ライフサイエンスコーパス: directionally

1 n catch a ride on the cytoskeleton to travel directionally.

2 uronal activity in an opposite manner and bi-directionally.

3 two hexamers that encircle and unwind DNA bi-directionally.

4 hich replication forks emanate and travel bi-directionally.

5 on, which guides the cancer cells to migrate directionally.

6 Notably, RNAPII at enhancers transcribes bi-directionally a novel class of enhancer RNAs (eRNAs) wit

7 ies composition has changed dramatically and directionally across all regions.

8 ion in relative growth rate, appears to vary directionally across geographic gradients.

9 ation in metazoa by communicating signals bi-directionally across the plasma membrane.

10 adhesion receptors that transmit signals bi-directionally across the plasma membranes.

11 e shown that sites of high transcription may directionally affect condensin loop extrusion.

12 We show that polarized HLCs secrete cargo directionally: Albumin, urea, and lipoproteins are secre

13 ing to generation of dynamic subdomains that directionally align a downstream S region with Smu for d

14 ions lead to 68% of walkers taking two steps directionally along a three-foothold track.

15 tein production, in which ribosomes move uni-directionally along an mRNA strand, building amino acid

16 is "zippering," whereby a fusion point moves directionally along an organ rudiment.

17 Drp1 oligomers also translocate directionally along mitochondria.

18 rtificial, linear molecular motors that move directionally along polymeric tracks to transport cargoe

19 In the model, choice variability could be directionally altered through amplification or dampening

20 Serotonin bi-directionally and differentially modulated glutamatergic

21 ws neighboring cells to polarize and migrate directionally and form characteristic chains of cells ca

22 l snapshots of the enzyme cleaving substrate directionally and sequentially from the 5' terminus.

23 ing (macrocycle) is continuously transported directionally around a cyclic molecular track when power

24 Potential applications include directionally asymmetric active devices as well as inten

25 ly, asymmetric die-1 expression controls the directionally asymmetric expression of gustatory recepto

26 lectivity in the retina relies critically on directionally asymmetric GABA release from the dendritic

27 , the rate of movement of CESA particles was directionally asymmetric in mutant lines that exhibited

28 transcription factor die-1 is expressed in a directionally asymmetric manner in the gustatory neuron

29 ovement with a centrifugal bias and, through directionally asymmetric synaptic connections with the d

30 saurid archaeocete skulls are distinctly and directionally asymmetrical.

31 FtsK translocates dsDNA directionally at >5 kb/s, even under strong forces.

32 The FtsK translocase pumps dsDNA directionally at approximately 5 kb/s and facilitates ch

33 zide-polyethylene glycol-dithiol, is used to directionally attach the Fc, or nonbinding region of the

34 ufficient to silence the active VSG gene and directionally attenuate the ES by disruptor of telomeric

35 The nerve growth cone is bi-directionally attracted and repelled by the same cue mol

36 Loss of PINK1 also produced specific, directionally balanced defects in mitochondrial transpor

37 icted to the germinal centre but migrated bi-directionally between dark and light zones.

38 from 4 to 20 bp and, in some cases, leads to directionally biased 3' --> 5' sliding.

39 Here, we describe how such directionally biased data can be used to estimate the ne

40 astrocyte polarization, IF transport becomes directionally biased from the cell center toward the cel

41 ms fibrils through cell contacts and creates directionally biased geometry.

42 unwinding of double-stranded RNA in a 5'-3' directionally biased manner and RNA strand annealing act

43 Further, we found a cell type-specific, directionally biased synaptic plasticity of two major ty

44 ngiogenic sprouting, endothelial "tip cells" directionally branch from existing vessels in response t

45 both primary and cell-line cultures migrated directionally but slowly toward the anode in an electric

46 Gulp1 mediates trogocytosis bi-directionally by dynamic engagement with EphB/ephrinB pr

47 t C-I bond breaking yielded IPh that rotated directionally by three different angles, with the second

48 any cardiovascular and neural responses that directionally challenge blood pressure regulation, reduc

49 generate a focused cDNA library that was bi-directionally cloned into a transitive RNAi vector that

50 an be broken down into two separate streams, directionally coding for elementary motion and figure mo

51 ials designed using this approach are called directionally compliant metamaterials (DCMs) because the

52 P = 9.1 x 10(-3)), while the 1q22 locus was directionally concordant and nominally significant (rs13

53 ed, genome-wide association studies revealed directionally concordant association of rs10749571 with

54 Thus, polarized M2a macrophages drive a directionally concordant expansion of the iTreg-Th17 cel

55 d lymphocyte count, respectively), which was directionally concordant to the observational findings.

56 RNA-sequencing analysis results were directionally concordant with observed and Mendelian ran

57 a) concentration due to rs3777392, which was directionally concordant with the OR observed for a simi

58 rm size in serum due to rs2457564, which was directionally concordant with the OR observed in PROMIS

59 Observational and causal estimates were directionally concordant, except for LDL-C.

60 of pure metals for selected wavelengths, and directionally confined waves similar to those found in o

61 The network model was comprised of two uni-directionally connected neuronal populations of spiking

62 This conclusion is supported by an excess of directionally consistent and nominally significant signa

63 dent PMI cohort (n=15; P<2.30E-4); >85% were directionally consistent and reached nominal significanc

64 ed measures analysis of variance); >90% were directionally consistent and reached nominal significanc

65 total n = 2,579), and the influence remained directionally consistent and significant (p = 0.007).

66 These two loci also yielded directionally consistent associations in a previous meta

67 The meta-analysis showed directionally consistent associations with BMI for all 1

68 59816 (HNF1A), and rs11206510 (PCSK9) showed directionally consistent associations with CHD in the 3

69 All 18 MVPs showed directionally consistent associations with incident and

70 sus quartile 1 of the multi-SNP score showed directionally consistent associations with the hypothesi

71 6 previously established BMI variants showed directionally consistent effect estimates in our GWAS (b

72 Cangrelor resulted in directionally consistent effects on the primary end poin

73 cancer (OR 0.96, 95% CI 0.93 to 0.99) with a directionally consistent estimate for stroke (OR 0.98, 9

74 ems of the Earth's vegetated surface through directionally consistent influence on vegetation greenne

75 nd unobserved factors, this study suggests a directionally consistent linkage between longer door-to-

76 us events (3.9% vs. 4.8%; p = 0.012), with a directionally consistent numerical reduction for procedu

77 grel compared with those of clopidogrel were directionally consistent regardless of aspirin dose, alt

78 The remaining horses shifted from a faster, directionally consistent response with the symmetric bar

79 unting behaviors to rapidly establish highly directionally consistent social relationships.

80 trends with anthropometric traits that were directionally consistent with earlier reports in adults.

81 onfidence interval: 4.56 to 7.49), which was directionally consistent with previous observations.

82 In addition, associations of 14 loci are directionally consistent with previous reports.

83 smission allows subcortical structures to bi-directionally control postsynaptic neurons, thus helping

84 on this coupling, we demonstrate that we can directionally control the lithium distribution by applyi

85 o biases in perceptual choices, which can be directionally controlled through non-invasive brain stim

86 ulticomponent synthetic species that exhibit directionally controlled, stimuli-induced movements of t

87 n (BF) to the lateral habenula (lHb) that bi-directionally controls the valence of aggressive interac

88 ty-related behaviors, indicating that G9a bi-directionally controls these responses.

89 le -880Delta to increase NPY expression were directionally coordinate in vivo (on human traits) and i

90 the substrate-binding cavity in LptFG are bi-directionally coordinated through the rigid-body couplin

91 uctuation deep inside the particle, which is directionally correlated to the polarization of the pump

92 trant excitation patterns and SCRE may be bi-directionally coupled, promoting novel mechanisms of arr

93 ding chemically reactive nanoconstructs with directionally defined valence.

94 The reflectivity of HFL was directionally dependent and increased with eccentricity

95 Other studies have also suggested directionally dependent compressive stiffness suggesting

96 inducible by electric field stimulation with directionally dependent electrical excitation thresholds

97 We attribute this in part to directionally dependent group velocities of optical phon

98 conductance data with modeling, we show that directionally dependent magnitude differences, not tempo

99 rain regulates EMT in a strain magnitude and directionally dependent manner.

100 he direction of vibration and the associated directionally dependent neural response changes with air

101 nsformations in a two-dimensional system are directionally dependent, and confer pronounced plasticit

102 The effect was also directionally dependent, where cyclic strain applied ort

103 amic regimes in which waves either propagate directionally, die out, or spiral indefinitely, and we c

104 ipoles that create an environment favoring a directionally discontinuous channel hydrogen-bonded wate

105 cts in the DG-GCL that were either absent or directionally discordant in bulk hippocampus data.

106 anelles can, therefore, coordinately control directionally distinct cytokine transport.

107 Adult height has shown directionally diverse associations with several age-rela

108 Endothelial cells (ECs) migrate directionally during angiogenesis and wound healing by p

109 igin of replication (oriP) is transcribed bi-directionally during reactivation and that both leftward

110 Although directionally favorable, denosumab was not statistically

111 In the hypha, cytoplasm flows directionally from cell to cell through septal pores.

112 ed eggs without ambient immune reaction, and directionally from granuloma to the central veins, sugge

113 migrate actively in the allantois, and move directionally from the allantois into the proximal epibl

114 Trypanosoma brucei undergoes cytokinesis uni-directionally from the anterior tip of the new flagellum

115 nates from vertically porous structures from directionally grown ice crystals and simultaneously indu

116 eudopodial branching is locally regulated to directionally guide angiogenesis.

117 Acanthamoeba move directionally in a three-dimensional (3D) agar system as

118 genomic lagging strand mismatches occurs bi-directionally in E. coli and that, while all MutS-recogn

119 Acanthamoeba trophozoites move directionally in response to an EF in a two-dimensional

120 at random in the absence of an EF, but move directionally in response to an EF.

121 ection of chemoattractant gradients and move directionally in response to bacterial infections and ti

122 ic breast cancer, and fibrosarcoma) migrated directionally in response to changes in extracellular st

123 nce, little is known about how cells migrate directionally in response to traveling waves.

124 y complementary oligonucleotides are ligated directionally into a zero background BsaI/ccdB-based exp

125 rain registers visual and auditory inputs to directionally localize an interesting environmental feat

126 nylbutyrate versus NaPBA, NH3 -AUC0-24hr was directionally lower on glycerol phenylbutyrate in each s

127 neutral with respect to HDL cholesterol, and directionally lowered the ratio of total to HDL choleste

128 Adaptation enables eukaryotic cells to directionally migrate over a large dynamic range of chem

129 of GMFbeta disrupted the ability of cells to directionally migrate to a gradient of fibronectin (hapt

130 Here, we show that planarian stem cells directionally migrate to amputation sites during regener

131 sion, resulting in a failure of monocytes to directionally migrate toward CXCL12.

132 beta contributes to cellular polarization in directionally migrating cells via effects on Rho GTPase

133 ling signaling events at the leading edge of directionally migrating cells.

134 mmetric front-rear Cdc42-GTP distribution in directionally migrating cells.

135 Synaptic transmission efficacy can be bi-directionally modified through potentiation (long-term p

136 sensitive period during which DA and 5-HT bi-directionally modulate adult aggression.

137 sed using viral-mediated gene transfer to bi-directionally modulate AMPAR activity in the NAc core.

138 enous expression of SNX26 was shown to be bi-directionally modulated by neuronal activity.

139 ms delayed relative to the hippocampus, with directionally modulated grid cells and forward replay ex

140 show that the preferred firing directions of directionally modulated grid cells in rat entorhinal cor

141 We also find that the strength of LE is bi-directionally modulated, in a homeostatic manner, by sni

142 t zebrafish are highly sensitive to drugs bi-directionally modulating brain monoamines, generally par

143 l conceptual framework for understanding how directionally moving prey perceive risk and make antipre

144 wever, current models are not applicable for directionally moving prey.

145 icts how much predation risk is perceived by directionally moving prey.

146 bA, and sucralose, whereas weight change was directionally negative and lower for sucralose compared

147 paration and movement that would allow for a directionally non-specific component of preparatory visu

148 e alphav integrin to migrate efficiently and directionally on CAF-derived matrices.

149 e demonstrate that CV membranes also move bi-directionally on microtubules between the cortex and the

150 of secretory vesicle fusion and re-assembled directionally on vesicle membranes.

151 omosomes can exert focal, nonoverlapping and directionally opposed influences on CT asymmetry within

152 Under conditions of ischaemia, there is a directionally opposite autonomic response with a signifi

153 ditions of myocardial ischaemia, there was a directionally opposite cardiac autonomic response with a

154 e loci show sex-divergent effects, including directionally opposite effects between sexes at the SIM1

155 mimic or antagomir oligonucleotides yielded directionally opposite effects on contraction rate in pr

156 ate 2 populations of single units exhibiting directionally opposite firing when atrial pressure is pe

157 al acoustic changes and/or changes that were directionally opposite to treatment responders.

158 he patients the change in PAWP and E/e' were directionally opposite.

159 ariance determines if phenotypes will evolve directionally or whether they reside at an evolutionary

160 These antibodies were directionally orientated as receptors by thin film depos

161 y, divisions and migration were primarily bi-directionally oriented along the ghost fiber longitudina

162 RNA polymerase transcription complexes co-directionally oriented with the replication fork were tr

163 which serve as hydrogen-bond acceptor sites, directionally orienting the hydrogen atoms of the interf

164 n order to exert traction forces on and move directionally over the dermis.

165 s the paired genes into three categories (co-directionally-paired genes or CDPGs, convergently-paired

166 sotropic wetting on one-dimensional (1D) and directionally patterned surfaces, as well as the technic

167 ne secretion of exosomes powerfully promotes directionally persistent and effective cell motility by

168 exosomes from late endosomes is required for directionally persistent and efficient in vivo movement

169 Our results suggest that vinculin promotes directionally persistent cell migration and tension-depe

170 Further, directionally persistent cell migration was inhibited su

171 agamma effectors in the pathways controlling directionally persistent motility.

172 to stabilize forward-directed protrusion and directionally persistent movement.

173 All RINs then transition to a less directionally persistent multipolar phase of migration.

174 tribution of step lengths, 2) motion that is directionally persistent over short time scales, and 3)

175 Later in infection, motility is faster and directionally persistent, resulting in long, straight ac

176 nanocrawler, which reversibly moves along a directionally polar complementary road controlled by aff

177 leads to a chemically ratcheted walk along a directionally polar DNA track.

178 either an N- or a C-terminal alkylamine for directionally preferred peptide immobilization.

179 sence of ClpP ClpA translocates polypeptides directionally, processively and in discrete steps simila

180 other modulating this binding, can transform directionally random DNA fluctuations into directed moti

181 Thus, Egr1 and REST can bi-directionally regulate Ca(V)3.2 promoter activity and mR

182 NR1 phosphorylation was bi-directionally regulated after DFP in striatum versus hip

183 ing the phase of hormone repression, of a bi-directionally regulated hormone target gene, and provide

184 he only phage integrase system available for directionally regulated site-specific DNA integration in

185 We found that synaptic activity bi-directionally regulates neuronal Tet3 expression.

186 n is confined to cytolytic granules that are directionally released following target cell recognition

187 fects and replicates in pHAE cultures and is directionally released on the apical, but not basolatera

188 e association of rs11014566 with BMI did not directionally replicate when assessed in other ethnic gr

189 ppocampus provide key nodes sufficient to bi-directionally reprogram both the neural and behavioral e

190 inar cells, which function to synthesize and directionally secrete digestive enzymes into a central l

191 ess responses, and most were associated with directionally selected traits, which may have been an ad

192 uption of viral compartment is transient and directionally selected.

193 een thought to contain two distinct types of directionally selective (DS) ganglion cell: a bistratifi

194 SACs exhibit opposite polarity, directionally selective (DS) light responses, depolarizi

195 (BT), brisk-sustained (BS), local edge (LE), directionally selective (DS)], comparing small vs. large

196 We then used this strategy to create directionally selective ablations of three distinct path

197 Drosophila, the T4 cells of the medulla are directionally selective and necessary for ON motion beha

198 ng, we found that these neuron types are not directionally selective and that selectivity arises in t

199 sectors of the starburst dendritic field are directionally selective by virtue of a mutually inhibito

200 In visual areas V1 and MT, some directionally selective cells are also tuned for the sec

201 To address this issue, we recorded from directionally selective cells in visual area MT of monke

202 The ON-OFF directionally selective cells of the retina respond pref

203 r pathways, whose selective damage may cause directionally selective eye movement disorders.

204 These results reveal that directionally selective fMRI patterns in motor system ar

205 Directionally selective fMRI patterns in PPC, however, w

206 tion, thereby demonstrating the existence of directionally selective fMRI patterns within each stage

207 ic arm also receives local inhibitory inputs directionally selective for inward motion opposing the e

208 in the population of superior coding ON-OFF directionally selective ganglion cells (DSGCs) genetical

209 l and global forms of inhibition controlling directionally selective ganglion cells (DSGCs) in the ma

210 e, we present evidence for a third strategy: directionally selective ganglion cells (DSGCs) in the mo

211 lay a predictable, causal role in-generating directionally selective hippocampal responses.

212 neurons in area MT, which depend in turn on directionally selective inputs from area V1.

213 ry systematically with stimulus direction in directionally selective middle temporal (MT) neurons, le

214 t of flight to modulate the response gain of directionally selective motion-detecting neurons in Dros

215 tivation of either octopaminergic neurons or directionally selective motion-detecting neurons that ex

216 levels and the temporal tuning of the first directionally selective neuron in the ON motion pathway

217 he first robust evidence for the presence of directionally selective neuronal populations in human pr

218 odulation acts directly on the inputs to the directionally selective neurons and supports efficient n

219 to record and manipulate all major inputs to directionally selective neurons in Drosophila.

220 ns in their respective pathways to extract a directionally selective response from their non-selectiv

221 oubt on earlier assumptions that PI provides directionally selective signals to MT and instead sugges

222 In the fly visual system, directionally selective small-field neurons called T4 an

223 es a new group of DS neurons that are highly directionally selective to moving objects.

224 Most of the recorded units were directionally selective.

225 indicating that the presynaptic neurons were directionally selective.

226 xcitatory input to the LGMD is intrinsically directionally selective.

227 e modality specific (odor > tone attention), directionally sensitive (forward > backward connections)

228 hat the observed head-orientation coding and directionally sensitive cells are essential components o

229 racellular signal but responds by initiating directionally sensitive migration to a persistent signal

230 s are ATP-dependent machines responsible for directionally shifting nucleosomes along DNA.

231 Directionally similar effects were observed for the abov

232 anolazine in patients with BNP >80 pg/ml was directionally similar for recurrent ischemia (HR: 0.78;

233 oaches showed good concurrent validity, with directionally similar responses between: (a) Doppler-der

234 This change is directionally similar to the androgen-induced lipolytic

235 onses measured by many of the techniques are directionally similar, in others they are divergent.

236 Directionally, similar results were also seen with Ad-PL

237 stals, but rather arrays of simple particles directionally sintered into porous sheets.

238 he first time, fine and equiaxed crystals in directionally solidified Al-10Si braze alloy.

239 a hypereutectic Al-40 wt.%Cu alloy has been directionally solidified under various axial magnetic fi

240 ppm (x = 0.8, as-cast) and 188 ppm (x = 0.8, directionally solidified), accompanying with the increas

241 e movements, and that this interaction has a directionally specific component.

242 unwinding duplex DNA in an ATP-dependent and directionally specific manner and play essential roles i

243 ses in a systematic, temporally precise, and directionally specific manner to generate depth-sign sel

244 gain of responses of neurons in area MT in a directionally specific manner to generate selectivity fo

245 Here, we used a novel directionally specific viral ablation approach to invest

246 deposited on the inflamed vasculature and to directionally spread, to polarize and to govern haptotac

247 involved in initially polarizing cells, Sdf1 directionally stabilizes cell protrusions promoted by ce

248 proteolytic component ClpP, processively and directionally steps along the polypeptide backbone with

249 The compliant radiofrequency balloon can directionally tailor energy delivery for efficient, effe

250 Previously, we showed that RepD recruits directionally the PcrA helicase to the pC221 oriD, remai

251 both neuronal populations were connected bi-directionally, the relative alpha phase determined the d

252 pbeta) family use RanGTP to transport cargos directionally through the nuclear pore complex (NPC).

253 temperature and that composition is changing directionally through time, potentially in response to c

254 the roof plate boundary organiser signals bi-directionally to acutely coordinate the development of a

255 ns, the growth cones, navigate by responding directionally to guidance cues that pattern the embryoni

256 ots possess the ability to sense and respond directionally to other chemical and physical stimuli, se

257 aging, we show human primary T cells migrate directionally to the cathode in low strength (50/150 mV/

258 st epithelial cells secrete nascent proteins directionally toward a single lumen, the hepatocyte secr

259 We find that body size evolved directionally toward phyletic giantism an order of magni

260 CD4 single positive (SP) thymocytes migrated directionally toward the medulla, where they accumulated

261 for neuronal guidance, in which axons extend directionally toward their target tissues.

262 ere a linear assembly of tumor cells migrate directionally towards blood vessels on fibronectin-colla

263 ex formation initiate at the PAM and proceed directionally towards the distal end of the target seque

264 Hexanucleotide repeat expansion in the bi-directionally transcribed C9orf72 gene is the most frequ

265 n enhancers or super-enhancers, including bi-directionally transcribed enhancers, which are often res

266 We investigated the bi-directionally transcribed Na/phosphate cotransporter gen

267 Recent studies have identified bi-directionally transcribed RNAs emanating from these enha

268 we showed that the entire D4Z4 repeat is bi-directionally transcribed with the generation of small s

269 hat the heme-bound form of IsdX1 rapidly and directionally transfers heme to IsdC, a NEAT protein cov

270 H) protein harboring a NEAT domain binds and directionally transfers heme to the Isd system via the c

271 cells, predicting that Usher proteins may be directionally transported as complexes in hair cells and

272 sisting of motor and regulatory proteins are directionally transported down the axis of a cell at con

273 ation ratchet in which the macrocycle can be directionally transported in either direction along an a

274 tiary amine gradient, anionic molecules were directionally transported up to several millimeters.

275 , in recent years, highlighted that fluid is directionally transported within the central nervous sys

276 redox-mediated, disulfide-exchange reaction directionally transports the bipedal molecules away from

277 uronal activity in the frontal eye field was directionally tuned before both primary and secondary sa

278 on result from shifts in the balance between directionally tuned excitation and inhibition mediated b

279 how direction selectivity is implemented by directionally tuned excitatory and inhibitory mechanisms

280 ction-selective ganglion cell circuit, where directionally tuned inhibition is known to shape non-dir

281 r (NMDAR) conductances in DSGC dendrites and directionally tuned inhibition provided by the upstream

282 We found that, even without directionally tuned inhibition, direction selectivity ca

283 The inhibitory inputs onto DSGCs are directionally tuned to the antipreferred (null) directio

284 ion at the first harmonic frequency and were directionally tuned.

285 ticipant result in DPPS expansion, an effect directionally-tuned towards the source of the arrows.

286 t of ~60 nm above that membrane, composed of directionally unaligned, densely packed actin filaments,

287 the nucleosome can unwrap asymmetrically and directionally under force.

288 ermines whether the macrocyclic products are directionally uniform or scrambled.

289 nucleus prepositus caused HD cells to become directionally unstable under dark conditions without aff

290 y composed of two distinct components: (1) a directionally untuned component, which appears to play t

291 B-1 localize within TNTs, are transported bi-directionally via TNTs and facilitate TNT formation in P

292 eading population of cells that moves highly directionally, while cells behind this group are undirec

293 g revealed that tracheal sprouts invade IFMs directionally with growth-cone-like structures at branch

294 to efficiently capture and push microtubules directionally with leading plus ends.

295 visual thalamus communicates broadly and bi-directionally with primary and extrastriate cortical are

296 e invasion in gradient hydrogels occurred bi-directionally with sprout alignment observed in the dire

297 has a class 17 myosin motor domain, moves bi-directionally, with myosin-5 and kinesin-1 cooperating i

298 nt to transcription initiation site slide bi-directionally, with the third nucleosome remaining at th

299 that MAPs with asymmetric friction can move directionally within actively moving microtubule pairs t

300 , including pseudorabies virus (PRV), spread directionally within the nervous systems of their mammal