ライフサイエンスコーパス: dimer

1 valent H-type BODIPY aggregate, namely, an H-dimer.

2 er dissociation leading to less stable Rad50 dimer.

3 53 binds initially to cognate DNA sites as a dimer.

4 ragment directly binds a CENP-C cupin domain dimer.

5 pe aggregates, was also encapsulated as an H-dimer.

6 rom that of the previously reported Fab 2G12 dimer.

7 ter molecules sequentially bond to the sugar dimer.

8 ually results in parallelization of integrin dimer.

9 cal and charge transfer excitons within each dimer.

10 tion in the underlying non-Hermitian quantum dimer.

11 ith a molecular catalyst of vanadium (V)-oxo dimer.

12 cket is located at the interface of the NfoR dimer.

13 guration similar to the antiparallel (lower) dimer.

14 the first merocyanine oligomer longer than a dimer.

15 ) model describing a 1D chain of interacting dimers.

16 ity functional theory calculations of flavin dimers.

17 erization to give surface-bound, oxo-bridged dimers.

18 remains elusive in the context of regulating dimers.

19 ization is necessary to create activated Raf dimers.

20 n-dynactin complexes that contain two dynein dimers.

21 en focused only on a limited number of small dimers.

22 "GTP cap" that consists of GTP-bound tubulin dimers.

23 ragments capable of forming RNase-protecting dimers.

24 0% phosphorylation of the available sites in dimers.

25 characterized by unstable interfaces between dimers.

26 th apical and as bridging sites in phosphate dimers.

27 sidered critical for back-to-back binding of dimers.

28 single-bonded 3-phenyl-2H-1,4-benzothiazine dimer 2 to the Delta(2,2('))-bi(2H-1,4-benzothiazine) sc

29 e protein (198 vs. 107 mg/L, P = .010) and D-dimer (8.6 vs. 2.1 ug/mL, P = .004) levels, and lower na

30 on, Fab HC84.26.5D exists predominantly as a dimer (~80%) in equilibrium with the monomeric form of t

31 orrectly replicating T-containing pyrimidine dimers, a phenomenon known as the 'A-rule'.

32 nidins-rich fraction after thioglycolysis, a dimer A2-ext and a molecule that corresponds to a linkag

33 c field-dependent phthalocyanine monomer and dimer absorption spectra.

34 Furthermore, addition of preformed dimers accelerates the aggregation reaction of monomers.

35 Hexafluoropropylene oxide-dimer acid (HFPO-DA), a replacement compound for perfluo

36 T (SHR)/SCARECROW (SCR) transcription factor dimer activates CYCLIND6;1 (CYCD6;1) to drive formative

37 ting protein (GAP) complex, and prevents Rag dimer activation during amino acid starvation.

38 st, smoking history, sex and the levels of D-dimer among two groups.

39 maximum of the carotenoid bound by the CCP2 dimer and a further 10 nm shift in the tetramer form.

40 ven healthy volunteers and correlated with D-Dimer and CTOI.

41 n photoperiodic conditions that incorporates dimer and monomer photoreception, dimer/monomer cycling,

42 Elevated admission D-dimer and peak D-dimer were associated with venous throm

43 sively interacts with the ATP-dependent FlhG dimer and stimulates FlhG ATPase activity.

44 lity of residues in the linker region and of dimer and trimer interfaces.

45 AncFMO1 crystallized as a dimer and was structurally resolved at 3.0 angstrom reso

46 only by a factor of 3 to 4 for proton-bound dimers and 3 for the proton-bound 1-octanol trimer.

47 cluster-transfer reactions between the holo-dimers and apo-ferredoxin (FDX2) are monitored, and inte

48 receptor 2, as heavy chains to form antibody dimers and Fab heavy chains to form Fab tetramers.

49 lay quaternary-structure epitopes found on E dimers and higher-order structures that form the viral e

50 GNIFICANCE STATEMENT Visual arrestin-1 forms dimers and tetramers.

51 erved transient accumulation of a decamer-of-dimers and the appearance of 90-dimer capsids.

52 We found that quercetin glycosides, dimers and trimer in OP-bread, determined according to t

53 at least reliably distinguish monomers from dimers and trimers.

54 embles to form a hexamer that is composed of dimers and trimers.

55 production of fibrin degradation products (D-dimer) and consumption of platelets.

56 le state with elevated C-reactive protein, D-dimer, and ferritin.

57 er age; elevated C-reactive protein (CRP), D-dimer, and fibrinogen levels; tachycardia; thrombocytosi

58 s mellitus, higher body mass index, higher d-dimer, and greater severity of hypoxemia on ICU admissio

59 crystal structures of the M204-scFv monomer, dimer, and trimer revealed conformational differences th

60 Elevated levels of C-reactive protein, d-dimer, and troponin were found in 100%, 91%, and 71% of

61 s of signal transduction mediated by GABA(B) dimers, and have important implications for rational dru

62 states from monomers to dimers, oligomers of dimers, and randomized polymer structures before being u

63 ) of avidin tetramers into compact monomers, dimers, and trimers with cross sections consistent with

64 coagulation exacerbation as fibrinogen and D-dimers, and were increased in patients requiring invasiv

65 FXIII-A-subunits that stabilize the FXIII-A2 dimer are not fully understood.

66 s form a core to which the catalytic subunit dimers are attached, adopting the shape of a Maltese cro

67 ndrical protein polymers composed of tubulin dimers are key components of the cytoskeleton.

68 ns such as UV-induced cyclobutane pyrimidine dimers are removed from the genome by concerted dual inc

69 y target genes that are activated by MYC:MAX dimers are repressed by MNT:MAX dimers, MNT is considere

70 ins that bind DNA nonspecifically, like H-NS dimers, are expected to fail with this respect.

71 s lacking key pharmacophoric residues in one dimer arm retaining high antagonist affinity.

72 "Closing" of dimers around clients is regulated by ATP binding, co-ch

73 eta strand configuration in an excited-state dimer, as well as exchange of both monomer and dimer spe

74 in association is very short-ranged: the two dimers associate rapidly within tens of nanoseconds when

75 ia, and elevation in inflammatory markers, D-dimer, B-type natriuretic peptide, IL-6, and IL-10 level

76 uggest the potential for implementation of D-dimer based protocols to reduce low-yield CTPA ordering.

77 have used the ExoY structure to construct a dimer-based structural model for the ExoY-F-actin comple

78 y pair of these CB[8]-secured Pt(II) complex dimers bearing different tpy "heads" and thiolate "tails

79 the relative level of uncompressed (GMPCPP) dimers, beginning at approximately 20% incorporation.

80 ng monomers and dimers in solution, but only dimers bind and activate STING.

81 ybrid res sites containing both Tn3 and Bart dimer binding sites.

82 erface involving resolvase NTDs at all three dimer-binding sites in res.

83 e triplet-triplet exchange (J) for tetracene dimers, bipentacene, a subunit of the benzodithiophene-t

84 Interestingly, the dimer-bleomycin conjugate cleaves the entire pri-miR-17-

85 e observed that the enzyme crystallizes as a dimer but remains monomeric in solution.

86 Both proteins bind to Psi RNA primarily as dimers, but to a control RNA primarily as monomers.

87 cytokinin trans-zeatin riboside, procyanidin dimer, caffeoylshikimic acid and trihydroxy-octadecenoic

88 have shown that on certain substrates, water dimers can diffuse more rapidly than water monomers.

89 Consequently, D-dimer cannot be used to exclude DVT without an assessmen

90 hepatitis B capsid protein dimers to the 120-dimer capsid.

91 a decamer-of-dimers and the appearance of 90-dimer capsids.

92 n protein MLX (MLX), and MNT-MLX and MNT-MAX dimers co-exist.

93 when the IF-TTF unit is incorporated into a dimer, compared to a monomer analogue.

94 esented as monomers and not in their natural dimer configuration.

95 ructural analyses indicate that the dimer-of-dimers configuration represents an inactive state of DUO

96 he latter value is typical of DDD-AAA H-bond dimers, consistent with proton transfer across the centr

97 The simplest form, Hp 1-1, forms dimers consisting of two alpha1beta units, connected by

98 ional studies show that both the tetramer-to-dimer conversion of TrkA and the loss of constraints on

99 LC8 dimers could bind in either a paired "in-register" or a

100 DDB2 localization to cyclobutane pyrimidine dimer crosslinks to govern their repair.

101 ED patients who had any of the following: D-dimer, CTPA, scintillation ventilation perfusion lung sc

102 50.7%) when compared with the conventional D-dimer cutoff level to rule out thromboembolic disease (<

103 D-Dimer cutoff levels adjusted for renal dysfunction appea

104 imated glomerular filtration rate-adjusted D-dimer cutoff levels are applied.

105 Furthermore, adjusted D-dimer cutoff levels seem reliable in patients with acute

106 imated glomerular filtration rate-adjusted D-dimer cutoff levels.

107 Mutagenesis experiments reveal that the dimer-decamer equilibrium is delicately balanced and can

108 lo and observe that the relationship between dimer-decamer transitions and intersubunit disulfide bon

109 ndent phenotypes were unaffected in Notch1/2 dimer-deficient mice, a subset of tissues proved highly

110 resolvase dimers, except for the one special dimer-dimer interaction required for catalysis.

111 ulated energies of higher-order groupings of dimers discernible in the lattices we predict early asse

112 ampled from the transition state (TS) of the dimer dissociation reveal that the final outcome depends

113 The formation of dimers due to hydrogen bonding and dispersion forces was

114 Bivalent domain-swapped Fab dimers engineered on the basis of HC84.26.5D may also se

115 dogenous levels most of TRKA is in a monomer-dimer equilibrium and that the binding of NGF induces an

116 lusively by R interactions between resolvase dimers, except for the one special dimer-dimer interacti

117 The Greek cross (+)-orientation of pentacene dimers exhibits a selectively higher electron-transfer c

118 tals, an inversion centre, emerges in solute dimers extant in solution prior to crystallization.

119 hese species indicate that the tetramers and dimers favor less compact structures at elevated tempera

120 ponins, plasminogen activator inhibitor-1, D-dimer, fibrinogen, C-reactive protein, sST2, galectin-3,

121 rmation changes (compression) in the tubulin dimer following the hydrolysis of GTP have been suggeste

122 Central to dimer formation is a domain swap of the conserved C-term

123 Dimer formation is accelerated by H(2)O(2) and hindered

124 Asymmetric dimer formation of epidermal growth factor receptor (EGF

125 molecules is proposed to be best obtained by dimer formation, promoting supramolecular double helices

126 c macromolecule analysis to show that a HydF dimer forms a transient interaction complex with the hyd

127 y the second example of a domain-swapped Fab dimer from among >3000 Fab crystal structures determined

128 rmation of constitutional and stereoisomeric dimers from a single monomer are lacking.

129 d uvrC genes, removes cyclobutane pyrimidine dimers from the genome in a manner identical to the prok

130 hysiological conditions, FXIII-A exists as a dimer (FXIII-A2).

131 ithout a single galloyl motif (specifically, DIMER(G) and DIMER(NG)) and their precursor material, en

132 r dentin treated with e-GSE as compared with DIMER(G) and DIMER(NG); all biointerfaces remained stabl

133 Fractions consisting of DIMER(G), DIMER(NG), and their precursor, e-GSE, increas

134 D-dimer greater than 2,600 ng/mL predicted venous thromboe

135 Directly linked porphyrin dimers have attracted considerable attention because of

136 nds induce differential stabilization of RTK dimers, here, we seek to test this hypothesis for NGF an

137 trategy for using the improved light-induced dimer (iLID) system with a constructed tandem dimer of i

138 ic antibody would be unable to bind the CD73 dimer in a bivalent manner, implicating crosslinking of

139 at construct (Brpt1.5) forms an antiparallel dimer in the presence of 2-3 Zn(2+) ions.

140 cameric half-sites, and data suggest one p53 dimer in the tetramer binds to each half-site.

141 We report the use of a rhodium(II) dimer in visible light photoredox catalysis for the aero

142 The transposase forms an asymmetric dimer in which the two central domains synapse the ends

143 r, implicating crosslinking of separate CD73 dimers in its mechanism of action.

144 evidence for the spontaneous formation of OR dimers in living cells under physiological conditions is

145 hGH significantly increased formation of hGH dimers in pituitary cells.

146 t reports of SB-CS have focused on molecular dimers in solution where the environmental polarity can

147 MSA-2 exists as interconverting monomers and dimers in solution, but only dimers bind and activate ST

148 presence of islands of uncompressed (GMPCPP) dimers in the microtubule lattice.

149 stabilities of the NGF- and NT-3-bound Trk-A dimers in the plasma membrane and at neutral pH.

150 The TrkA ring splits into two TrkA dimers in the presence of ATP and releases the constrain

151 c naturally existing Bence-Jones light-chain dimers in their variable domains and remain wild-type in

152 s complemented by dimerization and expedites dimer incorporation into growth sites.

153 The dimer induced a stronger E domain I (EDI)- and EDII-targ

154 This dimer-induced aggregation mechanism may be of relevance

155 editing concludes in the 5' region, KPAF1/2 dimer induces A/U-tailing to activate translation.

156 ereby phosphorylation in one protomer of the dimer inhibits phosphorylation in the second protomer, l

157 wo res recombination sites and six resolvase dimers interact to form a synapse.

158 HSI2 and HSL1 dimers interact with RY elements at DOG1 promoter.

159 nalysis suggested that both mutations affect dimer interactions and presumably distort the DNA-bindin

160 mutated three conserved residues in the Nef dimer interface (Leu(112), Tyr(115), and Phe(121)) and d

161 These various sites and the conserved dimer interface could be exploited for the development o

162 region at the active state asymmetric kinase dimer interface do not affect the stability of ligand-in

163 ast, detergent-resistant lipids bound at the dimer interface in the leucine transporter show decrease

164 A CA inter-hexamer dimer interface mutation led to a loss of induced PIP2 c

165 Conserved loops at the CBD dimer interface straddle a conserved peripheral NBD heli

166 meric complexes on Psi RNA require an intact dimer interface within Gag.

167 dimer with two (p)ppGpp binding sites at the dimer interface.

168 outer edges, and basic side grooves near the dimer interface.

169 Of all the inter-dimer interfaces, the CB interface has the least area an

170 Crucial for stabilization of EGFR asymmetric dimer is a "latch" formed between kinase domains of the

171 The dimer is cleaved into its parent radicals when exposed t

172 ecture of the doughnut-shaped Fab HC84.26.5D dimer is completely different from that of the previousl

173 The intrinsic PRC2 dimer is formed via domain swapping involving RBBP4 and

174 The CBD dimer is oriented perpendicularly to the NBDs and its pu

175 motif, in which a self-intercalated c-di-GMP dimer is tightly bound by a network of H bonds and pai-s

176 udied extensively, the structure of a strand dimer is unknown.

177 ce in (-)ESI efficiency between monomers and dimers is expected to be broadly applicable to other bio

178 We show that growth by dimers is preferred due to overwhelming accumulation of

179 These dimers lack efficacy in a colitis mouse model, whereas t

180 tractive London dispersion forces in the pai-dimers lead to improved forecasts of sigma- vs pai-dimer

181 The mean d-dimer level was 1774 ng/mL and 6432 ng/mL d-dimer units

182 dehydrogenase (LDH) level, ferritin level, d-dimer level, neutrophil count, and neutrophil-to-lymphoc

183 te blood cell count (P = .005), and higher D-dimer levels (P = .044) were also significantly associat

184 reported fever and myalgia, and had lower D-dimer levels compared to White patients (p&0.05).

185 y embolisms and the degree of elevation of D-dimer levels does not differ between patients with COVID

186 er reaction times compared with those with D-dimer levels less than or equal to 2,000 (4.8 vs 5.6 min

187 ne low BMI and hemoglobin and high CRP and D-dimer levels may be clinically useful predictors of IRIS

188 When adjusted D-dimer levels were applied, test characteristics remained

189 irus disease 2019 (COVID-19) have elevated D-dimer levels.

190 hile phosphorylation levels are dependent on dimer lifetimes.

191 se a dynamic equilibrium between monomer <-> dimer <-> tetramer <-> hexamer, which becomes directiona

192 reatment of D with MeOH affords two isomeric dimers, MD1 and MD2, both of which incorporate a methoxy

193 ppt(v) limits of detection for proton-bound dimers measured for a series of ketones.

194 ian, 135 pg/mL) and macrophage activation (D-dimer median, 5284 ng/mL).

195 -PK at 3.5- angstrom resolution and reveal a dimer mediated by the Ku80 C terminus.

196 , with the formation of transient surfactant dimers mediated by the counterions that promote the stab

197 d by MYC:MAX dimers are repressed by MNT:MAX dimers, MNT is considered a transcriptional antagonist o

198 eanthrylene chromophores were connected into dimer model systems with the chromophores either project

199 corporates dimer and monomer photoreception, dimer/monomer cycling, abundance of native COP1 and RUP

200 We examined UVR8 dimer/monomer status, gene expression responses, amounts

201 The dimer N levels include local and charge transfer exciton

202 to monomers (SARS-CoV-2) but also to cyclic dimers (Newcastle disease, Lyme disease), trimers (influ

203 le galloyl motif (specifically, DIMER(G) and DIMER(NG)) and their precursor material, enriched grape

204 Fractions consisting of DIMER(G), DIMER(NG), and their precursor, e-GSE, increased the mod

205 ted with e-GSE as compared with DIMER(G) and DIMER(NG); all biointerfaces remained stable after 12 mo

206 gonal closed-packed Te sublattices and Si-Si dimers occupying octahedral intercalation sites.

207 The commercially available dimer of cinchona derivatives (DHQ)(2)PYR was used as a

208 intain normal levels of cystine-the oxidized dimer of cysteine-in melanosomes, and to produce cystein

209 ASO binding also induces the formation of a dimer of dimers of PC4, which is stabilized by base pair

210 The tetramer is a dimer of dimers, wherein the membrane-interacting BAR su

211 imer (iLID) system with a constructed tandem dimer of its binding partner nano (tdnano) to build ligh

212 homologous regions of the ASOs bound by each dimer of PC4.

213 G(asc) values for 36 TM complexes, including dimers of 10 glycophorin A mutants.

214 , mediated through coordinated activation by dimers of Arabidopsis (Arabidopsis thaliana) ARF-GEF GNO

215 action-based chemosensors using porphyrinoid dimers of nonplanar subunits with biased reactivity.

216 ing also induces the formation of a dimer of dimers of PC4, which is stabilized by base pairing betwe

217 Chirality recognition in dimers of tetrahydro-2-furoic acid (THFA) was studied in

218 incorporated cassettes of two F30-scaffolded dimers of the Broccoli aptamer into a SINV cDNA clone us

219 inct dinitrogen species in the two alphabeta dimers of the protein.

220 3 tridomain fragment of VWF, plasmin-cleaved dimers of VWF, multimeric recombinant VWF, and normal VW

221 al and structural analyses indicate that the dimer-of-dimers configuration represents an inactive sta

222 tural dynamic steady states from monomers to dimers, oligomers of dimers, and randomized polymer stru

223 the lifetime of the putative reactive NO(2) dimer on the surface of pure water droplets is too small

224 Native LGR4 and LGR5 existed as dimers on the cell surface, and LGR5 interacted with bot

225 due to overwhelming accumulation of adsorbed dimers on the crystal surface, where it is complemented

226 D-dimers on the day of CT pulmonary angiography had a pred

227 t inner-sphere complexation of Tc(IV)-Tc(IV) dimers onto a Fe oxide like hematite at pH 6.00 +/- 0.07

228 e suggested that the receptor may exist as a dimer or an oligomer.

229 the capsomere and not the previously touted dimer or trimer interfaces as the key contributor to cap

230 nding CRD2 subdomain retained the monomer-to-dimer ratio of the unliganded wild-type TNFR1 but exhibi

231 eted response that involves dynamic receptor dimer rearrangements and that is kinetically embedded be

232 P) tend to narcissistically self-sort in the dimer regime, each enantiomer showing a strong preferenc

233 sites are placed at mid cell for subsequent dimer resolution.

234 Cryo-EM of the NTD dimer revealed a structural similarity to the scaffold d

235 ed in models, but instead interacts with the dimer's surface.

236 ve site that spans the interface between two dimers, sandwiching the cA(4) substrate.

237 This work shows that Ponatinib and BRAF dimer selective inhibitors will be useful in treating BR

238 mer is occupied, comprising a novel class of dimer selective inhibitors.

239 dergo self-assembly either as a tail-to-tail dimer, showing monomer-dimer sigmoidal transitions, or a

240 her as a tail-to-tail dimer, showing monomer-dimer sigmoidal transitions, or as a head-to-tail noncen

241 ounds, including one proposed to disrupt the dimer, slow the rate of substrate processing by ~35 %.

242 mer, as well as exchange of both monomer and dimer species with high-molecular-weight oligomers.

243 sage, by facilitating removal of the H2A-H2B dimer, stabilizing intermediate subnucleosomal states an

244 mma) is controlled by the latency-conferring dimer state, the activation of the monomeric AtLEGbeta i

245 In mice, the dimers stimulated 3-fold-higher levels of virus-specific

246 rs are the most thermodynamically stable RAF dimers, suggesting that RAF heterodimers, and not homodi

247 signed transcription activator-like effector dimer (TALED) proteins.

248 of 1 resulted instead in a dinuclear helical dimer, [((tBu)pyrr(2)py)Fe](2) (3), via bridging of the

249 the presence of multiple conformers for the dimer, tetramer, and hexamer that precede the Cu(II)-ind

250 use two clusters to realize a larger cluster dimer that behaves as a single electronic unit, possessi

251 thic hydrogen-bonded antiparallel beta-sheet dimer that binds chloride anions.

252 The protein LpThi5 is a dimer that binds pyridoxal-5'-phosphate (PLP), apparentl

253 while two C-terminal domains form a separate dimer that contacts only one transposon end.

254 verall structure of NfoR-Cu(II) complex is a dimer that covalently binds with FMN and Cu(II)-binding

255 ional coupling of two SERCA2a protomers in a dimer that reduces the energy barrier of rate-limiting s

256 For adjacent dimers that are oriented and immobilized in an inert hos

257 e find that SCF-FBXL17 disrupts aberrant BTB dimers that fail to stabilize an intermolecular beta-she

258 um was tentatively identified as sulfonimide dimers that were either a minor component of the AFFF or

259 ) complex (LFC) consists of the inactive Rag dimer, the pentameric scaffold Ragulator, and the FLCN:F

260 In the dimer, the protomers faced each other through the F and

261 the Gbeta and Ggamma proteins form obligate dimers, the phenotypes of plants lacking the sole Gbeta

262 that 5-benzyloxygramine stabilizes the N-NTD dimers through simultaneous hydrophobic interactions wit

263 ed and suggested that HSI2 and HSL1 can form dimers to directly regulate DOG1.

264 er a complete protein unfolding, from native dimers to Gaussian chains, or a partial unfolding with o

265 nd MS(2) analysis revealed the presence from dimers to pentamers of native procyanidins.

266 ssembly path from hepatitis B capsid protein dimers to the 120-dimer capsid.

267 D) conformation to enhance the exposure of E dimers to the immune system.

268 esults demonstrate a pH-dependent monomer-to-dimer transition, clear evidence of membrane association

269 , N+8, N+10, N+12, and N+14 assemble to form dimers, trimers, and hexamers in solution-phase studies.

270 mbrane-bound proteins exists as non-covalent dimers, trimers, and higher-order oligomers.

271 that lead in particular to the formation of dimers, trimers, and similar clusters in a material.

272 -dimer level was 1774 ng/mL and 6432 ng/mL d-dimer units in CT pulmonary angiography-negative and CT

273 icity (71%) for PE diagnosis at 1394 ng/mL d-dimer units.

274 ted C-reactive protein level, and a rising d-dimer value over time.

275 disease 2019 include obesity, an elevated d-dimer value, elevated C-reactive protein level, and a ri

276 Those with D-dimer values greater than 2,000 were more likely to have

277 We find that the cooperativity between Cbf1p dimers varies sinusoidally with a period of 10.65 bp and

278 macrocyclic derivatives: (1) a figure-eight dimer via alkyne metathesis (also gram scale) and (2) tw

279 erol 14alpha-demethylase (AcCYP51)] formed a dimer via an N-termini swap, whereas drug-bound AcCYP51

280 Elevated admission D-dimer and peak D-dimer were associated with venous thromboembolism develo

281 el and anti-parallel variants of Abeta(1-40) dimers were designed and synthesized, and their pathogen

282 Thymine dimers were found at a potential of about 1.1 V in ammon

283 D-dimers were markedly higher in patients with deep venous

284 Two diastereomeric crystalline steroid dimers were obtained by acid-catalyzed double acetalizat

285 tetrahydroisoquinoline-based benzodiazepine dimers were synthesized and tested for in vitro cytotoxi

286 The tetramer is a dimer of dimers, wherein the membrane-interacting BAR surfaces ar

287 direct evidence suggests that ORs might form dimers, which could be endowed with a distinct pharmacol

288 4 interaction interface with ATP-bound HSP70 dimers, which leaves them intact and thereby eliminates

289 y a significant free energy barrier from the dimer with a native binding interface.

290 ex with the NAD(+) cofactor showed a protein dimer with a Rossman fold.

291 of the two SEC7 domains of the GNOM ARF-GEF dimer with its ARF1 substrate reduced the efficiency of

292 A linked BchL dimer with one defective ATP-binding site does not suppo

293 nct from HPRT in that XPRT forms a symmetric dimer with two (p)ppGpp binding sites at the dimer inter

294 y study on the stepwise hydration of the Gly dimer with up to three water molecules.

295 ical 24-monomer complex composed of 12 HSP27 dimers with a phosphorylation pocket flanked by serine r

296 actions consisting exclusively of B-type PAC dimers with or without a single galloyl motif (specifica

297 Most restriction enzymes act as dimers with two catalytic sites, and cleave the two stra

298 ibits discrete cellular selectivity for BRAF dimers, with enhanced inhibition of the second protomer

299 conformation and nucleotide state of tubulin dimers within the microtubule lattice.

300 complex from docking poses containing a homo-dimer without prior knowledge of the number (n) of monom