ライフサイエンスコーパス: diffusional

1 g process, involving transcriptional status, diffusional ability of chromatin, and physical interacti

2 at small molecules such as O(2) have similar diffusional access to the complexed HYP in each of the p

3 istal V(H) utilization is thought to involve diffusional access to the recombination centre following

4 ramework for quantifying the contribution of diffusional and biochemical limitations to C(4) photosyn

5 We model both diffusional and conformational fluctuations in a Langevi

6 ute transport near and in the membrane (i.e. diffusional and convective mass transport) is essential.

7 ential for achieving a high throughput rate, diffusional and dissipative dynamical factors must also

8 , while the 'primed' unbound state is highly diffusional and only weakly biased to step towards the M

9 hat could be described with the interplay of diffusional and relaxational kinetics via the Peppas-Sah

10 namical states including epochs of directed, diffusional, and stalled motion.

11 roteins can refine coarse-grain estimates of diffusional anisotropy for adenine nucleotides in the ca

12 these by the model-free formalism with axial diffusional anisotropy further reveal significant ms to

13 ease macromolecular diffusivity and increase diffusional anisotropy in a site-specific manner that de

14 fusivity decreased by 0.16 in all zones, and diffusional anisotropy increased 1.1-fold in the surface

15 of the half-sarcomere further suggests that diffusional anisotropy may lead to modest adenine nucleo

16 ching, to measure diffusion coefficients and diffusional anisotropy of 70 kDa dextran in cartilage du

17 ordered tissues such as articular cartilage, diffusional anisotropy was dependent on site in the tiss

18 oint photobleaching was developed to measure diffusional anisotropy.

19 cular dynamics (MD) simulations and implicit diffusional approaches.

20 enerally uses monoexponential fitting of the diffusional attenuation of pulsed-field gradient stimula

21 he more mature calyx, there is a far smaller diffusional barrier attributable to the highly fenestrat

22 omodulators, the hydrophilic cytosol poses a diffusional barrier for the efficient delivery of AEA to

23 This method uses the design of a diffusional barrier to increase the resolution that can

24 l, a prototypic metabolic sensor, revealed a diffusional barrier within the submembrane space, preven

25 the advancing phagocytic cup by an expanding diffusional barrier.

26 een amply documented and discuss the role of diffusional barriers and other processes in the generati

27 l environment, phosphotransfer systems shunt diffusional barriers and secure regimented signal transd

28 is not well understood, but the existence of diffusional barriers has been proposed.

29 globin solutions, indicating the presence of diffusional barriers in intact cells.

30 nitric oxide, 2) show that extra-erythocytic diffusional barriers mediate most of this effect, and 3)

31 ecific locations on membranes and by forming diffusional barriers that restrict lateral diffusion of

32 by acting as molecular scaffolds and forming diffusional barriers.

33 Previously, a diffusional-based Brownian ratchet mechanism for protein

34 solution, She1 binds tightly to and exhibits diffusional behavior along microtubules.

35 study provides a comparative picture of the diffusional behavior in both environments.

36 Upon degradation of the actin skeleton, the diffusional behavior in the plasma membrane was strongly

37 mparison with unfixed control proteins whose diffusional behavior may or may not differ from that of

38 From the diffusional behavior of nanoparticles in heterogeneous h

39 d scanning electrochemical microscopy due to diffusional blurring, but is crucial to determining the

40 ization occurs at spine heads because of the diffusional bottleneck created by the spine neck.

41 ng step is the diffusion through the aqueous diffusional boundary layer.

42 ake process is diffusion through the aqueous diffusional boundary layer; as such, the overcoated PDMS

43 To overcome the diffusional broadening and have a mobility based resolut

44 k for the quantitative interpretation of the diffusional broadening and the apparent molar mass value

45 er to the electrode, which gives rise to the diffusional broadening of surface features.

46 ovides a high hydrodynamic resolution, where diffusional broadening of the sedimentation boundaries i

47 emporal response and significantly decreases diffusional broadening of the signal in FEEM as compared

48 on mobility spectrometers, in particular (a) diffusional broadening which leads to degradation of ins

49 and t(-1/2), as prescribed for instrumental (diffusional) broadening.

50 heless, and somewhat counterintuitively, the diffusional Brownian motion determines the fundamental l

51 This contribution exceeds that due to diffusional Brownian motion during the passage.

52 lectrolytes to the anodic enzyme and the gas-diffusional cathode design provides the passive supply o

53 lation spectroscopy (FCS) to investigate the diffusional characteristics of functional agonist-occupi

54 local chain conformational properties, local diffusional characteristics, and phase discrimination af

55 of and retract inside the tubules via mainly diffusional Coble creep along the MIEC/metal phase bound

56 cross-linked dimers are formed during random diffusional collisions.

57 Furthermore, the recent observation of diffusional "compartmentalization" has suggested that di

58 n reduced the cytoplasmic, but not membrane, diffusional component of NBD-stearic acid movement 2-fol

59 ep size and direction suggest a considerable diffusional component to its step, which differs from Ki

60 Lung and muscle O2 diffusional conductances were computed from these measur

61 depend on the ratio of the surface and bulk diffusional constants, pK(a) values of surface protolyti

62 ed heterogeneous catalysts are free from the diffusional constraints placed on all known porous solid

63 b initio calculations, taking into account a diffusional contribution according to the encounter pair

64 usion, with evidence favouring modestly more diffusional contribution to delta IPSCs.

65 Diffusional contributions are taken into account using t

66 explained by heterogeneity in spine sizes or diffusional coupling between spines and their parent den

67 We found that spine/dendrite diffusional coupling is heterogeneous and uncovered a cl

68 The regulation of diffusional coupling provides a possible mechanism for d

69 limits for nanocrystal stability by surface diffusional creep and dislocation plasticity, respective

70 n map delineating the predominant regimes of diffusional creep at low stress and high temperature and

71 stalline order and lead to processes such as diffusional creep, sliding and rotation.

72 ndary, rather than grain boundary sliding or diffusional creep.

73 crystal slip serves as a stimulus to surface diffusional creep.

74 esonance method for acquiring and displaying diffusional data that defines highly ordered myofiber pa

75 bly and de novo reassembly model and the non-diffusional displacive model.

76 because it regulates the bioavailability and diffusional distance of endothelial-derived NO.

77 cell densities creating prohibitively large diffusional distances for nutrients.

78 rriers are significant and varied; increased diffusional distances, elevated interstitial fluid press

79 t this cofactor activity is limited to short diffusional distances.

80 kage between coenzyme binding energetics and diffusional domain motion impinges directly on the molec

81 prising odd-even effect in the translational diffusional dynamic properties of n-alkanes in their liq

82 y condition, a source for supplying internal diffusional dynamics.

83 e resultant thin-layer voltammogram shows no diffusional effect, which simplifies the theoretical mod

84 iers, and geometries, as well as kinetic and diffusional effects, providing a tool for hypothesis tes

85 Our measures of diffusional efficiency are shown to decrease as a functi

86 diated PG uptake, cytoplasmic oxidation, and diffusional efflux of the PG metabolite.

87 complementary AFM measurements to probe the diffusional electroactivity of AQDS.

88 tate ion-pair, [C1(2+), I(-)](+*), underwent diffusional electron-transfer oxidation of iodide that d

89 ed reactions (where the rates of the initial diffusional encounter and of structural fluctuations det

90 is indicates that electrostatics control the diffusional encounter but not the dissociation rate, whi

91 m, whereby proteins are pre-aligned in their diffusional encounter by long-range electrostatic attrac

92 ctions of EXO substrates are rate limited by diffusional encounter of enzyme and substrate, explainin

93 itions that are slow on the timescale of the diffusional encounter of noninteracting FAS2 and AChE.

94 We are able to rule out diffusional encounter of O(2) with protein, an outer-sph

95 This value approaches that expected for the diffusional encounter of the enzyme and its substrate.

96 quasi-kinetic search process to emulate the diffusional encounter of two proteins and to identify lo

97 larger cell surface would make recapture by diffusional encounter with the endocytic retrieval machi

98 We propose that before diffusional encounter, the ensemble of accessible confor

99 s by enhancing the rate of success of random diffusional encounters but also play a role in protein f

100 was estimated to be longer than the time for diffusional encounters with other oligomers at typical c

101 did not affect entry of membrane proteins or diffusional entry of small cytosolic proteins.

102 Ions with these short lifetimes are not in diffusional equilibrium with nonsolvent nucleophiles, an

103 Thus, a diffusional event is coupled to the chemical step of Ado

104 structural properties (using stereology) and diffusional exchange characteristics (using measurement

105 is known about the structural development or diffusional exchange characteristics of the Igf2null(+/-

106 cental Igf2 regulates the development of the diffusional exchange characteristics of the mouse placen

107 uctions in its cellular compartments and its diffusional exchange characteristics.

108 nstrate that local synaptic activity reduces diffusional exchange of GluR1 between synaptic and extra

109 aqueous gap junction channels that allow the diffusional exchange of ions and small metabolites betwe

110 When ER topology is altered, the long-range diffusional exchange of proteins in the ER network and t

111 ee STIM1 and Orai1, which engage in constant diffusional exchange with extrajunctional pools.

112 enomena, highlighting proton chemical and/or diffusional exchanges between water and starch.

113 The diffusional exponent (n) values of Peppas equation expla

114 or being affected by the overlapping of the diffusional fields without previous considerations.

115 ffect with the consequent overlapping of the diffusional fields.

116 rofiles in the rock matrix and the estimated diffusional flux from the rock matrix suggest that the e

117 Thermophoresis is the directed net diffusional flux of molecules and colloidal particles in

118 Also the diffusional flux of P as measured with the DGT technique

119 g entropy-driven changes in the directed net diffusional flux of the P(i)-sensor in a temperature gra

120 For demonstration, the diffusional flux through the PETE membrane was character

121 ts total concentration change is dictated by diffusional fluxes into and out of the interface.

122 rge-scale DNA motions through reports of the diffusional freedom of a single fluorophore.

123 lta IPSCs are activated by both synaptic and diffusional GABA.

124 in Au-IO films stems from the generation of diffusional gradients within the pores of the mesostruct

125 show a general approach for rapid control of diffusional growth through nanoparticle self-assembly on

126 unveils and differentiates between nanoscale diffusional heterogeneities of different origins in live

127 cell membrane is heterogeneous and that this diffusional heterogeneity is due to cholesterol's nanosc

128 The detection is based on diffusional hindrance by the insulating objects which al

129 The diffusional hindrance of the glycocalyx along the cell s

130 lons to the tubular ER, as well as for their diffusional immobility and oligomerization.

131 an diffusion in resting receptors but nearly diffusional in active receptors; (iii) whereas resting a

132 f Drosophila early embryos, characterized by diffusional interactions and weak binding, differing fro

133 It was found that diffusional interactions between the tip and the substra

134 icrom above a biological cell, tip-substrate diffusional interactions were greatly diminished at a sc

135 electron acceptor, is kinetically limited by diffusional intermolecular electron transfer, masking th

136 s while extrasynaptic delta subunits mediate diffusional IPSCs and tonic current.

137 pK(a) values, self-assembly equilibria, and diffusional kinetics.

138 of apparent diffusion coefficient (ADC) and diffusional kurtosis (K) were derived by using maximal b

139 was to evaluate the feasibility of employing diffusional kurtosis imaging (DKI) to describe gray matt

140 uctural asymmetry with tractography based on diffusional kurtosis imaging (DKI), which improves upon

141 Diffusional kurtosis imaging (DKI), which measures the n

142 rostructural changes along WM pathways using diffusional kurtosis imaging (DKI).

143 s derived from a two-compartment WM model of diffusional kurtosis imaging (WM-DKI), including intra-a

144 Diffusional kurtosis showed different spatiotemporal dyn

145 h due to influence of neighboring cells, and diffusional lag times.

146 ese signals combine to create spatiotemporal diffusional landscapes that precisely regulate the devel

147 d us to investigate fast reactions up to the diffusional limit including reactions of highly reactive

148 Adipocytes can rapidly reach the diffusional limit of oxygen during growth; hypoxia is th

149 attraction decreases the bundling time to a diffusional limit, which is determined by the capture cr

150 tive to photosynthesis/respiration and CO(2) diffusional limitations can be detected by varying the r

151 raditional methods for encapsulation lead to diffusional limitations imposed by the size of the capsu

152 sopore length, demonstrating that decreasing diffusional limitations leads to increased accessibility

153 Diffusional limitations may reduce the rate of change in

154 but they partially offset their significant diffusional limitations on photosynthesis through their

155 solution value) is observed, consistent with diffusional limitations on substrate access to the enzym

156 ltirate RACiRs may prove useful in assessing diffusional limitations to gas exchange and photorespira

157 combustion reactions place heavy emphasis on diffusional limitations, as reaction scales become comme

158 ty in reactions suffering from steric and/or diffusional limitations.

159 fused membranes is obtained by studying the diffusional lipid dynamics with fluorescence recovery af

160 KPS method, thus facilitating prediction of diffusional loss and penetration of gases and particles,

161 ng of DADMe-ImmH is 50-fold more likely than diffusional loss of the inhibitor from the erythrocyte.

162 apturing inhibitor molecules is greater than diffusional loss to the extracellular space.

163 ed to the microbead forming solution however diffusional losses of riboflavin occurred during the sub

164 -core silica materials providing the shorter diffusional mass transfer path for solutes are less affe

165 The transition between diffusional mass transport and thin-layer regime is desc

166 ower concentrations is chiefly controlled by diffusional mass transport from the solution to the sens

167 ase the quenching is dominated by a dynamic (diffusional) mechanism.

168 The diffusional merge of these oppositely supercoiled domain

169 ivery of molecules into single cells using a diffusional microburet, DMB.

170 Diffusional migration of SSB helps in the local displace

171 uids to diffraction-limited dimensions where diffusional mixing is rapid and efficient.

172 ing time of 12 mul liquids from 170 min, for diffusional mixing, to less than 23 s.

173 recovery after photobleaching to measure the diffusional mobilities of chimeras consisting of green f

174 We then studied the diffusional mobilities of emerin, MAN1, and LBR using fl

175 In cells loaded with excess cholesterol, the diffusional mobilities of GFP-HRas, GFP-NRas, and GFP-KR

176 relamin A called "progerin." We surveyed the diffusional mobilities of nuclear membrane proteins to i

177 Consistent with this finding, the diffusional mobilities of tumor-derived sequence-specifi

178 studied their intracellular localization and diffusional mobilities using fluorescence recovery after

179 R3 mobility may be higher than its intrinsic diffusional mobility because of additional ATP- and micr

180 of the attendant, radically enhanced, atomic diffusional mobility inside actively deforming shear ban

181 , our results suggest that the regulation of diffusional mobility is induced by a reduction in cell v

182 ion and/or aggregation, we have measured the diffusional mobility of green fluorescent protein (GFP)

183 We measured the diffusional mobility of human CFTR in the plasma membran

184 lesterol loading) had similar effects on the diffusional mobility of raft and nonraft proteins.

185 Accelerated diffusional mobility of raft-associated lipids was shown

186 onded to ER cholesterol changes with altered diffusional mobility, suggesting that erlins themselves

187 he reactive surfaces and a decrease in their diffusional mobility.

188 clear mRNP trafficking are consistent with a diffusional model.

189 terahertz region, where the higher frequency diffusional modes are strongly overlapped with libration

190 n switching K5s between force generation and diffusional modes of MT binding.

191 ge number of contributions ranging from slow diffusional modes to underdamped librations and intramol

192 ng profiles, as they would be obliterated by diffusional morphodynamics.

193 eins, many MT-binding proteins seem to adopt diffusional motility as a transportation mechanism.

194 -headed KIF1A was reported to undergo biased diffusional motion along microtubules.

195 observed sizes for confinement of chromatin diffusional motion are similar to the estimated sizes of

196 th the principle of thermophoresis, i.e. the diffusional motion of particles in response to a tempera

197 cted by the mutations is indeed the relative diffusional motion of the domains.

198 Conversely, at faster scan rates the diffusional motion of the molecule limits the simulated

199 The diffusional motion on the membrane, characterized by sin

200 Diffusional motion within the crowded environment of the

201 he relative contributions of vibrational and diffusional motion.

202 systems also exhibit dissimilar traits when diffusional motions and residence times of single constr

203 Large, diffusional motions are often on timescales that are dif

204 t upper limit to folding speed once the bulk diffusional motions become sufficiently rapid.

205 The speed of simple diffusional motions, such as the formation of loops in t

206 ction, which limits opportunities to observe diffusional motions.

207 This observation of diffusional movement of a protein on ssDNA introduces a

208 e synapse, spontaneous activity confines the diffusional movement of GluR1 to restricted subregions o

209 tail-microtubule binding may also influence diffusional movement of kinesin-1 on microtubules, and k

210 errupted with frequent directional switches, diffusional movement, and pauses.

211 We also observed significant diffusional noise of G-actin monomers, which leads to sm

212 ions demonstrate that under these conditions diffusional overlap between neighboring SWNTs is signifi

213 onal solid metal UMEs (e.g., Pt, Au), due to diffusional overlap between neighboring SWNTs.

214 ogically consequential in contexts where the diffusional path of oxygen is not water dominated.

215 tudies were conducted to determine whether a diffusional pathway for solutes exists from the ciliary

216 consistent with the existence of an anterior diffusional pathway in the human eye.

217 e mesoporous zeolitic materials that combine diffusional pathways on two different size scales.

218 eld glued bilayers of 2 and 3 having similar diffusional pathways, as judged by He/N2 selectivities.

219 en transversal and longitudinal sarcoplasmic diffusional pathways.

220 ution by reducing the detrimental effects of diffusional peak broadening and increasing peak widths.

221 True water diffusional permeability (2.7 +/- 0.4 microm/s) is shown

222 shown to be 39 +/- 6% greater than apparent diffusional permeability for 8 oocytes.

223 omoter (P0) regulates the development of the diffusional permeability properties of the mouse placent

224 vesicles showed that glucagon increased the diffusional permeability to the ammonia analog [(14) C]m

225 late intracellular lifetime to true membrane diffusional permeability.

226 s suggest that HIV maturation involves a non-diffusional phase transition in which the detaching laye

227 s application owing to its dependence on the diffusional potentials of inorganic ions.

228 For example, the promotion of diffusional problems (e.g., pH gradients, substrate or p

229 However, to establish what diffusional process is the bottleneck for Li-ion transpo

230 displacive deformation, is accomplished via diffusional process mainly, due to the high homologous t

231 Because the rate of a diffusional process such as protein folding is controlle

232 h the TiO(2)-anatase crystal, an anisotropic diffusional process that can be up to an order of magnit

233 nding proteins, and intra- and intercellular diffusional processes.

234 ke by cells most likely arises from passive, diffusional processes.

235 Measurements of diffusional properties as a function of viscosity and pr

236 cal conductivity to link the latter with the diffusional properties of TATS.

237 imaging to characterize the organization and diffusional properties of the PM in the early embryonic

238 valuate, quantify and map heterogeneities in diffusional properties within complex hierarchically por

239 es are known to affect protein stability and diffusional properties.

240 lso been developed to elucidate chemical and diffusional proton exchange phenomena, and to improve th

241 del compound, trimethylpyruvate, to act as a diffusional quencher of indole fluorescence in solution.

242 The first involves diffusional quenching of the excited state by Br(-) with

243 decomposition of the current into transient diffusional, radial convectional, and axial convectional

244 s 10 times that for alpha-D-glucose, and the diffusional rate constants should be essentially the sam

245 ibe new, molecular-surface-based models, for diffusional reaction boundary criteria and compare resul

246 ferritic alloy, is effective in reducing the diffusional relaxation along the interface between the p

247 We also constrain the molecular diffusional resistance above the ocean surface-an import

248 xidative phosphorylation, increased cellular diffusional resistance and inhomogeneities in oxygen sup

249 alculated charge transfer resistance and the diffusional resistance components is evaluated.

250 hifts in both charge transfer resistance and diffusional resistance.

251 ith the significant coupling between overall diffusional rotation and internal motion expected to exi

252 line array of molecular rotors with inertial diffusional rotation at the nanoscale, characterized by

253 dynamics simulations, indicate that inertial diffusional rotation is characterized by a broad range o

254 fusion of the whole gA dimer, giving rise to diffusional rotation of the dimer about the channel axis

255 th and direction, diffusion sensitivity, and diffusional sampling to determine the optimal achievable

256 In such a membrane-dominated diffusional scheme, the influence of cholesterol on oxyg

257 The strength of diffusional screening is also related to the number of c

258 er relationship supports our hypothesis that diffusional screening is present in this system.

259 o determine whether and if so to what extent diffusional screening may operate in placental villi.

260 le-attached head, the other head undergoes a diffusional search for its next site, the outcome of whi

261 on polymeric surfaces as a means to expedite diffusional search processes in molecular engineered sys

262 al intermediates and reduce the dimension of diffusional search represents a novel and effective mech

263 how Rad4 pauses to recognize lesions during diffusional search, we examine conformational dynamics a

264 within the contact pair becomes slower than diffusional separation (k(-d)), causing deviation from t

265 reaction goes against this proposal, as the diffusional separation of CO(2) would be on the order of

266 ay channel for the geminate radical pairs is diffusional separation to free radicals.

267 associated with covalent bond formation and diffusional separation to the solvent-separated ion pair

268 ates of variable size that segregated due to diffusional sieving of small, mobile M1-AQP4-enriched ar

269 ement this strategy in a native microfluidic diffusional sizing platform, allowing us to achieve dete

270 However, it does not address the diffusional spread of the reaction boundary from the cos

271 ecules that rapidly switch between different diffusional states.

272 duct reprotonation, respectively, and that a diffusional step, such as substrate binding, may be rate

273 formation/disruption cycles with intervening diffusional steps result in larger DNA loops, leading to

274 Store microanatomy suggests that diffusional strictures may account for this paradox.

275 n of antibiotics in the soil solution, their diffusional supply, and the exchange kinetics between di

276 Herein, we demonstrate that diffusional surface voltammetry (DSV), which embodies fi

277 These Munc18-1 and syntaxin-1A diffusional switches were blocked by the expression of M

278 ional static hybridization, which depends on diffusional target delivery, with signals obtained in a

279 The mean diffusional time constant of the wild type and variants

280 of the pH oscillations was smaller than the diffusional timescale of the particles, whereas disorder

281 nctions at the MEJ was assessed by measuring diffusional transfer of biocytin and Cy3.

282 The ion exchange reaction occurs through diffusional transfer of molecules between the ion exchan

283 lly with the tubulin COOH terminus to permit diffusional translocation of MCAK along the surface of M

284 t the measured permeability is controlled by diffusional translocation of probe molecules through wat

285 need to explicitly account for kinetics and diffusional transport (and localization) of enzymes, sub

286 thin such arrays has a significant impact on diffusional transport as the pore size is reduced to the

287 port by Si transporters at low Si(OH)(4) and diffusional transport controlled by the capacity of intr

288 key limiting factors of filopodial length is diffusional transport of G-actin monomers to the polymer

289 These findings suggest that diffusional transport of macromolecules is anisotropic i

290 oscope (SECM-AFM) has been used to probe the diffusional transport of target electroactive solutes in

291 response controlled by the nanopore-mediated diffusional transport of tetrabutylammonium ions to the

292 hought to be much too large to undergo rapid diffusional transport through mucus barriers.

293 The CHM benefits from counter-diffusional transport within the hydrogel, where H(2) di

294 ng sedimentation fluxes with periods of high diffusional transport.

295 can be exchanged across the gel scaffold by diffusional transport.

296 maller than the value predicted for a purely diffusional transport.

297 a nanoscale arrangement that supports rapid diffusional transport.

298 Our data suggest that diffusional trapping through protein-protein interaction

299 osmotic fragility of infected cells based on diffusional uptake via PESAC and the two-compartment geo

300 40% compared with WT), and no change in the diffusional water permeability (P(d)).