ライフサイエンスコーパス: dinitrophenol

1 nilyl) and at the other end with a quencher (dinitrophenol).

2 pylamine incorporation, visualized with anti-dinitrophenol.

3 and removal of the mitochondrial poison 2,4 dinitrophenol.

4 opy of subunits complexed with antibodies to dinitrophenol.

5 6.5, not at pH 8.0, and were not induced by dinitrophenol.

6 se matched proteins induced by the uncoupler dinitrophenol.

7 pleted of energy with 2-deoxyglucose and 2,4-dinitrophenol.

8 is very much larger than that of 2,4- or 2,5-dinitrophenol (0.09 and 0.11), indicating a very much re

9 The hydrogen bond acidity of 2,3-dinitrophenol (0.67) is very much larger than that of 2,

10 luoromethoxy-phenylhydrazone (1-3 nM) or 2,4-dinitrophenol (100 nM) significantly antagonized and del

11 hibitors noeuromycin, mannoimidazole, or 2,4-dinitrophenol 2-deoxy-2-fluoro-mannoside reveal the resi

12 the genes involved in the degradation of 2,4-dinitrophenol (2,4-DNP) in a Rhodococcus erythropolis st

13 The separation of 4-nitrophenol, 2,4-dinitrophenol, 2-methyl-4-nitrophenol, 3-methyl-4-nitrop

14 the inhibitors, conduritol beta-epoxide and dinitrophenol-2-deoxy-2-fluoro-beta-D-glucopyranoside (D

15 environment on the rate of photolysis of 2,4-dinitrophenol (24-DNP), an important environmental toxin

16 photolysis of 4-nitrocatechol (4NC) and 2,4-dinitrophenol (24DNP) in semisolid isomalt as a new type

17 yanide m-chlorophenylhydrazone, 44%, and 2,4-dinitrophenol, 26%), by sodium azide (25%), and hydroxyl

18 benzene (1.0 +/- 0.7) x 10(6) M(-1); and 2,4-dinitrophenol (5.1 +/- 3.0) x 10(4) M(-1).

19 on of HTC hepatoma cells by exposure to 2, 4-dinitrophenol (50 microM) and 2-deoxy-D-glucose (10 mM)

20 Cells were exposed to dinitrophenol (50 microM) and 2-deoxyglucose (10 mM) as

21 ilar but much smaller effect occurs with 2,6-dinitrophenol (A = 0.17).

22 e (AICAR), rotenone (a Complex I inhibitor), dinitrophenol (a mitochondrial uncoupler), muscle contra

23 For instance, aqueous 2,4-dinitrophenol absorption varies dramatically over the pH

24 COUPY-caged version of the protonophore 2,4-dinitrophenol allowed us to confirm by confocal microsco

25 loped method can be used to detect trace 2,4-dinitrophenol, an explosive, with a limit of detection a

26 growth conditions in the presence of 0.1 mM dinitrophenol, an uncoupler of ATP synthesis.

27 somes is ATP-dependent, and ATP depletion by dinitrophenol and 2-deoxyglucose also inhibited apoB deg

28 s potent than the prototypical uncoupler 2,4-dinitrophenol and phenocopies 2,4-dinitrophenol in lower

29 io calculations which show that 2,3- and 2,6-dinitrophenol and picric acid are significantly distorte

30 o resolve time-depending binding between 2,4-dinitrophenol and transthyretin, and analyze biologicall

31 The dinitrophenols and picric acid are similarly discussed.

32 lex 1 inhibitor (rotenone) and an uncoupler (dinitrophenol) and by overexpression of mGPDH, which low

33 nic acid), electrophilic substrate analogue (dinitrophenol), and product analogues (S-hexylglutathion

34 ropic agent chloroquine, the energy depleter dinitrophenol, and also by low temperature, suggesting t

35 m: carbonyl cyanide p-chlorophenylhydrazone, dinitrophenol, and azide inhibited Hst 5 killing of Cand

36 Carbonyl cyanide p-chlorophenylhydrazone, dinitrophenol, and azide inhibited Hst 5-induced ATP eff

37 cell lines or colonic biopsy specimens using dinitrophenol, and barrier function was assessed by tran

38 ated that sodium salicylate, plumbagin, 2, 4-dinitrophenol, and menadione-inducers of the marRAB oper

39 arbonyl cyanide m-chlorophenylhydrazone, 2,4-dinitrophenol, and nigericin but not by the potassium io

40 -hydroxy-2-nonenal (HNE) -modified proteins, dinitrophenol, and nitrotyrosine to quantify and localiz

41 amino acid secretions was verified using 2,4-dinitrophenol as an inhibitor of the proton motive force

42 2-aminobenzyl-GGFLRKVGQ-ethylenediamine-2,4-dinitrophenol at the R-K bond, exhibiting a K(m) of 13 m

43 A mitochondrial uncoupler, 2,4-dinitrophenol (at 1 mmol/L), blocked the effects of 8-Br

44 ress and the mitochondrial uncoupling agent, dinitrophenol, both of which lead to increased glucose t

45 yanide m-chlorophenylhydrazone) and DNP (2,4-dinitrophenol) but completely inhibited by cyanide.

46 ol C6H5NO4, methylnitrocatechol C7H7NO4, and dinitrophenol C6H4N2O5) measured with a micro-orifice vo

47 of these cells by macrophages; and (3) that dinitrophenol can be used as a surrogate for quantitatin

48 bind putative ligands of the EmrAB pump-2,4-dinitrophenol, carbonyl cyanide m-chlorophenylhydrazone,

49 ing of a haptenated fluorescent protein, 2,4-dinitrophenol-coupled B-phycoerythrin (DNP25-PE), to flu

50 Both 2,4-dinitrophenol (DNP) and carbonyl cyanide p-trifluorometh

51 I(H) is induced by protonophores such as 2,4-dinitrophenol (DNP) and cyanide-4-(trifluoromethoxy) phe

52 e observed with the metabolic inhibitors 2,4-dinitrophenol (DNP) and sodium azide.

53 A23187 and the mitochondrial uncoupler, 2,4-dinitrophenol (DNP) as damaging agents.

54 n be quenched by both the negatively charged dinitrophenol (DNP) derivative, (DNP-BS(-)), and positiv

55 The mitochondrial protonophore 2,4 dinitrophenol (DNP) has beneficial effects on NAFLD, ins

56 on of the mitochondrial uncoupling agent 2,4-dinitrophenol (DNP) in a large animal model with minimum

57 efficacy of the mitochondrial uncoupler 2,4-dinitrophenol (DNP) in animals receiving striatal inject

58 Among these species, 2,4-dinitrophenol (DNP) is toxic to both plants and animals

59 Metformin increased PCr recovery from either dinitrophenol (DNP) or azide in L6 cells.

60 vical spinal cord transection, NaCN and also dinitrophenol (DNP) significantly (P < 0.05) elevated rC

61 od are demonstrated using the binding of 2,4-dinitrophenol (DNP) to transthyretin (TTR), as well as p

62 The chemical uncoupler 2,4-dinitrophenol (DNP) was an effective and widely used wei

63 the presence of the mitochondrial uncoupler dinitrophenol (DNP) were compared using 16.4 T in isoflu

64 itro explosives, i.e., picric acid (PA), 2,4-dinitrophenol (DNP), and nitrophenol (NP), via the fluor

65 III, or by the mitochondrial uncoupler, 2,4-dinitrophenol (DNP), indicating ATP depletion causes the

66 onyl cyanide m-chlorophenylhydrazone (CCCP), dinitrophenol (DNP), or CN(-), resulted in massive disso

67 of increased UCP3 expression), and acute 2,4-dinitrophenol (DNP)-treated (protonophore and mitochondr

68 athway in homogeneous solution, produces 2,4-dinitrophenol (DNP).

69 s was induced by addition and removal of 2,4-dinitrophenol (DNP).

70 ole-cell recordings, bath application of 2,4-dinitrophenol (DNP, an uncoupler of mitochondrial ATP pr

71 CsA, 42.6+/-9.0% with SfA; P<0.001), or 2,4-dinitrophenol (DNP, the mitochondrial uncoupler, 50 micr

72 acetate (IAA; glycolysis inhibitor) plus 2,4-dinitrophenol (DNP; oxidative phosphorylation inhibitor)

73 surface-bound IgG molecules (on various 2,4-dinitrophenol [DNP]-coated surfaces and pathogenic Staph

74 Mitochondrial superoxide evoked by dinitrophenol elicited significant internalization and t

75 -N-oxide and 2-[1-(p-chlorophenyl)ethyl] 4,6-dinitrophenol establish that both inhibitors block the b

76 e heat shock response, including salicylate, dinitrophenol, ethanol, and arsenite, have no effect on

77 disease, and the mitochondrial uncoupler 2,4-dinitrophenol for obesity.

78 PH), a primary antibody specific for the 2,4-dinitrophenol group, and a peroxidase-labeled second ant

79 AMPK activator dinitrophenol had effects on ERK, aPKCs, and 2-DOG uptak

80 ans blue dye in mice passively sensitized to dinitrophenol-human serum albumin and challenged intrade

81 so studied in mice passively sensitized with dinitrophenol-human serum albumin and challenged intrade

82 ctivation by the lipophilic protonophore 2-4 dinitrophenol in a pH-dependent manner.

83 oupler 2,4-dinitrophenol and phenocopies 2,4-dinitrophenol in lowering de novo lipogenesis and mitoch

84 ophilic analog of the uncoupler compound 2,6-dinitrophenol, in which a C8-hydrocarbon chain was conju

85 onstant for 3 hours and that exposure to 2,4-dinitrophenol increased QO2.

86 We have previously reported that 2-alkyl-4,6-dinitrophenols inhibit mammalian complexes I, II, and II

87 ide-4-(trifluoromethoxy) phenylhydrazone and dinitrophenol inhibited inositol transport by 50-70% in

88 nide-4-(trifluoromethoxy)phenylhydrazone and dinitrophenol inhibited inositol transport by 50-70% in

89 of the substituent in the 2-position of the dinitrophenol inhibitors.

90 stearoyl-oleoyl-phosphatidylcholine plus 3% dinitrophenol-linked di-oleoyl-phosphatidylethanolamine.

91 lic cation and releases the protonophore 2,4-dinitrophenol locally in predetermined regions in respon

92 One millimolar 2,4-dinitrophenol lowered the ATP in wild type to that in th

93 e protective effect of pretreatment with 2,4-dinitrophenol, measured from increased functional recove

94 For 2,4-dinitrophenol, mitochondria effects were detectable afte

95 tion by 150 microM GS-Succ-BP is provided by dinitrophenol, nitrobenzene, ethacrynic acid, and S-hexy

96 er, serious adverse effects of the uncoupler dinitrophenol occurred when used to increase significant

97 n in residue H19 impaired the binding to 2,4-dinitrophenol only.

98 Out of six possible positional isomers of dinitrophenol, only 2,4-DNP has been used extensively by

99 inhibitors of ATP synthesis (oligomycin, 2,4-dinitrophenol, or 2-deoxyglucose) made them more suscept

100 Strophanthidin inhibits KATP channels in 2,4-dinitrophenol-poisoned heart cells ().

101 Mitochondrial stimulation with 2,4-dinitrophenol reduced both HB magnitude and ELM-RPE thic

102 Addition of the metabolic poisons cyanide or dinitrophenol reduced the active transport of both prote

103 A showed that there was a rapid burst of 2,4-dinitrophenol release.

104 pleted by treatment with sodium azide or 2,4-dinitrophenol; restoration of the original ATP levels oc

105 The uncouplers S13 and dinitrophenol showed that NarK2 was not dependent on the

106 Transport was also inhibited by 2,4-dinitrophenol, suggesting an energy-linked transport mec

107 mitochondrial membrane potential uncoupler, dinitrophenol, supporting a role for mitochondrial regul

108 l assays for the environmental pollutant 2,4-dinitrophenol the alternative devices were 50% more sens

109 rs with very good leaving groups such as 2,4-dinitrophenol, the monoanion of phosphate esters is more

110 Treatment of the FF group with low dose 2,4-dinitrophenol to increase energy expenditure abrogated t

111 fect of four environmental contaminants, 2,4-dinitrophenol, triclosan, n-(1,3-dimethylbutyl)-N'-pheny

112 ation of mitochondria in the presence of 2,4-dinitrophenol uncoupler.

113 ies we have selected a series of 2-alkyl-4,6-dinitrophenols which proved to be very effective noncomp

114 If 2,4-dinitrophenol, which can also be produced by photochemic

115 y reduced binding to both salicylate and 2,4-dinitrophenol, while a mutation in residue H19 impaired