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1             The best characterised of these, discoidin 1, is a marker of the growth-development trans
2 ologous to Dictyostellium discoideum protein discoidin 1.
3 ibodies found in these patients targeted the discoidin and laminin G1 domains of CASPR2 and always in
4 ing two genes-ONECUT2 and an uncharacterized discoidin- and thrombospondin-containing protein.
5 , as do truncated SED1 proteins containing a discoidin/C domain.
6 e studies illustrate that Notch-like EGF and discoidin/C domains, protein motifs that facilitate a va
7                                          The discoidin C2 domains of coagulation factors V and VIII a
8 membrane-targeting domains (Annexin, C1, C2, discoidin C2, PH, PX), enzymes (PLA, PLC/D) and lipid-tr
9                Each subunit is composed of a discoidin domain and a small N-terminal (RS1) domain.
10                                          The discoidin domain and PTK core of DDR-2 were essential fo
11 cid protein, retinoschisin, which contains a discoidin domain but is of unknown function.
12 to the polypeptide chain termini of the DDR2 discoidin domain constitutes the collagen recognition si
13             Receptor tyrosine kinases of the discoidin domain family, DDR1 and DDR2, are activated by
14 y that used wild-type and mutant forms of RS discoidin domain glutathione S-transferase (GST) fusion
15                                          The discoidin domain has been identified in mammalian milk f
16  studies determined selective binding to the discoidin domain of CASPR2.
17 heir extracellular domains, and the isolated discoidin domain of DDR2 bound collagen I with high affi
18                             Furthermore, the discoidin domain of DDR2, but not of DDR1, was sufficien
19  To map the collagen binding site within the discoidin domain of DDR2, mutant constructs were created
20 ted to change the amino acid sequence in the discoidin domain of the retinoschisin protein.
21                                Activation of discoidin domain receptor (DDR) 1 by collagen is reporte
22                                              Discoidin domain receptor (DDR) 1 is a receptor tyrosine
23 collagen receptors, alpha2beta1 integrin and discoidin domain receptor (DDR) 1.
24                                          The discoidin domain receptor (DDR) is a new class of recept
25 ified the conserved receptor tyrosine kinase Discoidin domain receptor (Ddr).
26                                          The discoidin domain receptor (DDR1) is characterized by a d
27  receptors on the tumor cells, including the discoidin domain receptor 1 (DDR1) and E-Cadherin (E-Cad
28                                              Discoidin domain receptor 1 (DDR1) belongs to a unique f
29 he expression of the novel collagen receptor discoidin domain receptor 1 (DDR1) by human MKs at both
30 ss, we identified a receptor tyrosine kinase discoidin domain receptor 1 (DDR1) expressed in granule
31                                              Discoidin domain receptor 1 (DDR1) is a collagen recepto
32                                              Discoidin domain receptor 1 (DDR1) is a collagen recepto
33                                              Discoidin domain receptor 1 (DDR1) is a collagen-activat
34                                              Discoidin domain receptor 1 (DDR1) is a key sensor of CO
35                                              Discoidin domain receptor 1 (DDR1) is a nonintegrin coll
36                                              Discoidin domain receptor 1 (DDR1) is a receptor tyrosin
37                                              Discoidin domain receptor 1 (DDR1) is a receptor tyrosin
38                                              Discoidin domain receptor 1 (DDR1) is a receptor tyrosin
39                                              Discoidin domain receptor 1 (DDR1) is a unique collagen-
40                                              Discoidin domain receptor 1 (DDR1) is a widely expressed
41                                          The discoidin domain receptor 1 (DDR1) is activated by colla
42 e also identified that the downregulation of discoidin domain receptor 1 (DDR1) is synthetically leth
43  simultaneous delivery of mRNA encoding anti-discoidin domain receptor 1 (DDR1) single-chain variable
44                            Here we show that discoidin domain receptor 1 (DDR1), a collagen receptor
45                           Here, we show that Discoidin Domain Receptor 1 (DDR1), a collagen receptor
46  RNAi sensitization screen, which identified discoidin domain receptor 1 (DDR1), a collagen-activated
47                  Significantly, knockdown of discoidin domain receptor 1 (DDR1), a collagen-binding p
48                  We previously reported that discoidin domain receptor 1 (DDR1), a nonintegrin collag
49 on of Wnt5a, but also the phosphorylation of discoidin domain receptor 1 (Ddr1), a receptor for colla
50                                              Discoidin domain receptor 1 (DDR1), a receptor tyrosine
51 esumed progenitors of HRS cells, upregulates discoidin domain receptor 1 (DDR1), a receptor tyrosine
52 iated melanocyte localization, we identified discoidin domain receptor 1 (DDR1), a receptor tyrosine
53 volving latent membrane protein 1 (LMP1) and discoidin domain receptor 1 (DDR1), which is activated b
54                     Whereas cCol I activates discoidin domain receptor 1 (DDR1)-NF-kappaB-p62-NRF2 si
55 moural hepatocytes and through activation of discoidin domain receptor 1 in established tumours.
56 Ruggeri et al that reports the importance of discoidin domain receptor 1 in tissue homeostasis in pan
57                                              Discoidin domain receptor 1 tyrosine kinase (DDR1) and t
58 lagen-binding receptor tyrosine kinase DDR1 (discoidin domain receptor 1) is a drug target for a wide
59                                        DDR1, discoidin domain receptor 1, belongs to a subfamily of t
60 mechanical cue is transduced sequentially by discoidin domain receptor 1, c-Jun N-terminal kinase 1,
61 ivation of collagen receptors, integrins and discoidin domain receptor 1, play a role in disease prop
62 vestigate the relationship between increased discoidin domain receptor 2 (DDR-2) expression and carti
63 d MMP-13, degraded type II collagen, and the discoidin domain receptor 2 (DDR-2) in knee joints.
64 nvestigate the role of the collagen receptor discoidin domain receptor 2 (DDR-2) in the pathogenesis
65 hat a majority of human melanoma overexpress discoidin domain receptor 2 (DDR2) after treatment.
66                 In this study, we identified discoidin domain receptor 2 (DDR2) as a crucial receptor
67 ion of the tyrosine-kinase collagen receptor discoidin domain receptor 2 (DDR2) has no impact on huma
68 llular domain (ECD) of the collagen receptor discoidin domain receptor 2 (DDR2) inhibits fibrillogene
69                                              Discoidin domain receptor 2 (DDR2) is a collagen-activat
70                                              Discoidin domain receptor 2 (DDR2) is a receptor tyrosin
71                                              Discoidin domain receptor 2 (DDR2) is a tyrosine kinase
72                                              Discoidin domain receptor 2 (DDR2) is an unusual recepto
73 et al demonstrate that the collagen receptor Discoidin domain receptor 2 (DDR2) promotes neutrophil c
74                  Increased expression of the discoidin domain receptor 2 (DDR2) results from its inte
75 ptomic and proteomic analyses, we identified discoidin domain receptor 2 (DDR2), a cell surface recep
76                                              Discoidin domain receptor 2 (DDR2), a collagen receptor
77                      The collagen receptors, discoidin domain receptor 2 (DDR2), a collagen-specific
78                                              Discoidin domain receptor 2 (DDR2), an understudied coll
79 lated proteins: von Willebrand factor (VWF), discoidin domain receptor 2 (DDR2), and the extracellula
80 ression of a cell surface collagen receptor, discoidin domain receptor 2 (DDR2), is increased in chon
81 e show that the fibrillar collagen receptor, Discoidin Domain Receptor 2 (DDR2), promotes collagen pr
82 2, or collagen deglycosylation that prevents discoidin domain receptor 2 activation allowed cells to
83 t involves activation of the tyrosine kinase discoidin domain receptor 2 and is independent of effect
84                                              Discoidin domain receptor 2 expression was unchanged, bu
85                             Mutations in the discoidin domain receptor 2 gene (DDR2), which encodes a
86 RNA and also used to determine the amount of discoidin domain receptor 2 mRNA in cardiac tissue.
87 c), thymocyte differentiation antigen 1, and discoidin domain receptor 2).
88 tin, procollagen I, fibronectin I, vimentin, discoidin domain receptor 2, and tenascin C, markers of
89 nase inhibitor genistein, down-regulation of discoidin domain receptor 2, or collagen deglycosylation
90                                              Discoidin domain receptor tyrosine kinase 1 induces stem
91                                        DDR1 (discoidin domain receptor tyrosine kinase 1) kinase s hi
92 -trisphosphate receptor, type 3 (ITPR3), and discoidin domain receptor tyrosine kinase 2 (DDR2).
93 taining, and up-regulated mRNA expression of discoidin domain receptor tyrosine kinase 2, fibronectin
94                                              Discoidin domain receptor tyrosine kinase, activated by
95 inkage, also activates the collagen receptor discoidin domain receptor-2 (DDR-2) in both the utse and
96 drocyte responses through receptors, such as discoidin domain receptor-2 and syndecan-4.
97 gen I activates fibroblast collagen receptor discoidin domain receptor-2, contributes significantly t
98 ed growth factor receptors (PDGFRs), and the discoidin domain receptor.
99                                              Discoidin domain receptors (DDR) 1 and 2 represent a fam
100                                              Discoidin domain receptors (DDR1 and DDR2) are receptor
101                                              Discoidin domain receptors (DDR1 and DDR2) are receptor
102                                              Discoidin domain receptors (DDR1 and DDR2) are the colla
103                                              Discoidin domain receptors (DDR1 and DDR2) are widely ex
104 have recently been identified as ligands for discoidin domain receptors (DDR1 and DDR2), generating a
105                                          The discoidin domain receptors (DDRs) are receptor tyrosine
106                                          The discoidin domain receptors (DDRs) are receptor tyrosine
107                                          The Discoidin Domain Receptors (DDRs) constitute a unique se
108                                  The role of Discoidin Domain Receptors (DDRs) is poorly understood i
109 study, we found that collagen binding by the discoidin domain receptors (DDRs) requires dimerization
110                                    The human discoidin domain receptors (DDRs), DDR1 and DDR2, are ex
111               The widely expressed mammalian discoidin domain receptors (DDRs), DDR1 and DDR2, are un
112                                          The discoidin domain receptors (DDRs), DDR1 and DDR2, form a
113                                              Discoidin domain receptors 1 and 2 (DDR1/2) play a centr
114                                          The discoidin domain receptors, DDR1 and DDR2, are nonintegr
115                                          The discoidin domain receptors, DDR1 and DDR2, are receptor
116   Collagens and their cognate receptors, the discoidin domain receptors, have a role in various steps
117 mino acid mutation and insertion in the ACLP discoidin domain regulates collagen binding and assembly
118 ecific secreted protein encoding a conserved discoidin domain sequence.
119              Here, we tested the role of the discoidin domain tyrosine kinase receptor 2 (DDR2), whic
120 ially adjacent surface loops within the DDR2 discoidin domain were found to be critically involved in
121 s thrombospondin repeats, a collagen-binding discoidin domain, and a catalytically inactive metalloca
122 the stability and cell-surface expression of discoidin domain-containing receptor 2 (DDR2) in breast
123  lineage CSC(1) (CTSK(+) CSC) and a separate discoidin domain-containing receptor 2 (DDR2) lineage st
124  ligands for the previously orphan family of discoidin domain-containing receptor-like tyrosine kinas
125                                              Discoidin domain-containing receptors (DDRs) exhibit a u
126 coded by 8 exons of which three code for the discoidin domain.
127 by recombinant Mfge8 containing at least one discoidin domain.
128  direct interaction of collagen with the DDR discoidin domain.
129 elical collagen and was mediated by the DDR2 discoidin domain.
130  show that the TVC-specific collagen-binding Discoidin-domain receptor (Ddr) cooperates with Integrin
131 odies in the CSF targeted the laminin G1 and discoidin domains of CASPR2 in all patients.
132 orresponding loops of functionally unrelated discoidin domains.
133 growth factor repeats, an RGD motif, and two discoidin domains.
134 ing collagen for cellular uptake through its discoidin domains.
135  inhibitor protein (RKIP), DDR-2 lacking the discoidin (DS) domain (DeltaDS-DDR-2) or the protein tyr
136 eins that contain Notch-like EGF repeats and discoidin/F5/8 type C domains.
137 cond of which contains an RGD motif) and two discoidin/Factor V/VIII C domains.
138                           The DDRs contain a discoidin homology domain in their extracellular domains
139 stelium discoideum, we previously identified Discoidin I (DscI), a classic secreted lectin, as a CK c
140 xtracellular domain homologous to the lectin Discoidin I found Dictyostelium discoideum.
141 the TAs of the leading cell, suggesting that discoidin I is not responsible for a possible chemically
142 domain receptor (DDR1) is characterized by a discoidin I motif in the extracellular domain, an unusua
143              Cells not expressing the lectin discoidin I or moving on discoidin I-coated substrata fo
144 pressing the lectin discoidin I or moving on discoidin I-coated substrata form fewer tandems, but the
145 rosine kinase-3 ligand, EGF-like repeats and discoidin I-like domains 3, and intercellular adhesion m
146 that of the Dictyostelium discoideum protein discoidin I.
147 (altered RGD domain), Del-1 minor (truncated discoidin-I-like domain), or basic fibroblast growth fac
148 motif and a second signaling sequence in the discoidin-I-like domain.
149          This defect correlated with loss of discoidin Igamma mRNA, a starvation-induced gene, althou
150                 Therefore, both ACLP and its discoidin-like domain may be novel targets for anti-myof
151         Finally, the addition of recombinant discoidin-like domain of ACLP to cultured ACLP-deficient
152 roline-rich 11-amino acid repeating motif, a discoidin-like domain, and a C-terminal domain with 39%
153 (ACLP), a collagen-associated protein with a discoidin-like domain, is expressed at high levels in hu
154 -helix, an insertion domain and a C-terminal discoidin-like domain.
155 idermal growth factor (EGF)-like repeats and discoidin-like domains 3 (EDIL3) and milk fat globule-EG
156 ermal growth factor (EGF)-like repeats and 2 discoidin-like domains.
157              The lactadherin C2 domain has a discoidin-like fold containing two beta-sheets of five a
158           We determined the structure of the discoidin rings, consistent with known intramolecular an
159 , contains tandem C domains with homology to discoidin-type lectins and to membrane-binding domains o

 
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