ライフサイエンスコーパス: deuterium

1 isotopes, including carbon-14, carbon-13 and deuterium.

2 rated compound depends on the location(s) of deuterium.

3 deuterium labelling, where compounds bearing deuterium ((2)H) atoms at chiral centres are becoming in

4 water or deuterium oxide (D(2) O) comprises deuterium, a hydrogen isotope twice the mass of hydrogen

5 ough astronomical observations of primordial deuterium abundance have reached percent accuracy(3), th

6 and employ PELDOR/DEER distance and 3pESEEM deuterium accessibility measurements to interrogate chan

7 ions and the isotopic labeling of methane by deuterium allow for an unambiguous identification of a c

8 lecule, which can be measured using hydrogen/deuterium and (16)O/(18)O-exchange approaches.

9 we based our study on the quantification of deuterium assimilation from heavy water into single bact

10 t compared to complex carbon substrates, the deuterium assimilation is higher in the presence of simp

11 cing an oxacycle) but can, upon encountering deuterium at the first site, hydroxylate the second site

12 llenging to selectively replace protons with deuterium atoms.

13 ternative diastereoisomer formed by use of a deuterium blocking group.

14 he enrichment and distinct spectra of carbon-deuterium bonds transferred from the deuterated glucose

15 ge uncertainties on the cross-section of the deuterium burning D(p,gamma)(3)He reaction.

16 The strategic replacement of hydrogen with deuterium can affect both the rate of metabolism and the

17 such as plants and mammals hardly survive a deuterium content of >30%, many microorganisms can grow

18 The hydrogen isotopes deuterium (D) and tritium (T) have become essential tool

19 clude methane, ethane, carbon-13 ((13)C) and deuterium (D) isotopes of methane, and several combustio

20 Substitution of protium (H) for deuterium (D) strongly affects biological systems.

21 The fusion of deuterium (D) with tritium (T) is the most promising of

22 e (FFM) and fat mass (FM) were determined by deuterium dilution and expressed as FFM (FFMI) and FM in

23 content measured by DXA, total body water by deuterium dilution, and total body potassium by whole-bo

24 Volume of breast-milk intake via the deuterium dose-to-mother technique over 14 d and analyze

25 Infant milk intake (measured via a deuterium dose-to-mother technique), milk micronutrient

26 he structures of capped HIV-1 leader RNAs by deuterium-edited nuclear magnetic resonance.

27 In addition, our findings revealed that deuterium-enriched exhaled semiheavy water, i.e., HD(16)

28 gonal techniques, such as gas-phase hydrogen/deuterium exchange (gHDX), MS is also capable of probing

29 Using hydrogen/deuterium exchange (H/D exchange), computational modelin

30 Hydrogen/Deuterium Exchange (HDX) coupled with Mass Spectrometry

31 ween each isomer by using gas-phase hydrogen-deuterium exchange (HDX) immediately after DMS separatio

32 Hydrogen-deuterium exchange (HDX) mass spectrometry (MS) and cova

33 Hydrogen/deuterium exchange (HDX) mass spectrometry (MS) has been

34 itration calorimetry (ITC) and NMR, hydrogen-deuterium exchange (HDX) mass spectrometry, and chemoinf

35 Hydrogen-deuterium exchange (HDX), where deuterium in D(2)O repla

36 Here, we present a hydrogen/deuterium exchange (HDX)-mass spectrometric study of wil

37 Using hydrogen-deuterium exchange (HDX)-MS to monitor the dynamics of H

38 Using hydrogen-deuterium exchange (HDX)-MS we show that CRL2 activates

39 Hydrogen-deuterium exchange (HDX-MS) mapped onto a full structura

40 omain and the UVRAG BARA2 domain by hydrogen-deuterium exchange and cryo-EM.

41 Mass spectrometry-based hydrogen-deuterium exchange and cysteine-specific chemical footpr

42 enzymes, while the effects on k(ex)/K(d) for deuterium exchange are expressed mainly as an increase i

43 able region, which is identified by hydrogen-deuterium exchange as the common interface for CD53 and

44 Hydrogen-deuterium exchange combined with mass spectrometry (HDX-

45 ation barrier for wildtype ScOMPDC-catalyzed deuterium exchange compared with decarboxylation, becaus

46 Hydrogen-deuterium exchange coupled to mass spectrometry (HDX-MS)

47 Hydrogen-Deuterium eXchange coupled to Mass Spectrometry (HDX-MS)

48 temperature, and mutation dependent hydrogen-deuterium exchange coupled to mass spectrometry (HDX-MS)

49 Mapping of the binding interface by hydrogen-deuterium exchange coupled to mass spectrometry revealed

50 By combining crystallography, hydrogen-deuterium exchange coupled to MS, and vibrational spectr

51 Furthermore, hydrogen/deuterium exchange coupled with mass spectrometry (HDX-M

52 es, with supporting biochemical and hydrogen-deuterium exchange data.

53 Here, crystal structures, hydrogen-deuterium exchange dynamics, and affinity measurements o

54 molecular dynamics simulations, and hydrogen-deuterium exchange experiments demonstrate that GEM bind

55 aphy, cryo-electron microscopy, and hydrogen-deuterium exchange experiments revealed that GS-6207 tig

56 l exchange saturation transfer, and hydrogen-deuterium exchange experiments show that the variant exi

57 ry (IMS-MS) combined with gas-phase hydrogen-deuterium exchange has been used to characterize novel p

58 of trypsinolysis and the extent of hydrogen-deuterium exchange in local secondary structures of A1 w

59 Although using hydrogen-deuterium exchange kinetics with MS (HDX-MS) to interrog

60 ial scanning calorimetry (DSC), and hydrogen-deuterium exchange mass spectrometry (H/D exchange MS),

61 Hydrogen-deuterium exchange mass spectrometry (HDX MS) has become

62 The approach includes hydrogen-deuterium exchange mass spectrometry (HDX-MS) followed b

63 This interference was confirmed by hydrogen-deuterium exchange mass spectrometry (HDX-MS) in solutio

64 Epitope mapping using hydrogen-deuterium exchange mass spectrometry (HDX-MS) indicates

65 Hydrogen deuterium exchange mass spectrometry (HDX-MS) is a power

66 Hydrogen-deuterium exchange mass spectrometry (HDX-MS) is a power

67 Hydrogen-deuterium exchange mass spectrometry (HDX-MS) is an esta

68 Hydrogen/deuterium exchange mass spectrometry (HDX-MS) is an esta

69 o-electron microscopy (cryo-EM) and hydrogen/deuterium exchange mass spectrometry (HDX-MS) mean that

70 Hydrogen/deuterium exchange mass spectrometry (HDX-MS) of complex

71 First, hydrogen-deuterium exchange mass spectrometry (HDX-MS) of membran

72 We used hydrogen-deuterium exchange mass spectrometry (HDX-MS) to obtain

73 Here, we employ hydrogen-deuterium exchange mass spectrometry (HDX-MS) to reveal

74 first comprehensive application of hydrogen-deuterium exchange mass spectrometry (HDX-MS) to study t

75 ibe an integrated approach of using hydrogen-deuterium exchange mass spectrometry (HDX-MS), chemical

76 een accomplished through the use of hydrogen-deuterium exchange mass spectrometry (HDX-MS).

77 Although solution hydrogen-deuterium exchange mass spectrometry (HDX/MS) is well-es

78 Hydrogen/deuterium exchange mass spectrometry (HDXMS) experimenta

79 Amide hydrogen/deuterium exchange mass spectrometry (HDXMS) of proteins

80 olysis mass spectrometry (LTMS) and hydrogen-deuterium exchange mass spectrometry (HXMS) are applied

81 NMR spectroscopy and hydrogen/deuterium exchange mass spectrometry analysis coupled to

82 Hydrogen-deuterium exchange mass spectrometry and molecular dynam

83 Hydrogen/deuterium exchange mass spectrometry and mutagenesis stu

84 rster resonance energy transfer and hydrogen-deuterium exchange mass spectrometry data with molecular

85 Hydrogen-deuterium exchange mass spectrometry gave insight into t

86 Amide hydrogen-deuterium exchange mass spectrometry is powerful for des

87 Hydrogen-deuterium exchange mass spectrometry shows that ATP bind

88 accelerated molecular dynamics and hydrogen-deuterium exchange mass spectrometry to define the PPARg

89 Hydrogen-deuterium exchange mass spectrometry was used to map the

90 llography, cryoelectron microscopy, hydrogen-deuterium exchange mass spectrometry, and mutational stu

91 in the presence of substrates using hydrogen/deuterium exchange mass spectrometry, complemented by mo

92 imetry, intrinsic fluorescence, and hydrogen-deuterium exchange mass spectrometry, have their limitat

93 nd lipid-binding mechanism, we used hydrogen-deuterium exchange mass spectrometry, lipoprotein recons

94 th mutational and kinetic analyses, hydrogen-deuterium exchange mass spectrometry, molecular dynamic

95 Here we use hydrogen/deuterium exchange mass spectrometry, nuclear magnetic r

96 rein apply three structural probes: hydrogen-deuterium exchange mass spectrometry, room-temperature X

97 ere, we use chemical cross-linking, hydrogen-deuterium exchange mass spectrometry, single-molecule FR

98 omain deletion Rabex5 mutants using hydrogen deuterium exchange mass spectrometry.

99 dichroism, NMR, and backbone amide hydrogen/deuterium exchange measurements as well as molecular dyn

100 Here, we combined hydrogen-deuterium exchange measurements by mass spectrometry and

101 straightforward NMR approach termed hydrogen/deuterium exchange memory (HDXMEM).

102 Hydrogen/deuterium exchange monitored by mass spectrometry (HDX-M

103 Hydrogen/deuterium exchange monitored by mass spectrometry (HDX-M

104 Hydrogen/deuterium exchange monitored by mass spectrometry is a p

105 Hydrogen/deuterium exchange monitored by NMR can be used to map e

106 Hydrogen-deuterium exchange MS (HDX-MS) of p38alpha performed at

107 using a synergistic application of hydrogen-deuterium exchange MS (HDX-MS) with other structural bio

108 lision-induced unfolding (CIU), and hydrogen-deuterium exchange MS (HDX-MS).

109 Hydrogen-deuterium exchange MS analysis confirmed that this confo

110 Hydrogen/deuterium exchange MS experiments indicated that antibod

111 of the Rab5-PI3Kbeta interaction by hydrogen-deuterium exchange MS identified p110beta peptides that

112 Three MS-based methods (hydrogen/deuterium exchange MS kinetics; protein-ligand interacti

113 Hydrogen-deuterium exchange MS revealed that beta-sheets in NHERF

114 Unexpectedly, hydrogen/deuterium exchange MS shows that the E2~Ub-binding regio

115 Therefore, we used hydrogen-deuterium exchange MS to identify potential binding site

116 We used hydrogen-deuterium exchange MS to map the binding interface of th

117 footprinting strategies, including hydrogen/deuterium exchange MS, fast photochemical oxidation of p

118 lts from chemical cross-linking and hydrogen-deuterium exchange MS, revealed that the c.2185G->A DHTK

119 Here, using hydrogen-deuterium exchange MS, size-exclusion chromatography, an

120 size-exclusion chromatography, and hydrogen/deuterium exchange MS, we found that TOMM34 associates w

121 Employing hydrogen-deuterium exchange MS, we identified an MA-MA interface

122 Hydrogen-deuterium exchange MS-mediated interrogation of the intr

123 Synergistic changes in deuterium exchange observed at a distal site but not at

124 A kinetic study of the hydrogen-deuterium exchange reaction of cyclohexanone in aqueous

125 the transition state for the OMPDC-catalyzed deuterium exchange reaction of FUMP is ca. 19 kcal/mol s

126 n, compared with the complex to FUMP for the deuterium exchange reaction.

127 nteraction with the transition state for the deuterium exchange reaction.

128 Hydrogen-deuterium exchange studies showed striking differences i

129 Here, amide hydrogen-deuterium exchange with mass spectrometric analysis (HDX

130 Hydrogen/deuterium exchange with mass spectrometry detection has

131 We then explore the use of hydrogen/deuterium exchange with mass spectrometry to evaluate th

132 d structures were in agreement with hydrogen-deuterium exchange, circular dichroism, surface modifica

133 Here, a combination of hydrogen-deuterium exchange, electron paramagnetic resonance, and

134 Using hydrogen-deuterium exchange, we mapped regions involved in TM-dep

135 Hydrogen deuterium exchange-mass spectrometry (HDX-MS) has emerge

136 Hydrogen/deuterium exchange-mass spectrometry (HDX-MS) mapped GCN

137 In this study, we employed hydrogen-deuterium exchange-mass spectrometry (HDX-MS) to investi

138 Hydrogen-deuterium exchange-mass spectrometry (HDXMS) is a powerf

139 atography coupled with differential hydrogen-deuterium exchange-mass spectrometry experiments (SEC-HD

140 This hydrogen deuterium exchange-MS (HDX-MS) study of functional compl

141 uding small angle X-ray scattering, hydrogen-deuterium exchange-MS, circular dichroism and thermal sh

142 ferent phenomena lead to changes in hydrogen/deuterium exchange.

143 e of NPR4, which we validated using hydrogen-deuterium-exchange mass spectrometry analysis of the ful

144 crystallography, site-directed mutagenesis, deuterium-exchange MS, isothermal titration calorimetry,

145 Using hydrogen/deuterium-exchange MS, we found that the RQ substitution

146 Deuterium experiment suggests that this meta-arylation i

147 We find that substituting deuterium for hydrogen resulted in an 87% decrease in th

148 obtained at 33 backbone amides from hydrogen/deuterium fractionation factors by nuclear magnetic reso

149 ght into possible mechanisms contributing to deuterium fractionation in the interstellar medium.

150 We bombarded a high-purity deuterium gas target(10) with an intense proton beam fro

151 Deuterium (H(dAc)) and cognate protium heroin (H(Ac)) ha

152 gens that can be measured using the hydrogen/deuterium (H/D) exchange approach.

153 trometry (MS) experiments confirmed a proton-deuterium (H/D) exchange at the CH(2).

154 rometry (HRMS) coupled with a rapid hydrogen/deuterium (H/D) exchange in deuterated methanol.

155 Purpose To evaluate the use of deuterium (hydrogen 2 [(2)H]) MR spectroscopic imaging f

156 Conclusion Rapidly acquired deuterium (hydrogen 2) MR spectroscopic images can provi

157 s of proton diffusion inside HaPs, following deuterium-hydrogen exchange and migration in MAPbI(3) ,

158 ation performance that combines an excellent deuterium/hydrogen selectivity (8.0) with a high deuteri

159 (M(-1) s(-1)) are reported for exchange for deuterium in D(2)O of the C-6 hydrogen of 5-fluororotidi

160 Hydrogen-deuterium exchange (HDX), where deuterium in D(2)O replaces hydrogen of the backbone ami

161 re larger at lower temperature and also with deuterium in the hydrogen bond.

162 f chiral deuterium-labelled amines with high deuterium incorporation and optical purity, including ex

163 hallenging functional group due to difficult deuterium incorporation and unavailability of precursor

164 Although methods are available for deuterium incorporation at both early and late stages of

165 ex, "forked" pathway, which was confirmed by deuterium incorporation experiments.

166 c glucose production (HGP), gluconeogenesis (deuterium incorporation from body water into glucose), h

167 tein dynamics by measuring the time-resolved deuterium incorporation into a protein incubated in D(2)

168 Comparison of deuterium incorporation profiles revealed asymmetry betw

169 as key to ensuring chemoselectivity and high deuterium incorporation under neutral conditions without

170 nzene to cyclohexene with varying degrees of deuterium incorporation, via binding to a tungsten compl

171 a-deuterated bioactive amines with up to 99% deuterium incorporation.

172 been considerable interest in incorporating deuterium into drug molecules(1).

173 g carbon, silicon, nitrogen, phosphorus, and deuterium into NOM are discussed.

174 eaction, which leads to the incorporation of deuterium into the ortho positions of 4-AP, where the so

175 the light elements produced during BBN(1,2), deuterium is an excellent indicator of cosmological para

176 The use of deuterium is even broader, offering the opportunity to l

177 tered boosters, and discover compounds where deuterium is the basis for the mechanism of action.

178 ortho positions of 4-AP, where the source of deuterium is the solvent, methanol- d(4).

179 With TEMPOH as sacrificial H atom donor, a deuterium isotope effect is observed (k(H)/k(D) = 3.5),

180 d to explore the active site topography; and deuterium isotope effects on the hydrogen atom abstracti

181 ingle-cell Raman biotechnology combined with deuterium isotope probing (Raman-DIP) have been applied

182 this study, we applied Raman microscopy and deuterium isotope probing (Raman-DIP) to detect metaboli

183 ion spectroscopy reveal that the hydrogen-to-deuterium isotopic substitution induces an equilibrium i

184 ofiles of H(2)NCHO, H(2)NCO, HNCO, and their deuterium isotopologues, we showed that a dual-cycle con

185 -1) (THF, -80 degrees C); thus, the hydrogen/deuterium kinetic isotope effect (KIE) = 6, consistent w

186 ic insight of cross-coupling was obtained by deuterium kinetic isotope effect studies.

187 The deuterium kinetic isotope effect, which compares the rat

188 hene vs xanthene-(d(2)), large, nonclassical deuterium kinetic isotope effects are roughly estimated

189 Finally, the deuterium kinetic isotope effects measured suggest that

190 byproduct identification and tracked with a deuterium label.

191 in terms of deuterium uptake to distinguish deuterium labeled and nonlabeled cells.

192 ed classification models could differentiate deuterium labeled and nonlabeled single cells with high

193 vity in the products along with studies with deuterium labeled reactants provide insight into the mec

194 amination of the enantiomerically enriched, deuterium-labeled acetate 1h corroborate C-N bond format

195 Under similar conditions, deuterium-labeled and nonlabeled building blocks showed

196 uding experiments utilizing optically active deuterium-labeled C-H substrates as a model system, shed

197 y of alpha-deuterated styrenes for accessing deuterium-labeled chiral benzylic stereocenters is demon

198 simple and straightforward access to complex deuterium-labeled compounds.

199 Unlabeled and deuterium-labeled dimeric lignin model compounds with be

200 and the FDA has recently approved the first deuterium-labeled drug.

201 resolved small-angle neutron scattering of a deuterium-labeled GFPssrA substrate and an unlabeled arc

202 g microscopy with metabolic incorporation of deuterium-labeled glucose.

203 Omnivores and vegans/vegetarians ingested deuterium-labeled l-carnitine (d3-l-carnitine) or gammaB

204 Here, we used a deuterium-labeled lipoprotein substrate with reconstitut

205 mic solid state (2)H NMR measurements, using deuterium-labeled materials, we proved that the geometry

206 ient o-quinone methide allowed access to the deuterium-labeled o-tert-butylphenol moiety.

207 We used deuterium-labeled POPC-d(31) and DPPC-d(62),separately t

208 g azide bond, (13)C-edited carbonyl bond and deuterium-labeled probes to interrogate various metaboli

209 polar echo (2)H NMR line-shape analysis of a deuterium-labeled sample between 198 and 298 K, which re

210 o probe nonlinear effects, the reactivity of deuterium-labeled substrates, and control experiments re

211 Precisely controlled deuterium labeling at specific sites of N-alkyl drugs is

212 reaction studies, a Hammett analysis, and a deuterium labeling experiment.

213 Deuterium labeling experiments and a comprehensive compu

214 Deuterium labeling experiments and stoichiometric studie

215 Kinetic and deuterium labeling experiments suggested that the alipha

216 yclometalation of chelate aryl substituents, deuterium labeling experiments were consistent with unim

217 ry mechanistic studies, control experiments, deuterium labeling experiments, and kinetic studies have

218 etic acid was suggested and supported by the deuterium labeling experiments, competitive experiments,

219 stic studies, including defined Ni catalyst, deuterium labeling experiments, quantitative determinati

220 r magnetic resonance, mass spectrometry, and deuterium labeling experiments.

221 can be practically used for highly efficient deuterium labeling of solids.

222 tion mechanism was proposed and supported by deuterium labeling studies and isolation of a rhodacycle

223 Deuterium labeling studies established homolytic H(2) (o

224 Deuterium labeling studies established that the key step

225 Deuterium labeling studies suggest O-alkylated cation 16

226 Deuterium labeling studies suggest that formation of the

227 A few control experiments and deuterium labeling studies were carried out to understan

228 g isolation of key metalacycle intermediate, deuterium labeling studies, and DFT calculations were pe

229 atalyst resting state, kinetic measurements, deuterium labeling studies, and DFT computations were co

230 ction reversibility, luminescence quenching, deuterium labeling studies, and quantum yield measuremen

231 sm was supported by competition experiments, deuterium labeling studies, and radical scavenger experi

232 uer and infrared spectroscopic measurements, deuterium labeling studies, natural abundance (13)C KIE

233 Deuterium labeling studies, reaction progress kinetic an

234 termediate was proposed and supported by the deuterium labeling studies.

235 The deuterium labeling study clearly reveals that, in the re

236 HDX changes for such amides require shorter deuterium labeling times (subsecond) than can be perform

237 inary mechanistic studies using an IR probe, deuterium labeling, and kinetic experiments established

238 Control experiments, deuterium labeling, and kinetic studies have been carrie

239 Using a combination of kinetic analysis, deuterium labeling, and reactivity studies as well as in

240 y characterized by tandem mass spectrometry, deuterium labeling, and UV/Vis action spectroscopy.

241 investigations including radical inhibition, deuterium labeling, fluorescence quenching, cyclic volta

242 reliminary mechanistic experiments involving deuterium labeling, kinetic, catalytic, and stoichiometr

243 en investigated through control experiments, deuterium labeling, radical clock, electron paramagnetic

244 Selectivity on model substrates and deuterium-labeling experiments imply that the m-chlorobe

245 defined Ni-H species as well as a series of deuterium-labeling experiments were performed.

246 n was investigated by quenching experiments, deuterium-labeling experiments, and DFT calculations, su

247 vestigation of various substrates as well as deuterium-labeling experiments.

248 Deuterium-labeling studies established reversible 2,1-in

249 Deuterium-labeling studies with 1,1-diboryl alkenes supp

250 Detailed deuterium-labeling studies, together with DFT computatio

251 y mechanistic experiments involving kinetic, deuterium-labeling, and NMR experiments were performed.

252 The deuterium labelled d(3)-acrylamide was used as an intern

253 It is further shown that deuterium labelled MK-7 can be used as an internal stand

254 ethod was applied to the synthesis of chiral deuterium-labelled amines with high deuterium incorporat

255 exchanged-label turnover MRS, only requires deuterium-labelled glucose and standard magnetic resonan

256 Deuterium labelling studies and control experiments enab

257 c resonance spectroscopy in combination with deuterium labelling, we show that the dissociation of a

258 metric catalysis are arising in the field of deuterium labelling, where compounds bearing deuterium (

259 atalytic mechanism was studied by performing deuterium-labelling experiments, which indicated that th

260 nism has been elucidated through a series of deuterium-labelling-controlled experiments.

261 migration, which causes randomization of the deuterium labels along the peptide (hydrogen scrambling)

262 ns; normally the substitution of hydrogen by deuterium leads to a slower reaction.

263 thod for the determination of single-residue deuterium levels in H/D exchange tandem mass spectrometr

264 production of lactate isotopomers was due to deuterium loss during glycolysis.

265 Deuterium mass balance of [(2)H(7)]glucose uptake to (2)

266 reduce or even avoid intramolecular hydrogen/deuterium migration, which causes randomization of the d

267 on spin-echo (NSE) spectroscopy, solid-state deuterium NMR ((2)H NMR) spectroscopy, and molecular dyn

268 le isotopes into the cross-linker (primarily deuterium) or metabolic labeling with SILAC.

269 We used deuterium oxide ((2) H(2) O) labeling and chronic low-fr

270 ed legumes, obtained by watering plants with deuterium oxide (2H2O), were administered in a plateau f

271 nd mung bean were intrinsically labeled with deuterium oxide (2H2O), whereas egg was labeled through

272 Heavy water or deuterium oxide (D(2) O) comprises deuterium, a hydrogen

273 IHN hydrolysis lifetime to less than 10 s in deuterium oxide (D(2)O) at 298 K, whereas the 4,3-IHN is

274 substance into the biofluid sample, such as deuterium oxide (D(2)O).

275 Deuterium oxide was administered throughout the interven

276 ing oxidized boron states in the presence of deuterium plasmas and corroborate empirical findings.

277 s method has been extensively tested using a deuterium/protium system, and substantial improvements i

278 mechanism was investigated experimentally by deuterium quenching and rationalized by density function

279 rent from the Pd(0) pathway, as evident from deuterium scrambling studies that could reveal different

280 With benzene-d(6) as the deuterium source, easily reducible functional groups suc

281 etween fluorobenzene and C(6)D(6) or D(2) as deuterium sources with excellent productivity (TON up to

282 occurs after isentropic compression of fluid deuterium through the first-order insulator-metal transi

283 the mantle source of this water by measuring deuterium-to-hydrogen ratios in these melt inclusions an

284 y predict the results of implosions of solid deuterium-tritium targets carried out with the 30-kilojo

285 erium/hydrogen selectivity (8.0) with a high deuterium uptake (4.7 millimoles per gram).

286 n in the gas phase it is possible to measure deuterium uptake at single-residue resolution.

287 interlaboratory comparison project evaluated deuterium uptake data from the Fab fragment of NISTmAb r

288 he extracellular loops (ECLs) showed reduced deuterium uptake in the pre-hydrolytic state, consistent

289 reproducibility of back-exchange corrected, deuterium uptake measurements for the 15 laboratories is

290 (6.5 +/- 0.6) % for back-exchange corrected, deuterium uptake measurements.

291 cific information is employed to monitor the deuterium uptake of metabolically active bacteria during

292 sheets in NHERF1's PDZ2 domain display lower deuterium uptake than those in the structurally similar

293 ceeds the information derived from an entire deuterium uptake time course by the traditional method.

294 nges in establishing a threshold in terms of deuterium uptake to distinguish deuterium labeled and no

295 In particular, mass shifts caused by deuterium uptake were used (1) to confirm molecular iden

296 ted the reliability of the quantification of deuterium uptake, a well-known indicator for the general

297 carbon source and bacterial identity on the deuterium uptake.

298 Moreover, selective incorporation of deuterium was achieved in the case of 1,3-diynes and 1,3

299 itially labeling the Salmonella strains with deuterium, we employed reverse labeling to track their m

300 e drug substance contains an isotope such as deuterium, which has a natural abundance of only ~0.016%