ライフサイエンスコーパス: depolymerization

1 e disassembly rate (corresponding to F-actin depolymerization).

2 reatment and is insensitive to Lat B-induced depolymerization.

3 facilitate tracking during rapid microtubule depolymerization.

4 pletion reduce detyrosination independent of depolymerization.

5 y RSK2 reduced stathmin-mediated microtubule depolymerization.

6 ilament ends available for polymerization or depolymerization.

7 ia actomyosin contraction coupled with actin depolymerization.

8 fulfill a critical targeting function in PCW depolymerization.

9 been suggested to generate stress and drive depolymerization.

10 egulated in part by actin polymerization and depolymerization.

11 chanism involving Kif24-mediated microtubule depolymerization.

12 inutes via combined fibril fragmentation and depolymerization.

13 elongation, severing, and WH2 motif-mediated depolymerization.

14 ound to actin filaments stabilizes them from depolymerization.

15 plastic deformation and reprocessing without depolymerization.

16 cooperate to stabilize filaments by slowing depolymerization.

17 an also sever filaments and accelerate their depolymerization.

18 ers whose disassembly is maintained by actin depolymerization.

19 lkene acid structure formed during enzymatic depolymerization.

20 een LPMO and hydrolytic enzymes in cellulose depolymerization.

21 (2+)-catalyzed Fenton-type and photochemical depolymerization.

22 e of the mitotic checkpoint upon microtubule depolymerization.

23 and protect them against kinesin-13-induced depolymerization.

24 ement to microtubule (MT) polymerization and depolymerization.

25 re movement coupled to MT polymerization and depolymerization.

26 d at sites of microtubule polymerization and depolymerization.

27 t synergy with hydrolytic enzymes in biomass depolymerization.

28 actor of the efficiency of enzymatic biomass depolymerization.

29 vels of active cofilin, which mediates actin depolymerization.

30 s to the direct lignin biomass upgrading and depolymerization.

31 unipolar bundles and stabilizes them against depolymerization.

32 lating cofilin to inhibit actin severing and depolymerization.

33 ction in energy dissipation upon microtubule depolymerization.

34 ctin) by inhibiting actin polymerization and depolymerization.

35 s at a rate 330-fold faster than spontaneous depolymerization.

36 d severing or nocodazole-induced microtubule depolymerization.

37 n unknown product coming from polysaccharide depolymerization.

38 mining the maximum monomer yield from lignin depolymerization.

39 s are integrated into the microtubule before depolymerization.

40 een alternating phases of polymerization and depolymerization.

41 ctor in the efficiency of the acid-catalyzed depolymerization.

42 Microtubule depolymerization abolished uptake of complement-opsonize

43 ctivity, and seven proteins showed polyester depolymerization activity against polylactic acid and po

44 Cofilin-1-severing/depolymerization activity is negatively regulated by pho

45 s model of filament formation, bundling, and depolymerization after GTP hydrolysis, which involves a

46 ensional growth, latrunculin-A-induced actin depolymerization and apoptosis, and cell line transfecti

47 Moreover, actin and microtubule depolymerization and changing chromatin condensation alt

48 Efficient depolymerization and deoxygenation of lignin while retai

49 -actin bands develop increased resistance to depolymerization and exceptional stability that parallel

50 trunculin B, a reagent known to induce actin depolymerization and impair bulk and ultrafast endocytos

51 and leading to faster glucose-induced actin depolymerization and increased insulin release.

52 Microtubule depolymerization and kinesin-related motors contribute t

53 Calcium acts by promoting actin depolymerization and localizing actin polymerization and

54 underlies Golgi dispersal during microtubule depolymerization and mitosis.

55 ation, negative regulation of actin filament depolymerization and negative regulation of protein comp

56 acetylated region of microtubules to prevent depolymerization and rescue polymerization.

57 reating a boundary that prevents microtubule depolymerization and rescues microtubule polymerization.

58 n of valuable products emanating from lignin depolymerization and the successful execution of such st

59 s recapitulates all aspects of reversible MT depolymerization and transient formation of +TIPs bars.

60 ls where aging or mechanical damage triggers depolymerization, and orthogonal conditions regenerate t

61 e expression by leptin is dependent on actin depolymerization, and pharmacologically induced actin de

62 gement of actin filaments by polymerization, depolymerization, and severing is important for cell loc

63 Polymerization and depolymerization are especially important for gliding mo

64 Here we investigate length-dependent depolymerization as a mechanism of length control.

65 by establishing colcemid-induced microtubule depolymerization as a sensitive assay, we examined the c

66 investigations into lignin's degradation and depolymerization as related to its stereochemical consti

67 g actin cosedimentation, polymerization, and depolymerization assays, along with total internal refle

68 We demonstrate that force suppresses depolymerization at both plus and minus ends, rather tha

69 o one-dimensional diffusion (ODD) and induce depolymerization at the MT ends.

70 vitro experiments to investigate changes in depolymerization based on the presence of islands of unc

71 ommonly used acid hydrolysis for sugar chain depolymerization before monomer quantification.

72 Actin depolymerization blocks the increase in spEPSC amplitude

73 b5 knockout did not influence cortical actin depolymerization but affected protein kinase C activity

74 downstream of G protein signaling and actin depolymerization but upstream of insulin granule release

75 that divalent cations inhibit rescue during depolymerization, but not during polymerization.

76 linkages, rendering them more susceptible to depolymerization by acid-catalyzed cleavage of aryl-ethe

77 est that SEPT9 protects actin filaments from depolymerization by cofilin and myosin and indicate a me

78 significantly reduces the extent of F-actin depolymerization by cofilin.

79 e endo-1,6-beta-glucanase in 1,6-beta-glucan depolymerization by deleting bt3312, which prevented the

80 Consistently, microtubule depolymerization by nocodazole blocks granule withdrawal

81 wn cells also display enhanced resistance to depolymerization by nocodazole.

82 Finally, we recapitulate lamina depolymerization by PLK-1 in vitro demonstrating that LM

83 bulin curvature-sensing model of microtubule depolymerization by the budding yeast kinesin-8, Kip3.

84 Growing microtubules are protected from depolymerization by the presence of a GTP or GDP/Pi cap.

85 Length dependent depolymerization can arise from a concentration gradient

86 Its depolymerization can be accomplished through hydrogenoly

87 l ER, whereas locally increasing microtubule depolymerization causes exaggerated asymmetric spindle p

88 Following cyclin B degradation, ipMT depolymerization ceases so the sliding ipMTs can push th

89 We demonstrate that depolymerization continues in the posterior hindgut, and

90 an exponential decay in the kinetic rate of depolymerization corresponding to the relative level of

91 microtubule nucleation and growth, mediates depolymerization coupled pulling at plus ends, and bundl

92 ex is required for a distinct substep of the depolymerization-coupled pulling mechanism.

93 to rebound during protein polymerization and depolymerization cycles.

94 Depletion of either SNX27 or VPS35 or actin depolymerization decreased the rate of PTHR recycling fo

95 creased the rates of both polymerization and depolymerization, decreased the amount of polymer assemb

96 monstrate novel derivatization chemistry for depolymerization/desulfation and alkylation of HS based

97 The nature of microtubule depolymerization dictates the type of shape transformati

98 perties, heparin source material and mode of depolymerization, disaccharide building blocks, fragment

99 lls, consistent with rapid MT polymerization/depolymerization during cell proliferation.

100 table versions of LMN-1, which affect lamina depolymerization during mitosis, is sufficient to preven

101 in a distinctly polar manner to catastrophic depolymerization (dynamic instability) both in vitro and

102 it could be hypothesized that polymerization-depolymerization dynamics may be an additional signal th

103 azole-, colchicine-, and vincristine-induced depolymerization events of tyrosinated microtubules in r

104 Mechanistically, cold-induced MT depolymerization experiments demonstrated a hyper-stabil

105 cell biology-based analyses, show that actin-depolymerization factor 4 (ADF4) is a physiological subs

106 icate that Aip1 is a cofilin-dependent actin depolymerization factor and not a barbed-end-capping fac

107 sphorylation and inactivation of the F-actin depolymerization factor cofilin to induce TNT formation.

108 rin signaling through FAK and cofilin (actin depolymerization factor) is necessary to promote synapti

109 ain length and the kinetics of intracellular depolymerization for targeted delivery.

110 Additionally, it acts as an enhancer of depolymerization for taxol-stabilized tubulin.

111 s also compared with LESA-HRMS without prior depolymerization for the analysis of the surface of the

112 of GlpQ, revealed distinct mechanisms of WTA depolymerization for the two enzymes; GlpQ catalyzes exo

113 o a stochastic process of polymerization and depolymerization from their plus ends termed dynamic ins

114 liary length control through its microtubule depolymerization function.

115 , which undergo cycles of polymerization and depolymerization generating straight and curved microtub

116 MAP20 suppresses microtubule depolymerization; however, unlike the animal TPX2 counte

117 le stochastically between polymerization and depolymerization, i.e. they exhibit "dynamic instability

118 opment of a photocatalytic system for lignin depolymerization in a continuous microreactor is a super

119 in washout experiments to induce microtubule depolymerization in a controlled manner at different tim

120 mers can alter the mechanism and kinetics of depolymerization in a manner consistent with promoting r

121 -induced ciliary resorption and cold-induced depolymerization in ARMC9 and TOGARAM1 patient cell line

122 actin filaments in axonal GCs, preventing MT depolymerization in F-actin-rich areas.

123 e cooperative interactions to cause complete depolymerization in humid conditions.

124 , or colchicine; and 6) leads to microtubule depolymerization in PC3 cells.

125 resent a rather counterintuitive role of BAR depolymerization in regulating the shape evolution of ve

126 on microscopy (dSTORM), we show that F-actin depolymerization in spines leads to a breakdown of the n

127 reward, is vulnerable to disruption by actin depolymerization in the basolateral amygdala complex (BL

128 Partial depolymerization in vitro of nonphosphorylated smooth mu

129 on of a growth pause just before microtubule depolymerization, indicating an important role of the ma

130 th latrunculin A, a drug that leads to actin depolymerization, induces dispersal of the Cdc42 module

131 ors: active interfaces transduce microtubule depolymerization into mechanical work, and passive inter

132 cs, and help explain how rapid actin network depolymerization is achieved in cells.

133 t of fundamentally new approaches for lignin depolymerization is challenged by the complexity of this

134 easing their density; such local microtubule depolymerization is necessary for GSIS, likely because g

135 oes not mimic MB, demonstrating that F-actin depolymerization is not responsible for unidirectional t

136 growth persistence is reduced, inhibition of depolymerization is sufficient for pseudopod maintenance

137 ization, and pharmacologically induced actin depolymerization is sufficient to enhance Kv2.1 surface

138 The role of photocatalysis in such lignin depolymerizations is questionable as the dissolution pro

139 lymerization and 'curved' during microtubule depolymerization) is an essential requirement for accura

140 This preferential binding protracted the depolymerization kinetics of Lys48-linked ubiquitin chai

141 and PS side chains also play a minor role in depolymerization kinetics, which is discussed.

142 Current models attribute oxidative depolymerization largely to the activity of extracellula

143 e microtubules grow faster and transition to depolymerization less frequently compared with brain mic

144 However, after depolymerization, low molar mass polyolefins contained s

145 kbone appears to occur through an end-to-end depolymerization mechanism as evidenced by size exclusio

146 tor, supporting a collective force-dependent depolymerization mechanism that unifies the so-called "b

147 In this study, we introduce a new on-surface depolymerization method coupled to liquid extraction sur

148 Practical, high-yield lignin depolymerization methods could greatly increase biorefin

149 cates chemical conversion efforts, and known depolymerization methods typically afford ill-defined pr

150 of C. difficile adherence regulated by actin depolymerization, microtubule restructuring, subsequent

151 Blocking actin depolymerization, Na(+)/H(+) exchange, PI3K, and Pak1 ki

152 Quantitative depolymerization occurs under thermodynamic conditions (

153 ular weight were recovered from fermentative depolymerization of a native EPS produced by Pseudomonas

154 gulated through cycles of polymerization and depolymerization of actin cytoskeletal networks.

155 Nucleocapsid transport was arrested upon depolymerization of actin filaments (F-actin) and inhibi

156 lve two key processes: 1) polymerization and depolymerization of actin filaments and 2) remodeling of

157 dynamic behavior, such as polymerization and depolymerization of actin filaments in response to intra

158 Depolymerization of actin filaments is vital for the mor

159 contrast, phalloidin, an agent that prevents depolymerization of actin filaments, inhibits Nrf2 trans

160 actin-spectrin binding and cofilin-mediated depolymerization of actin filaments, play an essential r

161 ndant actin-severing protein involved in the depolymerization of actin filaments.

162 ily function is to regulate the severing and depolymerization of actin filaments.

163 Depolymerization of actin led to resumed granule secreti

164 Upon efficient depolymerization of actin, pearls of variable size are f

165 ary actin-ADP-ribosylating toxin that causes depolymerization of actin, thereby inducing formation of

166 s positively to facilitate the 2,4-D-induced depolymerization of actin.

167 the cytoskeleton protein, alpha-Tubulin, and depolymerization of alpha-Tubulin led to the intracellul

168 symmetry; however, how the cortex causes the depolymerization of astral microtubules during asymmetri

169 Finally, the complete depolymerization of BBs into alpha-cyclopentenyl-PS allo

170 The depolymerization of bottlebrush (BB) polymers with varyi

171 lefin polymerization, alkane hydrogenolysis, depolymerization of branched polymers, ring-opening poly

172 uctural and mechanistic aspects of oxidative depolymerization of cellulose by PMOs and considers thei

173 achieved an almost 100% recovery and partial depolymerization of chitin from shrimp shell waste (SSW)

174 most intricate nanomachines dedicated to the depolymerization of complex carbohydrates.

175 The depolymerization of complex glycans is an important biol

176 charide reserves provides a facile route for depolymerization of constituent polysaccharides into sim

177 port here the first example of hydrogenative depolymerization of conventional, widely used nylons and

178 apid destruction of the device due to acidic depolymerization of cPPA.

179 of Abeta fibrillar polymerization and direct depolymerization of existing Abeta fibrils.

180 focal microscopy, we found that AMPK induced depolymerization of F-actin (filamentous actin).

181 Depolymerization of F-actin abrogated exclusion.

182 The central domain inhibits the depolymerization of F-actin and is also responsible for

183 ingly, however, depletion of GOLPH3 alone or depolymerization of F-actin in WASp-sufficient T(H) cell

184 s to behavioral dysfunction, indicating that depolymerization of F-actin is causal and not consequent

185 By exploiting the fact that depolymerization of F-actin unleashes SVs focused at the

186 A role in depolymerization of highly substituted chemically comple

187 This finding is consistent with depolymerization of initially high-tension actin stress

188 Investigation on the RCM depolymerization of linear PCP reveals a more random cha

189 Depolymerization of microfilaments and microtubules, and

190 abilized moesin and directional memory while depolymerization of microtubules (MTs) disoriented moesi

191 ntly on micropatterned strips, we found that depolymerization of microtubules caused cells to change

192 Conversely, depolymerization of microtubules drastically alters the

193 The injury induces a fast spike of calcium, depolymerization of microtubules near the injury site, a

194 Arp2/3 complex, and it was not altered upon depolymerization of microtubules or inhibition of N-WASP

195 nism for metazoan kinetochores to couple the depolymerization of microtubules to power the movement o

196 Depolymerization of microtubules, deletion of the KIF5 m

197 Our results show that MCAK-mediated depolymerization of MTs is specifically targeted to the

198 erstand the mechanisms of polymerization and depolymerization of muscle myosins.

199 MICAL-2 induces redox-dependent depolymerization of nuclear actin, which decreases nucle

200 of poly(aryl ether sulfone)s (PSUs) from the depolymerization of PCs and in situ polycondensation wit

201 Ripening events are accompanied by gradual depolymerization of pectic polysaccharides, including ho

202 ermediate phases of papaya ripening, partial depolymerization of pectin to small size with decreased

203 Microbial depolymerization of plant cell walls contributes to glob

204 e by stimuli-induced head-to-tail continuous depolymerization of poly(benzyl ether) macro-cross-linke

205 Depolymerization of poly(tert-butyl 3,4-dihydroxybutanoa

206 lso known as lytic PMOs (LPMOs), enhance the depolymerization of recalcitrant polysaccharides by hydr

207 Depolymerization of sheaths and subsequent MS/MS analyse

208 The direct depolymerization of SiO2 to distillable alkoxysilanes ha

209 We report herein the base-catalyzed depolymerization of SiO2 with diols to form distillable

210 APTA-based calcium chelators cause immediate depolymerization of spindle microtubules in meiosis I an

211 groups caused a partial disorganization and depolymerization of starch granules.

212 b with loss of alpha-smooth muscle actin and depolymerization of stress fibers, and reduces the expre

213 filamentous actin (F-actin) and we observed depolymerization of synaptosomal F-actin accompanied by

214 strates to the flexible polymers invokes the depolymerization of the aggregates.

215 er several years of (*)OH exposure, involves depolymerization of the CD structure, characterized by v

216 ics do not depend on the cytoskeleton, acute depolymerization of the cytoskeleton removed ROP from th

217 Relocation upon depolymerization of the dynamic filaments suggests the p

218 ed lignin under acidic conditions results in depolymerization of the material into characterized arom

219 In all cases, ring closing metathesis (RCM) depolymerization of the PCP BB backbone appears to occur

220 olymer film surfaces by soil microorganisms, depolymerization of the polymer films by extracellular m

221 We found that depolymerization of the transient polymer, cyclic poly(p

222 this outward sliding of ipMTs is balanced by depolymerization of their minus ends at the poles, produ

223 ule dynamics involves the polymerization and depolymerization of tubulin dimers and is an essential a

224 f cells in G2/M phase (mitotic blockade) and depolymerization of tubulin in MCF-7 cells.

225 rotubule ends during both polymerization and depolymerization of tubulin.

226 r weight heparins (LMWH) prepared by partial depolymerization of unfractionated heparin are used glob

227 d that these changes result from substantial depolymerization of unphosphorylated NM2 filaments to mo

228 high-value alpha,beta-unsaturated esters to depolymerization of unsaturated polymers.

229 located in genetic loci that orchestrate the depolymerization of yeast alpha-mannans, it is likely th

230 new analytical strategies combining chemical depolymerization, oligosaccharide sequencing, and monosa

231 This selective effect of depolymerization on METH-associated memory was immediate

232 ffect of latrunculin-B (Lat-B)-induced actin depolymerization on outflow physiology in live mice.

233 in the dimer pool may be a consequence of MT depolymerization or breakdown.

234 dent, and lasting disruption by direct actin depolymerization or by inhibiting the actin driver nonmu

235 nvaginations (PNEIs), similar to microtubule depolymerization or down-regulation of the dynein cofact

236 increased flux can result in rapid filament depolymerization or maintenance of short filaments.

237 stants for degradation suggest that the main depolymerization pathway in the cell is by monomer remov

238 ment of dynein to the actin cortex, as actin depolymerization phenocopies dynein depletion, and direc

239 biochemical routes combining lignin chemical depolymerization, plant metabolic engineering, and synth

240 HSP70 transgene/speckle association by actin depolymerization prevented significant heat shock-induce

241 The effect of the depolymerization procedure was more pronounced for the r

242 g oligosaccharides obtained by synthetic and depolymerization procedures.

243 sis, which indicates that the polymerization-depolymerization process is reversible.

244 from an organosolv lignin through a two-step depolymerization process.

245 Exopolysaccharide-depolymerization products (EDP) varying in molecular wei

246 ization, whereas GPCR/cAMP signals and actin depolymerization promote Ski protein stability.

247 for initiation of myelination whereas actin depolymerization promotes myelin wrapping.

248 nversal FRAP experiments show that the actin depolymerization promotes the dissociation of V1-V0domai

249 y by controlling the activation of the actin depolymerization protein cofilin in the olfactory system

250 Continuous head-to-tail depolymerization provides faster rates of response than

251 employ a DyP-based system and ROS for lignin depolymerization, providing insights into the mechanism

252 dress this challenge and studied how the POM depolymerization rate and its uptake efficiency (2 main

253 Significant acceleration in cPPA depolymerization rate is triggered by the combination of

254 The response is a signal-induced depolymerization reaction that is continuous and complet

255 Actin depolymerization reagent latrunculin-B (Lat-B) abolished

256 Both glucose stimulation and F-actin depolymerization recruit a fraction of nearly immobile y

257 In myocardial tissue, we found microtubule depolymerization reduced myocardial viscoelasticity, wit

258 brication process proceeds through a partial depolymerization/repolymerization mechanism, providing m

259 PMS contains short actin filaments that are depolymerization resistant and sensitive to spectrin, ad

260 abnormal satellites, as complete microtubule depolymerization results in the disappearance of these a

261 ecreted enzymes that initiate lignocellulose depolymerization serve a crucial step in the bioconversi

262 on a single motor to achieve the microtubule depolymerization speed of a motor ensemble.

263 ability to switch between polymerization and depolymerization states, is crucial for their function.

264 that were not otherwise accessible without a depolymerization step.

265 s level of detail can fully optimized lignin depolymerization strategies be developed.

266 of new dimeric products in subsequent lignin depolymerization studies.

267 hibited GEF-H1 is localized to MTs, while MT depolymerization subadjacent to the cell cortex promotes

268 tand the mechanism by which INF2 accelerates depolymerization subsequent to severing.

269 sults offer insights into the two-enzyme PET depolymerization system and will inform future efforts i

270 crotubule-end structure that promotes sudden depolymerization, termed catastrophe [1-4].

271 aced the waves of tubulin polymerization and depolymerization that occur at mitotic entry and exit in

272 to accelerate both actin polymerization and depolymerization, the latter requiring filament severing

273 t MAPKAP2-mediated HSP27 phosphorylation and depolymerization, thereby blocking HSP27-regulated survi

274 conformational change to couple microtubule depolymerization to chromosome movement.

275 substituted with ferulic acid, thus limiting depolymerization to fermentable sugars.

276 How microtubules transition from depolymerization to polymerization, known as rescue, is

277 is of large polymers (630 kDa) and catalytic depolymerization to recycle monomers.

278 domain provides a potential target for mucin depolymerization to remove mucus plugs in COPD and other

279 laldehyde), undergoes mechanically initiated depolymerization to revert the material to monomers.

280 to be dynamic in solution enabling selective depolymerization under dilute conditions, which can be t

281 We previously demonstrated that actin depolymerization under force is governed by catch-slip b

282 creased rapidly and stimulated their gradual depolymerization (unlike their rapid degradation during

283 ubule lattice: GTP-bound, which is stable to depolymerization; unstable GDP-bound; and stable Taxol a

284 Efficient depolymerization upon irradiation at 254 nm was confirme

285 d ability of lysine mutants to mediate actin depolymerization via filament disassembly although not s

286 each 0.51+/-0.10 MPa, whereas signal-induced depolymerization via quinone methide intermediates reduc

287 ed from alginate, by alginate lyase-mediated depolymerization, were structurally characterized by mas

288 increased by both sodium blockade and actin depolymerization, whereas increased actin polymerization

289 at TNFalpha induces geometry-dependent actin depolymerization, which enhances IkappaB degradation, p6

290 d that Aip1 regulates cofilin-mediated actin depolymerization, which is required for normal neutrophi

291 misaligned chromosomes, reduced microtubule depolymerization, which led to significant pro-M I/M Iar

292 AMPK induces actin depolymerization, which reduces vascular tone and the re

293 polymers to provide amplified responses via depolymerization while simultaneously enhancing the rate

294 ntration in the midgut drives lignocellulose depolymerization, while a thicker gut wall in the anteri

295 nel closing switch operated by calsequestrin depolymerization will limit depletion, thereby preventin

296 For comparing the results obtained by depolymerization with classical methods for polymer anal

297 dihydrofuran) can be recycled to monomer via depolymerization with Grubbs catalyst or degraded to sma

298 They can also be recycled by depolymerization with specific solvents able to displace

299 We further show MT depolymerization within biofilms is regulated by the Srb

300 migrating dendritic cells, local microtubule depolymerization within protrusions remote from the micr