ライフサイエンスコーパス: deuterated

1 With the assistance of reactions using deuterated 1,3-dienes, a proposed mechanism is provided.

2 inverse kinetic isotope effect observed with deuterated 1S, the identification of unprecedented dihyd

3 Notably, deuterated (2)H2-glucose (D2-glucose) labeling studies c

4 measured concentrations of d-25(OH)D(3) and deuterated 24,25-dihydroxyvitamin D(3) at 5 minutes and

5 We administered intravenous, deuterated 25(OH)D(3) (d-25[OH]D(3)) in a pharmacokineti

6 Moreover, incubations of cell lysates with deuterated (2E)-hexadecenal revealed that no hexadecanoi

7 topologue approach using both protonated and deuterated 4,4'-bipyridine molecules demonstrates the si

8 The observation of multiply deuterated 5'-deoxyadenosine and deuterated S-adenosylme

9 When that position in substrate U is deuterated, a primary kinetic isotope effect is observed

10 g cells using a newly synthesized library of deuterated AA isotopologues.

11 ) results in near-quantitative production of deuterated acetamido ester 13a.

12 experimentally by the observation of doubly deuterated acetic acid (CH2DCOOD), when D2O is introduce

13 and anisotropic Raman spectra of acetone and deuterated acetone isolated in an argon matrix have been

14 y, using trimethylphosphine oxide (TMPO) and deuterated acetonitrile as probe molecules, reveal a hom

15 Reactions with deuterated acid display a kinetic isotope effect of 9 +/

16 e analogous alkyl orthoester is treated with deuterated acid, is established utilizing the novel orth

17 These values increase when Calpha-deuterated alanine is used as the substrate.

18 thetic peptides, containing either normal or deuterated alanine residues, were used to confirm the pr

19 dent (2)H quadrupolar splittings from methyl-deuterated alanines and one (15)N amide chemical shift a

20 If deuterated alcohol (EtOD or MeOD) or D2O/deuterated alco

21 If deuterated alcohol (EtOD or MeOD) or D2O/deuterated alcohol is used as an electrospray solvent, t

22 nts for the unusual isotopic distribution in deuterated alkanes.

23 Balances with deuterated and non-deuterated alkyl groups were synthesized, and their intr

24 tron scattering length densities, the use of deuterated alpha-syn versus protiated GCase showed a lar

25 y diverse beta-chiral amines, including beta-deuterated amines, in excellent yields with high enantio

26 Deuterated ammonia is found to react more than three tim

27 -gas through a container filled with aqueous deuterated ammonia reagent (ND3/D2O) and admitting the s

28 he dedeuteration of acetone-d(6) to afford a deuterated ammonium ion.

29 l potassium dihydrogen phosphate and its 70% deuterated analog have been ascertained.

30 NMR spectroscopy studies of a deuterated analog of GMGTPA lipids reveal the presence o

31 tics and detected stabilized trans-DOCO, the deuterated analog of trans-HOCO.

32 Experiments conducted on a deuterated analogous diol derivative confirmed the calcu

33 nt method based on the TAM core CT-03 or its deuterated analogue dCT-03 and trifurcated Newkome-type

34 D mass spectra measured for undeuterated and deuterated analogues and for deprotonated authentic comp

35 The deuterated analogues D(4)-alpha-[Fe(OTf)(2)(mcp)] (D(4)-

36 romethazine, enalapril, and verapamil) using deuterated analogues of these drugs as internal standard

37 After addition of 13C or deuterated analogues to a sediment sample, the isotope d

38 influenced by cofragmentation, especially of deuterated analogues.

39 rther use in synthesis, but also mono- or di-deuterated analogues.

40 ional solid-state NMR spectra on extensively deuterated and (1)H back-exchanged proteins.

41 ase transitions of the deuterated, partially deuterated and hydrogenous organic-inorganic hybrid pero

42 mical calculations as well as examination of deuterated and methylated triradicals provide support fo

43 Balances with deuterated and non-deuterated alkyl groups were synthesi

44 ross-linking strategy, using lysine-specific deuterated and nondeuterated bis(sulfosuccinimidyl)suber

45 Using different combinations of deuterated and proteated acid and hydride reagents, the

46 ior that is intermediate between that of the deuterated and undeuterated perovskite, due to extrinsic

47 samples of a wild-type GPCR (A2AR) that are deuterated apart from (1)H/(13)C NMR probes at isoleucin

48 n previous reports using the AA isotopologue deuterated at carbon 13 (C13).

49 rate that replacing vitamin A with vitamin A deuterated at the carbon 20 position (C20-D3-vitamin A)

50 ane, triphenylgermane, and triphenylstannane deuterated at the heteroatom position have been catalyti

51 states of self-assembled, stereoselectively deuterated benzene-1,3,5-tricarboxamides ((S,S,S)-D-BTAs

52 etralutidine XB acceptor, the association in deuterated benzene/acetone/methanol 70:30:1 at 283 K rea

53 extended for the selective synthesis of C-4 deuterated benzothienopyridines 7u-v and benzofuropyridi

54 enamine then leads to the formation of beta-deuterated bioactive amines with up to 99% deuterium inc

55 t time we show that increasing the number of deuterated bis-allylic carbons to include both C10 and C

56 BS3-d0 is used for the untreated complex and deuterated BS3-d4 is used for the experiment.

57 riment one or more proteins are incubated in deuterated buffer at physiological conditions.

58 ured and then exposed to a flowing stream of deuterated buffer for hydrogen exchange.

59 Kinetic isotope effects from the use of deuterated buffer show that the duplex protects 8-DEA-tC

60 l design for introduction of protein sample, deuterated buffer, and quench buffer.

61 In deuterated buffer, the intermediate becomes labeled, and

62 that is, within a few minutes of exchange in deuterated buffer.

63 escribe the preparation of stereoselectively deuterated building blocks for pharmaceutical research.

64 d OH oxidation of unsubstituted (C10H16) and deuterated (C10H13D3) alpha-pinene are investigated usin

65 In this work, the solution structure of the deuterated Ca(2+)-CIB1 protein complexed with an alphaII

66 y and sensitively indicate the metabolism of deuterated carbon source in microbes.

67 n not only indicate metabolic activity using deuterated carbon sources but also reveal different meta

68 ate, studies examining NADPH production with deuterated carbon sources have failed to account for rou

69 both cis and trans conformers are found for deuterated carboxyl radical DOCO.

70 Moreover, titrations with deuterated carboxylic acid show that the charge on the c

71 nearly with PBAT concentrations dissolved in deuterated chloroform (CDCl(3)), demonstrating accurate

72 The 1H NMR spectra of synthetic 26 in deuterated chloroform and pyridine were identical to tho

73 The signal assignments (in deuterated chloroform) are thoroughly described, identif

74 H NMR signals when the data were acquired in deuterated chloroform.

75 The use of deuterated cholesterol did not show signs of specific in

76 ure cholesterol proximity to M2 while sterol-deuterated cholesterol was used to measure bound-cholest

77 is described for the production of partially deuterated cholesterol which has a neutron scattering le

78 Using deuterated cholesterol, the changes in lipid ordering an

79 uterated (C24:0) fatty acids and selectively deuterated cholesterol, the diffraction data obtained we

80 developments of deuteration, with a focus on deuterated clinical candidates, and highlights both oppo

81 rformed in fully automatic mode and with non-deuterated coffee extracts.

82 d charge recombination with this and the per-deuterated complex (ND(3))(5)Ru(II)(eina)|TiO(2).

83 The pharmacokinetics of a deuterated compound depends on the location(s) of deuter

84 The deuterated compounds d3-androstenone, d3-skatole and d6-

85 Tandem mass spectrometric analyses of deuterated congeners and MS(3) spectra are consistent wi

86 al reaction for a compound with that for its deuterated counterpart, can be substantial(1,3,4).

87 y different Tafel slopes for TEAH(+) and its deuterated counterpart, TEAD(+).

88 ation of classes of compounds in cases where deuterated counterparts are either not available or expe

89 moreover, methods for the addition of their deuterated counterparts typically require special techni

90 ossover experiments with selenide 12 and its deuterated crotyl analogue 27 indicated an intramolecula

91 Fully deuterated cyclohexene and cis-6-nonenal ozonolysis, as

92 Deuterated cyclohexene ozonolysis resulted in a less oxi

93 be performed in aqueous (H(2)O) rather than deuterated (D(2)O) solvents, and we now report a method

94 exciplexes that are either protonated (H) or deuterated (D).

95 ation of intact Chlamydomonas cells with per-deuterated D31-16:0 (palmitic) acid yielded D31-18:0 (st

96 ere repeated where the DPPC acyl chains were deuterated (D62-DPPC), allowing spectral resolution of t

97 driving force in the oxidation of partially deuterated DEK, the 1,2-acyl group migration is observed

98 Deuterated derivative 1b is of interest as an internal s

99 In this paper we report the synthesis of a deuterated derivative of phosphonated trityl radical, pT

100 raordinary low line width of the synthesized deuterated derivative, p1TAM-D (DeltaHpp </= 50 mG, Lore

101 nistration to the mouse, CpdX and one of its deuterated derivatives, CpdX-D3, repress as efficiently

102 tering on protein solubilized in "match-out" deuterated detergent, we have been able to interrogate a

103 ferent [2 + 3] imine cages with the aid of a deuterated dialdehyde molecular building block.

104 tudy the mechanism, we synthesized a pair of deuterated diastereoisomers with a chiral center at the

105 e, and -Cl,-OMe), or with partially or fully deuterated dibenzyl N-(CH2Ph)2 moieties.

106 The (1)H NMR spectra recorded in deuterated dichloromethane indicated the presence of con

107 yl ketone (DTbuK), and a series of partially deuterated diethyl ketones (DEK) is studied in the gas p

108 thylamino)styryl-4H-pyran (DCM) laser dye in deuterated dimethyl sulfoxide and its excited state rela

109 For NMR, deuterated dimyristoylphosphatidylcholine (d54-DMPC) and

110 chain perdeuterated DPPC-d62 or chain methyl deuterated DPPC-d6.

111 g, synthesizing, and developing a successful deuterated drug is far from straightforward, and the tra

112 Deutetrabenazine, a deuterated drug that is promising for the treatment of H

113 optical purity, including examples of chiral deuterated drugs.

114 experiments with deuterated phenylalanine or deuterated (E/Z)-PAOx showed that (E/Z)-PAOx is an inter

115 antiomer is antitumorigenic, whereas the (+)-deuterated enantiomer has little to no effect on tumor g

116 The (-)-deuterated enantiomer is antitumorigenic, whereas the (+

117 Furthermore, the single deuterated enantiomers related to CC-122 exhibit profoun

118 Such deuterated ester products provide intermediates for deut

119 Our screening identified the deuterated ethyl ester of D-TAM (radical 13) to be suita

120 gical substrate acetylene (C2H2) to generate deuterated ethylenes (C2H3D and C2H2D2).

121 stalline samples of protonated and partially deuterated [FeL(2) ][BF(4) ](2) [L = 2,6-di(pyrazol-1-yl

122 s resulting from exposure of filter-adsorbed deuterated fluoranthene to N2O5/NO3/NO2 and that collect

123 ured maps of atmospheric water (H2O) and its deuterated form (HDO) across the martian globe, showing

124 he nonsteroidal compound CpdX as well as its deuterated form CpdX-D3 selectively activate the GR indi

125 tituting the salts used for LC-MS with their deuterated form shifts the mass of PCs by the number of

126 ursors (trimethylpyruvic acid and its methyl-deuterated form) not involved in any metabolic pathway w

127 s small amounts of formaldehyde (CH(2)O) and deuterated formaldehyde (CD(2)O) to efficiently label ng

128 expensive isotopic reagents ((18)O water and deuterated formaldehyde) and requires no postlabeling cl

129 We demonstrate that the use of deuterated formate shifts the mass of PCs and provides a

130 ituting protiated LC-MS additives with their deuterated forms provides a way to distinguish PCs and P

131 rometry assay that distinguishes labeled (d5-deuterated) from endogenous (d0) OT.

132 dial-soup Miller-Urey style experiments with deuterated gases and reagents to compare the spark-disch

133 c clamp, with a primed, constant infusion of deuterated glucose and infusion of 20% dextrose as requi

134 an spectra (SCRS) when Escherichia coli used deuterated glucose and Pseudomonas sp. used deuterated n

135 carbon-deuterium bonds transferred from the deuterated glucose precursor.

136 f deuterated naphthalene compared to that of deuterated glucose was observed, presumably owing to dif

137 peak shifts observed in the THz spectrum of deuterated glycine in heavy water, which allow us to sep

138 NMR spectra of deuterated glycine-2-(13)C revealed interactions between

139 mixtures of racemic mono- and prochiral bis-deuterated glycine-2-(13)C were resolved and well simula

140 ural abundance in glycolate using natural or deuterated glycolate as a substrate.

141 d compared isotope effects using natural and deuterated glycolate in either natural or deuterated sol

142 e that both mono- and few-layer hydrogenated/deuterated graphene can be produced.

143 n of the reaction products (hydrogenated and deuterated graphene) was carried out by thermogravimetri

144 brations, the so-called boson peak, in fully deuterated green fluorescent protein (GFP).

145 The deuterated H-bonded analog, F(8)Cmpd-II(LutD(+)), was al

146 lmethyloxycarbonyl- and trityl-protected, C2-deuterated histidine produces a vibrational-probe-equipp

147 However, after synthesizing a C2-deuterated-histidine-containing peptide, we were able to

148 Using deuterated homologues as internal standards, we observed

149 synthesis of substituted indenes selectively deuterated in position 3, which are rare in literature.

150 Neither of these deuterated intermediate states could otherwise form in H

151 s of cocaine (COC) from brain tissue using a deuterated internal standard (COC-d(3)) combined with wi

152 ent parameters, including comigration with a deuterated internal standard or in silico prediction of

153 In this study, a deuterated internal standard was used to account for the

154 abolites spotted onto a tissue section using deuterated internal standard.

155 xycodone, clozapine, and buspirone and their deuterated internal standards using the matrix 3-nitrobe

156 s of the tissues, and quantified relative to deuterated internal standards.

157 y carrying out measurements with the methoxy-deuterated isotopologue rotor 3-d6.

158 d-fluoride complex, F(-)(H(2)CO(3)), and its deuterated isotopologue, F(-)(D(2)CO(3)), by helium nano

159 yllysergamide (DAM-57), and their respective deuterated isotopologues.

160 amide (DAM-57), an ergot derivative, and its deuterated isotopologues; we also provide theoretical pr

161 The (24R),25(OH)2D3 and added deuterated labeled internal standard (24R),25(OH)2D3-d6

162 ng (13)C kinetic isotope effect experiments, deuterated labeling studies, variable-temperature (1)H N

163 Scattering from the deuterated lambda N was recorded for samples containing

164 reatic clamp and primed constant infusion of deuterated leucine.

165 oaches to simultaneously quantify native and deuterated lipid products, we were able to demonstrate t

166 tion, were identified by specific binding of deuterated liposomes to antibodies directed against amyl

167 sly prepared isotopically labeled protein to deuterated lysates, rendering the biological environment

168 h an approach that combines the synthesis of deuterated materials, optoelectronic properties measurem

169 rved at 262 K or 257 K in the protonated and deuterated materials, respectively.

170 >30%, many microorganisms can grow on fully deuterated media, albeit at reduced rates.

171 precursor obtained from microbial culture in deuterated medium.

172 en the VT (1)H T1 of mestranol 8 and methoxy-deuterated mestranol 8-d3.

173 We present precise measurements of doubly deuterated methane ((12)CH(2)D(2)) in natural methane sa

174 a rapid hydrogen/deuterium (H/D) exchange in deuterated methanol.

175 ugh D9-betaine resulted in the transfer of 1 deuterated methyl group to S-adenosylmethionine.

176 tions with dimethylallyl derivatives bearing deuterated methyl groups at the distal (C3) carbon atom

177 on, the installation of metabolically robust deuterated methyl groups, and tandem ring formation, fur

178 e shape experiments performed on selectively deuterated methyl groups, we probed the 3-fold symmetric

179 (2)H NMR relaxation performed on selectively deuterated methyl groups, we probed the dynamics in the

180 on and subsequent Coulomb explosion of fully deuterated methyl iodide, CD(3)I, irradiated with hard X

181 nthesis were assessed from incorporations of deuterated methyl-D9-choline chloride.

182 on-Optimized Spectroscopy (TROSY) and highly deuterated, methyl-protonated samples to study the 230 k

183 The dynamics of molecular rotors in deuterated MFM-180a-d16 and MFM-181a-d16 were investigat

184 a protonated minimal medium, to a completely deuterated minimal medium.

185 eference points from linear regressions of a deuterated n-alkanes reference system was introduced, pr

186 rational C-D frequency shifts of solubilized deuterated n-hexane confirm that it resides in a dry, oi

187 deuterated glucose and Pseudomonas sp. used deuterated naphthalene as sole carbon sources.

188 A lower lipid conversion rate of deuterated naphthalene compared to that of deuterated gl

189 leukocytes and dried blood spots (DBS) using deuterated natural sulfatide substrate.

190 nd, the primary kinetic isotope effects from deuterated nicotinamide nucleotides confirm that hydride

191 In contrast, the deuterated (OD) carbene analogue showed much reduced 1,2

192 n this nonhuman primate study, we administer deuterated oxytocin intranasally and intravenously to rh

193 urine after a breakfast meal that contained deuterated palmitic acid.

194 ures and structural phase transitions of the deuterated, partially deuterated and hydrogenous organic

195 ted ion drift time distributions (XIDTDs) of deuterated peptic peptides are mobility-matched to corre

196 find, identify, and validate many partially deuterated peptides, elicit the HDX information, and ext

197 decrease in PbI(6) phonon frequencies in the deuterated perovskite lattice.

198 Contrary to the disadvantages of deuterated perovskites, such as shorter recombination li

199 stently favors the enantiomorph containing a deuterated phenyl group over the protio or (13)C version

200 s reaction offers a catalytic route to ortho-deuterated phenylacetic acids and benzoic acids and demo

201 Feeding experiments with deuterated phenylalanine or deuterated (E/Z)-PAOx showed

202 ra and T1 relaxation times obtained from the deuterated phenylalanine side chains in free and HAP-ads

203 Several new thio and deuterated phosphate derivatives were protective in a ca

204 Using deuterated phospholipids, we examined the acceleration o

205 d star-shaped polymers, (2) hydrogenated and deuterated polymers, and (3) block copolymer self-assemb

206 ring and neutron scattering experiments with deuterated polystyrene (dPS) grafted silica and poly(vin

207 Finally, we demonstrated that deuterated polyunsaturated fatty acids, which inhibit li

208 However, using deuterated POPC we could clearly establish that COR15A i

209 and proteated acid and hydride reagents, the deuterated positions on the cyclohexene ring can be cont

210 pound (I-PQS) confirmed as PQS-derived using deuterated PQS.

211 poration using stable isotope labelling with deuterated precursors followed by high resolution NanoSI

212 unlabeled product precedes production of the deuterated product, showing that the methylated species

213 ed using mixed (15)N/(13)C labeling and with deuterated protein, MAS at omegar/2pi = 60 kHz, omega0H/

214 nd amyloid formation are accelerated for the deuterated protein.

215 n to compensate for isotope shift effects in deuterated proteins, COMPASS is far more accurate for la

216 roups provide NMR probes in large, otherwise deuterated proteins.

217 inical trials highlight the potential of the deuterated-PUFA (D-PUFA) drug candidates currently in de

218 methods for preparation of site-selectively deuterated PUFAs require rather long, laborious, and exp

219 pparent PE-water distributions of pyrene and deuterated pyrene (performance reference compound) were

220 s were evaluated by spiking VGO samples with deuterated pyrene.

221 ying a combination of [4-(13)C]erythrose and deuterated pyruvate during growth on deuterium oxide.

222 ty of states (and therefore lifetime) of the deuterated reaction complex compared to the hydrogenated

223 lation of free amino groups in paCOS using a deuterated reagent; (ii) labeling the reducing end with

224 Although commercially available deuterated reagents are generally satisfactory as mechan

225 scale to significantly reduce the number of deuterated reagents used, leading to an overall reductio

226 attainable with the development of synthetic deuterated reference samples.

227 Analysis of the products of deuterated retinol showed a lack of scrambling of a puta

228 ) were observed with 3,3-, 4,4-, and 3,3,4,4-deuterated retinol.

229 To enable detection of (15)N-deuterated RT peptides, the software HDX Workbench was m

230 ubisco form nor the use of solvent D(2)O and deuterated RuBP changed the (16)O/(18)O isotope effect o

231 of multiply deuterated 5'-deoxyadenosine and deuterated S-adenosylmethionine when the reaction is car

232 Using a highly deuterated sample of the proteasome labeled with (13)CH3

233 gle spinning (MAS) NMR has focused on highly deuterated samples, in which only a small number of prot

234 nced charge carrier diffusion lengths in the deuterated samples.

235 stems, such as zeolites, small molecules, or deuterated samples.

236 Raman studies on deuterated solutions point to the important role of sulf

237 Using deuterated solvent and protein, the lauryl maltose neope

238 wever, a slower subunit exchange is noted in deuterated solvent, reflecting the poorer solubility of

239 pable of exchanging up to 90% of solvent for deuterated solvent, with a good recovery and repeatabili

240 nd deuterated glycolate in either natural or deuterated solvent.

241 evaporation and subsequently redissolved in deuterated solvent.

242 at room temperature as well as studies with deuterated solvents confirm the calculations.

243 The reduced usage of expensive deuterated solvents from several hundreds of milliliters

244 , and granular maize starches in regular and deuterated solvents, and structural properties and in vi

245 Nd3+ and Er3+ MCs in the solid state and in deuterated solvents, upon excitation at low energy, are

246 the protons was clarified through the use of deuterated species and confirmed both water as well as d

247 The deuterated species was recovered from the monolayer, dig

248 decay rate of syn-CH3CHOO compared with the deuterated species, giving rise to a significant kinetic

249 ce and wastewater samples; thus the use of a deuterated standard (sucralose-d6) was crucial for preci

250 In this study, deuterated standards 2-hydroxy-1,4-benzoxazin-3-one (HBO

251 Notably, the accuracy of exact deuterated structural analogues was found to vary based

252 The synthetic utility of alpha-deuterated styrenes for accessing deuterium-labeled chir

253 incorporation experiments in the presence of deuterated substrate are consistent with the catalytic i

254 he solvent (pentane or diethyl ether); the 3-deuterated substrate, 3-Ddman, was also investigated as

255 The addition of hydrogen peroxide to a deuterated substrate-enzyme (E-S) complex results in the

256 Experiments with deuterated substrates are also shown here to demonstrate

257 heavy-enzyme KIEs of ~3 on k(cat)/K(M) with deuterated substrates are greater than the product of th

258 Competitive (18)O KIEs measured with deuterated substrates are larger than those measured wit

259 In situ NMR experiments with deuterated substrates show that H2 is formed by a cross-

260 Experiments conducted with deuterated substrates were in accordance with this mecha

261 By harnessing such low-cost and versatile deuterated substrates, Raman-DIP has the potential to pr

262 enzymes and were limited by availability of deuterated substrates.

263 ecular decay rates for selectively and fully deuterated syn methyl-substituted Criegee intermediates

264 IR excitation of selectively deuterated syn-CD3CHOO is shown to result in deuterium a

265 tematic shift in the mass of monomers in the deuterated system is consistent with the decomposition o

266 A total of 14 deuterated TGs were significantly decreased in both eWAT

267 ental investigation of DNA containing methyl-deuterated thymine reveals a large isotope effect establ

268 iPr(2))(2), undergoes reversible cleavage in deuterated toluene to afford two :SnAr(iPr4) radicals in

269 actate isotopomer and HDO production using a deuterated tracer.

270 bservable molecules, the spin isomers of the deuterated trihydrogen cation, ortho-H2D(+) and para-H2D

271 ine (22% as choline-d9, with d9 indicating a deuterated trimethyl amine group) and meeting folate-int

272 in situ by the photochemistry of protium and deuterated triplet 2-formylphenylnitrene isolated in an

273 tool to construct organic luminophores and a deuterated trisubstituted alkene.

274 DHX of deuterated ubiquitin, followed by subsequent quenching a

275 r and thus saturation of the atmosphere with deuterated vapor in the ESI region is achieved.

276 aracterized the IR stretching frequencies of deuterated variants of proline and the corresponding car

277 We also synthesized the partially deuterated versions of the above materials and applied s

278 Deuterated water ((2)H2O) is a label commonly used for s

279 for HDX reactivity in the presence of either deuterated water (D(2)O) or ammonia (ND(3)) within the d

280 ne with deionised water (H(2)O) and one with deuterated water (D(2)O).

281 diography was used to trace the transport of deuterated water (D2O) into roots.

282 Deuterated water (D2O) is frequently used to monitor fat

283 yield higher estimates of proliferation than deuterated water (D2O) labeling studies.

284 Deuterated water (D2O), propylene glycol (PG-d8), and di

285 NaH(13)CO3 solution that is also enriched in deuterated water (the spike).

286 matopoietic transplantation (AHSCT) received deuterated water at biologically relevant time intervals

287 The exchange reaction is conducted in deuterated water catalyzed by Raney nickel, and results

288 gluconeogenesis to EGP was quantitated using deuterated water corrected for transaldolase exchange.

289 lic zinc with HCl in water for H2 and DCl in deuterated water for D2.

290 s are inefficient, which curtails the disk's deuterated water formation and its viability as the sole

291 Hepatic DNL was assessed using the deuterated water method corrected for the potential conf

292 Exposure to deuterated water vapour produced an equivalent deuteride

293 Fasting hepatic DNL was assessed using 2H2O (deuterated water) in 149 nondiabetic men and women and m

294 nine infusion) and longer-term (ingestion of deuterated water) MPS responses, the primary outcome mea

295 d of in vitro OEC photoassembly is higher in deuterated water, D(2)O, compared with H(2)O when chlori

296 To this end, we performed deuterated water-labeling experiments in mice, in which

297 ta(2)H(n) values as revealed by spiking with deuterated water.

298 a crude bacterial cell lysate could also be deuterated without the need for separate purification st

299 imensional IMS-MS datasets (undeuterated and deuterated) without the need for dataset alignment.

300 o compare the spark-discharge products of a "deuterated world" with the standard reaction in the "hyd