ライフサイエンスコーパス: dimethylamino

1 peridyl) and (1-NMe2-2-BH2-C6H4)2 (4; NMe2 = dimethylamino).

2 ,5-tetrakis(amino)benzene compounds, bearing dimethylamino (1), piperidin-1-yl (3), or morpholin-1-yl

3 available 2-(dicyclohexylphosphino)-2'-(N,N-dimethylamino)-1,1'-biphenyl that has been useful in C-N

4 ew ligand, 2-(dicyclohexylphosphino)-4'-(N,N-dimethylamino)-1,1'-biphenyl, was synthesized.

5 2,4,6-Tris(dimethylamino)-1,3,5-triazine was prepared to complete t

6 e-containing inhibitors [S-(R*,R*)]-N-[4-[2-(dimethylamino)-1-(1H-imidazole-1-yl)propyl]-phenyl]2-ben

7 ethylaminomethyl)phenols with (2 E)-3-( N, N-dimethylamino)-1-(2-hydroxyphenyl)prop-2-en-1-ones and t

8 y with the discovery of the lead compound 3-(dimethylamino)-1-(4-hexylphenyl)propan-1-one).

9 enhancement of the dansyl fluorescence of 5-(dimethylamino)-1-(naphthalenesulfonyl)glutamylglycylargi

10 of type I IDI from crystals soaked with (N,N-dimethylamino)-1-ethyl diphosphate (NIPP), a potent tran

11 of a fluorogenic sulfonamide derivative, 5-(dimethylamino)-1-naphthalenesulfonamide (dansylamide, DN

12 = 23.680(5) A; (2) (DMAPA)PbBr4 (DMAPA = 3-(dimethylamino)-1-propylamine), which crystallizes in P21

13 )- or 2-(1'-hydroxy-4'-methylphen-2'-yl)-4,6-dimethylamino-1,3,5-triazine with ICl provides species d

14 Derivatives of isomeric 2-(hydroxytolyl)-4,6-dimethylamino-1,3,5-triazines have been synthesized in h

15 ased on the solvatochromic fluorophore 4-N,N-dimethylamino-1,8-naphthalimide (4-DMN) for application

16 ive displacement of the fluorescent probes 5-dimethylamino-1-naphthalenesulfonamide and dansyl-l-prol

17 (R)-4-(3-Dimethylamino-1-phenylsulfanylmethyl-propylamino)-N-{4-[

18 Forosamine (4-dimethylamino)-2,3,4,6-tetradeoxy-beta-D-threo-hexopyran

19 new environment-sensitive fluorophore, 6-N,N-dimethylamino-2,3-naphthalimide (6DMN).

20 ,N-dimethylaminophthalimidoalanine and 6-N,N-dimethylamino-2,3-naphthalimidoalanine amino acids.

21 new series of novel P450 substrates using 6-dimethylamino-2-naphthaldehyde (6-DMANA), which has a gr

22 D-Desosamine, or 3-(dimethylamino)-3,4,6-trideoxyglucose, is an unusual suga

23 D-desosamine (1) is a 3-(N,N-dimethylamino)-3,4,6-trideoxyhexose found in a number of

24 Desosamine is a 3-(dimethylamino)-3,4,6-trideoxyhexose found, for example,

25 A structurally similar analog, 1-(2-dimethylamino-3-methyl-butyryl)-azetidine-2-carbonitrile

26 ubstitution from azido (3a) to amino (3b) to dimethylamino (3c) groups.

27 ompared to those of DMABN and 2-cyano-7-(N,N-dimethylamino)-4,5,9,10-tetrahydropyrene, and we show th

28 caspase-based HTS assay, 2-amino-3-cyano-7-(dimethylamino)-4-(3-methoxy-4,5-methylenedioxyphenyl)-4

29 no)-4H-chrom ene (1c) and 2-amino-3-cyano-7-(dimethylamino)-4-(5-methyl-3-pyridyl)-4H-chromene (4e),

30 ctivity was inhibited by the CK2 inhibitor 2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole DMAT w

31 Inhibition of CK2 kinase by 2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole result

32 s (4,5,6,7-tetrabromo-1H-benzotriazole and 2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole) and g

33 (i.e. 4,5,6,7-tetrabromo-1H-benzimidazole, 2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole, tetra

34 o-4-(3-bromo-4,5-dimethoxyphenyl)-3-cyano-7-(dimethylamino)-4H-chrom ene (1c) and 2-amino-3-cyano-7-(

35 unreacted starting material or with added 3-(dimethylamino)-5,5-dimethyl-2-cyclohexen-1-one.

36 generated by covalently attaching a single 2-dimethylamino-6-acyl-naphthalene group to the N-terminal

37 inhibitors indolopyridone-1 (INDOPY-1) and 4-dimethylamino-6-vinylpyrimidine-1 (DAVP-1).

38 ne (7,8-DHF) and its synthetic derivative 4'-dimethylamino-7,8- dihydroxyflavone (4'-DMA-7,8-DHF) to

39 9-Dimethylaminobenzo[ g]indoles 3-6 and 1-dimethylamino-8-(pyrrolyl-1)naphthalene 7 were examined

40 N-(6-oxo-5,6-dihydrophenanthridin-2-yl)(N,N-dimethylamino)acetamide hydrochloride (PJ34), using virt

41 nium diiodide), and acridine orange (3,6-bis(dimethylamino)acridinium chloride), as well as 140 copie

42 ectivity in comparison to ARs; related 6-N,N-dimethylamino analogue 30 was 5HT2R-selective.

43 placing desosamine with varied synthetic N,N-dimethylamino anchoring groups.

44 cell growth and tubulin polymerization, the dimethylamino and bromo cis-stilbenes were the most pote

45 ologically and pharmaceutically important o-(dimethylamino)aryl ketones, acridones, acridinium salts,

46 In contrast, the dimethylamino-aza-BODIPY derivative, 3c, showed negligib

47 the quencher nucleosides possessing 6-{4-[(4-dimethylamino)azo]phenyl}pyrrolocytosine (DABCYLpC) and

48 ystals of an azo compound, 3',4'-dimethyl-4-(dimethylamino)azobenzene that can be used as a crystalli

49 The method is based on detection of the 4-(dimethylamino)azobenzene-4'-sulfonyl derivative of l-met

50 gy transfer, using lipid II analogues with a dimethylamino-azobenzenesulfonyl quencher in the lipid c

51 or systems were camphorquinone (CQ)/ethyl 4-(dimethylamino)benzoate (EDMAB) with or without [3-(3, 4-

52 novel self-cure system mediated by ethyl 4-(dimethylamino)-benzoate (4E) and hydroxyapatite (HAp).

53 D(4), D(6), and D(10)) deuterium enriched 4-(dimethylamino)benzoic acid (DMABA) N-hydroxysuccinimide

54 4-(Dimethylamino)benzoic acid, 1-naphthylacetic acid, and 9

55 The selected model aromatic amine, 4-(dimethylamino)benzonitrile (DMABN), was subjected to las

56 gue of the widely studied chromophore 4-(N,N-dimethylamino)benzonitrile (DMABN).

57 en were identified: leucomalachite green, 4-(dimethylamino) benzophenone, 4-dimethylaminophenol, benz

58 l)-N-hydroxybenzamide (3c) and (E)-4-((2-(4-(dimethylamino)benzoyl)-2-methylhydrazono)methyl)-N-hydro

59 ition, the effect of compounds (E)-4-((2-(4-(dimethylamino)benzoyl)hydrazono)methyl)-N-hydroxybenzami

60 Notably, the 3,5-bis(N,N-dimethylamino)benzyl cation is predicted to have a tripl

61 nylcarbamoyl)acrylic acid (3) and (E)-N'-(4-(dimethylamino)benzylidene) diazenecarboximidhydrazide (5

62 The antiangiogenic drugs included (Z)-3-[4-(dimethylamino)benzylidenyl]indolin-2-one (a platelet-der

63 The new p-dimethylamino biphenyl ligand bears electronic similarit

64 ve probed the structures of the isomeric N,N-dimethylamino biphenyl ligands by X-ray crystallographic

65 ene)Cl2 with 2-dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl as the ligand, both electron-rich

66 utational study investigating substituted 2-(dimethylamino)biphenyl-2'-carboxaldehydes as substrates

67 izes gas-phase ion/molecule reactions of tri(dimethylamino)borane (TDMAB), which rapidly derivatizes

68 resent study, ion-molecule reactions of tris(dimethylamino)borane followed by collisionally activated

69 eries of mono- or bis(boryl) alkynes bis{bis(dimethylamino)boryl}ethyne, 1-phenyl-2-bis(dimethylamino

70 mation of a sterically unprotected terminal (dimethylamino)borylene complex that has a short metal-bo

71 mino)borylethyne, and 1-trimethylsilyl-2-bis(dimethylamino)borylethyne led to the isolation of hither

72 s(dimethylamino)boryl}ethyne, 1-phenyl-2-bis(dimethylamino)borylethyne, and 1-trimethylsilyl-2-bis(di

73 series of novel heterocyclic analogues of 3-(dimethylamino)butyl dimethylcarbamate (DMABC, 4).

74 7,7'-Bis(((dimethylamino)carbonyl)oxy)-8,8'-biquinolyl (5) was prep

75 tetramethyl-1,2-ethylenediamine with 3,6-bis(dimethylamino) chalcogenoxanthones to give S- and Se-con

76 n allene moiety and substituted with methyl, dimethylamino, cyano, and vinyl substituents were examin

77 The 3,4-dichloro-N-(1-(dimethylamino)cyclohexyl)methyl benzamide scaffold was s

78 For the first time, 10-dimethylamino derivatives of benzo[h]quinoline 6 and ben

79 -methyl-N-4-carboxyphenylamino)phenyl]1-(N,N-dimethylamino) diazen-1-ium-1,2-diolate (PABA/NO) result

80 -[4-(N-methylamino)benzoyloxy]phenyl} 1-(N,N-dimethylamino)diazen-1-ium-1,2- diolate (PABA/NO) were s

81 An electron enriched 2,4-(dimethylamino)diketiminato backbone is described, which

82 We show that N,N-(dimethylamino)dimethylchlorosilane (DMAS-Cl) reacts at t

83 tsi) (7a), Ga(Me(2)Ntsi) (7b); Me(2)Ntsi = [(dimethylamino)dimethylsilyl]bis(trimethylsilyl)methyl) m

84 r chloro (CHQ) or exchanging the hydroxy for dimethylamino (DMAQ and DMAQ-Cl) or sulfhydryl (TQ) sign

85 relies on the derivatization reaction of 2-(dimethylamino)ethanethiol (DMAET), 2-(diethylamino)ethan

86 2-(Diethylamino)ethanethiol (DEAET) and 2-(dimethylamino)ethanethiol (DMAET), the thiol-containing

87 ectron-rich alkenes, exemplified by tetrakis(dimethylamino)ethene, TDAE, and on additional driving fo

88 opolymer poly(ethylene glycol)-block-poly(2-(dimethylamino) ethyl methacrylate) (OD) readily encapsul

89 yl)triethylammonium bromide (QX-314), and 2-(dimethylamino)ethyl 4-(butylamino)benzoate (tetracaine),

90 proportionation of CuBr/Me6TREN (TREN = tris(dimethylamino)ethyl amine to Cu(0) powder and CuBr2 in w

91 agarose and a copolymer of acrylamide and 2-(dimethylamino)ethyl methacrylate (DMAEM) cross-linked wi

92 er brushes, consisting of dual-responsive 2-(dimethylamino)ethyl methacrylate (DMAEMA) and light-sens

93 linker, and 1-allylpiperazine (1-ALPP) or 2-(dimethylamino)ethyl methacrylate (DMAEMA), in combinatio

94 olymers containing the same cationic poly(2-(dimethylamino)ethyl methacrylate) (D) block but placed i

95 from solution using poly(butadiene-block-2-(dimethylamino)ethyl methacrylate) (PB-b-PDMAEMA) diblock

96 polymer micelles comprising cationic poly(2-(dimethylamino)ethyl methacrylate) (PDMA) coronas and hyd

97 PMMA), poly(n-butyl acrylate) (PBMA), poly(2-dimethylamino)ethyl methacrylate) (PDMAEMA) and poly(n-b

98 lamide) (PNIPAM) and pH responsive poly(N,N-(dimethylamino)ethyl methacrylate) (PDMAEMA) and their co

99 polyzwitterion brushes derived from poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) in water vap

100 Poly(isoprene-block-styrene-block-(N,N-dimethylamino)ethyl methacrylate) is synthesized and use

101 amphiphilic block polymer variants, poly(2-(dimethylamino)ethyl methacrylate)-block-poly(n-butyl met

102 (DB) and poly(ethylene glycol)-block-poly(2-(dimethylamino)ethyl methacrylate)-block-poly(n-butyl met

103 [2-(dimethylamino)ethyl methacrylate] (DMAEMA) was homopolym

104 Cationic poly[2-(dimethylamino)ethyl methacrylate] and anionic poly(acryl

105 hloro-2-methoxyacridin-9-yl)amino)-2-((4-(2-(dimethylamino)ethyl) piperazin-1-yl) methyl) phenol (com

106 enyl]pyrimidine (1a) and amide 4,6-bis(4[(2-(dimethylamino)ethyl)carboxamido]phenyl)pyrimidine (2a) c

107 A antagonist, SB-699551 (3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[(4'-{[(2-phenylethyl)amino]methy

108 n of suitable Cu complexing ligands {tris[2-(dimethylamino)ethyl]amine (Me6TREN) and tris[(2-pyridyl)

109 ethoxygeldanamycin, and 17-demethoxy-17-[[2-(dimethylamino)ethyl]amino]-geldanamycin.

110 topoisomerase II inhibitor AQ4 [1,4-bis{[2-(dimethylamino)ethyl]amino}-5,8-dihydroxy-anthracene-9,10

111 based on the parent thioether 4,6-bis[4-[[2-(dimethylamino)ethyl]mercapto]phenyl]pyrimidine (1a) and

112 3] (M = Li, Na, K), characterized as tris{2-(dimethylamino)ethyl}amine (L) complexes [(L)M][HBPh3], a

113 crylate) block and a hydrophilic poly[N,N-2-(dimethylamino)-ethyl methacrylate) block (PMMA-b-PDMAEMA

114 hite light: (1) alpha-(DMEN)PbBr4 (DMEN = 2-(dimethylamino)ethylamine), which adopts a unique corruga

115 ntraperitoneally with an hsp90 inhibitor, 17-dimethylamino-ethylamino-17-demethoxygeldanamycin (17-DM

116 edioxythiophene) (PEDOT) treated by tetrakis(dimethylamino)ethylene (TDAE) have large n-type voltages

117 ation reagent derived from CF3I and tetrakis(dimethylamino)ethylene (TDAE) was found to be effective

118 ed by mixing C2F5I and n-C4F9I with tetrakis(dimethylamino)ethylene (TDAE) were effective in their nu

119 In this work, we utilized a 7-dimethylamino flavylium heterocycle to construct a panel

120 e dismutase, or NOX4 inhibitors fulvene-5, 6-dimethylamino-fulvene, and proton sponge blue.

121 of a salt bridge between the desosamine N,N-dimethylamino functionality of the natural substrate YC-

122 exposure to HCl vapor, which protonates the dimethylamino group and inhibits the electron-donating p

123 specific interactions between the protonated dimethylamino group and the acidic amino acid residues A

124 These advanced lead compounds possess a dimethylamino group at the 6 position.

125 uted with an electron withdrawing protonated dimethylamino group at the para position, hydrogen coord

126 subunit, (2) either an N-methylamino or N,N-dimethylamino group attached in a para orientation relat

127 A m-dimethylamino group is crucial to achieve high photochem

128 the more-hindered DA product 8 (ortho to the dimethylamino group) over the less-hindered product 9 (p

129 ver the less-hindered product 9 (para to the dimethylamino group), despite the higher energy TS for 8

130 ogen-bonding network with the deoxysugar C3' dimethylamino group.

131 nvolving replacement of the C8 methyl with a dimethylamino group.

132 ylidene ligand IPr((NMe2)2) incorporates two dimethylamino groups as backbone substituents enhancing

133 The number of amino-, methylamino-, and dimethylamino groups has a significant effect on these p

134 A disubstituted allene with two dimethylamino groups is the smallest studied superbase,

135 ve site metal via its hydrazide carbonyl and dimethylamino groups.

136 ketones, acetals, ethers, silyl ethers, and dimethylamino groups.

137 ar levels are controlled by dimethylarginine dimethylamino-hydrolase (DDAH).

138 Dimethylarginine-dimethylamino-hydrolase protein expression was reduced a

139 reakdown (decreased hepatic dimethylarginine-dimethylamino-hydrolase) and/or increased production.

140 goes hepatic metabolism via dimethylarginine-dimethylamino-hydrolase, and is derived by the action of

141 hyl)carbene]pentacarbonylchromium (3a), and [dimethylamino(iso-propyl)carbene]pentacarbonylchromium (

142 Sequential formation of dimethylamino isocyanate (Me2N-NCO), 1,1-dimethyldiazene

143 and UV excitation energies of the transient dimethylamino isocyanate and 1,1-dimethyldiazene have be

144 igand bears electronic similarities to the o-dimethylamino isomer, but it also possesses structural s

145 yl)cyclopent-2-ene-1-ylidene]chromi um (5), [dimethylamino(methyl)carbene]pentacarbonylchromium (3a),

146 s (24-56 y old) using (123)I-labeled 2-((2-((dimethylamino)methyl) phenyl)thio)-5-iodophenylamine (AD

147 y reported compounds of this series, 2-(2'-((dimethylamino)methyl)-4'-(2-(18)F-fluoroethoxy)phenylthi

148 hoxy)phenylthiol)benzenamine (1) and 2-(2'-((dimethylamino)methyl)-4'-(3-(18)F-fluoropropoxy)phenylth

149 2-(2'-((Dimethylamino)methyl)-4'-(4-(18)F-fluorobutoxy)phenylthi

150 toxy)phenylthiol)benzenamine (3) and 2-(2'-((dimethylamino)methyl)-4'-(5-(18)F-fluoropentoxy)phenylth

151 the 4'-position on phenyl ring B of 2-(2'-((dimethylamino)methyl)-4'-(fluoroalkoxy)phenylthio)benzen

152 The DoL of 2-[(dimethylamino)methyl]naphthalene (dman) that proceeds wi

153 (E = Ga; 79%) (Mamx = 2,4-di-tert-butyl-6-[(dimethylamino)methyl]phenyl) reacted with dilithioferroc

154 eceptor parameters with (11)C-3-amino-4-(2-[(dimethylamino)methyl]phenylthio)benzonitrile ((11)C-DASB

155 tor N-(3-chloro-4-methylphenyl)-N'-{2-[({5-[(dimethylamino)-methyl]-2-furyl}-methyl)- sulfanyl]ethyl}

156 The protein kinase C inhibitor 2-{8-[(dimethylamino)-methyl]-6,7,8,9-tetrahydropyrido[1,2-a]in

157 ring a methoxy, methylsulfanyl, methylamino, dimethylamino, methyl, or oxo group at position 6, or 2,

158 ased electron density in the vicinity of the dimethylamino moiety, for example induced by hydroxylati

159 permanent dipole moment, generated by an N,N-dimethylamino- moiety on one end of the car coupled with

160 yanthracene-9,10-dion e], a prodrug with two dimethylamino N-oxide groups, is converted to the topois

161 Mn(I) tricarbonyl complex with the ligand 5-(dimethylamino)-N, N-bis(pyridin-2-ylmethyl) naphthalene-

162 entification of the most active compound, 4-(dimethylamino)-N-(3-{2-[(4-oxo-4H-chromen-7-yl)oxy]aceta

163 mes greater than that determined for (E)-4'-(dimethylamino)-N-methyl-4-stilbazolium hexafluorophospha

164 e technologically important material (E)-4'-(dimethylamino)-N-methyl-4-stilbazolium tosylate; (ii) re

165 han that of the commercial chromophore E-4'-(dimethylamino)-N-methyl-4-stilbazolium.

166 AQ4N [1,4-bis{[2-(dimethylamino-N-oxide)ethyl]amino}-5,8-dihydroxyanthrace

167 crystallographic model of 1,1-dicyano-2-[6-(dimethylamino)naphthalen-2-yl]propene (DDNP) bound to an

168 a-e as mixed analogues of archetypal 1,8-bis(dimethylamino)naphthalene ("proton sponge") 1 and quino[

169 1,8-Bis(dimethylamino)naphthalene ("Proton Sponge") and bromomal

170 yl- and 2,7-dialkynyl derivatives of 1,8-bis(dimethylamino)naphthalene ("proton sponge") have been ob

171 3A4(C58,C64) labeled with 6-(bromoacetyl)-2-(dimethylamino)naphthalene (BADAN), 7-(diethylamino)-3-(4

172 tive of the superbasic proton sponge 1,8-bis(dimethylamino)naphthalene (DMAN) and covalently linked i

173 P), 3-hydroxypicolinic acid (3-HPA), 1,8-bis(dimethylamino)naphthalene (DMAN), 1,8,9-anthracentriol (

174 The strong non-nucleophilic base bis(dimethylamino)naphthalene (Proton Sponge, PS) has been f

175 attached to the prototype superbase 1,8-bis(dimethylamino)naphthalene 1 are examined using DFT metho

176 d full-length utrophin on 6-propionyl-2-(N,N-dimethylamino)naphthalene actin depolymerization.

177 The fluorescent amino acid 2-amino-3-(5-(dimethylamino)naphthalene-1-sulfonamide)propanoic acid (

178 ies 20 kcal mol(-1) greater than that of bis(dimethylamino)naphthalene.

179 y at room temperature, generating 3-(4,5-bis(dimethylamino)napthalen-1-yl)furan-2,5-dione (4-maleican

180 s of quinolinoquinolines functionalized with dimethylamino (NMe(2)), 1,1,3,3-tetramethylguanidino (N=

181 benzyl (Bz); pyridyl (Py); imidazolyl (Im); dimethylamino (NMe(2)); (tert-butylphenyl)pyridyl (TBP);

182 for 1b (amino oxide-o-carborane), 1i (di-N,N-dimethylamino-o-carborane), and 2g (di-N,N-diisopropylam

183 ) = 50 nM) and 21 (EC(50) = 90 nM) bearing a dimethylamino or piperidinyl group, respectively, at pos

184 e remaining PMO analogues having morpholino, dimethylamino, or N-methylamino phosphorodiamidate linka

185 oligonucleotides modified with 2'-O-[2-[(N,N-dimethylamino)oxy] ethyl] (2'-O-DMAOE) are described.

186 These studies identified an analog, dimethylamino-parthenolide (DMAPT), which induces rapid

187 We also identified 5-chloro-N-(4-(dimethylamino)phenethyl)-3-hexyl-1H-indole-2-carboxamide

188 bust CB1 allosteric modulator 5-chloro-N-(4-(dimethylamino)phenethyl)-3-pentyl-1H-indole-2-carboxamid

189 tent CB1 allosteric modulator 5-chloro-N-(4-(dimethylamino)phenethyl)-3-propyl-1H-indole-2-carboxamid

190 n of ML to its structural moieties (i.e., 4-(dimethylamino)phenol (DAP) and (8-aminoquinolin-2-yl)met

191 descending rank order for cytotoxicity was 3-dimethylamino-phenol > 2,2,6,6-tetramethyl-4-piperidone

192 dition products, two of which (involving the dimethylamino phenyl unit) are shown to form in a nonsta

193 istical dynamics in the cyclization onto the dimethylamino phenyl unit, though.

194 properties of dipolar chromophores having 4-(dimethylamino)phenyl electron donor (D) and pyridinium a

195 The cycloadducts with a 4-(dimethylamino)phenyl group on the maleimide nitrogen ato

196 The 3-(dimethylamino)phenyl groups at the alpha position prove

197 -neutral phenyl groups, electron-rich 4-(N,N-dimethylamino)phenyl substituents, and electron-poor pyr

198 The fluorescent substrate 4-(4-(dimethylamino)phenyl)-1-methylpyridinium (APP(+)) exhibi

199 ide uses a fluorescein isothiocyanate/4-((4-(dimethylamino)phenyl)azo) benzoic acid (FITC/DABCYL) FRE

200 N,N'-((4-(Dimethylamino)phenyl)methylene)bis(2-phenylacetamide) wa

201 oid receptor (GR) antagonist (11, 17)-11-[4-(dimethylamino)phenyl]-17-hydroxy-17-(1-propynyl)estra-4,

202 ogical blockade of PRs by RU-486 [11beta-[p-(dimethylamino)phenyl]-17beta-hydroxy-17-(1-propynyl)estr

203 e effects was inhibited by RU486 (11beta-[p-(dimethylamino)phenyl]-17beta-hydroxy-17-(1-propynyl)estr

204 r antagonist RU486 [mifepristone (11beta-[p-(dimethylamino)phenyl]-17beta-hydroxy-17-(1-propynyl)estr

205 lation was inhibited using RU486 (11beta-[p-(Dimethylamino)phenyl]-17beta-hydroxy-17-(1-propynyl)estr

206 [4-(1H-Imidazol-4-yl)butyl]-4-{(1E,3E)-4-[4-(dimethylamino)phenyl]buta-1,3-dienyl}-2,6-dimethylpyridi

207 Using this strategy, two compounds 2-[4-(dimethylamino)phenyl]imidazo[1,2-a]pyridine-8-ol (1) and

208 6-heptatrienal (AR-3) and 3,7-dimethyl-9-(4'-dimethylamino-phenyl)-2,4,6,8-nonatetraenal (AR-4), and

209 and two new retinal analogs, 3-methyl-7-(4'-dimethylamino-phenyl)-2,4,6-heptatrienal (AR-3) and 3,7-

210 One compound, (Z)-3-(4-dimethylamino-phenyl)-2-phenyl-acrylonitrile, was used f

211 (123)I-IMPY (6-iodo-2-(4'-dimethylamino-)phenyl-imidazo[1,2-a]pyridine) is a novel

212 0 of cTnI and the nonfluorescent acceptor 4-(dimethylamino)phenylazophenyl-4'-maleimide (DABM) attach

213 various numbers of electron-donating 4-(N,N-dimethylamino)phenylethynyl (1-4) or electron-withdrawin

214 6-Thiolato-substituted 2-(4'- N,N-dimethylamino)phenylimidazo[1,2- a]pyridines ( RS-IMPYs;

215 The diol was reacted with tris(dimethylamino)phosphane and consecutively with H2(17)O t

216 Only basic phosphines, such as tris(dimethylamino)phosphine, allow for the synthesis of a st

217 on led to the identification of 1,1'-bis[bis(dimethylamino)phosphino]ferrocene "DMAPF", a readily ava

218 le reaction with 1H-benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate (BOP) and

219 ides and ureas with benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate (BOP), bas

220 nucleosides and 1H-benzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate (BOP).

221 t has been found that 1,4-butanediylbis[tris(dimethylamino)]phosphonium dication is a very efficient

222 ive fluorescent amino acids derived from the dimethylamino-phthalimide family.

223 ly efficacious PI3K/mTOR inhibitor 1-(4-{[4-(dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-

224 Additionally the N,N-dimethylamino PMO-DNA chimeras were found to stimulate R

225 nd, N-(4-(3-bromoanilino)quinazolin-6-yl)-3-(dimethylamino)propanamide (5), did not show covalent bin

226 identified two compounds, AT791 {3-[4-(6-(3-(dimethylamino)propoxy)benzo[d]oxazol-2-yl)phenoxy]-N,N-d

227 le myofibrils cross-linked with 1-ethyl-3-[3(dimethylamino) propyl] carbodiimide to prevent shortenin

228 n-based ligand that contains a hemilabile 3-(dimethylamino)propyl substituent.

229 (+/-)-Citalopram (1, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisob

230 ary development of our lead 2-cyano-3-(1-(3-(dimethylamino)propyl)-2-methyl-1H-indol-3-yl)-N-octylacr

231 pCB-coated surface via simple 1-ethyl-3-(3-(dimethylamino)propyl)-carbodiimide and N-hydroxysuccinim

232 S11 antibodies (Ab-MB) by EDC (1-ethyl-3-(3-(dimethylamino)propyl)-carbodiimide)/NHS ( N-hydroxysulfo

233 h the carboxylic acid activator 1-ethyl-3-(3-dimethylamino)propyl)carbodiimide (EDC) and the catalyst

234 ailable peptide coupling agent 1-ethyl-3-(3-(dimethylamino)propyl)carbodiimide (EDC).

235 le cross-linking protocol with 1-ethyl-3-(3-(dimethylamino)propyl)carbodiimide (EDC).

236 t carboxylic residues, whereby 1-ethyl-3-(3-(dimethylamino)propyl)carbodiimide activates a carboxyl g

237 1,3-indandione-1-hydrazone and 1-ethyl-3-(3-(dimethylamino)propyl)carbodiimide.

238 ite electrode (PGE) by coupling agents of N-(dimethylamino)propyl-N'-ethylcarbodiimide hydrochloride

239 nonselective PKC inhibitor Go6983 (3-[1-[3-(dimethylamino)propyl]-5-methoxy-1H-indol-3-yl]-4-(1H-ind

240 ining molecules on tissue with 1-ethyl-3-[3-(dimethylamino)propyl]-carbodiimide hydrochloride and (ii

241 asic than parental superbase N,N',N"-tris[(3-dimethylamino)propyl]-guanidine (tris-DMPG), whereas est

242 [Cu(I)(MeAN)](+) (MeAN = N-methyl-N,N-bis[3-(dimethylamino)propyl]amine) leads to a low-temperature s

243 ](2+) ((S)P(MeAN), MeAN: N-methyl-N,N-bis[3-(dimethylamino)propyl]amine) that featured an elongated O

244 h the zero-length cross-linker 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide (EDC) and analyzed by

245 1-Ethyl 3-[3-(dimethylamino)propyl]carbodiimide (EDC) was found to pro

246 ne side chain of lisinopril by 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide hydrochloride/N-hydrox

247 N-octylacrylamide (2) confirmed the tertiary dimethylamino-propyl moiety as critical for inhibition o

248 e identification of compound OL-1 (2-(11-(3-(dimethylamino)propylidene)-6,11- dihydrodibenzo[b,e]oxep

249 itive poly(N-isopropylacrylamide)-co-(3-(N,N-dimethylamino)propylmethacrylamide) microgel (poly(NIPAM

250 pyridine] has been prepared from 3-lithio-4-(dimethylamino)pyridine (5) and triphenylacetaldehyde (3)

251 Acyl pyridinium salts derived from 4-(dimethylamino)pyridine (DMAP) and benzoic anhydride are

252 4-(N,N-Dimethylamino)pyridine (DMAP) and benzyltrimethylammoniu

253 iting diverse reactivity with phosphines, 4-(dimethylamino)pyridine (dmap) and chlorophosphines, prov

254 he complex 8 of isopinocampheylborane and p-(dimethylamino)pyridine (DMAP) can be obtained with >99%

255 d)(PPh(3))(2) (nbd = 2,5-norbornadiene)/N,N-(dimethylamino)pyridine (DMAP) catalyzed polymerization o

256 ssisted heating and a catalytic amount of 4-(dimethylamino)pyridine (DMAP) further improved the yield

257 oup on each blade of the triptycene and a 4-(dimethylamino)pyridine (DMAP) unit to selectively delive

258 nion binding catalyst in combination with 4-(dimethylamino)pyridine (DMAP), both employed at a 5 mol

259 nor ligands (1-methylimidazole [MIM], 4-(N,N-dimethylamino)pyridine [DMAP], pyridine, and 1-octylimid

260 ting the kinetics of the reaction between 4-(dimethylamino)pyridine and DCM.

261 rough the interplay of benzoic anhydride, 4-(dimethylamino)pyridine as a nucleophilic catalyst, and a

262 The cation forms a Lewis adduct with 4-(N,N-dimethylamino)pyridine but a frustrated Lewis pair (FLP)

263 ional and the experimental data for the N,N-(dimethylamino)pyridine compound demonstrate nearly isoen

264 nd (3) either an N-methylaniline or a 2-(N,N-dimethylamino)pyridine ring.

265 Alternatively, addition of DMAP (DMAP = 4-(dimethylamino)pyridine) to [2](+) results in coordinatio

266 Ph2 NSiMe3)2; Mes = 2,4,6-Me3C6H2; DMAP = 4-(dimethylamino)pyridine) which exhibits the unprecedented

267 Using 4-(dimethylamino)pyridine, a corresponding Lewis-base adduc

268 Lewis bases [THF, 4-(dimethylamino)pyridine, and PMe(3)] coordinate to the si

269 FeL(n) (L = N(2), n = 1,2; CO, n = 2; 4-(N,N-dimethylamino)pyridine, n = 1) resulted in a doubly redu

270 c Zn and either 1,5-cyclooctadiene or 4-(N,N-dimethylamino)pyridine.

271 a(2)-(2-trifluoromethyl)pyridine) (DMAP = 4-(dimethylamino)pyridine; Tp = tris(pyrazolyl)borate) is d

272 AP [1, 3-(2,2,2-triphenyl-1-acetoxyethyl)-4-(dimethylamino)pyridine] has been prepared from 3-lithio-

273 chloride in CH(2)Cl(2) in the presence of 4-(dimethylamino)-pyridine (DMAP) plus N,N-diisopropylethyl

274 ullerene-carboxylic acid (C60A) and either a dimethylamino-pyridine (DMAP) or a phenothiazine-pyridin

275 Here we use this substrate, 4-(4-(dimethylamino)styrl)-N-methyl-pyridinium (ASP+), in comb

276 opamine (DA) transporter (DAT), termed 4-(4-(dimethylamino)styryl)-N-methylpyridinium (ASP+), to illu

277 using a fluorescent substrate of DAT, 4-(4-(dimethylamino)styryl)-N-methylpyridinium (ASP+).

278 the fluorescent DAT substrate ASP(+) [4-(4-(dimethylamino)styryl)-N-methylpyridinium] revealed that

279 y of the 4-(di-cyanomethylene)-2-methyl-6-p-(dimethylamino)styryl-4H-pyran (DCM) laser dye in deutera

280 t dopamine transporter substrate trans-4-[4-(dimethylamino)styryl]-1-methylpyridinium (ASP(+)) in hum

281 Fluorescent dye trans-2-[4-(dimethylamino)styryl]-3-ethyl-1,3-benzothiazolium perchl

282 dition of electron-donating groups such as a dimethylamino substituent at the 7 position greatly enha

283 Under neutral conditions, the dimethylamino substituent coordinates to the ruthenium c

284 is achieved by a combined ortho-CN and meta-dimethylamino substituent electronic effect that largely

285 Mechanistic studies show that the dimethylamino substituent is partially dissociated from

286 d by molecular modeling, we replaced the N,N-dimethylamino substituents in tetramethylrhodamine with

287 Methyl or dimethylamino substituents increased the proton affinity

288 -9,10-dione] by reduction of the N-oxides to dimethylamino substituents.

289 tics of the benzoate transfer from the bis(4-dimethylamino)-substituted benzhydryl benzoate Ar(2)CH-O

290 Compound 9u (with a dimethylamino substitution) was the most active inhibito

291 sults led to the finding that daminozide (N-(dimethylamino)succinamic acid, 160 Da), a plant growth r

292 alkenylsilane reagents and 1.5 equiv of tris(dimethylamino)sulfonium difluorotrimethylsilicate (TASF)

293 on will form by reaction of silane with tris(dimethylamino)sulfonium difluorotrimethylsilicate (TASF)

294 Structural studies confirmed this N,N-dimethylamino tail moved toward the DFG motif to form a

295 Indeed, introduction of an N,N-dimethylamino tail resulted in 4b, which showed almost 5

296 nctional-group tolerant, with alkene, ether, dimethylamino, trifluoromethyl, ester, cyano, halide, hy

297 type urea-thiourea catalysts bearing a basic dimethylamino unit by a combination of X-ray crystallogr

298 moted aza-Diels-Alder reaction between 6-[2-(dimethylamino)vinyl]-1,3-dimethyluracil and aldimines ha

299 By changing the dimethylamino with the cyano group, a dendrimeric molecu

300 sisting of triazacryptand coupled to 3,6-bis(dimethylamino)xanthylium, whose fluorescence increased 1