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1 as refractory to ruxolitinib vs ruxolitinib dependent.
2 ilm-promoting brp exopolysaccharide was IamA-dependent.
3 ot VEGF-A, was PPARbeta/delta- and sirtuin-1-dependent.
5 However, the magnitude of antimicrobial MR1-dependent activation remained as potent and polyfunction
6 n cob(II)alamin intermediate via glutathione-dependent alkyltransferase or reductive elimination acti
7 nescent circadian reporter mice that are Cre dependent, allowing the circadian properties of genetica
8 on in the C-repeat/DREB binding factor (CBF)-dependent and CBF-independent cold signaling pathways to
9 ings suggest that PIR-1 modulates both Dicer-dependent and Dicer-independent Argonaute pathways and p
14 rhbeta-gal uptake by the fibroblasts is dose-dependent and saturable and can be competitively inhibit
17 reporter mice; it also exploited both CCL17-dependent and unique CCL17-driven inflammatory pain and
18 ntext (RdRP mice) exhibit constitutive, MDA5-dependent, and quantitatively dramatic upregulation of m
19 subtypes in the mPFC produced dose and time-dependent antidepressant effects in the forced swim and
20 ile conjugation of long-chain Vi generates T-dependent antigens, the conjugates also retain T-indepen
21 ted B cells)-dependent inflammation, caspase-dependent apoptosis, or necroptosis in response to extra
23 h current criteria increased the 5-year time-dependent area under the curve from 0.68 to 0.81 (P=0.00
24 invariant polynomials or sums of environment-dependent atomic contributions, which have recently emer
25 -type (WT), but not FX synapses, by stimulus-dependent ATP synthase beta subunit translation; this in
32 Robust literature has examined social status-dependent brain gene expression profiles across vertebra
33 -independent as well as the pubertal hormone-dependent branching of the mammary epithelium and for pr
34 hat EPEC induces pyroptosis in IECs in a Tir-dependent but actin polymerisation-independent manner, w
35 phosphorylation and is thus exclusively MAT1-dependent by positioning the CDK7 T-loop in its active c
36 as astrocytes, which exhibit norepinephrine-dependent Ca(2+) elevations during vigilance, are not we
38 n human aortic SMCs resulted in increased IP-dependent cAMP production and consecutive facilitation o
39 e discovery of the cadherin family of Ca(2+)-dependent cell-cell adhesion proteins, which play essent
40 CoxFluor enabled the detection of oxygen-dependent changes in COX-2 activity that are independent
44 findings establish a key role for microbiome-dependent circadian GLP-1 secretion in the maintenance o
45 These responses are nucleated via the AKAP5-dependent clustering of P2Y(11)/ P2Y(11)-like receptors,
46 Together our data show that DNA-PK has RNA-dependent, cNHEJ-independent functions during ribosome b
48 of the gut microbiome that elicit a Smarcad1-dependent colitis response, including members of the poo
50 carrier and multicarrier mechanisms for axis-dependent conduction polarity and their identifying band
53 a time dependent variable by generating time-dependent Cox models; HRs at an ELF threshold of 10.51 w
54 t-operative survival was assessed using time-dependent Cox proportional hazard regression analysis an
55 tric cancers that are sensitive to other p53-dependent cytotoxic drugs, also display increased sensit
56 dy [cPRA] class I and/or II >99%, complement-dependent cytotoxicity panel reactive antibody [CDC PRA+
62 s FBXL5 binding to IRP2 to effect its oxygen-dependent degradation, unveiling a novel and previously
63 ite for the stable immobilisation of an NADH-dependent dehydrogenase (i.e. lactate dehydrogenase), vi
68 interactions, which explains the topography-dependent diversity in fibroblast phenotypes observed he
71 release and thus activates the TMEM173/STING-dependent DNA sensor pathway, which results in macrophag
72 he stiffness gradient corresponds to a Wnt5a-dependent domain of fibronectin expression, raising the
77 ere that a Transcriptional Repressor of EIN3-dependent Ethylene-response 1 (TREE1) interacts with EIN
79 study reveals a previously undiscovered Lyn-dependent exit route of flaviviruses in LC3+ secretory o
80 ental niche is associated with the condition-dependent expression of immune function and stress respo
81 c42EP5 affects these functions through SEPT9-dependent F-actin cross-linking, which enables the gener
82 ot fully understood how plants control light-dependent FAS regulation to meet the cellular demand for
83 with experiments that probe proteins in a T-dependent fashion, e.g., for assessing the stability of
86 y thought to reflect the outcome of activity-dependent forms of synaptic plasticity, yet activity-ind
87 broad terms developmental stage and context-dependent functions of lineage-defining transcription fa
88 tors at the plasma membrane to modulate BDNF-dependent gene expression and neuronal dendritic growth
89 ndicate that it is required for Pnr- and Srp-dependent gene expression, suggesting general GATA cofac
91 ailable, the limited overlap of reported p63-dependent genes has made it difficult to decipher the p6
92 bilise target cell activity through activity-dependent global scaling have been observed only within
94 sistance, explaining why short-term, insulin-dependent glucose utilization does not promote insulin r
95 te, also showed a phthiocerol dimycocerosate-dependent growth compromise upon limitation of the corre
96 ults from cancerous cervical cells, K(Ca)3.1-dependent H33258 uptake was rarely observed in epithelia
98 droxylation signals for dioxgen availability-dependent HIF-alpha degradation via the ubiquitin protea
99 e temperature range, paving the way toward T-dependent high-throughput screening applications by HDX-
100 blocker of HCNs-for 24 h resulted in a dose-dependent higher HRV and lower heart rate at 5 days post
101 that EWSR1 is essential for promoting PRDM9-dependent histone methylation and normal meiotic progres
103 in the cochlea, rather cisplatin had a dose-dependent impact on cochlear clock rhythms only after tr
104 (AKT) inhibitor MK2206 blocks the starvation-dependent increase in lysosomal V-ATPase activity withou
106 680I/M680I) FMF knock-in mice exhibited IL-1-dependent increased survival relative to wild-type knock
107 lular detachment, which is followed by SIRT3-dependent increases in SOD2 mRNA during sustained anchor
108 xible decision-making functions in substance-dependent individuals are a consequence of drug-induced
109 ve male NSCLC cell lines demonstrated a dose-dependent induction of linc-SPRY3-2/3/4 following irradi
110 a-light-chain-enhancer of activated B cells)-dependent inflammation, caspase-dependent apoptosis, or
111 d macrophages induce an interleukin-1 (IL-1)-dependent inflammatory cytokine response by recruited mo
113 ministration of (212)Pb-L2 demonstrated dose-dependent inhibition of tumor growth in the PSMA(+) flan
114 ings, an alternative method of modeling time-dependent inhibition that simplifies assay setup and all
116 We have previously demonstrated that copper dependent inhibitors (CDIs), a class of antibiotics that
117 hereas levels of the other incretin, glucose-dependent insulinotropic polypeptide, were not as profou
118 d reduction was revealed to be concentration-dependent interfacial chemistry that only occurs among c
119 capacities, implicating dysregulation of CoA-dependent intermediary metabolism rather than respirator
120 tamalin plays a critical role in the ligand-dependent internalization of mGluR1 and mGluR5, members
122 of its targets, and show how numerous NEDD8-dependent interprotein interactions and conformational c
123 dogenic processing of APP, combined with age-dependent iron elevation in the tissue, increases pro-ox
124 constitutively active form of acetylcholine-dependent K(+) current (I(KACh)), called I(KH); this is
125 Cip1) /p27(Kip1) ) inhibit cyclin and cyclin-dependent kinase (CDK) complex that promotes fibrosis an
127 he Arabidopsis (Arabidopsis thaliana) cyclin-dependent kinase G1 (CDKG1) is necessary for recombinati
128 , cyclin-specific docking motifs help cyclin-dependent kinases (CDKs) phosphorylate different substra
130 zone under Pi deficiency increased with LAC2-dependent lignification, suggesting a direct relationshi
131 ions as a molecular switch that triggers RNA-dependent LLPS in response to a rise in intracellular fr
132 ctly address this question for NMDA receptor-dependent long-term depression (LTD) in the hippocampus.
133 ermined the role of GSK3beta in spike timing-dependent long-term potentiation (tLTP) in the chronic u
134 ELISA)-based assay that uses the temperature-dependent loss of conformational epitopes to measure the
136 urine model, Alp1 elicits helper T (Th) cell-dependent lung eosinophilia that is initiated by the rap
138 C-NAc neurons and corresponding testosterone-dependent male resilience to reduced sucrose preference
140 ing CRISPR-Cas9 technology or in a Postn-Cre-dependent manner (Eprs(flox/+); Postn(MCM/+)) strongly r
141 s in infected macrophages in a concentration-dependent manner and demonstrated activity against Trypa
142 to membranes in a cholesterol concentration-dependent manner and that the binding is facilitated by
143 a from alpha-gal allergic subjects in an IgE-dependent manner suggesting a role for glycolipid in the
144 ermined by the tissue niche in a sex-hormone-dependent manner to limit adipose tissue inflammation.
145 er epithelial progenitor cell line in a dose-dependent manner, achieving far higher efficiency and co
146 e show that Agd3 deacetylates GAG in a metal-dependent manner, and is the founding member of carbohyd
147 levels in both dams and offspring in a dose-dependent manner, but did not change TSH levels, weight,
148 ion and restorative division rates in a dose-dependent manner, leading to tumorous overproliferation
149 w that Zn(2+) inhibits AMPARs in an activity-dependent manner, opening up this pathway as a means to
150 in a TGF-beta receptor/PI3K/protein kinase B-dependent manner, to regulate hepatic acetyl-CoA and cho
169 response in a conductor involves the energy-dependent mean free path of the charge carriers and is a
172 ine N-oxide (TMAO), an intestinal microbiome-dependent metabolite, worsens graft-versus-host disease
173 drenergic stimulation of BAT activates a PKA-dependent mitochondrial Ca(2+) extrusion via the mitocho
176 of GABA and insulin signaling in starvation-dependent modulation of olfactory sensory neuron (OSN) f
177 the question remains as to whether adjuvant-dependent modulation of T(fh) cells enhances HIV-1 vacci
178 ese results identify a plausible temperature-dependent molecular mechanism, which contributes to the
181 ate that both condensin I and II exhibit ATP-dependent motor activity and promote extensive and rever
182 cy of APTi with two gene families, the actin-dependent motor, myosin XI (a,b), and the putative chiti
187 reversible competitive inhibition of CLK1 is dependent on a Michael acceptor forming an irreversible
189 G(i/o) -mediated TRPC4 activation is dually dependent on and bimodally regulated by phosphatidylinos
192 l cord, detailing synaptic diversity that is dependent on developmental stage, anatomical region and
193 ir effector function, was, at least in part, dependent on formation of the microbiome, and consequent
197 omoted capsule retention through a mechanism dependent on its C-terminal lysine residue; its deletion
198 We show that oxygen delivery through PMCs is dependent on its permeability through the polymeric shel
199 The inhibition of Lp-PLA(2) by darapladib is dependent on many factors such as concentrations of dete
200 The pre- and post-division migrations are dependent on microtubules and actin, respectively, and t
201 ent culture that exhibits exponential growth dependent on Mn(II) oxidation to a co-culture of two mic
202 or these species, reproduction appears to be dependent on pollinator identity such that reduced repro
203 the neuronal response rate to ultrasound is dependent on pulse repetition frequency (PRF); and (3) u
205 Management of fisheries that are highly dependent on reefs may need to adapt to declining produc
206 -crystal TiO(2)(110)) was found to be highly dependent on the anchor group, with Ipa establishing a m
208 ffold, and consequently axon pathfinding, is dependent on the expression of an atypical RHO-GTPase, R
209 rted that metastatic pancreatic cancers were dependent on the glucose-metabolizing enzyme phosphogluc
211 n increased growth rate, virulence was still dependent on the mevalonate pathway in 10403S strains ex
212 BAIAP2L2 localization to stereocilia tips is dependent on the motor protein MYO15A and its cargo EPS8
214 rtitions POLE tumors into distinct subgroups dependent on the nature of the POLE allele, its expressi
215 al populations at higher latitudes is highly dependent on the persistence of up-current tropical syst
216 nal TA pair and essentiality of darG(Mtb) is dependent on the presence of darT(Mtb) , but simultaneou
218 ot microbiota under iron deprivation that is dependent on the secretion of plant-derived coumarins.
221 acy of many nucleoside analogues is strongly dependent on their intracellular activation by host cell
223 ort that YtgR repression at P(trpBA) is also dependent on tryptophan by regulating YtgR levels throug
224 inear slopes), PQ intervals were found to be dependent on underlying cycle length in a highly curvili
225 orrelates of frequency were highly electrode dependent: On some electrodes, changes in frequency were
226 nzymes (PHDs) are Fe(II)- and 2-oxoglutarate-dependent oxygenases that act as hypoxia-sensing compone
227 esters and siloxanes suggest that volatility-dependent partitioning processes modulate airborne SVOC
228 would raise the hope for a cure to many P2X7-dependent pathologies, including inflammatory, neurologi
231 sists in muscle, and we asked if this tissue-dependent persistence was linked to MHC expression.
232 Likewise, BMP9/10 treatment induced an ALK1-dependent phenotypic switch from synthetic to contractil
234 Despite the growing interest in activity-dependent plasticity, it is still unclear whether synapt
236 experiments beyond range boundaries, density-dependent population models built from long-term demogra
237 ional B cells, through B cell receptor (BCR)-dependent positive selection of fetally derived precurso
239 sical visual cycle works together with light-dependent processes in both the RPE and neural retina to
240 table complex with Pol II and acts as an ATP-dependent processivity factor that helps Pol II across a
242 Here we implement robust, scalable history-dependent programs by distributing the computational lab
243 derived from human tissue, stimulated HDAC3-dependent proliferation and countered butyrate inhibitio
247 that viperin appears to facilitate ubiquitin-dependent proteasomal degradation of some of the protein
248 of the cyclic adenosine monophosphate (cAMP)-dependent protein kinase (PKA), leading to activation of
251 Here, we report that the Arabidopsis calcium-dependent protein kinase CPK3 is a key regulator of both
252 acellular Ca(2+) through a Ca(2+)/calmodulin-dependent protein kinase II (CaMKII)-mediated mechanism,
255 ring fractionated radiotherapy, using oxygen-dependent quenching of phosphorescence, oxygen probe Oxy
258 n, (5) S-nitrosothiols did not promote NADPH-dependent reduction of tetra-nitro-blue tetrazolium (TNB
259 conclusion, our results reveal distinct PKC-dependent regulation of CF transdifferentiation and prol
260 lite concentrations and considers metabolite-dependent regulation while still retaining many computat
261 2 (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily D, member 2)
267 ransgenic mice expressing a picornavirus RNA-dependent RNA polymerase (RdRP) outside the viral contex
268 AD(+) capping are instead processed into RNA-dependent RNA polymerase 6-dependent small RNAs, resulti
269 demonstrating the importance of demographic-dependent selection in shaping functional phenotypic var
272 a membrane and promotes activation of an SRC-dependent signaling cascade that controls YAP nuclear sh
273 Hypoxia activates hypoxia-inducible factor-dependent signaling, which in turn regulates metabolic r
275 rocessed into RNA-dependent RNA polymerase 6-dependent small RNAs, resulting in their continued turno
279 Within mammalian brain circuits, activity-dependent synaptic adaptations, such as synaptic scaling
283 we show that this system exhibits physiology-dependent temperate dynamics at environmentally relevant
288 terminants of S4 helix motion during voltage-dependent transition from the intermediate to the activa
290 eveal the dynamics and specificity of Parkin-dependent ubiquitylation under endogenous expression con
291 cule manipulation studies of the temperature dependent unfolding and refolding of a titin immunoglobu
292 However, their detection is still heavily dependent upon conventional biochemical assays that reta
294 e radionuclide analogs (RAs) was shown to be dependent upon their chemical speciation in solution, th
296 urrent respiratory infections, revealing age-dependent variation and suggesting a role for IgG glycos
300 on of ER proteins by the KDEL receptor is pH dependent, with binding occurring under acidic condition