ライフサイエンスコーパス: disconnection

1 ("ipsilateral") or in opposite hemispheres ("disconnection").

2 teral ablations of these regions (functional disconnection).

3 of stream-aquifer systems from connection to disconnection.

4 defined as post-stroke necrosis or cortical disconnection.

5 powerful and generally useful retrosynthetic disconnection.

6 L-6), depressed mood, and feelings of social disconnection.

7 ses in depressed mood and feelings of social disconnection.

8 ses in depressed mood and feelings of social disconnection.

9 es in neural dynamics result from structural disconnection.

10 onset as a method to standardize the axonal disconnection.

11 lation in the Fas death pathway after target disconnection.

12 and especially in patients with hemispheric disconnection.

13 between synaptic dysfunction and functional disconnection.

14 was clearly superior to indirect functional disconnection.

15 described as precursors of glomerulotubular disconnection.

16 e lost through a process of glomerulotubular disconnection.

17 lesion and indirect structural or functional disconnection.

18 sed by structural, functional, and metabolic disconnection.

19 se from cortical damage or from white matter disconnection.

20 mple molecules and providing novel synthetic disconnections.

21 huffle mechanisms through gliding four-layer disconnections.

22 ic increase in both provascular and vascular disconnections.

23 define the loci of potential retrosynthetic disconnections.

24 zing complex molecules using non-traditional disconnections.

25 ly stereotyped spatial distribution of brain disconnections.

26 werful concept of prioritized strategic bond disconnections.

27 can act as effective nucleation sites of GB disconnections.

28 First, using an alternative disconnection, a hemiketal conjugate addition to a napht

29 Neither sensory stimulation nor disconnection alone generated significant eyeblink respo

30 Moreover, these disconnections also each reduced responding and motivati

31 be trends in medical exemptions from utility disconnection and characteristics and health care use of

32 eed, the neurocognitive correlates of social disconnection and connection may be important mediators

33 We used disconnection and neuroanatomical techniques to reveal t

34 why the dreaming brain may undergo executive disconnection and remain asleep.

35 ns presented are organized according to bond disconnections and attendant synthetic methods.

36 Here we combined functional disconnections and electrophysiological recordings of th

37 oy typical as well as Umpolung types of bond disconnections and have served as the key step in severa

38 ith respect to drug discovery, new MCR-based disconnections and often hidden opportunities.

39 enable chemists to unveil new retrosynthetic disconnections and streamline conventional synthetic app

40 in practice distorted by unmodelled network disconnections and strong 'parasitic' dependencies betwe

41 eality and efficiency led to several unusual disconnections and tactics.

42 that perceived stress, sensitivity to social disconnection, and depressive symptoms were associated w

43 erceived stress, trait sensitivity to social disconnection, and severity of symptoms of anxiety and d

44 ent and reacquisition we used a chemogenetic disconnection approach and show that silencing either th

45 Here, we used a functional disconnection approach to temporarily disrupt the PL-RMT

46 -dependent manner, we used a pharmacological disconnection approach whereby dopamine signaling was bl

47 Using a selective disconnection approach, we reveal that D1 and D2 recepto

48 y that releases CRF was investigated using a disconnection approach.

49 recover neurological deficits caused by axon disconnection are extremely limited.

50 ene, yet the exact nature and timing of this disconnection are not well understood.

51 In planning organic syntheses, disconnections are most often made adjacent to functiona

52 tudy suggests that frontoparietal functional disconnections are specifically observed in coma and the

53 d its relation with the exhibited functional disconnections are very poorly understood.

54 as the presence of neurofibrillary tangles, disconnection, as well as compensation processes.

55 persensitivity is associated with functional disconnection (asynchrony) between the thalamus and cort

56 This disconnection attenuated cue-induced reinstatement of co

57 The disconnection between a reaction's development and the q

58 mulations indicated that this delay caused a disconnection between attenuation of the antiviral respo

59 thway, suggesting that there is a functional disconnection between both structures in adult KO mice.

60 l pathways in an animal model to address the disconnection between brain regions as a mechanism for w

61 ey can help buffer the effects of hydrologic disconnection between catchments and lakes but at the co

62 To investigate the disconnection between observed CD8 T-cell responses and

63 fossils are unknown, which has resulted in a disconnection between the body- and trace-fossil records

64 Functional disconnection between the hippocampus and other componen

65 anent impairment of sensory functions due to disconnection between the peripheral and central nervous

66 ction of the basal ganglia motor circuit and disconnection between the rostral supplementary motor ar

67 lance due to MS appears to be related to the disconnection between the spinal cord, cerebellum, and c

68 eferential processes (OFC, PCC), but also to disconnection between these regions as well as with the

69 was most attributable to longer duration of disconnection between upstream and downstream habitats,

70 Disconnections between in vitro responses and those obse

71 In contrast, disconnections between the BLA and PFC increased choice

72 of basal ganglia motor circuit together with disconnections between the rostral supplementary motor a

73 tivity of those tasks to prefrontal-temporal disconnection by adding specific temporal components to

74 ion for death receptor pathways after target disconnection by axotomy vs. disease progression.

75 lly in the OFC or generated an OFC-amygdala "disconnection" by pairing unilateral OFC Bdnf knockdown

76 This concept of developmental disconnection can accommodate the specific neurobehavior

77 l afferent, and progressive cortico-striatal disconnection characterizes HD.

78 sented a selective bilateral parietotemporal disconnection, compared with GRN- patients.

79 Failure to account for this spatial disconnection could lead to potentially misleading concl

80 strain gauge, new sensing mechanisms include disconnection, crack propagation, and tunneling effects

81 We used a crossed-disconnection design in which monkeys received amygdala

82 However, indirect estimation of functional disconnection did not predict behavioural deficits, nor

83 PFC-NAc disconnections did not affect choice but did increase ch

84 ain injury (TBI) is a pre-eminent structural disconnection disorder whereby traumatic axonal injury d

85 natomical and temporal signatures of sensory disconnection during sleep and pave the way to understan

86 presents a novel neural correlate of sensory disconnection during sleep, opening new avenues for inve

87 stration of linear block, and pulmonary vein disconnection during the initial AF procedure.

88 --> 10 are pseudopericyclic with two orbital disconnections each, whereas the 13 --> 14 and 15 --> 16

89 with focal epilepsy-that inherently capture disconnection effects, and whose structural dependence p

90 apacity, whereas thalamo-cortical functional disconnections emerge during states of higher segregatio

91 Mitigating the risk by partial disconnection endangers their functionality.

92 First, using a disconnection experiment, we show that the BLA and dopam

93 Functional disconnection experiments (Daun02 lesioning of vmPFC and

94 In contrast, monkeys that sustained MDm disconnection failed to adjust their object choices.

95 L-6 were correlated with increases in social disconnection for females but not for males.

96 on cascade introduces a novel retrosynthetic disconnection for the assembly of substituted lactams an

97 These results provide a new retrosynthetic disconnection for the construction of enantioenriched ci

98 This catalytic reaction provides a new disconnection for the convergent synthesis of tertiary a

99 for medicinal chemists, providing a modular disconnection for the rapid diversification of heteroaro

100 This finding provides a novel disconnection for the synthesis of pyridine-containing a

101 l and heteroaryl systems, representing a new disconnection for the synthesis of this versatile moiety

102 mplications on unconventional strategic bond disconnections for preparing complex cyclic molecules.

103 methodology will inspire new retrosynthetic disconnections for substituted amine derivatives in orga

104 tance(18), but this does not explain why the disconnections form primarily on positive leaders(22), o

105 ease of thalamus centrality results from its disconnection from a widespread set of cortical and subc

106 nisms underlying human consciousness and its disconnection from behavioral responsiveness, both durin

107 the estimation of structural and functional disconnection from clinical structural imaging.

108 parahippocampus showed evidence of transient disconnection from cortical brain regions involved in me

109 ageous outcome probably being related to its disconnection from crucial language processing pathways.

110 to determine whether patients are ready for disconnection from mechanical ventilation, but mode and

111 f immersion in nature, and the corresponding disconnection from multi-media and technology, increases

112 t conditions of internal node failure due to disconnection from nodes within its own network.

113 ynaptic VAChT and Chrna2 was correlated with disconnection from Renshaw cells as well as major struct

114 Although not perceived, the blink-induced disconnection from the visual environment leads to a los

115 anner that does not result in their death or disconnection from their targets but nonetheless alters

116 ns, where both single-layer and double-layer disconnections have important contributions to the GB mi

117 the ipsilateral (control) or contralateral (disconnection) hemisphere.

118 Using a new bond disconnection, here we report a concise synthesis of the

119 It features a unique strategy for the key disconnection, highlighting a modified Negishi carboalum

120 This finding supports the disconnection hypothesis of unilateral neglect and has i

121 We propose a disconnection hypothesis, wherein focal vascular damage

122 We suggest that prefrontal-temporal disconnection impairs a wide variety of learning tasks b

123 We then examined tract disruption and disconnection in a subset of eight patients who underwen

124 hyperconnectivity driving eventual profound disconnection in AD and suggest that this is present dec

125 te an implication of caudal interhemispheric disconnection in chronic neglect.

126 acidic conditions is an entrenched synthetic disconnection in organic chemistry.

127 matory cytokines, depressed mood, and social disconnection in response to an inflammatory challenge.

128 esults confirm a key role of fronto-parietal disconnection in the emergence and chronic persistence o

129 rosis (MS) that might result from functional disconnection in the frontocerebellar loop.

130 understanding the role of peripheral target disconnection in the pathogenesis of ALS.

131 vanishes when anesthetics produce functional disconnection in this posterior complex, interrupting co

132 Electron microscopy reveals unit disconnections in a low albite grain boundary, defects i

133 The key disconnections in our synthetic approach include an enan

134 paspaline present a series of new synthetic disconnections in preparing steroidal natural products.

135 ibed herein outline complementary conceptual disconnections in the arena of steroid natural product s

136 e transformations could offer strategic bond disconnections in the synthesis of complex bioactive mol

137 x catalysis has redefined the available bond disconnections in the synthetic arsenal.

138 Pseudocoarctate transition states exhibit disconnections in the topology of orbital overlap and do

139 bonds can enable entirely new retrosynthetic disconnections in the total synthesis of natural product

140 im to highlight the strategic value of these disconnections in their respective settings and to ident

141 reating CNS injuries characterized by axonal disconnection including spinal cord injury.

142 on, the mSOD1 facial nucleus displays target disconnection-induced gene expression changes that mirro

143 A strategic disconnection involving an unusual C sp3 -C sp2 Suzuki-M

144 Melancholia was characterized by a pervasive disconnection involving anterior insula and attentional

145 ognition, it is likely that glomerulotubular disconnection is an underappreciated mechanism in the pr

146 roblem for movement of the critical point of disconnection is established for an analytical solution

147 The scope of this previously unknown bond disconnection is highlighted through the development of

148 The DMN-TPJ disconnection is instead linked to the volumetric proper

149 ial attention and inhibitory control using a disconnection lesion approach.

150 The disconnection lesion led to both impulsive and compulsiv

151 Iowa Gambling task, we used a contralateral disconnection lesion procedure to assess whether functio

152 Monkeys that sustained NA disconnection, like controls, showed robust shifts in ob

153 C on OFC-BLA interactions using a functional disconnection manipulation.

154 Both lesion and indirect structural disconnection maps were predictive of behavioural impair

155 possibility that feelings of chronic social disconnection may be mirrored by a "lonelier" neural sel

156 Splenial disconnection may prevent fronto-parietal networks in th

157 tions in neurotransmitters signaling (or its disconnection) may favor a correspondent functional reor

158 We further demonstrate that the disconnection-mediated GB migration is fully reversible

159 Such disconnection-mediated GB migration should represent a g

160 onist muscimol into ventral pallidum (i.e., "disconnection" methods) also impaired response output, i

161 These findings suggest that fronto-parietal disconnection might be particularly relevant for coma ou

162 s to reveal energetically feasible synthetic disconnections, minimizing time-consuming and expensive

163 on preventing IV infusion identification and disconnection mix-ups.

164 Following PFC-IT disconnection monkeys were severely impaired at reacquir

165 ysfunction (n = 22), and those with callosal disconnection (n = 7).

166 ysfunction (n = 22), and those with callosal disconnection (n = 7).

167 There were 6 telemedicine disconnections, none of which lasted longer than 60 seco

168 onalized aryl ring, this constitutes a novel disconnection of a pharmaceutically important scaffold.

169 on bond forming cycles that enable a modular disconnection of a target structure into cellular buildi

170 date, to study the consequences of complete disconnection of abdominal vagal afferents on innate anx

171 This behavior is disrupted by the disconnection of amygdala pathways to the lateral hypoth

172 n of the uncinate may represent insufficient disconnection of an anterior temporal epileptogenic netw

173 recognition impairment and (2) the degree of disconnection of association fiber tracts [inferior long

174 ith pyrimidine and pyridine systems allows a disconnection of catalysis from autocatalysis, providing

175 reversible-covalent chemistry to prompt the disconnection of chemical bonds and the formation of new

176 Disconnection of cognitively important processing region

177 symptomatic mice show significant functional disconnection of dMSNs from motor cortex without changes

178 nigrostriatal lesions induced a significant disconnection of dMSNs from the motor cortex.

179 After disconnection of fixtures and abutments, microbial sampl

180 After disconnection of fixtures and abutments, microbial sampl

181 Further dilution induces a functional disconnection of light-harvesting complex (LHC) II from

182 These findings provide a mechanism for disconnection of long-distance pathways, excessive conne

183 Chemogenetic disconnection of monosynaptic glutamatergic vCA1 to mPFC

184 fter traumatic brain injury results from the disconnection of network hubs by traumatic axonal injury

185 Our results suggest that disconnection of network hubs led to a less efficient ne

186 and/or amplify neurodegeneration-associated disconnection of neuronal circuitries.

187 er-value food; monkeys with crossed surgical disconnection of OFC and the amygdala did not.

188 Functional disconnection of PL-RMTg via contralateral inactivation

189 rontal function in monkeys have shown that a disconnection of prefrontal cortex from inferior tempora

190 The increase in alpha activity and the disconnection of SI from frontoparietal areas are likely

191 ns with lateral hypothalamus and showed that disconnection of that system abolished CPF.

192 onsated) food, monkeys with crossed surgical disconnection of the amygdala and OFC did not.

193 ablished structural connectivity to simulate disconnection of the amygdala.

194 Disconnection of the BA and the NAccSh was just as effec

195 s found that with concurrent pharmacological disconnection of the cerebellar cortex and intense senso

196 cer uptake during a seizure, with a relative disconnection of the epileptogenic temporal lobe in the

197 urthermore, we show that only the electrical disconnection of the ESI probe from the FFE-MS transfer

198 in the default network including functional disconnection of the hippocampal formation.

199 ted that these correlations result from some disconnection of the hippocampus from the thalamus, sept

200 In a subsequent experiment, disconnection of the HPC from the NAc shell using unilat

201 Contralateral, but not ipsilateral, disconnection of the IC and NAc core disrupted outcome d

202 s strategy features a counterintuitive early disconnection of the lactone subunit to a polycyclic eno

203 nt investigation found that inactivation and disconnection of the medial prefrontal cortex and basola

204 ng early diverging mammaliaforms, before the disconnection of the middle ear from the mandible in cro

205 rom alcohol was associated with a functional disconnection of the mPFC and CeA but not mPFC and nucle

206 Conversely, inactivation and disconnection of the orbitofrontal cortex and amygdala l

207 we have similarly observed that a functional disconnection of the PF-posterior dorsomedial striatal p

208 RF neurons in the mPFC during withdrawal and disconnection of the PFC-CeA pathway may be critical for

209 Disconnection of the portacaval shunt by left renal vein

210 Ablation end point was electrical disconnection of the pulmonary veins (PVs).

211 Disconnection of the two pathways during PIT also reveal

212 reduced ureteric bud branching, and delayed disconnection of the ureter from the common nephric duct

213 eceived a standard suctioning procedure with disconnection of the ventilator (20 secs, 14 F catheter,

214 the genetic manipulation toward a functional disconnection of the ventral hippocampal-prefrontal path

215 Lastly, disconnection of the white matter tracts connecting fron

216 Disconnection of these cortices in DH-compromised animal

217 Disconnection of this interface is thought to release co

218 This disconnection of trends suggests that perforated and non

219 opography was predominantly subcortical, and disconnection of white matter tracts critically contribu

220 Functional and structural disconnections of cortical networks may underlie various

221 Interestingly, disconnections of the VH from either the BA or PL elimin

222 Disconnections of varying step heights are displayed and

223 roaches to ring formation and retrosynthetic disconnection offer opportunities for chemists to explor

224 prefrontal-inferotemporal (PFC-IT) cortical disconnection on two recognition memory tasks, a "consta

225 twin boundaries through rearrangement of the disconnections on the Prismatic Basal interface; thereaf

226 dominant {1 0 -1 2} twinning is initiated by disconnections on the Prismatic Basal interfaces which e

227 ngement is pseudopericyclic with two orbital disconnections-one involving the nitrogen lone-pair orbi

228 Similar disconnections or gaps were observed in the provasculatu

229 shuffle mechanisms through gliding two-layer disconnections or pure-shuffle mechanisms through glidin

230 In Experiment 3, a functional disconnection paradigm was used to further examine the i

231 erspectives positing that a corticocortical "disconnection" partly explains cognitive aging.

232 nd continuous renal replacement therapy tube disconnection, pooled occurrence rate 0.24%) and 13 mino

233 Multimodal MRI biomarkers of frontoparietal disconnection predict 3-month outcome in our sample.

234 al group could not, indicating that BLA-pDMS disconnection prevented the acquisition of the new R-O a

235 possible neural substrate for the functional disconnection previously described in these patients, an

236 aine-seeking habit by using an intrastriatal disconnection procedure that combined a selective, unila

237 Here, we used an anatomical asymmetrical disconnection procedure to demonstrate that an interacti

238 Next, we used an anatomical disconnection procedure to determine whether projections

239 When a functional disconnection procedure was used to disrupt the interact

240 tance of the NAc-S to VP-m pathway we used a disconnection procedure, using asymmetrical inactivation

241 Finally, using a functional hemispheric disconnection procedure, we demonstrated that inhibition

242 , to test this, developed a novel sequential disconnection procedure.

243 The disconnection process is thought to be due to negative d

244 ect discrimination task, the same functional disconnection protocol with MUS did not affect the perfo

245 A retrosynthetic disconnection-reconnection analysis of epoxypolyenes-sub

246 We have defined a set of retrosynthetic disconnections representing robust reactions, amenable f

247 Furthermore, white matter disconnections resulting from damage along the superior

248 direct electrical stimulation) and permanent disconnection (resulting from neurosurgical resection) o

249 We show that this disconnection selectively decreased drug-seeking behavio

250 We found that the disconnection severely impairs serial reversal learning

251 Specifically, monkeys with functional disconnection showed less of a difference in error rates

252 Functional disconnection significantly affected performance in both

253 Importantly, through a series of 'disconnection' simulations, we showed that these changes

254 e stream-aquifer system can reach a critical disconnection state when the horizontal hydraulic gradie

255 g, viral-mediated gene silencing, functional disconnection strategies, pharmacologic rescue, and desi

256 This disconnection strategy benefits from the use of a simple

257 isoxazole components and represents a unique disconnection strategy for the synthesis of functionaliz

258 Subsequent disconnection studies revealed that disruption of top-do

259 major interhemispheric commissure, lack the disconnection syndrome classically described in callosot

260 disease (AD), which has been suggested as a disconnection syndrome manifested by the disruption of w

261 hypothesis of the existence of an underlying disconnection syndrome that causes clinical symptoms to

262 This loss leads to a hippocampal disconnection syndrome that drives clinical progression.

263 lthough most researchers consider it to be a disconnection syndrome with paroxysms driven by a loss o

264 , tinnitus can be regarded as a maladaptive 'disconnection' syndrome, which tries to both stabilize i

265 tex, implying an increased susceptibility to disconnection syndromes such as Alzheimer disease and sc

266 connections in two different mouse models of disconnection syndromes to demonstrate its utility for c

267 Beyond its application to classical disconnection syndromes, diffusion tensor magnetic reson

268 ic acids is emerging as a valuable synthetic disconnection that complements a wide range of conjugate

269 network; and a variable degree of structural disconnection that modulates this change in network func

270 Disconnections that include disclination content are con

271 han a biomimetic dimerization retrosynthetic disconnection, the anthracenyl ring systems are generate

272 epth in the stream, and at a steady state of disconnection, the maximum hydraulic gradient at the str

273 The target disconnection theory of amyotrophic lateral sclerosis (A

274 When disconnection times are sufficiently short, there is a s

275 ailable Zr(NMe(2))(4) affords an alternative disconnection to access alpha-arylated primary amines up

276 yclization, which constitutes a formal aldol disconnection to form a strained macrocycle.

277 c reaction examples and may identify the key disconnections to guide retrosynthesis.

278 lly defined neuronal populations and circuit disconnections to identify the pathways involved in the

279 ern that this method may overlook structural disconnections to seemingly spared regions and may fail

280 ther ipsilateral (control) or contralateral (disconnection) to the CeN lesion, and given overtraining

281 hypothesis more directly, rats were given a disconnection treatment using contralateral cytotoxic le

282 A double-allylation disconnection using a carvone-derived fragment was then

283 ncapped glomerulus lesion." Glomerulotubular disconnection was confirmed, but connection remnants bet

284 Functional disconnection was evident within 48 h, progressed throug

285 Prediction from indirect functional disconnection was scarce or negligible (0.01 < R2 < 0.18

286 to the learning of visual sequences, because disconnection was without effect on object-reward associ

287 In order to facilitate the electrical disconnection we used a low conductivity, silica-based E

288 pha), depressed mood, and feelings of social disconnection were assessed hourly.

289 Parameters estimating disconnection were entered in a general linear model to

290 can be altered from hydraulic connection to disconnection when the pumping rate exceeds the maximum

291 ateral motion of layer-by-layer nucleated GB disconnections, where both single-layer and double-layer

292 The strategy represents a new biocatalytic disconnection, which relies on an omega-TA-mediated aza-

293 ication of highly simplifying retrosynthetic disconnections, which indicated that the caged structure

294 the result of 1) an earlier onset of axonal disconnection with a consistent degeneration rate or 2)

295 hat link experiences of social connection or disconnection with health-relevant physiological respons

296 A criterion is suggested to distinguish disconnections with dislocation content from those with

297 tomatic CAD, which suggests that subcortical disconnection within large-scale cognitive neural networ

298 t-traumatic amnesia are caused by functional disconnection within the default mode network.

299 alterations in network connectivity, such as disconnections within the antigen/integrin receptor path

300 hways, leading to strategic cortico-cortical disconnections within the language network.