ライフサイエンスコーパス: diathesis

1 ect milder and more severe forms of the same diathesis.

2 roborated histologic evidence of hemorrhagic diathesis.

3 albuminuria and ameliorate the prothrombotic diathesis.

4 sely proportional to the level of underlying diathesis.

5 nasal polyposis, endometriosis, and allergic diathesis.

6 associated with other diseases of the atopic diathesis.

7 ding underwent an investigation for bleeding diathesis.

8 alone may not explain the observed bleeding diathesis.

9 ilies suggests a common, or shared, familial diathesis.

10 hiatric illness (the stressor) but also by a diathesis.

11 sses thought to be important in the allergic diathesis.

12 neonatal hemorrhage and a lifelong bleeding diathesis.

13 essive neurologic dysfunction and a bleeding diathesis.

14 onset forms of this condition share the same diathesis.

15 s associated with ultimate cure of the ulcer diathesis.

16 normal in association with a severe bleeding diathesis.

17 e grossly normal adult mice with no bleeding diathesis.

18 e most serious manifestation of an epileptic diathesis.

19 ever, rash, vomiting, diarrhea, and bleeding diathesis.

20 lls in the esophagus are involved in the EoE diathesis.

21 ted TSP2 KO mice did not rescue the bleeding diathesis.

22 l skin barrier defect, and a profound atopic diathesis.

23 ail-bleeding measurement revealed a bleeding diathesis.

24 rs are manifestations of a common underlying diathesis.

25 ssue damage, and remodeling in the asthmatic diathesis.

26 t limited clinical evidence of an infectious diathesis.

27 evels of FVIII that contribute to a bleeding diathesis.

28 severe manifestations of a common underlying diathesis.

29 th muscle (ASM), contribute to the asthmatic diathesis.

30 coagulant effect that produces a hemorrhagic diathesis.

31 PF4/polyanion antibodies and a prothrombotic diathesis.

32 acute promyelocytic leukemia (APL) bleeding diathesis.

33 tation in von Willebrand disease, a bleeding diathesis.

34 ng response in bone and skin, and a bleeding diathesis.

35 such as purpura, which indicates a bleeding diathesis.

36 3 that, when disrupted, can cause a bleeding diathesis.

37 rt that PEA-BP-I and adult BP-I are the same diathesis, 7 to 8x greater familiality in child vs adult

38 t increased several features of the allergic diathesis (AHR, eosinophilia, and IgE), which was concom

39 or VIPAR, and is associated with a bleeding diathesis and a marked reduction in platelet alpha-granu

40 irculating LPA levels and induced a bleeding diathesis and attenuation of thrombosis in mice.

41 previously known as idiopathic haemorrhagic diathesis and commonly known as bleeding calf syndrome)

42 ction of depression with the alcohol genetic diathesis and disturbed parent model.

43 IFN-alpha/beta-dependent lethal hemorrhagic diathesis and for clearing LCMV infection through CTLs.

44 outcomes are exacerbated by a prothrombotic diathesis and hypokalaemia.

45 essive condition characterized by a bleeding diathesis and hypopigmentation of the skin, hair, and ey

46 can noninvasively characterize the asthmatic diathesis and its severity.

47 marker for early activation of an autoimmune diathesis and likely plays a critical role in triggering

48 tations in RASGRP2 that account for bleeding diathesis and platelet dysfunction in 2 unrelated famili

49 ypass surgery complicated by severe bleeding diathesis, and 3 patients had major bleeding events.

50 mpaired visual acuity, nystagmus, a bleeding diathesis, and absent platelet dense bodies, confirming

51 rvive to adulthood with only a mild bleeding diathesis, and fibrinogen-deficient mice show perinatal

52 medications, chronic lung disease, bleeding diathesis, and immunodeficiency.

53 ere skin disease, hair shaft defects, atopic diathesis, and increased susceptibility for skin infecti

54 nts, including atrial fibrillation, bleeding diathesis, and neutropenia can differ based on which BTK

55 terized by oculocutaneous albinism, bleeding diathesis, and other variable symptoms.

56 yte abnormalities, cardiac failure, bleeding diathesis, and phlebitis.

57 tations that could include rash, hemorrhagic diathesis, and shock.

58 nts have oculocutaneous albinism, a bleeding diathesis, and sometimes develop granulomatous colitis o

59 Thus, the bleeding diathesis appears to reflect the absence of platelet fac

60 allergic responsiveness) resulting in asthma diathesis are discussed.

61 ition difficulties to create a depressogenic diathesis as at-risk females reach puberty.

62 onality disorder, which has the same genetic diathesis as schizophrenia, manifests abnormalities in w

63 The in vivo bleeding diathesis as well as the defects in platelet responses t

64 The bleeding diathesis associated with congenital deficiency of facto

65 The bleeding diathesis associated with hereditary factor XI (fXI) def

66 activity (400%), correction of the bleeding diathesis at clinically relevant, low vector doses (5 x

67 nd from a male patient (S14) with a bleeding diathesis attributed to a single amino acid substitution

68 gesting persistence of an underlying disease diathesis between episodes.

69 iciency is associated with a severe bleeding diathesis but no developmental abnormalities, lending we

70 XI deficiency is associated with a bleeding diathesis, but factor XII deficiency is not, indicating

71 None of these lines had an overt bleeding diathesis, but in a FeCl(3) carotid artery thrombosis mo

72 and major depression share a common genetic diathesis, but the anxiety disorders themselves are gene

73 (vWD) is the most common hereditary bleeding diathesis, but the estimated prevalence of acquired vWD

74 L-21 plays an important role in the allergic diathesis by enhancing Th2 cytokine production through m

75 Hemophilia is an X-linked bleeding diathesis caused by a deficiency of either factor VIII o

76 Hemophilia B is a severe X-linked bleeding diathesis caused by the absence of functional blood coag

77 type that promotes the pronounced thrombotic diathesis characteristic of the hypereosinophilic syndro

78 use gray platelet syndrome (GPS), a bleeding diathesis characterized by a lack of alpha granules in p

79 could be explained by the genetic alcoholic diathesis combined with an environmental factor that was

80 We speculate that this underlying diathesis could alter the temporal and spatial cascade o

81 thrombospondin-2 (TSP2), display a bleeding diathesis, despite normal blood coagulation and the lack

82 fied in patients diagnosed with the bleeding diathesis disorder, von Willebrand disease (vWD), on the

83 failure (FHF) in humans produces a bleeding diathesis due in large part to a reduction in the biosyn

84 ed by oculocutaneous albinism and a bleeding diathesis due to absent platelet delta granules.

85 ng of oculocutaneous albinism and a bleeding diathesis due to the absence of platelet dense granules,

86 Atopic diathesis encompassing atopic dermatitis (AD), allergic

87 enied having prior trauma, surgery, bleeding diathesis, fever, chills, or vision changes.

88 f childhood abuse that may contribute to the diathesis for adulthood psychopathological conditions.

89 ic trait variables associated with a genetic diathesis for anorexia nervosa.

90 Chronic stress is a strong diathesis for depression in humans and is used to genera

91 critical time for the emergence of a genetic diathesis for disordered eating.

92 the amygdala and hippocampus may be a shared diathesis for later negative outcomes related to ELS.

93 High hypnotizability may be a diathesis for pathological dissociative states, particul

94 tions are related to the underlying familial diathesis for psychotic disorders.

95 renia patients, who likely share the genetic diathesis for schizophrenia but not the potential confou

96 that are differentially associated with the diathesis for schizophrenia.

97 y-adrenal axis stress-response system in the diathesis for suicidal behaviour.

98 he hypothalamic-pituitary-adrenal axis, as a diathesis for suicide.

99 develop a coherent model for the biological diathesis for suicide.

100 due, at least in part, to a greater familial diathesis for the disorder.

101 before any childhood adversity and may be a diathesis for the interaction between CRHR1 genotypes an

102 The bleeding diathesis has been attributed to delta storage pool defi

103 rocytosis, increased thrombotic and bleeding diathesis, high arrhythmogenic risk, progressive heart f

104 with pathophysiologic importance for the SLE diathesis in African Americans.

105 ene product and amelioration of the bleeding diathesis in animals with hemophilia B.

106 2 antibodies contribute to the prothrombotic diathesis in antiphospholipid syndrome.

107 ited platelet defect accounts for a bleeding diathesis in approximately 1:20,000 individuals.

108 els (8I U/mL) and correction of the bleeding diathesis in FIX knock-out mice.

109 let FVIII demonstrably improved the bleeding diathesis in FVIIInull mice independent of the platelets

110 and demonstrate amelioration of the bleeding diathesis in haemophilia B mice.

111 C)-2 is associated with only a mild bleeding diathesis in humans and mice.

112 ed the existence of a generalized autoimmune diathesis in patients with multiple sclerosis.

113 as contributors to the increased thrombotic diathesis in the hearts of COVID-19 patients.

114 sumptive coagulopathy underlies the bleeding diathesis in these older embryos.

115 lar matrix (ECM) abnormality to the bleeding diathesis in thrombospondin-2 (TSP2) knockout (KO) mice.

116 l prefrontal cortex (vmPFC)) and this stress diathesis, in maltreated youth were not previously inves

117 However, other indicators of bipolar diathesis including recent maniclike symptoms and family

118 g from additive or multiplicative effects of diathesis, including culture, and stressful experiences.

119 studies indicate a biological basis for this diathesis, indicating the importance of neurobiological

120 This diathesis is expressed as the tendency to develop more p

121 The characteristic bleeding diathesis is the most notorious manifestation of the dis

122 This diathesis may be reflected in tendencies to experience m

123 d lifelong severe thrombocytopenia, bleeding diathesis, mental retardation, mitral valve prolapse, an

124 Biomarkers related to the diathesis might help to inform risk-assessment procedure

125 ) associated with thrombocytopenia, bleeding diathesis, miosis, and tubular myopathy in patients with

126 A testable, evidence-based stress-diathesis model can inform nuanced understanding of how

127 tigated the predictive potential of a stress-diathesis model for suicidal behavior based on correlate

128 The authors propose a stress-diathesis model in which the risk for suicidal acts is d

129 The stress-diathesis model may not be an appropriate paradigm for p

130 The stress-diathesis model posits that suicide is the result of an

131 ted for phobias the prediction of the stress-diathesis model that the magnitude of stress at onset is

132 None of the 3 tests of the stress-diathesis model was confirmatory: (1) the risk of phobia

133 Third, we advocate a stress-diathesis model, in which biological susceptibility inte

134 This review includes a hypothesized stress-diathesis model, which has implications for detection of

135 hose oculocutaneous albinism (OCA), bleeding diathesis, neutropenia, and history of recurrent infecti

136 letion phenotypically overlaps with bleeding diathesis observed in patients with NS.

137 various expressions of an underlying common diathesis of abnormal regulation of basic threat-respons

138 s, infection may have a role in the bleeding diathesis of cirrhosis.

139 mplicated recently in some of the infectious diathesis of cystic fibrosis.

140 ic expression of hFVIII rescued the bleeding diathesis of hemophilic mice lacking endogenous FVIII.

141 g human factor IX could correct the bleeding diathesis of mice with hemophilia B.

142 reactivity is associated with an autoimmune diathesis of the mother.

143 nd their absence contributes to the bleeding diathesis of Wiskott-Aldrich syndrome.

144 trate how multiple risk factors and a family diathesis often go undetected, resulting in tragic conse

145 ion in females was predicted by an alcoholic diathesis only when combined with the disturbed adoptive

146 t (environmental) stressors and a trait-like diathesis or susceptibility to suicidal behaviour, indep

147 on the depression risk are dependent on the diathesis or vulnerability, implying multiplicative inte

148 response, microbiome alterations, a genetic diathesis, or a combination of these and other factors.

149 bilateral fixed and dilated pupils, bleeding diathesis, or unsurvivable injury.

150 Our results provide support for the stress-diathesis perspective and validate the scientific contri

151 m disease proposes that an alcoholic genetic diathesis predisposes to depression in females but alcoh

152 tigated a small Dutch family with a bleeding diathesis, prolonged prothrombin, and activated partial

153 e promyelocytic leukemia leads to a bleeding diathesis reflective of excessive cell surface annexin 2

154 17F mutation, but its role in the thrombotic diathesis remains obscure.

155 nts, especially those with a severe bleeding diathesis, significantly easier and safer.

156 had altered platelet biology and a bleeding diathesis similar to that seen in patients with Quebec p

157 he interaction with MAOA-LPR better fits the diathesis stress model, with the 3.5R/4R allele conferri

158 n the level of food reinforcement, while the diathesis stress or dual-gain model only influences one

159 lysis of differential susceptibility (versus diathesis stress) are reviewed.

160 The findings support a diathesis-stress hypothesis in which genetically seizure

161 associations may be important players in the diathesis-stress model for suicidal behaviors.

162 or depression, supporting the multiplicative diathesis-stress model for this disease.

163 This supports a diathesis-stress model in which different complex adapti

164 on health have relied heavily on the classic diathesis-stress model that treats genetic variations an

165 The authors propose a diathesis-stress model to describe how pathological diss

166 Histories of the diathesis-stress model trace its origins to the 1950s.

167 xperiences, highlighting the importance of a diathesis-stress or bioecological framework for understa

168 depression, does not synergize with SES in a diathesis-stress relation, nor does it mediate the relat

169 The diathesis-stress theory for depression states that the e

170 The dominant ('general') version of the diathesis-stress theory of depression views stressors an

171 ntal, and epigenetic roots consistent with a diathesis-stress theory of depression.

172 This hypothesis is often tested with a "diathesis-stress" model, in which genes confer excess vu

173 t from anticoagulation coupled with bleeding diathesis such as acquired von Willebrand syndrome.

174 veloped normally with no signs of a bleeding diathesis, suggesting that low TF expression can maintai

175 associated with a mild to moderate bleeding diathesis that is most commonly found in persons of Jewi

176 cal data pertaining to a specific MS genetic diathesis to depression and the absence of a clear sex d

177 y, the biological substrates underlying this diathesis to medical and psychiatric morbidity have been

178 rize the work that has defined the inherited diathesis toward atrial fibrillation, outline the geneti

179 nding of the molecular basis of the bleeding diathesis type 2N VWD.

180 e genetics of brain function and the genetic diathesis underlying complex psychiatric disorders.

181 A bleeding diathesis was clinically evident from days 5 to 12 after

182 Phenotypic correction of the bleeding diathesis was demonstrated by survival of all treated mi

183 In contrast, bleeding diathesis was observed in mice with a 90% but not with a

184 The predictive potential of the diathesis was tested by determining whether clinical cor

185 o identify the genetic cause of the bleeding diathesis, we performed whole exome sequencing analysis

186 Although CD36(-) mice do not have a bleeding diathesis, we show here that they do have significantly

187 e design, there remains an apparent bleeding diathesis, which leads to increased transfusion requirem

188 are manifestations of an affective disorder diathesis with a puerperal trigger.

189 gests that CUD may share a common underlying diathesis with BP-II.