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1 tion), vancomycin was mainly monomeric (<20% dimerized).
2 pha2, and alpha4 C-terminal globular regions dimerize.
3 stricting how the N-terminal RING domain can dimerize.
4 nactive conformations, and R975W MV fails to dimerize.
5 e hydrophobicities and different tendency to dimerize.
6 laden ECAM is shed from the membrane and may dimerize.
7 8del is the result of an impaired ability to dimerize.
8 ntly than a mix of the two enzymes unable to dimerize.
9 t mechanism whereby these family C receptors dimerize.
10 hat, A52-M65E was impaired in its ability to dimerize.
11 nce cross-correlation shows that it fails to dimerize.
12 de (2b, E1/2 = 0.98 V) show less tendency to dimerize.
13 its effect on the ability of RGII pectin to dimerize.
14 ects, but only p.R33Q convincingly failed to dimerize.
15 embrane, reducing the drive of QUAD opsin to dimerize.
16 ic and activates MAPK only when artificially dimerized.
17 accumulate in EVs over time and amyloid-beta dimerizes.
18 ltiple consequences of activation until Plk4 dimerizes.
19 and biochemical data suggest that RSV M also dimerizes.
20 in vivo cross-linking study shows that AmpR dimerizes.
21 NA damage, colocalization increases and RecF dimerizes.
22 on-promoting factor (HPFSa) is sufficient to dimerize 2.5-MDa 70S ribosomes into a translationally in
25 Furthermore, hybrid synthekine ligands that dimerized a JAK/STAT cytokine receptor with a receptor t
28 We describe Homo-PROTACs as an approach to dimerize an E3 ligase to trigger its suicide-type chemic
29 are synthesized as inactive precursors that dimerize and are then cleaved to generate both the bioac
31 However, the S. aureus BirA was reported to dimerize and bind DNA in the absence of biotin or biotin
34 laced on the corners of a square lattice can dimerize and form singlets, which then can be transforme
35 which copurifies with Microprocessor and can dimerize and interact with other proteins that can dimer
36 d with its reduced ability to non-covalently dimerize and its inability to bind and recruit TbetaRI,
37 ike receptors (TLRs), such as TLR2 and TLR4, dimerize and move laterally across the plasma membrane t
38 FoxP1, FoxP2, and FoxP4 are coexpressed, can dimerize and multimerize with each other and differentia
39 stal structures, we learn that hydroxyanions dimerize and oligomerize by overcoming long-range electr
40 that the mutant increases the propensity to dimerize and perturbs the secondary structure compositio
41 of the short lifetime of CO2(*-), which can dimerize and react with proton donors and even mild oxid
42 ters to mitochondrial NFU1, which appears to dimerize and reductively mediate the formation of a brid
43 We also designed Bcl-xL mutants which cannot dimerize and show that these mutants reduced mitochondri
45 e domain also interferes with its ability to dimerize and subsequently bind CrkII, suggesting that th
46 ariant had a reduced melting temperature but dimerized and complemented growth of a temperature-sensi
47 domain in Sli15 that is essential even when dimerized and is required to target kinetochore substrat
48 he secretable LGI1(S473L) protein abnormally dimerized and was selectively defective in binding to on
50 ..O) and two nonconventional (OH...pai) HBs, dimerizes and anchors the molecule in the unit cell.
51 rA/B systems consist of ParA, an ATPase that dimerizes and binds DNA upon ATP binding, and ParB, a pr
52 for the phosphorylation of STAT3, which then dimerizes and translocates to the nucleus to form DNA-bi
53 We show that UapA oligomerizes (at least dimerizes) and that oligomerization persists upon UapA e
55 paramyxovirus M proteins have been shown to dimerize, and biochemical data suggest that RSV M also d
56 cosylated, catalytically inactive, unable to dimerize, and complexed intracellularly with the endopla
57 ic mutant of mt-tRNA(Leu), which is known to dimerize, and find that the misfolded dimeric form activ
58 dov splitting when the yellow FP Venus(A206) dimerizes, and a novel approach combining photon antibun
60 us is applied to trigger the scission of the dimerized anthracene, which reduces the modulus and glas
61 duct (Phi = 0.06) is a [2]rotaxane, with the dimerized anthracenes assuming a head-to-tail geometry,
63 rising a single Aux/IAA repressing a pair of dimerized ARFs-sufficient for auxin-induced transcriptio
72 TRIM coiled-coil and show that TRIM proteins dimerize by forming interdigitating antiparallel helical
75 onal, dome-shaped structures with Fab pairs, dimerized by hinge domains, bound to surface antigens th
77 ructure of a protein not previously known to dimerize, by predicting and validating the transmembrane
78 oid carrier protein, COCP, which consists of dimerized C-domain(s) of OCP and can combine with the is
80 Thus, A46 uses helices alpha4 and alpha6 to dimerize, compared with the alpha1-alpha6 face used by A
83 rane domains as even when NBDs are kept at a dimerized configuration, Po is reduced by approximately
85 that the EF-SAM domain partially unfolds and dimerizes cooperatively with respect to Ca(2+) concentra
90 we reconstituted the system by artificially dimerizing EB1 to kinesin, growing microtubules from imm
92 isolvated monomer 4&3THF in THF solution and dimerizes endothermically to form (4&THF)2 with a strong
93 hropoietin (EPO) and its receptor (EpoR), to dimerize EpoR ectodomains in non-native architectures.
94 ubstituents, these radicals can irreversibly dimerize, exist as monomers in solution but dimerize in
95 saccharide is the shortest length capable of dimerizing FGF1 and on longer heparin chains FGF1 binds
97 f AP20187, a cell-permeable molecule used to dimerize FK506-binding protein (FKBP) fusion proteins an
98 ites separated by a spacer sequence, and the dimerized FokI nucleases at the C terminal then cleave D
99 growth factor to the extracellular domain it dimerizes, followed by autophosphorylation of tyrosine r
104 ated with upregulation of both monomeric and dimerized forms of protein kinase G and of the cGMP hydr
105 unit: paramagnetic {Fe(NO)2}(9), diamagnetic dimerized forms of {Fe(NO)2}(9) and diamagnetic {Fe(NO)2
106 Zr12-SBU can be viewed as an inorganic node dimerized from two commonly observed Zr6 clusters via si
107 S2 anchor for genome targeting with Fkbp/Frb dimerizing fusion proteins to allow chemical-induced pro
109 ificity suggests that aptamers may encounter dimerized GagPol in the cytosol during viral assembly.
110 KF1 with the optimization of a split FKF1/GI dimerized Gal4-VP16 transcriptional system, we identifie
111 hod to probe the solution phase structure of dimerized Gramicidin A (GA) inserted into lipid vesicle
112 a quantum magnet with antiferromagnetic and dimerized ground states confirm the form, proving a cont
115 ed-coil arms are consistently bridged by the dimerized hooks while the Mre11/Rad50 ring opens by disc
117 However, unlike LacI/GalR proteins, which dimerize in a parallel, side-to-side manner, XylR PBP di
120 drophobic surface in crystallo, A49 does not dimerize in solution or in cells, and we propose that th
122 has been previously proposed to specifically dimerize in the absence of a disorder-to-order transitio
123 itional understanding that steroid receptors dimerize in the absence of DNA, it is fully consistent w
125 Thus, it is often hypothesized that RNAs dimerize in the cytoplasm and the RNA-Gag complex is tra
126 ting factor (hpf), which causes ribosomes to dimerize in the dark and may contribute to decreased tra
127 Although it is well known that proteins may dimerize in the ER in principle, our data show that the
130 dimerize, exist as monomers in solution but dimerize in the solid state, or can even remain monomeri
131 tides downstream from the 5' splice site can dimerize in vitro through an intermolecular G-quartet st
134 e further show that the kinase domain of PKD dimerizes in a concentration-dependent manner and autoph
135 onomeric in the absence of phenylalanine and dimerizes in its presence, similar to the regulatory dom
136 Previously, we showed that active K-Ras4B dimerizes in silico and in vitro through two major inter
139 Here we show that unphosphorylated IRAK4 dimerizes in solution with a KD of 2.5 muM and that Mydd
142 ansfer assay, we show that functional NRT1.1 dimerizes in the cell membrane and that the phosphomimet
144 e isomerization process, showing that CfPutA dimerizes in the presence of a proline analog and NAD(+)
145 (-) , which features discrete Al-O bonds and dimerizes in the solid state via weak O...K interactions
147 y as a pigment-free monomer in cells but can dimerize, in which case its CAB domain creates a functio
148 mes form distinctively shaped dimers, with a dimerizing insertion spatially separating independently
150 ccur as approximately 500-kDa complexes that dimerize into active approximately 900-kDa complexes upo
154 e(III)(SH)4](-) (5) in THF/DMF spontaneously dimerized into the first structurally characterized Fe(I
155 ation studies then revealed how ACAP1, which dimerizes into a symmetrical structure in solution, is r
156 ecular dynamic simulations demonstrated that dimerized intracellular proteins cooperate in sensing HM
157 V948R) that perturbs the ability of EGFR to dimerize intracellularly, we showed that a modest drug-i
158 we show that the propensity of vitamin A to dimerize is responsible for triggering the formation of
160 he N-terminal domain interface by which VP40 dimerizes is conserved between Ebola virus and SUDV, the
164 We engineered a minimal CPC comprised of the dimerized last third of the kinase-activating Sli15/INCE
166 principal nucleic acid-binding domain with a dimerizing leucine zipper domain leads to the assembly o
167 timulation was achieved in IFPs containing a dimerizing motif and a predicted tumor-T-cell distance t
168 SAC stimulates SAC signaling by artificially dimerizing Mps1 kinase domain and a cytosolic KNL1 phosp
171 inellid alkaloids, when attempts to directly dimerize Nature's presumed monomeric precursors in a put
172 glycoluril-based dimers, these clips neither dimerize nor accept any organic guests, due to their sma
175 ike TLRs located on the plasma membrane that dimerize on the membrane after ligand binding to their e
177 ization (CID) systems, in which two proteins dimerize only in the presence of a small molecule ligand
181 g manner, and anisotropic particles, such as dimerized or rod-shaped particles, can travel linearly w
182 uring ADAM8 maturation, the inactive proform dimerizes or multimerizes and autocatalytically removes
183 are best suited for the study of monomeric, dimerizing, or dimeric proteins but have limitations in
184 d allows two structure-free N termini of the dimerized ORF57 to work coordinately for host factor int
185 specifically attached in the junction of the dimerized origami to act as a Raman reporter molecule.
186 thout CaM bound are similar, consisting of a dimerized oxidase domain flanked by two separated reduct
187 uring exposure to certain stresses, bacteria dimerize pairs of 70S ribosomes into translationally sil
188 e document the preparation and properties of dimerized pentaphosphate-bridged deoxynucleotides (dicap
191 removal of both cholesterol anchors from the dimerized prisms via two displacement strands cleanly re
192 ermine the solid-state structure of the 100% dimerized product and three intermediate structures, eve
193 la Engrailed homeodomain (ENH), allowing the dimerized protein complex to bind to two double-stranded
194 thermally equilibrated all-trans-tetraureas dimerize quantitatively, encapsulating one Me4P(+) catio
195 report on magnetization measurements on the dimerized quantum magnet SrCu2(BO3)2 at cryogenic temper
196 energy between cisternae and mitochondria by dimerizing rapamycin-binding domain and FK506-binding pr
197 ble organometallic transient and is known to dimerize rapidly with the formation of a MnMn single bon
198 Agonistic antibodies are powerful tools to dimerize receptors in the absence of ligand binding, but
199 ng, EGFR undergoes conformational changes to dimerize, resulting in kinase activation and autophospho
200 structures, formed by 2-domain monomers that dimerize, revealed few contiguous regions of similar exp
202 de hibernation-promoting factor (HPF), which dimerizes ribosomes and prevents translation of mRNA.
203 tration calorimetry that the ETS member PU.1 dimerizes sequentially at a single sequence-specific DNA
204 ontrast, the more distantly related ER-alpha dimerizes so strongly that energetics can only be measur
207 reover, these MBP2 and MBP3 oligomers can be dimerized specifically, such that generation of MPB4 and
208 ome near the central polypurine tract (cPPT) dimerizes spontaneously under high ionic strength in the
209 se compounds also significantly decrease the dimerized STAT3 levels, the binding of nuclear STAT3 to
210 mutant of STAT3 that forms a constitutively dimerized STAT3, rescues cells from the effects of S3I-1
211 Here we report that a quantum entangled dimerized state or valence bond crystal (VBC) phase of L
214 were immobilized on rectangular DNA origami dimerized structures to create nanoantennas containing m
215 ze and interact with other proteins that can dimerize, suggesting a model in which one Microprocessor
218 _2091 was predicted to encode an enzyme that dimerized the monomeric naphtho-gamma-pyrones in V. vire
219 NA-bound precomplex after its nuclear export dimerizes the motor and activates processive RNA transpo
220 ave generated potent MV fusion inhibitors by dimerizing the F-derived peptides and conjugating them t
224 from the known tendency of GFP molecules to dimerize through localized hydrophobic patches and from
227 0021, prepared by solid-phase synthesis, was dimerized through a naturally-occurring, carboxy-termina
228 for gingipains, the isolated Kgp pro-domain dimerized through an interface, which partially overlapp
229 enosine triphosphatase (ATPase) active sites dimerizes through association between the Rad50 ATPase c
230 ates in the blood as a globular protein that dimerizes through disulfide bridges generated by cystein
240 the extracellular protein MD-2 bound to and dimerized TLR4 in order to promote this endocytic event.
242 ment in solution whereby the {HPO3} moieties dimerize to form a weakly interacting (O3PHHPO3) moiety.
246 that ABC half-transporters have at least to dimerize to generate a functional unit, functional equiv
250 II) from (pyridine-pyrrolyl)Ni-methyl, which dimerizes to afford a bimetallic Ni(III) intermediate.
254 complex that contains no hydride ligand and dimerizes to form an unsupported Co-Co bond in the solid
255 osition whereby UBN1 associates with DNA and dimerizes to mediate formation of an (H3.3/H4)(2) hetero
256 analyses showed that the WR domain of TWIST dimerizes to mediate tetramer formation, which is functi
257 first deaminate viral DNA as monomers before dimerizing to form multiple enzymatically deficient road
259 s are a large class of soluble proteins that dimerize transmembrane receptors into precise signaling
260 inked coiled coils, so SpyTag-fusions can be dimerized, trimerized, tetramerized, pentamerized, hexam
261 specific positions that can be subsequently dimerized upon light irradiation, extending the use of M
262 efined the minimal length of PAM required to dimerize using a series of peptides with additional PAM
267 o terminal nitrenes [(i) Pr2 NN]Cu]=NAr that dimerize via formation of a C-C bond at the arylnitrene
269 icle membranes have previously been shown to dimerize via transmembrane (TM) domain interactions.
271 Our bacterially expressed KIF1A construct, dimerized via a kinesin-1 coiled-coil, exhibits fast vel
272 MD) of EphA2 embedded into the lipid bicelle dimerized via the heptad repeat motif L(535)X3G(539)X2A(
273 ur findings suggest the following model: Gag dimerizes via the CA-CTD dimer interface just before or
274 e x-ray scattering analysis shows that RIFMO dimerizes via the FAD-binding domain to form a bell-shap
276 binding was due to the inability of VEK30 to dimerize, we defined the minimal length of PAM required
277 the extracellular domains reveal that Lphn3 dimerizes when bound to FLRT2:Unc5, resulting in a stoic
279 entration of 5 mg.mL(-1) all glycopeptide is dimerized whilst at 19 microg.mL(-1) (a clinical target
282 n of GGA1t is attributed to its abilities to dimerize with its wide type counterpart and to inhibit c
284 ctivated receptor-4 (PAR4) has been shown to dimerize with the purinergic receptor P2Y12 to coordinat
285 uce truncated, inactive proteins that do not dimerize with WT DNMT3A, strongly supporting the haploin
288 The nucleotide-binding domains of SUR1 are dimerized with Mg(2+)-ATP in the degenerate site and Mg(
289 that all three TBX18 altered proteins still dimerized with the wild-type protein but had prolonged p
297 -associated mutant G605R Gars (G526 in GARS) dimerizes with the remaining wild-type protein in animal
298 activated protein kinase (MAPK) signaling by dimerizing with and activating WT C-Raf proto-oncogene,
299 e data demonstrate that wild-type proinsulin dimerizes within the ER but accumulates at a poorly reco