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2 enic nerve stimulation method allowing early diaphragmatic activation even in deep sedation and, 2) m
11 e lower sternum in association with anterior diaphragmatic and ventral abdominal wall defects suggest
12 transcription factors involved in thoracic, diaphragmatic, and esophageal development or proteins in
14 Prolonged mechanical ventilation results in diaphragmatic atrophy and contractile dysfunction in ani
15 e apocynin-induced attenuation of MV-induced diaphragmatic atrophy and contractile dysfunction occurr
21 lation, pressure support ventilation-induced diaphragmatic atrophy and weakness are associated with b
22 18 hrs of mechanical ventilation results in diaphragmatic atrophy in both laboratory animals and hum
23 the antioxidant Trolox attenuates MV-induced diaphragmatic atrophy independent of alterations in Akt
24 We tested the hypothesis that MV-induced diaphragmatic atrophy is associated with a loss of myonu
25 thesized that mechanical ventilation-induced diaphragmatic atrophy is associated with decreased synth
26 indicate that mechanical ventilation-induced diaphragmatic atrophy is dependent on the activation of
27 revealed that mechanical ventilation-induced diaphragmatic atrophy is due to increased diaphragmatic
31 erlike position, which may potentially lower diaphragmatic attenuation and reduce breathing-related c
32 mechanical ventilation results in decreased diaphragmatic blood flow and induces an oxygen supply-de
33 when subjects inspired using a predominantly diaphragmatic breath at rest (DeltaP(GA) = > 5 cmH(2)O,
34 During the ensuing expiratory phase of a diaphragmatic breath, there was a large resurgence of fe
35 The pattern of modulation during ribcage and diaphragmatic breathing persisted during both mild (peak
38 mechanical ventilation-induced activation of diaphragmatic caspase-3 and inhibition of caspase-3 prev
40 d the capacity to contribute to cells in the diaphragmatic central tendon and lung mesenchyme, indica
43 the PN was paced at 60 beats per minute and diaphragmatic compound motor action potential (CMAP) amp
44 the right PN at 60 per minute and recording diaphragmatic compound motor action potential (CMAP) via
49 us between oxidative stress and the impaired diaphragmatic contractility that develops during MV.
50 ein-1, and tumor necrosis factor-alpha), and diaphragmatic contractility were evaluated after 24 hour
54 hypothesized the occurrence of an expiratory diaphragmatic contraction directed at stabilizing periph
55 expiratory resistances 1) affect expiratory diaphragmatic contraction during spontaneous breathing,
56 ich transvenously stimulates a nerve causing diaphragmatic contraction similar to normal breathing.
62 sence or absence of PH near the level of the diaphragmatic crura was retrospectively established by a
65 ng single-gene knockout mice associated with diaphragmatic defects, rare monogenetic disorders in hum
67 defined as bulbar, upper limb, lower limb or diaphragmatic), diagnosis, functional involvement of a s
68 ry signal was compared with an MR measure of diaphragmatic displacement via a pencil-beam navigator.
69 and causes artifactual defects predicted by diaphragmatic displacement, body mass index, and heart s
73 henomenon, referred to as ventilator-induced diaphragmatic dysfunction (VIDD), is poorly understood.
74 ion support can attenuate ventilator-induced diaphragmatic dysfunction but corresponding human data a
77 anical ventilation is associated with a late diaphragmatic dysfunction related to a structural altera
78 nical ventilation is associated with primary diaphragmatic dysfunction, also termed ventilator-induce
79 insights into the role of open lung biopsy, diaphragmatic dysfunction, and a potential mechanism for
80 fatigue scores, all of which were related to diaphragmatic dysfunction, were significantly higher in
81 ls and humans can lead to ventilator-induced diaphragmatic dysfunction, which includes muscle atrophy
88 post-diaphragmatic re-approximation with sub-diaphragmatic EGJ relocation, and post-sphincter augment
92 extent with lower lung volume, indicating a diaphragmatic electromechanical coupling during spontane
93 e superior vena cava, all patients underwent diaphragmatic electromyographic monitoring using surface
94 each) during incremental cycle exercise with diaphragmatic electromyography (EMGdi) and respiratory p
96 storation of RSA using an hCPG that receives diaphragmatic electromyography input and use it to stimu
97 ons increased respiratory frequency (fR) and diaphragmatic EMG (dEMG) amplitude in relation to the du
98 (2) was higher and intercostal, scalene, and diaphragmatic EMG activity was reduced using NIOV+O(2) c
102 en and men display a comparable magnitude of diaphragmatic fatigue (DF) after work-matched inspirator
105 ssisted mechanical ventilation will preserve diaphragmatic force and prevent overexpression of MAF-bo
107 e ryanodine complex, did reverse the loss of diaphragmatic force associated with mechanical ventilati
108 y, administration of bortezomib improved the diaphragmatic force compared to mechanically ventilated
109 unit pressure, the inspiratory effect of the diaphragmatic force on the lower ribs is equal to the ex
113 function, and few techniques exist to assess diaphragmatic function: the purpose of this study was to
114 halocele (adjusted odds ratio (aOR) = 2.68), diaphragmatic hernia (aOR = 2.58), small intestinal atre
116 uman fetuses with severe isolated congenital diaphragmatic hernia (CDH) and changes in tracheal and a
135 on the highest risk patients with congenital diaphragmatic hernia (CDH), those with agenesis of the d
136 adily identifiable perinatally in congenital diaphragmatic hernia (CDH), where the typical pulmonary
139 used therapy among patients with congenital diaphragmatic hernia (CDH); however, data to support its
141 TM, n=15), tracheal occlusion for congenital diaphragmatic hernia (CDH, n=13), and resection of sacro
142 n and that had severe, left-sided congenital diaphragmatic hernia (liver herniation and a lung-to-hea
143 cholelithiasis (n=2), pyelonephritis (n=2), diaphragmatic hernia (n=1), cecal bascule (n=1), ileus (
144 , $111566 [IQR, $91195-$139936]), congenital diaphragmatic hernia (WIQR, $43948; median, $154730 [IQR
145 ia [n = 6,303], biliary atresia [n = 3,877], diaphragmatic hernia [n = 6,176], gastroschisis [n = 4,8
146 s those with sickle cell disease, congenital diaphragmatic hernia and Eisenmenger syndrome who may be
149 vomiting, diagnosed to have an incarcerated diaphragmatic hernia causing gastric pneumatosis and res
150 performed in prenatally diagnosed congenital diaphragmatic hernia infants (n = 171) born between Nove
154 cians who encounter children with congenital diaphragmatic hernia on either a regular or infrequent b
155 y clinician treating infants with congenital diaphragmatic hernia regarding the latest developments a
156 covered as an incidental finding, late-onset diaphragmatic hernia should be considered a surgical eme
157 ely collected patient data in the Congenital Diaphragmatic Hernia Study Group registry between Januar
158 oreal membrane oxygenation and/or congenital diaphragmatic hernia with an intelligence quotient great
159 agenesis of the corpus callosum, congenital diaphragmatic hernia, facial dysmorphology, ocular anoma
160 ifida, oesophageal atresia, biliary atresia, diaphragmatic hernia, gastroschisis, and Down syndrome w
161 -reduction defects, polydactyly, syndactyly, diaphragmatic hernia, heart defects overall, pulmonary-a
162 urysm, developmental emphysema, inguinal and diaphragmatic hernia, joint laxity, and pectus excavatum
163 wel perforation, bowel resection, congenital diaphragmatic hernia, oesophageal atresia, and ruptured
164 chial arch derivatives, heart malformations, diaphragmatic hernia, renal hypoplasia and ambiguous gen
165 girl 32 days after a repair of a congenital diaphragmatic hernia, with ultrasound signs of acute bow
173 ragm development are the cause of congenital diaphragmatic hernias (CDHs), a common and often lethal
174 Sox7(Deltaex2/+) mice developed retrosternal diaphragmatic hernias located in the anterior muscular p
175 cts, renal agenesis and develop retrosternal diaphragmatic hernias which are covered by a membranous
176 ital anomalies, pyloric stenosis, congenital diaphragmatic hernias, cardiac septal defects, hearing l
177 gous for the dd allele possess communicating diaphragmatic hernias, central tendon patterning defects
178 efects in the heterozygotes included midline diaphragmatic hernias, dilated distal airways, and cardi
179 sophageal junction (GEJ) and the apex of the diaphragmatic hiatus after maximal thoracic esophagus mo
181 ion of the gastroesophageal junction and the diaphragmatic hiatus were 0.88 and 0.85, respectively.
182 lso indicate that differential regulation of diaphragmatic IGF-1-PI3K-Akt signalling exists during th
184 he combination of 18 to 69 hours of complete diaphragmatic inactivity and mechanical ventilation resu
185 n for 18 to 69 hours; among control subjects diaphragmatic inactivity and mechanical ventilation were
187 tly revealed that 18 to 69 hours of complete diaphragmatic inactivity associated with mechanical vent
188 versupply relative to demand, resulting from diaphragmatic inactivity during MV, could play an import
192 o retrospectively determine the frequency of diaphragmatic injury when percutaneous hepatic radiofreq
193 synchronies, ventilator-induced lung injury, diaphragmatic injury, and cardiovascular complications.
194 rs adjacent to the diaphragm, five (17%) had diaphragmatic injury, which was clinically apparent with
197 athing-which effectively pull in air-are the diaphragmatic, intercostal, spine, and neck muscles.
199 controlled ventilation, we assessed in vitro diaphragmatic isometric and isotonic contractile functio
200 ions with assisted mechanical ventilation on diaphragmatic isometric, isotonic contractile properties
201 ingly, independent of MV, apocynin increased diaphragmatic levels of calpastatin, an endogenous calpa
202 on with time-matched controls, did not alter diaphragmatic levels of Type I and IIx myosin heavy chai
204 velopment of new medicines that can maintain diaphragmatic mass and function during prolonged mechani
205 meters (peak Pdi, pressure-time product, and diaphragmatic maximal relaxation rate) were recorded sim
207 mechanical ventilation-induced increases in diaphragmatic mitochondrial reactive oxygen species emis
209 was terminated on any perceived reduction in diaphragmatic motion or a 30% decrease in the compound m
210 ore marked in the 33 PVs with a reduction in diaphragmatic motion than in those without (40.9+/-15.3%
211 c TDI was performed to assess the pattern of diaphragmatic motion velocity, measure its normal values
215 usions but also look at lung recruitment and diaphragmatic movement, hence can aid in deciding extuba
218 e to the diaphragm to assess the velocity of diaphragmatic muscle motion during contraction and relax
220 Prolonged mechanical ventilation results in diaphragmatic oxidative injury, elevated proteolysis, fi
221 trophy and weakness are associated with both diaphragmatic oxidative stress and protease activation.
222 n mice, induction of hyperlipidemia worsened diaphragmatic oxidative stress during MV, whereas transg
223 late that this ventilator-induced decline in diaphragmatic oxygenation could promote a hypoxia-induce
224 gement including noninvasive ventilation and diaphragmatic pacing, secretions, nutrition, dysphagia a
225 A group of 13 patients with early onset diaphragmatic palsy in association with a progressive ne
228 rred in 3 patients (5.8%): one had transient diaphragmatic paralysis, one vascular access complicatio
231 y, pelvic, parietal anterior, left and right diaphragmatic peritonectomy), 14 visceral resections, 5
233 gmatic and esophageal pressure, twitch trans-diaphragmatic pressure (Tw Pdi), age, and maximal static
235 ed diaphragmatic atrophy is due to increased diaphragmatic protein breakdown and decreased protein sy
236 chain protein synthesis; this depression in diaphragmatic protein synthesis persisted throughout 18
237 ically ventilated for 6, 12, or 18 hours and diaphragmatic protein synthesis was measured in vivo.
238 or regulating mechanical ventilation-induced diaphragmatic proteolysis and contractile dysfunction.
244 intraoperative monitoring demonstrates that diaphragmatic re-approximation and sub-diaphragmatic rel
250 that diaphragmatic re-approximation and sub-diaphragmatic relocation has a greater effect on EGJ com
252 The knowledge of the CT findings suggesting diaphragmatic rupture improves the detection of injuries
254 ntribute to an increased risk of spontaneous diaphragmatic rupture in the absence of a significant pr
260 nd 18PSV promoted a significant decrement in diaphragmatic specific force production, but to a lesser
261 8%), loss of left ventricular capture (10%), diaphragmatic stimulation (2%), loss of right ventricula
266 elaxation.Methods: In 20 healthy volunteers, diaphragmatic TDI was performed to assess the pattern of
270 aphragmatic thickness (D (max)); and average diaphragmatic thickness (D (avg)) on sagittal reconstruc
271 aximal fissural thickness (F (max)); maximal diaphragmatic thickness (D (max)); and average diaphragm
272 ith TDI-maximal relaxation rate.Conclusions: Diaphragmatic tissue Doppler allows real-time assessment
276 are abolished following either bilateral sub-diaphragmatic total truncal vagotomy or brainstem-hypoth
278 ntly increased above their basal levels, and diaphragmatic weakness and further increases in caspase-
279 aling role in mechanical ventilation-induced diaphragmatic weakness and that oxidative stress is an u
280 aling role in mechanical ventilation-induced diaphragmatic weakness and that oxidative stress is requ
281 prolonged mechanical ventilation results in diaphragmatic weakness attributable to fiber atrophy and
282 al muscle fibers is a key pathway leading to diaphragmatic weakness during acute endotoxemia, most li
286 l ventilation is associated with significant diaphragmatic weakness resulting from both myofiber atro
290 sponsible for mechanical ventilation-induced diaphragmatic weakness will provide the knowledge requir
291 unidentified type of infantile myopathy with diaphragmatic weakness, areflexia, respiratory distress
299 und that matching men and women for absolute diaphragmatic work resulted in an equal degree of diaphr