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1 identified from the genome of Dictyostelium discoideum.
2 presented by the social amoeba Dictyostelium discoideum.
3 robe (protist), the slime mold Dictyostelium discoideum.
4 heterochromatin of the six chromosomes in D. discoideum.
5 on single cells of the amoeba Dictyostelium discoideum.
6 on-muscle myosin II motor from Dictyostelium discoideum.
7 r development, and ecological dynamics in D. discoideum.
8 ologs (ChdA, ChdB and ChdC) in Dictyostelium discoideum.
9 database for the social amoeba Dictyostelium discoideum.
10 approach in the model organism Dictyostelium discoideum.
11 s including most metazoans and Dictyostelium discoideum.
12 as a role in cell migration in Dictyostelium discoideum.
13 smoregulation as well as cell motility of D. discoideum.
14 tween humans and the protozoan Dictyostelium discoideum.
15 es involved in resistance to predation by D. discoideum.
16 arly decreased resistance to predation by D. discoideum.
17 chemotaxis and cytokinesis in Dictyostelium discoideum.
18 and affects the development of Dictyostelium discoideum.
19 ation by the phagocytic amoeba Dictyostelium discoideum.
20 ays of chemorepellent gradient sensing in D. discoideum.
21 in the developmental cycle of Dictyostelium discoideum.
22 ved between the yeast Pichia pastoris and D. discoideum.
23 pe locus of the model organism Dictyostelium discoideum.
24 ms, Caenorhabditis elegans and Dictyostelium discoideum.
25 he model organism database for Dictyostelium discoideum.
26 for the extraction of RNA from Dictyostelium discoideum.
27 esion during cell migration in Dictyostelium discoideum.
28 and for obtaining nutrients in Dictyostelium discoideum.
29 or tyrosine kinase-like protein, VSK3, in D. discoideum.
30 at are affected by cisplatin treatment of D. discoideum.
31 rom cells of the social amoeba Dictyostelium discoideum.
32 hemotaxis and cell adhesion in Dictyostelium discoideum.
33 ration of the amoeboid form of Dictyostelium discoideum.
34 ve of Pro-143 in the amebazoan Dictyostelium discoideum.
35 le from the volatile bouquet of wild type D. discoideum.
36 of chimaerism experienced by the related D. discoideum.
37 ecies and from the slime mold, Dictyostelium discoideum.
38 in apicomplexan parasites and Dictyostelium discoideum.
39 reduced drug accumulation in transformed D. discoideum.
40 mplex life cycle of the amoeba Dictyostelium discoideum.
41 hemotaxing unicellular amoeba, Dictyostelium discoideum.
42 ior in the model social amoeba Dictyostelium discoideum.
43 ocial stage of an amoeba host, Dictyostelium discoideum.
44 ought after folic acid receptor, fAR1, in D. discoideum.
45 specific function of volatile terpenes in D. discoideum.
46 e systems in the social amoeba Dictyostelium discoideum.
47 visualize polyP extracted from Dictyostelium discoideum.
48 cheating in the social amoeba Dictyostelium discoideum.
49 y studied in the social amoeba Dictyostelium discoideum.
50 of the yeast prion protein Sup35 (NM), in D. discoideum.
55 bprocess of chemorepulsion, in Dictyostelium discoideum-a well characterized model eukaryotic system.
59 molecules that mediate allorecognition in D. discoideum also control the integration of individual ce
61 ny eukaryotic cells, including Dictyostelium discoideum amoebae, fibroblasts, and neutrophils, are ab
62 ss severe during growth within Dictyostelium discoideum amoebae, indicating that the requirement for
66 binding protein (ACBP; AcbA in Dictyostelium discoideum), an unconventionally secreted protein, is de
67 oximately 1-2 mM IC(50) versus Dictyostelium discoideum and a human cell line, indicating selective a
68 most abundant retroelement in Dictyostelium discoideum and constitutes the pericentromeric heterochr
69 ated migration of the amoeboid Dictyostelium discoideum and for the lamellipod-driven migration of hu
70 lism genes confer cisplatin resistance in D. discoideum and in human cells, raised interest in the re
71 me acidification and lysosome activity in D. discoideum and macrophages and reduced early endosomal m
73 lar polyphosphate and reduced survival in D. discoideum and macrophages, and this was reversed by the
75 haracterized chemotactic cells Dictyostelium discoideum and neutrophils, signaling to the cytoskeleto
78 l multicellular development in Dictyostelium discoideum and reconstruct how some of these mechanisms
81 residues follows myosin II in Dictyostelium discoideum) and the water molecule that spans this salt
82 unction within macrophages and Dictyostelium discoideum, and for intrapulmonary proliferation in mice
83 gans, Acathamoeba castellanii, Dictyostelium discoideum, and Galleria mellonella have provided means
84 he genome of the social amoeba Dictyostelium discoideum, and show, with the use of heterologous expre
85 ed Acanthamoeba castellanii or Dictyostelium discoideum, and the intracellular growth defect was comp
86 from the cellular slime mold, Dictyostelium discoideum, and the protozoan parasite, Toxoplasma gondi
92 a, Vermamoeba vermiformis and Dictyostellium discoideum) are permissive to M. bovis infection and tha
93 ds, including the well-studied Dictyostelium discoideum, are amoebae whose life cycle includes both a
94 charomyces pombe and DnmA from Dictyostelium discoideum, are strongly stimulated by prior queuosine (
95 ell as the results of decades of study of D. discoideum as a model for development, allow us to explo
97 Despite widespread interest in Dictyostelium discoideum as a model system, almost no molecular data e
98 -editing occurs at all predicted sites in D. discoideum as evidenced by changes in the sequences of i
100 ignal transduction pathways in Dictyostelium discoideum but Galpha subunit-effector interactions have
101 homologues, PkbA and PkbR1, in Dictyostelium discoideum by phosphorylation of activation loops (ALs)
102 sms: Saccharomyces cerevisiae, Dictyostelium discoideum, Caenorhabditis elegans, Drosophila melanogas
103 ng cells of the social amoebae Dictyostelium discoideum can aggregate and develop into multicellular
105 er clones of the social amoeba Dictyostelium discoideum carry bacteria to seed out new food populatio
108 , which is produced by growing Dictyostelium discoideum cells and inhibits their proliferation, also
109 transport are investigated in Dictyostelium discoideum cells by single particle tracking of fluoresc
110 Upon starvation, individual Dictyostelium discoideum cells enter a developmental program that lead
111 ectional biases in chemotactic Dictyostelium discoideum cells in a flow chamber with alternating chem
113 gocytosed M. smegmatis or M. tuberculosis D. discoideum cells lacking the putative polyphosphate rece
115 th classes of RNR genes were expressed in D. discoideum cells, although the class I transcripts were
116 l cyclase (ACA) at the back of Dictyostelium discoideum cells, an essential determinant of their abil
117 en imaging rapid morphological changes in D. discoideum cells, as well as improved contrast and resol
119 t varies across cell types: in Dictyostelium discoideum cells, it is mediated by biochemical signalin
120 of cytokinesis, in rounded-up Dictyostelium discoideum cells, the small G-protein Rap1 is activated
126 nsport within the cytoplasm of Dictyostelium discoideum cells: the anomalous non-linear scaling of th
128 ies of the diiron-oxo/radical cofactor of D. discoideum class I RNR are similar to those of the mamma
131 holderia inhibit the growth of non-farmer D. discoideum clones that could exploit the farmers' crops.
135 Here, we show that the amoeba Dictyostelium discoideum coordinates Ras and Rac activity using the mu
136 65) of the myosin-2 motor from Dictyostelium discoideum (Dd) is proposed to be a key residue in an al
138 gelation factor (ABP-120) from Dictyostelium discoideum (ddFLN5) by NMR spectroscopy to provide a bas
139 ly regulated Na-H exchanger in Dictyostelium discoideum (DdNHE1) localizes to the leading edge of pol
140 re, we demonstrate that peroxidase A from D. discoideum (DdPoxA) is a stable, monomeric, glycosylated
141 that class I is the principal RNR during D. discoideum development and growth and is important for s
142 face cAMP receptors throughout Dictyostelium discoideum development, controlling chemotaxis and morph
144 s, including the social amoeba Dictyostelium discoideum, development is often marked by dynamic morph
146 zymes, such as PDE for cAMP in Dictyostelium discoideum (Dicty) and BAR1 for mating factor alpha in S
147 We have engineered a mutant of Dictyostelium discoideum (Dicty) myosin II that contains the same fast
152 turally occurring genotypes of Dictyostelium discoideum during the formation of chimeric fruiting bod
153 ectly observe the structure of Dictyostelium discoideum dynein dimers on microtubules at near-physiol
155 s, including the social amoeba Dictyostelium discoideum, encode both a class I and a class II RNR.
157 ed vesicles from mutant-PfCRT-transformed D. discoideum exhibit features of the CQR phenotype, consis
160 e results change our understanding of the D. discoideum farming symbiosis by establishing that the ba
163 shown that a little-studied component of D. discoideum fitness--the loner cells that do not particip
164 Schizosaccharomyces pombe and Dictyostelium discoideum for methylation of the Geobacter tRNA-Asp and
166 We show that the non-metazoan Dictyostelium discoideum forms a polarized epithelium that is essentia
171 FPPS from Leishmania major, in Dictyostelium discoideum growth inhibition, in gammadelta T cell activ
173 we show that the social amoeba Dictyostelium discoideum has a primitive farming symbiosis that includ
174 e show that the model organism Dictyostelium discoideum has evolved to normally encode long polygluta
176 nformatics tools, we show that Dictyostelium discoideum has the highest content of prion-like protein
179 at control the developmental programme of D. discoideum, highlighting the central role of cAMP in the
180 KrsB interacts genetically with another D. discoideum Hippo/MST homolog, KrsA, but the two genes ar
182 teins remain soluble and are innocuous to D. discoideum, in contrast to other organisms, where they f
183 the model developmental system Dictyostelium discoideum, in which Ca(2+) plays a role in receptor-reg
184 ife cycle of the social amoeba Dictyostelium discoideum includes a multicellular stage in which not n
185 PtdInsP(3)-binding proteins in Dictyostelium discoideum, including five pleckstrin homology (PH) doma
187 main and the evidence for TPS function in D. discoideum indicate that the TPS genes mediate lineage-s
188 behavior of the model organism Dictyostelium discoideum indicate the biocompatibility of the function
189 advantage in the amoebal host Dictyostelium discoideum, indicating that the protein family may modul
190 ith starvation, the amoebae of Dictyostelium discoideum initiate a developmental process that begins
192 gregation of the social amoeba Dictyostelium discoideum into a multicellular slug is known to result
194 The microbial soil amoeba Dictyostelium discoideum is a model system for the study of social evo
202 psulation of prespore cells of Dictyostelium discoideum is controlled by several intercellular signal
203 he genome of the social amoeba Dictyostelium discoideum is known to have a very high density of micro
206 te and define social interactions between D. discoideum isolates, thus providing a conceptual framewo
209 ed for cellular ion imaging in Dictyostelium discoideum live cells but spontaneous dye loss resulted
212 we show that WASH coats mature Dictyostelium discoideum lysosomes and is essential for exocytosis of
213 a genetic interaction between Dictyostelium discoideum mek1, smkA (named for its role in the suppres
214 ng member), Homo sapiens RNF4, Dictyostelium discoideum MIP1 and Saccharomyces cerevisiae Slx5-Slx8.
216 modification pathway exists in Dictyostelium discoideum, model of the evolutionary superfamily Amoebo
217 el of the contraction phase of Dictyostelium discoideum motility with an emphasis on the adhesive pro
220 One such residue is Ser236 (Dictyostelium discoideum myosin II numbering) which was proposed to be
222 e show that in the nonmetazoan Dictyostelium discoideum, myosin II localizes apically in tip epitheli
223 associated Burkholderia isolates colonize D. discoideum nonfarmers and infectiously endow them with f
228 analysis revealed that cAMP signalling in D. discoideum originated from a second messenger role in am
229 n this study we identified the Dictyostelium discoideum ortholog of the adaptor protein AP180 and cha
230 the mycetozoan model organism Dictyostelium discoideum Our results show that phenamacril potently (I
231 only partially restored aggregation of a D. discoideum pdsA-null mutant, but was more effective at r
234 lug stage of the social amoeba Dictyostelium discoideum produce ETs upon stimulation with bacteria or
236 that, in contrast to observations made in D discoideum, PTEN-null Jurkat T cells exhibited potent ch
237 this study, PKAR and PDE from Dictyostelium discoideum (RD and RegA, respectively) were used as a mo
238 dicates that the social amoeba Dictyostelium discoideum recognizes distinctions between Gram(-) and G
239 ediction for the social amoeba Dictyostelium discoideum; relatedness in natural wild groups is so hig
241 nicellular phagocytic organism Dictyostelium discoideum reveal that, like OCRL, the Dictyostelium OCR
242 ement of volatile terpenes in cultures of D. discoideum revealed essentially no emission at an early
245 ings identified the slime mold Dictyostelium discoideum's CISD proteins as the closest to the ancient
246 sapiens, Arabidopsis thaliana, Dictyostelium discoideum, Saccharomyces cerevisiae, Escherichia coli a
247 We show that, unexpectedly, Dictyostelium discoideum SCAR knockouts could still spread, migrate, a
248 he "turbine wave." Herein we argue that a D. discoideum scroll or concentric wave territory containin
250 Although intravesicular pH levels in D. discoideum show small acidic changes with the expression
251 periments on the social amoeba Dictyostelium discoideum show that the origins of lineage bias in this
253 terologous expression, all nine TPSs from D. discoideum showed sesquiterpene synthase activities.
256 Burkholderia inside and outside colonized D. discoideum spores after fruiting body formation; this ob
259 ogenomic approach we have determined that D. discoideum TalA/B and the animal talins are related by d
260 behaviors in the social amoeba Dictyostelium discoideum, testing whether these genes experience rapid
261 is review is one discovered in Dictyostelium discoideum that becomes an actin-like fiber concurrent w
262 er" clone of the social amoeba Dictyostelium discoideum that carries and disperses bacteria during it
263 ysis of the isolated MTBD from Dictyostelium discoideum that demonstrates the coiled-coil beta(+) reg
264 n Elmo-like protein, ElmoA, in Dictyostelium discoideum that unexpectedly functions as a negative reg
265 model for cAMP oscillations in Dictyostelium discoideum, the cell-cycle data for Saccharomyces cerevi
266 psulation in the social amoeba Dictyostelium discoideum, the metabolic profile and other potential fu
268 mycetozoan eukaryotes such as Dictyostelium discoideum This social amoeba kills bacteria via phagocy
269 esis in the social soil amoeba Dictyostelium discoideum Through genome sequencing, we successfully id
270 R-E test in the model organism Dictyostelium discoideum to demonstrate that Dync1li1 is an essential
271 part of a regulatory network that allows D. discoideum to elicit specific cellular responses to diff
274 3) is not only unnecessary for Dictyostelium discoideum to migrate toward folate, but actively inhibi
275 athways, such as those used by Dictyostelium discoideum to move toward cAMP, use a G protein-coupled
276 In this paper, we exploit Dictyostelium discoideum to uncover a novel role for PARylation in reg
277 we employ a simple eukaryote, Dictyostelium discoideum, to demonstrate distinct effects of loss of I
285 ling network for chemotaxis in Dictyostelium discoideum We identified a negative regulator of Ras sig
287 reen for chemotaxis mutants in Dictyostelium discoideum, we identified a loss-of-function mutation, d
288 ng a forward genetic screen in Dictyostelium discoideum, we identified the Ste20 kinase KrsB, a homol
290 late multicellular development stages of D. discoideum when migrating slugs differentiate into fruit
291 munication in the social ameba Dictyostelium discoideum when the solitary cells aggregate to form mul
292 ect on the accumulation of chloroquine by D. discoideum, whereas forms of PfCRT carrying a key charge
293 nipulated in the social amoeba Dictyostelium discoideum, which allows us to test and confirm the two
295 his evolutionary hypothesis in Dictyostelium discoideum, which forms multicellular fruiting bodies by
296 ped diversity of natural products made by D. discoideum, which may have diverse roles in its developm
297 hibitor (EC(50) >/= 50 muM) in Dictyostelium discoideum, while the strongest interactant was found to
300 tide-binding site of wild-type Dictyostelium discoideum (WT) myosin and a construct containing a sing