ライフサイエンスコーパス: dermis

1 the skin layers and deposition at the upper dermis.

2 n skin, large amounts of HA are found in the dermis.

3 differentiation in the developing reticular dermis.

4 marrow-derived fibrocytes accumulate in the dermis.

5 on forces on and move directionally over the dermis.

6 clerosis, it can occur in all regions of the dermis.

7 ng of capillary thromboses (CT) in the upper dermis.

8 ansition between the papillary and reticular dermis.

9 ltration of skin homing lymphocytes into the dermis.

10 r matrix (ECM) remodelling in the underlying dermis.

11 d in the skin of mammals, most likely in the dermis.

12 monocyte-derived DCs were predominant in the dermis.

13 cells present in the papillary and reticular dermis.

14 , and a mixed inflammatory infiltrate in the dermis.

15 ae and associated muscle, tendons and dorsal dermis.

16 HSP70 can be found in both the epidermis and dermis.

17 ely generated around each microneedle in the dermis.

18 at the dermoepidermal junction and/or in the dermis.

19 opulation (gammadeltaT17 cells) in the mouse dermis.

20 nduces cutaneous fibers to die back into the dermis.

21 sal cell carcinoma stroma compared to normal dermis.

22 s inflammation surrounding tattoo ink in the dermis.

23 ifferentiation in developing and adult mouse dermis.

24 ed to regenerate HFs when combined with aged dermis.

25 but also within the papillary and reticular dermis.

26 onal collagen I gel, a representative of the dermis.

27 and increased numbers of fibroblasts in the dermis.

28 and 7.6+/-5.6 mum for the transition zone-to-dermis.

29 infected the epidermis and HCMV infected the dermis.

30 phils, macrophages, and T lymphocytes in the dermis.

31 t on other epithelial compartments or on the dermis.

32 ion by CD11c(+) dendritic cells (DCs) in the dermis.

33 with mononuclear cell infiltration into the dermis.

34 -Asp (RGD)-binding integrins in the inflamed dermis.

35 position and subsequent diffusion within the dermis.

36 tazarotene to the pilosebaceous unit of the dermis.

37 typic skin cultures comprising epidermis and dermis.

38 ratosis, and inflammatory infiltrates in the dermis.

39 nd other inflammation-related changes in the dermis.

40 mimicking the in vivo pathophysiology of the dermis.

41 ustered around the central arterioles of the dermis.

42 mechanoreceptors that remained deeper in the dermis.

43 or tunable penetration into the epidermis or dermis.

44 trastructure to possible changes in the skin dermis.

45 ominant gammadelta cell in the epidermis and dermis.

46 um granulosum (SG), stratum basale (SB), and dermis.

47 ced micro-vacuolization in the epidermis and dermis.

48 njection of ink and/or dye pigments into the dermis.

49 ient to estimate the volume deposited in the dermis.

50 al melanomas that invade into the underlying dermis.

51 are impaired in their maintenance within the dermis.

52 reach the blood vessels in the vascularized dermis.

53 on and denser neutrophil infiltration in the dermis.

54 ettings were not seen in the inflamed murine dermis.

55 Th1 and Th2 cell navigation of the inflamed dermis.

56 rmis, although also evident in the papillary dermis.

57 albicans in subepithelial layers such as the dermis.

58 al reprogramming and eventually invading the dermis.

59 esent in the underlying viable epidermis and dermis.

60 aration of the epidermis from the underlying dermis.

61 sebaceous glands relative to the surrounding dermis.

62 igmented melanocytes that extend through the dermis.

63 and deposit it at the lower epidermis/upper dermis.

64 The total area of apical dermis (0-30 mum) contained approximately 10-fold more m

65 CD200(+) cells in SCC stroma than in normal dermis (180.8 cells/mm(2) vs 24.6 cells/mm(2)) (P<.01).

66 elanosomes in the exterior-most layer of the dermis [7, 8] and that this layer lacks the unpigmented

67 ive growth of placode keratinocytes into the dermis, a crucial step in skin appendage formation.

68 s a rare mesenchymal neoplasm arising in the dermis, accounting for less than 0.1% of all cancers.

69 extracts from stratum corneum, epidermis and dermis after 24h, and the results were compared to those

70 The amount of SP and KP retained in dermis after topical application of NLC-R11 was signific

71 and monocyte-derived dendritic cells in the dermis after VACV scarification.

72 ccumulation of mast cells and CD3+T-cells in dermis, all of which were observed in mice in which the

73 As peripheral nerves ramify within the dermis, all the nuclei along their course belong to glia

74 axa, transmission electron microscopy of the dermis also showed pronounced changes in the structure a

75 -dose allergen inoculation directly into the dermis, an immunologically active area containing abunda

76 (HA) and versican are key components of the dermis and are responsive to ultraviolet (UV)B-induced r

77 eration of hair follicles, sebaceous glands, dermis and cartilage.

78 eductions in CD1a(+) Langerhans cells in the dermis and CD11c(+) dermal dendritic cells were observed

79 , fibroblast density declined throughout the dermis and clones of fibroblasts became more dispersed.

80 Wnt signals within the epidermis and dermis and crossing between the epidermis and dermis hav

81 eria were consistently detectable within the dermis and dermal adipose of normal human skin.

82 Sequencing of DNA from dermis and dermal adipose tissue identified bacterial 16

83 defects were accompanied by a rupture of the dermis and detachment of the epidermis.

84 on Y. pestis-neutrophil interactions in the dermis and dLN very early after infection.

85 higher recruitment of neutrophils to the ear dermis and ear draining lymph nodes (dLN) as early as 6-

86 We compare dermis and endometrium capacities to support trophoblast

87 Cutaneous nerves extend throughout the dermis and epidermis and control both the functional and

88 Radiation-induced changes in the dermis and epidermis were accompanied by an infiltrate o

89 Beyond anchoring of LTMRs to the surrounding dermis and epidermis, recent evidence suggests that the

90 eptor subtypes and their location within the dermis and epidermis.

91 asia and infiltration of leukocytes into the dermis and epidermis.

92 uperficial microdisruptions in the papillary dermis and epidermis.

93 roughout the inter-follicular regions of the dermis and form clusters with antigen presenting cells a

94 dings reveal adaptations of Y. pestis to the dermis and how these adaptations can define the progress

95 degranulation was equivalent for MCs in the dermis and hypodermis of all three strains, but only the

96 llicle morphogenesis or establishment of the dermis and hypodermis.

97 we defined a new role for fibroblasts in the dermis and identified a minimal set of cell types for sk

98 delta T cells establish residence within the dermis and identify a role for S1PR2 in restraining the

99 ncluding interstitial dendritic cells of the dermis and Langerhans cells of the epidermis, in a dose-

100 k somites, the progenitors that give rise to dermis and muscle.

101 omyoblastlike neoplastic cells involving the dermis and often extending to subcutaneous tissue.

102 d composed of stratified epidermis, fat-rich dermis and pigmented hair follicles that are equipped wi

103 can introduce immunogenic particles into the dermis and potentiate local or systemic hypersensitivity

104 lter the balance of S. aureus entry into the dermis and provide an explanation for how such dermal dy

105 ight scattering from collagen fibrils in the dermis and refractive index mismatch owing to the presen

106 In the dermis and subcutaneous fat, the EVE treated groups show

107 Cellulitis is an infection of the deep dermis and subcutaneous tissue, presenting with expandin

108 SCH) is a rare, benign vascular tumor of the dermis and subcutis.

109 uytren's disease, a fibrotic disorder of the dermis and subdermal tissues of the palm.

110 reatment quickly clears spirochetes from the dermis and that the rash appearance is not indicative of

111 relevant levels into both the epidermis and dermis and that the skin-penetrating aptamer retains its

112 hat stabilize the cohesion between the upper dermis and the basement membrane zone.

113 in a process that bypasses the epidermis and dermis and their attendant innate and adaptive immune at

114 ormal density but were located deeper in the dermis and their capsule appeared partially empty.

115 rmore, rVN bound to VG1Fs extracted from the dermis and to nondenatured versican but not to fibrillin

116 rich epidermis and extracellular matrix-rich dermis and to show that conventional histological and im

117 that involves dermatophytic infection of the dermis and/or lymph nodes and sometimes the central nerv

118 agen deposition leading to thickening of the dermis and/or subcutaneous tissues and may cause signifi

119 onstituents of human skin connective tissue (dermis) and are essential for maintaining mechanical str

120 top-view (skin wheal), underside (below the dermis), and cross-section (true skin bleb) perspectives

121 ological cues alone also migrate through the dermis, and break in lymphatics, indicating that the abi

122 iocompatible materials, absorbable implants, dermis, and collagen.

123 They could also adhere to brain, lung, dermis, and heart endothelial cells, suggesting cerebral

124 cures the attachment of the epidermis to the dermis, and its mutations cause a human skin fragility d

125 cy and monocytopenia were observed in blood, dermis, and lung lavage fluid.

126 stasis of mature DCs or pre-DCs in the lung, dermis, and spleen.

127 nical problems in adipose tissue, cartilage, dermis, and tendon are discussed that inspire the need t

128 to the suprabasal epidermis, deeper into the dermis, and was maintained in metastases.

129 ic neutrophilic infiltrate in the epidermis, dermis, and/or hypodermis and are often associated with

130 ineage initiate allergic immunity and in the dermis are marked by their expression of CD301b.

131 g in the lamina propria of the colon and the dermis, as well as in microglia.

132 haps even dendritic cells (DCs) in the outer dermis, as well as to lesion infiltrating activated T ly

133 ngly, YAP is expressed in the nucleus in the dermis at 2 and 7 days after wounding.

134 ssion becomes more widespread throughout the dermis at later developmental stages, we use tamoxifen-i

135 e gene expression profiling of back and tail dermis at P1 and dorsal fibroblasts at P2 and P50 showed

136 anoma grows in the epidermis and invades the dermis before metastasizing.

137 Z normally localizes to the cytoplasm in the dermis but is distributed in both the nucleus and cytopl

138 for ASC proliferation and maintenance in the dermis, but not in other WATs.

139 er, Lgr5-expressing cells contribute to this dermis, but not the blastema, during digit tip regenerat

140 uced the overall number of infected cells in dermis by 65%.

141 alian host after they are deposited into the dermis by a sand fly vector.

142 he immune response to P. acnes in the murine dermis by controlling neutrophil recruitment to the infl

143 s and infiltration of both the epidermis and dermis by neutrophils and eosinophils, resulting in form

144 The mild inflammatory milieu created in the dermis by skin laser microporation itself most likely fa

145 eneic fibroblasts injected directly into the dermis can mediate transient disease modulation, autolog

146 eneic fibroblasts injected directly into the dermis can mediate transient disease modulation, autolog

147 inherent structural instability of the RDEB dermis, combined with repeated injury, increased the bio

148 e differences in the proportion of 5-MTHF in dermis compared with epidermis.

149 ion of cells in lesional epidermis (EPI) and dermis, compared with the corresponding non-lesional reg

150 melanocytes displayed invasion into adjacent dermis, consistent with loss of invasion-suppressing act

151 Since the underlying dermis consists primarily of fibroblasts, we have now ex

152 ic fibers in the synovial membrane and upper dermis contribute to the pain-related behavior associate

153 lieved that site-specific fibroblasts in the dermis control postnatal skin identity by modulating the

154 hibition of neutrophil infiltration into the dermis, demonstrating that DM keratinocytes produced les

155 between healthy and tumor skin surfaces and dermis, demonstrating that the change in microbiota comp

156 Brown adipocytes and muscle and dorsal dermis descend from precursor cells in the dermomyotome,

157 t dermal DCs unexpectedly accumulated in the dermis despite their actomyosin-dependent migratory capa

158 re reduced, indicating cDC2s in the lung and dermis develop via different pathways.

159 hen Hh signalling is inhibited the reticular dermis does not respond to epidermal beta-catenin activa

160 oliferative phase during which growth in the dermis dominates healing.

161 etrium, the natural trophoblast target, with dermis dramatically reduces trophoblast interstitial inv

162 amplifying Wnt activity throughout the wound dermis during a crucial phase of skin regeneration.

163 te senescent cells in both the epidermis and dermis during aging.

164 ignals derived from mesenchymal cells in the dermis during skin morphogenesis and regeneration.

165 ed accumulation of infiltrating cells in the dermis, elevated expression of IFN-gamma, CCL5, CCL8, an

166 Conditional deficiency of Cyp26b1 in the dermis (En1Cre;Cyp26b1f/-) results in decreased hair fol

167 A-285222 treatment enhanced dermis endothelial NO synthase expression and plasma NO

168 ignaling leads to the formation of thickened dermis, enlarged epidermal placodes and dermal condensat

169 l ethanolamides, and sphingolipids, in human dermis, epidermis, and suction blister fluid.

170 nd maintains antigen-presenting cells in the dermis/epidermis.

171 irochete transmits from the tick to the host dermis, eventually colonizing and persisting within mult

172 erstitial fluid from the epidermis and upper dermis, exposing the powder to epidermal tissues.

173 m responsible for the action of TIP39 in the dermis, fibroblasts were cultured in three-dimensional c

174 Burrowing through the dermis filariae exclusively enter pre-collecting lymphat

175 ay quantified aptamer from the epidermis and dermis, giving levels far exceeding the cellular half ma

176 All DM dermis had increased OPN compared with healthy skin.

177 ermis and crossing between the epidermis and dermis have distinct roles and specific functions in ski

178 movements in the chronically infected mouse dermis imaged by intravital microscopy.

179 -opsonized Y. pestis with neutrophils in the dermis in a mouse model of bubonic plague.

180 nocytes at the junction of the epidermis and dermis in benign neoplasms.

181 mic modification occurs in the epidermis and dermis in CD1 transgenic mice following either intraperi

182 This transition is limited to the upper dermis in several inflammatory skin diseases, yet in sys

183 tro, penetrating deep into the epidermis and dermis in skin of both species.

184 s) have been identified in extracts from the dermis in which hyaluronan (HA)-versican-fibrillin compl

185 One forms the upper dermis, including the dermal papilla that regulates hair

186 The other forms the lower dermis, including the reticular fibroblasts that synthes

187 rrence of senescent fibroblasts in geriatric dermis, increase the dermal expression of IGF-1, and cor

188 The biophysically altered dermis increased myofibroblast activity and integrin bet

189 tonergic fibers extended from the underlying dermis into the papillar base.

190 n the host, sporozoites navigate through the dermis, into the bloodstream, and eventually invade hepa

191 Host defense of the epidermis and dermis involves the interplay of many cell types to enab

192 The ability of cells to invade into the dermis is a critical event in the development of cutaneo

193 bers of DCs, including XCR1(+) DCs, the skin dermis is an attractive site for vaccine administration.

194 of IL-17-committed gammadelta T cells in the dermis is important in promoting tissue immunity.

195 hat microbial population of skin surface and dermis is related to mast cell tumor.

196 ution of nectin-1 and HVEM in the underlying dermis is still open.

197 that active macrophages are cleared from the dermis is the principle determinant of rash morphology.

198 d human dermis: the skin is wrinkled and the dermis is thin and composed of loose, disorganized, and

199 Once inoculated into the host dermis, it disseminates to various organs including dist

200 hypodermis layer, were present in the upper dermis layer within proximity to in situ melanoma cells,

201 Vector-borne infections initiated in the dermis likely involve adaptations to this unique microen

202 a CD141(hi) DC present in human interstitial dermis, liver, and lung that was distinct from the major

203 e SPPs (SPACE peptide, TD-1, polyarginine, a dermis-localizing peptide and a skin penetrating linear

204 gulated proliferation of melanoblasts in the dermis may be critical for production of epidermally-bou

205 This suggests that another cell in the dermis may sense allergens and relay that information to

206 After Cath LL-37 injection into the dermis, MC-deficient B6.Cg-Kit(W-sh)/HNihrJaeBsmJ (KitW-

207 The dermis model resulted in a larger receptive field, as th

208 Receptive fields for the epidermis and dermis models were constructed by mapping the long-axis

209 gs were readily detectable in the uninflamed dermis, most were nonmotile.

210 ; despite often being deeply embedded in the dermis, no other species has been reported as feeding on

211 liminary data on bacterial population of MCT dermis, obtained only on three dogs, demonstrated an int

212 appeared in large focal accumulations in the dermis of AGW specimens.

213 g CD68(pos) macrophages were detected in the dermis of atopic dermatitis (AD) skin lesions.

214 We compare epidermis and dermis of both sun-protected and sun-exposed skin derive

215 he proportion of IL-22(+) GDL T cells in the dermis of CCR6 KO mice (vs WT mice), suggesting that eff

216 in fibroblasts from the palmar and nonpalmar dermis of Dupuytren's patients and palmar fibroblasts fr

217 3.4-fold and 2.7-fold, respectively, in the dermis of elderly (>80 years) versus young (21-30 years)

218 howed that>40% of drugs were retained in the dermis of excised neonatal porcine skin up to 24h post-M

219 tic narrow zone in the superficial papillary dermis of healthy human skin.

220 y tissue-resident dendritic cell (DC) in the dermis of human skin that is characterized by surface ex

221 -like properties have been identified in the dermis of human skin.

222 Cs creates an in vivo synthetic niche in the dermis of immunodeficient mice driving the differentiati

223 ype VI collagen was expressed throughout the dermis of intact human skin, at the expanding margins of

224 was performed to separate the epidermis and dermis of lesional and nonlesional skin from patients wi

225 reus was observed to be more abundant in the dermis of lesional skin from AD patients.

226 atment on the aortic ultrastructure and skin dermis of MFS mice through immunohistochemical evaluatio

227 Fibrin placed into the dermis of mice underwent cellular endocytosis and lysoso

228 Collagen introduced into the dermis of mice underwent cellular endocytosis in a parti

229 -derived cell population is increased in the dermis of MRI contrast-treated rodents.

230 signalling was highly upregulated in healing dermis of P21 compared with P2 mice.

231 tially expressed gene products in the EPI or dermis of psoriasis lesions.

232 mast cell (MC) numbers are increased in the dermis of rosacea patients.

233 The dermis of TGFbeta1-overexpressing mice had significantly

234 abaxial musculature and forms ventrolateral dermis of the interlimb body wall.

235 basement membrane of the tick midgut and the dermis of the mammal.

236 autonomic sympathetic fibers into the upper dermis of the skin, an area that is normally devoid of t

237 eous mechanoreceptor located deep within the dermis of the skin, detects high frequency vibrations th

238 neutrophil infiltration in the epidermis and dermis of the skin, leading to disease manifestations.

239 o improperly increased their distribution in dermis of the skin.

240 que layer of adipocytes within the reticular dermis of the skin.

241 e through the barrier into the epidermis and dermis of the skin.

242 matrix assembly and cell function within the dermis of the skin.

243 nin pathway is activated most notably in the dermis of the wound bed early (d 2) after injury and sub

244 bit skin, chosen as a model material for the dermis of vertebrates.

245 but the total numbers of GDL T cells in the dermis of WT and CCR6 KO mice were equivalent.

246 microdialysis probes were inserted into the dermis on the dorsal aspect of the forearm in 15 young,

247 When introduced into dermis or bleomycin-injured lungs of mice, collectins MB

248 presence of pathogenic microorganisms in the dermis or lungs elicits a robust gammadelta17 response t

249 monstrate that nociceptive fibers within the dermis play a crucial role in antifungal defenses throug

250 eus penetrates the epidermis and reaches the dermis, polymorphonuclear leukocytes (PMLs) accumulate a

251 id infiltrate was observed in the underlying dermis, predominantly composed of CD3+ T cells, scattere

252 Vaccine delivery into the dermis, recruitment of neutrophils, macrophages, dendrit

253 ating gammadelta T cell retention within the dermis remain poorly understood.

254 included lobules of small vessels within the dermis, resembling a tufted angioma.

255 +) neonatal fibroblasts from upper and lower dermis, respectively, confirmed that Sca1(+) cells had a

256 s transiently increased in the epidermis and dermis, respectively.

257 Inoculation of the ear dermis resulted in higher frequencies of total and infec

258 The dermis revealed enhanced lymphatic vessel density, and t

259 ets including RORgamma(+) ILC3s into wounded dermis; RORgamma(+) ILC3s are potent sources of IL17F in

260 s inside tissues of live mice, including the dermis, skeletal muscle and brain.

261 This gene was expressed in the dermis, skeletal muscles, periocular mesenchymal-like ce

262 iltrating tumour cells extending through the dermis, subcutis, orbicularis muscle bundles and nerve f

263 and progressive pathological changes in the dermis, such as those seen in ageing.

264 ost immune cells while migrating through the dermis, suggesting the importance of B. burgdorferi moti

265 4+ spindle cells, and increased mucin in the dermis, supporting the diagnosis of NSF.

266 B irradiation and penetrates deeper into the dermis than UV-B irradiation.

267 In epidermis and dermis, the critical DCs are TNF-producing and IL-1beta-

268 ype in COL1A2-CCN1 mice resembles aged human dermis: the skin is wrinkled and the dermis is thin and

269 the epidermis, but a minimal presence in the dermis, thereby reducing the likelihood of FLUO entering

270 sults show the microbiota extends within the dermis, therefore, enabling physical contact between bac

271 und healing and increased skin hydration and dermis thickness.

272 recruitment and maturation of MCs within the dermis through SCF production by LTA-stimulated keratino

273 arrange the collagenous fibre network of the dermis to form a collagen-free zone at the wound centre.

274 the ribs and vertebrae that expand into the dermis to form plate-like shell components.

275 A signal first arising in the dermis to initiate the development of hair follicles has

276 of odontogenic competence from the external dermis to internal epithelium soon after the origin of j

277 ting from the neural crest must traverse the dermis to reach the epidermis of the skin and hair folli

278 along the developing embryo and traverse the dermis to reach the epidermis, colonising the skin and e

279 Peripheral nerves pass from the dermis to the epidermis via small fenestrae in the sub-e

280 oppose gammadelta T cell migration from the dermis to the skin draining lymph node (dLN).

281 omoted the formation of blood vessels in the dermis underlying the HPV-induced lesions.

282 at the transition from the epidermis to the dermis underneath, which determines the drug distributio

283 Delivery of vaccine formulations into the dermis using antigen-coated microneedle patches is a pro

284 the percentage of 5-MTHF of the total in the dermis was similar to that in other organs, it was espec

285 unt immunofluorescence staining of the human dermis, we demonstrated the three-dimensional distributi

286 ring in situ tensile testing of sea cucumber dermis, we investigate the ultrastructural mechanics of

287 nests, and nucleated cells within papillary dermis, were more frequently found in this subtype.

288 levels of siRNA to the basal epidermis/upper dermis where melanoma cells reside.

289 lk tips are implanted in the epidermis/upper dermis where they release vaccine over a time period det

290 presence in large numbers in the superficial dermis, where Leishmania is encountered, suggests that t

291 was found to spread into the upper papillary dermis, whereas S100A9 was shown to induce fibroblast pr

292 ntrols adipogenic cell fate within the lower dermis, which potentially contributes to the pathogenesi

293 ) showed a few melan-A-positive cells in the dermis, which was insufficient for a diagnosis of invasi

294 paths for drug and vaccine delivery into the dermis while maintaining integrity of the skin by quick

295 Cs regenerated HFs when supported with young dermis, while young HFSCs failed to regenerate HFs when

296 studies showed marked edema of the papillary dermis with an inflammatory infiltrate consisting mainly

297 By co-culturing decellularized dermis with keratinocytes, fibroblasts and immune cells

298 ct dermo-epidermal junction and more compact dermis with loss of adnexal structures.

299 to deliver botulinum toxin A into the human dermis with the aim of reducing patient pain, improving

300 cargo distributed both in the epidermis and dermis, with acquisition by CD11c(+) dendritic cells (DC