ライフサイエンスコーパス: develop

1 r resistance to TAM and aromatase inhibitors develops.

2 compatible with this inactivation method was developed.

3 lly available antiviral drugs have yet to be developed.

4 ches from a design perspective is critically developed.

5 oxidase (PAO) activities in milk samples was developed.

6 bicyclic 2-pyridones as peptidomimetics was developed.

7 itive, and reliable fluoride sensor was then developed.

8 ll-molecule ERK5 kinase inhibitors have been developed.

9 sure to modulate the structure of a recently developed 2D perovskite (HA)(2) (GA)Pb(2) I(7) (HA=n-hex

10 Here, we develop 3D printed bionic corals capable of growing micr

11 er pipeline improvement by the community, we develop a benchmark pipeline for inference of cell-type

12 We used the discrete element method to develop a computational model of a deformable cell that

13 Here we develop a consistent metabolic approach that combines tw

14 elicited an equally rapid response aiming to develop a COVID-19 vaccine.

15 Here, we develop a dCas9/CRISPR-based system that allows ectopic

16 initial and confirmatory tests as needed to develop a final assessment of true GFR.

17 We used this process to develop a framework that can be applied in other jurisdi

18 Our aim was to develop a framework that will distill the currently know

19 gely spared from respiratory illness but can develop a life-threatening multisystem inflammatory synd

20 nalysis on a large ovarian tumour cohort and develop a machine learning approach to molecularly class

21 Here we develop a mathematical model to show, that in highly var

22 al and theoretical studies have attempted to develop a mechanistic understanding for the observed beh

23 using deep whole-genome sequencing (WGS) and develop a model that identifies patients with long survi

24 The goal of this work was to develop a multilayered nanoparticle (NP)-electrospun fib

25 aracteristics of insect olfactory systems to develop a new paradigm for quantifying complex odors.

26 Here we develop a non-invasive method to track spatial oxygen di

27 I data and neuropsychological assessments to develop a novel computational phenotyping method that gr

28 failures due to an adverse environment, and develop a pair approximation analysis taking into accoun

29 We develop a pipeline, Antibody Sequence Analysis Pipeline

30 lyses of T cell receptor sequencing data, we develop a quantitative theory of human T cell dynamics c

31 Fs from the TCGA Mutect2 caller were used to develop a solution to merge SNV to MNV.

32 We develop a technique, named MNase hypersensitivity sequen

33 To fill this critical gap, we developed a 2D implementation of the Regional Ocean Mode

34 We recently developed a brain-permeable EP2 antagonist 1 (TG6-10-1),

35 ice deficient in the Ace2 gene (Ace2(-/-) ), developed a cloudy cornea phenotype as they aged.

36 Furthermore, with CLASSED we developed a context-specific model of beta-adrenergic ca

37 Here, we developed a CRISPR-based system for simultaneous quantif

38 ies including additional features of ATI, we developed a final multivariate model with a highly signi

39 ial resolution of cellular force imaging, we developed a force-activatable emitter reporting single-m

40 Bio-Rad Laboratories has developed a fully automated multiplex bead-based assay f

41 Herein we developed a general host-guest strategy to fabricate var

42 We developed a gradient-based unsupervised clustering metho

43 We have developed a greedy algorithm that runs in polynomial tim

44 We developed a hierarchical Bayesian model to estimate popu

45 Here, we developed a machine-learning approach to identify small

46 We developed a mesoscale coarse-grained model to study the

47 In this study, we developed a method, FamANC, that can improve the accurac

48 We developed a miniaturized optoelectronic biosensor using

49 We developed a minimal mathematical model demonstrating gro

50 To assess their affinity to PIPs we have developed a new cell free assay based on the ability of

51 Herein, we have developed a new strategy using proteins as structure-dir

52 We developed a new tracer, an (18)F-labeled difluoro-analog

53 We developed a novel protocol to measure transporter-mediat

54 We developed a nucleotide resolution transcriptome-wide, si

55 Here, we developed a one-stop microfluidic platform to assemble a

56 Here, we developed a piecewise approach for all-atom steered mole

57 om several species of nonmodel treefrogs and developed a pipeline that allowed us to assemble their c

58 We have developed a pipeline that performs maximum likelihood an

59 To address this question, we developed a polymeric-based constructed graft system (CG

60 We developed a purification strategy enabling assaying of i

61 We developed a risk stratification system from known progno

62 Using these polymers, we have developed a series of smart nanocarriers with hierarchic

63 Here, we developed a simple enzyme-linked immunosorbent assay (EL

64 We have developed a specific and sensitive immunosensor for immu

65 ased on the spatio-temporal EEG features, we developed a system for detecting pain perception and rea

66 We have also developed a temperature-based screening method for synth

67 mediated human islet allograft rejection and developed a therapeutic regimen of low-dose recombinant

68 igate the role of IL-31 in IBH of horses and developed a therapeutic vaccine against equine IL-31 (eI

69 nic substrate and a chiral mediator, we have developed a transient-directing-group approach to reduct

70 the highest aMED score category, the risk of developing a kidney stone was between 13% and 41% lower

71 ome missense variants can be informative for developing a more profound understanding of disease path

72 opilina boulardi, they evolved resistance by developing a more reactive cellular immune response.

73 represents the first expert-led process for developing a standardized approach for establishing benc

74 this is achieved, clear potential exists for developing a vastly improved mechanistic understanding o

75 differed between patients who did vs did not develop ACLF and patients who did vs did not die during

76 Here we show that Dysf(-/-) mice develop adverse LV remodeling following I/R injury secon

77 Or does this information processing only develop after many years of experience?

78 Progressive dyspnea on exertion had developed after she returned to the United States.

79 ise ratio, a bioluminescence-based assay was developed against IFN-gamma and provided an optimized, p

80 We have previously developed agents incorporating spiropyran derivatives as

81 metal node, portending a potential avenue to develop an alternative to natural biomarkers.

82 Objective: To develop an approach to identify additional AF-related ge

83 minimizing disruption to host processes, we develop an aqueous-based encapsulation formulation with

84 We develop an Individualized Network-based Co-Mutation (INC

85 Science Translational Medicine, Park et al. develop an oncolytic vaccinia virus that introduces trun

86 Here we have developed an atomistic spin model of elongated magnetite

87 We developed an automated adaptive atlas algorithm to segme

88 To overcome this problem, we have developed an automated and fast fractionation module cou

89 Previously, we developed an efficient method for the simultaneous quant

90 We have developed an extensive framework for the analysis of NGS

91 We recently developed an organotypic slice culture assay for sensiti

92 ctional diversity emphasize the necessity of developing an approach that can fill this space.

93 By developing an experimental setup and analysis tools, we

94 The ultimate goal of developing an integrated molecular classification is to

95 force Diversity office has led the charge to develop and implement evidence-informed interventions to

96 base for methods to support nursing staff to develop and maintain good therapeutic relationships is p

97 from mild COVID-19 to determine whether they develop and sustain multifaceted SARS-CoV-2-specific imm

98 The aim of this study was to develop and test multiclass predictive models for assess

99 ology, hundreds of biotherapeutics have been developed and approved by the US Food and Drug Administr

100 Here, we have developed and extensively characterized a head-specific

101 seekCRIT is developed and tested on Linux CentOS-7.

102 s for measuring human behavior are typically developed and validated for single time-point assessment

103 wever, the mechanisms by which hypermutation develops and whether it predicts the response to immunot

104 tion (HER) in alkaline media is critical for developing anion exchange membrane electrolyzers.

105 ted the incidence rates and hazard ratios of developing aortic aneurysm or dissection among first-deg

106 The study showed how the developed approach can be used to study the heterogeneou

107 ends and possible challenges to this rapidly developing area, with a special focus on the fabrication

108 Antibody-Drug Conjugates (ADCs) developed as a targeted treatment approach to deliver to

109 erall, we indicated this new material may be developed as an anti-bacterial agent for prolonging the

110 d the site of crosslinking, and subsequently developed as reporters in a competitive displacement ass

111 We developed average weighted accuracy (AWA), representing

112 It has been shown that patients with HFpEF develop B-lines upon submaximal exercise stress echocard

113 Predictive algorithms were developed based on logistic regression, random forests,

114 Here we develop bioluminescent circadian reporter mice that are

115 ificant proportion of breast cancer patients develop bone metastases, but the mechanisms regulating t

116 igration time and the increasing size of the developing brain.

117 ting the mitotic surveillance pathway in the developing brain.

118 To address these needs, we developed BrainIAK (brainiak.org), an open-source Python

119 stem cell (iPSC)-derived neurons that model developing brains, we identified thousands of genetic va

120 Postmenopausal women at increased risk of developing breast cancer were recruited and were randoml

121 ice, are highly permissive to SARS-CoV-2 and develop bronchopneumonia and strong inflammatory respons

122 We show that these dendrites develop by retrograde extension, in which the nascent de

123 t regulation and mitigation should always be developed by looking at potential effects from the persp

124 s based on the S-System formalism originally developed by Savageau for analysing biochemical networks

125 Here, we describe the UBPs developed by three research teams and their application

126 monitoring for patients who are unlikely to develop cancer.

127 Patients with severe CRS may develop capillary leak syndrome and disseminated intrava

128 ily, is abundantly expressed in cells of the developing cerebral cortex, including neural progenitor

129 y help identify individuals most at risk for developing chronic PTSD in the aftermath of trauma.

130 For testing M3C, we developed clusterlab, a new method for simulating multiv

131 and to identify individuals at high risk of developing cognitive impairment.

132 Statistically significant risk factors for developing colon pathology include tobacco use (odds rat

133 To develop commercial processes for the production of bulk

134 io fischeri As the juvenile host matures, it develops complex daily rhythms characterized by profound

135 r this disease after menopause and typically develop coronary heart disease several years later than

136 Ecologically, the DIB method developed could determine the variation of TPCs within c

137 re to air pollution, especially in cities in developed countries where air pollution is caused predom

138 s 1290 (758-3719); P < 0.001 and in patients developing CPC vs no-CPC (area under the curve), median

139 be used to identify sea buckthorn cultivars, develop crops and production, and design functional prod

140 To address this, we develop Cyclum, an autoencoder approach identifying circ

141 ding performance suggest great potentials in developing dental restoration with extended service life

142 The developed digital circuit consists of inductors sensitiv

143 arboring P/LP variants who were predicted to develop disease (G+).

144 is finding should be taken into account when developing drugs that modulate BAX activity.

145 This microenvironment develops during the progression of premalignant to malig

146 mice and flies lacking functional autophagy develop early onset progressive neurodegeneration.

147 weeks' gestation predict the overall risk of developing early preeclampsia and indicate distinct subt

148 ill an urgent need to explore these areas to develop effective HIV cure strategies.

149 and large field of view imaging of neurons, developing embryos, and centimeter-scale tissue sections

150 otein expressed mainly in hepatocytes and in developing erythroid cells and is an important focal poi

151 Mice developed expanded germinal center B lymphocyte populati

152 n monkeypox cases from Nigeria, the majority developed fever and self-limiting vesiculopustular skin

153 curs during a relatively short period within developing flowers.

154 Left bundle branch block may also develop following aortic valve disease or cardiac proced

155 -Corey (B-C), van Genuchten, etc.) that were developed for conventional oil and gas reservoirs would

156 he computational framework presented here is developed for RNA hairpin systems, the general method ma

157 il how we and others are applying approaches developed for T2D to the study of heterogeneity in GDM.

158 lulase-linked immunomagnetic methodology was developed for the specific and ultrasensitive analysis o

159 s specific TLR2 signaling processes might be developed for treatment of colonic motility disorders re

160 h lung cancer and was the first EORTC module developed for use in international clinical trials.

161 These sexually committed stages develop from the asexual stages, yet the factors behind

162 gle-molecule super-resolution microscopy has developed from a specialized technique into one of the m

163 Three re-DMEK eyes developed graft failure, all achieving final BCVA <=0.30

164 Using reported measurements, we developed grass functional trait values (physiological,

165 young and middle-aged mice, the latter group developed greater acute axonal and myelin loss attribute

166 in order to protect against diseases and to develop healthy diets.

167 We recently developed high-speed single-point edge-excitation sub-di

168 fect synapse formation and maturation in the developing hippocampus.

169 sentation; of the remaining 886, 126 (14.2%) developed HUS.

170 ended religious services were less likely to develop hypertension.

171 ist colonization by pathogens, and train the developing immune system.(1)(,)(2) However, humans are u

172 Developing improved vaccines that elicit broader immunit

173 r studies indicate that these memory T cells develop in a cell-intrinsic manner following thymic egre

174 to-moderate changes in the ocular adnexa can develop in children and young adults with long-term PGA

175 Most hepatocellular carcinomas (HCCs) develop in patients with chronic hepatitis, which create

176 Dendritic cells (DCs) develop in the bone marrow from haematopoietic progenito

177 Of 1406 skin test-positive contacts, TB developed in 49 (9.8%) of 446 who did not initiate treat

178 Fewer varicosities developed in acutely treated mice while more varicositie

179 Ab depletion studies showed neuritis still developed in the absence of NOD-PerIg CD8(+) T cells but

180 ethodology to evaluate a new diagnostic test developed in the Rapid Diagnostics in Categorizing Acute

181 The method developed in this study permits spatially explicit predi

182 coprevalent TB and 145 (1.9%) adult contacts developed incident TB within 1 year of index patient dia

183 reactive layer of T cells poised to quickly develop into regulatory or effector cells, depending on

184 Meiospores developed into apparently fertile gametophytes, which ga

185 The methodology developed involves two sequential acid treatments follow

186 We developed LeafCutterMD, a new statistical framework that

187 Homozygous mutant mice develop lethal postnatal inflammation of the salivary gl

188 with T-cells co-expressing NOTCH1 and NRARP develop leukemia later than mice transplanted with T-NOT

189 Men developed LVSD more frequently and earlier than women (4

190 Our objective was to develop macaque trophoblast stem cells (TSCs) as an in v

191 how that Sox10 has multiple functions in the developing mammary gland.

192 esentations and used a 3-pronged approach to develop management recommendations based on (1) critical

193 Here, we develop mathematical theory to show that the rate of suc

194 Hereto, there is an urgent unmet need to develop mechanistic treatments directed at root causes o

195 a from a theoretical model, in this paper we develop methods to add signal to real RNA-seq datasets.

196 Eventually, the capability of developed microcarriers for bone tissue formation was ex

197 e swimming in a naturalistic environment and develop models of their action selection across explorat

198 Though the developed models are not a definitive descriptor of O2 c

199 without any ambient PM(2.5) information, the developed models still demonstrated relatively high skil

200 Twenty-four of 44 (55%) patients developed moderate to severe hypophosphataemia (serum ph

201 response, many diagnostic manufacturers have developed molecular assays for SARS-CoV-2 under the Food

202 ide a perspective on the promises of ENS for developing molecular assemblies/processes for functions.

203 Here we have developed monobodies, synthetic binding proteins, that b

204 age-related temporal processing deficits may develop more central to the auditory nerve, possibly due

205 and there have been considerable efforts to develop more selective processes for less constrained su

206 e endogenous opioid system that will help in developing more effective treatments for pain and addict

207 The brains of young songbirds develop motor circuits that achieve the goal of imitatin

208 trolled by diverse NUP98-fusion proteins, we developed mouse models for regulatable expression of NUP

209 we adapted the 3D-bioprinting technology to develop multiple all-inclusive high throughputs and cust

210 hich accounts for both the absolute reliance developing myofibers have on nuclear accrual to establis

211 rmed the superior sensitivity/specificity of developed nanosystem toward rapid identification of ill

212 The metabolic syndrome is prevalent in developed nations and accounts for the largest burden of

213 ortex, including neural progenitor cells and developing neurons.

214 etter identify people at risk for AKI and to develop new approaches to improve AKI outcomes.

215 f native kinetic registration can be used to develop new criteria for comprehensive diagnostics of au

216 < 0.001) compared with patients who did not develop new persistent use.

217 MAPK pathway driving melanogenesis will help develop new treatment approaches targeting this oncogeni

218 pai-conjugated scaffolds is of interest when developing new conducting or electrochromic materials as

219 fective application of signaling kinetics to developing new therapeutics requires reliable kinetic as

220 g pain and itch holds enormous potential for developing new treatments.

221 In this work, we developed NMR chemical shift calculation protocols using

222 w insight into the sequence requirements for developing novel CPPs for transcellular delivery of carg

223 urn out to be of immense consequence towards developing novel point-of-care hematological analyzers f

224 becoming an increasingly important asset in developing novel therapies for cancer.

225 ffect-modeling" approach, wherein a model is developed on RCT data by incorporating a term for treatm

226 te in which there is partial positive charge developing on the C-O carbon atom progressing C-H abstra

227 factors adversely affecting the capacity to develop oral tolerance to food antigen in early life.

228 ning the lapinised vaccine viruses that were developed originally in Korea appears to be more similar

229 n by the human granzyme B promoter (Tax(+)), develop osteolytic tumors.

230 ical setting further underlines the need for developing other technologies, such as phage therapy.

231 after approximately an hour and continues to develop over a period of weeks.

232 Seven patients developed PGD (38.9%), and PGD development was associate

233 ar, non-plaque-forming prion strains instead developed plaques highly enriched in ADAM10-cleaved PrP

234 We validated the previously developed PREDICT scoring tools for stratifying risk of

235 onomous mechanisms alone, but also depend on developing premotor circuits.

236 ced innate-like pathways and characteristics develop progressively in MAIT cells during infection, in

237 to a traumatic event are at greater risk for developing PTSD; highlighting that sleep potentially pla

238 of mortality worldwide, with higher risks to develop pulmonary infections, including Aspergillus infe

239 In total, 61 other patients (52%) developed refractory heart failure to disabling New York

240 Three patients in the RMA group developed relapse.

241 Adults develop respiratory symptoms, which can progress to acut

242 -H functionalization reactions using a newly developed Rh(2) (S-2-Cl-5-CF(3) TPCP)(4) catalyst.

243 With these challenges in mind, we developed RIPTiDe (Reaction Inclusion by Parsimony and T

244 Thus, it will be necessary to develop robust, reliable, and model-based experimental p

245 Our laboratory has developed robust methods that integrate small-peptide un

246 o consider both gain and loss of function to develop safe and effective therapeutic strategies.

247 tients and 2% to 6% of PNH patients go on to develop secondary MDS/AML by 10 years of follow-up.

248 At an optimized condition, the developed sensor exhibits excellent performance in simul

249 ta are available in patients with trauma who develop sepsis.

250 Typically, nePVAC develops signs of exudation over time, causing metamorph

251 stimated 1-year mortality in each condition, developing simple models (and a tool for calculation) of

252 acking PI3Kalpha and PI3Kdelta in Treg cells developed spontaneous peripheral nerve inflammation.

253 The adult K/BxN transgenic mouse develops spontaneous autoimmune arthritis with joint rem

254 equired to assess models of evolution and to develop successful breeding strategies.

255 Nature has developed supramolecular constructs to deliver outstandi

256 decision making at farm and policy level to develop sustainable agriculture in order to minimize env

257 cingly demonstrated the applicability of our developed SWSP sensor as a smart, user-friendly, ultra-l

258 e present at baseline in 120 (60%); 20 (10%) developed symptoms during follow-up of 2.8 +/- 3.0 years

259 stand the heterogeneity of HbF activation by developing techniques to purify and profile differentiat

260 e tension (WDST) based innovative method was developed that can quantify saponin content in aqueous s

261 A multifunctional motile microtrap is developed that is capable of autonomously attracting, tr

262 We develop the contamination mixture method, a method for M

263 committee selected and reviewed the studies, developed the recommendations, and solicited feedback fr

264 RNA secondary structure in miRNA cleavage by developing the new CAP-STRUCTURE-seq method to capture t

265 To explain how these problems develop, the neuroimmune network hypothesis suggests tha

266 ore numerous and complex lymphatic sprouting developing thereafter.

267 To develop this platform, we established a pan-transcriptom

268 We previously addressed this challenge by developing time-shifted mean-segmented Q (tsMSQ) analysi

269 , implementation strategies are important to develop to facilitate decision aid integration for routi

270 Imaging technologies have been developed to address these problems, but each possesses

271 e database, several flexible tools have been developed to aid retrieval and analysis of the data.

272 A Markov model was developed to compare the costs and effectiveness of cabo

273 e centre and telemedicine networks have been developed to coordinate the various service components w

274 ution of the most complete GEM that has been developed to date: the E. coli GEM.

275 have been developed to ensure optimum execution of the stages acro

276 his knowledge, novel diagnostic tools can be developed to guide clinical diagnosis of contact allergi

277 Higher-affinity next-generation ROS1 TKIs developed to have improved intracranial activity and to

278 Machine learning algorithms were developed to identify a combination of antigen- and epit

279 of novel CAR T cell products that are being developed to increase and expand the clinical benefits o

280 Small molecules have been classically developed to inhibit enzyme activity; however, new class

281 A numerical approach has been developed to invert subordination processes and to extra

282 In this study, an integrated approach was developed to map the epitope/paratope of PD-1/nivolumab.

283 An MS-compatible RNA digestion buffer was developed to minimize the number of sample-transfer step

284 sets, which is an emerging method originally developed to permit the sharing of confidential census d

285 uided by biomarkers or clinical-grade assays developed to predict patient response and, ultimately, t

286 and/or specific calpain inhibitors could be developed to prevent cisplatin induced peripheral neurop

287 In preclinical trials, the recently developed tracer 2-methoxy-(18)F-DCFPyL ((18)F-JK-prosta

288 We developed transgenic B. distachyon plants expressing Tnt

289 nutrient deprivation and the information for developing treatment strategies for disc degeneration.

290 Mammalian cells developed two main migration modes.

291 We also developed two structurally similar control compounds, 5

292 A predictive model was developed using density functional theory (DFT) to poten

293 prediction and design corresponding to tools developed using our RNA-As-Graphs (RAG) approach.

294 An underlying Lie algebraic theory is developed using the closure of the algebra to demonstrat

295 ective protocol for the Minisci reaction was developed, using chiral phosphoric acid catalysis.

296 B cell memory, we have not yet succeeded in developing vaccines for some of the world's most deadly

297 The assay was developed with synthetic DNA templates and validated wit

298 ire cold chain storage for global health and developed world long-acting drug delivery applications.

299 g diagnostic groups were compared: typically developing youths (N=693) and youths with DBDs (N=995),

300 of discrete epicardial subpopulations in the developing zebrafish heart.