ライフサイエンスコーパス: depolarize

1 late to performance and polarized states can depolarize.

2 r environment to conserve sperm's ability to depolarize.

3 BA/glycine inhibition when E(GABAAR) is more depolarized.

4 ion curve of somatic A-type K(+) current was depolarized.

5 e than the relative time that the channel is depolarized.

6 when resting membrane potential was slightly depolarized.

7 as activators of RIS when they are modestly depolarized.

8 in which the emitted radiation is partially depolarized.

9 in [Ca(2+) ]i in cells that were moderately depolarized (11-20 mV) by elevation of [KCl]o (12-20 mm)

10 ells held at hyperpolarized (-40 mV) but not depolarized (-20 mV) voltages.

11 gh light-elicited cholinergic signaling that depolarizes a cholinergic interneuron (cha-lOLP) and hyp

12 old, the membrane voltage will automatically depolarize above the INa threshold due to the large nega

13 data suggest that GABA acquires a transient depolarizing action during recovery from UVN, which pote

14 ly suggesting that GABA acquires a transient depolarizing action in the VN during the recovery period

15 found that ethanol exposure potentiates the depolarizing action of GABA in GABAergic cortical intern

16 s importantly contribute to GDPs, due to the depolarizing actions of GABA early in development.

17 ene regulation to be tailored to the type of depolarizing activity along the somato-dendritic axis of

18 The membrane-depolarizing activity is alleviated by coproduction of t

19 Mechanistically, mitochondria aggregate and depolarize after stress because of loss of activity of t

20 sting induction and suppression of prolonged depolarizing afterpotential.

21 uning characteristics.SIGNIFICANCE STATEMENT Depolarizing afterpotentials (DAPs) are frequently obser

22 shoulder, or a depolarization reminiscent of depolarizing afterpotentials (DAPs) recorded in vitro in

23 locked the ability of GLP-1 agonists and the depolarizing agent KCl to potentiate this.

24 The loss of Cdc42 resulted in a shift to depolarized AML cells that is associated with a decrease

25 (BL) photoactivation of CRY is sufficient to depolarize and activate Drosophila neurons.

26 as inhibitors of RIS when they are strongly depolarized and as activators of RIS when they are modes

27 neuronal membrane potential was at its most depolarized and least variable.

28 s of each entoptic phenomenon generated with depolarized and linearly polarized light were consistent

29 ss, the inner mitochondrial membrane becomes depolarized and permeable to osmolytes, proposedly due t

30 At sleep onset RIS depolarizes and releases FLP-11 to induce a systemic sle

31 ree cycles), occurred when PVs and PYRs were depolarizing and entrained their membrane potential dyna

32 s channels of interest, including dephasing, depolarizing and erasure channels.

33 y of T4 found that the integration of offset depolarizing and hyperpolarizing inputs is critical for

34 ionally control the membrane potential using depolarizing and hyperpolarizing opsins; the ability to

35 ctivated, closed states of the channel under depolarizing and hyperpolarizing transmembrane voltages

36 g voltage-gated ion channels responsible for depolarizing and repolarizing the action potential were

37 neurotransmitters GABA and glutamate rapidly depolarize arcuate kisspeptin neurons and estradiol incr

38 expressing G77R and G83V were significantly depolarized as compared with WTKir4.1, whereas cells exp

39 mparably little research has examined how to depolarize attitudes in people who already embrace extre

40 Application of GABA depolarized axons, but also decreased the amplitude of a

41 nhanced ENaC current contributed to the more depolarized basal membrane potential observed in VP neur

42 In persistently depolarized beta cells from KATP channel knockout (KO) m

43 rly in the pre-ictal period, and can display depolarizing block during the ictal event.

44 ARC glial activation non-specifically depolarizes both AgRP/NPY and POMC neurons but a strong

45 GABAergic current was depolarizing but inhibitory in 8.5 mM K(+), suggesting a

46 BK/Kv became basally active when cells were depolarized by elevated [KCl]o (>12 mm).

47 Surprisingly, dentate PV interneurons are depolarized by GABA signaling, which is in sharp contras

48 nts are insensitive to sound and only weakly depolarized by glutamate release from OHCs.

49 ls only activate in spines that are strongly depolarized by their synaptic input, a process requiring

50 faced particle photothermally induces a cell-depolarizing capacitive current, and predicts that deliv

51 coded by the SCN5A gene, conducts the inward depolarizing cardiac Na(+) current (INa) and is vital fo

52 iomyocyte gap junctional coupling, TGF-beta1 depolarized cardiomyocytes coupled to myofibroblasts by

53 th, and demonstrate that antimicrobials that depolarize cell membranes can benefit cells when the ter

54 ffect mediated by the emergence of a rapidly depolarizing cell population, and the expression of hERG

55 ce, inhibition of Sty1 converts non-growing, depolarized cells into growing, polarized cells.

56 ength light, the same electrical stimulation depolarizes cells instead of causing hyperpolarization.

57 We showed that depolarizing changes in the presynaptic holding potentia

58 d CaMKII had enhanced persistent current and depolarized channel inactivation resembling the properti

59 o-threshold of p ~ 0.50 under a single qubit depolarizing channel applied to all qubits.

60 be searched, when decoherence is modelled by depolarizing channels' deleterious effects imposed on th

61 leotide-gated (CNG) channel and stimulates a depolarizing chloride current by opening the olfactory C

62 Here we show that, in mice, 5-HT depolarizes cholinergic interneurons (ChIs) of the dSt w

63 er direct control, we used densely-expressed depolarizing (ChR2) or hyperpolarizing (eArch3.0, eNpHR3

64 Aergic-mediated feed-forward inhibition, the depolarizing component of spikelets transiently increase

65 The voltage sensor adopts a depolarized conformation, and the pore is closed.

66 this structure, the voltage sensors adopt a depolarized conformation, and the pore is open.

67 at appears to lock the voltage sensor in its depolarized conformation.

68 e-type releaser at DAT that evoked an inward depolarizing current and calcium influx, whereas other a

69 ts due to a severe reduction of a muscarinic depolarizing current and M1 receptor internalization.

70 activation might cause a sharp escalation in depolarizing current and underlie the steep initial rise

71 the number of action potentials evoked by a depolarizing current at 2X rheobase in neurons from CCD

72 e sodium current (INa) that provides a rapid depolarizing current during the upstroke of the action p

73 id not affect spike frequency in response to depolarizing current injection or hyperpolarization-indu

74 the voltage-response to hyperpolarizing and depolarizing current injection.

75 fying, and analyzing the firing responses to depolarizing current injections for every hippocampal ne

76 The maximum spike frequency evoked by depolarizing current injections in Scn8a(N1768D/+) CA1,

77 e majority of cells preset at -80 mV, 500 ms depolarizing current injections to cells led to a brief

78 by increased neuronal spiking in response to depolarizing current injections, whereas blockade of Kv7

79 the number of action potentials elicited by depolarizing current pulses was significantly increased

80 ion of TRN neurons, synaptic inputs or brief depolarizing current steps led to long-lasting plateau p

81 When driven by various forms of depolarizing current stimulus, Re neurons display consid

82 ted sodium channel Na(V)1.4 conducts the key depolarizing current that drives the upstroke of the ske

83 esponse increased indefinitely with injected depolarizing current, but reached saturation with chemic

84 on in vascular myocytes enables a persistent depolarizing current, leading to constriction of coronar

85 tion of an M1-coupled, pirenzepine-sensitive depolarizing current, which appeared to be, at least in

86 sponses to hyperpolarizing (P < 0.00007) and depolarizing currents (P < 0.001) in threshold electroto

87 ber of action potentials that were evoked by depolarizing currents as well as maximal firing rates we

88 e 2 setting through (1) providing additional depolarizing currents during action potential plateau ph

89 edictions and experimental results: net soma depolarizing currents increased choice hysteresis, while

90 The SIAs depolarize during flipping and their optogenetic activat

91 Sleep-active neurons depolarize during sleep to suppress wakefulness circuits

92 t (AIS) showed that axo-axonic synapses were depolarizing during this period.

93 nels only becomes important when the cell is depolarized (e.g. by a high external K(+) concentration)

94 no such effect was observed when placing the depolarizing electrode over lateral PFC.

95 We placed the soma depolarizing electrode over medial frontal PFC.

96 ommon spectroscopic characteristics, such as depolarized emission, viscosity-dependent radiationless

97 idification, crucial for ClC-5 activation by depolarizing endosomes.

98 ells equilibrated with FMP-Red-Dye exhibited depolarized equilibrium membrane potentials compared wit

99 de bifurcation, the system can automatically depolarize even in the absence of INa to voltages higher

100 1632G mutation hyperpolarizes activation and depolarizes fast-inactivation, both gain-of-function att

101 ring neurons with the capacity to burst when depolarized from a hyperpolarized membrane potential.

102 llular chloride overload, revealed through a depolarized GABA reversal potential and increased expres

103 ur findings show that early post-SE abnormal depolarizing GABA and p75(NTR) signaling fosters a long-

104 s of the K(+)/Cl(-) cotransporter KCC2 and a depolarizing GABAA receptor-mediated synaptic component

105 fuse intracerebrally a specific inhibitor of depolarizing GABAergic transmission as well as a functio

106 vivo also change the type of excitability: a depolarized gamma-Aminobutyric acid receptor (GABAR) rev

107 rewiring of excitatory circuits, an abnormal depolarizing gamma-aminobutyric acidergic (GABAergic) dr

108 Our simulations suggest that depolarizing GGN at its input branch can globally inhibi

109 ent individual principal cells from strongly depolarizing granule cells, which likely discharge in re

110 ation (EDH) characteristic of arteries, LECs depolarized (>15 mV) to either ACh or TRPV4 channel acti

111 Unlike the depolarized HCN channel, the S4 helix is displaced towar

112 13R expression is uniquely associated with a depolarizing, HCO3(-) independent, Cl(-) -conductance in

113 on of these GABA receptor anion channels can depolarize horizontal cells and increase cleft acidity v

114 Preconditioning the cell model with depolarizing/hyperpolarizing prepulses allowed us to hig

115 tracellular Na(+) (Na(i)) that decreases the depolarizing I(NCX) thereby suppressing the action poten

116 enerated in vitro from progenitors exhibited depolarizing, immature GABA responses, like those of ear

117 how that BK/Kv are activated as glomus cells depolarize in response to hypoxia, which then limits the

118 ve a negative resting membrane potential and depolarize in synchrony with cardiomyocytes.

119 that the reversal potential for GABA is more depolarized in mutant mice, but is restored by applicati

120 Resting membrane potential was more depolarized in Pitx2c(+/-) atria, and TWIK-related acid-

121 and miR-34c, which subsequently targeted key depolarizing (INa) and repolarizing (Ito) currents alter

122 ed with larger persistent sodium current and depolarized inactivation in neurons from F1.Q54 animals.

123 easing activity during behavior and directly depolarizing inhibitory cells.

124 POm, however, more robustly depolarized L2/3 cells and, when paired with peripheral

125 A depolarizing 'leak' current supports this firing pattern

126 rt in brain slices that activation of nAChRs depolarizes LHb cells and robustly increases firing, and

127 Depolarized light images were computed using a polarizat

128 atrial cardiomyocyte monolayers expressing a depolarizing light-gated ion channel (Ca(2+)-translocati

129 -protein-coupled receptor called melanopsin, depolarize like photoreceptors of invertebrates such as

130 higher action potential threshold and a more depolarized membrane potential, thus reducing membrane e

131 the magnitude of tonic current generated at depolarized membrane potential-a property associated wit

132 lular calcium ([Ca(2+)]i) and recovered with depolarized membrane potentials or elevated [Ca(2+)]i Co

133 nsitive Vglut3(lineage) neurons to have more depolarized membrane potentials, lower firing thresholds

134 ing K(+) channels conduct greater current at depolarized membrane potentials, whereas inward rectifie

135 nd Mgat1KO Ca(v) activity is shifted to more-depolarized membrane potentials.

136 us Ca release activates inward current which depolarizes membrane potential (Vm) and can trigger acti

137 side the RF increases synaptic activity that depolarizes membrane potential responses at the behavior

138 rrent clamp, block of BKCa current increased depolarizing membrane potential excursions, raising the

139 amped horizontal cells, BKCa channels subdue depolarizing membrane potential excursions, reduce the a

140 Resulting depolarization conducts to SMCs, depolarizing membrane potential, activating L-type Ca(2+

141 In response to a depolarizing membrane potential, the S4 helix undergoes

142 nction pharmacologically or by gene knockout depolarizes microglia, which decreases microglial ramifi

143 , we found that it was also able to directly depolarize mitochondria.

144 and 2-deoxyglucose, a glycolytic inhibitor, depolarized mitochondria after respiratory inhibition, w

145 tif or by deletion of Tom7, is imported into depolarized mitochondria and cleaved by the OMA1 proteas

146 o assess the timing of parkin recruitment to depolarized mitochondria and its modulation by kenpaullo

147 insufficient vesicle induction, accumulating depolarized mitochondria and PINK1.

148 We found that TILs accumulated depolarized mitochondria as a result of decreased mitoph

149 ated proteins were sequentially recruited to depolarized mitochondria followed by sequestration into

150 ubiquitin ligase and mitophagy effector, on depolarized mitochondria in neonatal rat cardiac myocyte

151 The removal of damaged or depolarized mitochondria occurs via mitophagy, in which

152 The analysis of depolarized mitochondria reveals that PINK1/parkin-media

153 Enforced accumulation of depolarized mitochondria with pharmacological inhibitors

154 e find that TBK1 is corecruited with OPTN to depolarized mitochondria.

155 FN-I signaling dysregulates iron metabolism, depolarizes mitochondrial membrane potential, and induce

156 sting K(+) conductance allowing the cells to depolarize more readily to a variety of excitable stimul

157 Basolateral membranes of DCT cells were depolarized, nearly devoid of conductive potassium trans

158 dullary respiratory networks that is able to depolarize neurons of the parafacial respiratory group d

159 d extracellular nTS glutamate concentration, depolarized neurons and enhanced spontaneous EPSCs.

160 In both cell types, depolarizing neurons increased the size of voltage fluct

161 inguish whether a sympathetic nerve fibre is depolarized or not.

162 post-trial activity decay through simulated depolarizing or hyperpolarizing network stimulation.

163 oltage sensor domains, in response to either depolarizing or polarizing transmembrane voltages, to op

164 Activation of tanycytes ex vivo depolarized orexigenic (neuropeptide Y/agouti-related pr

165 e potassium in the synaptic cleft, and would depolarize other hair cells enveloped by the same neurit

166 Depolarizing pFL neurons produced active expiration at r

167 odium (Nav) channels are responsible for the depolarizing phase of the action potential in most nerve

168 may hold even greater potential as tools for depolarizing political debates and resolving policy disp

169 II UBCs because it was initiated from a more depolarized potential compared to normal cells.

170 Early network giant depolarizing potential oscillatory activity was compromi

171 polarized resting membrane potentials; these depolarized potentials cause cardiac arrhythmia; however

172 oltage dependence is shifted by 10 mV toward depolarized potentials with no change on the deactivatio

173 At depolarized potentials, the input-output function for sy

174 rectifying K(+) channels are reduced at more depolarized potentials.

175 activation gating was slowed and shifted to depolarized potentials.

176 the threshold for channel activation to more depolarized potentials.

177 threshold of patient-derived neurons to more depolarized potentials.

178 rrent that prolongs the synaptic response at depolarized potentials.

179 this activity is observed in vitro as giant depolarizing potentials (GDPs) during the first postnata

180 taneous network events, referred to as giant depolarizing potentials (GDPs) in the hippocampus.

181 ated nicotinic ACh receptor (nAChR)-mediated depolarizing potentials and muscarinic ACh receptor (mAC

182 rticocallosal neurons lacking mAChR-mediated depolarizing potentials did not show persistent firing.

183 These prolonged depolarizing potentials generated persistent firing in c

184 rons, ACh generated prolonged mAChR-mediated depolarizing potentials in corticocollicular neurons.

185 re hyperexcitable and generated long-lasting depolarizing potentials with bursts of action potentials

186 ous activities appeared in the form of giant depolarizing potentials.

187 s, ACh release also generated nAChR-mediated depolarizing potentials.

188 When UV was applied at progressively more depolarized preopen holding potentials, cross-linking of

189 and slowing of deactivation in response to a depolarizing prepulse.

190 ) APD(90) in response to hyperpolarizing and depolarizing prepulses, respectively, whereas other mode

191 on was voltage-independent and unaffected by depolarizing prepulses.

192 oltage-dependent and transiently relieved by depolarizing prepulses.

193 entries using Grover's QSA at an aggressive depolarizing probability of 10(-3), the success probabil

194 e receptor agonist (4-chloro-meta-cresol) or depolarizing pulses were used.

195 parated signals, i.e., the polarized and the depolarized Raman signal.

196 adiabatic compression and become completely depolarized, releasing surface screening charge with den

197 rent-induced firing threshold, and decreased depolarizing response to NMDA in deep-layer PL-PFC neuro

198 and OFF synaptic layers, but with a pure ON (depolarizing) response to light.

199 n of GABAergic cortical neurons is driven by depolarizing responses to ambient GABA present in the co

200 action potentials (APs) and an unstable and depolarized resting membrane potential (RMP) because of

201 -3 function in mHb ChNs, which likely led to depolarized resting membrane potential and increased spo

202 embrane excitability, but was accompanied by depolarized resting membrane potential in mHb ChNs.

203 gs showed significantly decreased amplitude, depolarized resting membrane potential, increased durati

204 ent-clamp experiments small neurons had more depolarized resting membrane potentials, and required sm

205 cardiomyocytes show both hyperpolarized and depolarized resting membrane potentials; these depolariz

206 g remains immature in both DS models, with a depolarized reversal potential for GABA(A)-evoked curren

207 In summary, EGFR signaling can depolarize RIS by an indirect mechanism through activati

208 C-Raf and downstream ERK activity maintain a depolarized RMP and nociceptor hyperactivity after SCI,

209 rebound or post-stimulation recovery, and no depolarizing sag.

210 s define the interface between polarized and depolarized segments of mitochondria and can rescue the

211 -frequency plateau bursts, associated with a depolarizing shift in action potential threshold.

212 Ser-561 and Ser-641/Thr-642 recapitulate the depolarizing shift in activation and reduction in curren

213 According to computational modeling, a depolarizing shift in GABA reversal potential (EGABA) an

214 physically distinct K(+) currents revealed a depolarizing shift in the activation of a rapidly inacti

215 istent currents by 72% and produces a 5.8-mV depolarizing shift in the voltage dependence of activati

216 nction modulator that inhibits the canonical depolarizing shift in the voltage dependence of HCN4 in

217 ts revealed that L203P at S4 induces a large depolarizing shift in voltage dependence of K(v)7.2 chan

218 Removal of the beta3-ECD abrogated both the depolarizing shift of steady-state inactivation and the

219 fect the previously observed beta3-dependent depolarizing shift of V (1/2) of steady-state inactivati

220 d with loss-of-function effects, including a depolarizing shift of voltage-dependent activation or a

221 lts in inward transient cation currents that depolarize smooth muscle cells, leading to vasoconstrict

222 Persistently depolarizing sodium (Na(+)) leak currents enhance electr

223 out preventing further prolongation by brief depolarizing somatic prepulses.

224 While acute ACh application can modestly depolarize some Golgi cells, the net effect of longer, o

225 mesenchyme switches from a hyperpolarized to depolarized state during early chondrocyte differentiati

226 (VSD), both in a hyperpolarized state and a depolarized state resulting from voltage-dependent confo

227 age-dependence of channel activation so that depolarizing steps evoke larger sodium currents.

228 ion, rather than to the timing of subsequent depolarizing steps, suggesting that cholinergic signal t

229 CO2/H+ changes), in the absence of external depolarizing stimulation, showed no signs of postinhibit

230 ormally governs cortical neuron responses to depolarizing stimuli by opposing prolonged discharges an

231 porting persistent firing modes triggered by depolarizing stimuli following cholinergic receptor acti

232 T-channels switched burst firing with lower depolarizing stimuli to regular spiking, and fully aboli

233 entate granule neurons in response to strong depolarizing stimuli was also observed.

234 xhibited an inability to properly respond to depolarizing stimuli, demonstrating that Na(V)1.7 is a k

235 rotein densin and CaMKII and that outlasts a depolarizing stimulus by seconds.

236 il current of up to 8 s duration following a depolarizing stimulus in both tsA-201 cells and male rat

237 enings that can last for seconds following a depolarizing stimulus train.

238 utward tail current of up to 8 s following a depolarizing stimulus.

239 litation of channel activity that outlasts a depolarizing stimulus.

240 The depolarized structural model is also consistent with the

241 of Parkin, VCP/p97, p62/Ref(2)P and Atg8a to depolarized swollen mitochondria.

242 In contrast, when the dendrite is depolarized, T-type VGCCs and A-type VGKCs are inactivat

243 lexiform layers after glutamatergic synapses depolarize TH cell dendrites in the inner plexiform laye

244 SOD MNs exhibited an E(GABAAR)10 mV more depolarized than in WT MNs associated with a KCC2 reduct

245 glucose metabolism alone is insufficient to depolarize the cell and evoke GLP-1 secretion in the mod

246 ation since incoming action potentials would depolarize the dendrite at multiple sites within a brief

247 vating non-selective cationic channels which depolarize the membrane potential.

248 Local CRFR2 activation by urocortin 3 depolarized the cells, increased the neuronal input resi

249 y abolished basolateral K(+) conductance and depolarized the DCT membrane, but also abrogated the sti

250 Mechanistically, GABA depolarized the majority of sensory neuron somata, yet p

251 sed the GluN1/GluN3A equilibrium current and depolarized the membrane in a glycine concentration-depe

252 resting around -160 to -180 mV, reproducibly depolarized the membrane potential by 95 mV on average.

253 el, decreased basolateral K(+) currents, and depolarized the membrane.

254 Interestingly, Abeta-CEL16&28 had depolarized the mitochondrial membrane potential, wherea

255 The elevated potassium concentration also depolarized the postsynaptic neuron by altering ion perm

256 CXCL12 depolarized the resting membrane potential, decreased th

257 Blocking SK channels with apamin depolarized the resting membrane potential, reduced rest

258 f quanta released, elevates [K(+) ]cleft and depolarizes the afferent to potentials at which smaller

259 H2A enhances AMP-induced pores, depolarizes the bacterial membrane potential, and impair

260 Blocking K(ATP) channels pharmacologically depolarizes the beta-cell plasma membrane and terminates

261 dition, deletion of TrkA in Escherichia coli depolarizes the cell, suggesting that the TrkH-TrkA comp

262 ducing a flux of Na(+) and/or K(+) ions that depolarizes the cell, thus modulating cellular Ca(2+) en

263 o the Escherichia coli periplasm and that it depolarizes the cytoplasmic membrane.

264 he climbing fiber synaptic input transiently depolarizes the dendrite of cerebellar Purkinje neurons

265 This current depolarizes the hair cell and triggers the calcium-induc

266 tials in response to a current stimulus that depolarizes the membrane above an excitation threshold.

267 In addition, CO-EtOAc depolarizes the mitochondrial membrane and decreases the

268 In addition, we also found that shizukaol F depolarizes the mitochondrial membrane and inhibits resp

269 Elevated potassium depolarizes the postsynaptic afferent by altering ion pe

270 ide-gated (HCN) channels, and contributes to depolarizing the afferent to potentials where a single E

271 y of ENaCs, which augments synaptic drive by depolarizing the basal membrane potential close to the a

272 rast, IRAG causes a gain of HCN4 function by depolarizing the basal voltage dependence in the absence

273 pulating the endogenous bioelectric state by depolarizing the injured tissue during the first 3 h of

274 on potential firing to current injection and depolarizing the membrane potential.

275 intains viability during oxygen depletion by depolarizing the membrane.

276 hore that uncouples the mitochondria without depolarizing the plasma membrane, as a lead compound for

277 g the firing rate and regularity, as well as depolarizing the resting membrane potential in mHb ChNs

278 oss-linked 300 kDa increased excitability by depolarizing the resting membrane potential, and decreas

279 l enhancement is accomplished by selectively depolarizing the xenon within a cage molecule which, upo

280 here transduction currents are sufficient to depolarize them to voltages necessary for calcium influx

281 cted selectively to increase their activity, depolarizing these neurons and increasing their firing r

282 Sleep requires sleep-active neurons that depolarize to inhibit wake circuits.

283 itial membrane potential, the climbing fiber depolarizing transient activates two distinct sets of ch

284 e that PIN-PMN-PT crystals became completely depolarized under 3.9 GPa compression.

285 ons display synchronized transitions between depolarized Up states and hyperpolarized Down states.

286 ia and 4 unaffected control individuals were depolarized using potassium chloride.

287 ardiac mitoBK(Ca) displayed a low P(o) and a depolarized V(1/2) of activation (+47 mV at 12 um matrix

288 s from n = 5 different hearts), displaying a depolarized V(1/2) of activation (+47 mV in 12 um matrix

289 lf-maximal Kv11.3 channel activation to more depolarized values and reduced its voltage sensitivity.

290 sponses in V1 to a stationary scene, 2) that depolarized VIP cells enhance V1 responses to moving obj

291 ength to overcome a weakened current sink to depolarize Vm and trigger action potentials.

292 Local Ca waves depolarized Vm in HF but not CTL hearts, suggesting weak

293 KAT1 displays a depolarized voltage sensor, which interacts with a close

294 y describes one physiological form of KCNQ1, depolarized voltage sensors with a closed pore in the ab

295 onist during afferent stimulation trains and depolarizing voltage steps caused a significant, sustain

296 s study observed residual STOC production at depolarized voltages that was independent of CaV 1.2 and

297 (IKur) inactivates slowly but completely at depolarized voltages.

298 Being activated by depolarizing voltages and increases in cytoplasmic Ca(2+

299 JZTx-27 was more efficacious at weaker depolarizing voltages and significantly slowed the activ

300 is not dependent on the level of maturation (depolarizing vs. hyperpolarizing) of postsynaptic GABAA