synthesis via PAQR4 h

228 effects of peptoid architecture and sequence dependency on DNA origami stability.

229 work for a company with a primary financial dependency on drug sales cannot serve as voting members,

230 sm(s) other than acquiring ER mutations lose dependency on ER and PR.

231 Kinome-knockdown confirmed dependency on ERBB-signalling and G2/M-checkpoint protei

232 trend, and we propose that increasing mutual dependency on external factors (also known as Moran's ef

233 state at single-molecule precision, with no dependency on external power sources while using minimal

234 ersity and flexibility, and by introducing a dependency on fortification and supplementation.

235 3xRCP6.0) and a future with continued global dependency on fossil fuels (SSP5xRCP8.5).

236 Recent studies have identified a unique dependency on GBAF (ncBAF) complexes in synovial sarcoma

237 s-specific functional roles, including major dependency on glycosaminoglycan biosynthesis, sterol reg

238 chieved by implementation of the temperature dependency on Hansen solubility parameters.

239 Inactivation curves dependency on heating technology suggests specific effec

240 A comparable dependency on heparan sulfate was also observed for La C

241 s has been less straightforward, given their dependency on light for their life cycle.

242 n day 21, was defined as death or persistent dependency on mechanical ventilation or high-flow oxygen

243 efective for CPSF6 recruitment) have reduced dependency on nuclear transport associated cofactors, al

244 el, and denoising settings; however, shows a dependency on patient size, base material, and iodine co

245 enomic regions and synovial sarcoma-specific dependency on PRC1 function.

246 delivery outcome in mice with regard to its dependency on several critical experimental factors, inc

247 estingly, ILC2(10)s demonstrated a metabolic dependency on the glycolytic pathway for IL-10 productio

248 lipoprotein to high-density lipoprotein, and dependency on the human donor.

249 rocyte-specific nature of Snorc and revealed dependency on the intronic enhancer binding of SOX9 for

250 l subtype has been associated with a loss of dependency on the original oncogenic driver, leading to

251 Modern biological dependency on trace elements is proposed to be a consequ

252 e and epigenome interrogation that decreases dependency on transgenic animals.

253 bserved cardiovascular improvements and less dependency on walking assistance, but also partial neuro

254 We validate a distinctive dependency on YAP1 and WWTR1 of the Hippo pathway, where

255 y on multiple software packages with complex dependencies or manually manipulate data for analysis an

256 varies over the soil depth, with this depth dependency persisting across climate and ecological zone

257 Yet, these dependencies pose statistical challenges for analyzing s

258 Cyclin D1 dependency positively correlated with liver cancer sensi

259 avior, whereas alkyne demonstrated a complex dependency; rate inhibition and promotion depend on the

260 (SEM) - GWAS aiming to explore interrelated dependency relationships among phenotypes related to udd

261 FS cells show distinct transcription factor dependencies, relying critically on Otx2.

262 cause of cancer deaths, metastasis-intrinsic dependencies remain largely uncharacterized.

263 o functional genomic features and associated dependencies remain uncommon.

264 frame but their interactions and functional dependency remains unclear.

265 Such technology-dependency and assembly-size dependency require researchers to (i) run multiple polis

266 Drug sensitivity and gene dependency screens demonstrate that these convergent SCN

267 and adaptation delay of the PQ/cycle-length dependency should be included in future non-invasive stu

268 We also discover that OSCCs with WWTR1 dependency signature are significantly associated with b

269 This distance dependency significantly influences the gross reaction k

270 gth in a highly curvilinear fashion with the dependency significantly more curved in females compared

271 fication of risk factors and the analysis of dependency structure among clinical and demographic char

272 These changing dependencies suggest a nuanced view of pleiotropy: biolo

273 catalyst over different length scales, size dependency suggests H atom intercalation as a catalytic

274 T cells exhibit much more profound stiffness dependency than CD8(+) T cells.

275 in 1,2-dicarbonyls showed higher temperature dependency than shorter chain in their reactivity toward

276 st doubt on the validity of several putative dependencies that are currently being targeted in cancer

277 ralogs represent a targetable set of genetic dependencies that are systematically under-represented a

278 rting their alterations reveals EAC acquired dependencies that can be exploited in therapy.

279 iabetic environment confers cancer-selective dependencies that can be therapeutically exploited.

280 he elucidation of the critical intercellular dependencies that constitute the LGG neuroimmune axis pr

281 ectively-lethal compounds revealed metabolic dependencies that defined each subtype.

282 ns within heterogeneous systems can identify dependencies that may not be evident from studying isola

283 ar cell size control mechanisms, we identify dependencies that point to potentially new mechanisms.

284 y (i.e. blood flow x arterial [O(2) ], QO2 ) dependency that slows VO2 kinetics, decreasing CP and VO

285 facilitate reproducibility and avoid system dependencies, the pipeline is contained within a pre-con

286 We verified one of our most promising dependencies, the Werner syndrome ATP-dependent helicase

287 To leverage this dependency therapeutically, we developed a highly potent

288 tion of Features as Images with NEighborhood Dependencies) to arrange high-dimensional vectors in a c

289 AP provides an expansive view of the genetic dependencies underlying HIV infection and can be used to

290 variants partially or fully rescued paralog dependency, underscoring that careful selection criteria

291 unique characteristics including multidriver dependency, variabilities across multiple timescales, no

292 ly found in repeat experiments, although the dependencies vary quantitatively.

293 ive strategy to BET inhibitors to target MYC dependencies via suppression of the AML-selective SE gov

294 Dose dependency was observed at D(2) receptors, with occupanc

295 cell lines representing the extremes in RAS dependency, we identified enriched pathways distinguishi

296 From this Ly49 dependency, we will build a model by which we understand

297 Observed temperature dependencies were quantitatively similar to theoretical

298 hese methods, however, ignore the long-range dependencies when predicting the chromatin profiles beca

299 e model to infer a sparse set of conditional dependencies which reflect not only relationships among

300 e the multi-view features by inferring their dependencies without any additional supervision.