ライフサイエンスコーパス: desaturation

1 second H abstraction adjacent to the first (desaturation).

2 PD) and resting or exercise-induced moderate desaturation.

3 identified pore-scale event during capillary desaturation.

4 of the amygdala reproduced the apnea and O2 desaturation.

5 oxylation, halogenation, ring formation, and desaturation.

6 ion of the C2-thioether side chain, and C2/3 desaturation.

7 t all three genes participated in fatty acid desaturation.

8 atial separation of fatty acid synthesis and desaturation.

9 s, 36% of which were for clinically relevant desaturation.

10 om stearoyl-CoA desaturase 1 (SCD1)-mediated desaturation.

11 of respiratory events, and degree of oxygen desaturation.

12 ccompanied by moaning, tachypnea, and oxygen desaturation.

13 lity by uncoupling fatty acid synthesis from desaturation.

14 istinct reactions, C5-epimerization and C2/3-desaturation.

15 correlated with severity of nocturnal oxygen desaturation.

16 tory pressures are noted in conjunction with desaturation.

17 lglycerol substrate based upon the degree of desaturation.

18 one of the 10 controls had sleep-time oxygen desaturation.

19 irways of patients and leads to blood oxygen desaturation.

20 ng desaturase was capable of very-long-chain desaturation.

21 n the characterization of POSA based on a 3% desaturation.

22 in the temperature responsiveness of omega-6 desaturation.

23 3-OH nor 4-OH retinol was an intermediate in desaturation.

24 urs of discharge in infants with and without desaturations.

25 of discharge, and the effect of activity on desaturations.

26 One of the 75 infants with desaturations (1%) and 2 of the 43 infants without desat

27 ong the 118 infants, 59 (50%) had at least 3 desaturations, 12 (10%) had desaturation for more than 1

28 on; p = 0.96) but was associated with severe desaturation (15% vs 9% without noninvasive ventilation;

29 Of the 75 infants with desaturations, 18 (24%) had an unscheduled visit for bro

30 s compared with 11 of the 43 infants without desaturation (26%) (difference, -1.6%; 95% CI, -0.15 to

31 id metabolism and, in particular, fatty acid desaturation(3).

32 Oxygen desaturation (353 patients [5.6%]) and vomiting (328 [5.

33 isplacements (32% vs. 56%; P = 0.01), oxygen desaturations (40% vs. 75%; P < 0.001), required reintub

34 rations (1%) and 2 of the 43 infants without desaturations (5%) were hospitalized within 72 hours (di

35 Of the 75 infants who had desaturations, 59 (79%) had desaturation to 80% or less

36 05), aspiration events (7% vs 9%; p = 0.69), desaturation (8% vs 4%; p = 0.27), and hypotension (13%

37 On further oxygen desaturation, a tonic increase in stellate ganglion acti

38 duces membrane thinning, along with specific desaturation activities.

39 -Dihydrophenanthrene (DHP) gives the highest desaturation activity, the final products being phenanth

40 allergy experienced apnea attack with strong desaturation after an immediate allergic reaction includ

41 chiolitis experienced recurrent or sustained desaturations after discharge home.

42 actors affecting nurses' response to monitor desaturation alarms in postoperative patients on a gener

43 he level of 16:0 exiting the plastid without desaturation also increased to 21%.

44 ow, similar to those in the literature: 8.6% desaturation and 7.4% esophageal placement during intuba

45 ologic inhibition of SCD1 blocked fatty acid desaturation and also exerted antitumor activity in vitr

46 eaction for the transfer of 18:1 into PC for desaturation and also for the reverse transfer of 18:2 a

47 g halogenation, hydroxylation, ring closure, desaturation and aromatic ring cleavage reactions.

48 a-stat strategy increases jugular vein blood desaturation and cerebral oxygen extraction compared wit

49 idity is known to be regulated by fatty acid desaturation and cholesterol, although some cells, such

50 erapeutic interventions to regulate ceramide desaturation and consequent function.

51 explains metabolic plasticity in fatty acid desaturation and constitutes an unexplored metabolic rew

52 FA) composition and calculated indexes of FA desaturation and de novo synthesis by the mammary gland.

53 way collapse during sleep, leading to oxygen desaturation and disrupted sleep.

54 to exercise cessation on cycling and higher desaturation and dyspnea intensity during the 6MWT.

55 In the 6MWT, desaturation and dyspnea were greater in patients with D

56 lipidome with significant reductions in both desaturation and elongation of hepatic neutral lipid spe

57 gh shared food sources and common endogenous desaturation and elongation pathways.

58 ore >10) and an apnea-hypopnea index with 3% desaturation and from 5 to 30 events per hour were rando

59 odel complexes, we investigated pathways for desaturation and hydroxylation by an iron(IV)-oxo active

60 C-H bond activation chemistry of two types, desaturation and hydroxylation, using synthetic manganes

61 progress into non-REM sleep, with continuous desaturation and hypercarbia.

62 P450s in that the predominant oxidation is a desaturation and in that hydroxylation represents only a

63 rases, was bifunctional, and performed a 3,4-desaturation and introduced a C-2 keto group into neuros

64 visitors, chemosensitivity parameters (high desaturation and low ventilatory response to hypoxia at

65 perature shifts by adjusting levels of lipid desaturation and membrane fluidity.

66 de-novo lipogenesis, fatty acid elongation, desaturation and oxidation.

67 pting ventilation, and causing oxyhemoglobin desaturation and poor sleep quality.

68 a cycles during sleep associated with oxygen desaturation and sleep disruption.

69 ThnG catalyzes sequential desaturation and sulfoxidation of PS-5 (5), giving PS-7

70 Subjects demonstrated a modest oxygen desaturation and tachycardia during the procedure that r

71 ctivity of polyunsaturated fatty acid (PUFA) desaturation and the lipid composition in human blood an

72 NHF is associated with better comfort, fewer desaturations and interface displacements, and a lower r

73 hat the three pathways, C3 hydroxylation, C3 desaturation, and C2 hydroxylation/radical rearrangement

74 to reduce the risks with repeated attempts, desaturation, and cardiovascular collapse during emergen

75 ociated with ventilatory limitation, greater desaturation, and dyspnea.

76 e amygdala co-occurred with apnea and oxygen desaturation, and electrical stimulation of the amygdala

77 c pathways including lipogenesis, fatty acid desaturation, and generation of phosphatidylcholine (PC)

78 rmed in response to an adverse event, oxygen desaturation, and vomiting.

79 presence of respiratory disturbances, oxygen desaturations, and cortical arousals within a 90-s hazar

80 with a high likelihood of OSA, postoperative desaturations, and pulmonary complications.

81 Strong bases are avoided in this desaturation approach, and the key is to merge soft enol

82 Oxygen desaturations are accompanied by increases in ETCO2, sup

83 Other oxidase activities, such as C-C bond desaturation, aromatization, and C-C bond formation, wer

84 cs to probe fatty acid metabolism, including desaturation, as a function of oncogene expression and o

85 R, 6.68; 95% CI, 3.83-11.63; P < 0.001), and desaturation at exercise in hypoxia equal to or greater

86 okolow index and T-wave amplitude in V5 with desaturation at exercise.

87 (VO(2)) was depressed and there was systemic desaturation at rest that worsened with exercise.

88 Notably, we observed faster tissue desaturation at the onset of exercise with the arm above

89 Patients exhibiting oxyhemoglobin desaturations at night showed higher plasma triglyceride

90 a pattern preserving the overall saturation/desaturation balance of retinal phospholipids.

91 The mean duration of desaturation below 90% was 69.2 +/- 65.2 s (47; 6-327).

92 children (0.9%) had brief periods of oxygen desaturation below 95%, none of which required airway in

93 8% had desaturations below 80% and 12.5% had desaturations below 70%.

94 ion, with 31 (10.2%) seizures accompanied by desaturations below 80% and 11 (3.6%) seizures below 70%

95 zures had desaturations below 90%, 31.8% had desaturations below 80% and 12.5% had desaturations belo

96 In these 19 seizures, all oxygen desaturations below 85% were accompanied by an increase

97 Pulse oximetry showed oxygen desaturations below 90% in 101 (33.2%) of all seizures w

98 Desaturations below 90% were significantly correlated wi

99 neralized convulsions, 34.8% of seizures had desaturations below 90%, 31.8% had desaturations below 8

100 scar VT ablation, and avoidance of cerebral desaturations below a threshold of 55% may safely guide

101 IB), isolated desaturation (ID) and combined desaturation/bradycardia (DB).

102 affects phosphatidylcholine (PC) fatty acyl desaturation by disturbing the balance between FAD2 and

103 lls, as has been widely shown previously for desaturation by fish and many other organisms.

104 0-CoA into lipids, thereby shielding it from desaturation by Ole1p.

105 augmented the proportion of apneas with O(2) desaturations by 12%.

106 atty acid synthesis, while losing fatty acid desaturation capacity.

107 ecursors through consecutive elongations and desaturations catalyzed, respectively, by fatty acyl elo

108 Whereas overexpression of Ole1p increases desaturation, co-overexpression of Ole1p and Sct1p resul

109 ntubation-associated events or severe oxygen desaturation compared to primary tracheal intubation.

110 This decreased level of fatty acid desaturation corresponded to a decreased transcriptional

111 Our primary outcome was severe desaturation (defined as peripheral oxygen saturation re

112 r greater detail but typically only catalyze desaturation (dehydrogenation) reactions.

113 mination of the severity and duration of the desaturations, delayed hospitalizations within 72 hours

114 hereas overexpressing fads1, unrelated to LA desaturation, did not.

115 Sleep-time desaturation directly correlated with alveolar-arterial

116 This deficiency in desaturation drives an imbalance between the saturated a

117 .422; p<0.01) and events (rho=0.57; p<0.01), desaturation duration (rho=0.505; p<0.01), and SpO2 (rho

118 Although noninvasive ventilation reduces desaturation during intubation of severely hypoxemic pat

119 The aim of this study was to assess oxygen desaturation during sleep in hepatopulmonary syndrome.

120 nding the quantitative control of fatty acid desaturation during the biosynthesis of seed storage oil

121 oup: subcutaneous fat necrosis and transient desaturation during the MRI.

122 tubation-associated events and severe oxygen desaturation during tracheal intubation.

123 d stable COPD with moderate exercise-induced desaturation (during the 6-minute walk test, Spo2 >/=80%

124 nea syndrome without prolonged oxyhemoglobin desaturation, early adenotonsillectomy, as compared with

125 r 10 seconds with no thoracic motion after a desaturation episode.

126 rms) exhibit decreased membrane phospholipid desaturation, especially in phosphatidylcholine.

127 tes), 75 of 118 infants (64%) had at least 1 desaturation event (median continuous duration, 3 minute

128 monitoring hours in 103 patients yielded 342 desaturation events (duration 23.6s [20.99, 26.1]) and 7

129 oneal, leptin decreased the number of oxygen desaturation events in REM sleep, and increased ventilat

130 cheal intubation-associated events or oxygen desaturation events occurred in 40.2% of patients with r

131 65% of patients with desaturation events received interventions which correla

132 ications were for clinically relevant oxygen desaturation, facilitating timely nursing response and i

133 Higher proportions of distal elongation and desaturation fatty acid products were seen only in the p

134 results indicate that C-H hydroxylation and desaturation follow analogous stepwise reaction channels

135 ) had at least 3 desaturations, 12 (10%) had desaturation for more than 10% of the monitored time, an

136 xD3 and MsexD5 biosynthesize 3UFAs via E/Z14 desaturation from diunsaturated fatty acids produced by

137 ity to a chemo- and regioselective substrate desaturation from the C(2)-H group, leading to desaturat

138 adverse procedure-related events and oxygen desaturation, future study is warranted to improve prepr

139 Children with and without desaturations had comparable rates of return for care, w

140 Although temperature regulation of desaturation has been studied at the molecular and bioch

141 red into isolated bradycardia (IB), isolated desaturation (ID) and combined desaturation/bradycardia

142 ly the consequence of reduced membrane lipid desaturation, implicating other mdt-15-regulated process

143 We imaged the process of capillary desaturation in 3D and demonstrated its impacts on the t

144 spectroscopy assessed intraoperative oxygen desaturation in brain and muscle.

145 trimer gallate in particular modified lipid desaturation in C. elegans, revealed by hyperspectral co

146 te modulates lipid deposition and fatty acid desaturation in Caenorhabditis elegans.

147 udies highlight the importance of fatty acid desaturation in cancer growth and provide a novel mechan

148 to link the function of SAD6 with fatty acid desaturation in crown galls, the lipid pattern was analy

149 urther support to the proposed mechanism for desaturation in iron-2OG desaturase enzymes.

150 that heat inhibits both omega-6 and omega-3 desaturation in phosphatidylcholine, leading to a propor

151 heal intubation-associated events and oxygen desaturation in PICU patients.

152 pid 16:1n-7 and FA indexes of elongation and desaturation in relation to lipogenesis.

153 elimination specifically impacts fatty acid desaturation in the endoplasmic reticulum (ER), suggesti

154 ellular metabolism, including for fatty acid desaturation in the endoplasmic reticulum.

155 ssion increased Suc synthesis and fatty acid desaturation in the leaves.

156 m that was not caused by a decrease in lipid desaturation in this extremophile.

157 the terminal reactions, C5 epimerization and desaturation, in simple carbapenem production.

158 he duration and magnitude of cerebral oxygen desaturation increased in the low-trigger group (median

159 Nineteen had SDB (oxygen desaturation index > 5 events/h).

160 Elevated oxygen desaturation index (>/=15 events/hour) and high percenta

161 The serum desaturation index (an indirect measure of SCD) was sign

162 Secondary outcomes included oxygen desaturation index (ODI), apnea-hypopnea index (AHI), su

163 ing moderate-to-severe apnea) and the oxygen desaturation index (ODI; the number of times per hour of

164 index (r = 0.30, p < 0.01) as well as oxygen desaturation index (r = 0.26, p < 0.01).

165 ess was only associated with the mean oxygen desaturation index among the polysomnography parameters

166 hemoglobin level of 6.5-8.5%, and an oxygen desaturation index of 15 or more events per hour to posi

167 tion < 90%, apnea-hypopnea index, and oxygen desaturation index-did not show any significant associat

168 leic acid (14:1 cis-9) concentration and C14 desaturation index.

169 Two desaturation indexes (16:1/16:0 and 18:1/18:0) were used

170 as also observed between obesity and adipose desaturation indexes.

171 rdance between overall and positional oxygen desaturation indices (ODI) and apnea-hypopnea indices (A

172 supporting the assumption that ictal oxygen desaturation is a consequence of hypoventilation.

173 natal effects are minimal; however, maternal desaturation is a possibility and requires one-to-one su

174 r, the temperature responsiveness of omega-6 desaturation is controlled by a separate QTL on chromoso

175 et al. (2017) indicate that increased lipid desaturation is essential to stem-like characteristics i

176 g the MAGIC population suggests that omega-6 desaturation is largely controlled by cis-acting sequenc

177 hesis in plants includes a complex series of desaturation/isomerisation reactions, catalyzed by four

178 10% of the monitored time, and 51 (43%) had desaturations lasting 3 or more minutes continuously.

179 shift, arterial constriction and haemoglobin desaturation, lasting at least an hour.

180 rious adverse event in 498 therapy sessions (desaturation less than 80%).

181 Using a cerebral desaturation level of 55% as a lower safety limit to gui

182 and n-3 fatty acids of higher elongation and desaturation levels, which indicated a greater promotion

183 id metabolism that results in elongation and desaturation lipid products is thought to play a role in

184 Episodes with desaturations < 90% SpO2 were more common with alfentani

185 thorax, pneumomediastinum) and severe oxygen desaturation (< 70%) were recorded prospectively.

186 mesis with/without aspiration) and/or oxygen desaturation (< 80%).

187 A copper-catalyzed desaturation method that is suitable for converting lact

188 ed to those obtained by the state-of-the-art desaturation methods.

189 ng reactivity complementary to that of prior desaturation methods.

190 ting scale), interface displacements, oxygen desaturations, need for ventilator support, and reintuba

191 iency without changing apnoea length, oxygen desaturation, next-day perceived sleepiness and alertnes

192 Conclusion: Oxygen desaturation occurred during sleep in 70% of hepatopulmo

193 We found that central apnea and O2 desaturation occurred when seizures spread to the amygda

194 44.4%; P < 0.001, but no clinically relevant desaturations occurred.

195 ", a biosynthetic process requiring a Delta6 desaturation of 24:5n-3 to 24:6n-3.

196 FAD-dependent enzymes that catalyze the 1,2-desaturation of 3-ketosteroid substrates to initiate deg

197 ith specificity for this acyl group and more desaturation of acyl groups occurring on phosphatidylcho

198 egrees of regioselectivity and yields in the desaturation of alcohols compared to those obtained by t

199 ve visible light-induced Pd-catalyzed remote desaturation of aliphatic alcohols into valuable allylic

200 Desaturation of aliphatic compounds generally proceeds t

201 ompanied by marked arterial constriction and desaturation of cortical haemoglobin.

202 kinetics of DHC accumulation, the enzymatic desaturation of DHCs fulfills the criteria of an oxygen

203 Desaturation of dietary alpha-linolenic acid (ALA) to om

204 xpression of SCT1 dramatically decreases the desaturation of fatty acids and affects phospholipid com

205 nd CrFAD6, likely donating electrons for the desaturation of fatty acids that stabilize monogalactosy

206 ain, protection against oxidative stress, or desaturation of fatty acids.

207 r degradation thereby inducing Rsp5-mediated desaturation of fatty acids.

208 cts upon starvation stress by elongation and desaturation of fatty acyl chains, implying that only th

209 eactions, including 1beta-oxidation and 9,11-desaturation of GAs, but was lacking the 3-oxidation act

210 activities were also observed: i.e. Delta15 desaturation of linoleic acid as well as trans-Delta12 a

211 Fatty acid desaturation of membrane lipids is a strategy for plants

212 lytic method is described for the alpha,beta-desaturation of N-protected lactams to their conjugated

213 The desaturation of NMDARs causes a deficit in hippocampal l

214 3 are synthesized in developing seeds by the desaturation of oleic acid (18:1) esterified on the memb

215 he major activity of these genes was Delta12 desaturation of oleic acid, but unusual activities were

216 at the omega-7 pathway proceeds via Delta(9) desaturation of palmitoyl-ACP followed by elongation of

217 This approach allowed for efficient desaturation of readily available silyl ethers into synt

218 ta(1)-KstD), which catalyzes the C-1 and C-2 desaturation of ring A.

219 rase-1 (SCD1), an enzyme responsible for the desaturation of saturated fatty acids.

220 chemo-, stereo-, and regioselectivity of the desaturation of stearic acid.

221 D activity but instead catalyzed cis-Delta13 desaturation of stearolic acid when expressed in yeast.

222 ase; TcPYS), appeared to catalyze the direct desaturation of the C1-C2 bond in the pentyl side chain

223 the CNS levels of d-serine, which leads to a desaturation of the coagonist binding site of synaptic a

224 from C4 hydroxylation and Delta4 and Delta8 desaturation of the component long-chain bases (LCBs).

225 Desaturation of the ER membrane may serve as an auxiliar

226 ne cluster have been associated with reduced desaturation of the precursor polyunsaturated fatty acid

227 9,11-secoenol ether employing a mercury-free desaturation of the Treibs type, an oxidative bond sciss

228 re may not be complete Ca(2+) saturation and desaturation of the troponin Ca(2+) regulatory sites wit

229 yme into the lipid bilayer, facilitating the desaturation of very-long-chain (VLC) substrates.

230 ocesses as hydroxylations, chlorinations and desaturations of inert, aliphatic C-H bonds.

231 d as well as trans-Delta12 and trans-Delta11 desaturations of stearolic acid (9-octadecynoic acid).

232 hat Ncb5or supplies electrons for fatty acid desaturation, offer new insight into the regulation of a

233 saturase 2 (FADS2) protein to perform Delta6 desaturation on C24 fatty acids in the endoplasmic retic

234 re prescribed 24-hour oxygen, and those with desaturation only during exercise were prescribed oxygen

235 e oxidation of dihydrophenanthrene by either desaturation or hydroxylation pathways.

236 ect to this plane determines which reaction, desaturation or hydroxylation, will occur.

237 nd the desaturation pathway, with all of the desaturation originating via hydrogen abstraction at C3

238 to the active site that help bias substrate desaturation over hydroxylation.

239 ts who had stable COPD with moderate resting desaturation (oxyhemoglobin saturation as measured by pu

240 ation-associated events (p = 0.35) or severe desaturation (p = 0.08).

241 cancer cells to bypass the known fatty acid desaturation pathway that is dependent on stearoyl-CoA d

242 ter to form an alcohol or proceeds along the desaturation pathway via a second H-abstraction to affor

243 om from C-4 (or possibly C-3) initiating the desaturation pathway, followed by a sequential abstracti

244 for both the C-H hydroxylation at C3 and the desaturation pathway, with all of the desaturation origi

245 cells can exploit an alternative fatty acid desaturation pathway.

246 In an effort to elucidate the lipid desaturation pathways in this model alga, a mutant with

247 Thus, only by targeting both desaturation pathways is the in vitro and in vivo prolif

248 ioning of acyl groups between elongation and desaturation pathways.

249 describe the discovery of altered fatty acid desaturation phenotypes associated with mutants of At1g1

250 vulnerability, resulting in saw-tooth oxygen desaturation possibly representing the earliest manifest

251 Hydroxylation and desaturation proceed by means of a short-lived radical t

252 differ from controls in PUFA elongation and desaturation processes.

253 rded C2 (26%) and C3 (43%) hydroxylation and desaturation products (31%).

254 cally reduced amounts of C3 alcohol (8%) and desaturation products (5%), while the radical rearranged

255 saturation from the C(2)-H group, leading to desaturation products efficiently.

256 erevisiae yields mixtures of cis/transDelta8 desaturation products, predominantly as trans isomers.

257 but this radical apparently does not afford desaturation products.

258 f magnitude decrease in De relative to Do as desaturation progressed down to nanoscale films.

259 s of Arabidopsis result primarily from VLCFA desaturation, rather than by elongation of long chain mo

260 flavonol synthase performs a regioselective desaturation reaction as part of the biosynthesis of the

261 Here we report a desaturation reaction of simple, unactivated alkanes tha

262 egioselectivity and stereospecificity of the desaturation reaction.

263 etioplast metabolism by participating in the desaturation reactions of carotenogenesis and in one or

264 rallel pathways of fatty-acid elongation and desaturation reactions, which are followed by sequential

265 requiring 11 oxygen molecules and fatty acid desaturation requiring 1 oxygen molecule per double bond

266 The duration of hemoglobin desaturation (Sa(O2) < 90%) correlated with increased in

267 ivation, de novo FA synthesis (ACACA, FASN), desaturation (SCD, FADS1), triacylglycerol synthesis (AG

268 nasal cannula likely has no effect on severe desaturation, serious complications, apneic time, oxygen

269 ect by replacing the activity of PTOX in the desaturation steps of carotenogenesis.

270 ications, such as respiratory depression and desaturation, still occur and their importance cannot be

271 C18-fatty acyl chains with various levels of desaturation, suggesting a relatively broad ligand speci

272 limitation, although unpredictable transient desaturation suggests that potential subjects should be

273 l mechanism for the regulation of fatty acid desaturation that is based on competition between Ole1p

274 volumes of brine injection, facilitating the desaturation that leads to decreased trapping relative t

275 OPD and resting or exercise-induced moderate desaturation, the prescription of long-term supplemental

276 ximetry was performed to evaluate a cerebral desaturation threshold to guide the duration of activati

277 tive mechanisms contribute to maintain lipid desaturation through preferential SCD1 regulation and fa

278 During fast simulated VT (300 ms), cerebral desaturation to </=55% occurred in more than half (53%)

279 less for at least 1 minute and 29 (39%) had desaturation to 70% or less for at least 1 minute.

280 infants who had desaturations, 59 (79%) had desaturation to 80% or less for at least 1 minute and 29

281 likely followed by decarboxylation-assisted desaturation to complete isonitrile installation.

282 classical transcript mediates direct Delta4 desaturation to yield 22:6n-3 and 22:5n-6 in human cells

283 nce of fatty acid transformation, especially desaturation, to determination of metabolic fate.

284 pathway interactions in modulating membrane desaturation under temperature stress has been suggested

285 n via 1,5-hydrogen atom transfer (HAT), (ii) desaturation via I(2) complexation, and (iii) vicinal am

286 e examined whether seizure-associated oxygen desaturation was a consequence of hypoventilation and wh

287 Oxygen desaturation was a late phenomenon.

288 Sleep-time desaturation was correlated with clinical variables.

289 The degree of desaturation was significantly correlated with seizure d

290 ents with COPD experiencing exercise-induced desaturation, we evaluated improvements in exercise tole

291 larger, and post-CSD oligemia and hemoglobin desaturation were more severe in FHM1 brains.

292 lemental-oxygen group, patients with resting desaturation were prescribed 24-hour oxygen, and those w

293 lmitoleic and oleic acids (Delta9 fatty acid desaturation) were decreased in TKO relative to wild typ

294 nown to up-regulate fatty acid synthesis and desaturation, which is carried out by the oxygen-consumi

295 functionalities to ultimately effect remote desaturation, while leaving behind a synthetically usefu

296 Among the 62 infants with desaturations who had diary information, 48 (77%) experi

297 e complications, including hypoxemia (oxygen desaturation with Spo2 <=92% for >1 minute).

298 ed as clinically relevant (i.e., true oxygen desaturation with SpO2<89 for >15s) or irrelevant (i.e.,

299 with COPD who have nocturnal arterial oxygen desaturation without qualifying for long-term oxygen the

300 carbon chain to produce an isolated olefin (desaturation) without overoxidation is one of the most i