ライフサイエンスコーパス: dinitrobenzene

1 covered and designated ROD1 (resistance to o-dinitrobenzene).

2 -1 for the native enzyme toward 1-chloro-2,4-dinitrobenzene.

3 e experimental contact allergen 1-fluoro-2,4-dinitrobenzene.

4 nzyme's preferred substrate is 1-chloro-2, 4-dinitrobenzene.

5 glutathione sulfonic acid, and glutathione-s-dinitrobenzene.

6 to discriminate between the three isomers of dinitrobenzene.

7 esized bearing 1 to 4 sulfonamide-linked 2,4-dinitrobenzene.

8 ,3,5-trinitro-1,3,5-triazinane, and DNB: 1,3-dinitrobenzene.

9 ding unique responses for dinitrotoluene and dinitrobenzene.

10 ect transferase activity toward 1-chloro-2,4-dinitrobenzene.

11 xed saturating concentration of 1-chloro-2,4-dinitrobenzene.

12 rom that of monobromobimane and 1-chloro-2,4 dinitrobenzene.

13 elated to substrates, including 1-chloro-2,4-dinitrobenzene.

14 ted by the GSH-specific reagent 1-chloro-2,4-dinitrobenzene.

15 d reductive cyclization of 1,4-dialkenyl-2,3-dinitrobenzenes.

16 The electrochemistry of 1,2-dinitrobenzene (1,2-DNB), 1,3-dinitrobenzene (1,3-DNB),

17 Normalized response profiles for 1,3-dinitrobenzene (1,3-DNB) are independent of analyte conc

18 emistry of 1,2-dinitrobenzene (1,2-DNB), 1,3-dinitrobenzene (1,3-DNB), and 1,4-dinitrobenzene (1,4-DN

19 -DNB), 1,3-dinitrobenzene (1,3-DNB), and 1,4-dinitrobenzene (1,4-DNB) is strongly affected by the pre

20 itrotoluene (7.9 +/- 4.0) x 10(6) M(-1); 1,3-dinitrobenzene (1.0 +/- 0.7) x 10(6) M(-1); and 2,4-dini

21 xide diamine (HMTD), 2,4-dinitrotoluene, 1,3-dinitrobenzene, 1,3,5-trinitrobenzene, 2-amino-4,6-dinit

22 dinitroaromatic radical anions (1,2- and 1,4-dinitrobenzene, 1,5- and 2,6-dinitro naphthalene, 4,4'-d

23 ocalized) intervalence radical anions of 1,4-dinitrobenzene, 2,6-dinitronaphthalene, 2,6-dinitroanthr

24 inity peptide tag, (64)Cu-L19K-(5-fluoro-2,4-dinitrobenzene) ((64)Cu-L19K-FDNB), which binds covalent

25 ddition of glutathione (GSH) to 1-chloro-2,4-dinitrobenzene, a reaction in which the chemical step is

26 eater than marginal activity with chloro-2,4 dinitrobenzene activity also exhibited significant activ

27 Cells treated with 1-chloro-2,4-dinitrobenzene, an irreversible inhibitor of thioredoxin

28 response is obtained for the explosives 1,3-dinitrobenzene and 2,4-dinitrotoluene over the 200-1,400

29 emically distinct sensitizers; 1-fluoro-2, 4-dinitrobenzene and 2-deoxyurushiol.

30 th 92% residual activity toward 1-chloro-2,4-dinitrobenzene and completely blocks Cys111 from subsequ

31 appreciable changes in K(m) for 1-chloro-2,4-dinitrobenzene and have similar CD spectra to that of wi

32 omatic compounds (1,3,5 trinitrobenzene, 1,3 dinitrobenzene, and 2,4 dinitrotoluene) and electronic s

33 a12,14-prostaglandin-J2, menadione, 1-Cl-2,4-dinitrobenzene, and biotinylated iodoacetamide.

34 cal inhibitor of Trx reductase, 1-chloro-2,4-dinitrobenzene, and Trx1 siRNA.

35 ith CuCN x 2LiBr and then oxidizing with 1,3-dinitrobenzene, and was used in a diversity-oriented syn

36 25 M(-1) s(-1)) compared to that of the 1,2-dinitrobenzene ( approximately 5 M(-1) s(-1)), whereas t

37 ic substrate sites (such as for 1-chloro-2,4-dinitrobenzene) are predominantly located within each su

38 With 1-chloro-2, 4-dinitrobenzene as a substrate, the His107 residue primar

39 tt2p exhibit GST activity with 1-chloro-2, 4-dinitrobenzene as a substrate.

40 nits/mg of cytosolic protein, using 1-Cl-2,4-dinitrobenzene as substrate), resulted in 70-90% reducti

41 tivities toward dimethenamid or 1-chloro-2,4-dinitrobenzene as substrates and in their levels of indu

42 We demonstrate the utility of 4,5-o-dinitrobenzenes as relatively stable precursors to this

43 enzyme was highly active toward 1-chloro-2,4-dinitrobenzene, as well as chloroacetanilide herbicides.

44 uctase, including auranofin and 1-chloro-2,4-dinitrobenzene, attenuated H(2)O(2) removal rates in mit

45 ncrease in GST activity toward 1-chloro-2, 4-dinitrobenzene but GST activity toward 4-HNE was increas

46 1,5-Bis-(dihexyl-N-nitrosoamino)-2,4-dinitrobenzene (C6') and an inactive form of the compoun

47 of the compound [1,5-bis-(dihexylamino)-2,4-dinitrobenzene (C6)] were tested in neuronal cell cultur

48 ls of enzymatic activity toward 1-chloro-2,4-dinitrobenzene (CDNB) and HNE were present in normal ste

49 is based on competition between 1-chloro-2,4-dinitrobenzene (CDNB) and the drugs for the GST enzyme i

50 exhibited high activity with 1-chloro-2, 4, dinitrobenzene (CDNB) but low activity with the chloroac

51 eaction between glutathione and 1-chloro-2,4-dinitrobenzene (CDNB) is widely used as a standard activ

52 When the general substrate 1-chloro-2-4-dinitrobenzene (CDNB) was used to assess GST activity wi

53 ly) the canonical GST substrate 1-chloro-2,4-dinitrobenzene (CDNB), and bear a wide variety of bioort

54 mmonly used synthetic substrate 1-chloro-2,4-dinitrobenzene (CDNB), but has relatively high glutathio

55 1-Chloro-2,4-dinitrobenzene (CDNB), which causes oxidative stress thr

56 in the crystal between GSH and 1-chloro-2,4-dinitrobenzene (CDNB).

57 with respect to turnover with 1-chloro-2, 4-dinitrobenzene (CDNB).

58 GSH but not for the cosubstrate 1-chloro-2,4-dinitrobenzene (CDNB).

59 hionine S,R-sulfoximine (BSO); 1-chloro, 2,4-dinitrobenzene (CDNB); or 1,3-bis (2-chloroethyl)-1-nitr

60 porter gene to screen a 1,5-dialkylamino-2,4-dinitrobenzene combinatorial chemical library consisting

61 The 1-fluoro-2,4-dinitrobenzene-conjugated dendritic cells that had been

62 P70 produced a reduction in the 1-fluoro-2,4-dinitrobenzene contact hypersensitivity response and res

63 pi-pi EDA interactions of dinitrobenzene contribute -17 to -19 kJ/mol (3-3.4 log u

64 droxysuccinimide ester and 1,5-difluoro-2, 4-dinitrobenzene cross-linked BK to the wild-type human B2

65 pproximately 5 M(-1) s(-1)), whereas the 1,4-dinitrobenzene did not show any proton transfer effect i

66 Exposure to 1,3-dinitrobenzene (DNB) is associated with neuropathologic

67 The location of the dinitrobenzene (DNB) ring in the GSDNB-GSTM2-2 complex w

68 rinitrobenzene (TNB), trinitrotoluene (TNT), dinitrobenzene (DNB), tetryl, and 2,4-dinitrotoluene (2,

69 he redox potentials of compounds such as 1,4-dinitrobenzene (DNB), which can be reduced in two one-el

70 roteins as a function of sensitivity to 1, 3-dinitrobenzene (DNB)-induced mitochondrial permeability

71 respect to their response to the toxicant m-dinitrobenzene (DNB).

72 carboxylic acid electron acceptors including dinitrobenzenes (DNBs) and naphthalenediimide (NI), whic

73 report that a contact allergen, 1-chloro-2,4-dinitrobenzene (DNCB), elicits contact hypersensitivity

74 or the Trx reductase inhibitor 1-chloro-2,4-dinitrobenzene (DNCB), in embryonic rat heart (H9c2) cel

75 ation with the contact allergen 1-fluoro-2,4-dinitrobenzene (DNFB) resulted in epidermal accumulation

76 Chronic application of 1-fluoro-2,4-dinitrobenzene (DNFB) to carcinogen-treated skin led to

77 AN9 toward the common substrate 1-chloro 2,4-dinitrobenzene, equilibrium dialysis, and tryptophan que

78 s more than 50-fold greater for 1-fluoro-2,4-dinitrobenzene (FDNB), and the product is the same for b

79 trate-dependent; in contrast to 1-chloro-2,4-dinitrobenzene, for the nucleophilic addition reaction o

80 nated peptide ions and radical anions of 1,3-dinitrobenzene formed exclusively c- and z-type fragment

81 ed sorption of benzene, naphthalene, and 1,4-dinitrobenzene from water to a series of wood chars made

82 hGSTM1a-1a complexed with 1-glutathionyl-2,4-dinitrobenzene (GS-DNB) formed by a reaction in the crys

83 nto DTY167 cells alleviates the 1-chloro-2,4-dinitrobenzene-hypersensitive phenotype concomitant with

84 active site alters affinity for 1-chloro-2,4-dinitrobenzene in the active site of the other subunit.

85 red forms by potassium-mirror reduction of p-dinitrobenzene in the presence of macrocyclic polyether

86 catalyze conjugation of GSH to 1-chloro-2,4-dinitrobenzene, indicating an absence of microsomal glut

87 tely inhibited activity toward 1-chloro-2, 4-dinitrobenzene, indicating that AFB-GSH binding to one a

88 t release is rate-limiting when 1-chloro-2,4-dinitrobenzene is the substrate.

89 In particular, the 1,3-dinitrobenzene isomer showed a higher proton transfer ra

90 d of electrogenerated dianionic species from dinitrobenzene isomers and substituted dihomooxacalix[4]

91 the complete discrimination of very similar dinitrobenzene isomers and three halogenated, substitute

92 The electron-withdrawing nature of the dinitrobenzene moieties can trigger the intramolecular H

93 Both mutants handle substrate 1-chloro-2,4-dinitrobenzene normally; however, Y103S exhibits a 30-fo

94 ein that is induced when the GST substrate o-dinitrobenzene (o-DNB) is added to the culture.

95 plosives-related compounds nitrobenzene, 1,3-dinitrobenzene, o-nitrotoluene, 2,4-dinitrotoluene, and

96 vity (induced by treatment with 1-chloro-2,4-dinitrobenzene) or brush stimulation-induced AD-like ski

97 oluene, 2,6-dinitrotoluene, trinitrobenzene, dinitrobenzene, or 1,3,5-trinitro-1,3,5-triazacyclohexan

98 -transfer rates for the potassium salts of p-dinitrobenzene radical anion (DNB(-)).

99 ar unsymmetrical gas-phase structure for 1,3-dinitrobenzene radical anion but give serious spin conta

100 romyces cerevisiae leads to an increase in o-dinitrobenzene resistance in S. cerevisiae cells.

101 thione (GSH), by treatment with 1-chloro-2,4-dinitrobenzene, resulted in increased dense cells.

102 control, L19K was conjugated to 1-fluoro-2,4-dinitrobenzene, resulting in L19K-DNP.

103 dynein and myosin V using 1,5-difluoro-2, 4-dinitrobenzene revealed that this light chain exists as

104 n as that of the enzyme-GSH complex, and the dinitrobenzene ring is anchored between the side chains

105 minobenzoic acid substituent is bound to the dinitrobenzene ring via its carboxyl oxygen while the ot

106 diaminobenzoquinone diimine units linked by dinitrobenzene rings, are synthesized by selective oxida

107 On percutaneous immunization to 1-fluoro-2,4-dinitrobenzene, stimulated CD4(+) T cells from draining

108 nin-specific TH1 clone) or with 5S8 T cells (dinitrobenzene sulfonate specific Th0 clone) in the pres

109 induced with dextran sulfate sodium (DSS) or dinitrobenzene sulfonic acid (DNBS) in mice treated with

110 e mice significantly reduced the severity of dinitrobenzene sulfonic acid (DNBS)-, oxazolone-, and de

111 2,4-Dinitrobenzene sulfonic acid (DNBS)-induced colitis is a

112 Adoptive transfer of 2,4-dinitrobenzene sulfonic acid (DNBS)-pulsed DCs directly

113 gnificantly increased in colon tissues after dinitrobenzene sulfonic acid administration.

114 mononuclear cells (PBMCs)-DCs) treated with dinitrobenzene sulfonic acid for predicting skin-sensiti

115 of peripheral organ inflammation (i.e., 2,4-dinitrobenzene sulfonic acid-induced colitis).

116 is induced by intracolonic administration of dinitrobenzene sulfonic acid.

117 aced more effectively by the pi acceptor 2,4-dinitrobenzene than by the pi donor naphthalene.

118 lly if at all hypersensitive to 1-chloro-2,4-dinitrobenzene, the most commonly used substrate for glu

119 H(ab) values range from 5410 cm(-)(1) (1,4- dinitrobenzene) to 3400 cm(-)(1) (9,9-dimethyl-2,7-dinit

120 performed with a series of dinitrotoluenes, dinitrobenzene, trinitrotoluene, trinitrobenzene, two am

121 tal hepatic GST activity toward 1-chloro-2,4-dinitrobenzene was also significantly decreased.

122 1,5-difluoro-2,4-dinitrobenzene was conjugated at the C-terminal lysine f

123 Cross-linking the dimer by 1,5-difluoro-2,4-dinitrobenzene was inhibited by ATP, dATP, dGTP, and dAd

124 ita-Stille cross coupling of 1,4-dibromo-2,3-dinitrobenzene with an alkenyltin reagent to give symmet