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1 and the microbiome in order to predict human disease susceptibility.
2 de lysosomal function, enhancing Parkinson's disease susceptibility.
3 d might serve as a biomarker of exposure and disease susceptibility.
4 rovide new insights into human variation and disease susceptibility.
5 tic architecture both of gene expression and disease susceptibility.
6 l reveal additional variants contributing to disease susceptibility.
7 oms, suggesting their loss may contribute to disease susceptibility.
8 ontributing to chronic obstructive pulmonary disease susceptibility.
9 is more broadly associated with Parkinson's disease susceptibility.
10 ature of our genome in evolution, health and disease susceptibility.
11 gut that alters immune cell homeostasis and disease susceptibility.
12 differences to hepatic metabolism and liver disease susceptibility.
13 transmissible factor dramatically increased disease susceptibility.
14 is a predictor of lifetime neuropsychiatric disease susceptibility.
15 fying sex-specific molecular determinants of disease susceptibility.
16 and age-related physiological variation and disease susceptibility.
17 external influences and may thereby modulate disease susceptibility.
18 s contractility, ventricular remodeling, and disease susceptibility.
19 ach to identifying rare variants involved in disease susceptibility.
20 with additional potential as a biomarker of disease susceptibility.
21 cover rare variants that are associated with disease susceptibility.
22 re common but also have a powerful effect on disease susceptibility.
23 r phenotypic variation of complex traits and disease susceptibility.
24 ophils in inflammatory lesions and influence disease susceptibility.
25 n miRNAs should be explored as the basis for disease susceptibility.
26 an contact has been attributed to infectious disease susceptibility.
27 help to define principles for understanding disease susceptibility.
28 ms underlying human phenotypic variation and disease susceptibility.
29 tate expression levels of HLA associate with disease susceptibility.
30 defense mechanisms that may confer increased disease susceptibility.
31 significance in in vitro cell studies and on disease susceptibility.
32 g to unveil the genomic basis of periodontal disease susceptibility.
33 air to influence life from evolution through disease susceptibility.
34 namic changes in diversity, which can impact disease susceptibility.
35 intestinal microbiota may be associated with disease susceptibility.
36 h age-related changes in lung physiology and disease susceptibility.
37 influence host immune function and modulate disease susceptibility.
38 associations at loci yet to be implicated in disease susceptibility.
39 stic insights into functions associated with disease susceptibility.
40 e as well as functionally mapping regions of disease susceptibility.
41 on in a way that favors bacterial growth and disease susceptibility.
42 enic T cell response and therefore increases disease susceptibility.
43 ivate JA signaling as a mechanism to promote disease susceptibility.
44 = 1.84 x 10(-45)) as relevant positions for disease susceptibility.
45 ion is involved in human trait formation and disease susceptibility.
46 nd unveils genes governing pathogenicity and disease susceptibility.
47 ain links between microbiota composition and disease susceptibility.
48 ing of gut immune responses and inflammatory disease susceptibility.
49 characterize the contribution of genetics to disease susceptibility.
50 ow genetic effects interact to contribute to disease susceptibility.
51 actor in genetic differences in pneumococcal disease susceptibility.
52 iology, the status of the immune system, and disease susceptibility.
53 ctors or mutations might result in increased disease susceptibility.
54 variants in noncoding regions is central to disease susceptibility.
55 ator of Ab production, has a minor effect on disease susceptibility.
56 e a major contributor to genetic disease and disease susceptibility.
57 WAS) have identified many loci implicated in disease susceptibility.
58 host metabolite interactions which may alter disease susceptibility.
59 ction with MAPKKKepsilon and did not promote disease susceptibility.
60 -signaling pathways as contributors to lupus disease susceptibility.
61 t an important role for the IL-12 pathway in disease susceptibility.
62 have a negligible role in common autoimmune disease susceptibility.
63 t PrP is the major determinant of host prion disease susceptibility.
64 its receptor, are associated with autoimmune disease susceptibility.
65 ised in avenacin acylation and have enhanced disease susceptibility.
66 , indicating that these cells contributed to disease susceptibility.
67 c variation has a major impact on infectious disease susceptibility.
68 wing signs of association with meningococcal disease susceptibility.
69 ally informative in studies of evolution and disease susceptibility.
70 abiotic stress-response pathway, to promote disease susceptibility.
71 o telomere homeostasis, with direct links to disease susceptibility.
72 significant role in phenotypic variation and disease susceptibility.
73 is and Acropora palmata to quantify relative disease susceptibility.
74 nomenon that could shape viral evolution and disease susceptibility.
75 T14, the expression of which is required for disease susceptibility.
76 mechanism for sex differences in autoimmune disease susceptibility.
77 ic variation that plays an important role in disease susceptibility.
78 le of germline variation in the IGH locus in disease susceptibility.
79 i, none of which showed any association with disease susceptibility.
80 diate the function of GWAS loci on postnatal disease susceptibility.
81 role for nanoparticle exposure in increased disease susceptibility.
82 e response to microbial exposure in Behcet's disease susceptibility.
83 ed dynamic complexes associated with MTI and disease susceptibility.
84 IDO activity or depletion of Tregs restored disease susceptibility.
85 rdant with known differential cardiovascular disease susceptibilities.
86 insight into its roles in human disease and disease susceptibilities.
87 expression of plant immunity genes enhanced disease susceptibility 1 (EDS1) and isochorismate syntha
88 and functions upstream of the genes enhanced disease susceptibility 1 (EDS1) and N requirement gene 1
89 icylic acid (SA) pathway, including ENHANCED DISEASE SUSCEPTIBILITY 1 (EDS1), EDS1-LIKE 2 (EDL2), EDL
90 phytoalexin-deficient 4 (PAD4) and enhanced disease susceptibility 1 (EDS1), in guard cells that for
91 utoimmunity in cfs1 is dependent on ENHANCED DISEASE SUSCEPTIBILITY 1 (EDS1)-mediated effector-trigge
92 downstream immune signaling complex ENHANCED DISEASE SUSCEPTIBILITY 1 (EDS1)/PHYTOALEXIN DEFICIENT 4
93 ive immune responses and found that enhanced disease susceptibility 4 (eds4) displays alterations in
95 o the association between MHC haplotypes and disease susceptibility, a deeper understanding of MHC po
97 epression by PLZF depended on the rs12101261 disease susceptibility allele and was increased by IFNal
98 cular interest, the ATP7B(K832R) Alzheimer's disease susceptibility allele was found, for the first t
100 k for how to deal with identified hereditary disease susceptibilities and how to return the data to p
101 cal trial of 2159 infants with HLA-conferred disease susceptibility and a first-degree relative with
103 o complex diseases is crucial for predicting disease susceptibility and developing patient-tailored t
104 dy links a germline variant to Ewing sarcoma disease susceptibility and EWSR1-FLI1-mediated gene acti
105 ynpo-deficient mice demonstrated exacerbated disease susceptibility and increased intestinal permeabi
106 anscriptome that ultimately lead to prostate disease susceptibility and may serve as a source of the
107 ient history now influences human infectious disease susceptibility and microbiome homeostasis, and c
108 w social status is an important predictor of disease susceptibility and mortality risk in humans and
111 s largely independent of the contribution to disease susceptibility and point to a biology of prognos
113 as 'loss of function' variants, may have on disease susceptibility and quantitative levels of biomar
114 importance of the host genome in infectious disease susceptibility and severity and offer crucial in
115 Particular alleles of HLA contribute to disease susceptibility and severity in many autoimmune c
116 ntifying bacteria that preferentially affect disease susceptibility and severity remains a major chal
117 microbiota signature capable of transmitting disease susceptibility and subject to reprogramming by e
118 implicating CEV as a biomarker of aging and disease susceptibility and suggesting that it might play
119 cial experience is an important predictor of disease susceptibility and survival in humans and other
120 view evidence of the genetic contribution to disease susceptibility and the current state of molecula
121 ecular mechanisms by which these loci confer disease susceptibility and the extent to which shared lo
123 tionary forces that have shaped inflammatory-disease susceptibility and to elucidate functional pathw
124 nisms underlying PF4/heparin immunogenicity, disease susceptibility, and clinical manifestations of d
125 repertoires has been associated with aging, disease susceptibility, and differential response to inf
126 ice demonstrate a role for Il2 in autoimmune disease susceptibility, and for decades the proximal Il2
127 a (ALL) biology, including associations with disease susceptibility, and increased risk of central ne
128 ithin individuals may serve as a read-out of disease susceptibility, and is thus potentially a valuab
130 understanding how genetic diversity impacts disease susceptibility, and raises important concepts ab
131 iRNAs are emerging as putative biomarkers of disease, susceptibility, and perhaps dietary exposure.
133 We demonstrate that loci for inflammatory-disease susceptibility are enriched for genomic signatur
138 Indels can be deleterious and contribute to disease susceptibility as recent genome sequencing proje
139 -null mice revealed a remarkable increase in disease susceptibility associated with increased intesti
140 atures, we have developed a method, SuSPect (Disease-Susceptibility-based SAV Phenotype Prediction),
142 few studies have directly compared metabolic disease susceptibility between NNT-deficient 6J mice and
144 ardiovascular disorders, obesity, infectious disease susceptibility, blood disorders, neurosensory di
145 suppress plant immune responses and promote disease susceptibility but has also facilitated the disc
146 ing 9 (TNRC9; TOX3) has been associated with disease susceptibility but its function is undetermined.
147 le-specific methylation (hap-ASM) can impact disease susceptibility, but maps of this phenomenon usin
148 variants in these regulatory elements modify disease susceptibility by regulating the expression of g
150 nthesis gene expression and display enhanced disease susceptibility compared to wild-type plants.
151 in the miRNA binding sites, suggesting that disease susceptibilities could be attributed to ceRNA re
153 er on microbiome composition, and subsequent disease susceptibility, depended on the host genotype.
154 ce of Africa to studies of human origins and disease susceptibility, detailed characterization of Afr
155 ng mechanisms and patterns of variability in disease susceptibility, disease evolution, and drug resp
156 interaction databases to identify windows of disease susceptibility during development and the time p
157 r current understanding of RMS epidemiology, disease susceptibility factors, disease mechanisms and e
158 ntially be used to facilitate predictions of disease susceptibility for more precise and timely appli
160 n APOE varepsilon3/4 and another Alzheimer's disease susceptibility gene and demonstrate in proof of
161 species of Xanthomonas exploit a single host disease susceptibility gene by altering the expression o
163 cing a shocking incident, but the underlying disease susceptibility gene networks remain poorly under
164 ction protects mice deficient in the Crohn's disease susceptibility gene Nod2 from intestinal abnorma
166 cell survival, our data implicate TWEAK as a disease-susceptibility gene for a humoral immunodeficien
167 he sucrose transporter gene OsSWEET13 as the disease-susceptibility gene for PthXo2 and the existence
168 ssive resistance gene xa13, an allele of the disease-susceptibility gene Os8N3 (also named Xa13 or Os
169 f host-microbe intersection, notably several disease susceptibility genes and sterol metabolism pathw
170 ent studies identified over half of the HSCR disease susceptibility genes as targets for the sex-dete
171 y between drug targets, somatic mutants, and disease susceptibility genes by utilizing directionality
172 MED18 interacts with YIN YANG1 to suppress disease susceptibility genes glutaredoxins GRX480, GRXS1
174 ctors (TALEs) that activate transcription of disease susceptibility genes in the host, inducing a sta
175 uggest that autophagy and inflammatory bowel disease susceptibility genes regulate inflammatory respo
176 s have been successfully applied to identify disease susceptibility genes with genetic markers such a
181 xpression profile of specific transcripts of disease-susceptibility genes is for the first time descr
183 The risk factors are largely undefined but disease susceptibility has been associated with human le
187 ators (e.g., trimethylamine N-oxide) of host disease susceptibility have created novel potential ther
189 ssociated with chronic obstructive pulmonary disease susceptibility (HHIP, IREB2/CHRNA3, CYP2A6/ADCK,
190 f elevated IL18 levels on inflammatory bowel disease susceptibility (IBD) in 12,882 cases and 21,770
191 idate genes were tested for association with disease susceptibility in 2,101 cases and 4,202 controls
192 the different HLA-DR15 haplotype alleles on disease susceptibility in a new "humanized" model of MS
193 SPC Cre(+)) revealed a selective increase in disease susceptibility in Adora2b(loxP/loxP) SPC Cre(+)
196 nsights on the mechanism of disproportionate disease susceptibility in men and identify antiandrogeni
198 stimulation with this moiety alone overrides disease susceptibility in mice depleted of commensal bac
203 environmental stressors is known to increase disease susceptibility in unexposed descendants in the a
204 r-latitude hosts, we hypothesised that their disease susceptibility increases under 'thermal mismatch
205 ciation of autophagy with inflammatory bowel disease susceptibility, increasing evidence indicates th
206 microbiome assembly history can affect host disease susceptibility independent of microbiome composi
207 ty of effector-associated gene induction and disease susceptibility is attributable to a single nucle
208 Direct-to-consumer (DTC) genetic testing for disease susceptibility is largely dominated by 2 extreme
209 nical relevance of microbiome alterations on disease susceptibility is still in its infancy, but the
210 auterine conditions that influence offspring disease susceptibility is warranted to inform targeted e
211 G) allele, despite not being associated with disease susceptibility, is associated with a milder cour
212 models to mapping the genetic basis of human disease susceptibility, knowing whether a single disrupt
215 were mapped and examined for enrichment for disease susceptibility loci annotated in the genome-wide
216 rs interested in mapping common and uncommon disease susceptibility loci by focusing on output linkin
217 attempting to functionally interpret complex-disease susceptibility loci by GWAS and eQTL integration
219 erves as a good alternative method to detect disease susceptibility loci for clinic genomic data.
220 additional candidate-gene annotation for 37 disease susceptibility loci for human atherosclerotic di
221 nts, such as discoveries of large numbers of disease susceptibility loci from genome-wide association
223 Conversely, the aggregated effect of all 170 disease susceptibility loci was not associated with dise
228 pendent selection plausibly acted on a human disease susceptibility locus, a form of balancing select
229 unctional dissection of the CD33 Alzheimer's disease susceptibility locus, we found that the rs386544
230 variants and may help to predict or explain disease susceptibility more accurately and comprehensive
231 an association between SMAD5 levels and PAH disease susceptibility (odds ratio, 0.317; 95% confidenc
236 nduced inflammation contributes to metabolic disease susceptibility of the offspring via alterations
237 ow pH, and correlates with the difference in disease susceptibility of the two species, as expected f
238 ding how human genetics influence infectious disease susceptibility offers the opportunity for new in
243 activate the cognate host genes, leading to disease susceptibility or resistance dependent on the ge
244 entify immunological mechanisms that control disease susceptibility or resistance to provide novel ta
248 rstanding how these mechanisms contribute to disease susceptibility, particularly in infants with dev
249 ads to biallelic expression which may affect disease susceptibility possibly reflected in high levels
250 ical for signaling downstream of the Crohn's disease susceptibility protein nucleotide-binding oligom
251 terodimer and its potential association with disease susceptibility, provides a rationale for a poten
252 lowing inoculation and increased periodontal disease susceptibility, reflected by higher TNF levels a
253 -wide association studies indicate that many disease susceptibility regions reside in non-protein-cod
254 n, while BATF and ESRRA overlap other immune disease susceptibility regions, validating our approach
255 acteristics of ageing that lead to increased disease susceptibility remain inadequately understood.
258 ved in gene regulation whose contribution to disease susceptibility remains to be fully understood.
262 y HLA-DRB1 haplotypes was correlated between disease susceptibility, severity, and mortality, but inv
263 e cell receptors and proteins that determine disease susceptibility shed light on how different arms
265 umour (TGCT), revealing a polygenic model of disease susceptibility strongly influenced by common var
266 ests that fungal proteins involved in either disease susceptibility such as ToxB or resistance such a
267 enome-wide association studies contribute to disease susceptibility, systems genetics is likely to be
268 ngly, we revealed appreciable differences in disease susceptibility, temporal patterns, network struc
269 roles of innate immunity, sex differences in disease susceptibility, the necessity for adjuvants in e
270 exposure may therefore shed light on complex disease susceptibility.The goal was to analyze the progr
271 bial identities and how this might determine disease susceptibility, therapeutic responses and recove
272 numerous genome-wide association studies of disease susceptibility, there is increasing interest in
273 loci, these OA loci are thought to influence disease susceptibility through the regulation of gene ex
274 and double-mutant plants exhibited enhanced disease susceptibility to cucumber mosaic virus when the
277 methasone-inducible HopQ1 exhibited enhanced disease susceptibility to virulent Pto DC3000, the Pto D
279 to a more diverse ethnic group for gallstone disease, susceptibility to biliary cancer, and show vari
280 6D phosphomimetic mutants exhibited enhanced disease susceptibility upon surface inoculation with P.
281 We applied this method to meningococcal disease susceptibility, using the DNA binding pattern of
282 easures: Identification of a novel, germline disease susceptibility variant in a previously uncharact
290 the HLA-DRB1 locus, which is associated with disease susceptibility, was also associated with radiolo
292 ent is a critical epoch for neuropsychiatric disease susceptibility, we characterized the genetic con
293 Because Fcgamma receptors are implicated in disease susceptibility, we crossed HLA transgenic mice o
294 However, they demonstrate alterations in disease susceptibilities when exposed to a variety of va
295 utations of Nppa, Plod1, and Mthfr increased disease susceptibility, whereas Agtrap and Clcn6 mutatio
296 ironmental and genetic factors contribute to disease susceptibility, whereas the immunopathogenesis o
297 their reprogramming into Th2-like cells and disease susceptibility, whereas Treg-cell-lineage-specif
298 D have identified common variants underlying disease susceptibility, while gene expression microarray
299 uggests that at least 400 variants influence disease susceptibility, with potentially many thousands.
300 crobiome co-evolution drives homeostasis and disease susceptibility, yet regulatory principles govern