ライフサイエンスコーパス: disease entity

1 hes, outcome, and prognostic factors of this disease entity.

2 and could therefore be regarded as a single disease entity.

3 nd genotypic features characteristic of each disease entity.

4 needed to better understand and manage this disease entity.

5 ests that Kleine-Levin syndrome is a genuine disease entity.

6 asting doubt on its acceptance as a distinct disease entity.

7 lassified by itself or considered a distinct disease entity.

8 h, are managed clinically as if they are one disease entity.

9 -cell lymphoma has been established as a new disease entity.

10 e diagnosis and study of this underdiagnosed disease entity.

11 de additional evidence that each is a unique disease entity.

12 filling the diagnostic criteria for a single disease entity.

13 fication to recognize BIA-ALCL as a separate disease entity.

14 no reports of its use in patients with this disease entity.

15 s familial disorder may be a new or distinct disease entity.

16 abetes mellitus (here: aDM) is not a uniform disease entity.

17 f diseases of both organs, regardless of the disease entity.

18 of the plasmatic coagulation cascade in this disease entity.

19 uggesting it should be considered a separate disease entity.

20 IgA bullous dermatosis (LABD) or a separate disease entity.

21 EB should be considered a distinct molecular disease entity.

22 ation of ERBB2-low breast cancer as a unique disease entity.

23 cterize the genetic contribution to this new disease entity.

24 hat CRC-PM should be perceived as a distinct disease entity.

25 g that they should be classified as a single disease entity.

26 of ET and PMF do not represent a homogenous disease entity.

27 d show the role of de novo mutations in this disease entity.

28 an drive new therapeutic strategies for this disease entity.

29 of MAC and the clinical implications of this disease entity.

30 d variants describe the etiology of a single disease entity.

31 tion in one of the genes associated with the disease entity.

32 ated essential thrombocythemia is a distinct disease entity.

33 to other complications suggesting a distinct disease entity.

34 s for follow-up of patients with this unique disease entity.

35 mphoma remains an incompletely characterized disease entity.

36 al endothelial disorder, or a completely new disease entity.

37 s and incidence rates of over 120 recognized disease entities.

38 stology could indicate biologically distinct disease entities.

39 mor subtypes represent biologically distinct disease entities.

40 and endometrioid) likely represent distinct disease entities.

41 ly led to their classification into separate disease entities.

42 nize subtypes of low grade B-NHL as separate disease entities.

43 clinically and immunophenotypically distinct disease entities.

44 rally considered to be separate and distinct disease entities.

45 disease continuum but do represent separate disease entities.

46 ft ventricular filling pressures in specific disease entities.

47 d blasts (ie, 5% or more) were recognised as disease entities.

48 nplace assumptions about specific infectious disease entities.

49 eatures that may help to differentiate these disease entities.

50 as been presented as an approach to evaluate disease entities.

51 rporated into frontline settings for various disease entities.

52 ncluded in DSM and ICD are actually discrete disease entities.

53 as a component of standard of care for these disease entities.

54 with clinical and genomic features to define disease entities.

55 minate origin with an increasing spectrum of disease entities.

56 different cell identities, representing two disease entities.

57 ly ill patients not fitting into established disease entities.

58 opular since the late 18th century, to proto-disease entities.

59 iatric EoE and adult EoE represent different disease entities.

60 yndromes and sheds light on newly recognized disease entities.

61 ity, motivating alternative biomarker-driven disease entities.

62 e biological underpinnings of these multiple disease entities.

63 associations might help classifying involved disease entities.

64 BCL, suggesting that they represent distinct disease entities.

65 pitope specificity was not linked to certain disease entities.

66 ffective treatment for a number of difficult disease entities.

67 MDS leading to improved distinction of these disease entities.

68 e common between neurodegeneration and other disease entities.

69 nable new strategies for treatment of select disease entities.

70 ting the notion that they represent distinct disease entities.

71 molecularly characterized 31 separate muscle disease entities.

72 d should be considered biologically separate disease entities.1 These subtypes are esophageal adenoca

73 ar abnormalities that distinguish biological disease entities; (2) mutations, typically arising in su

74 Free-living amoebae cause three well-defined disease entities: a rapidly fatal primary meningoencepha

75 cohorts of patients diagnosed with a single disease entity, acute myeloid leukemia in first complete

76 genetic evidence for differentiating the two disease entities (AMAN and AIDP) and focuses our attenti

77 is hindered by limited understanding of the disease entity among practitioners, low access to diagno

78 multiple geographic settings, ethnic groups, disease entities and caregiver types, to more fully eval

79 simulate the performance of XPCI on various disease entities and compare proposed XPCI systems in an

80 38% cited efforts to expand beyond approved disease entities and dosing strategies, respectively.

81 ompounds that are effective across different disease entities and organs.

82 modeling strategy used by the HPO to define disease entities and phenotypic features and distinguish

83 tic strategies that account for the discrete disease entities and their plasticity.

84 r with the imaging findings of the different disease entities and to evaluate them together with the

85 NRM point estimates varied across disease entities and were highest in patients with mantl

86 uded studies with <50 patients with a single disease entity and mixed liver disease etiologies (with

87 sequencing alone by 8-36%, depending on the disease entity and tissue probed.

88 there is debate about whether it is a single disease entity and what role ANCA plays in its pathogene

89 that alter the response to therapy for some disease entities, and more will follow as pharmacogeneti

90 hat have been made about mental disorders as disease entities; and examine the evidence that mental d

91 -the art use of CT and US in diagnosing this disease entity; and to address the role of medical imagi

92 tor and sensory function are identified, new disease entities are being described and novel therapeut

93 heimer's disease (ADAD) comprises a distinct disease entity as compared to the far more prevalent for

94 lastic lymphoma associated with MCD is a new disease entity associated with HHV-8 infection.

95 These needs cross disease entities but some are disease specific.

96 glomerulosclerosis (FSGS) is not a specific disease entity but a lesion that primarily targets the p

97 thermore, idiosyncratic DILI is not a single disease entity but rather a spectrum of rare diseases wi

98 , suggesting that CIDP may not be a discrete disease entity but rather a spectrum of related conditio

99 atory myositis in children includes multiple disease entities, but is primarily made up of juvenile d

100 , cirrhosis has been seen to be not a single disease entity, but one that can be subclassified into d

101 hy, the final impression should identify the disease entity by name to assist the referring physician

102 ulation is further underscored by a distinct disease entity called IgG4-related disease (IgG4-RD), a

103 As many disease entities can be confused with POTS, it becomes c

104 itral flow velocity curves obtained from one disease entity can be valid in other disease states.

105 Here, we explored the presence of distinct disease entities characterized by specific pathophysiolo

106 nephritis (KIN) is a rare renal interstitial disease entity characterized by large tubular nuclei, ac

107 ed significance (CCUS) represents a distinct disease entity characterized by myeloid-related somatic

108 LOF mutations underlie a previously unknown disease entity characterized by SCD with normal EST that

109 and DLB may in fact represent 1 overlapping disease entity, characterized by the presence of mixed n

110 AK2 haplotype, designated 46/1, in all three disease entities compared to healthy controls (polycythe

111 thus whether the presence of one of the two disease entities could drive the onset or progression of

112 the International Lymphoma Study Group, the disease entities currently recognized in the literature

113 Although commonly thought of as 2 separate disease entities, CVD and cancer possess various similar

114 Despite the rise in these disease entities, detailed long-term outcomes of large N

115 that chronic ITP in childhood is a separate disease entity, dissimilar in many aspects to the newly

116 eosinophilic esophagitis (EoE) as a separate disease entity driven by allergic inflammation.

117 Several disease entities either selectively affect or spare the

118 complex psychiatric syndrome, not a unitary disease entity, encompassing a broad spectrum of psychop

119 ptic abscesses have been recognized as a new disease entity, especially in adults.

120 tion, accurate and precise classification of disease entities facilitates the discovery of the molecu

121 Therefore, we propose a new disease entity-familial encephalopathy with neuroserpin

122 s esophagus remains a particularly important disease entity for which we should maintain up-to-date g

123 aced with the need to establish the "curated disease entity" for gene-phenotype validity and variant

124 We have gathered annotations for disease entities from two curators, analyzed their disag

125 CXCL9, and CXCL10, which distinguished this disease entity from idiopathic pulmonary fibrosis and an

126 lescintigraphy can clearly differentiate one disease entity from the other.

127 ave historically been approached as a single disease entity given the uniform association with poor c

128 man and help to define the concept for a new disease entity hallmarked by idiopathic generalized seiz

129 Several disease entities have been shown to predispose to hepato

130 ng five pathogenic types, each with specific disease entities: immune-complex GN, pauci-immune GN, an

131 tomography (HRCT) findings in this group of disease entities in correlation with the clinical manife

132 to generate an annotated dataset that links disease entities in text to disease entries in a databas

133 rors are caused by the absence of associated disease entities in the abstract.

134 ded, the knowledge of co-occurrence of these disease entities in the same individuals grew.

135 there are a limited number of structures and disease entities in the temporal bone with which one mus

136 TS has gained greater recognition as a major disease entity in children younger than 5 years.

137 of positive reactions and confirmed ACD as a disease entity in children.

138 CRS has been regarded as a single disease entity in clinical and genetic studies in the pa

139 ive mutations in FAT1 cause a distinct renal disease entity in four families with a combination of SR

140 ilure (MethHF) is an increasingly recognized disease entity in the context of a rising methamphetamin

141 lymphoma (PMBL) is recognized as a separate disease entity in the REAL classification.

142 familial myeloid malignancies as a separate disease entity in the revised WHO classification has ren

143 whether pre-diabetes is itself an actionable disease entity, in addition to the risk factors characte

144 Disease entities included were tetralogy of Fallot (TOF)

145 l approaches to diagnose and treat different disease entities including those related to the over-nut

146 v(3)/t(3;3) myeloid malignancies as a single disease entity irrespective of blast count.

147 rope, the median age at diagnosis across all disease entities is 69 years.

148 The delineation of disease entities is complex, yet recent advances in the

149 sal of the names that are used as labels for disease entities is therefore a necessary and perpetual

150 CLL as a disease entity is defined by a relatively parsimonious s

151 lenging to diagnose, and recognition of each disease entity is frequently delayed.

152 Recognition of this rare disease entity is important as it can be mistaken for a

153 clude the disease entity/pathogenic type (if disease entity is not known) followed in order by patter

154 of paradoxical embolism are recognized, the disease entity is still rarely considered and remains un

155 The pathophysiology of this disease entity is unknown although several theories, inv

156 mosome 17 type (FTDP-17), a recently defined disease entity, is clinically characterized by personali

157 While predominant as a disease entity, knowledge voids exist regarding the path

158 We describe a recently recognized disease entity, limbic-predominant age-related TDP-43 en

159 mal neutrophilic IgA dermatosis, a rare skin disease entity manifested with blisters and pustules cli

160 Various disease entities may cause dizziness, and the reported f

161 ology and psychiatric symptoms, true natural disease entities may not exist in psychiatry.

162 axia (gluten ataxia) and suggested that this disease entity may account for a large number of patient

163 al wall appear to be highly conserved across disease entities, modulating inflammation in atheroscler

164 ve recently been established to define a new disease entity, MOG-antibody-associated disease (MOGAD),

165 mains as to whether this represents a single disease entity, namely mixed connective tissue disease,

166 understanding of the molecular basis of the disease entity, new insights in risk stratification or o

167 oted no significant difference in NRM across disease entities (NHL: 4.2%, MM: 6.2%, p = 0.22).

168 A list of major recommended human and animal disease entities (nomenclature) is provided in alignment

169 in immunostaining in the human brain and the disease entity now recognized as PD remains to be determ

170 al processes underlying chronic inflammatory disease entities of different etiology.

171 This novel disease entity often prompts comparisons with, and extra

172 This review focuses on selected disease entities, operative techniques, perioperative ma

173 on remains whether CLIPPERS is an actual new disease entity or represents a syndrome that includes di

174 ggesting that we are identifying a different disease entity or stage.

175 The primary diagnosis should include the disease entity/pathogenic type (if disease entity is not

176 ositis syndromes comprise multiple, distinct disease entities, perhaps arising from divergent pathoge

177 Nodal MZL seems to be a distinctive disease entity rather than an advanced stage of MALT-typ

178 DLBCL, previously recognized as a single disease entity, represents a heterogeneous group of dise

179 primary IgA nephropathy (IgAN) are separate disease entities requiring different treatment approache

180 Some of these disease entities seem to be disappearing over time and t

181 ty with increasingly severe OSA because both disease entities share common inflammatory pathways, act

182 these manifestations represent two distinct disease entities sharing inflammatory demyelination as a

183 ese results, obtained in diverse hematologic disease entities, show that common targets (TE) activate

184 VEGF levels between POEMS patients and other disease entities showing higher serum VEGF in POEMS synd

185 sease (IgG4-RD) has only existed as a unique disease entity since 2003, yet remarkable progress has a

186 Biliary dyskinesia consists of two disease entities situated at two different anatomical lo

187 with worse outcomes in every cardiovascular disease entity studied.

188 Some disease entities such as 'wheat-dependent exercise-induc

189 elet microparticle participation in specific disease entities such as rheumatoid arthritis has been e

190 curves cannot be used in patients with other disease entities, such as hypertrophic cardiomyopathy.

191 terns may be present); score/grade/class for disease entities, such as IgA nephropathy, lupus nephrit

192 evidence to demonstrate that a premalignant disease entity, such as MDS or colonic polyps, can be tr

193 Knowledge obtained from the study of these disease entities supports the hypothesis that both genet

194 This study reports a disease entity termed ENDI-agammaglobulinemia (ENDI-A) s

195 t IDH1(R132MUT) appear to represent distinct disease entities that arise from separate cell types of

196 kidney injury (AKI) is a common and serious disease entity that affects native kidneys and allograft

197 Depression is a disease entity that causes significant morbidity and mor

198 e-plaque parapsoriasis lesions as a separate disease entity that characteristically harbors a so far

199 POSE OF REVIEW: Prostate cancer is a complex disease entity that covers a wide prognosis spectrum.

200 orms of extrapulmonary tuberculosis, it is a disease entity that is very rare in Poland (less than 10

201 by multiple providers, misinformation, and a disease entity that, particularly when active, can adver

202 d joint involvement patterns between the two disease entities through multiple methods to build machi

203 e traditional approach of primarily defining disease entities through similar clinical features.

204 e understanding of this clinically important disease entity through a genome-wide association study.

205 The most important, recent infectious disease entity to consider is community-acquired methici

206 enic disorder is determining the appropriate disease entity to curate.

207 tive preclinical models for several of these disease entities together with analyses of human tumour

208 hough current treatment strategies lump most disease entities together, future treatments will includ

209 oach to the diagnosis and treatment of these disease entities using a case presentation format.

210 less, excellent discrimination between these disease entities was achieved by computing hemispheric a

211 er ETO functionally links a broader range of disease entities, we asked whether ETO forms a complex w

212 l vascular alterations attributable to other disease entities were excluded.

213 ), and others are increasingly recognized as disease entities, where dysregulated cytokines contribut

214 ong COVID is the patient-coined term for the disease entity whereby persistent symptoms ensue in a si

215 le that a classification is a list of "real" disease entities, which are defined by a combination of

216 In this article, we first review disease entities, which frequently present with the symp

217 Immunoactinopathies are rare disease entities with complex combinations of clinical m

218 We now know sAML comprises multiple disease entities with distinct clinical and biological f

219 Other cardiovascular disease entities with higher prevalence or unique consid

220 obstructive pulmonary disease (COPD) are two disease entities with overlapped clinical features, and

221 zophrenia and bipolar disorder--are distinct disease entities with specific genetic causes and neuroa

222 nt of the criteria used to identify distinct disease entities with widespread adoption of the 2001 Wo

223 ne mutations (biCEPBA) represents a distinct disease entity with a favorable clinical outcome.

224 ncer in particular is emerging as a specific disease entity with distinct molecular, pathologic, and

225 rovide definitive evidence that PPI-REE is a disease entity with significant molecular overlap with E

226 Each of these represents a distinct disease entity, with different clinical and pathologic f

227 dicate that driver mutations define distinct disease entities within PMF.

228 ingly, PsA is being recognized as a distinct disease entity worthy of research regarding reliable ass