ライフサイエンスコーパス: deprivation

1 tion index (range 0-1, higher indicates more deprivation).

2 and loss of dendritic spines following sleep deprivation.

3 ependent PDAC cells during Ser/Gly (glycine) deprivation.

4 sporters, occurs in the cht7 mutant during N deprivation.

5 depending on the age and the mode of sensory deprivation.

6 ncreased sensitivity of the cells to glucose deprivation.

7 with progressive neighborhood socioeconomic deprivation.

8 ial for cell survival during chronic glucose deprivation.

9 a proper and complete adaptation to nutrient deprivation.

10 independent of a postcode-derived measure of deprivation.

11 ice that underwent early long-term monocular deprivation.

12 ase II occupancy in cells undergoing glucose deprivation.

13 tion to increased sleep need following sleep deprivation.

14 es impairs the homeostatic response to sleep deprivation.

15 lytic proteins in cells responding to oxygen deprivation.

16 or this interaction increases during glucose deprivation.

17 expression of the sll0944 gene upon nitrogen deprivation.

18 resulting in delayed recovery from nutrient deprivation.

19 Harvested fruit undergo carbon and energy deprivation.

20 segments on apical dendrites following sleep deprivation.

21 ed using the 2011 Scottish Index of Multiple Deprivation.

22 not appear to change in response to sensory deprivation.

23 equired for increased sensitivity to glucose deprivation.

24 Nearly 70% of women lived in areas of social deprivation.

25 taphosphate (pppGpp) in response to nutrient deprivation.

26 ed in acute and chronic mouse models of zinc deprivation.

27 imurium in host tissues by causing magnesium deprivation.

28 I: 2.68, 11.98), homelessness and area-level deprivation.

29 antly reduced after total sleep or REM sleep deprivation.

30 cle progression during conditions of glucose deprivation.

31 y, during hospital bedrest, and during sleep deprivation.

32 dendritic arborization after oxygen-glucose deprivation.

33 OR, by induction of ER stress, or by glucose deprivation.

34 rvival and energy homeostasis under nutrient deprivation.

35 fically regulates odr-10 in response to food deprivation.

36 ostatic regulation of sleep need after sleep deprivation.

37 in, and is a source of energy during glucose deprivation.

38 n D levels, independent of other measures of deprivation.

39 gion, but not mimicry, was affected by sleep deprivation.

40 r replication, and cell division following N deprivation.

41 t mice remained sensitive to brief monocular deprivation.

42 ensor that reprograms metabolism upon carbon deprivation.

43 nic acid, correlating with signs of nitrogen deprivation.

44 ward processing hub sensitive to acute sleep deprivation.

45 emble mean FR induced by prolonged monocular deprivation.

46 scue deficits induced by prolonged monocular deprivation.

47 visual attention defects brought on by sleep deprivation.

48 rd ratio 1.38, 95% CI 1.27-1.51), persistent deprivation (1.77, 1.62-1.93), or loss or threat of loss

49 22-89] and median Scottish Index of Multiple Deprivation 2012 decile of 8 [IQR 6-10]), mean systolic

50 Participants underwent partial sleep deprivation (3 h sleep opportunity at the end of night),

51 mation; sRT; timing and duration of androgen deprivation; 3-y PSA results; and clinical events were d

52 Upon serum deprivation, a subset of AEs pre-marked by the activity-

53 cerebrospinal fluid (CSF) and chronic sleep deprivation accelerates the spread of tau protein aggreg

54 ales exhibit high odr-10 expression and food deprivation activates odr-10 in adult males [4-6].

55 y to have high MLVI even after adjusting for deprivation (adjusted odds ratio 4.0 95% confidence inte

56 processing, but it is unclear whether sleep deprivation affects emotional mimicry and contagion.

57 B(12) deprivation also caused a substantial increase in reacti

58 Total sleep or REM sleep deprivation also prevented MD- and FC-induced reduction

59 ectrophysiology, we measured how acute sleep deprivation alters transmission at BLAp-NAc synapses in

60 eria: Loss to follow-up, managed surgically, deprivation amblyopia.

61 of ER-mutant tumor cells to survive estrogen deprivation, anchorage independence, and invasion.

62 Areas with less socioeconomic deprivation and a higher concentration of white resident

63 ociations between neighborhood socioeconomic deprivation and an objective surrogate measure of medica

64 lained by its compromised viability during N deprivation and by the occurrence of abortive divisions

65 cascade of changes induced by acute nicotine deprivation and call for further investigation into the

66 ), which has been partly attributed to sleep deprivation and circadian misalignment [1-6].

67 gations have focused on the effects of sleep deprivation and circadian time, little is known about ho

68 en we added adjustment for index of multiple deprivation and ethnicity, and then for a broad range of

69 These findings link glucose deprivation and H2A ubiquitination to regulation of the

70 AMPK activity is increased by nutrient deprivation and inhibited by overnutrition, inflammation

71 the study of chrono-medical timing of sleep deprivation and light exposure for their positive effect

72 against negative effects of in-person social deprivation and other pandemic-related stress.

73 The review shows that experienced group deprivation and perceived immorality are among the core

74 l associations of neighborhood socioeconomic deprivation and racial segregation on organ donor regist

75 Vigilant attention is impaired by sleep deprivation and restored after rest breaks and (more end

76 ) and 4.62 (95% CI 2.12-10.08) (adjusted for deprivation and self-reported hypertension, heart diseas

77 ations of these with melanoma in addition to deprivation and socio-economic stressors.

78 o the metabolism of IVD cells under nutrient deprivation and the information for developing treatment

79 x (range [0, 1]; higher values indicate more deprivation) and a racial index of concentration at the

80 g for sociodemographic (sex, age, ethnicity, deprivation) and maternity (maternal age, maternal smoki

81 hat RUNX1(+) PLCs are unaffected by androgen deprivation, and do not contribute to the regeneration o

82 nd by patient characteristics, socioeconomic deprivation, and duration of admission.

83 R, CHI3L1, and ISG, arise following estrogen-deprivation, and ER-mutant metastases may respond to imm

84 -related gene expression during nitrogen (N) deprivation, and its predicted protein interaction domai

85 als, inadequate amino acid supplies, glucose deprivation, and lactic acidosis, all of which pose chal

86 isk factors such as ethnicity, socioeconomic deprivation, and obesity, but provide a starting point f

87 Surprisingly, these responses to food deprivation are not triggered by internal metabolic cues

88 experimental manipulations, including visual deprivation, are able to induce critical period-like pla

89 Furthermore, glutamine deprivation, as well as the antimetabolic drugs 2-deoxyg

90 ikely be poorly adapted to coping with B(12) deprivation, association with B(12)-producers can ensure

91 Deprivation Index characterized neighborhood deprivation at the census tract level.

92 ing non-rapid eye movement sleep after sleep deprivation at the network and single-cell level.

93 synthesis and DNA synthesis, with amino acid deprivation augmenting cisplatin's effects.

94 The three vortex stresses of (a) nutritional deprivation, (b) thermal stress and (c) genetic bottlene

95 lmark of prostate cancer (PCa) with androgen deprivation being standard therapy.

96 djusted for the following major confounders: deprivation, birthweight, maternal age, sex, and multipl

97 cy, adjusting for ethnicity, working status, deprivation, body mass index, and sedentary time.

98 idence interval 1.53-1.65)); greater age and deprivation (both with a strong gradient); diabetes; sev

99 ROS are not just correlates of sleep deprivation but drivers of death: their neutralization p

100 t MiDAS does occur at FRAXA following folate deprivation but proceeds via a pathway that shows some m

101 Cells react to nutrient deprivation by adapting their metabolism, or, if starvat

102 Cells adjust to nutrient deprivation by reversible translational shutdown.

103 Rationale: Sleep deprivation can alter endurance of skeletal muscles, but

104 a coli encountering cell stress and nutrient deprivation can up-regulate and activate DinB/pol IV, th

105 Partial sleep deprivation caused decreased activation in fusiform gyri

106 In the face of perceived nutrient and oxygen deprivation, cells activate low-energy sensors, which in

107 plitude was significantly lower in the sleep-deprivation condition (4.5 muV [IQR, 2.5-6.4] vs. 7.3 mu

108 In the sleep-deprivation condition, preinspiratory motor potential am

109 Interestingly, in Leu deprivation conditions, the dominant effects on autophag

110 procal connectivity of S1BC after unilateral deprivation consistent with the model that interhemisphe

111 Deprivation curiosity (the tendency to seek information

112 Deprivation did not disrupt the degree of speed tuning,

113 Folate deprivation drives the instability of a group of rare fr

114 NS, which is particularly vulnerable to O(2) deprivation due to high energetic demand.

115 surface area were positively associated with deprivation duration.

116 cal direction selectivity produced by motion deprivation during development.

117 However, postmenopausal estrogen deprivation during midlife and older age has a detriment

118 We also found that iron deprivation during T cell stimulation negatively impacts

119 Amino acid deprivation enhanced cisplatin's cytotoxicity, increasin

120 but risk remained high, after adjustment for deprivation, ethnicity, smoking and obesity: adjusted HR

121 deprives it of detailed spatial vision (form deprivation, FD).

122 e the standard agents for achieving androgen deprivation for prostate cancer despite the initial test

123 two nights of recovery sleep following sleep deprivation fully restores brain and cognitive function.

124 In response to nutrient deprivation, Gcn2 phosphorylates eIF2alpha, thereby repr

125 th initiation and intensification: age, sex, deprivation, glycated haemoglobin (HbA1c), body mass ind

126 e to irregular light-dark patterns and sleep deprivation has been associated with beta amyloid peptid

127 rajectory, those who had early-life material deprivation (hazard ratio 1.38, 95% CI 1.27-1.51), persi

128 In response to severe water deprivation, however, both seed yield and weight were re

129 TyrRII levels rise following sleep deprivation in a Ca(2+)-dependent manner, promoting furt

130 suppress CDCP1 expression and that androgen deprivation in combination with loss of PTEN promotes th

131 from young adults who were exposed to severe deprivation in early childhood in the Romanian orphanage

132 compelling evidence that time-limited severe deprivation in the first years of life is related to alt

133 s, and neutrophils, suggesting that nutrient deprivation in the tumor environment can serve as an ini

134 vival to oxidative stress following nutrient deprivation in three prostate cancer models displaying v

135 g antibodies re-sensitizes tumors to hormone deprivation in vitro and in vivo.

136 prevented apoptosis in response to nutrient deprivation in vitro and promoted tumor aggression, chem

137 Tumour cells adapt to nutrient deprivation in vivo, yet strategies targeting the nutrie

138 Acute sleep deprivation increased sucrose self-administration in mic

139 dings from our group reveal that acute sleep deprivation increases levels of tau in mouse brain inter

140 5% increase in MLVI for each 0.1 increase in deprivation index (95% confidence interval, -1% to 11%;

141 : 1.60, 2.16), and neighborhoods with a high deprivation index (fourth quartile vs. first: OR = 1.14,

142 addresses, was a neighborhood socioeconomic deprivation index (range 0-1, higher indicates more depr

143 ciation between a neighborhood socioeconomic deprivation index (range [0, 1]; higher values indicate

144 Quartiles of the Social Deprivation Index characterized neighborhood deprivation

145 The area deprivation index is a publicly available composite scor

146 which was significantly larger than the area deprivation index of patients not readmitted (51.8 [+/-

147 The mean area deprivation index of patients who were readmitted was 62

148 Black and White patients within each Social Deprivation Index quartile, adjusted for geographic clus

149 (95% CI, 4.1%-9.5%; P<0.0001) across Social Deprivation Index quartiles.

150 d logistic regression models, a greater area deprivation index was significantly associated with read

151 e associations between readmissions and area deprivation index were explored using logistic regressio

152 I), smoking status, alcohol intake, Townsend deprivation index, education level, diabetes status, sph

153 orhood disadvantage scores, such as the area deprivation index, may help to better understand how con

154 s tract level, with each 0.1 decrease in the deprivation index, the organ donor registration rate inc

155 additional adjustment for patient-level area deprivation index.

156 geocoded and linked to their respective area deprivation index.

157 obesity (DIO) and refeeding, whilst nutrient deprivation induced lncRNAs in mouse liver.

158 e study protein sequestration during glucose deprivation-induced ATP decline in Saccharomyces cerevis

159 sought to identify the mechanisms in glucose deprivation-induced cancer cell death and then designed

160 ling, we found that cells undergoing glucose deprivation-induced cell death exhibited dramatic accumu

161 ng on this observation, we show that glucose deprivation-induced cell death is driven not by the lack

162 gned inhibitor combinations to mimic glucose deprivation-induced cell death.

163 Slug is required in PDAC cells for glutamine deprivation-induced EMT, cell motility, and nutrient str

164 sustained MET signaling eliminates monocular deprivation-induced ocular dominance plasticity during t

165 N deprivation-induced quiescence was accompanied by a stro

166 Neighborhood socioeconomic deprivation is associated with adverse health outcomes.

167 Early childhood deprivation is associated with higher rates of neurodeve

168 In addition, a brief period of junk-food deprivation is needed for the synaptic insertion of CP-A

169 Sleep deprivation is proposed to inhibit top-down-control in e

170 Androgen deprivation is the cornerstone of prostate cancer treatm

171 A lack of basic resources within a society (deprivation) is associated with increased cancer mortali

172 o rewire and recover from injury and sensory deprivation, it can lead to tinnitus as an unwanted side

173 nimals and plants to acutely adapt to oxygen deprivation, its functional and historical roots in hypo

174 re we show, using flies and mice, that sleep deprivation leads to accumulation of reactive oxygen spe

175 how that nutrient stress caused by glutamine deprivation leads to the induction of epithelial-mesench

176 childhood adversities: poverty and material deprivation, loss or threat of loss within the family, a

177 Long-term estrogen deprivation (LTED) with tamoxifen (TAM) or aromatase inh

178 Areas of chronic deprivation may indicate within-country poverty traps an

179 aracterize the effects of juvenile monocular deprivation (MD) on the responses of neurons in V1 and t

180 lar dominance plasticity following monocular deprivation (MD).

181 types of stress including hypoxia, nutrient deprivation, metabolic, and oxidative stress.

182 e against a combination of abiotic (nutrient deprivation, metal toxicity) and biotic (pathogens, herb

183 Furthermore, after sleep deprivation, mice with lesioned VTA(Vgat) neurons did no

184 Following chronic sensory deprivation, microglia undergo a morphological transitio

185 preventable circadian misalignment and sleep deprivation might underlie MVA risk increases.

186 high expression of m1 and m3 under androgen deprivation mimicking castration and androgen receptor i

187 0.61-0.30]; P = 1.1x10(-8)), greater social deprivation (most significant for GCIPL: -0.28 mum for m

188 Across deprivation sessions, we found that deprivation narrows and focuses the brain's motivational

189 Upon food deprivation, odr-10 is directly activated by DAF-16/FoxO

190 o acid deprivation suggest that intermittent deprivation of an essential amino acid could allow dose

191 Deprivation of glutamine by glutamine-withdrawal, GLS kn

192 DNA strand breaks in vitro, and intermittent deprivation of lysine combined with a sub-therapeutic do

193 Our analyses demonstrate that B(12) deprivation of metE7 disrupts C1 metabolism, causes an a

194 s ATP production, it remains unclear whether deprivation of mitochondrial TCA substrates alters mitoc

195 cadian-like cycles in primary mouse neurons, deprivation of oxygen and glucose triggered a smaller re

196 ctivity of plasmablasts resulted in nutrient deprivation of the germinal center reaction, limiting th

197 polysaccharide (LPS), KCl and oxygen/glucose deprivation (OGD) that reflect inflammation, depolarizat

198 primary rat neurons following oxygen-glucose deprivation (OGD).

199 imed to investigate effects of partial sleep deprivation on emotional contagion and mimicry in young

200 Effects of arginine deprivation on osteoclastogenesis are independent of mTO

201 crucial to understanding the impact of sleep deprivation on performance in safety-critical tasks, is

202 ives: We aimed to assess the effect of sleep deprivation on respiratory motor output and inspiratory

203 Recent studies on the effects of sleep deprivation on synaptic plasticity have yielded discrepa

204 The impact of childhood deprivation on the adult brain and the extent to which s

205 ase, and increased apoptosis following serum deprivation or chemotherapy.

206 However, when challenged by food deprivation or harsh environmental conditions, many mamm

207 independently associated with socioeconomic deprivation (OR, 5.39; 95% CI, 1.46-19.89; P = 0.01).

208 ety of stress conditions, including nutrient deprivation, oxidative stress, and pathogen infection.

209 Here we use a noninvasive and reversible deprivation paradigm and converging neural and behaviora

210 evant factors, including ACEs, socioeconomic deprivation, parental substance use, and mental health.

211 m, which triggers the activation of nutrient deprivation pathways to promote cellular homeostasis.

212 ffectively enhanced the efficacy of arginine deprivation (pegylated arginine deiminase) and chemother

213 model of CSR where mice underwent 18-h sleep deprivation per day for 5 consecutive days, we performed

214 d alcohol consumption after repeated alcohol deprivation periods.

215 to RP alone or neoadjuvant CHT with androgen deprivation plus docetaxel (75 mg/m(2) body surface area

216 Instead, prolonged food deprivation potentiates temperature responses in the AWC

217 Our data suggests that nutrient deprivation primes prostate cancer cells for adaptabilit

218 , and the strongest evidence yet that visual deprivation produces bona fide cortical change.

219 es, new medications, sensory overload, sleep deprivation, prolonged bed rest, malnourishment, and sle

220 Nutrient deprivation promoted a tight coupling between glucose up

221 Our results demonstrate that glutamine deprivation promotes CAF migration and invasion, which i

222 interval [95% CI] 1.11-1.13, p < 0.001, per deprivation quintile increase).

223 Children were distributed across all deprivation quintiles (most to least deprived: 22.7%, 20

224 Deprivation quintiles were classified using the 2011 Sco

225 umference, waist-hip ratio, and neighborhood deprivation (|r(g)| ~ 0.1-0.3) and positive genetic corr

226 uli, such as amino acid starvation, nutrient deprivation, rapamycin, and lipopolysaccharide.

227 umans and other social species, early social deprivation reduced social preference in juvenile zebraf

228 d trends over time and differences by social deprivation, region, and ethnicity were examined using P

229 No deprivation-related effects were observed in limbic regi

230 The deprivation-related increase in right inferior temporal

231 Our findings suggest that socio-economic deprivation remains a driver of tuberculosis in England,

232 cellular glutamate to prevent the amino acid deprivation response and cell death.

233 actor PSR1, which is the major mediator of P deprivation responses in Chlamydomonas.

234 However, monocular deprivation results in adaptive myelin remodeling only i

235 st disadvantaged patients-defined by an area deprivation score in the highest 20% nationally-served a

236 Neither BMI nor the Townsend deprivation score were predictive in either survival ana

237 Using the Townsend deprivation score, the most deprived group did not have

238 rotonin and dopamine in the brain upon sleep deprivation (SD).

239 autophagy, protein trafficking, and glucose deprivation sensing.

240 Nutrient deprivation sensors are suppressed in states of perceive

241 These three nutrient deprivation sensors exert striking cardioprotective effe

242 Across deprivation sessions, we found that deprivation narrows

243 Therefore, promotion of ketogenic nutrient deprivation signaling by SGLT2 inhibitors may explain th

244 Sleep deprivation significantly impairs a range of cognitive a

245 n vitro Although glutamine, but not glucose, deprivation significantly reduced cell viability in MDV-

246 f autophagy in states of nutrient and oxygen deprivation-sirtuin-1 (SIRT1), AMP-activated protein kin

247 suffer from educational difficulties, social deprivation, socio-economic dysfunction, personality pro

248 Netrin1 deprivation stimulates MST1 activation and interaction w

249 By contrast, sleep deprivation studies using approaches avoiding novelty-in

250 chemical and cytotoxic effects by amino acid deprivation suggest that intermittent deprivation of an

251 h during synchronized growth and following N deprivation, suggesting the presence of low abundance su

252 lts in increased vulnerability to amino acid deprivation, susceptibility to retinal degeneration caus

253 8 h, and combining cisplatin and amino acid deprivation synergistically reduced intracellular PRPP.

254 ailure was significantly shorter after sleep deprivation than after normal sleep: (30 min [interquart

255 thaliana and the root microbiota under iron deprivation that is dependent on the secretion of plant-

256 ients will initially respond to the androgen deprivation, the disease often progresses to castrate-re

257 Following glucose deprivation, the import of l-cystine and its subsequent

258 se were all prescribed 24 months of androgen deprivation therapy (ADT) and had lymph node irradiation

259 ding the influence of sequencing of androgen deprivation therapy (ADT) and radiotherapy (RT) on outco

260 se-escalated radiotherapy (RT) with androgen-deprivation therapy (ADT) is a standard definitive treat

261 Radiotherapy in combination with androgen deprivation therapy (ADT) is a standard treatment option

262 Androgen deprivation therapy (ADT) is still a mainstay of treatme

263 ocrine prostate cancer (NEPC) after androgen-deprivation therapy (ADT) is well-known.

264 ed prostate cancer, the addition of androgen-deprivation therapy (ADT) or a brachytherapy boost (BT)

265 y androgens, and this suggests that androgen-deprivation therapy (ADT) would lead to hyperactivity of

266 transrectal US-guided biopsy, prior androgen deprivation therapy (ADT), and any prior CT results were

267 pic change of prostate cancer after androgen deprivation therapy (ADT), and it ultimately develops in

268 Intermittent androgen deprivation therapy (IADT) is an attractive treatment fo

269 rostatectomy (n = 402) or EBRT with androgen deprivation therapy (n = 217) for men with unfavorable-r

270 overall survival than placebo plus androgen-deprivation therapy among men with nonmetastatic, castra

271 y Gleason score, and prior therapy (androgen deprivation therapy and external-beam radiation therapy)

272 on therapy in 19.3% of patients and androgen-deprivation therapy in 7.4%.

273 metastatic disease (n = 103), after androgen deprivation therapy only (n = 16), after surgery and wit

274 at chemohormonal therapy (CHT) with androgen-deprivation therapy plus docetaxel before RP would impro

275 umors that have become resistant to androgen deprivation therapy represent the major challenge in tre

276 Enzalutamide plus androgen-deprivation therapy resulted in longer median overall su

277 erapy and lower rates of additional androgen deprivation therapy than those with extrafossa disease.

278 Patients on androgen deprivation therapy were excluded.

279 ths) who were continuing to receive androgen-deprivation therapy were randomly assigned (in a 2:1 rat

280 herapy (79.1% vs. 82.1%, P = 0.55), androgen deprivation therapy within the 6 mo preceding imaging (8

281 prostate cancer patients receiving androgen deprivation therapy, highlighting the evolutionary conse

282 inical trial of neoadjuvant intense androgen deprivation therapy.

283 sitized ASS1-abundant L3.3 cells to arginine deprivation therapy.

284 c antigen (PSA) levels while taking androgen-deprivation therapy.

285 tate cancer undergoing intermittent androgen deprivation therapy.

286 individual's chronotype and degree of sleep deprivation to answer these questions.

287 5, p < 0.001, compared to <35 years), social deprivation (Townsend score quintile 5/most deprived, aO

288 Food-deprivation transiently activates male odr-10 expression

289 effective to sensitize PC cells to arginine deprivation treatment and chemotherapy through targeting

290 f these 'unassigned' fish was higher in food deprivation treatments, but lower in warm treatments.

291 deficits following one night of total sleep deprivation (TSD) in 39 healthy adults in a controlled i

292 r rates of psychiatric illness, neighborhood deprivation, unemployment, social welfare, early retirem

293 fore, the antitumor effect associated to SHH deprivation, usually thought to be a consequence of the

294 t to determine if neighborhood socioeconomic deprivation was associated with adherence to immunosuppr

295 Socioeconomic deprivation was significantly associated with lower upta

296 Monitoring cells before and after zinc deprivation we found the position of cells within the ce

297 manian adoptees (with between 3 and 41 mo of deprivation) were compared with 21 nondeprived UK adopte

298 nic proteins expression after oxygen-glucose deprivation, whereas lentiviral overexpression of the mi

299 unchanged at P28 and P104 following sensory deprivation, whereas nrg3 expression by excitatory neuro

300 MJD3 signaling epigenetically links nutrient deprivation with hepatic autophagy and lipid degradation