ライフサイエンスコーパス: dieldrin

1 BAA antagonist (bicuculline or the pesticide dieldrin).

2 e that confers resistance to the insecticide dieldrin.

3 y; however, a suggestive finding emerged for dieldrin.

4 etic mapping of resistance to the cyclodiene dieldrin.

5 e.g., DDT in the western part of Germany and dieldrin.

6 ncrease in basal [Ca(2+)](i) is inhibited by dieldrin.

7 of these two agents than of chlorpyrifos and dieldrin.

8 rgic neuronal degeneration after exposure of dieldrin.

9 ate both receptors, such as clotrimazole and dieldrin.

10 (GABA) receptor subunit gene, Resistance to dieldrin.

11 oxic cyclodiene compounds such as aldrin and dieldrin.

12 ing gestation and lactation to low levels of dieldrin (0.3, 1, or 3 mg/kg every 3 days) alters dopami

13 or pendimethalin (1.50; 95% CI: 0.98, 2.31), dieldrin (1.93; 95% CI: 0.70, 5.30), and chlorimuron eth

14 veloped resistance to insecticides including dieldrin, 1,1-bis(p-chlorophenyl)-2,2,2-trichloroethane

15 ns, which were countered by bicuculline (and dieldrin, 5-HT neurons only).

16 Dieldrin, a highly persistent organochlorinated pesticid

17 In this paper we describe the effect of dieldrin and a binary mixture of dieldrin and lindane on

18 The combined findings indicate that dieldrin and binary mixtures of organochlorines affect [

19 e effect of dieldrin and a binary mixture of dieldrin and lindane on a critical parameter of neuronal

20 Co-exposure of PC12 cells to a mixture of dieldrin and lindane revealed an additive inhibition of

21 Surprisingly, the effects of diazinon, dieldrin and Ni(2+) showed basic similarities despite th

22 ike, whereas there was strong concordance of dieldrin and Ni(2+) with each other and with each indivi

23 orpyrifos, diazinon) with an organochlorine (dieldrin) and a metal (Ni(2+)) for similarities and diff

24 (chlorpyrifos, diazinon), an organochlorine (dieldrin) and a metal (Ni(2+)) for their effects on neur

25 (chlorpyrifos, diazinon), an organochlorine (dieldrin) and a metal (Ni(2+)); we utilized microarrays

26 polychlorinated biphenyls, DDTs, chlordanes, dieldrin, and alpha- and gamma-hexachlorocyclohexane (HC

27 Gaseous concentrations of hexachlorobenzene, dieldrin, and chlordanes were significantly greater (Man

28 400 and -200 (pg.m(-2).d(-1)) for gamma-HCH, dieldrin, and chlorpyrifos, respectively.

29 ce for an association between pendimethalin, dieldrin, and parathion use and lung cancer risk.

30 id (2,4,5-T); the organochlorine insecticide dieldrin; and the organophosphate insecticides diazinon,

31 The halving times for DDTs, chlordanes, and dieldrin are 8.7 +/- 0.4 years for both the atmosphere a

32 her OCPs, such as chlordanes, heptachlor and dieldrin, are steady and/or declining slowly at the majo

33 ctures such as diazinon, heptachlor, endrin, dieldrin, butachlor and chlordane.

34 demonstrate that nanomolar concentrations of dieldrin can stimulate microglia to produce ROS that may

35 ropionic acid (2,4,5-TP) and possibly use of dieldrin, captan, and 2,4,5-trichlorophenoxyacetic acid

36 Elevated levels of dieldrin, chlordane- and DDT-related pesticides, polycyc

37 Dissolved SigmaHCH and dieldrin concentrations decreased linearly with increasi

38 ors (TN, CN), heptachlor exo-epoxide (HEPX), dieldrin (DIEL), chlorobornanes (SigmaCHBs and toxaphene

39 nazine, picloram, aldicarb, azinphos-methyl, dieldrin, diquat dibromide, endosulfan, and esfenvalerat

40 t Austfonna, but not at Holtedahlfonna where dieldrin dominated.

41 of two weak environmental estrogens, such as dieldrin, endosulfan, or toxaphene, were 1000 times as p

42 0 POPs (aldrin, chlordane, chlordecone, DDT, dieldrin, endrin, endosulfan, HBCDD, HCB, HCHs, heptachl

43 a greater reduction of striatal dopamine in dieldrin-exposed offspring, which was associated with a

44 Additionally, dieldrin exposure during development potentiated the inc

45 porter 2 (VMAT2) were increased by perinatal dieldrin exposure in a dose-related manner.

46 istone acetylation occurred within 10 min of dieldrin exposure indicating that acetylation is an earl

47 of microglial cells with 0.1 nM to 1 microM dieldrin for 24 h resulted in a concentration-dependent

48 receptors, and overlap between diazinon and dieldrin for the receptors led to a stronger resemblance

49 The Resistance to Dieldrin gene, Rdl, encodes a GABA-gated chloride channe

50 d by reduced dosage of the Rdl (Resistant to dieldrin), gene encoding a subunit of inhibitory GABA re

51 However, dieldrin had more notable effects on neuropeptide recept

52 chlorine (OC) insecticides lindane (HCH) and dieldrin (HEOD) to the development of neurodegenerative

53 dichlorodiphenyltrichloroethane (p,p -DDT), dieldrin, heptachlor epoxide, HCB, trans-nonachlor, oxyc

54 Furthermore, 30-day exposure of dieldrin in mouse models induced histone hyperacetylatio

55 ease mitochondrial basal oxygen consumption; dieldrin increased basal oxygen consumption; trifluralin

56 n addition to immortalized microglial cells, dieldrin induced a concentration-dependent ROS generatio

57 n mesencephalic dopaminergic neuronal cells, dieldrin induced a time-dependent increase in the acetyl

58 tment on histone acetylation and its role in dieldrin-induced apoptotic cell death in dopaminergic ne

59 itor anacardic acid significantly attenuated dieldrin-induced histone acetylation, Protein kinase C d

60 Furthermore, the dieldrin-induced microglial ROS generation was significa

61 The dieldrin-induced microglial ROS generation was time-depe

62 mation on the potential role of microglia in dieldrin-induced neurodegeneration in relevance to the d

63 The hyperacetylation was attributed to dieldrin-induced proteasomal dysfunction, resulting in a

64 te that exposure to the neurotoxic pesticide dieldrin induces acetylation of core histones because of

65 n particular, the organochlorine insecticide dieldrin is believed to be associated with PD.

66 data suggest that developmental exposure to dieldrin leads to persistent alterations of the developi

67 ion of the organochlorine pesticides aldrin, dieldrin, lindane, and alpha-endosulfan by using surface

68 Compared with those in the lowest quintile (dieldrin, < 0.57 mug/L), odds of obesity were 3.6 (95% C

69 des (desulfinylfipronil, AMPA, chlorpyrifos, dieldrin, metolachlor, atrazine, CIAT, glyphosate) and t

70 n Vallee du Kou (VK) to pyrethroids, DDT and dieldrin, moderate level for carbamates and full suscept

71 cating that acetylation is an early event in dieldrin neurotoxicity.

72 study, we set out to determine the effect of dieldrin on the production of ROS and the underlying mec

73 With the exception of dieldrin, our data shows PCBs and other organochlorine p

74 effects on both 5-HT and TH neurons, whereas dieldrin potently inhibited 5-HT neurons only.

75 ide F receptor (sNPFR), and the resistant to dieldrin (RDL) category of GABA receptors.

76 ns in duplicated copies of the Resistance to dieldrin (Rdl) gene that encodes the GABA receptor, and

77 levels of the GABA(A) receptor resistance to dieldrin (RDL) in the wake-promoting large ventral later

78 us (Phh) GABA receptor subunit resistance to dieldrin (RDL) is the target of lotilaner, a synthetic m

79 GABA-gated chloride channels (resistance to dieldrin (RDL) receptors).

80 acid decarboxylase 1 (Gad1) and Resistant to dieldrin (Rdl), genes vital for GABAergic neurotransmiss

81 n of the GABA(A) receptor gene, Resistant to dieldrin (Rdl), in PDF neurons reduces sleep, consistent

82 The GABAA receptor, resistance to dieldrin (Rdl), is highly expressed in the Drosophila mu

83 teracts with the GABAA receptor Resistant to Dieldrin (RDL), upregulating its levels and promoting it

84 le point mutations in the gene Resistance to dieldrin (Rdl), which codes for a subunit of a gamma-ami

85 ect GABA-gated chloride channel resistant to dieldrin (Rdl).

86 t from Drosophila melanogaster [Resistant to Dieldrin (RDL)] has been cloned, functionally expressed,

87 channel (vgsc); GABA receptor (resistance to dieldrin, rdl); acetylcholinesterase (ace-1); and glutat

88 rdance between Ni(2+) and either diazinon or dieldrin, reflecting similarities toward the receptors.

89 o includes a biochemical selectable markers, Dieldrin resistance (Dl), on the second chromosome and f

90 ilide via the A296S mutation associated with dieldrin resistance (rdl).

91 s with this duplication exhibit intermediate dieldrin resistance compared with single copy Ser(301) h

92 strong correlation with pyrethroids/DDT and dieldrin resistance.

93 e complete mortality of An. arabiensis SENN (dieldrin-resistant), compared to its susceptible counter

94 Surprisingly, dieldrin shared many of the same neuropeptide targets as

95 ic samples; however, some compounds (such as dieldrin) showed reduced concentrations from 7.5-3.4 to

96 ptors is constructed from RDL (resistance to dieldrin) subunits from Drosophila melanogaster.

97 whereas losses exceeding 80% were found for dieldrin, sulfotep or phorate.

98 d among users of the chlorinated insecticide dieldrin, the fumigant mixture carbon-tetrachloride/carb

99 demonstrate that nanomolar concentrations of dieldrin time- and concentration-dependently inhibit dep

100 The most commonly detected pesticides were dieldrin, trans-chlordane, endosulfan I, and chlorpyrifo

101 In this study, we examined the effects of dieldrin treatment on histone acetylation and its role i

102 observed in cells 12-24 h, but not 6 h after dieldrin treatment.

103 rved effect concentrations for chlorpyrifos, dieldrin, trifluralin, and p,p'-dichlorodiphenyldichloro

104 Aldrin and dieldrin were less potent than endrin in interfering wit

105 nochlorine pesticides, the most abundant was dieldrin, with the highest average concentration of 99 +