ライフサイエンスコーパス: discordant

1 high discordance when 3 or 4 parameters were discordant.

2 f DOAC adherence/persistence rates have been discordant.

3 itial predictions, and analyses are at times discordant.

4 d in rodents, while FAM46A was significantly discordant.

5 10-14.99) were independently associated with discordant 4D-CT results.

6 two groups: unhealthy lifestyle (15.6%) and discordant (84.4%).

7 oreover, the Ag-rich nanoscale precipitates, discordant Ag atoms, and Pb/Sr, Pb/Ba point defects in t

8 When target lesion selection was discordant, agreement was significantly reduced (assignm

9 5 binds to the central discordant alpha-helical region and induces a unique alp

10 ordant alternans becomes electromechanically discordant alternans as IKs or ISK increase.

11 r the first time the regulation of spatially discordant alternans by STIM1.

12 pid pacing, and the emergence of a spatially discordant alternans profile in STIM1-KD hearts.

13 astic pacing and the occurrence of spatially discordant alternans, an arrhythmia that is widely belie

14 susceptibility to the formation of spatially discordant alternans, resulting in an increased function

15 ic pacing on the nodal dynamics of spatially discordant alternans, we provide intuition for this obse

16 spatially concordant alternans to spatially discordant alternans, which is more arrhythmogenic than

17 or and propose control strategies to inhibit discordant alternans.

18 Discordant analysis showed one Lyra positive missed by V

19 Discordant analysis was performed using bidirectional se

20 me-wide biallelic pipeline removed 82.11% of discordant and 14.89% of concordant genotypes, and impro

21 d nonresponders and comparison of timing for discordant and concordant response assessments after ind

22 ne from the main and stability analyses were discordant and did not rule out an increased risk associ

23 ogression from visual fields (VFs) alone are discordant and have tradeoffs.

24 s to structural failure, and we suggest that discordant and lateralized patterns of associativity in

25 a clinical phenotype-dependent manner, with discordant and long-term nonprogressor patients showing

26 dissociation marked temporal heterogeneity, discordant and transitioning wavefronts patterns and com

27 rable CTPs, 81% both favorable profiles, 16% discordant, and 3% both unfavorable.

28 al epileptiform discharges are infrequent or discordant, and MRI does not reveal any apparent abnorma

29 Samples with discordant antigen profiles (negative for PfHRP2 but pos

30 be considered as they can be associated with discordant antimicrobial therapy.

31 nhanced susceptibility to VT/VF secondary to discordant APD alternans.

32 Our study found discordant associations of biochemically measured and ge

33 Three promising loci with sex-discordant associations were found (8535 female individu

34 se classifying strabismus into concordant or discordant based on the relationship between head positi

35 cremental glycemic responses were relatively discordant between CGMs, with a mean Kendall rank correl

36 For samples discordant between Clarity and the standard-of-care algo

37 acental findings, and infant outcomes can be discordant between co-twins with antenatal ZIKV exposure

38 Predominant first symptoms were usually discordant between family members.

39 or disease-specific therapy based on MWT was discordant between modalities in 20 patients (26%) (P <

40 LVH classification was discordant between modalities in 23 patients (29%) (P <

41 es (91%) for which SUVr image assessment was discordant between readers were classified as negative b

42 se distinctly different environments lead to discordant biology between parasites in host circulation

43 tic differences in genes expressed in these 'discordant' brain structures.

44 cardiac myocytes or spatially concordant or discordant Ca2+ and repolarization alternans in cardiac

45 iscordant, such as subcellular concordant or discordant Ca2+alternans in cardiac myocytes or spatiall

46 We classify these discordant calls and examine reasons for discordance.

47 L calls that were shown to be enriched among discordant calls but also in genomic regions with low se

48 Our method and analysis of discordant calls may further be useful for development,

49 A risk for discordant cancer may provide useful information about s

50 rder RR for melanoma in families of multiple discordant cancers.

51 familial associations of melanoma with other discordant cancers.

52 Discordant canonical introns, one nt apart, are present

53 was significantly associated with less POLST-discordant care (aRR, 0.93 per 10 years [95% CI, 0.88-1.

54 e significantly more likely to receive POLST-discordant care (comfort only: 29/64 [45%] vs 92/337 [27

55 e significantly less likely to receive POLST-discordant care than those without cancer (comfort only:

56 e significantly less likely to receive POLST-discordant care than those without dementia (23/111 [21%

57 For evaluating factors associated with POLST-discordant care, the outcome was ICU admission contrary

58 POLSTs, 38% (95% CI, 35%-40%) received POLST-discordant care.

59 One discordant case in 1 patient involved a discordant organ

60 Compared with concordant cases, discordant cases had higher frequencies of multigland di

61 The twelve discordant cases were then independently reviewed, leadi

62 In 188 (2.5%) discordant cases, SARS-CoV-2 loads were significantly lo

63 Concordant and discordant categories based on integrating CFR and maxim

64 ity risk gradient across the 4 concordant or discordant categories was independently driven by impair

65 Discordant categorizations were reconciled.

66 ings dying from the same causes) but not for discordant causes.

67 tion by eating meals ranked according to the discordant CGM was inversely correlated with each subjec

68 nts present in patients at >1 center, 23 had discordant classifications among centers (20.5%; Fleiss

69 Both concordant/discordant conditions were significantly associated with

70 of multimorbidity, including concordant and discordant conditions.

71 antify total multimorbidity, concordant, and discordant counts, and the effects of different combinat

72 el and the arbitration panel (32% and 30% of discordant CXRs, respectively).

73 inflammatory components, as well as specific discordant cytokine signatures of these two skin disease

74 site to detect and mechanistically interpret discordant data derived from patients with temporal patt

75 cept of LC as a prothrombotic state, discuss discordant data, and highlight the impact of the underly

76 Of the 34 discordant DBT-guided biopsies, 30 were architectural di

77 Infants with eczema by 18 months showed discordant development of bacterial genera of Enterobact

78 morbidity (total condition counts/concordant/discordant/different combinations of conditions), baseli

79 Unchanged was either no change or discordant directions of change.

80 donors, previously pregnant donors, and sex-discordant donors (male donor and female recipient or fe

81 s donors ranged from 9% to 25%, and from sex-discordant donors ranged from 44% to 50%.

82 ons from female, previously pregnant, or sex-discordant donors were not significantly associated with

83 ospinal fluid (CSF) and plasma may result in discordant drug resistance mutations (DRMs) in the compa

84 Eight cases were discordant due to probe design differences, with focal a

85 Twelve metabolites had discordant effects by HT type and were associated with i

86 Metabolites with discordant effects by HT type were evaluated for associa

87 APP and PSEN1 mutations had discordant effects on Abeta production but similar effec

88 Free is less prone to favor a treatment with discordant effects on survival and days free of ventilat

89 relationships, but this is challenged by the discordant evolution of individual genes.

90 a multitude of mRNAs and proteins exhibited discordant expression changes upon DUX4 expression.

91 oth muscle, and that this is mediated by the discordant expression of cyclooxygenase genes in epithel

92 In humans, discordant expression of IFNG and IFNG-AS1 was evident i

93 Discordant expression of YY1 and PLZF, therefore, might

94 s, and identify a set of homeolog pairs with discordant expression.

95 consistent and provide new diverse leads for discordant familial association of melanoma.

96 The remaining 61 (24%) individuals had discordant findings (MRI SEV-ECHO MOD or MRI MOD-ECHO SE

97 rapy on breast cancer remains unsettled with discordant findings from observational studies and rando

98 colonic segments, which were re-examined for discordant findings.

99 concordant for 513 (81%) of 634 patients and discordant for 121 (19%) of 634.

100 ere we study monozygotic and dizygotic twins discordant for ASD to test whether fetal and postnatal m

101 The study of monozygotic twins discordant for attention deficit hyperactivity disorder

102 , that are shared by identical twins who are discordant for cannabis exposure.

103 A total of 127 twin pairs were discordant for carrying a mutation, and in 61 (48%) case

104 In pairs discordant for CHIP mutations, we tested if the affected

105 direct comparison among twin pairs that were discordant for CHIP mutations.

106 gister, we identified all full-sibling pairs discordant for height.

107 We recruited 5 pairs of MZ twins discordant for idiopathic PD and established skin fibrob

108 hort of 43 monozygotic twin pairs clinically discordant for MS and searched for disease-related perip

109 d population controls, with female relatives discordant for pregnancy, and with pre- and postpregnanc

110 iblings (odds ratio=0.35, 95% CI=0.24, 0.51) discordant for pregnancy.

111 ed cerebral organoids from monozygotic twins discordant for psychosis.

112 Likewise, documentation was discordant for reporting glare (48.1% [78 of 162]), pain

113 Two additional monozygotic twin pairs discordant for schizophrenia also confirmed the excess G

114 ived neurons of monozygotic twins from pairs discordant for schizophrenia enhances disease-specific s

115 and 20 dizygotic (DZ) proband pairs con- or discordant for schizophrenia spectrum disorders, along w

116 peripheral blood RNA from monozygotic twins discordant for schizophrenia, and identified a schizophr

117 Regurgitation severity was discordant for seven pulmonary valves, 22 mitral valves,

118 e, 3563 families included siblings that were discordant for TD/CTD.

119 1.47 [95% CI, 1.36-1.69]), and when sibpairs discordant for treatment exposure were compared with sib

120 hin this population, 4128 (1.71%) pairs were discordant for treatment exposure.

121 sons were made of cognitive scores for twins discordant for victimization.

122 vious treatments, such risk perceptions were discordant from laboratory-evaluated fertility status am

123 In contrast, BCO2 variation is highly discordant from the species tree, with evidence of cross

124 However, trait evolution along discordant gene trees can also generate these incongruen

125 rds for estimating the mRNA abundance of the discordant genes reported here.

126 st of the genome, and yet detect a number of discordant genomic regions consistent with ancient admix

127 The bias analysis showed negligible bias by discordant genotypes.

128 by any guidelines, including the approach to discordant GFR measurement and estimated GFR results, th

129 Compared with the new nurses in the discordant group, those in the unhealthy lifestyle group

130 low-diversity virus populations in vitro The discordant high-fidelity phenotypes in this study highli

131 Discordant ID and mecA results were resolved by rpoB gen

132 s were identified based on the concordant or discordant impairment of maximal MBF or CFR.

133 16%) cases, partially concordant in 74%, and discordant in 10%.

134 utations in CTC and corresponding tumor were discordant in 11 of 26 "tumor-CTC-pairs" (42%), while 15

135 ore laboratory and site interpretations were discordant in 16% (683 of 4347), most commonly because o

136 -DOTATATE and (18)F-FDG PET/CT findings were discordant in 65 patients (62.5%) and concordant in 39 p

137 GCL that were either absent or directionally discordant in bulk hippocampus data.

138 ta suggest that GAT values are significantly discordant in eyes with thin corneas and advanced glauco

139 tor alpha, and interleukin 2) responses were discordant in frequency and function between BAL and blo

140 au PET and neurodegeneration biomarkers were discordant in most individuals who would be categorised

141 additional independent reviews of CXRs with discordant interpretations at the primary reading, blind

142 ng results, with consensus being reached for discordant interpretations.

143 secondary end point was association between discordant IOP measurements and the stage of glaucoma, a

144 urements, as well as the correlation between discordant IOP values and stage of glaucoma.

145 nemases or non-carbapenemase producers, with discordant isolates being primarily Guiana extended-spec

146 Discordant lesions (visible on only the 1-h images or on

147 Discordant lesions were verified during at least 30 mo o

148 both 1-h and 3-h (64)Cu-DOTATATE PET) and 5 discordant lesions, of which 4 were considered true.

149 th Bounded Confidence Model (RBCM), in which discordant links are broken until convergence is reached

150 ared across different ethnicities, but among discordant loci, we observed strong enrichment of varian

151 binds H-2D(k) In tandem, these functionally discordant Ly49 self-receptors increase NK cell prolifer

152 These parameters can be discordant, making the assessment of MR challenging.

153 of 2565 women (age range, 50-64 years) with discordant mammographic findings were discussed at conse

154 Conclusion Consensus review of discordant mammographic screening-detected abnormalities

155 Current diagnostic approaches are based on discordant measures, suffer from subjectivity and are in

156 At baseline, 3 nodal groups demonstrating discordant metabolic activity by both (18)F-FDG PET/CT a

157 Discordant metabolite effects between HT regimens may pa

158 y of methyltransferases or demethylases, yet discordant methylation patterns have also been observed,

159 ray ordering depends on the "weeding out" of discordant microtubules through frequent catastrophe-ind

160 e crossovers could facilitate the removal of discordant microtubules.

161 ene expression patterns of CSF cells from MS-discordant monozygotic twin pairs.

162 estimated for AUD onset given divorce among discordant monozygotic twins to equal 3.45 and 3.62 in m

163 mated odds ratio for drug abuse in pregnancy-discordant monozygotic twins was even stronger, at 0.17

164 terval was similar to that seen in pregnancy-discordant monozygotic twins, at 0.22 (95% CI=0.19, 0.26

165 Increasing total and discordant multimorbidity counts were associated with lo

166 esting should be considered for gliomas with discordant neuroimaging and FISH results.

167 lecular orbital analysis suggests that these discordant observations are a manifestation of the high

168 sex sibling pairs deliberately sampled to be discordant on sex-specific birth weight for gestational

169 Cousins and siblings who were discordant on smoking during pregnancy and severe mental

170 One discordant case in 1 patient involved a discordant organ system (lymph node) detected on 3-h but

171 dy population region might contribute to the discordant outcomes.

172 alyze the potential confounders behind these discordant outcomes.

173 The discordant P2 patterns are still spatially random, but t

174 cur depending on initial conditions with the discordant P2 patterns being spatially random.

175 hen the DGF is positive, both concordant and discordant P2 patterns can occur.

176 When DGF is absent, concordant and discordant P2 patterns occur depending on initial condit

177 e integration of non-trivial signatures from discordant paired-end alignments, split-reads and read d

178 eeksv simultaneously uses split read signal, discordant paired-end read signal, read depth signal and

179 nformation from both exon-exon junctions and discordant paired-end reads.

180 Most approaches that use discordant paired-end sequences ignore non-trivial signa

181 nce Model, under which the interaction among discordant pairs of users is allowed even with a negativ

182 Forty percent (17 of 42) of discordant pairs were positive in the LRT but negative i

183 enabled the determination of concordant and discordant pathways between these diseases.

184 e (MAPK) signaling and ALK pathways, whereas discordant pathways included advanced glycosylation end

185 Our data show a high burden and discordant pattern of HBV infection in rural couples, an

186 Most survivors with discordant perceptions overestimated risk (ie, perceived

187 s with concordant (both ratios >1 or <1) and discordant performance by ERRAGG and ECORAGG.

188 nformation-seeking incidence from 0.329 (for discordant physicians) to 0.357 (IRR, 1.085 [CI, 1.026 t

189 y later cognitive integration of variable or discordant pieces of information.

190 in 2 systems may increase risk of guideline-discordant prescribing.

191 dds of receiving thrombectomy as compared to discordant profiles (aOR = 3.97, 95% CI = 1.97-8.01, p <

192 Patients with discordant profiles achieved reasonable functional indep

193 unctional independence as compared to 38% in discordant profiles and 0% when both were unfavorable (p

194 Discordant PSMA-positive skeletal findings were examined

195 On follow-up testing, of 11 HCWs with discordant QFT-Plus results, 90.9% (10/11) had a negativ

196 such as late precordial transition (TZ) and discordant QRS axis may not be solely explained by aniso

197 However, there was a high discordant rate with HTS identifying 55 (38.7%) more pat

198 tly we calculated conversion rates, analyzed discordant rates between SNVs called with HG19 or HG38,

199 SViCT extracts discordant read pairs, one-end anchors and soft-clipped/

200 ve, single-institution studies, resulting in discordant recommendations.

201 P inhibitors and statins was associated with discordant reductions in LDL-C and apoB levels and a cor

202 e third of patient and provider reports were discordant regarding whether costs were discussed.

203 nts that demonstrated the counterintuitive ("discordant") relationship between education and schizoph

204 The GDT utilizes genotype differences of all discordant relative pairs to assess associations within

205 s with high-quality information and identify discordant replicates in structure profiling experiments

206 the participant level, 33.8% (54 of 160) had discordant reporting of blurry vision between the ESQ an

207 A new study by Ahn and Root reconciles these discordant reports by demonstrating that synergy emerges

208 reening with the reverse-sequence algorithm; discordant results (e.g., enzyme immunoassay [EIA] react

209 Background When there are discordant results between individual readers interpreti

210 We reconciled previous discordant results between mouse and human B cells and r

211 The majority of discordant results between QFT and QFT-Plus TB1 (84.8%)

212 f the WGS data provided explanations for the discordant results between TB&S and WGS data, revealed t

213 ffects [HTEs]) can be hidden in, and explain discordant results between, treat-to-target BP trials.

214 There were 16 samples with discordant results compared to the LDT results, five of

215 0.92; Wald tests, P < 0.001), entailing more discordant results for rare and novel variants.

216 e-breaker NAAT resolved all but three of the discordant results in favor the Xpert test.

217 Discordant results included five Bordetella bronchisepti

218 Sera from two individuals had discordant results on the different assays; both were ne

219 s 7.33 (95% CI 2.70-19.95) for patients with discordant results potentially leading to under-treatmen

220 Analysis of discordant results revealed that all four samples missed

221 inition, and specific measures to understand discordant results should also be included.

222 The increased risk among those with discordant results supports their conjoined use for risk

223 After reclassification of discordant results using CrAg enzyme immunoassay testing

224 Discordant results were further reviewed for changes in

225 These discordant results were in part due to diverse experimen

226 Discordant results were retested with both assays and by

227 Specimens with discordant results were tested with the cell cytotoxicit

228 Two recent randomized trials produced discordant results when testing the benefits and harms o

229 sensitivity, TPPA is preferred to adjudicate discordant results with the reverse sequence algorithm o

230 80.0%-88.6% of patients; among patients with discordant results, ADC showed better performance than K

231 herapy (DOT) of antifungals in patients with discordant results, and overall antifungal DOT/1,000 pat

232 by glutamate dehydrogenase and toxin EIA; if discordant results, specimens were reflexed to NAAT) and

233 here are limited data in large cohorts, with discordant results, that is, PCR-positive/EIA-negative (

234 panel organisms was 89% before resolution of discordant results.

235 Discordant rifampicin susceptibility results of Xpert MT

236 ACS) or whether differences are explained by discordant risk factors.

237 (49%) positive for a RV, 37% (42 of 115) had discordant sample pairs.

238 Six (0.8% of total) discordant samples lacked PfHRP2 but were positive for p

239 Chek Complete; Techlab), with GDH-and-toxin discordant samples tested with CCNA.

240 The remaining 3 discordant samples were negative by PET-PCR.

241 results with the Aries assay for nine of 14 discordant samples.

242 The association of these discordant SBP targets with cognition and differences by

243 The factors that contributed to discordant scores suggest potential approaches to improv

244 Studies with discordant scoring were identified and evaluated to unde

245 Abnormalities detected at discordant screening mammography readings were discussed

246 ed to study gait adaptability in response to discordant sensorimotor stimulations.

247 rrangement data in MLGO resulted in a highly discordant set of relationships inconsistent with both s

248 genic variants to structure into genetically discordant sets of antigenic types (e.g. serotypes).

249 . consensus calling methods) on the smaller, discordant share of the genome (20-30%) which might resu

250 cted in genital or rectal secretions, termed discordant shedding (DS).

251 cy with offspring depression and performed a discordant sibling analysis.

252 We develop a method of analysis [affected to discordant sibling pairs (A2DS)] that tests if shared va

253 st individuals are compared with a cohort of discordant sibling pairs (CDS) to derive a comparative s

254 sis of whole genomes of 1,786 phenotypically discordant sibling pairs from the Simons Simplex Collect

255 Subsequent targeted NGS in 24 discordant sibling pairs identified 17 nonsynonymous cod

256 .53; odds ratio=1.24, 95% CI=0.93, 1.66) and discordant-sibling (hazard ratio=0.97, 95% CI=0.68, 1.37

257 psychiatric control group, and four using a discordant-sibling control group.

258 Discordant-sibling designs effectively addressed surveil

259 ta-analysis, neither psychiatric control nor discordant-sibling designs supported an association betw

260 metry, in toenail clippings of 1,217 disease-discordant sister pairs in the US-based Sister (2003-200

261 Most of the discordant SNVs had low read depth, were low confidence

262 d more SNVs which failed conversion and more discordant SNVs than the opposite conversion (HG19 to HG

263 led with HG19 or HG38, and characterized the discordant SNVs.

264 results were reported for 17 (FP only) of 27 discordant specimens.

265 None of the 15 discordant spots had a morphologic correlate on the corr

266 compared with esophagectomy due to potential discordant staging.

267 ence of stress testing or in the presence of discordant stress test results and angiographic findings

268 (ESMO-MCBS v1.1) for substantial benefit, 37 discordant studies were identified.

269 al period-2 (P2) and spatially concordant or discordant, such as subcellular concordant or discordant

270 Early goal-directed therapy has shown discordant survival outcomes in sepsis studies.

271 Discordant syphilis test results, with a reactive nontre

272 f participants (95% CI: 95.4%, 100.0%); with discordant target lesion selection, readers agreed in on

273 Nine of these discordant targets were considered to represent true pos

274 nce interval, 0.84 to 0.92), 33 children had discordant test results.

275 and CDI risk factors, were compared between discordant test results.

276 st management recommendations for those with discordant test results.

277 (Clarity) concentrations between groups with discordant test results.

278 Twenty-one cases were concordant and 7 were discordant; the mean follow-up was 4.1 years.

279 (177)Lu-PSMA achieved discordant therapy responses with both regressive and pr

280 evidence for EPA and DHA and advanced AMD is discordant, though there was no association with advance

281 For units from sex-discordant transfusions, hazard ratios were 1.02 (95% CI

282 LTBI contacts could not be classified due to discordant TST and QFT results.

283 Thirteen patients had TERT(mutant) discordant tumors; seven of these had a single tumor wit

284 ood cells from females of HIV-uninfected sex-discordant twins are more activated (p = 0.01) and more

285 Microbiome-discordant twins display more dissimilar viromes compare

286 ch can be either concordant (T2D related) or discordant (unrelated), as a way of understanding the bu

287 ned the frequency, causes, and resolution of discordant variant classifications in the Sarcomeric Hum

288 Of the 54 originally discordant variants that underwent further review, 32 re

289 e across three laboratories was assessed and discordant variants were reviewed via teleconference and

290 nt girls with a similar level of obesity but discordant VAT/(VAT + SAT) ratios.

291 luenzae isolates, which were more frequently discordant when detected at low concentrations (S. aureu

292 y superior clinical outcomes and is at times discordant with patient desires.

293 Decisions are often discordant with patients' preferences.

294 revious germline testing; four of these were discordant with prior tumor screening.

295 emiology of maternal HCMV infections appears discordant with strategies for vaccine development.

296 If high frequency oscillations sources were discordant with the epileptogenic zone or resection area

297 received intensive care that was potentially discordant with their POLST.

298 Observational analyses were frequently discordant with those derived from MR.

299 eight specimens generated results that were discordant with those from the xTAG RVP and were further

300 ts submitted as P and LP, respectively, were discordant with VUS.