ライフサイエンスコーパス: diisopropyl

1 2,9-dimethyl-1,10-phenanthroline; dipp = 2,9-diisopropyl-1,10-phenanthroline (dipp); tfpb(-) = tetrak

2 ethyl-(1-heptenyl)silanol ((E)-1) and of (E)-diisopropyl-(1-heptenyl)silanol ((E)-2) with 2-iodothiop

3 Single-crystal X-ray diffraction analysis of diisopropyl 2-iodoxyisophthalate 6b showed intramolecula

4 erocyclic carbene, SIAr(Me,iPr) (1,3-bis(3,5-diisopropyl-2,6-dimethylphenyl)-2-imidazolidinylidene; a

5 which are nonnucleophilic bases, 4-ethyl-2,6-diisopropyl-3,5-dimethylpyridine (4) is also such a base

6 ative aldehyde (the "monomeric" aldehyde) is diisopropyl-3-formyl-4-(2-methylprop-1-enyl)cyclopent-3-

7 -diquinolyl)naphthalene, 2, and 1,8-bis(2,2'-diisopropyl-4,4'-diquinolyl)naphthalene, 3, in 42% and 4

8 -diquinolyl)naphthalene, 8, and 1,8-bis(2,2'-diisopropyl-4,4'diquinolyl)naphthalene N,N'-dioxide, 9,

9 SiN(Dipp) )], where L=carbene=NHC(iPr) (N,N'-diisopropyl-4,5-dimethyl-2-ylidene) and (Me2) CAAC (1-(2

10 Reaction of 1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene (NHC) with 2

11 The N-heterocyclic carbene 1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene (Pr(i)2NHCMe2

12 ) = +11.8 kcal/mol is found when the NHC 1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene is employed a

13 4,6-triisopropylphenyl, NHC(iPr2)(Me2) = 1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene) is obtained

14 Pr(2)Me(2))(4)H](+) (1, I(i)Pr(2)Me(2) = 1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene) with oxygen

15 (Pr(i)(2)NHCMe(2) = C(11)H(20)N(2) = 1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene).

16 ides [(NHC)Al(Tipp)-mu-Ch](2) (NHC=IiPr (1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene, IMe(4) (1,3,

17 2)] (R = 2,4,6-triisopropylphenyl; NHC = 1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene; COD = 1,5-cy

18 ine-2,6-dicarboxamide, (NO2)L = N,N'-bis(2,6-diisopropyl-4-nitrophenyl)pyridine-2,6-dicarboxamide), a

19 ore in the complexes LCuOH (L = N,N'-bis(2,6-diisopropyl-4-R-phenyl)pyridine-2,6-dicarboxamide, R = H

20 es: see text] The diradical methylenebis(1,5-diisopropyl-6-oxoverdazyl) was synthesized by benzoquino

21 Diethyl (7, MRS4084) and diisopropyl (8, MRS4074) phosphotriesters were highly pr

22 '-diacridyl)naphthalene, 2, and 1,8-bis(4,4'-diisopropyl-9,9'-diacridyl)naphthalene, 3, did not show

23 tion-state structure of THF solvated lithium diisopropyl amide (LDA) in hydrocarbon solvent was chose

24 3)C(6)H(4)CH(2)Br in the presence of lithium diisopropyl amide at -78 degrees C in THF.

25 Treating 2-methyl-3-acylindoles with lithium diisopropyl amide leads to the elimination of a proton f

26 ating 2-methyl-3-benzoylindoles with lithium diisopropyl amide leads to the elimination of a proton f

27 te consisting of pinacolone enolate, lithium diisopropyl amide, lithium oxide, and HMPA in the ratio

28 d for the N,N-diethyl amides 5a than the N,N-diisopropyl amides 5b.

29 complex [Ag(BAC)(2)][CO(2)CF(3)] (BAC = bis(diisopropyl)aminocyclopropenylidene) is reported.

30 h a general difunctionalization using simple diisopropyl azodicarboxylate (DIAD) as a radical trap.

31 ol in the presence of triphenylphosphine and diisopropyl azodicarboxylate (DIAD) is utilized to prepa

32 nmoser's salt, Togni's reagent, Selectfluor, diisopropyl azodicarboxylate (DIAD), MeSX) in high regio

33 riphenylphosphine (Ph(3)P) with an excess of diisopropyl azodicarboxylate at 0-25 degrees C resulted

34 fferent solvents (acetonitrile, benzene, 1,3-diisopropyl-benzene) for the charge separation and the c

35 Ortholithiation of 3-fluorophenyl-N,N-diisopropyl carbamate by lithium diisopropylamide (LDA)

36 oates (TIB esters) and secondary dialkyl N,N-diisopropyl carbamates have been reported to be resistan

37 roxy phosphonic acid mono methyl esters with diisopropyl carbodiimide at ambient temperature leads to

38 on a cyclopropyl derivative of Bingel and a diisopropyl cyclohexyl C60 alcohol (4a) as synthesized b

39 With N,N-bis(2,6-diisopropyl)dihydroimidazolium chloride (10) as the liga

40 ermosalient transformation in nickel(II) bis(diisopropyl)dithiocarbamate has been investigated using

41 Diisopropyl ester 16 (MRS2978) of (1'S,2'R,3'S,4'R,5'S)-

42 The dimethyl and diisopropyl esters of 2-iodoxyisophthalic acid were prep

43 that acetonitrile, (S)-BINAPO (5 mol %), and diisopropyl ether (4.00 equiv) can catalyze the chlorina

44 liter-scale solvent extraction process using diisopropyl ether (DIPE) is routinely performed at the U

45 Radicals derived from dioxane and diisopropyl ether by flash photolysis of DTBP in etherea

46 ther volatile anesthetics, diethyl ether and diisopropyl ether, reduce the quenching caused by haloth

47 lic carbene (NHC)-boranes in the presence of diisopropyl ethyl amine provided about three dozen stabl

48 inhibitors phenylmethylsulfonyl fluoride and diisopropyl fluoride were found to have a profound effec

49 ed by both phenylmethylsulfonyl fluoride and diisopropyl fluoride.

50 FXIa(G193E) inhibition by diisopropyl fluoro-phosphate was approximately 30-fold s

51 exclusive substrate specificities, PON1 and diisopropyl fluorophosphatase (DFPase) have essentially

52 Purified PKA was blocked by diisopropyl fluorophosphate (1 mm), phenylmethylsulfonyl

53 Diisopropyl fluorophosphate (DFP) causes neurotoxicity r

54 ates with challenging leaving groups such as diisopropyl fluorophosphate (DFP) or venomous agent X, c

55 The irreversible AChE inhibitor diisopropyl fluorophosphate (DFP) usually caused a susta

56 Diisopropyl fluorophosphate (DFP) was used as a nerve ga

57 The addition of a CE inhibitor, diisopropyl fluorophosphate (DFP), to mouse serum in vit

58 l phosphoproteins evoked by the OP compound, diisopropyl fluorophosphate (DFP).

59 of the nerve agent organophosphate substrate diisopropyl fluorophosphate (DFP).

60 erties of thrombin by hirudin and trypsin by diisopropyl fluorophosphate abolished the observed RhoA

61 4-(2-aminoethyl)benzenesulfonyl fluoride and diisopropyl fluorophosphate completely inhibited Abeta d

62 the partial inhibition of enzyme activity by diisopropyl fluorophosphate or phenylmethylsulfonyl fluo

63 All enzymes were inhibited by diisopropyl fluorophosphate, a general serine class inhi

64 The enzyme was inhibited by diisopropyl fluorophosphate, a general serine class inhi

65 Diisopropyl fluorophosphate, a transition-state analog i

66 Seprase could be affinity-labeled by [3H]diisopropyl fluorophosphate, but the proteolytically ina

67 e agents, including celecoxib, rofecoxib and diisopropyl fluorophosphate, demonstrate a distribution

68 peptides with a serine proteinase inhibitor, diisopropyl fluorophosphate, indicated that they were ac

69 factor to achieve deactivation, 5 x 10(-7) M diisopropyl fluorophosphate, or the neutrophil immobiliz

70 Diisopropyl fluorophosphate, which inhibits NTE esterase

71 y inhibited by the serine esterase inhibitor diisopropyl fluorophosphate, which specifically and stoi

72 14C-Diisopropyl fluorophosphate-radiolabeled CM from MP24.15

73 nctional and bound the active-site inhibitor diisopropyl fluorophosphate.

74 d by the classical serine protease inhibitor diisopropyl fluorophosphate.

75 ked by serine-protease inhibitors, including diisopropyl fluorophosphate.

76 njection of the sarin nerve agent surrogate, diisopropyl fluorophosphate.

77 roteinase domain, which was labeled by [(3)H]diisopropyl fluorophosphate.

78 pecific for thrombin (reversed with inactive diisopropyl-fluorophosphate [DFP]-thrombin) and mediated

79 The native structure and a complex with diisopropyl fluorophosphonate (DFP, a potent serine hydr

80 In contrast, the substrate specificity for diisopropyl fluorophosphonate (P-F bond) was substantial

81 ion of GlpG with 3,4-dichloroisocoumarin and diisopropyl fluorophosphonate, both mechanism-based inhi

82 ture of the covalent adduct between GlpG and diisopropyl fluorophosphonate, which mimics the oxyanion

83 ptin, angiotensin II, bradykinin, anti-PRCP, diisopropyl-fluorophosphonate (DFP), phenylmethylsulfony

84 Sequence data and 3H-diisopropyl fluorphosphate labeling results suggest that

85 emonstrate that the conformations of the N,N-diisopropyl groups in the amide moiety of 2 have a large

86 alence (ESMV) occurs in the 1,2-diphenyl-1,2-diisopropyl hydrazine radical cation, a molecule in whic

87 nd intravenously administered technetium 99m diisopropyl-imino-diacetic acid were imaged simultaneous

88 ly available N-alkyl- and N-aryl-substituted diisopropyl iminomalonates and a wide range of soft anio

89 ns of the group transfer radical reaction of diisopropyl iododifluoromethylphosphonate onto carbohydr

90 opyl ketone > t-Bu-C( horizontal lineO)-Ph > diisopropyl ketone >> t-Bu2C horizontal lineO > ClSiMe3

91 ldithiophosphate complexes were eluted using diisopropyl ketone prior to atomization.

92 Typical examples are di-n-propyl and diisopropyl ketones (both of which produce CH(3)CH=OCF(3

93 < trans-2,3-dipropyl approximately trans-2,3-diisopropyl < cis-hexamethylene.

94 ity measurements of acetone, eucalyptol, and diisopropyl methanephosphonate.

95 tituted PTE upon addition of two inhibitors, diisopropyl methyl phosphonate and triethyl phosphate, a

96 In the case of the PTE-diisopropyl methyl phosphonate complex, the phosphoryl o

97 or acetonitrile, dimethyl methylphosphonate, diisopropyl methyl phosphonate in positive polarity and

98 tructure of PTE complexed with the inhibitor diisopropyl methyl phosphonate, which serves as a mimic

99 Two nerve agent simulants, diisopropyl methylphosphonate (DIMP) and di-methyl methy

100 of protonation on the nerve agent simulants diisopropyl methylphosphonate (DIMP) and dimethyl methyl

101 ical warfare agent (CWA) surrogate compound, diisopropyl methylphosphonate (DIMP), demonstrated that

102 l phosphate, dimethyl methylphosphonate, and diisopropyl methylphosphonate were captured by passing a

103 Diisopropyl methylphosphonate, GB impurity, was not reco

104 eridine moiety with either N,N-dipropyl, N,N-diisopropyl, N,N-dibutyl, p-methylpiperidine, or N,N-bis

105 ution reactions of N-Boc-pyrrolidine and N,N-diisopropyl-o-ethylbenzamide were performed using these

106 tentorin (1,3,4,6,8,10,11,13-octahydroxy-2,5-diisopropyl-phenanthro[1,10,9,8,o,p,q,r,a]per ylene-7,14

107 Propofol (2,6-diisopropyl phenol), a widely used systemic anesthetic,

108 olin-2-ylidene; Py = pyridine; IPr = 1,3-bis(diisopropyl)phenylimidazol-2-ylidene; dbabh = 2,3:5,6-di

109 dbabhNO (10) (Mes = mesityl; SIPr = 1,3-bis(diisopropyl)phenylimidazolin-2-ylidene; Py = pyridine; I

110 ntly bound transition state analog inhibitor diisopropyl phosphate (DIP).

111 ntaining compounds (diphenylphosphine oxide, diisopropyl phosphite, phosphine-borane complexes, and t

112 Diisopropyl phosphofluoridate (DFP) at high concentratio

113 ate hydrolase, with the ability to hydrolyze diisopropyl phosphofluoridate and other nerve agents.

114 methyl]-3-methylpseudouridine-3'-(methyl-N,N-diisopropyl)phosphoramidite, is reported.

115 Diisopropyl phosphorofluoridate (DFP) is an organophosph

116 Diisopropyl phosphorofluoridate (DFP) produces organopho

117 reaction of Cl2(*-) with the model compound diisopropyl phosphorothioate.

118 ompounds resulting in dimethyl, diethyl, and diisopropyl phosphoryl adducts have been monitored with

119 Starting material N-(O,O-diisopropyl phosphoryl)-trans-4-hydroxy-L-proline is con

120 pared in one step by reductive alkylation of diisopropyl phthalate (Na/THF, followed by the appropria

121 repare complex fused- or spiro-bicycles from diisopropyl phthalate in just one or two steps.

122 t contain a new TREN-based ligand [(3,5-(2,5-diisopropyl-pyrrolyl)(2)C(6)H(3)NCH(2)CH(2))(3)N](3-) ([

123 0 laboratory steps mediate the conversion of diisopropyl squarate to (+/-)-hypnophilin (8).

124 tained even when both substrates include 2,6-diisopropyl substituents.

125 l substitutions on silicon, the dimethyl and diisopropyl, were examined.