ライフサイエンスコーパス: differential expression

1 bias in the estimation of both absolute and differential expression.

2 ntrol and infected cells with no evidence of differential expression.

3 ariability and to increase power for testing differential expression.

4 d allowed the detection of relatively subtle differential expression.

5 sociated with these early and later waves of differential expression.

6 on a cytokine/chemokine panel for potential differential expression.

7 tive patterns and often show tissue-specific differential expression.

8 e gene selection, dimensional reduction, and differential expression.

9 ations into account in the analysis of miRNA differential expression.

10 e of both within-lineage and between-lineage differential expression.

11 ence, or fail to pinpoint the exact types of differential expression.

12 imed to identify miRNAs that show consistent differential expression across all published expression

13 hese mutant-specific genes showed consistent differential expression across ER-mutant lines developed

14 ies to monitor the developmental dynamics of differential expression, additivity for gene expression,

15 The dynamic nature of differential expression, additivity, and regulatory vari

16 sometimes be large and can affect downstream differential expression analyses as well.

17 Subsequent differential expression analyses based on datasets integ

18 o persuade 1) users to slightly modify their differential expression analyses by incorporating statis

19 multiple experiments and the results of two differential expression analyses in which we successfull

20 Differential expression analyses significantly correlate

21 was obtained using Illumina HiSeq 2500, and differential expression analyses were performed using DE

22 just for confounding effects of cell type in differential expression analysis (DEA).

23 sion level needs to be considered, requiring differential expression analysis across samples.

24 s of coding and noncoding genes, (b) perform differential expression analysis across thirteen cancer

25 cal analyses include co-expression analysis, differential expression analysis and differential correl

26 bayNorm improves accuracy and sensitivity of differential expression analysis and reduces batch effec

27 at the cone pedicle, we performed an RNA-seq differential expression analysis between cone-specific B

28 We used differential expression analysis combined with weighted

29 Most popular methods for RNA-seq differential expression analysis fit a parametric model

30 ch allows for simultaneous normalization and differential expression analysis from log-transformed RN

31 Differential expression analysis generated gene lists th

32 Differential expression analysis identified 699 signific

33 Differential expression analysis identified cell type-sp

34 Differential expression analysis identifies global chang

35 gene expression heritability estimation and differential expression analysis in a large RNA sequenci

36 hroughput sequencing experiments followed by differential expression analysis is a widely used approa

37 A fundamental step in differential expression analysis is to model the associa

38 Differential expression analysis of mRNA from chondrocyt

39 Differential expression analysis of mRNA-seq data reveal

40 is of ATAC-seq shares many similarities with differential expression analysis of RNA-seq data.

41 outperform univariate methods developed for differential expression analysis of RNA-seq data.

42 Differential expression analysis of the alternatively sp

43 (miRNA) were sequenced and quantified, and a differential expression analysis of the two RNA populati

44 In this study, we performed joint differential expression analysis on the RNA-sequencing d

45 A differential expression analysis restricted to the 40 to

46 Genome-wide RNA-seq and differential expression analysis reveal differences in a

47 Differential expression analysis revealed, 160 transcrip

48 Differential expression analysis showed that most of the

49 datasets and can alter the conclusions of a differential expression analysis study.

50 A differential expression analysis technology developed fo

51 Here, we present a differential expression analysis toolkit, DEvis, that pr

52 This tool increases the capabilities of differential expression analysis while reducing workload

53 able to identify the features in downstream differential expression analysis with high accuracy when

54 (DiffExPy), that uniquely combines discrete, differential expression analysis with in silico differen

55 me datasets in co-expression analysis and in differential expression analysis with obesity-related tr

56 with diverse applications to gene discovery, differential expression analysis, eQTL prioritization, a

57 Although there are many methods for RNA-seq differential expression analysis, existing methods do no

58 Using differential expression analysis, gene set enrichment an

59 Using abundance estimation (RSEM) and differential expression analysis, genes that were signif

60 logical purposes, including quality control, differential expression analysis, pathway enrichment ana

61 r the studied or related species followed by differential expression analysis, quantitative PCR valid

62 al data, as well as the effect on subsequent differential expression analysis.

63 th in terms of quantification and downstream differential expression analysis.

64 ent analysis (PCA) indicated high quality of differential expression analysis.

65 ear models with mixed effects are needed for differential expression analysis.

66 alization should be an integral component of differential expression analysis.

67 We compared the three kits in a realistic differential expression analysis.

68 phasis on improving both clustering and gene differential expression analysis.

69 clustering, classification, regression, and differential expression analysis.

70 e sensitivity and specificity of single-cell differential expression analysis: a large proportion of

71 In a differential-expression analysis of a real single-cell R

72 We present Hierarchical Bayesian Analysis of Differential Expression and ALternative Splicing (HBA-DE

73 methylation landscapes, as laid down by the differential expression and binding of other transcripti

74 We also discuss the performance of multiple differential expression and dimension reduction methods

75 In comparisons to differential expression and gene set analysis, we found

76 prioritization to somatic burdening, cancer differential expression and GWAS.

77 of allelic genes, 16.6% and 30.8% exhibited differential expression and methylation between alleles,

78 by cell-type specific innervation patterns, differential expression and postsynaptic targeting of GA

79 propose a set-based procedure for testing of differential expression and show that this set-based app

80 A-DEALS), which simultaneously characterizes differential expression and splicing in cohorts.

81 sed for benchmarking methods for clustering, differential expression and trajectory inference, and fo

82 ladder tissue vasculature was compared using differential expression and unsupervised hierarchical cl

83 normalization, temporal dynamics (temporally differential expression), and isoform diversity (isoform

84 lso generated RNA-sequencing data, performed differential expression, and constructed weighted gene c

85 mall molecule, reporting the significance of differential expression as determined by the limma metho

86 osed cells identified critical genes showing differential expression associated with both individual

87 were identified where transcripts exhibiting differential expression (associated with single generati

88 Although we found very little overlap of differential expression at the level of individual genes

89 o BCMA-like molecules are suggested by their differential expression before and after activation of t

90 he QTL associated with C16:0 content, showed differential expression between developmental stages, po

91 all life stages, there were 5,042 genes with differential expression between life stages (significant

92 SPE can arise from differential expression between parental alleles, termed

93 andidate protein biomarkers with significant differential expression between patients that relapsed v

94 miRNAs were assessed for differential expression between previously assigned lung

95 n the chlorophyll degradation pathway showed differential expression between resistant and susceptibl

96 stepwise filtering for expression in styles, differential expression between species, correlation wit

97 No constitutive differential expression between strains was detected, bu

98 to a single-cell RNA-seq dataset, assessing differential expression between sub-populations of cells

99 ance gene Slit2 in endothelium, establishing differential expression between the endothelial (high Sl

100 om the same miRNAs, termed as a multivariate differential expression by Hotelling's T2 test (MDEHT).

101 We validated differential expression by using qRT-PCR and found that

102 ted with various analytical tools, including differential expression, coexpression, and pathway enric

103 airwise comparisons within a single A-Lister differential expression command.

104 were no genes with statistically significant differential expression compared to controls.

105 is the difficulty of distinguishing between differential expression comprising part of the genomic d

106 ols for the aggregation and visualization of differential expression data have discrete functionality

107 ful, integrated solution for the analysis of differential expression data with a rapid turnaround tim

108 Differential expression (DE) analysis and gene set enric

109 ion, rigorous statistical methods to perform differential expression (DE) analysis of circRNAs remain

110 Here, we conducted a differential expression (DE) analysis of season of birth

111 Differential expression (DE) analysis performed on SF ve

112 lization of read counts an essential step in differential expression (DE) analysis.

113 Differential expression (DE) is commonly used to explore

114 d 45 subtypes of solid tumors and quantified differential expression (DE) of GPCRs by comparing tumor

115 for microarray and RNA-seq in the context of differential expression (DE), this topic in the field of

116 graphics have detected normalization issues, differential expression designation problems, and common

117 ation tools can detect normalization issues, differential expression designation problems, and common

118 ation, cell subpopulation identification and differential expression detection in scRNA-seq data.

119 However, the majority of genes with differential expression do not exhibit consistent differ

120 ation of BAGSE in analyzing real data from a differential expression experiment and a transcriptome-w

121 mple size, only two genes showed significant differential expression (FDR < 10%).

122 in response to heme provide a mechanism for differential expression from co-transcribed genes.

123 Differential expression, functional annotation, and gene

124 Differential Expression Gene Explorer (DrEdGE) is a web-

125 eq, transcription abundance can be measured, differential expression genes between groups and functio

126 ve a role in transcription, with evidence of differential expression in 50 genes across lineage 4 sam

127 and proteomics analysis of the EVs revealed differential expression in a number of mRNA, proteins, a

128 Many (~74%) of the expressed genes exhibit differential expression in at least one tissue.

129 ng several pathways of glycan synthesis show differential expression in brains of individuals with sc

130 dentify novel and uncharacterized TTSPs with differential expression in breast cancer and to determin

131 1.5; adjusted-p <= 0.05) showed significant differential expression in comparison to control.

132 rential expression do not exhibit consistent differential expression in different tissues.

133 , multiple epigenetic modifying enzymes show differential expression in early sepsis, suggesting a ro

134 s breakpoints, with some showing evidence of differential expression in human and macaque cell lines,

135 Refractory subpopulations have differential expression in pathways involved in cell cyc

136 everal miRNAs that showed highly significant differential expression in PD.

137 y demonstrated that affected genes displayed differential expression in prostate tumor samples, were

138 We present a hybrid approach, termed Differential Expression in Python (DiffExPy), that uniqu

139 on their proximity to ANT binding sites and differential expression in response to ANT.

140 ethylation is widespread and associated with differential expression in the DeltahsdM transcriptome,

141 We found 80 genes with sex differential expression in the whole DRG transcriptome a

142 then utilize parametric bootstrap to conduct differential expression inference.

143 ciferase reporter assays indicated that this differential expression is due to an extra C/EBPbeta-bin

144 Differential expression is usually quantified as a conti

145 ever, their assembly process, or the role of differential expression isoforms, remain to be determine

146 The differential expression levels of HMGB proteins and/or m

147 enotypes of the knockout mice likely reflect differential expression levels of POLR3G and POLR3GL acr

148 Genes showing significant differential expression (log2FC >= 1, Padj <= 0.05) were

149 equal in terms of genetic translation, their differential expression may be related to noncanonical t

150 shown that nonparametric models for RNA-seq differential expression may have better control of the f

151 and macrophage subsets and whether potential differential expression might have functional consequenc

152 It can be executed in a differential expression mode or generic name list mode.

153 al profiling of dorsal root ganglia revealed differential expression, notably in regulators of neuron

154 prenatal period was directly associated with differential expression of 14 genes; in contrast, during

155 Metformin treatment was associated with the differential expression of 27 miRNAs (including miR-100-

156 d significantly suppressed ATM signaling and differential expression of a network predicted to be con

157 at variations in DNA methylation mediate the differential expression of a novel lncRNA that acts on M

158 munosuppressed SRS1 endotype (p = 0.014) and differential expression of a small number of biologicall

159 tform in single mouse neurons by quantifying differential expression of activity-regulated genes.

160 -of-origin effects (POE) exist when there is differential expression of alleles inherited from the tw

161 athway is a general switch to trans-regulate differential expression of aminopeptidase N and other mi

162 oarray analysis was then used to profile the differential expression of both miRNAs and mRNAs from DA

163 Differential expression of both p27 and NEDD8 was confir

164 Differential expression of carrageenan-related genes was

165 This can be achieved by differential expression of chaperones-balancing foldases

166 inding preference was likely associated with differential expression of chemokine receptors, particul

167 rs are apparent with leaflet specificity and differential expression of complement factors, ECM prote

168 This review expands on the differential expression of Cx-mediated GJIC between CSCs

169 Our findings highlight the differential expression of eleven microRNAs associated w

170 ght(tdT) cell number increased and presented differential expression of endothelial markers compared

171 tudy, we show that MCV sT protein stimulates differential expression of epithelial-mesenchymal transi

172 mined that a lack of SL synthesis results in differential expression of extracytoplasmic function sig

173 mxa genes, consistent with the Ln-switch, no differential expression of formaldehyde conversion genes

174 Thus, differential expression of GATA3 determines the fates an

175 This could be attributed to sex-dependent differential expression of genes (DEGs) involved in noci

176 precisely characterize temporal dynamics in differential expression of genes and other genomic featu

177 We observed that PF triggered differential expression of genes associated with motilit

178 et unknown mechanism, and not necessarily by differential expression of genes encoding specific synth

179 Differential expression of genes enriched in modules rel

180 d with estimated tissue maturity, indexed by differential expression of genes expressed by progenitor

181 By examining the differential expression of genes expressed in cells harv

182 which suggest that genotype and ACC induces differential expression of genes for the biosynthesis pa

183 lumina RNA-Seq to analyse cDNA libraries for differential expression of genes from leaves of ecologic

184 the regulatory network are conserved, while differential expression of genes involved in cell-to-cel

185 s contractile differences that resulted from differential expression of genes involved in microtubule

186 P scarcity invokes differential expression of genes involved in processing

187 In addition, there was differential expression of genes related to innate immun

188 cum and LPAIV highlighted the involvement of differential expression of genes such as Toll-like recep

189 Differential expression of genes was negatively correlat

190 ype binding specificities of rotaviruses and differential expression of histo-blood group antigens (H

191 We hypothesized that differential expression of host genes related to transla

192 sCJD patients, and healthy controls reveals differential expression of hsa-let-7i-5p, hsa-miR-16-5p,

193 icates that prenatal TLR7 activation induces differential expression of hundreds of genes at 13 weeks

194 Additionally, we found differential expression of hundreds of genes, suggesting

195 However, the focus of many studies is on the differential expression of individual genes or on co-exp

196 n factors (TFs) that drive the preferential, differential expression of individual members within gen

197 chanisms of transcriptome diversity, namely, differential expression of isoforms due to alternative s

198 sion and carbon metabolism, resulting in the differential expression of isolate-specific response pat

199 Expression profiling revealed significant differential expression of key transcripts in MCI and AD

200 scriptome profiles were further explored for differential expression of known and new paralogous gene

201 RNA-sequencing revealed differential expression of known root development-relate

202 In the present study HPV16 E6-induced differential expression of lncRNAs, miRNA, and mRNA were

203 RNA-Seq profiling shows differential expression of many transcription factors in

204 Differential expression of mi-RNAs targeting development

205 Differential expression of miR-145 and circ_Lrp6 in muri

206 This study identified differential expression of miR-21-5p and miR-30b-5p in i

207 Accurate detection of differential expression of miRNAs can bring new insights

208 Differential expression of miRNAs contributes to beta-ce

209 actors, approximately 7% was attributable to differential expression of miRNAs, and a lesser proporti

210 trophysiology and gene expression, including differential expression of molecules supporting co-trans

211 Furthermore, we observed differential expression of multiple central renin-angiot

212 were identified based on ultrastructure and differential expression of one of each of the five diffe

213 s exposed to nearly anoxic conditions showed differential expression of over 400 genes, with evidence

214 e gametes prior to fertilization that causes differential expression of parental alleles, mainly in t

215 We map the cell-specific differential expression of prognostically associated sec

216 We observed differential expression of PSST1 and PSST6, which are th

217 an pathogen C. jejuni using RNA-seq revealed differential expression of putative phospholipid biosynt

218 Hi-C was performed on ROs, and differential expression of regional genes and a retinal

219 g in mice hypothalami, which highlighted the differential expression of Rps26 and Dalrd3.

220 The metabolome analysis revealed differential expression of secondary plant metabolites i

221 The differential expression of selected genes was confirmed

222 It has also highlights the differential expression of sets of beta-oxidation protei

223 from C(3) ancestors and are characterized by differential expression of several hundred genes.

224 an MRM-based targeted proteomic method, the differential expression of small GTPase proteins in a ma

225 in an independent adult AD cohort validated differential expression of STS PC1 proteins in the skin

226 The differential expression of STS PC1 proteins was confirme

227 ueness of each cell type further arises from differential expression of surface glycoproteins.

228 subpopulations can be isolated based on the differential expression of TBX5 and NKX2-5, TBX5+NKX2-5+

229 l as variations of the CsTPS gene family and differential expression of terpenoid and cannabinoid pat

230 d, NetGSA that takes into consideration both differential expression of the biomolecules in the pathw

231 esponse to copper supplementation/depletion, differential expression of the copper importer CTR1, and

232 Differential expression of the long noncoding RNA (lncRN

233 h diabetes and of healthy controls and found differential expression of the methyltransferase Setdb2.

234 Differential expression of the RPS27L (40S ribosomal pro

235 We confirmed the differential expression of the shared gene signatures in

236 In this work, we studied the effect of the differential expression of the two primary hypoxia induc

237 of the lipid genes, as well as mutation and differential expression of the up-stream transcription f

238 The differential expression of these multigenic genes provid

239 uencing, which revealed muscle-type-specific differential expression of these novel transcripts.

240 Differential expression of these PE/PPE proteins was obs

241 These mutations induced differential expression of thousands of genes, the major

242 ne expression profiles and can be tracked by differential expression of three marker genes: Wilms' tu

243 Our findings suggest that differential expression of TJ, mucin, and inflammasome-r

244 rvae against axenic nematodes and results in differential expression of Toll and Imd pathway effector

245 er, the mechanisms underlying AS divergence (differential expression of transcript isoforms resulting

246 n IL-12/23p40 regulation correlated with the differential expression of transcription factors cFos an

247 a key role in shaping stem cell hierarchies, differential expression of transcripts only partially ex

248 Our data support that differential expression of tRNA genes regulate noncanoni

249 There were 549 genes with differential expression of two-fold or greater and P < 0

250 impediments to studies aimed at quantitative differential expression of ultralong transcripts.

251 Differential expression of VCAM-1 and intercellular adhe

252 correlate with existing RNA-seq data showing differential expression of VTL4 and VTL8 during early an

253 tion of vascular permeability coincides with differential expression of zebrafish plvap orthologs in

254 an enhancer at 6p22.1 which associates with differential expression of ZSCAN16 (P = 6.6 x 10-4) and

255 The differential expressions of IGF-1R, FOXO3A, and BIM in t

256 Differential expression, pathway enrichment, correlation

257 r of studies K is large, the 3K - 1 possible differential expression pattern categories generated by

258 iation, is down-regulated in RCC and shows a differential expression pattern for two isoforms of 36 a

259 We uncovered new transcripts that share a differential expression pattern with a neighboring gene

260 example 39 different 2-alkylquinolones with differential expression patterns and a similar number of

261 For both mi- and ra-siRNAs, we detected differential expression patterns following genome merger

262 enome Atlas (TCGA) showed the same consensus differential expression patterns for these two pathways

263 r results indicated that HIV-1 perturbed the differential expression patterns of 19 miRNAs (13 upregu

264 etween distantly related phyla is due to the differential expression patterns of conserved "toolkit"

265 highly in omental adipose tissue, indicating differential expression patterns of HOX clusters in adip

266 Importantly, these rhythms drive differential expression patterns of these and several ot

267 The differential expression patterns were confirmed by quant

268 ally, multiple customizable quality control, differential expression plots as well as enrichments and

269 Bioinformatic analyses of genes with differential expression predicted an increase in cancer,

270 etatranscriptomic analyses revealed the same differential expression profile with the capsid as major

271 g 23 microRNAs (miRNAs) having significantly differential expression profiles in response to alcohol.

272 nd proteome shows extensive remodeling, with differential expression profiles of ~1100 transcripts an

273 f Z-linked genes than autosomal genes showed differential expression, providing evidence for a fast-Z

274 e implicated in non-overlapping functions by differential expression regulation and unique interactio

275 Finally, we observed differential expression related to microglial activation

276 e reasonably robust expression estimates and differential expression results at the isoform level.

277 Their differential expression results in p53 downregulation in

278 achieve more robust expression estimates and differential expression results than single-end reads of

279 ter motif sites that correlate with elevated differential expression scores.

280 eading, so we further demonstrate the use of differential expression strategies to determine true par

281 e sample size and estimate power for RNA-Seq differential expression studies using such designs.

282 e quantitation, which limits its utility for differential expression studies.

283 ng and metabolic inputs that trigger tubulin differential expression, suggesting their novel, to our

284 scHOT meaningfully adds to first-order differential expression testing and provides a framework

285 Using a combination of differential expression testing, upstream regulator anal

286 Across an array of metrics, differential expression tests based upon 2 x 40 consiste

287 trol and disease-does not require choosing a differential expression threshold and can be computed ef

288 a framework for power estimation of RNA-Seq differential expression under complex experimental desig

289 ls or introduce spurious noise in downstream differential expression, unsupervised clustering, and ps

290 al versus blood eosinophil counts as well as differential expression using a blood eosinophil > 200 c

291 Genes were compared for differential expression using DESeq2.

292 Using differential expression, variance partitioning, and co-e

293 We identified loci where polymorphism or differential expression was associated with either a lat

294 Differential expression was found in some telencephalic

295 A list of genes with significantly differential expression was obtained by analyzing the RN

296 Validation of the differential expression was performed via qRT-PCR and im

297 In addition to differential expression, we saw evidence of spatial reor

298 tion based procedure for power estimation of differential expression with the employment of generaliz

299 pose a new procedure for power estimation of differential expression with the use of a bivariate nega

300 in is regulated via typical enhancers, while differential expression within individual feathers corre