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1 in the absence of STAT1, affected genes are derepressed.
2 bsent from flam in the strain where they are derepressed.
3 however, only ST7 becomes transcriptionally derepressed.
4 3 and Gat1 are nuclear, and transcription is derepressed.
5 s compact, while background transcription is derepressed.
6 ire basis by which AbrB-controlled genes are derepressed.
7 e amino acids are among the last genes to be derepressed.
8 ermal stem cells, and Notch targets were not derepressed.
9 activates the general amino acid control non-derepressing 2 (GCN2) enzyme system increasing phosphory
10 in transformed human embryonic kidney cells derepressed ~2600 genes, generating a gene expression pr
16 r1, and propose that the ability of pmar1 to derepress alx1 and delta is regulated by the unequal div
18 ing, Ptch1 is removed from cilia, and Smo is derepressed and accumulates in cilia where it activates
19 ansposable elements become transcriptionally derepressed and activate a type-I interferon (IFN-I) res
20 ctivating ganglia gene expression is totally derepressed and challenge the current models in that est
25 in association with GW182 while selectively derepressing and increasing translation of specific mRNA
26 it unable to restrain ZEBRA, thereby further derepressing and sustaining its expression to culminate
27 , Ifi27l2a, and Hmga2 were transcriptionally derepressed, and the H3K27me3 levels in these gene promo
28 ver, under DNA damaging conditions, RAD53 is derepressed, and the increased level of Rad53p triggers
29 wing LPS stimulation, the IRAK-M promoter is derepressed, and transcription is induced to allow its e
33 ized such that FrmR is modified and frmRA is derepressed at lower [formaldehyde] than required to gen
34 taining antibody to NGF, all viral genes are derepressed at once without requiring de novo protein sy
35 s in ganglionic organ cultures all genes are derepressed at once, thus obviating the need for VP16 to
38 ise, overexpression of human eIF2gamma-I259M derepressed ATF4 messenger RNA translation in human cell
41 PI) and small molecule (FX1) BCL6 inhibitors derepressed BIM and synergized with the BH3-mimetic ABT-
42 omirs specific to miR-26a into neonatal mice derepressed both Smad expression and activity and conseq
43 target repressed by the CRISPR system can be derepressed by expressing an asRNA that sequesters a sma
48 r finding that most genes subject to XCI are derepressed by this erosion of XCI suggests that it shou
49 by the nucleoid structuring protein H-NS and derepressed by VirB, a DNA-binding protein that displays
52 n the absence of p53 function, the resulting derepressed CD44 expression is essential for the growth
54 , we show that the transcription factor E4f1 derepresses cdx4 by dissociating corepressor proteins fr
55 ith a silenced HMR locus persist in recently derepressed cells for several generations at levels of S
56 icient to mediate these effects in long-term-derepressed cells suggests that a cis-acting, chromatin-
58 iffers markedly from both fully silenced and derepressed chromatin structures regarding nucleosome ar
59 e-resistant Pseudomonas aeruginosa [26], and derepressed chromosomal beta-lactam and extended-spectru
61 asing miR-483 and miR-551a expression, which derepresses creatine kinase expression and allows energy
64 t has been hypothesized that photoexcitation derepresses CRY2 by disengaging its C-terminal domain fr
66 cells, extracellular signals are required to derepress developmental promoters to drive lineage speci
67 ent paradox, demonstrating that loss of Ezh2 derepresses different expression programs during disease
70 ression toward the end of floral development derepressing downstream cell wall biosynthesis genes to
71 tes, but in them harmful Stellate genes were derepressed due to the absence of Su(Ste) piRNAs, and me
72 by KSHV LANA and report that these genes are derepressed during de novo lytic infection with the RRVD
74 ed in zinc mobilization and conservation are derepressed during mild zinc deficiency, whereas the ene
80 iquitous Elav has regulatory capacity, since derepressed Elav can stabilize an Elav-responsive sensor
82 us TSG in this genomic region, significantly derepressing endogenous retrovirus (ERV)3-1, with promot
87 tream silencing element, matA SE, results in derepressed expression from wild-type (wt) promoter elem
88 eted deletion of ESRRA and ESRRG in hiPSC-CM derepressed expression of early (transcription factor 21
91 um with short, branched-chain fatty acids or derepressing expression of genes for de novo ILV synthes
93 ) that contain microRNA-binding sites, which derepresses FIH1 protein and represses hypoxia response.
94 which eight are structurally unrelated, that derepress flavonoid accumulation in the presence of flg2
96 pe region during meiosis and several mutants derepressed for centromeric gene expression during mitot
97 ene expression during mitotic growth are not derepressed for centromeric recombination during meiosis
102 318M mutation impaired yeast cell growth and derepressed GCN4 expression, an indicator of defective e
104 t was activated only by drug treatments that derepress gene silencing by reversing DNA hypermethylati
105 g exposure than anticipated was essential to derepress gene silencing in significant cell numbers, an
106 c acid, a known ligand for the NCoR complex, derepresses gene 50 expression and enhances MHV68 lytic
107 al induction during late G(1) phase and also derepresses gene expression in G(1)-phase cells prior to
108 e transcript profiling analysis revealed 544 derepressed genes in a vim1/2/3 triple mutant, including
113 s study demonstrates that anti-miR33 therapy derepresses genes that enhance mitochondrial respiration
114 which binds to and inactivates SinR, thereby derepressing genes for matrix production as well as the
115 transcription of neuronal genes in ES cells, derepressing genes with distal, but not genes with proxi
116 endent gene programming is in establishing a derepressed genetic state susceptible to transactivation
117 , where downstream Hh signal transduction is derepressed, giving rise to superficial BCC-like tumors.
118 ion inhibits production of the mature miRNA, derepresses glycerol-3-phosphate dehydrogenase 1-like en
121 abolishes residual methylation on H3K27 and derepresses H3K27me3 target genes, demonstrating a role
124 the cpxR transcriptional response regulator derepresses hlyA expression, leading to enhanced Caspase
125 eported that ilvA pseudo-revertants having a derepressed hom-thrCB operon appear in the presence of t
126 I1-induced ubiquitylation of H2A and thereby derepresses homeobox HOXC5 and HOXC13 gene expression.
127 IGFBPs in tumor cells treated with EGFR TKIs derepresses IGFIR signaling, which in turn mediates resi
129 rs of subtelomeric genes were preferentially derepressed in a cohesin mutant, whereas SIR binding was
133 borating and p53-suppressing gene, Jdp2, was derepressed in an Hdac1/2-dependent manner and critical
141 d activate transcription when epigenetically derepressed in FSHD, resulting in the pathological misex
142 expressed in the yolk sac are significantly derepressed in GW182(gt/gt) mutant mice, although levels
144 ession of fatty acid synthesis genes was not derepressed in LXRalpha-deficient hosts, indicating that
145 In ThPOK-deficient mice, such expression was derepressed in MHC class II-selected thymocytes, which c
146 Elav and a transgenic elav 3' UTR sensor are derepressed in mutant clones of mir-279/996 We also obse
150 more, we show that retrotransposon mRNAs are derepressed in Tex19.1(-/-) placentas and that protein e
153 R-BINDING transcription factors, which, when derepressed in the adult phase, induce the expression of
162 ne indicated that Aurora A was overexpressed/derepressed in these tumor cells, confirming that INI1/h
166 ine-sensitive inositol auxotrophy, yet fully derepress INO1 and other Opi1p-regulated genes when grow
167 hate, exhibit inositol auxotrophy, yet fully derepress INO1, encoding inositol-3-phosphate synthase.
168 tional isoform of Osteopontin, termed Opn-i, derepressed interleukin-27 (IL-27) secretion and prevent
169 ays serve as surveillance of cells that have derepressed intragenomic parasites due to DNA hypomethyl
173 of hpRNA activity, since knockout of hpRNA1 derepresses its target ATP synthase-beta in testes and c
174 , lincRNA-p21 levels declined, which in turn derepressed JunB and beta-catenin translation and increa
175 perR null allele, the perR991 allele (F51S) derepresses KatA, but not Fur, which likely accounts for
177 ted AML and observed that PPARgamma agonists derepressed KLF4 and were preferentially toxic to CDX2+
183 Intraventricular anti-miR-155 treatment derepressed microglial miR-155 targeted genes, and perip
184 ach partially restored expression of several derepressed miR-155 targets in tumor-infiltrating, miR-1
186 ng cancer cell lines, ZEB1 activated PI3K by derepressing miR-200 targets, including amphiregulin (AR
188 inal binding protein 2 (CtBP2) but not CtBP1 derepressed Mitf and REST expression and enhanced melano
189 here we report translationally repressed and derepressed mRNA isoforms during neocortical neurogenesi
190 system, can be used to reversibly repress or derepress multiple target genes simultaneously, allowing
191 cA production, reduced CovR phosphorylation, derepressed multiple CovR-regulated virulence factors (s
192 pump efflux, and suggest selection for more derepressed mutants may occur during mixed infections.
193 InrS binds Ni(II) sufficiently tightly to derepress Ni(II) export at concentrations below K(D) Ni(
196 or overexpression of phospholipase C (TbPLC) derepresses numerous silent ESs in T. brucei bloodstream
198 However, pharmacological inhibition of Rho derepresses only a small fraction of these transcripts.
199 the absence of sperm, egrh-1 mutants exhibit derepressed oocyte maturation marked by MAPK activation
200 Inhibition of ET receptor activity also derepresses OPC differentiation in the corpus callosum i
202 ing recalcitrant mutations, in part, through derepressed PacC levels resulting in traces of PacC(27)
203 ent mechanism of ranibizumab action involved derepressing PDGFs, which, at the concentrations present
205 epressed differentiation-inducible genes and derepressed pluripotency-associated genes in ES cells.
206 infection of Ahr(-/-)mice recapitulated the derepressed PMN recruitment observed previously in Ido1(
207 cp1 coordinates Cdk1 and Gwl inactivation to derepress PP2A-B55, generating a dephosphorylation switc
208 rved upstream ORF present in the mRNA leader derepress PRL protein synthesis and attenuate the transl
209 lly regulated the ability of BH3 mimetics to derepress proapoptotic molecules from anti-apoptotic pro
210 cing BRCA1-IRIS in ovarian cancer cell lines derepressed PTEN expression along with the antiapoptotic
216 eta3-tubulin, synaptophysin, and others) are derepressed, resulting in acquisition of neuronal phenot
217 utated, expression from the STK promoter was derepressed, resulting in ectopic expression in the infl
219 tant, iron uptake and utilization genes were derepressed, roughly combining the phenotypes of the sin
220 Loss of KLF4 in monocytes transcriptionally derepresses Runt-related transcription factor 3 in respo
222 on of both Rev-erbs in liver synergistically derepresses several metabolic genes as well as genes tha
223 RNA-interference-mediated depletion of SMCX derepresses several of these targets and simultaneously
224 he NIH3T3-based Shh-light cells, it fails to derepress Shh- or a Smo-agonist-induced inhibition of Gl
225 ts its interaction with stargazin, therefore derepressing SR activity, leading to more D-serine produ
226 ion of FoxO3a, consistent with it being in a derepressed state capable of regulating transcriptional
227 ynergistically tipped the balance toward the derepressed state, revealing a concerted action of the t
231 y, the well-conserved general AA control non-derepressing system of yeast was discovered to be activa
234 ical and transcriptional dysregulation, with derepressed target gene enrichment limited to circadian
236 an cancers, thereby promoting oncogenesis by derepressing targets such as HMGA2, K-Ras and c-Myc.
238 idated targets of these microRNAs implicated derepressed TGF-beta signaling as a shared seizure-modif
239 sociation from Rev-erbbeta has been shown to derepress the expression of target genes in response to
240 n-regulation of miR-29 would be predicted to derepress the expression of these mRNAs and enhance the
243 confirm that the mechanism by which the Duts derepress the SaPI cycle depends on dUTP and involves bo
247 ing protein FleQ from Pseudomonas aeruginosa derepresses the expression of Pel exopolysaccharide gene
248 anscriptional regulator in Escherichia coli, derepresses the expression of the export proteins RcnAB
252 ETS family proteins to the Ets/E-box motifs derepresses the hTERT promoter by inducing an active pro
265 e alpha2 repressor in the starting state are derepressed to establish the new mating-type-specific ge
268 (DeltaN) knockout reduced PRC1 occupancy and derepressed transcription at distal RE1 elements but inc
269 depletion of the PRC1 members or UBR5 alone derepressed transcription elongation at these sites, sug
273 ith decreased Flt3 expression and that Mysm1 derepresses transcription of the Flt3 gene by directing
277 UUG codons, and compound substitutions also derepress translation of GCN4, indicating slower TC recr
279 owth, impairs general protein synthesis, and derepresses translation of GCN4 mRNA, encoding a transcr
280 many of the cleavage sites sensitized in the derepressed TRCF are partially or completely buried to p
283 hypoxia-inducible factor 1 (HIF-1), FIH1, is derepressed under these conditions and suppresses HIF tr
284 In the first class the hom-thrCB operon was derepressed unmasking the threonine dehydratase activity
286 e primary response genes whose expression is derepressed upon COI1-dependent turnover of a labile rep
287 that some target genes of nuclear SIRT3 are derepressed upon degradation of SIRT3 caused by stress s
290 promoted EGF-mediated epithelial invasion by derepressing upstream EGF receptor, SRC tyrosine kinase,
291 igase of herpes simplex virus 1 (HSV-1), can derepress viral genes by degrading ND10 organizers to di
293 ons deficient for Brg, Shh target genes were derepressed, whereas Brg-deleted cerebellar granule neur
294 nes involved in seed maturation are markedly derepressed with concomitant accumulation of seed 12S gl
295 zh2 eliminates H3K27me3 on Wnt promoters and derepresses Wnt expression, which leads to activation of
298 methylation reduces YAP phospho-S127, which derepresses YAP1, and actively supports YAP1 activation
299 system in the fat bodies, which subsequently derepresses yolk protein precursor genes and makes them