ライフサイエンスコーパス: diphosphonate

1 esence of different functional groups on the diphosphonate.

2 with liposome-encapsulated dichloromethylene diphosphonate.

3 TP analogue guanylyl-(alpha, beta)-methylene-diphosphonate.

4 aphy with technetium 99m ((99m)Tc) methylene diphosphonate.

5 Rhenium-188 (tin) hydroxyethylidine diphosphonate [188Re(Sn)HEDP] is a new radiopharmaceutic

6 AOPCP [adenosine-5'-O-(alpha,beta-methylene)-diphosphonate] (250 microm).

7 ostic performance of (99m)Tc-hydroxyethylene-diphosphonate ((99m)Tc-HDP) planar bone scintigraphy (pB

8 I)-induced improvements in (99m)Tc-methylene diphosphonate ((99m)Tc-MDP) bone scans.

9 tive studies of bone using (99m)Tc-methylene diphosphonate ((99m)Tc-MDP) have a potentially valuable

10 studies of the kinetics of (99m)Tc-methylene diphosphonate ((99m)Tc-MDP) in metastatic and metabolic

11 in patients who underwent (99m)Tc-methylene diphosphonate ((99m)Tc-MDP) whole-body bone scintigraphy

12 99mTechnetium methylene diphosphonate (99mTc MDP) bone scintigraphy is currently

13 liposome-encapsulated drug dichloromethylene diphosphonate, a procedure which depletes macrophages fr

14 Dynamic bone scanning with (99m)Tc-labeled diphosphonates and (18)F-labeled sodium fluoride provide

15 the mechanisms of uptake of (99m)Tc-labeled diphosphonates and (18)F-sodium fluoride and discusses a

16 ase inhibitors: synthesized and FDA-approved diphosphonates and hydroxamates.

17 h technetium pyrophosphate, hydroxymethylene diphosphonate, and 3,3-diphosphono-1,2-propanodicarboxyl

18 polyoxometalate (POM) chemistry, diphosphate/diphosphonate-based POMs represent a more recent area of

19 review we discuss in detail all diphosphate/diphosphonate-based POMs, beginning with early developme

20 )Tc-pertechnetate phantom, (99m)Tc-methylene diphosphonate bone imaging, and measurement of the bindi

21 imaging (CT or MRI, and a (99m)Tc-methylene diphosphonate bone scan) before enrollment.

22 ulfur colloid bone marrow scanning and 99mTc-diphosphonate bone scanning.

23 ploratory analysis, paired (99m)Tc-methylene diphosphonate bone scans ((99m)Tc-BS) were available for

24 nfection, multiphase (99m)Tc-hydroxyethylene diphosphonate bone scans were negative early, but late-p

25 (99m)Tc-hydroxymethylene diphosphonate bone scans were only positive at day 14 in

26 Conventional (99m)Tc-methylene diphosphonate bone scans, (201)Tl tumor imaging, and PET

27 MIBG-nonavid disease, replace technetium-99m diphosphonate bone scintigraphy for osteomedullary metas

28 ), 111In-pentetreotide, and Tc-99m-methylene diphosphonate bone scintigraphy in 30 patients with SDHB

29 maceuticals (99m)technetium dicarboxypropane diphosphonate (bone scintigraphy), (99m)technetium merca

30 olid state for the octabromoacetamide 4a and diphosphonate cavitand 13 by single-crystal X-ray analys

31 ed of their macrophages by dichloromethylene diphosphonate (Cl(2)MDP) injection.

32 linium chloride (GdCl3) or dichloromethylene diphosphonate (Cl2MDP) to assess the effects of macropha

33 n of liposome-encapsulated dichloromethylene diphosphonate (CL2MDP).

34 n of liposome-encapsulated dichloromethylene diphosphonate (Cl2MDP-liposomes or clodronate-liposomes)

35 injection of clodronate- (dichloromethylene diphosphonate) containing liposomes before fully allogen

36 used liposome-encapsulated dichloromethylene diphosphonate determined the role of macrophages.

37 e scintigraphy with technetium 99m methylene diphosphonate (Fig 1B).

38 the GTP analog guanylyl beta,gamma-methylene-diphosphonate (GMP-PCP) (i.e. the presumed signaling-act

39 GTP analog, guanylyl-(alpha,beta)-methylene-diphosphonate (GMPCPP), to examine the structural effect

40 tubules with guanylyl-(alpha,beta)-methylene-diphosphonate (GMPCPP).

41 yzable GTP analogue guanylyl-(a,b)-methylene-diphosphonate (GMPCPP).

42 phate > MANT-guanylyl-(beta,gamma-methylene)-diphosphonate > MANT-guanosine 5'-O-2-(thio)diphosphate.

43 y encapsulated clodronate (dichloromethylene diphosphonate) has previously been found to be a potent

44 Although (18)F-labeled NaF and (99m)Tc-diphosphonate have a similar patient dosimetry, (18)F-fl

45 ty and efficacy of (186)Re-hydroxyethylidene diphosphonate (HEDP) as an adjuvant to external-beam rad

46 , 89Sr-chloride, 186Re-1,1 hydroxyethylidene diphosphonate (HEDP), and 153Sm-ethylene diamine tetrame

47 blood clearance of (99m)Tc-hydroxymethylene-diphosphonate (HMDP) and efficient laboratory throughput

48 icarboxylic acid (DPD), and hydroxymethylene diphosphonate (HMDP) for diagnosis of ATTR-CA, present a

49 hy, bone damages by (99m)Tc-hydroxymethylene diphosphonate imaging, inflammation by (18)F-FDG PET, an

50 nts after a single 600-MBq (99m)Tc-methylene diphosphonate injection.

51 PBS (L-PBS), or liposomal dichloromethylene diphosphonate (L-Cl2MDP), a preparation which leads to s

52 on of liposomes containing dichloromethylene diphosphonate (L-Cl2MDP).

53 ium complexes with multifunctional bipyridyl diphosphonate ligands as well as initial water oxidation

54 c and 75-125 microCi 111In), 99mTc-methylene diphosphonate (MDP) (3-5 mCi) and 67Ga-citrate (500 micr

55 tracers (18)F-fluoride and (99m)Tc-methylene diphosphonate (MDP) are an alternative method to biochem

56 99mTc-methylene diphosphonate (MDP) bone scanning was performed before t

57 tive studies of bone using (99m)Tc-methylene diphosphonate (MDP) reflect bone remodeling.

58 minent soft-tissue uptake of 99mTc-methylene diphosphonate (MDP) within the prostate bed was found af

59 ltriglicine chelator (MAG3), 99mTc-methylene diphosphonate (MDP), 99mTc-hexamethylpropylene amine oxi

60 The potent diphosphonates reduced B. cereus-mediated detachment and

61 included the combination of 99mTc-methylene diphosphonate scintigraphy, CT, or MRI.

62 of (18)F-fluoride PET, compared with (99m)Tc-diphosphonate scintigraphy, support the reconsideration

63 F-fluoride PET is more accurate than (99m)Tc-diphosphonate SPECT for identifying both malignant and b

64 Technetium 99m hydroxymethane diphosphonate SPECT/CT bone tracer uptake was volumetric

65 llar liposome-encapsulated dichloromethylene diphosphonate, the common bile duct was ligated and divi

66 capped with guanylyl (alpha, beta)-methylene diphosphonate-tubulin subunits.

67 scintigraphy using (99m)Tc-labeled methylene diphosphonate was performed, and early-phase knee scans

68 ethyl(2,5-diiodo-1,4-phenylene)bis(methylene)diphosphonate with 10-hexyl-10H-phenothiazine-3-carbalde

69 Diphosphonates with greater chain flexibility (C(12)H(24