ライフサイエンスコーパス: desensitize

1 postsynaptic responses when other receptors desensitize.

2 P2X1 receptor function with a propensity to desensitize.

3 2)-based reporters, but cAMP signals did not desensitize.

4 ns are frequent, and some patients cannot be desensitized.

5 DBPCFC without symptoms and were considered desensitized.

6 zation is a mechanism by which receptors are desensitized.

7 rise to two nonconducting states, closed and desensitized.

8 ll allow ions to flow when the receptors are desensitized.

9 Of 138 patients desensitized, 29 (21%) had an immediate and 20 (14%) had

10 ntiplatelet strategy centered on blocking or desensitizing 5-HT2AR to attenuate ADP-mediated alphaIIb

11 from the open (5 seconds) compared with the desensitized (75 seconds) form of the channel.

12 s (Ricinus communis) a novel, allosterically desensitized 910-kD Class-2 PEPC hetero-octameric comple

13 roid allopregnanolone, which was intended to desensitize a fraction of receptors, on a subsequent res

14 The decision to desensitize a patient must always be made on an individu

15 to high-dose VWG OIT, 12 (57.1%) of 21 were desensitized after 1 year (median SCD, 7443 mg of WP; no

16 Such AC inhibition is desensitized after prolonged agonist treatment.

17 Blocking the actions of HMGB1 appears to "desensitize" aged microglia to an immune challenge, ther

18 KK148 is a desensitizing agent, whereas KK150 is devoid of alloster

19 cannabinoid agonists downregulated CB1Rs and desensitized agonist-stimulated [(35)S]GTPgammaS binding

20 To desensitize allergic individuals, subcutaneous injection

21 Sublingual immunotherapy also desensitizes allergic patients to foods-2 major studies

22 d the potency of varenicline to activate and desensitize (alpha4)(3)(beta2)(2) nAChRs in vitro withou

23 -2-95) binds with high affinity and potently desensitizes alpha4beta2 nAChRs.

24 Br-PBTC reactivates desensitized (alpha4beta2)(2)alpha4 nAChRs.

25 sed, blocking (125)I-epibatidine binding and desensitizing alpha4beta2Rs.

26 BKV viremia was observed in 20% of the desensitized and 10% of the non-desensitized (P<0.001) g

27 t-bound/open-pore, agonist-bound/closed-pore/desensitized and antagonist-bound/closed states.

28 sophils, or neutrophils had been depleted or desensitized and in mice in which FcgammaRI, FcgammaRIII

29 s clustering at wound sites, but is promptly desensitized and internalized, which prevents excess con

30 nel blocker [(3)H]tenocyclidine in the nAChR desensitized and resting states with IC50 values of 2 an

31 ts diagnosed in our clinic as AERD that were desensitized and treated with aspirin 300 mg/day between

32 e beta-adrenergic receptors (betaARs) become desensitized and uncoupled from heterotrimeric G protein

33 We also found that the LKB1 complex desensitizes and suppresses myofilament function indepen

34 ical molecules that target this receptor are desensitizing and are essentially S1P(1) functional anta

35 unliganded (closed), glycine-bound (open and desensitized), and allosteric modulator-bound conformati

36 (2) beta (3) gamma (2) receptor in the open, desensitized, and closed/resting state.

37 ed that alpha1A-ARs are less phosphorylated, desensitized, and internalized on exposure to the phenet

38 sequently, the receptors are phosphorylated, desensitized, and internalized.

39 with the resting, antagonist-bound, active, desensitized, and ion-modulated states of the receptor.

40 e functional states, high-pH resting, low-pH desensitized, and toxin-stabilized open, have all been s

41 fter kidney transplantation, compared to one desensitized animal (1/5).

42 Desensitized animals were sacrificed after long-term fol

43 om a desensitized state following removal of desensitizing antigen.

44 veral P2X receptors, including those able to desensitize, are permeable not only to NMDG(+) but also

45 ed by airway afferent nerve stimulation also desensitized at a much slower rate than cough.

46 d nicotine concentration stimulates and then desensitizes autonomic nAChRs leading to disruptions of

47 ee GRK2, and allows it to phosphorylate (and desensitize) beta2ARs, suggesting that the beneficial ef

48 Initially discovered to desensitize betaAR signaling, beta-arrestins are now app

49 Similarly, AT-1001 desensitized both receptor subtypes in a concentration-d

50 ee conformational states (resting, open, and desensitized) but allows for the modulation of the confo

51 esponses both to dynorphin-A and to orexin-A desensitize, but co-application of dynorphin-A and orexi

52 a(2+)channel coupling in dorsal root ganglia desensitized by ARM390 and the rate of resensitization w

53 rom the plasma membrane and are subsequently desensitized by beta-arrestin (beta-arr).

54 ensitivity curves that show a hair bundle is desensitized by efferent stimulation.

55 , indicating that the channels are partially desensitized by extracellular nucleotides.

56 In simple model systems, CB1R is desensitized by GRK phosphorylation at two serine residu

57 AdipoR1 is phosphorylatively modified and desensitized by GRK2 in failing cardiomyocytes, contribu

58 Basophils in whole blood were desensitized by incubation with twofold to 2.5-fold incr

59 responsible for their beneficial actions are desensitized by infection.

60 om rat tail artery and vas deferens are also desensitized by OXY, but not by NE or PE, indicating tha

61 nd alpha2-containing receptors were potently desensitized by the epibatidine analogs.

62 n release of glutamate, synaptic AMPARs were desensitized by transmitter by >90%.

63 ave altered calcium handling, independent of desensitized calcium-contraction coupling.

64 Lastly, downregulation of FNIPs desensitizes cancer cells to Hsp90 inhibitors, whereas F

65 tional omega-6 PUFA-derived endocannabinoids desensitize CB(1) cannabinoid receptors, thus inducing e

66 degradation of endogenous FLS2 may serve to desensitize cells to the same stimulus (homologous desen

67 heightened ATF2 activity also sensitizes or desensitizes cells to ER stress, respectively.

68 Allergen specificity was investigated by desensitizing cells from multi-allergic subjects with gr

69 g (IC50 approximately 0.3 mumol) and acts by desensitizing cells to LPS; it fails to block responses

70 for agonists characteristic of the open- and desensitized-channel conformations results, at least in

71 The structures of resting and desensitized channels reveal a reentrant loop at the ami

72 y of the formyl peptide receptor-1 (FPR1) to desensitize chemokine receptors CCR1 and CCR2.

73 Rgs1 reduces macrophage chemotaxis and desensitizes chemokine receptor signalling.

74 d presence of neurotransmitter, the channels desensitize (close).

75 nd a positive allosteric modulator, and in a desensitized/closed state in complex with fluorowilliard

76 ief stimuli from pH 8.0 to 5.0, whereas they desensitize comparatively slowly to prolonged activation

77 Under desensitizing conditions, the largely decoupled dimer in

78 Transgenic mice with desensitized cones (GNAT2 (cpfl3) line) were used to ide

79 Our results show a proposed desensitized conformation of the LBD dimer is a highly p

80 ure of the GLIC-DHA complex in a potentially desensitized conformation.

81 allosteric modulator 'megabody' and is in a desensitized conformation.

82 channels in both high pH resting and low pH desensitized conformations by single-particle cryo-elect

83 )-value of pH 6.7 and a slow-developing, non-desensitizing current that required a higher proton conc

84 The desensitizing current was abolished by removal of bath s

85 a blocker of ASIC channels, whereas the non-desensitizing current was amiloride insensitive and volt

86 tration-dependent manner: a fast-developing, desensitizing current with an estimated EC(50)-value of

87 gonist concentrations caused monophasic slow desensitizing currents and internalization of receptors

88 r l-DOPA or cocaine, induced adult-like, non-desensitizing D2-autoreceptor responses, selectively in

89 to evaluate the relative abilities of three desensitizing dentifrices to provide rapid relief of den

90 mediated rejection [CMR], 38 no rejection in desensitized [DES] and non-DES control groups) for rever

91 Our findings contributed to the theory of a desensitized dopaminergic system in bulimia nervosa.

92 The desensitizing effect of McTnT1-44 on pCa50 was ablated i

93 ndial glucose homeostasis and 2) the insulin-desensitizing effect of protein ingestion is not due to

94 eceptors, albeit with lower potency and less desensitizing effect.

95 ular responses to allergens, for example, by desensitizing effector cells, inducing regulatory T and

96 function at doses that did not induce S1P(1)-desensitizing effects, such as lymphopenia and lung vasc

97 (alphaP) and is attenuated by mutations that desensitize eIF2B to the inhibitory effect of eIF2(alpha

98 Allergen immunotherapy can desensitize even subjects with potentially lethal allerg

99 2 and KCTD16 homo-oligomers produce strongly desensitizing fast deactivating currents and nondesensit

100 2/KCTD16 hetero-oligomers produce moderately desensitizing fast deactivating K(+) currents, whereas K

101 matic mathematical modeling, demonstrating a desensitizing feedback loop by which OST1-induced upregu

102 ion of postsynaptic AMPARs that contain fast desensitizing flop subunits.

103 otypes and allograft outcomes among patients desensitized for donor-specific antibody (HLA-incompatib

104 levels was evaluated in 13 patients who were desensitized for incompatible renal transplantation.

105 beta-Arrestins desensitize G protein signaling at DA receptors (D1R and

106 ins that are best known for their ability to desensitize G protein-coupled receptors (GPCRs), but als

107 Although the canonical role of GRKs is to desensitize G protein-coupled receptors via phosphorylat

108 regulated by beta-arrestins, which not only desensitize G-protein signalling but also initiate a G-p

109 , and here we show that chronic GIPR agonism desensitizes GIPR activity in primary adipocytes, both d

110 However, CMV disease was common in the desensitized group (3/5).

111 cteristics and outcomes were compared in the desensitized group (N=187) and the non-desensitized grou

112 n the desensitized group (N=187) and the non-desensitized group (N=284).

113 The desensitized group had more lymphocyte depleting inducti

114 The desensitized group had significantly lower baseline leve

115 ceptors (GPCRs) recruit beta-arrestin, which desensitizes heterotrimeric G-protein signalling and pro

116 Intriguingly, FANCJ depletion desensitizes hMSH5-deficient cells to CPT-elicited cell

117 reconfigure how Hsp104 subunits collaborate, desensitize Hsp104 to inhibition, obviate any requiremen

118 r, but it was 10 and 30 times more potent to desensitize human alpha3beta4 receptors than rat alpha3b

119 We adapted a clinical protocol to desensitize human blood basophils ex vivo and investigat

120 Post-KT infections are more common in desensitized ILDKT recipients.

121 been rapidly desensitized with 2.4G2 or mock-desensitized in mice in which monocyte/macrophages, baso

122 sified as severe reactors, were successfully desensitized in the outpatient setting.

123 and reactivates some of these subtypes when desensitized (* indicates the presence of other subunits

124 s of food allergen; it has shown promise for desensitizing individuals with peanut, egg, or milk alle

125 meATP; 10 muM) evoked rapidly activating and desensitizing inward currents (peak 18 +/- 3 pA/pF at -6

126 The 7.6 A structure of a desensitized kainate receptor shows how these changes ac

127 ine mutants to probe the conformation of the desensitized ligand binding domain of functioning AMPAR

128 eby IFN-gamma contributes to host defense by desensitizing macrophages to the immunoregulatory effect

129 Oral immunotherapy (OIT) can successfully desensitize many peanut-allergic subjects, but clinical

130 There is currently no treatment to safely desensitize mast cells to enable robust allergen immunot

131 nstrated the potential of exploiting CD33 to desensitize mast cells to provide a therapeutic window f

132 n has the advantage that it may give time to desensitize mast cells, even in already sensitized indiv

133 gest that reduced degranulation responses in desensitized MCs arise from aberrant actin remodeling, p

134 unctional IgE remains on the cell surface of desensitized MCs following DS.

135 tion with FcepsilonRI impede the capacity of desensitized MCs to evoke the calcium response that is e

136 was still capable of transducing signals in desensitized MCs.

137 icone substrates suppresses fibrogenesis and desensitizes mesenchymal stem cells (MSCs) against subse

138 sessed if the ensuing immune responses could desensitize mice that were sensitized to peanuts.

139 e with mast cells expressing human CD33, and desensitized mice to subsequent allergen challenge for s

140 proach with anti-FcepsilonRIalpha mAb safely desensitizes mice to IgE-mediated anaphylaxis by inducin

141 Overall, blocking HMGB1 "desensitized" microglia in the aged brain, thereby preve

142 However, the Cx26 cKO desensitizes mid-high-frequency DPOAEs and active BM res

143 ts using a cyclic three-state Resting-Active-Desensitized model indicates that the maximal steady-sta

144 e study employs a three-state resting-active-desensitized model to link radioligand binding and elect

145 he framework of a three-state Resting-Active-Desensitized model.

146 d properties of a three-state resting-active-desensitized model.

147 induced refractoriness could be exploited to desensitize MRGPRX2 to prevent severe pseudoallergic rea

148 p.P230S (which is heterozygous with p.R65W) desensitized much faster than wild type receptors and re

149 oxoplasma gondii to discover sensitizing and desensitizing mutations.

150 to agonists, Br-PBTC reactivated short term desensitized nAChRs that have at least two alpha4 subuni

151 required for Br-BPTC to reactivate long term desensitized nAChRs.

152 ch both increases activation and reactivates desensitized nAChRs.

153 neuroprotective gene expression program that desensitizes neurons to glutamate by targeting messenger

154 trations experienced by smokers are known to desensitize nicotinic acetylcholine receptors (nAChRs),

155 ce and transmits an NK-intrinsic signal that desensitizes NK cell responses globally to acute stimula

156 guous information about tilt; by selectively desensitizing one or other of the binocular channels usi

157 ms large-conductance homomeric channels that desensitize only modestly in response to ligand [10].

158 0 allergenic epitopes than subjects who were desensitized only (false discovery rate <= 0.05 and fold

159 ntation Group: (a) High-risk patients (i.e., desensitized or DSA positive/XM negative) should be moni

160 cine/ivermectin complex adopts a potentially desensitized or partially open state.

161 e inhibitor (SSRI) administration to rodents desensitizes or downregulates raphe 5-hydroxytryptamine

162 TGR5 does not interact with beta-arrestins, desensitize, or traffic to endosomes.

163 h frequencies at a physiological pH that may desensitize other receptors.

164 hile the effects of dynorphin-A and orexin-A desensitize over multiple applications, co-application o

165 s subjects with peanut allergy to be rapidly desensitized over as little as 8 weeks of peanut oral im

166 eiving PPOIT and 7.1% receiving placebo were desensitized (P < .001).

167 n 20% of the desensitized and 10% of the non-desensitized (P<0.001) groups by 2 years posttransplant.

168 d offer a novel alternative for difficult to desensitize patients.

169 A subset of highly desensitized patients is at ultra-high risk for infectio

170 ant and posttransplant blood samples from 33 desensitized patients who received alemtuzumab induction

171 Venom immunotherapy is efficient to desensitize people suffering from insect sting allergies

172 es of PIN-specific kinases and phosphatases, desensitize PIN1 to cytokinin.

173 Chronic DiC8 treatment failed to desensitize PKCalpha in several cell types and did not a

174 ing was more stable in the resting than in a desensitized pore conformation.

175 were expressed in locus coeruleus neurons, a desensitizing protocol induced significant internalizati

176 ies of the cyclic three-state resting-active-desensitized (RAD) model.

177 l opens to conduct cations into the cell but desensitizes rapidly.

178 blem in receptor gating: how the resting and desensitized receptor states both display closed ion cha

179 DKaiR1D forms a rapidly activating and desensitizing receptor that is inhibited by both NMDA an

180 Desensitized receptors are thought to be unable to coupl

181 rent is mediated predominantly by conducting desensitized receptors.

182 subunits C and D or A and B) can trap freely desensitizing receptors in a spectrum of states with dif

183 s mainly signal through high-affinity slowly desensitizing receptors to modulate neurons and perform

184 We analyzed 1-year biopsies from desensitized recipients transplanted between 1999 and 20

185 oderately (wIRR = (0.88) 1.35(2.06) ,P = .2) desensitized recipients, with a statistically significan

186 22(3.72) ,P = .002) increased risk in highly desensitized recipients.

187 s with the open probability of the preceding desensitizing response.

188 Throughout the PFC, nicotine strongly desensitized responses to ACh in neurons expressing beta

189 GABA activated slowly desensitizing responses in NG2 cells, which were mimicke

190 suggest that TORC2 is regulated by adaptive, desensitizing responses to stimulatory ligands that are

191 This constitutive activity can desensitize rod photoreceptor cells and lead to night bl

192 eement, low and high BR levels sensitize and desensitize root response to this adverse condition, res

193 imod, conferred minimal renal protection and desensitized S1P(1) These findings demonstrate that sust

194 that the GPCR-arrestin complex initiates non-desensitized signalling at the plasma membrane by coupli

195 d outside of its normal distribution, within desensitized skin and scars.

196 Mature SN DA neurons display prominent, non-desensitizing somatodendritic D2-autoreceptor responses

197 edo nAChRs with higher affinity in the nAChR desensitized state ([(3)H]phencyclidine; IC50 = 4 muM) t

198 nds in the ion channel preferentially in the desensitized state and binds with lower affinity to a si

199 of the kainate receptor GluK2 subtype in its desensitized state by cryo-electron microscopy (cryo-EM)

200 lizes the open state of ELIC relative to the desensitized state by direct binding at specific sites.

201 Human lung mast cells readily recover from a desensitized state following removal of desensitizing an

202 hances the agonist-induced transition to the desensitized state in the prokaryotic channel GLIC.

203 ing activation, these receptors enter into a desensitized state in which the ion channel shuts even t

204 el, identified by photolabeling in the nAChR desensitized state of amino acids within the M2 helices

205 Weak partial agonists that promote a desensitized state of the alpha7 nicotinic acetylcholine

206 at the low absolute free-energy state is the desensitized state of the intact AMPA receptor.

207 channel and alphaM1 was higher in the nAChR-desensitized state than in the resting state and inhibit

208 r GluN2B subunit enter into a nonconducting, desensitized state that can impact synaptic responses an

209 and then transition to an ATP-bound closed, desensitized state that requires an agonist-free washout

210 P2X2 receptors were forced into a prolonged desensitized state upon activation by ATP through a mech

211 tors, we detected the population of a stable desensitized state with a lifetime around 1 s.

212 Without an atomic model for the desensitized state, it is not possible to address a cent

213 es of the receptor, including a model of the desensitized state, showed that barbiturates preferentia

214 In the desensitized state, the LBD undergoes a major rearrangem

215 el 1 resembles a resting state and model 2 a desensitized state, thus providing snapshots of gating t

216 tate and in the previously determined low-pH desensitized state, TM2 is a discontinuous alpha helix i

217 t one electrically intermediate off state, a desensitized state, when ligands remain bound at the lig

218 GSG1L favors the AMPAR desensitized state, where channel closure is facilitated

219 reflects rapid recovery of mast cells from a desensitized state.

220 that memantine stabilizes a Ca(2+)-dependent desensitized state.

221 on reactions during the lifetime of the late desensitized state.

222 on, indicating that it probably stabilizes a desensitized state.

223 at the base of the pore, representative of a desensitized state.

224 onist dissociation and the transition to the desensitized state.

225 ssed channels, enhances the stability of the desensitized state.

226 l structure of GLIC does not correspond to a desensitized state.

227 trinsically occurring closed conformation or desensitized state.

228 ndent gating transitions from the resting to desensitized state.

229 Instead they shift the receptor to a desensitized state.

230 show their ion channels to be closed in the desensitized state.

231 blocker [(3)H]tenocyclidine to nAChRs in the desensitized state.

232 mutations that progressively stabilize deep desensitized states (E713T and Y768R), we were able to s

233 ts suggest stabilization of Ca(2+)-dependent desensitized states as a new strategy for pharmaceutical

234 eases occupancy of GluN1/2A and native NMDAR desensitized states entered after accumulation of intrac

235 conformation that is distinct from open and desensitized states induced by protons.

236 In both the resting and desensitized states of AMPA and kainate receptor subtype

237 tic effects of these ligands, the closed and desensitized states of the GABA(A) receptor gating cycle

238 Ketamine binding decreases occupancy of desensitized states of the GluN1/2B NMDAR subtype.

239 l rearrangements likely correspond to stable desensitized states that are adopted relatively slowly o

240 consisting of nonconducting, conducting, and desensitized states that are starting to become well cha

241 f ionotropic glutamate receptors in putative desensitized states were published.

242 he closed/resting, open/activated and closed/desensitized states, and the mechanism by which conforma

243 ases the duration of bursts and destabilizes desensitized states, resulting in a rapid component of r

244 naive receptors favored a slow transition to desensitized states, whereas occupancy of the third bind

245 he more decoupled states in both resting and desensitized states, which can be correlated with the lo

246 he auxiliary subunit GSG1L in the closed and desensitized states.

247 e closed state to glutamate-bound active and desensitized states.

248 ree energy difference between the active and desensitized states.

249 lix at similar efficiency in the resting and desensitized states.

250 interface conformation in the closed and the desensitized states.

251 nformation is nearly identical in closed and desensitized states.

252 ave similar conformations in the resting and desensitized states.

253 distinct from the resting and longest-lived desensitized states.

254 nate potency and diminishing the ensemble of desensitized states.

255 receptor accumulation in long-lived closed (desensitized) states, suggesting that the observed subty

256 Removing the desensitizing stimulus from the media following desensit

257 overed a variant having the known glyphosate-desensitizing substitution P106L plus three additional o

258 nsgenic rod bipolar cells were more strongly desensitized than control.

259 ht exposure, control rods were more strongly desensitized than transgenic rods.

260 acellular ATP in the Entpd2-knockout animals desensitize the P2X receptors associated with nerve fibe

261 nce indicates that treatment strategies that desensitize the peripheral and central nervous systems a

262 nerating sustained low-amplitude current and desensitize the receptors, thereby reducing the peak amp

263 d ROS generation and Deltapsim loss and thus desensitized the cells to OTA-induced apoptosis.

264 Costimulation with CXCL9 desensitized the chemotaxis of Th1 cells toward CXCL12 b

265 r, we observed that short exposure to 35% O2 desensitized the neurons responsible for ambient O2 sens

266 cells to paclitaxel, and its downregulation desensitized the parental cells.

267 Moreover, SAA1(47-104) desensitized the synergy between intact SAA1alpha and CX

268 Thr(159)/Ser(160) in the Bateman domain that desensitizes the enzyme to allosteric inhibition by GDP/

269 uring the internal dialysis of Cs(+) further desensitizes the photovoltage thereby eliminating its di

270 g thermogenesis, while mutation of this site desensitizes the purine-nucleotide-inhibited state of th

271 sms that include reducing the CNG current by desensitizing the CNG channel via Ca(2+)/calmodulin (CaM

272 ples of fear extinction learning and involve desensitizing the individual to cues that trigger anxiet

273 ) has been used for more than 100 years as a desensitizing therapy for IgE-mediated allergic diseases

274 ing receptor on NK cells and/or T cells, and desensitize these cells.

275 FR-mutated NCI-H1975 and HCC827 cells, TTF-1 desensitized these cells to cisplatin; concomitantly, TT

276 We found that the K15N mutation desensitizes thin filaments to Ca(2+) and slows the kine

277 The cysteinyl leukotriene type I receptors desensitize through negative feedback by protein kinase

278 Our data indicate that Semapimod desensitizes TLR signaling via its effect on the TLR cha

279 ) of 37 SLIT-treated participants were fully desensitized to 10 g of peanut powder, and all 4 achieve

280 bit temporal adaptation, where the system is desensitized to a sustained input.

281 of 23 low-dose VWG OIT-treated subjects were desensitized to an SCD of 7443 mg of WP; 3 (13%) achieve

282 e same patients report clinical benefit when desensitized to aspirin and maintained on daily aspirin

283 owed that calnexin (Canx)-deficient mice are desensitized to experimental autoimmune encephalomyeliti

284 eme iron, in its oxidized state (Fe(3+)), is desensitized to NO and limits cGMP production needed for

285 ave shown that S-nitrosated GC1 (SNO-GC1) is desensitized to NO stimulation following prolonged NO ex

286 Ovalbumin (OVA)-sensitized mice were desensitized to OVA by means of repeated injections of O

287 ss in BM oral immunotherapy (OIT) and become desensitized to UM as well.

288 was found that trans-anethole was capable of desensitizing TRPA1, and unlike allyl isothiocyanate, it

289 ested the hypothesis that capsaicin and heat desensitize TRPV1 through distinct mechanisms involving

290 lation followed by beta-arrestin recruitment desensitized U50,488H-induced ERK1/2 response.

291 or-specific antibody positive, PRA>80%) were desensitized using IVIG and rituximab.

292 way (PD-1?FoxO1?PD-1) that functions to both desensitize virus-specific CTLs to antigen and support t

293 ronic SSRI treatment, 5-HT(1A) autoreceptors desensitize, which allows 5-HT tone elevation.

294 were evaluated in mice that had been rapidly desensitized with 2.4G2 or mock-desensitized in mice in

295 inical outcomes of ABO-incompatible patients desensitized with a nonantigen-specific IA device and ri

296 ho are nonreactive to baked milk (BM) can be desensitized with BM to promote tolerance to unheated mi

297 HC-mismatched donors; four of them were also desensitized with daratumumab and plerixafor (anti-CXCR4

298 Basophils from multi-allergic subjects were desensitized with grass allergen.

299 Patients desensitized with I+R who remain ABMR have long-term gra

300 Twenty highly sensitized patients desensitized with IVIG+rituximab+/-plasma exchange were