ライフサイエンスコーパス: differentiation process

1 oRdelta, which appears to help regulate this differentiation process.

2 s essential for this crossover/non-crossover differentiation process.

3 r checkpoint in the T(CM) to T(EM) phenotype differentiation process.

4 e not been thought to play a role in the mDA differentiation process.

5 res additional signals that will trigger the differentiation process.

6 believe they are important regulators of the differentiation process.

7 multiple epigenomic marks during a cellular differentiation process.

8 luripotent cells, which decreased during the differentiation process.

9 ates genes in naive T cells that control the differentiation process.

10 STAT4 signaling pathway during the early Th1 differentiation process.

11 genes are coordinately regulated during the differentiation process.

12 increase dramatically and rapidly during the differentiation process.

13 dykinin in the middle and late stages of the differentiation process.

14 criptional regulators of the human monocytic differentiation process.

15 hly dynamic and gradually expands during the differentiation process.

16 anscript during the first 4 days of the hESC differentiation process.

17 lities offer a clonal perspective of the HSC differentiation process.

18 ed by decidual laminins, also inhibited this differentiation process.

19 for predetermination of cell fate during the differentiation process.

20 s and predicts new Ikaros targets during the differentiation process.

21 ll interfering RNAs against FA2H inhibit the differentiation process.

22 modifications occurred throughout the entire differentiation process.

23 rved in cells at the beginning or end of the differentiation process.

24 icroRNAs at every stage of the mature B-cell differentiation process.

25 cycle regulation for mESCs to enter into the differentiation process.

26 inhibitor, to these mice blocked the stromal differentiation process.

27 the cerebral cortex might be involved in the differentiation process.

28 and these genes are downregulated during the differentiation process.

29 ghtly regulated with the host cell cycle and differentiation process.

30 ble but also biologically relevant to muscle differentiation process.

31 ges, although MyoD is present throughout the differentiation process.

32 ance of its stringent regulation during this differentiation process.

33 s localized to the primary cilium during the differentiation process.

34 cement of Wnt4 expression and stimulated the differentiation process.

35 ssion in these cells efficiently blocked the differentiation process.

36 icated they are likely to be involved in the differentiation process.

37 ted cells occurred through a Notch-dependent differentiation process.

38 rentiation are expressed during the terminal differentiation process.

39 sequential passage of the cells through the differentiation process.

40 mad4 by RNA interference inhibited the trans-differentiation process.

41 molecules and cytokine receptors direct the differentiation process.

42 ndependent HIF functions are crucial to this differentiation process.

43 protein expression and an attenuation of the differentiation process.

44 signaling mechanisms that participate in the differentiation process.

45 c cells, nuclear Tmod may be involved in the differentiation process.

46 /EBPbeta expression and in turn initiate the differentiation process.

47 derstanding the mechanisms that regulate the differentiation process.

48 e the expression of BMP4 and DCN during this differentiation process.

49 death stimuli is an implicit feature of the differentiation process.

50 that are regulated in the early phase of the differentiation process.

51 tributable to a delay in the timing of their differentiation process.

52 d new insights into the complex postsynaptic differentiation process.

53 s of a polysaccharide as part of a patterned differentiation process.

54 regions that support different phases of the differentiation process.

55 und that this change was a final step in the differentiation process.

56 Skeletal myogenesis is a well-studied differentiation process.

57 is required to act downstream of E2F4 in the differentiation process.

58 ession of TRIB3 in these cells inhibited the differentiation process.

59 n expression on the cell surface during cell differentiation process.

60 erentiating myoblasts and by maintaining the differentiation process.

61 and up-regulation of Smad7 could inhibit the differentiation process.

62 eurons in cell culture throughout the entire differentiation process.

63 establishing ordered structures along their differentiation process.

64 rs are coordinated and integrated during the differentiation process.

65 local microenvironment supports the required differentiation process.

66 ency and regulate gene expression during the differentiation process.

67 er regulatory relationships specific to this differentiation process.

68 , to model regulatory networks specific to a differentiation process.

69 rtant role as a coregulator of the erythroid differentiation process.

70 intermediates to regulate metabolism and key differentiation processes.

71 pects of development, embryogenesis and cell differentiation processes.

72 as drivers of multiple Notch-mediated immune differentiation processes.

73 play key roles in P. patens development and differentiation processes.

74 g with gene transcription to define cellular differentiation processes.

75 s seed formation is coupled with two plastid differentiation processes.

76 for hypothesis generation of underlying ESC differentiation processes.

77 se epidermis impaired both proliferation and differentiation processes.

78 almost exclusively involved in morphogenetic differentiation processes.

79 nderlie cell fate establishment and terminal differentiation processes.

80 fy essential regulators of complex mammalian differentiation processes.

81 ds generated crust and underwent large-scale differentiation processes.

82 ly resulted from complex lunar formation and differentiation processes.

83 rocks reflects 146Sm decayand earlyplanetary differentiation processes.

84 k of requirement for HMGN1 in these cellular differentiation processes.

85 teasome in controlling the proliferation and differentiation processes.

86 ly underlie these endothelial patterning and differentiation processes.

87 transformation usually inhibits normal cell differentiation processes.

88 r 1 (Tcf1) is essential for several of these differentiation processes.

89 ling, muscle contraction, cell migration and differentiation processes.

90 ics in regulating stem cell self-renewal and differentiation processes.

91 oth during development and in adult cellular differentiation processes.

92 genetic pathways governing various cellular differentiation processes.

93 rocess neodymium in the Earth, and not early differentiation processes.

94 r state by inhibiting the plasticity of cell differentiation processes.

95 transcription factors activate a variety of differentiation processes.

96 of core formation and other early planetary differentiation processes.

97 tive and quantitative monitoring of neuronal differentiation processes.

98 essors with crucial roles in development and differentiation processes.

99 fferentiation is closely related to neuronal differentiation processes.

100 of mRNAs that characterize each stage in the differentiation process, (2) that gene expression can be

101 entiation but were essential to complete the differentiation process and drive migration of maturing

102 1 (CRLF1), which is up-regulated during the differentiation process and has been previously implicat

103 ing RNA-mediated EHD2 silencing affected the differentiation process and impaired insulin sensitivity

104 in the dataset, finding driver genes for the differentiation process and obtaining a better understan

105 itries that are controlled by RNA during the differentiation process and that, when deregulated, lead

106 f great interest to understand the bacteroid differentiation process and the roles of energy storage

107 ely expressed at restricted times during the differentiation process and used differential display re

108 R protein expression was enhanced during the differentiation process, and coincubation with its ligan

109 ic cell concentrations, robust regulation of differentiation processes, and robust pulses of cells or

110 surfaceome, is a useful indicator of normal differentiation processes, and the development of pathol

111 Central to this differentiation process are epigenetic modifications wit

112 gnal transduction mechanisms that drive this differentiation process are still not fully understood.

113 These differentiation processes are associated with restricted

114 These carefully regulated differentiation processes are controlled by networks of

115 Thus, some of the fiber differentiation processes are likely mediated by RTK-dep

116 r, the molecular mechanisms underlying these differentiation processes are poorly understood.

117 EKLF also plays a role during the subsequent differentiation process, as it induces p21(WAF1/CIP1) ex

118 WAF) and p27(Kip), were monitored during the differentiation process, as were levels and activities o

119 monolayer systems that fail to reproduce the differentiation processes associated to multilayered sys

120 he molecular signals that drive the synaptic differentiation process at individual synapses in the ce

121 The increased cycling reflects the perturbed differentiation process, because Id1 null HSCs more read

122 corin, an anti-fibrosis agent, prevents this differentiation process by blocking TGF-beta1.

123 Reducing the stochastic effects of the differentiation process by correcting for cell type comp

124 he Hdac inhibitors, (ii) facilitation of the differentiation process by overexpression of the N-termi

125 Akt1 and Akt2 also contribute to the differentiation process by promoting the survival of the

126 To the extent that their fate choice and differentiation processes can be understood and manipula

127 These results suggest that during the early differentiation process CD4 T cells acquire a mixed Th1/

128 Throughout this stepwise differentiation process, changes in anterior neural, ret

129 + cells mechanical properties throughout the differentiation process could enable development of new

130 clude regulators of migration, apoptosis and differentiation, processes crucial for normal developmen

131 e bacteria undergo a host-directed multistep differentiation process culminating in the formation of

132 In the podocyte differentiation process described here, hPSCs are first

133 onal development includes altered maturation/differentiation processes, disturbances in cell-cell com

134 AR3 may antagonize AR activity and halt the differentiation process driven by AR and androgen.

135 Megakaryocytopoiesis is a complex differentiation process driven by the hormone thrombopoi

136 Myogenesis is a tightly regulated differentiation process during which precursor cells exp

137 Cellular differentiation processes during normal embryonic develo

138 en Notch and EGFR signaling that governs the differentiation processes during this period.

139 ssentially every developmental checkpoint or differentiation process encountered by lymphocytes.

140 Through an unusual differentiation process examined in this review, these f

141 Muscle tissue in the early stages of the differentiation process exhibited distinctly higher T1 (

142 Thus, in a late cellular differentiation process, Foxp3 defines Treg cell functio

143 ninvasive in vivo monitoring of the myogenic differentiation process from muscle precursor cells to m

144 This differentiation process from Sox10(+) stem cells to myof

145 ody, bridging a previously persistent gap in differentiation processes from icy cometary bodies to fu

146 time-lapse video microscopy of the stepwise differentiation processes from single progenitors.

147 eural spheroids routinely are created during differentiation processes, further geometric control of

148 Altogether, shared thymic differentiation processes generate "preset" NKT and MAIT

149 eby KLF4 regulates genes associated with the differentiation process has not been studied.

150 (a method used to track each cell though its differentiation process) has demonstrated these potentia

151 imuli and the importance of C/EBPbeta to the differentiation process have led us to hypothesize a rol

152 While key differentiation processes have been characterized at the

153 nd pairs that act in the context of specific differentiation processes have been described.

154 Through an unusual differentiation process, human trophoblast progenitors (

155 Within 2 h of initiation of the differentiation process, HuR complexes containing C/EBPb

156 y human development, we closely examined the differentiation process in adherent colonies of human em

157 t are activated sequentially and control the differentiation process in an overlapping manner.

158 otch signalling is a key event in the normal differentiation process in breast tissue.

159 critical upstream regulatory role in the mDA differentiation process in human pluripotent stem cells.

160 tial molecular regulators in vitro of the NE-differentiation process in lung cancer.

161 n human neurogenesis, we compared the neural differentiation process in mesenchymal stem cells (MSCs)

162 cyte differentiation in vivo we examined the differentiation process in mice null for the expression

163 roles in many cell processes, including the differentiation process in several different lineages.

164 g that SOCS-3 can contribute to the myoblast differentiation process in the absence of IGF-I.

165 took advantage of the local synchrony of the differentiation process in the paraxial mesoderm.

166 Ps) are secreted growth factors that promote differentiation processes in embryogenesis and tissue de

167 are essential for pattern formation and cell differentiation processes in mammals.

168 Notch signaling controls diverse eukaryotic differentiation processes in multiple cell types, thus d

169 cal mechanisms that underlie development and differentiation processes in the Drosophila embryo.

170 There is growing evidence that the differentiation processes in the fetal and adult thymus

171 NT2-mediated regulation of proliferative and differentiation processes in the smooth muscle and may b

172 s involved in embryogenesis, development and differentiation processes in vertebrates.

173 ing signaling molecules that can guide these differentiation processes in vitro, and will be describe

174 As can exert critical control over mammalian differentiation processes in vivo.

175 nderstanding the molecular mechanisms of the differentiation process, in particular neuroendocrine (N

176 highlighted its putative function in neural differentiation processes, including axon guidance as su

177 t revealed a transcriptional reversion of CM differentiation processes, including reactivation of lat

178 1 cells, a physiological C/EBPbeta-dependent differentiation process indicating that the cooperation

179 Furthermore, PPARgamma agonists enhanced the differentiation process initiated by ET-743.

180 olecular effectors involved in executing the differentiation process initiated by TCR-ligand interact

181 ns directly affects flocculation, a cellular differentiation process initiated under conditions of nu

182 CD8 T cells undergo expansion and a dynamic differentiation process into functionally different subp

183 34+ cells, and expelled nuclei, during their differentiation process into red blood cells at days 11,

184 rce of metastatic progenitor cells through a differentiation process involving EMT and mesenchymal-ep

185 We further show that the differentiation process is associated with a striking mo

186 The glial differentiation process is characterized by a marked dow

187 antitative analysis shows that the endocrine differentiation process is consistent with a simple mode

188 In vitro, this differentiation process is facilitated by confluency, fo

189 contrast, in ulcerative colitis, a Th2-like differentiation process is paramount, which results in e

190 Regulation of this differentiation process is poorly understood, but involv

191 This differentiation process is tightly controlled by exogeno

192 The keratinocyte differentiation process is under tight regulation.

193 his microenvironment, their function in this differentiation process is unknown.

194 lecular functions and its roles in any given differentiation process is unknown.

195 The differentiation process is very costly and time-consumin

196 -like peptide (ILP) signaling in sex-related differentiation processes is attracting increasing atten

197 enetic enzymes contribute to development and differentiation processes is largely unclear.

198 An essential feature of the differentiation processes is the assembly of a rigid, ce

199 idermis forms during the course of a complex differentiation process known as cornification, which cu

200 ukemia (AML) is characterized by an impaired differentiation process leading to an accumulation of im

201 obium microsymbionts undergo an irreversible differentiation process leading to the development of el

202 , underwent cell differentiation in vivo The differentiation process led to suppression of p63-expres

203 ach cell line proceeded to completion of the differentiation process like the wild-type cells with th

204 networks using expression data observed in a differentiation process may help identify context-specif

205 Abnormalities of this differentiation process may underlie development of some

206 e degeneration occurs due to an osteoblastic differentiation process mediated by the low-density lipo

207 prevented premature initiation of the fiber differentiation process mediated by the NAC SECONDARY WA

208 ing-dependent systems, such as the epidermal differentiation process, must effectively respond to var

209 on changes in two divergent terminal myeloid differentiation processes, namely MAC and OC differentia

210 and performed a comparative study during the differentiation process, observing significant differenc

211 he tumour, it is critical that this effector differentiation process occur.

212 Simultaneously, a dynamic differentiation process occurs, resulting in the formati

213 on persists concerning their function in the differentiation process of cardiomyocytes.

214 alt and sour, and recapitulate the molecular differentiation process of endogenous taste buds.

215 application toward our understanding of the differentiation process of iPSCs toward hematopoietic pr

216 dermal barrier defects caused by an aberrant differentiation process of keratinocytes are comparably

217 , these relapsed leukemic cells enter into a differentiation process of killer cells.

218 These results thus suggest a delay in the differentiation process of Klhl6-deficient B cells betwe

219 d Wnt signaling likely regulates the overall differentiation process of nail/claw formation.

220 rn of connectivity are likely to control the differentiation process of newly generated neurons and e

221 data demonstrate a key role for Rsk1 in the differentiation process of PC12 cells.

222 fied may improve our understanding of the de-differentiation process of prostate tumors.

223 the expression and function of Ascl1 in the differentiation process of specific neuronal subtypes du

224 ide key insights into poorly understood cell differentiation processes of considerable physiologic re

225 terogeneity truly recapitulates multilineage differentiation processes of normal tissues remains unkn

226 twork (GRN) regulating the specification and differentiation processes of pigment cells, we experimen

227 mediator AKT1 play a role in the fusion and differentiation processes of rhabdomyosarcoma cells, rep

228 rogress in understanding its precise role in differentiation processes of the mature peripheral immun

229 the epigenetic mechanisms that program this differentiation process on a genome-wide scale are large

230 gonistic factors at low levels, early in the differentiation process or in pluripotent stem cells, co

231 ific to adipogenesis, as another mesenchymal differentiation process, osteoblastogenesis, is enhanced

232 ulate the experimentally observed adipogenic differentiation processes over 15 days in less than 1.5

233 hepatocytes, despite being far along in the differentiation process, possess the capacity for extens

234 cells with cathepsin B inhibitors during the differentiation process reduces cell fusion and bone res

235 biraterone and arises via a reversible trans-differentiation process, referred to as neuroendocrine d

236 Megakaryopoiesis is a 2-step differentiation process, regulated by thrombopoietin (TP

237 Adipogenesis is a key differentiation process relevant to obesity and associat

238 t the downstream target genes regulating the differentiation process remain largely unknown.

239 or populations at intermediate stages of the differentiation process remain to be established.

240 les in the mucosal defense system, but their differentiation process remains poorly understood.

241 however, the molecular mechanism behind this differentiation process remains unclear.

242 This differentiation process required Wt1 expression in this

243 ession during macrophage and oligodendrocyte differentiation, processes requiring membrane growth.

244 liferation of keratinocytes and the terminal differentiation process, resulting in an in vivo-like mo

245 tor requirement controlling each step of the differentiation process, resulting in the production of

246 Live imaging of the differentiation process reveals that cells on the outer

247 me binucleate as they complete the 'terminal differentiation' process soon after birth and are not ab

248 ells are also key participants in the sexual differentiation process, specifically organizing the syn

249 spermatogenesis is an elaborately organized differentiation process, starting with diploid spermatog

250 cell structure, motility, transport and cell differentiation processes such as sporulation, heterocys

251 nonosteoblastic cells without activating the differentiation process, suggesting that its activity is

252 ished by reversing the natural developmental differentiation process, suggesting that the two mechani

253 differences and may arise from activation or differentiation processes taking place in the cells.

254 We have developed a differentiation process that converts human embryonic st

255 marrow myeloid progenitor cells by a complex differentiation process that culminates in fusion of mon

256 hese cells must undergo a targeted, stepwise differentiation process that follows a normal developmen

257 lial-to-mesenchymal transition (EMT) is a de-differentiation process that has been implicated in meta

258 stem cells give rise to all blood cells in a differentiation process that involves widespread epigeno

259 a novel role of iron in modulating a B cell differentiation process that is critical to the generati

260 ell type, called a spore, during a multistep differentiation process that is initiated in response to

261 Endomitosis is a unique megakaryocyte (MK) differentiation process that is the consequence of a lat

262 These data suggest a differentiation process that orchestrates the vasculariz

263 Spermatogenesis is a differentiation process that requires dramatic changes t

264 teins will help to elucidate the presynaptic differentiation process that ultimately leads to synapse

265 standing of the melting, melt-extraction and differentiation processes that intervene between the mag

266 endochondral ossification are the cartilage differentiation processes that lead to skeletal formatio

267 eration of fibroblasts and myofibroblasts by differentiation processes that require extensive alterat

268 g protein 1) that are critical to the B cell differentiation processes that underpin Ab and autoantib

269 Thus, plastids in the SAM undergo distinct differentiation processes that, depending on their linea

270 cells followed by the execution of myogenic differentiation, processes that are coordinated by myoge

271 as levels of E1 remained constant during the differentiation process, the levels of ubiquitin-conjuga

272 st be in part a consequence of shallow-level differentiation processes, though such processes remain

273 II collagen, are degraded at the end of the differentiation process through induction of matrix meta

274 ve B cells and subsequently usurp the B cell differentiation process through the germinal center resp

275 face reconstituted epithelium throughout the differentiation process to 21 days.

276 ce in macrophage activity is the result of a differentiation process to either M1 or M2 phenotypes.

277 r-associated pathogens that usurp the B cell differentiation process to establish life-long latent in

278 ailability, this organism undergoes a simple differentiation process to form cysts that are resistant

279 in actively repressing effector or terminal differentiation processes to promote memory CD8(+) T cel

280 n, it is often necessary to compare multiple differentiation processes triggered by different externa

281 an generate some CD80(+) mTECs in a stepwise differentiation process via YFP(-)Ly51(low)CD80(low) int

282 STAT3 promoted THi development, whereas this differentiation process was greatly impaired in STAT3-de

283 o of Ig L chain usage indicated that a local differentiation process was taking place in arterial wal

284 The role of SOX18 in the differentiation process was validated by using lineage-t

285 the role of Wnt signalling in regulating the differentiation process we manipulated key nodes of this

286 chanisms that orchestrate the stage-specific differentiation process, we developed a computational fr

287 o determine the function of BMP2 during this differentiation process, we employed a primary culture s

288 the function of specific PKC isotypes in the differentiation process, we employed an established mode

289 Here, as a step towards understanding this differentiation process, we report the transcriptional p

290 To assess mechanisms underlying this differentiation process, we searched for muscle specific

291 esponsiveness is set only during the NK cell differentiation process, we transferred mature NK cells

292 At three time points during this differentiation process, we used high-throughput sequenc

293 ling dynamic networks is applicable to other differentiation processes where time-course genome-scale

294 EndMT is an intricate cellular differentiation process whereby endothelial cells detach

295 ls, resulting in defects in cell renewal and differentiation processes which lead to malignancy.

296 ity to receptor-mediated apoptosis along the differentiation process, which becomes the major mechani

297 d glucocorticoid hormones during the cardiac differentiation process, which when coupled with further

298 data provide new insights on the chromoplast differentiation process while enriching our knowledge of

299 tion and de novo occupation occur during the differentiation process, with higher overall nucleosome

300 les to function as molecular switches in the differentiation process without tipping the balance towa