ライフサイエンスコーパス: depressing

1 strong synaptic connections were exclusively depressing.

2 ence are not found when the synapses are non-depressing.

3 roduced at least a 3-second-long interval by depressing a lever for reward.

4 sensitive than alpha1(-/H) mice to the motor-depressing action of diazepam, but each of these conditi

5 in were obtained from their effect on the Tm-depressing activities of these proteins.

6 ophic plankton community exceeds the supply, depressing ambient concentrations.

7 In addition, depressing amplification using energy deprivation recapi

8 limate change will generate sizable activity-depressing and activity-delaying effects in summer when

9 fferential recruitment of AMPA and NMDARs at depressing and facilitating synapses in layers 2/3 of th

10 The effect of CCh on both depressing and facilitating synapses was blocked by the

11 s synapses onto parvalbumin interneurons are depressing and have a high release probability.

12 Depressing and sensitizing forms of adaptation also occu

13 that human synaptic connections were purely depressing and that they recovered three to four times m

14 but not within the same class, were markedly depressing and were more powerful to sculpt activity of

15 ed the nucleic acid helix-destabilizing t(m)-depressing) and binding activities of HIV-1 NCp7 protein

16 d with LS neurons, ES neurons had strong and depressing autapses, which enhanced spike-timing precisi

17 denoson rapidly terminated sustained PSVT by depressing AV nodal conduction without causing hypotensi

18 me by increasing the bone formation rate and depressing bone resorption.

19 I metabotropic glutamate receptors (mGluRs), depressing both glutamate and GABA release to modulate b

20 s that provide opioid-like analgesia without depressing breathing.

21 e cells, by activating GIRK conductances and depressing calcium currents.

22 independent regulators for potentiating and depressing central synapses.

23 ic constrictor (PY) neuron has an inhibitory depressing chemical and an electrical component.

24 tic, identity: FS interneurons made strongly depressing connections on FS, SOM, and RS targets, while

25 asing thin-filament stiffness and ultimately depressing contractile force and relaxation rate.

26 phorylation of cTnI plays a dominant role in depressing contractility and exerts an antithetic role o

27 d to increase dynamic wave stability without depressing contractility, which may have promise as an a

28 equivalent anti-fibrillatory effects without depressing contractility.

29 gy designed to abbreviate excitation without depressing contraction.

30 lasticity, which varies from facilitating to depressing depending on the particular system.

31 in cTnI C terminus impacts heart function by depressing diastolic function at baseline and limiting s

32 This activity-depressing effect is larger than previous daily or month

33 The depressing effect of such bridging ligand modification o

34 ntagonist eticlopride (0.2 mg/kg) had a weak depressing effect on basal activity and was completely i

35 ng by riparian vegetation also had a greater depressing effect on biomass in later seasons, probably

36 Two regimens had a significant depressing effect on the microbiome after 2 weeks of tre

37 Nifedipine had a depressing effect.

38 peptide contents similarly demonstrated the depressing effects of melittin on membrane bending modul

39 Why is social bias and its depressing effects on low-status or low-performing group

40 ossibility suggested by the types of fitness-depressing effects that TEs are believed to have.

41 dings in vitro showed that Ivy cells receive depressing EPSPs from pyramidal cells, which in turn rec

42 (evoked postsynaptic spikes) to weak (small depressing EPSPs).

43 lls and received the briefest, most strongly depressing EPSPs, while bitufted interneurones with broa

44 s early as 5 DIV, reducing SCO amplitude and depressing ESA and burst frequencies by 60-70%.

45 nucleus to edge TRN cells evoke slower, less depressing excitatory currents that drive more persisten

46 Our results establish that neurons receiving depressing excitatory inputs can act as powerful multipl

47 st, LS decreased the E/I balance by strongly depressing excitatory transmission, and the homeostatic

48 n by allowing synaptic insertion of NR2A and depressing expression of NR2B subunits.

49 ptotic factors BAX, BAD, p73, and PUMA while depressing expression of the antiapoptotic genes MCL1, X

50 ntiation at the cortico-amygdala synapses by depressing feed-forward GABAergic inhibition of principa

51 pressing (PV+) basket cells while indirectly depressing GABA release from CCK expressing (CCK+) baske

52 depressed glutamate signaling, while mildly depressing GABA transmission.

53 s opioids did not enhance mossy fiber LTP by depressing GABAA inhibition.

54 oups stabilize the surface of Li(2)MnO(3) by depressing gas release and side reactions with the elect

55 enome editing confirmed its functionality in depressing GATA6 expression and the efficiency of pancre

56 ppear to suppress cocaine seeking in part by depressing glutamatergic receptor activation in the same

57 Ranolazine treats angina without depressing hemodynamic status.

58 es, allowing polyclonal viruses to bloom and depressing host fitness.

59 logical functions that impact health through depressing inflammation.

60 The LP neuron, in turn, makes a depressing inhibitory synapse to the PD neurons, providi

61 found that combinations of facilitating and depressing inputs enabled firing of MOC neurons over a s

62 ry information from entorhinal cortex whilst depressing inputs from previously encoded representation

63 In contrast, depressing inputs onto 10/10 neocortical pyramids and fa

64 Depressing inputs onto some interneurones, such as CA1 b

65 pression that a problem is intractable, thus depressing interest in future attempts.

66 2 planes into the superconductor, eventually depressing its critical temperature.

67 shock (TS) mimics the effect of 5-HT by both depressing L29 synaptic transmission and by reducing L29

68 ene impairs lysosomal acidification, thereby depressing lysosomal hydrolytic activities and turnover

69 d result in the dehydration of airway mucus, depressing MC.

70 ther provide a bridge between the metastasis-depressing miRNA and the key genes that govern the malig

71 ons but remain attached to the basal lamina, depressing more central neighbours to "telescope" the ep

72 imates of the rates and effects of viability-depressing mutations in two sets of lines with accumulat

73 e that in Drosophila melanogaster, viability-depressing mutations occur at the surprisingly high rate

74 urane decrease force development by directly depressing myofilament Ca(2+) responsiveness and have bi

75 ion of Kv1.2 in the plasma membrane, thereby depressing NAcSh MSNs firing.

76 not appear to act through a 5-HT receptor in depressing neuronal function in the invertebrates (crayf

77 and decrease of PBL height, and thus further depressing of aerosol and water vapour in a very shallow

78 Finally, depressing OFC-DMS pathway with a high frequency stimula

79 rted facilitating bipolar cell synapses into depressing ones.

80 Widely heralded for depressing ongoing immune responses, renewed interest in

81 est that regional haze in China is currently depressing optimal yields of approximately 70% of the cr

82 e Purkinje cells, evoking complex spikes and depressing parallel fibre synapses.

83 luence comprises a facilitatory centre and a depressing peripheral zone, which together shape the inf

84 ay retain their antiinflammatory efficacy by depressing PGE(2), while avoiding the adverse cardiovasc

85 In vivo, depressing PKG activity lowers CHIP-S20 phosphorylation

86 erbivores could trigger local extinctions by depressing plant population growth.

87 op continue to exhibit both facilitating and depressing polysynaptic IPSCs, indicating that this robu

88 ultural pests, it has been less effective in depressing populations of Ae. aegypti This limitation is

89 activation during HFS generates MF-SLIN LTD, depressing presynaptic release through a PKC-dependent m

90 ssets and compete vigorously with producers, depressing prices and production.

91 e of these major MRSA clones, highlighting a depressing progression of increasing drug resistance wit

92 diol can induce cellular proliferation while depressing protein production in cultures of human, prem

93 cruitment and ensuing lung injury by greatly depressing pulmonary production of TNF alpha.

94 l energy production via glucose oxidation by depressing pyruvate dehydrogenase complex activity.

95 nge factor-from the plasma membrane, thereby depressing Rac activity and abolishing the constitutive

96 In contrast, depressing Rap1 activity by expressing Rap1GAP led to di

97 hat the trigeminal loop implements a rapidly depressing reflex that provides positive sensory feedbac

98 By favoring release from bursts while depressing release from tonic signals, nicotine spreads

99 on of the central nucleus of the IC evoked a depressing response in the MGB with no metabotropic glut

100 ganization of the systolic Ca2+ transient of depressing RyR open probability (P(o)) with tetracaine o

101 Depressing RyR P(o) increased the variability of the Ca2

102 The mutation induces Ca(2+) imbalance by depressing RyR2 channel activity during excitation-contr

103 ssessment of vitamin A status by transiently depressing serum retinol concentrations.

104 hange (NCX) function have been implicated in depressing SR Ca2+ content and contractile function in h

105 rvival through multiple mechanisms including depressing stroke volume, increasing fluid loss into the

106 urrent clamp experiments revealed that blood depressing substance (BDS) and intracellular dialysis of

107 um) and block by the peptide inhibitor blood depressing substance I (BDS-I).

108 l spinal neurons, blockade of Kv3.4 by blood depressing substance II suppresses axon growth via an in

109 ha-dendrotoxin at nanomolar levels, or blood-depressing substance-I at nanomolar levels.

110 osol mass, and can influence CCN activity by depressing surface tension, contributing solute, and inf

111 When the maximal conductance of the depressing synapse is small, the oscillation period is d

112 ron that receives feedback inhibition from a depressing synapse.

113 termined by the strength and dynamics of the depressing synapse.

114 all change in the maximal conductance of the depressing synapse.

115 depending on the maximal conductance of the depressing synapse.

116 s, a fact that we linked to the inclusion of depressing synapses in our model.

117 tiating synapses onto excitatory neurons and depressing synapses onto inhibitory neurons.

118 cles, while phasic motoneurons form stronger depressing synapses onto multiple muscles.

119 ws of limited information transfer in rodent depressing synapses, fast recovering synapses of human n

120 uron nerve terminal, as are facilitating and depressing synapses.

121 litation would be present at these and other depressing synapses.

122 opulations are in receipt of facilitating or depressing synapses.

123 modating pyramidal cells interconnected with depressing synapses.

124 at first, seem inconsistent with input from depressing synapses.

125 q, we find that PVALB neurons typically show depressing synaptic characteristics, whereas other inter

126 act of transient parallel fiber input, while depressing synaptic gain for sustained parallel fiber in

127 eptors associated with nerve fibers, thereby depressing taste responses.

128 eurotrophins regulate filopodial dynamics by depressing the activation of RhoA that occurs through p7

129 oxygen species (ROSs) levels by about 38%and depressing the caspase-3 activity by about 63%.

130 that mutant phospholamban was not capable of depressing the enhanced relaxation parameters of the pho

131 ctively disrupts the H-bond network, thereby depressing the freezing point while maintaining high ion

132 that NK3R activation excited BLA neurons by depressing the G protein-activated inwardly rectifying K

133 Furthermore, the effect of low R:FR depressing the JA response was conserved in mutants impa

134 Mucosal reflexes were elicited by lightly depressing the mucosa with a sponge.

135 ic stimulus frequencies (> 30 Hz; p < 0.01), depressing the overall force-frequency relationship (p <

136 and increased N2 O flux, while significantly depressing the Q10 for CO2 , and having no effect on the

137 ein diversity is an important contributor to depressing the serum freezing point.

138 TEA inhibited nicotinic receptor currents by depressing the single-channel amplitude.

139 s little prospect of killing trypanosomes by depressing their glycolysis to a level incapable of sust

140 phylogenetic scale are routinely capable of depressing their metabolic rate to 5-15% of that at rest

141 ction in a dose-dependent fashion (maximally depressing to 16.2 + 1.9% baseline developed force for T

142 a profound developmental shift of iSTP from depressing to facilitating after the onset of hearing.