1 insulitis and diabetes onset were unabated,
despite a blocked anti-insulin vaccine response in SAP-d
2 Yet,
despite a close resemblance of such activation patterns
3 w HCV prevalence in this large sample of MSM
despite a high prevalence of known risk factors, reflect
4 9, especially in the intensive care setting,
despite a high utilization rate of thromboprophylaxis.
5 ease from these cells for almost two decades
despite a lack of direct evidence.
6 of 14 genes; in contrast, during adulthood,
despite a much larger sample size, only two genes showed
7 to treat coronavirus disease 2019 (COVID-19)
despite a paucity of evidence regarding efficacy.
8 in the cultivated but not wild rubber trees
despite a relatively short domestication history of rubb
9 Racial/ethnic disparity in outcome persists
despite a strictly protocoled targeted temperature manag
10 Despite accruing evidence supporting its benefit followi
11 o cannot complete CSR or affinity maturation
despite accumulating significant mutations in 5'Smu as w
12 ef of withdrawal symptoms and drug cravings,
despite acting on the same opioid receptors triggered by
13 Vaccine failure was defined as TBE
despite adherence to the recommended vaccination schedul
14 Despite advances in diagnosis, smear microscopy insuffic
15 Despite advances in directing the assembly of biomacromo
16 Despite advances in the identification of intermediates,
17 Despite advances in the treatment of diabetes mellitus,
18 Background
Despite advances, blood oxygen level-dependent (BOLD) ca
19 eritoneum, has a long-term survival of < 20%
despite aggressive multimodality treatment.
20 relatively little research in avian systems,
despite ample evidence of their effects in mammalian sys
21 Despite an abundant literature on gold nanoparticles use
22 Despite an increased growth rate, virulence was still de
23 Despite an overall incidence of 19%, there was a signifi
24 Moreover, these benefits are conserved
despite appreciable corticospinal conduction delays.
25 Despite associating with SPEN and chromatin, Xist-2kb di
26 Despite being an essential component of meta-analyses, h
27 Despite being characterized by various experimental tech
28 Despite being constrained to the single-chain precursor
29 Despite being extensively studied, how the Polycomb syst
30 Despite being found diversely in male gametes (e.g., Pla
31 ortion of patients do not respond to therapy
despite being infected with fungi that are susceptible t
32 Despite being prolific innate killers, NK cells are also
33 Ph-like B-ALL) experience high relapse rates
despite best-available conventional chemotherapy.
34 Despite blacks (n = 407) reporting higher levels of medi
35 Despite both control and ACC2 iKO mice exhibiting a simi
36 Despite carbon-carbon (C-C) bonds providing the central
37 Despite certain shortcomings, tele-oncology has great po
38 can extrude a polar body and be fertilised,
despite chaotic chromosome segregation at the first meio
39 AD skin shows a NK-cell dysregulation, which
despite clinical improvement under systemic therapy was
40 Despite complete loss of hair-cell function, tmc triple-
41 acked critical knowledge about COVID-19 and,
despite concern, were not changing routines or plans.
42 h results in a prolonged heat shock response
despite concomitant degradation of the covalent ligand/H
43 Despite conservation of CENH3 function across crops, CEN
44 Despite considerable progress, we are still far from bei
45 rgic stimulation of PFC produced wakefulness
despite continuous exposure to a general anesthetic.
46 Despite convincing evidence on the induction of MDSCs by
47 receptor (C3aR) signaling abrogates disease
despite DAF deficiency, confirming complement dependence
48 ly identify patients at risk remains limited
despite decades of clinical research.
49 d halt species extinctions are not being met
despite decades of conservation action.
50 Despite decades of research on the fate of phenolic comp
51 or HIV infection, as these cells can persist
despite decades of treatment with antiretroviral therapy
52 ormance across nine health state categories,
despite disparate experimental and disease contexts.
53 Despite displaying an epithelial morphology, sEOC mainta
54 ing replication arrest, allowing replication
despite DNA damage.
55 Despite efforts for beta-C-H functionalization in carbon
56 tly than all other macrophages and monocytes
despite equivalent infections through enhanced autophagy
57 ) burden in Kenya is not well characterized,
despite estimates needed to identify future health prior
58 Despite excitement around ProQ as a novel global RNA-bin
59 Despite extensive efforts, we were unable to reproduce t
60 Despite extensive examples that implicate classical comp
61 This maintains normal charged tRNAGln levels
despite Gln4p depletion, confirmed experimentally using
62 Despite growing evidence for intraspecific trait differe
63 Despite growing evidence that repetitive transcranial ma
64 Despite growing research in this area and an increasing
65 anding speech in noise or competing talkers,
despite having "normal" hearing in terms of audiometric
66 Despite having 10% less lignin, CCR2(-/*) line 12 grows
67 Despite having a network of cytoplasmic interconnections
68 rove the physiology of NPC assembly mutants,
despite having only negligible effects when NPC biogenes
69 Despite HF syndrome complexities, evidence of significan
70 Despite high coverage and high adherence to SMC, the inc
71 Yet
despite high infection rates, only a fraction of H. pylo
72 Despite high sequence conservation and structural simila
73 a population intervention for HBV infection,
despite high-profile data supporting its success with hu
74 with cardiogenic shock treated with VA-ECMO,
despite higher complication rates.
75 rvoir of infected CD4+ T cells that persists
despite HIV-specific cytotoxic T cell (CTL) responses.
76 Our results demonstrate that
despite IGPS's classification as a carboxy-lyase (i.e. d
77 ice demonstrated improved glucose tolerance,
despite impaired insulin sensitivity and enhanced pyruva
78 yneuropathy (CIDP) and diabetes is uncertain
despite important diagnostic and management implications
79 Despite impressive outcomes, relapse with CD19(-) diseas
80 high-quality two-dimensional materials, but
despite improvements it is still limited in yield, later
81 induced weight gain and metabolically normal
despite increased food intake, comparable activity, and
82 developmental phenotypes across individuals
despite inevitable biological stochasticity.
83 Despite initially responding to FLT3 inhibitors, most pa
84 understanding of Alzheimer's disease remain
despite intense research efforts.
85 Despite intensive study, plant lysine catabolism beyond
86 ure of this requirement has remained elusive
despite intensive study.
87 Despite involving the same causative allergens, allergy
88 Despite Israel's having been declared polio-free in 1988
89 Despite its asymmetric architecture, the gamma-TuRC arra
90 cooperativity in autophosphorylation of CpxA
despite its asymmetric structures, indicating that these
91 Despite its economic and cultural importance, a high-qua
92 Despite its importance, the molecular mechanisms regulat
93 Despite its known connection with heparanase, a recently
94 Despite its malignant phenotype, the prevalence of TKOS
95 Despite its popularity, chromatin immunoprecipitation fo
96 Despite its prevalence, our mechanistic understanding is
97 Despite its promising activity, bryostatin 1 is neither
98 Despite its relevance as a disease-causing serotype, the
99 Despite its significance, many WAT-related pathophysiogi
100 Despite its success, it does not always provide patients
101 Despite its ubiquitous expression on human NK cells the
102 Despite its ubiquitous use in medicine, and extensive kn
103 Background
Despite known limitations, the decision to operate on ab
104 ter sterile inflammation with silver nitrate
despite levels of Saa1 and Saa2 being comparable to high
105 and 10(-3.78) G(0) (graphene) were measured,
despite limited electronic coupling to the Au electrode,
106 nt Caribbean people avoided close kin unions
despite limited mate pools that reflect small effective
107 Despite long-standing recognition of the importance of p
108 PLWH is low in Europe and the United States,
despite longstanding international recommendations.
109 ouston, TX, USA), with refractory agitation,
despite low-dose haloperidol, were randomly assigned to
110 Diuretic sensitivity in CKD is maintained
despite lower diuretic clearance.
111 sity who did not improve insulin sensitivity
despite marked (~20%) weight loss.
112 Despite marked variation in tissue architecture and rege
113 ve visual field and optic nerve head changes
despite maximal tolerated medical therapy.
114 Despite medical advancements, it's prognosis remains poo
115 Accordingly,
despite mice with conditional deletion of Nf1 in mature
116 Despite more than a century of intense research, therape
117 Despite mounting evidence implicating inflammation in ca
118 Despite mounting evidence suggesting the involvement of
119 Despite multiple gene expression studies becoming availa
120 Despite nearly three decades of advances in the manageme
121 Despite no net change in species richness at the spatial
122 neural progenitors form stereotypic patterns
despite noisy morphogen signaling and large-scale cellul
123 mpathetic neural hyperactivity that persists
despite normalization of LVEF.
124 n evaluating new candidate disease variants,
despite not having been developed specifically for this
125 Despite numerous attempts to elucidate the developmental
126 Despite numerous clinical studies, outcomes are consiste
127 Despite numerous studies examining how CodY controls gen
128 Cs when examined under low-shear conditions,
despite obvious decrement of cellular deformation at mod
129 M delta power is not progressively increased
despite of accumulated sleep loss over days.
130 on of hepatocellular injury in knockout mice
despite ongoing carbon tetrachloride insult, associated
131 er-pressure and initiate a caldera collapse,
despite only modest precursors.
132 if hyperglycemia is inadequately controlled
despite optimal medical treatment for type 2 diabetes.
133 Finally,
despite our best efforts to enhance measurements and IOL
134 hare some strikingly similar characteristics
despite over 300 million years of independent evolution
135 tuberculosis (TB) remain poorly understood,
despite over half a million incident cases worldwide in
136 ntly more patients (72.7% vs 23.1% p = 0.04)
despite overall larger baseline defect size (32.7 +/- 19
137 emale pups exhibit no morbidity or mortality
despite partial X reactivation.
138 t of neonatal seizures has changed minimally
despite poor drug efficacy.
139 Despite pre-clinical data supporting the drug-biomarker
140 Despite prednisolone and cortisol levels commonly being
141 Despite preliminary positive results, a previous study i
142 protect against cerebrovascular dysfunction
despite prolonged obesity.
143 ng patients perceived to be deriving benefit
despite radiographic progression, were randomly assigned
144 ence enables stereotypy in sensory responses
despite random connectivity.
145 Despite recent advances, targeted delivery of therapeuti
146 Despite recent in vivo and in vitro studies supporting t
147 Despite recent progress, it remains challenging to achie
148 Despite recovery program success in saving the species f
149 Despite replicating in the cytoplasm, ZIKV and Dengue vi
150 ly followed by more rapid rebound of T(regs)
Despite robust depletion of host T(conv) and host T(regs
151 Despite several risk factors during childhood predicting
152 using Villin-Cre, female mice remain healthy
despite significant X-autosome dosage imbalance.
153 We found sex-specific response patterns
despite similar behavioral indicators of pair-bond estab
154 r than the GI of the test group (P <= 0.001)
despite similar plaque levels (P = 0.436).
155 Despite similar weight reductions 1 year after surgery (
156 Further, it is demonstrated that,
despite small isobaric interferences, results obtained a
157 in handling the challenge of decoy selection
despite some issues associated with clustering large dec
158 Despite some progress in its prevention, more can be don
159 or non-high-density cholesterol >=100 mg/dl
despite statin therapy.
160 Despite strong transethnic genetic correlations reported
161 Despite such minuscule gradients (which greatly limit th
162 Despite such promise, current physical realizations of m
163 most common intraocular tumour in adults and
despite surgical or radiation treatment of primary tumou
164 was equal or greater than primary infection
despite that a protective adaptive response to UPEC infe
165 Despite the ability to dampen the spread of SARS-CoV-2,
166 Importantly,
despite the absence of catalytic activity, PTPRU binds s
167 Our results showed that viremia rebounded
despite the absence of HIV-1 adaptation to VRC01 and an
168 Despite the abundant presence of HDAC inhibitors such as
169 Despite the apparent destruction of most tumor cells by
170 Despite the availability of new treatment options, initi
171 However,
despite the behavioral data, there is no neurobiological
172 However,
despite the biological and biotechnological importance o
173 Despite the clinical importance of polymyxins and the em
174 Despite the combination of chemometrics and sensors, to
175 Despite the common occurrence of brain injury in patient
176 Despite the correlation between abnormal nuclear shape a
177 Despite the decrease in ZIKV cases since the 2015-2016 e
178 Despite the decreased mitochondrial area, complex III an
179 Despite the demographic differences between the surveill
180 Despite the development of second-generation antiandroge
181 Despite the difficulty in culturing many microbes from a
182 Despite the discovery of acesulfame and PFAS in most OSP
183 Moreover,
despite the disruption of the mitochondrial mitofilin pr
184 Despite the diversity in function, basic insight into th
185 Despite the effectiveness of current medications to trea
186 sing among young adults below screening age,
despite the effectiveness of screening in older populati
187 Despite the effectiveness of this treatment, disease rel
188 Despite the elucidation of the complexoform, it remains
189 Despite the existence of screening programmes worldwide,
190 rated using CRISPR/Cas9 method differentiate
despite the expected derepression of the miRNA targets.
191 Despite the fact that the radical pair is identical in a
192 e is understood about dorsal horn circuitry,
despite the fact that this region loses most of its norm
193 Despite the fact that this reveals a mechanism by which
194 Despite the global scale-up of antiretroviral therapy (A
195 Despite the growing body of evidence, the optimal admini
196 Despite the growing interest in activity-dependent plast
197 Despite the heterogeneity of IBS, patients have signific
198 Paradoxically,
despite the high levels of Env on the surface of MT-4 ce
199 ng that DrBHV-vectored vaccines might invade
despite the highly prevalent wild-type virus.
200 Despite the importance of AKT overactivation in tumor pr
201 Despite the importance of interfacial proteins, comparat
202 Despite the importance of TBR for swallowing performance
203 rmation about the receptor distal N-termini,
despite the importance of the latter in signaling, regul
204 However,
despite the important role of IL-1beta in controlling lo
205 Despite the improved mass resolving power, the measured
206 nhibitor treatment in cancer is not routine,
despite the increasing number of reports of primary infe
207 Despite the key role played by PZA, its mechanisms of ac
208 Overparametrized deep networks predict well,
despite the lack of an explicit complexity control durin
209 o evoke responses in the early visual cortex
despite the lack of direct receptive field activation.
210 ynaptic plasticity, and memory in adulthood,
despite the lack of requirement for neuronal survival.
211 e magnitude of the anisotropy stays the same
despite the large lattice distortion.
212 Despite the large potential for uDCD, programs of this k
213 Despite the loss in Faradaic efficiency, the electrocata
214 Despite the minimal structural differences between recep
215 Despite the more remarkable impact of saturation on O(i)
216 Despite the noisy nature of single cells, multicellular
217 Despite the outstanding clinical results of immune check
218 Despite the overall similar effect sizes of variants in
219 Despite the overwhelming success of vaccines in preventi
220 Despite the pandemic, discard rates across organ has rem
221 Despite the potential role of ER stress for As-induced n
222 Despite the promise of such an approach, previously unre
223 Yet
despite the promising advances of affinity grids over th
224 n the two groups was 255.1 mg per deciliter,
despite the receipt of maximum doses of background lipid
225 Despite the recent approval of tolvaptan, safer and more
226 Despite the relative successes in the surgical treatment
227 h contemporary S-ICD devices and programming
despite the relatively high incidence of comorbidities i
228 Despite the remarkable microbial diversity found within
229 Despite the rise in these disease entities, detailed lon
230 Despite the rising popularity of plant-based alternative
231 Despite the risk of bias, almost all types of interventi
232 ow such a degree of prosociality is possible
despite the risks of exploitation.
233 Despite the routine use of hemodynamic assessment in ped
234 appropriate care to all people with OA, but
despite the scale of the challenge many individuals are
235 Despite the segregation reward, our experiments show tha
236 Despite the sequence homology between acid-sensing ion c
237 Despite the significant medical and economic consequence
238 Despite the significant progress in prediction algorithm
239 Despite the similarity in their enzymatic domain, we fou
240 Despite the structural simplicity, the probe turned out
241 ts exposed to high conditions was maintained
despite the survivorship in both treatments declining in
242 Despite the use of antiretroviral therapy (ART) in HIV-1
243 do not contain a tyrosine-kinase inhibitor,
despite the use of high-risk chemotherapy regimens and f
244 Despite the variety of responses measured in both specie
245 , as the pH decreased from pH 5.0 to pH 4.3,
despite the viscoelasticity of these gels remaining simi
246 Despite the WHO's call for universal drug susceptibility
247 Despite the widespread adoption of organoids as biomimet
248 Despite the widespread application of viral- and non-vir
249 Despite the widespread programmatic implementation of re
250 rol, is often still a considerable challenge
despite their advantageous optical responses and applica
251 Despite their apparent merit, these arguments are flawed
252 s within the obscura group, and asserts that
despite their close relatedness and overlapping ecology,
253 Despite their epidemiological importance, little is know
254 However,
despite their functional importance, the mechanisms cont
255 corticosteroids have recently shown promise,
despite their higher rates of early acute rejection.
256 Yet
despite their hydrological significance, a global synthe
257 Despite their immense contribution in optimizing the pro
258 Despite their importance for neural circuit function, on
259 knowledge on lake fisheries is still limited
despite their importance to food security and livelihood
260 Despite their importance, ADAR RNA substrates have not b
261 Despite their increasing importance, there is currently
262 Despite their intact cGAS sensing pathway, human CD4(+)
263 Despite their negative orientation, internet memes relat
264 they are unable to migrate toward chemokines
despite their normal ability to move randomly.
265 Despite their potential therapeutic relevance, the biosy
266 Despite their relevance for understanding aging and canc
267 highlights their different toxicity pathways
despite their similar structures.
268 Despite these described associations, many cases of fami
269 Despite these effects, BCG vaccination did not increase
270 Maintaining ER lipid homeostasis
despite these fluctuations is crucial to cell function a
271 Remarkably,
despite these functional and behavioral distinctions, al
272 Despite these high systemic ROS levels, stomatal apertur
273 Despite these interventions, confirmed COVID-19 infectio
274 emained discriminatory between RRMS and SPMS
despite these sample-handling variations.
275 Despite this advance, few genetic interactions have been
276 tain good therapeutic relationships is poor,
despite this being a key aspect of the nursing role and
277 Despite this central role in development and evolution,
278 Despite this conservation, we unexpectedly discovered a
279 Despite this dampening, we found no effect of interspeci
280 Despite this evidence, the neural processes that govern
281 Remarkably,
despite this exuberant growth, stable neurotransmission
282 Despite this fundamental split, our current knowledge of
283 Despite this importance, whether NAD(+) capping dynamica
284 Despite this pivotal role, standardization of preclinica
285 Notably,
despite this profound immunodeficiency, mice chronically
286 Despite this, many individuals expressing HLA risk allel
287 Despite this, studying the reassortment process has been
288 Despite this, the genomic events that drive metastatic r
289 ever, the risk of complications still exists
despite transplantation.
290 Despite treatment, the patients with periodontitis had h
291 Despite two decades of study, the full scope of RNAi in
292 This microbial growth occurs
despite unfavourable conditions associated with stone in
293 with meta-analysis for independent studies,
despite using the same data twice in different ways.
294 while fruit-fed bulbuls maintained body mass
despite variation in immune function.
295 Despite whole tissue biopsy studies that have advanced t
296 Despite widespread conversion, roughly 1.2 billion ha of
297 Despite worse outcomes for women with AAA, no studies ha
298 Despite years of significant progress, there is still mu
299 However,
despite years of studies, our knowledge about the protei
300 ver integral prasugrel (6.3+/-11.4; P=0.47),
despite yielding higher prasugrel active metabolite conc