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3 in and fibulin-5 mRNAs, increased amounts of desmosine and insoluble elastin, and increased depositio
4 neralized method for an accurate analysis of desmosine and isodesmosine as biomarkers in many types o
5 presence of proteins (such as elastin), and desmosine and isodesmosine cross-linkers in the microcal
6 e measurement of two crosslinking molecules, desmosine and isodesmosine, as biomarkers of elastic tis
7 short repeat, [VPGVG]5, an alanine pentamer, desmosine, and isodesmosine sites with and without gluco
8 well as the elastin cross-linking amino acid desmosine, and that it co-localizes with fibrillin-1-pos
10 protein, FBLN5 and tropoelastin protein, and desmosine content in the vagina suggest that a burst of
16 ction, using a biochemical assay for urinary desmosine (DES), a specific marker for mature elastin de
17 ) to reduce the rate of urinary excretion of desmosine (DES), a specific marker of elastin degradatio
19 ture that is greatly stabilized by extensive desmosine, isodesmosine, and disulfide cross-linkages.
21 somnography, and serum HIF-1alpha, MMP2, and desmosine levels were analyzed using an enzyme-linked im
22 groups were significantly higher, and serum desmosine levels were significantly lower than those in
23 tide of type 1 collagen (ICTP), collagen VI, desmosine, matrix metalloproteinase 2 (MMP-2), tissue in
24 ed bronchiectasis provided blood samples for desmosine measurement, and 381 provided sputum for basel
25 of the alkyl amino acid substitution in the desmosine molecule and is stable toward acid hydrolysis;
28 genous pyridinium derivatives (pyridinoline, desmosine, pyridoxine, pyridoxamine, pyridoxal, pyridoxa
30 berculosis patients compared to controls and desmosine, released during elastin degradation, was 2.4-
34 The enzymatic cross-links pyridinoline and desmosine were examined as candidate sensitizer chromoph
35 IONALE: Sputum neutrophil elastase and serum desmosine, which is a linked marker of endogenous elasti
36 ine the association of elastase activity and desmosine with exacerbations and lung function decline i