ライフサイエンスコーパス: disaggregate

1 uals navigate groups and how groups form and disaggregate.

2 In both cases, the released AgLDL was disaggregated.

3 figures for persons above age 84 years were disaggregated.

4 effects of individual measures could not be disaggregated.

5 are protein complexes that help to fold and disaggregate a cell's proteins.

6 To disaggregate a decade of national CVD mortality data for

7 They concluded that NDGA could disaggregate Abeta fibrils into aggregates that were lar

8 Although NDGA failed to disaggregate Abeta protofibrils, it did inhibit direct p

9 ibrils but accelerate aggregation of freshly disaggregated Abeta.

10 a suggest that low dose curcumin effectively disaggregates Abeta as well as prevents fibril and oligo

11 ique ability to hinder the formation of, and disaggregate, Abeta assemblies in vitro (EM experiments)

12 hosphates or oligomers of acidic amino acids disaggregate actin bundles into single filaments.

13 sp70-binding site elicits the Hsp104 protein disaggregating activity that now depends on Strep-Tactin

14 es cerevisiae prions requires Hsp104 protein disaggregating activity, overproducing Hsp104 "cures" ce

15 which is required to unleash Hsp104 protein disaggregating activity.

16 h-resolution immunohistochemical analysis of disaggregated adult canine sinus node preparations.

17 xcel-based static cohort model with a finely disaggregated age structure.

18 e 8- and 12-14-kDa species were treated with disaggregating agents.

19 d health (MNCH), but no analysis to date has disaggregated aid for newborns.

20 this study was to use statistical methods to disaggregate all publicly funded health expenditure by d

21 molecular chaperones in both preventing and disaggregating alpha-synuclein oligomers and fibrils, wi

22 To disaggregate amyloid, several subunits cooperatively eng

23 approach to inhibiting amyloid formation and disaggregating amyloid fibrils.

24 In addition to disaggregating anaemia prevalence (separately in men and

25 he findings also suggest, however, that more disaggregated analyses are necessary, since beneficial e

26 Disaggregated analyses at the individual surgeon level r

27 our time-series cross-sectional dataset for disaggregated analyses.

28 of experimental design, and (5) conduct sex-disaggregated analysis and reporting.

29 In this study, we conducted a comprehensive disaggregated analysis of MetS prevalence across diverse

30 potential masked health disparities through disaggregated analysis.

31 stems with ClpB and Hsp104, respectively, to disaggregate and reactivate aggregated proteins and amyl

32 cooperate with the Hsp70 chaperone system to disaggregate and reactivate heat-denatured aggregated pr

33 ration of the DnaK/Hsp70 chaperone system to disaggregate and reactivate insoluble aggregated protein

34 Macrophages can disaggregate and release sequestered aggregated LDL by a

35 mmunity composition as communities gradually disaggregate and the least tolerant species are no longe

36 gomers into fibrils, but is inactive against disaggregated and fibrillar Abeta.

37 n occurs in embryonic ectoderm that has been disaggregated and reaggregated.

38 Ovarian serous adenocarcinomas were disaggregated and subjected to growth conditions selecti

39 (Uncaria tomentosa) ingredient for reducing /disaggregating and inhibiting AB 1-42 fibrils and tau pr

40 e workers in which migrant data could not be disaggregated, and studies that did not explicitly repor

41 y help explain the known ability of soluble, disaggregated antigen to induce a state of B cell tolera

42 e treated with Leuko-Rapa, flow cytometry of disaggregated aortic tissue revealed fewer proliferating

43 onflict relationships using a geographically disaggregated approach.

44 he parental chromosomes in single cells from disaggregated arrested embryos and excluded cells from b

45 ly attached to the surface and progressively disaggregate as shear rate exceeds 6000 s(-1).

46 role of social determinants of health across disaggregated Asian American ethnic groups.

47 racial and ethnic groups, particularly among disaggregated Asian and Hispanic subgroups.

48 tes in immature starfish oocytes and becomes disaggregated at the time of its activation during matur

49 Enzymatically disaggregated atrial and ventricular mouse myocytes were

50 n as a dermal analog was seeded with freshly disaggregated autologous keratinocytes and applied to fu

51 s age groups, highlighting the importance of disaggregating BC incidence rates into age groups better

52 e these changes are most likely to matter by disaggregating biases by population size, degree of urba

53 enough to keep the whole proteome folded and disaggregated but no higher).

54 rillion of personal health care spending was disaggregated by 155 conditions, age and sex group, and

55 ggregates in the ER lumen and can be rapidly disaggregated by addition of a ligand to generate a near

56 Genome-wide association disaggregated by admixture mapping reveals novel COVID-1

57 e expectancy gains and deficits were further disaggregated by age and cause of death with demographic

58 countries to provide case and fatality data disaggregated by age and sex to improve real-time target

59 3 produced estimates for 292 causes of death disaggregated by age-sex-location-year in 204 countries

60 ion, existing fibrils of alpha-synuclein are disaggregated by baicalein.

61 crete species on SEC, and they are completed disaggregated by boiling in 1% SDS.

62 Surface air temperature trends are disaggregated by boreal cold (November-April) versus war

63 in the United States from 1996 through 2013, disaggregated by condition, age and sex group, and type

64 Estimates were disaggregated by COVID-19 versus non-COVID causes of dea

65 like fragments by their portals and could be disaggregated by detergents, supporting a role for membr

66 ian or Pacific Islander group with subgroups disaggregated by ethnicity and by monoethnic or monoraci

67 shed anthropogenic emissions inventories are disaggregated by gas, sector, country, or final energy f

68 By analyzing migration flows disaggregated by gender, the study compares the performa

69 Many did not present data disaggregated by gender.

70 We estimated deworming coverage disaggregated by geography, wealth quintile, and sex, an

71 Multivariable Poisson regression models, disaggregated by key population, were constructed to est

72 e of measures and monitor developmental data disaggregated by language status to stimulate efforts to

73 (3) How is total health spending disaggregated by NCDs across age and by sex?

74 Fulfillment trends were disaggregated by prescriber modality and state policy en

75 coronavirus disease 2019 (COVID-19) patients disaggregated by race/ethnicity remains limited.

76 eru, information on mortality rates from GIB disaggregated by region and sex is limited.

77 in this population, and an increase in data disaggregated by risk groups.

78 d under-five (under age 5 y) mortality rates disaggregated by sex is complicated by problems with dat

79 Health data disaggregated by sex is vital for identifying the distri

80 related with SUVmax for the whole cohort and disaggregated by sex.

81 These multimers could be disaggregated by sulfhydryl reagents and by dimethylmale

82 l sample bacteria counts for source and HSW, disaggregated by supply type.

83 This pattern was robust when the scores were disaggregated by the 4 conditions (P<.001 to <.05), by c

84 ionships to estimate future health spending, disaggregated by the source of those funds, to identify

85 Analyses were disaggregated by time periods and patients' characterist

86 When fish was disaggregated by types, BDE-99 and summation operatorPBD

87 Data disaggregated by US state were extracted from public dat

88 Disaggregating by specific crops and sectors, we find th

89 Ebola household secondary attack rate (SAR), disaggregating by type of exposure (direct contact, no d

90 nt activation in adult skin or assemble from disaggregated cells, they are polyclonal in origin.

91 skin was also measured by direct analysis of disaggregated cells.

92 We find that overproduction of the disaggregating chaperone, Hsp104, increases the frequenc

93 il middle subdomain, the signature domain of disaggregating chaperones.

94 The disaggregated chemokines retained their human immunodefi

95 owever, such data on children are scarce and disaggregated clinical data across all ages in this epid

96 Subsequent analysis on primary disaggregated colorectal tumors show that the antibody r

97 aggregates initially were very unstable and disaggregated completely within 2 min.

98 0) protofibrils prepared in buffer alone and disaggregated completely within 3 min on dilution.

99 We disaggregated costs according to intervention characteri

100 igh-burden countries and trend analyses with disaggregated data for age and sex are rare but indicate

101 service and underscore the importance of sex-disaggregated data in understanding health inequities an

102 We disaggregated data into three sectors, artisanal (unpowe

103 gender policies and regulators are requiring disaggregated data, actions which impact research design

104 By examining disaggregated data, this study found persistent inequiti

105 ures should be reported together, along with disaggregated data; inequality should be reported alongs

106 ystems approach to the problems; accessible, disaggregated data; new approaches to service provision

107 Disaggregating data along a health pathway, i.e., the me

108 r analysis on renters in the private sector, disaggregating data between an intervention group receiv

109 mediate cell recovery after severe stress by disaggregating denatured proteins through a poorly under

110 not be grouped into distinct classes, and we disaggregate differentially expressed genes according to

111 ss-sectional, ecological study, we extracted disaggregated disease burden data from the Global Health

112 Hsp104, a hexameric AAA+ ATPase from yeast, disaggregates diverse structures, including stress-induc

113 In the presence of the disaggregating drug these proteins transit the secretory

114 Latent class analysis was applied to 14 disaggregated DSM-III-R symptoms for major depression re

115 g individual caribou that were aggregated or disaggregated during calving and varied in their annual

116 model suggests the compounds may exert their disaggregating effects on the N terminus of the fibril c

117 ique is further enhanced to calculate highly disaggregated emission factors for a wide range of vehic

118 ree Hb is an endotoxin-binding protein which disaggregates endotoxin and subsequently increases the b

119 CURE provides spatially disaggregated environmental intelligence at a local scal

120 We first developed a highly disaggregated environmentally extended mixed unit input

121 We discuss available sex-disaggregated epidemiological data from the COVID-19 pan

122 e in comparison to paclitaxel; however, they disaggregated ES-2 tumor spheroids, whereas single drugs

123 ka2 is an automated algorithm that generates disaggregated estimates of aid for reproductive health,

124 severe forms of tuberculosis disease, no age-disaggregated estimates of paediatric tuberculosis morta

125 This report underscores the importance of disaggregating ethnic/racial groups and depression thera

126 Moreover, EGCG is not able to disaggregate existing amyloid fibrils at a phospholipid

127 ilized, but the rate of dephosphorylation of disaggregated FcepsilonRI was comparable in intact and p

128 were as active against aggregated as against disaggregated FcepsilonRI.

129 aggregation (IC(50) = 0.8 microM) as well as disaggregated fibrillar Abeta40 (IC(50) = 1 microM), ind

130 Platelets lacking PI3Kgamma disaggregated following low-dose adenosine diphosphate (

131 multiple levels of breakdown and used it to disaggregate food mixtures into their ingredients so tha

132 Findings were disaggregated for participants with and without persiste

133 therapeutic uses of chemokines implying that disaggregated forms may be necessary for safe clinical i

134 Aggregated and disaggregated forms of hMIP-1alpha, hMIP-1beta, and RANT

135 evelop spatiotemporally resolved, sectorally disaggregated fossil fuel CO(2) (FFCO(2)) emission data

136 ontaining aggregates, PrP(res) was partially disaggregated, fractionated by size and analysed by ligh

137 the associated soil moisture on a spatially disaggregated framework.

138 cipants reported the severity of 12 symptoms disaggregated from the nine DSM-III-R criteria for major

139 Single-cell disaggregates from adult C57BL/6 mice were prepared from

140 angerhans cells-like dendritic cells and KC, disaggregated FSDDC were cocultured with primary murine

141 By disaggregating gains in child health in Bangladesh over

142 In sex-disaggregated genome-wide association studies for COVID-

143 a unique, biologically consistent, spatially disaggregated global livestock dataset containing inform

144 imated their models after adding measures of disaggregated Graduate Record Examination scores by fiel

145 ces of data and 2.9 billion patient records, disaggregated health care spending in the United States

146 Using observed flowering dates and disaggregating heat-stress impacts, both pre- and postfl

147 pite effective kinase inhibition, H2O2 still disaggregated HSP27, but not alphaB crystallin.

148 Injection of disaggregated human GW39 colon cancer cells into the ham

149 lthy individuals but readily identifiable in disaggregated human splenocytes and increased in both ca

150 ll set of molecules which have been shown to disaggregate IAPP amyloid fibrils.

151 of IAPP amyloid formation and compounds that disaggregate IAPP amyloid.

152 unseeded amyloid fibril formation as well as disaggregates IAPP amyloid.

153 arming: land management categories should be disaggregated in emissions reporting and targets to bett

154 Conversely, nano-CeO(2) and nano-Mn(3)O(4) disaggregated in RE with time, decreasing from 289 5 nm

155 LPS associated with LBP and BPI(N)-LBP(C) is disaggregated in the presence of CD14.

156 to global markets, we highlight the need for disaggregated indicators that reflect the diversity of h

157 The remaining disaggregated insulin, excluding the toxic reactive spec

158 all biodiversity metrics are challenging to disaggregate into animal-mediated ecosystem functions su

159 re extremely rare due to their propensity to disaggregate into their tetrylene monomers R(2) E.

160 155 conditions (including cancer, which was disaggregated into 29 conditions).

161 Twelve-month NCS/DSM-III-R disorders were disaggregated into 3.2% severe, 3.2% serious, 8.7% moder

162 f social fears assessed in the survey can be disaggregated into a class characterized largely by spea

163 chedule to calculate payments, with services disaggregated into clinically meaningful categories.

164 illance data, we show that ILI signal can be disaggregated into distinct viral components.

165 mbined immunodeficient (NOD/SCID) mice, were disaggregated into single-cell suspensions and analyzed

166 raphic sleep correlates of depression can be disaggregated into state-independent and partially rever

167 closely to the fraction of beta-cells in the disaggregated islet cell preparation.

168 Single cells from disaggregated islets were individually isolated in a mic

169 by fluorescence-activated cell sorting from disaggregated late blastula- and gastrula-stage sea urch

170 The released disaggregated LDL particles were competent to stimulate

171 -crystallin chaperone protein to dissolve or disaggregate lenticular opacities.

172 Here, we propose an approach to disaggregate low-frequency passive L-band microwave data

173 se mutations decrease the ability of LptE to disaggregate LPS.

174 GrK disaggregates LPS from micelles and augments LPS-CD14 co

175 LPS transfer protein in the OM translocon by disaggregating LPS during transport to allow for its ins

176 ned cells were detected by flow cytometry in disaggregated lymph node cells from 11 subjects and cons

177 CCR5 was analyzed by flow cytometry in disaggregated lymph node cells from untreated HIV-1-infe

178 r delaying amyloid fibril nucleation and for disaggregating mature apolipoprotein C-II fibrils.

179 4,000 climate protests, we created a highly disaggregated measure of protest participation.

180 Use of TPM to disaggregate melanoma exosomes post electroporation was

181 n methods suffer from the scarcity of gender disaggregated migration data.

182 from yeast, have been engineered to robustly disaggregate misfolded proteins connected with ALS (e.g.

183 erpreted with respect to the target rule for disaggregating misfolded proteins.

184 ins, PrP(Sc) derived from the 87V strain was disaggregated more rapidly than that derived from 22L.

185 RH receptor (CRHR) and c-kit double-positive disaggregated mouse skin mast cells.

186 In conclusion, widely used methodologies to disaggregate Mtb may introduce experimental artifacts in

187 rotein Rhes, which is known to sumoylate and disaggregate mtHtt.

188 ClpB is a member of a protein-disaggregating multi-chaperone system in Escherichia col

189 om Escherichia coli is a member of a protein-disaggregating multi-chaperone system that also includes

190 this modification, without phosphorylation, disaggregates multimeric HSP27.

191 ce of using population as a linear proxy for disaggregating national- or state-scale emissions.

192 To test the hypothesis that HSV disaggregates ND10 structures and disperses PML to precl

193 in an in vivo skin reconstitution assay with disaggregated neonatal dermal cells.

194 43 occurs in the adult heart or is unique to disaggregated neonatal myocytes that are actively reesta

195 s of action potential parameters in cultured disaggregated neonatal ventricular myocytes from Cx43 -/

196 Rs operate in the cytoplasm to chaperone and disaggregate NLS-bearing clients.

197 We disaggregated observed CVD mortality in 1990 and 2013 in

198 asis: the recognition, sorting, folding, and disaggregating of the cell's many different proteins.

199 k variant of sTREM2 is less able to bind and disaggregate oligomeric AB but rather promotes AB protof

200 of cellular stress pathways to help refold, disaggregate or degrade the mutant disease proteins.

201 Disaggregated or fibrillar forms of Abeta42 showed much

202 through which the inhibitor peptides bind to disaggregated or otherwise free Abeta16-22 peptides in s

203 d shear flow, pre-existing clusters of cells disaggregate, orientate with flow, and deform.

204 CyP40 was also able to interact with and disaggregate other aggregating proteins that contain pro

205 Chaperones of the Hsp70 family can further disaggregate otherwise irreversible aggregate species su

206 Employing disaggregated panel data at the grid level, we find that

207 ts the risk for an outcome and is applied to disaggregate patients within RCTs to define risk-based v

208 ther Abeta conformations, such as fibrils or disaggregated peptide; it also differentiates between di

209 Disaggregated perinuclear relocalization of germ plasm d

210 mate the prevalence and severity of selected disaggregated physical and biological oral conditions am

211 ore, proteolysis of VWF appears promising to disaggregate platelet-rich thrombi and restore vessel pa

212 aperones are known to stabilize, unfold, and disaggregate polypeptides away from the ribosome.

213 wball sampling, and the sample represented a disaggregated population of Asian Americans and all 4 me

214 akers in many low-resource settings lack the disaggregated poverty data required to make effective ge

215 1 (NUCB1) prevent hIAPP fibril formation and disaggregate preexisting hIAPP fibrils.

216 ability to prevent formation/aggregation and disaggregate preformed Abeta fibrils (1-42 and 1-40) and

217 event amyloid formation by IAPP and does not disaggregate preformed IAPP amyloid fibrils;, instead, i

218 ), completely inhibited fibril formation and disaggregated preformed fibrils, whereas other polyQ-spe

219 Further, HTRA1 disaggregates preformed alpha-syn fibrils, rendering the

220 bitor of in vitro IAPP amyloid formation and disaggregates preformed amyloid fibrils derived from IAP

221 wever, past research evidences difficulty in disaggregating prenatal environmental influences from ge

222 ating transcriptomic and proteomic data from disaggregated primary human keratinocytes held in suspen

223 erone system and ClpB/Hsp104 collaboratively disaggregate protein aggregates and reactivate inactive

224 utants were also defective in the ability to disaggregate protein aggregates with ClpB, DnaJ and GrpE

225 Whereas the ability to disaggregate proteins is dependent on the Hsp104 M-domai

226 slocation, but precisely how Hsp104 hexamers disaggregate proteins remains incompletely understood.

227 The mechanism by which Hsp104 disaggregates proteins is not completely understood but

228 vitro affinity for PrP or had the ability to disaggregate PrP(Sc) in infected brain homogenates.

229 stimulate converting activity and partially disaggregate PrP(Sc), both scrapie infectivity and conve

230 The sex ratio estimates were used to disaggregate published series of both-sexes mortality ra

231 We observe that the disaggregated Q10 (DQ10) solutions adopt PPII-like and 2

232 Disaggregated quality-adjusted life years (reporting sep

233 s node, isolated canine Purkinje fibers, and disaggregated rabbit sinus node myocytes.

234 ngly, high concentrations of RANTES, but not disaggregated RANTES variants, enhanced infection of cel

235 that percepta has the most potent ability to disaggregate/reduce AB 1-42 fibrils and tau protein pair

236 nto large oligomers O(L), which subsequently disaggregated reversibly into small oligomers O(S) at pH

237 We found that the known disaggregating role of Met-35 sulfoxide could be capital

238 Disaggregated safety data were not available at the time

239 lpha3beta1 integrin suppresses the growth of disaggregated SCLC cells.

240 Analysis of disaggregated sinus node preparations revealed three pop

241 ng stations to each respondent's SWB at both disaggregated spatial and temporal levels.

242 ment, donor, and out-of-pocket spending, and disaggregated spending for vaccines and delivery costs,

243 chaperone that has the remarkable ability to disaggregate stress-damaged proteins.

244 mechanisms of intersubunit collaboration to disaggregate stress-induced aggregates versus amyloid.

245 that Hsp104 hexamers deploy more subunits to disaggregate Sup35 prion strains with more stable "cross

246 We used wavelet methods to disaggregate synchronous fluctuations by timescale and d

247 ppressed by an HSF1-dependent mechanism that disaggregates TDP-43.

248 this study is to emphasize the importance of disaggregating temperature exposures within growing seas

249 elements of the heat-shock chaperone pathway disaggregate the A-bodies.

250 egrades LDL apolipoprotein B sufficiently to disaggregate the aggregated LDL, releasing it from the m

251 General population survey data are used to disaggregate the associations of substance use disorders

252 ion, investigators rely on varied methods to disaggregate the bacteria for these studies.

253 We were able to disaggregate the data by country and vaccine type, and m

254 Our aim was to disaggregate the effects of cash transfer from those of

255 te, county, local, and point source level to disaggregate the inventory and allocate the spatial and

256 oxidative protein Swollenin, can open up and disaggregate the less-ordered regions of lignocellulosic

257 When applied to Exon arrays, it can further disaggregate the signal between alternative transcripts

258 IV and antiretroviral treatment estimates to disaggregate the WHO paediatric tuberculosis incidence e

259 a surgical cohort of patients with NSCLC and disaggregated the findings by sex.

260 We disaggregated the hypertension care cascade by age, sex,

261 d RML prions to branched polyamines in vitro disaggregated the prion rods, reduced the beta-sheet con

262 Our model disaggregates the costs of regional pollution and NRP ex

263 Herpes simplex virus (HSV) 1 disaggregates the nuclear domain 10 (ND10) nuclear struc

264 h an HSF1-dependent chaperone mechanism that disaggregates the protein.

265 ping Bayesian Gene eXpression (MMBGX), which disaggregates the signal at 'multi-match' probes.

266 craping the biofilm from the coupon surface, disaggregating the clumps, then diluting and plating for

267 Disaggregating the concept of the 'GMO' is a necessary c

268 Disaggregating the cross-section of ages by year of birt

269 Disaggregating the data into the JMP sanitation ladder,

270 y after occlusive thrombosis by specifically disaggregating the external layer of occlusive thrombi,

271 Since the tissue is not disaggregated, the location of cells is readily determin

272 The study addresses these issues, disaggregating their overlapping effects.

273 We disaggregated these stages by state, rural-urban residen

274 Disaggregating these global findings shows that the rich

275 eceptor occupancy in the local coronary bed, disaggregate thrombus in the epicardial artery and micro

276 ed because of lack of large-scale, spatially disaggregated time-series data on antibiotic use and res

277 dization assay on immune cells isolated from disaggregated tissue.

278 the assembly process is reversed and fibrils disaggregate to form stable oligomers, hence acting as a

279 Results are disaggregated to characterize the relationship between g

280 Estimates temporally disaggregated to consider water scarcity for at least on

281 tic projections of daily future weather were disaggregated to hourly and used to drive empirically ca

282 regated to 60 +/- 10 nm in the stomach, then disaggregated to individual nanoparticles (26 +/- 2 nm)

283 Pluripotent stem cells are disaggregated to single cells and then differentiated in

284 ow that this chaperone system preferentially disaggregates toxic oligomers and short fibrils, while i

285 The importance of using the most disaggregated trade data set available when resolving us

286 Health Plan Claims Database, we studied and disaggregated trends in use and in insurance and out-of-

287 s, the current study used multicolor FACS of disaggregated tumor to systematically characterize the f

288 e in flow-sorted tumor and immune cells from disaggregated tumors identified CD11b(+)/CD45(+) macroph

289 Flow cytometry of disaggregated tumors posttreatment with either liposomes

290 n ex vivo enrichment process against freshly disaggregated tumors to purge the repertoire, in combina

291 These can be disaggregated using purified cdc2-cyclin B1 and polo-lik

292 Although parenchymal amyloid was focally disaggregated, vascular deposits were relatively preserv

293 Climate and the Economy (RICE)-a regionally disaggregated version of the Dynamic Integrated model of

294 onstitution of its RNA binding activity from disaggregated virus-like particles were established.

295 CXCR4 expression on tumor and liver disaggregates was confirmed using a combination of immun

296 oped by compiling the most comprehensive and disaggregated water and economic data from 3243 US count

297 Single-cell aortic disaggregates were prepared from adult chow-fed C57BL/6

298 ed to describe attack occurrence and impact, disaggregated where possible by age, sex, and location.

299 The 60-200 nm globular aggregates disaggregate with an apparent rate constant of approxima

300 severely aggregated endogenous proteins are disaggregated without degradation during recovery from s