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1  PI(4,5)P(2) (triglycine) and PI(3,4,5)P(3) (diglycine).
2 te of S. aureus sortase SrtA is specific for diglycine.
3                        The autohydrolysis of diglycine-activated succinic esters and drug conjugates
4     As an example of rapid autohydrolysis of diglycine-activated succinic esters for instant cellular
5 iglycine favors intramolecular hydrolysis of diglycine-activated succinic esters to promote autohydro
6          Specifically, autohydrolysis of the diglycine-activated succinic esters turns the nanofibers
7 ated and identified by LC-ESI-MS as catechol-diglycine adduct that undergoes polymerization with othe
8 cine adopt zwitterionic structures, sodiated diglycine adopts a salt-bridge form, and sodiated trigly
9 tides containing lysine residues modified by diglycine, an adduct left at sites of ubiquitination aft
10 of a sulfonated tryptic peptide containing a diglycine branch generates a unique spectrum composed of
11 s of one glycine residue from the sulfonated diglycine branch) that can directly reveal the amino aci
12 on of ubiquitin-conjugated proteins produces diglycine branched peptides containing the modification
13        Signature fragments distinguished the diglycine branched peptides from other modified and unmo
14 on of ubiquitin conjugated proteins produces diglycine branched peptides in which the C-terminal Gly-
15 ner, but several fragments characteristic to diglycine branched peptides were observed under low coll
16 ation based on the N-terminal sulfonation of diglycine branched peptides.
17 lc4a1 gene replaced with sequence encoding a diglycine bridge.
18                                 Using global diglycine-capture (K-GG) proteomics, we found here that
19 olvation) free energies of (Gly)n and cyclic diglycine (cGG) and analyze the data according to experi
20 ilized a monoclonal antibody that recognizes diglycine (diGly)-containing isopeptides following tryps
21           Similar results were found for the diglycine dimer.
22  the polyglycine acceptor nucleophile beyond diglycine does not further enhance the binding and catal
23  Here we show that succinic ester-containing diglycine drastically boosts the cellular uptake of supr
24                     Sodiated monoglycine and diglycine exchange via an onium-ion mechanism.
25  resonance (NMR) suggests that a "U-turn" of diglycine favors intramolecular hydrolysis of diglycine-
26         Herein, we report that conjugating a diglycine (GG) to an antibiotic prodrug drastically acce
27 ly after a conserved internal ubiquitin-like diglycine (Gly-Gly) motif.
28 gous label that is chemically similar to the diglycine (GlyGly) tag, which is left at the ubiquitinat
29 elix, which alters bending and rotation at a diglycine hinge connecting the dimerization and cleavage
30 g two identical fragments head-to-tail using diglycine increases the proportion of cylindrin-sized ol
31 ipitation using an antibody specific for the diglycine-labeled internal lysine residue indicative of
32                                            A diglycine linker recognition site (Gly-Gly-Ile-Glu-Gly-A
33  chelate on biodistribution, mercapto-acetyl diglycine (MAG(2)) was compared with diethylenetriaminep
34  whose products are required for glycine and diglycine modification of lipid A.
35                           Antibodies against diglycine-modified alpha-synuclein peptides confirmed th
36     We use mass spectrometry to identify 374 diglycine-modified lysines on 236 ubiquitinated proteins
37 e C-terminal amino acid residues following a diglycine moiety on a small sulfur carrier protein, and
38 ion of the BK S6 alpha-helix from the unique diglycine motif at the position of the Kv hinge glycine.
39 one dynamics, indicate a bending motion at a diglycine motif connecting dimerization and cleavage reg
40                  This required the conserved diglycine motif in the carboxyl terminus of ISG15.
41          These data indicate that the unique diglycine motif in the GRP1 PH domain, as opposed to the
42 ve-site cysteine of E1-L2 and the C-terminal diglycine motif of FAT10.
43 nds exclusively to the unanchored C-terminal diglycine motif of ubiquitin instead of conjugated polyu
44 s a deep binding pocket where the C-terminal diglycine motif of ubiquitin is inserted, thus explainin
45  with a beta-grasp fold and carboxy-terminal diglycine motif similar to ubiquitin, that form protein
46 n-binding domain (UBD) binds free C-terminal diglycine motifs of unanchored ubiquitin polymer chains
47  Recently, we have shown that conjugation of diglycine of CLsu (CLsuGG) not only increases the antibi
48 entified protein fragments are terminated by diglycine or glycylalanine, the preceding amino acids ar
49 n)() for the peptides dialanine (P = AA) and diglycine (P = GG).
50 ecognize tryptic peptides with an N-terminal diglycine remnant, corresponding to sites of N-terminal
51 y the lipid A anchor of LPS with glycine and diglycine residues.
52 med UbR74) and its ubiquitinated form with a diglycine tag (UbR74-GG).
53 e of these factors varies with ion size from diglycine to a 1 mum oil droplet.
54 orm localizes to the plasma membrane and the diglycine to the leading edge.
55 ntibodies do not recognize isopeptide-linked diglycine (ubiquitin) modifications on lysine.
56 ne, L-leucine, L-lysine, L-glutamic acid, or diglycine with L-serine as a major component.